Immune cell cryopreservation device

Abstract

The utility model relates to the technical field of immune cell cryopreservation, in particular to an immune cell cryopreservation device which comprises a cryopreservation tank, a sealing cover is hinged to the top of the cryopreservation tank, and a lifting mechanism is arranged in the cryopreservation tank. According to the cryopreservation tank, the cryopreservation tube for preserving immune cells is placed in the placing groove in the top of the heat preservation partition plate for storage, so that most of the cryopreservation tube is still located in the cryopreservation tank after the sealing cover is opened, and the influence of external temperature difference on the immune cells in the cryopreservation tube when the cryopreservation tube is taken out is reduced; the sliding rods below the limiting rings can be driven to move together through rotation of the heat preservation partition plate, when the sliding rods move to the positions, located on the lifting protruding blocks, of the guide rings, the sliding rods can be jacked up due to the lifting protruding blocks, and therefore the cryopreservation pipes above are lifted up and lifted up from the interior of the containing groove, workers can take the cryopreservation pipes conveniently, and the problem that the cryopreservation pipes are prone to frostbite when deeply taken is solved.

Description

Technical Field

[0001] The utility model relates to the technical field of immune cell cryopreservation, in particular to an immune cell cryopreservation device. Background Technique

[0002] Immune cells refer to cells that participate in or are related to immune responses, including lymphocytes, dendritic cells, monocytes / macrophages, granulocytes, mast cells, etc. Immune cells can be divided into many types and play important roles in the human body. Immune cells are generally stored using cryopreservation devices. Common cryopreservation devices place immune cells in cryopreservation tubes and then place them inside the device body for cryopreservation. Since the temperature inside the device body is extremely low, when taking out and placing the cryopreservation tubes, it is easy to frostbite the palms, which is very inconvenient.

[0003] The prior art such as the published patent No. CN221011671U provides an immune cell cryopreservation device, which relates to the technical field of cryopreservation devices. It includes a cryopreservation box body, the top of the cryopreservation box body is movably installed with a box cover, the inside of the cryopreservation box body is movably installed with a placement plate, and a control mechanism for adjusting the position of the placement plate is also provided on one side of the bottom of the cryopreservation box body. A number of placement slots are evenly distributed on the upper surface of the placement plate, and a limit snap ring is movably installed inside each placement slot. By rotating the driving gear, under the meshing action between the driving gear and the driven gear, the adjusting screw rod can be controlled to rotate. Then, through the meshing between the adjusting screw rod and the screw sleeve, the height position of the placement plate can be adjusted, so that when the staff takes and places the test tubes, they will not come into contact with the inside of the cryopreservation box body, and the operation process is safer, effectively reducing the occurrence of frostbite.

[0004] In this solution, through the meshing between the adjusting screw rod and the screw sleeve, the height position of the placement plate can be adjusted, so that when the staff takes and places the test tubes, they will not come into contact with the inside of the cryopreservation box body, making the operation process safer. However, during actual operation, the placement plate drives multiple groups of test tubes to be lifted together from the low-temperature environment inside the cryopreservation box, causing all the test tubes to come into contact with the non-low-temperature external environment. This results in certain limitations on the selection time during actual use. For example, when selecting and taking out multiple samples, it is necessary to avoid the test tubes being in contact with the non-low-temperature external environment for a long time, which may affect the test tubes. In view of this, we propose an immune cell cryopreservation device. Summary of the Utility Model

[0005] The purpose of the utility model is to provide an immune cell cryopreservation device, which solves the problem of easy frostbite of the palms when taking out and placing the cryopreservation tubes.

[0006] To achieve the above purpose, the utility model provides the following technical solutions:

[0007] An immunocyte cryopreservation device, comprising a cryopreservation tank, a sealing cover is hinged to the top of the cryopreservation tank, and a lifting mechanism is arranged inside the cryopreservation tank;

[0008] The lifting mechanism includes a heat preservation partition board, the heat preservation partition board is rotatably connected to the top of the inner wall of the cryopreservation tank, a plurality of placement grooves are formed in the top of the heat preservation partition board, and the placement grooves are annularly distributed. The placement grooves are used for placing cryopreservation tubes. A guide ring is connected to the bottom of the inner wall of the cryopreservation tank, a lifting convex block is arranged on the top of the guide ring, a limiting ring is connected to the bottom of the heat preservation partition board through a connecting rod, and a sliding rod is slidably connected to the inner wall of the limiting ring corresponding to each placement groove.

