Drying treatment device for liflozin intermediates

The apparatus addresses uneven heating and vapor condensation in SGLT2 intermediate drying by using U-shaped heating elements and vents, ensuring uniform heating and efficient multi-batch processing.

CN223106549UActive Publication Date: 2025-07-15HENGSHENG DEKANG (NANJING) PHARM TECH CO LTD
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Patent Information

Application Number
CN202421999495.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-08-19
Publication Date
2025-07-15
Estimated Expiration
2034-08-19

AI Technical Summary

Technical Problem

When existing chemical enterprises dry the lienin intermediate, there are problems such as uneven heating, water vapor condensation affecting the effect and being unable to process multiple batches at the same time, resulting in poor drying effect and low working efficiency.

Method used

A device including a drying box box and box door is designed, using a U-shaped heating pipe and exhaust pipe structure to ensure uniform heat distribution and discharge water vapor through the exhaust pipe. A limit block and groove structure are set to facilitate the connection and separation of box doors, and support multiple batch processing.

Benefits of technology

It realizes uniform heating and drying of lienin intermediates, prevents water vapor condensation, improves drying effect and working efficiency, and supports multiple batch processing.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a liflozin intermediate drying treatment device which comprises a drying box body part and a drying box door part, the drying box door part is arranged on the right side of the drying box body part, the drying box body part comprises a box body shell, and the drying box door part is used for loading liflozin intermediates. The whole device can be sealed, and the drying box body part is used for drying the liflozin intermediates; a plurality of exhaust pipes are fixedly connected to the left side of the box body shell and outwards penetrate through the box body shell, a plurality of heating plates are fixedly connected to the interior of the box body shell, heating pipes are fixedly connected to the interiors of the heating plates, the heating pipes are U-shaped, and the exhaust pipes are used for exhausting water vapor generated when the liflozin intermediates are dried; and the heating pipe is U-shaped, so that heat on the heating plate can be uniformly distributed, so that the liflozin intermediates are uniformly heated, and the situation that part of the liflozin intermediates cannot be dried, and the drying effect on the liflozin intermediates is affected is prevented.
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Description

Technical Field

[0001] The utility model relates to the field of drying treatment devices for pharmaceutical intermediates, and particularly relates to a drying treatment device for SGLT2 inhibitor intermediates. Background Art

[0002] The production of drugs requires a large number of special chemicals. Most of these chemicals were originally produced by the pharmaceutical industry itself. However, with the deepening of social division of labor and the progress of production technology, the pharmaceutical industry has transferred some pharmaceutical intermediates to chemical enterprises for production. So-called pharmaceutical intermediates are actually some chemical raw materials or chemical products used in the drug synthesis process. Such chemical products do not require a drug production license and can be produced in ordinary chemical factories. As long as they reach a certain level, they can be used for drug synthesis; SGLT2 inhibitors refer to a class of novel oral hypoglycemic drugs. These drugs lower blood glucose levels by inhibiting the reabsorption of glucose by the kidneys, reducing the renal threshold of glucose, and promoting the excretion of urinary glucose.

[0003] At present, when chemical enterprises dry SGLT2 inhibitor intermediates, the heating device is usually in a fixed place and cannot uniformly heat and dry the SGLT2 inhibitor intermediates. Sometimes, the water vapor generated during drying will condense and fall into the SGLT2 inhibitor intermediates, affecting the drying effect, and multiple batches of SGLT2 inhibitor intermediates cannot be dried simultaneously, affecting work efficiency. Summary of the Utility Model

[0004] The purpose of the utility model is to provide a drying treatment device for SGLT2 inhibitor intermediates, which solves the problems of poor drying effect and low work efficiency in the prior art.

[0005] To achieve the above purpose, the utility model adopts the following technical scheme: a drying treatment device for SGLT2 inhibitor intermediates, including a drying box body part and a drying box door part. The drying box door part is arranged on the right side of the drying box body part. The drying box body part includes a box body shell; a plurality of exhaust pipes are fixedly connected to the left side of the box body shell, and the exhaust pipes penetrate through the box body shell outward. A plurality of heating plates are fixedly connected inside the box body shell, and heating pipes are fixedly connected inside the heating plates. The heating pipes are in a U shape.

[0006] As a further description of the above technical scheme: a plurality of jacks are arranged on the right side of the box body shell, and the jacks are arranged above the heating plates. A first groove and a second groove are arranged on the right side of the box body shell, and the second groove is arranged behind the first groove.

[0007] As a further description of the above technical scheme: a spring is fixedly connected inside the second groove, and the other end of the spring is fixedly connected to a moving plate.

[0008] As a further description of the above technical solution: a first limiting block is fixedly connected to the other side of the moving plate, and the first limiting block penetrates through the second groove and the first groove.