[0009] Preferably, the position of the heat preservation partition board above the lifting convex block is not provided with a placement groove for staggering the cryopreservation tubes.

[0010] Preferably, brackets are connected to the tops of the sliding rods, and buffer pads are arranged on the brackets for protecting the cryopreservation tubes.

[0011] Preferably, guide wheels are connected to the bottoms of the sliding rods, and the guide wheels are in rolling connection with the top of the guide ring.

[0012] Preferably, a gear ring is connected to the top of the heat preservation partition board, a driving gear is meshed with the outer wall of the gear ring, a support is connected to the outer wall of the cryopreservation tank at a position below the driving gear, a hinge rod is hinged to the inner wall of the support, a rotating rod is rotatably connected to the top of the hinge rod, and the rotating rod is connected to the driving gear.

[0013] Preferably, a hand wheel is connected to the top of the driving gear, and a limiting block is arranged on the outer wall of the cryopreservation tank corresponding to the rotating rod.

[0014] Preferably, for the limiting block, a limiting groove is formed in the inner wall of the limiting block, sliding grooves are respectively formed on both sides of the inner wall of the limiting groove, and a clamping block is slidably connected to the inner wall of the sliding groove. Springs are connected between the inner walls of the sliding grooves and the clamping blocks.

[0015] By means of the above technical solution, the present utility model provides an immunocyte cryopreservation device, which at least has the following beneficial effects:

[0016] 1. The utility model reduces the influence of the external temperature difference on the immune cells in the cryopreservation tube when the cryopreservation tube is taken out by placing the cryopreservation tube for storing immune cells in the placement groove at the top of the heat preservation partition board, so that most of the cryopreservation tube is still inside the cryopreservation tank after the sealing cover is opened. And the rotation of the heat preservation partition board can drive the sliding rod below the limiting ring to move together. When the sliding rod moves to the position of the lifting convex block on the guiding ring, the sliding rod will be lifted by the lifting convex block, so as to lift the cryopreservation tube above and raise it from the placement groove, which is convenient for the staff to take and avoid the problem of easy frostbite when reaching deep to take.

[0017] 2. After the sealing cover of the utility model is opened, the driving gear can be lifted by holding the hand wheel, and the rotating rod is stuck in the limiting groove of the limiting block. At this time, the driving gear meshes with the gear ring, so as to conveniently drive the heat preservation partition board to rotate by rotating the hand wheel through the hand wheel, avoiding the situation that the operator needs to directly contact the heat preservation partition board when rotating the heat preservation partition board and ensuring the safety of the operation. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] The drawings described herein are used to provide a further understanding of the utility model and form a part of this application:

[0019] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0020] Figure 2 It is a schematic diagram of the internal structure of the cryopreservation tank of the utility model;

[0021] Figure 3 It is a schematic diagram of the gear ring part of the utility model;

[0022] Figure 4 It is a schematic diagram of the structure of the limiting block of the utility model.

[0023] In the figure: 1, cryopreservation tank; 2, sealing cover; 3, lifting mechanism; 31, heat preservation partition board; 32, cryopreservation tube; 33, connecting rod; 34, limiting ring; 35, sliding rod; 351, bracket; 352, guide wheel; 36, guiding ring; 361, lifting convex block; 37, gear ring; 38, driving gear; 380, support; 381, hinge rod; 382, rotating rod; 383, hand wheel; 384, limiting block; 3841, limiting groove; 3842, sliding groove; 3843, clamping block; 3844, spring. DETAILED DESCRIPTION OF THE INVENTION

[0024] The following will clearly and completely describe the technical solutions in the embodiments of the present utility model with reference to the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present utility model without making creative efforts shall fall within the protection scope of the present utility model.

[0025] Embodiment 1

[0026] An immunocyte cryopreservation device, as Figure 1 , Figure 2 shown, includes a cryopreservation tank 1. A sealing cover 2 is hinged to the top of the cryopreservation tank 1. A lifting mechanism 3 is arranged inside the cryopreservation tank 1. The lifting mechanism 3 includes a heat preservation partition 31. The heat preservation partition 31 is rotatably connected to the top of the inner wall of the cryopreservation tank 1. Multiple placement slots are formed in the top of the heat preservation partition 31, and the placement slots are annularly distributed. The placement slots are used to place cryopreservation tubes 32. A guide ring 36 is connected to the bottom of the inner wall of the cryopreservation tank 1. A lifting bump 361 is arranged on the top of the guide ring 36. The bottom of the heat preservation partition 31 is connected with a limiting ring 34 through a connecting rod 33. A sliding rod 35 is slidably connected to the inner wall of the limiting ring 34 corresponding to each placement slot.

[0027] In this embodiment, by placing the cryopreservation tube 32 for storing immunocytes in the placement slots on the top of the heat preservation partition 31, most of the cryopreservation tubes 32 are still inside the cryopreservation tank 1 after the sealing cover 2 is opened, so as to reduce the influence of the external temperature difference on the immunocytes in the cryopreservation tube 32 when the cryopreservation tube 32 is taken out. And the rotation of the heat preservation partition 31 can drive the sliding rod 35 below the limiting ring 34 to move together. When the sliding rod 35 moves to the position of the lifting bump 361 on the guide ring 36, the sliding rod 35 will be lifted by the lifting bump 361, so as to lift the upper cryopreservation tube 32 and raise it from the placement slot, which is convenient for the staff to take and avoid the problem of easy frostbite when reaching deep to take.

[0028] Embodiment 2

[0029] As Figure 2 shown, no placement slot is opened at the position of the heat preservation partition 31 above the lifting bump 361 to stagger the cryopreservation tubes 32. Buffer pads are arranged on the tops of the sliding rods 35. The buffer pads are used to protect the cryopreservation tubes 32. Guide wheels 352 are connected to the bottoms of the sliding rods 35, and the guide wheels 352 are in rolling connection with the top of the guide ring 36.

[0030] In this embodiment, by arranging the brackets 351 with buffer pads, the cryopreservation tubes 32 can be protected. By arranging the guide wheels 352 at the bottoms of the sliding rods 35, the resistance when the sliding rods 35 move above the guide ring 36 can be effectively reduced.

[0031] Example 3

[0032] As Figure 3 、 Figure 4 shown, a gear ring 37 is connected to the top of the heat preservation partition plate 31. The outer wall of the gear ring 37 is meshed and connected with a driving gear 38. A support 380 is connected to the outer wall of the cryogenic storage tank 1 at a position below the driving gear 38. A hinged rod 381 is hinged to the inner wall of the support 380. The top of the hinged rod 381 is rotationally connected with a rotating rod 382, and the rotating rod 382 is connected with the driving gear 38. A hand wheel 383 is connected to the top of the driving gear 38. A limiting block 384 is arranged at the position of the outer wall of the cryogenic storage tank 1 corresponding to the rotating rod 382. The inner wall of the limiting block 384 is provided with a limiting groove 3841. Two sides of the inner wall of the limiting groove 3841 are respectively provided with sliding grooves 3842, and a clamping block 3843 is slidably connected to the inner wall of the sliding groove 3842. Springs 3844 are connected between the inner wall of the sliding groove 3842 and the clamping block 3843.

[0033] In this embodiment, after the sealing cover 2 is opened, the driving gear 38 can be lifted by holding the hand wheel 383. The rotating rod 382 is stuck in the limiting groove 3841 of the limiting block 384. At this time, the driving gear 38 is meshed with the gear ring 37, so as to facilitate driving the driving gear 38 to rotate by rotating the hand wheel 383 through the hand wheel 383, and driving the heat preservation partition plate 31 to rotate by meshing with the gear ring 37, avoiding the situation that the operator needs to directly contact the heat preservation partition plate 31 when rotating the heat preservation partition plate 31, ensuring the safety of the operation, and the tension of the spring 3844 pushes the clamping block 3843 to limit the rotating rod 382, which also ensures the stability of the driving gear 38 when rotating.