[0009] As a further description of the above technical solution: the drying oven door part includes a connecting plate, and a handle is fixedly connected to the right side of the connecting plate.

[0010] As a further description of the above technical solution: a plurality of fixing plates are fixedly connected to the left side of the connecting plate, and a third groove is provided on the fixing plates.

[0011] As a further description of the above technical solution: a second limiting block is fixedly connected to the connecting plate, and a limiting hole is provided on the second limiting block.

[0012] The present utility model has the following beneficial effects:

[0013] 1. Compared with the prior art, in this drying and processing device for sitagliptin intermediates, by arranging a heating plate, a U-shaped heating tube, a third groove, and an exhaust pipe, the sitagliptin intermediates are evenly placed in the third groove, so that the heat on the heating plate can be evenly distributed, uniformly heating the sitagliptin intermediates, and the exhaust pipe can timely discharge the water vapor generated during the drying process from the drying oven, preventing the condensed water vapor from falling into the sitagliptin intermediates, thus ensuring the drying effect;

[0014] 2. Compared with the prior art, in this drying and processing device for sitagliptin intermediates, by arranging a plurality of heating plates and fixing plates, multiple batches of sitagliptin intermediates can be dried simultaneously, improving the working efficiency;

[0015] 3. Compared with the prior art, in this drying and processing device for sitagliptin intermediates, by arranging a second limiting block, a limiting hole, a first limiting block, and a first groove, it is convenient to connect or separate the drying oven door part from the drying oven body part.

[0016] The additional aspects and advantages of the present utility model will be partially given in the following description, partially will become obvious from the following description, or be understood through the practice of the present utility model. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] The following further illustrates the present utility model in conjunction with the drawings and embodiments;

[0018] Figure 1 is the overall structural schematic diagram of the present utility model.

[0019] Figure 2 is the internal structural schematic diagram of the box body shell of the present utility model.

[0020] Figure 3 It is a schematic structural diagram of the door part of the drying oven of the present utility model.

[0021] Figure 4 It is a schematic structural diagram of the box body part of the drying oven of the present utility model.

[0022] Figure 5 It is a schematic structural diagram of part A of the present utility model.

[0023] Figure 6 It is a schematic structural diagram of the connecting plate of the present utility model.

[0024] Figure 7 It is a schematic internal structure diagram of the heating plate of the present utility model.

[0025] Legend Explanation:

[0026] 1. Box body part of the drying oven; 101. Exhaust pipe; 102. Heating plate; 103. Box body shell; 104. Jack; 105. First groove; 106. First limit block; 107. Moving plate; 108. Spring; 109. Second groove; 110. Heating tube; 2. Door part of the drying oven; 201. Fixed plate; 202. Third groove; 203. Connecting plate; 204. Handle; 205. Second limit block; 206. Limit hole. Specific Embodiment

[0027] This part will describe in detail the specific embodiments of the present utility model. The preferred embodiments of the present utility model are shown in the drawings. The function of the drawings is to supplement the description in the text part of the specification, enabling people to intuitively and vividly understand each technical feature and the overall technical solution of the present utility model, but it should not be construed as a limitation on the protection scope of the present utility model.

[0028] Referring to Figure 1-7 , an embodiment provided by the present utility model, a drying and processing device for a canagliflozin intermediate, includes a box body part 1 of the drying oven and a door part 2 of the drying oven. It is characterized in that the door part 2 of the drying oven is arranged on the right side of the box body part 1 of the drying oven. The box body part 1 of the drying oven includes a box body shell 103. The door part 2 of the drying oven is used to load the canagliflozin intermediate and can seal the whole device to prevent heat loss. The box body part 1 of the drying oven is used to dry the canagliflozin intermediate;

[0029] On the left side of the box body shell 103, several exhaust pipes 101 are fixedly connected. The exhaust pipes 101 penetrate the box body shell 103 outward. Inside the box body shell 103, several heating plates 102 are fixedly connected. Inside the heating plates 102, heating tubes 110 are fixedly connected. The heating tubes 110 are U-shaped. The exhaust pipes 101 are used to discharge the water vapor generated during the drying of the canagliflozin intermediates. The U-shaped heating tubes 110 can make the heat on the heating plates 102 evenly distributed, so as to uniformly heat the canagliflozin intermediates and prevent some canagliflozin intermediates from not being dried, affecting the drying effect of the canagliflozin intermediates.

[0030] On the right side of the box body shell 103, several jacks 104 are provided. The jacks 104 are arranged above the heating plates 102. On the right side of the box body shell 103, a first groove 105 and a second groove 109 are provided. The second groove 109 is arranged behind the first groove 105.

[0031] Inside the second groove 109, a spring 108 is fixedly connected. The other end of the spring 108 is fixedly connected with a moving plate 107. By pulling the moving plate 107, the spring 108 can be squeezed.

[0032] On the other side of the moving plate 107, a first limiting block 106 is fixedly connected. The first limiting block 106 penetrates the second groove 109 and the first groove 105. When pulling the moving plate 107 to squeeze the spring 108, the part of the first limiting block 106 in the first groove 105 will be retracted from the first groove 105 into the second groove 109.

[0033] The drying oven door part 2 includes a connecting plate 203. On the right side of the connecting plate 203, a handle 204 is fixedly connected. By pulling the handle 204, the entire drying oven door part 2 can be moved to connect or separate the drying oven door part 2 from the drying oven body part 1.

[0034] On the left side of the connecting plate 203, several fixing plates 201 are fixedly connected. On the fixing plates 201, third grooves 202 are provided. The fixing plates 201 correspond to the jacks 104. The third grooves 202 are used to place the canagliflozin intermediates. After inserting the fixing plates 201 into the jacks 104, the preliminary connection between the drying oven door part 2 and the drying oven body part 1 is completed.

[0035] A second limiting block 205 is fixedly connected to the connecting plate 203. A limiting hole 206 is provided on the second limiting block 205. The second limiting block 205 corresponds to the first groove 105, and the second limiting hole 206 corresponds to the first limiting block 106. After inserting the second limiting block 205 into the first groove 105, release the moving plate 107. Under the action of the spring 108, move the first limiting block 106 from the second groove 109 into the first groove 105 and insert it into the second limiting hole 206 to complete the stable connection between the drying oven door part 2 and the drying oven body part 1.

[0036] Working principle: When the device is in use, first evenly place the sodium-glucose cotransporter 2 (SGLT2) inhibitor intermediate in the third groove 202. Then pull the handle 204 to insert the fixing plate 201 into the jack 104 to complete the preliminary connection between the drying oven door part 2 and the drying oven body part 1. Then pull the moving plate 107 to squeeze the spring 108, driving the part of the first limiting block 106 in the first groove 105 to retract from the first groove 105 into the second groove 109. Then insert the second limiting block 205 into the first groove 105. At this time, release the moving plate 107. Under the action of the spring 108, move the first limiting block 106 from the second groove 109 into the first groove 105 and insert it into the second limiting hole 206 to complete the stable connection between the drying oven door part 2 and the drying oven body part 1. At this time, the fixing plate 201 contacts the heating plate 102, and start the heating tube 110 to dry the SGLT2 inhibitor intermediate. The heating tube 110 is in a U shape, which can make the heat on the heating plate 102 evenly distributed, so as to evenly heat the SGLT2 inhibitor intermediate and prevent some SGLT2 inhibitor intermediates from not being dried, affecting the drying effect of the SGLT2 inhibitor intermediate.

[0037] The above has described the embodiments of the present invention in detail with reference to the accompanying drawings. However, the present invention is not limited to the above embodiments. Within the scope of knowledge possessed by those of ordinary skill in the art in the said technical field, various changes can be made without departing from the gist of the present invention.

Claims

1. A drying treatment device for a canagliflozin intermediate, comprising a drying box body part (1) and a drying box door part (2), characterized in that, The door part (2) of the drying oven is arranged on the right side of the body part (1) of the drying oven, and the body part (1) of the drying oven includes a body shell (103); A plurality of exhaust pipes (101) are fixedly connected to the left side of the body shell (103), the exhaust pipes (101) penetrate through the body shell (103) outward, a plurality of heating plates (102) are fixedly connected inside the body shell (103), a heating pipe (110) is fixedly connected inside the heating plate (102), and the heating pipe (110) is U-shaped; The door part (2) of the drying oven includes a connecting plate (203), a handle (204) is fixedly connected to the right side of the connecting plate (203), a plurality of fixing plates (201) are fixedly connected to the left side of the connecting plate (203), and a third groove (202) is arranged on the fixing plate (201).

2. The drying treatment device for a canagliflozin intermediate according to claim 1, characterized in that, A plurality of jacks (104) are arranged on the right side of the body shell (103), the jacks (104) are arranged above the heating plate (102), a first groove (105) and a second groove (109) are arranged on the right side of the body shell (103), and the second groove (109) is arranged behind the first groove (105).

3. The drying treatment device for a canagliflozin intermediate according to claim 2, wherein, A spring (108) is fixedly connected inside the second groove (109), and the other end of the spring (108) is fixedly connected to a moving plate (107).

4. The drying treatment device for a canagliflozin intermediate according to claim 3, characterized in that, The other side of the moving plate (107) is fixedly connected to a first limiting block (106), and the first limiting block (106) penetrates through the second groove (109) and the first groove (105).

5. The drying and processing device for a canagliflozin intermediate according to claim 1, wherein A second limiting block (205) is fixedly connected to the connecting plate (203), and a limiting hole (206) is arranged on the second limiting block (205).