[0034] When the immunocyte cryogenic storage device of the present utility model is in use, after the sealing cover 2 is opened, the driving gear 38 can be lifted by holding the hand wheel 383. The rotating rod 382 is stuck in the limiting groove 3841 of the limiting block 384. At this time, the driving gear 38 is meshed with the gear ring 37, so as to facilitate driving the driving gear 38 to rotate by rotating the hand wheel 383 through the hand wheel 383, and driving the heat preservation partition plate 31 to rotate by meshing with the gear ring 37, avoiding the situation that the operator needs to directly contact the heat preservation partition plate 31 when rotating the heat preservation partition plate 31, and the tension of the spring 3844 pushes the clamping block 3843 to limit the rotating rod 382, which also ensures the stability of the driving gear 38 when rotating. By rotating the heat preservation partition plate 31, the sliding rod 35 below the limiting ring 34 can be driven to move together. When the sliding rod 35 moves to the position of the lifting convex block 361 on the guide ring 36, the sliding rod 35 will be lifted by the lifting convex block 361, so as to lift the upper cryogenic tube 32 and raise it from the placement groove, facilitating the staff to take it.

[0035] It should be noted that in this text, relational terms such as first and second are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the terms "comprising", "including" or any other variant thereof are intended to cover non-exclusive inclusion, such that a process, method, article or device comprising a series of elements not only includes those elements but also includes other elements not expressly listed, or elements inherent to such process, method, article or device.

[0036] Although embodiments of the present invention have been shown and described, those of ordinary skill in the art can understand that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of the present invention. The scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An immunocyte cryopreservation device, comprising a cryopreservation tank (1), characterized in that: A sealing cover (2) is hinged to the top of the cryogenic storage tank (1), and a lifting mechanism (3) is arranged inside the cryogenic storage tank (1). The lifting mechanism (3) includes a heat-insulating partition board (31). The heat-insulating partition board (31) is rotatably connected to the top of the inner wall of the cryogenic storage tank (1). A plurality of placing grooves are formed in the top of the heat-insulating partition board (31), and the placing grooves are annularly distributed. The placing grooves are used for placing cryogenic tubes (32). A guide ring (36) is connected to the bottom of the inner wall of the cryogenic storage tank (1). A lifting bump (361) is arranged on the top of the guide ring (36). The bottom of the heat-insulating partition board (31) is connected with a limiting ring (34) through a connecting rod (33). Slide rods (35) are slidably connected to the positions of the inner wall of the limiting ring (34) corresponding to each placing groove.

2. The cryopreservation device for immune cells according to claim 1, characterized in that: The position of the heat-insulating partition board (31) above the lifting bump (361) is not provided with a placing groove for staggering the cryogenic tubes (32).

3. An immunocyte cryopreservation device according to claim 1, characterized in that: Buffers are arranged on the brackets (351) connected to the tops of the slide rods (35) for protecting the cryogenic tubes (32).

4. The cryopreservation device for immune cells according to claim 3, characterized in that: Guide wheels (352) are connected to the bottoms of the slide rods (35), and the guide wheels (352) are in rolling connection with the top of the guide ring (36).

5. The cryopreservation device for immune cells according to claim 1, wherein: A gear ring (37) is connected to the top of the heat-insulating partition board (31). A driving gear (38) is meshed with the outer wall of the gear ring (37). A support (380) is connected to the position of the outer wall of the cryogenic storage tank (1) below the driving gear (38). A hinge rod (381) is hinged to the inner wall of the support (380). A rotating rod (382) is rotatably connected to the top of the hinge rod (381), and the rotating rod (382) is connected with the driving gear (38).

6. The cryopreservation device for immune cells according to claim 5, characterized in that: A hand wheel (383) is connected to the top of the driving gear (38). A limiting block (384) is arranged at the position of the outer wall of the cryogenic storage tank (1) corresponding to the rotating rod (382).

7. The cryopreservation device for immune cells according to claim 6, characterized in that: The limiting block (384) is provided with a limiting groove (3841) in its inner wall. Chute grooves (3842) are respectively formed on both sides of the inner wall of the limiting groove (3841), and a clamping block (3843) is slidably connected to the inner wall of the chute groove (3842). Springs (3844) are respectively connected between the inner wall of the chute groove (3842) and the clamping block (3843).

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