Particle analysis device adopting microscopic counting method

Abstract

The utility model discloses a microscopic counting method particle analysis device, which relates to the technical field of particle analysis devices, and comprises a platform cover plate, an electric platform, a first support frame, a light path module and a light source module, the output end of the electric platform is connected with the platform cover plate and used for controlling the platform cover plate to move in the first direction and / or the second direction, the first supporting frame is arranged on one side of the platform cover plate, and the middle of the side, facing the tray, of the first supporting frame is connected with a focusing motor. The light path module is connected with the output end of the focusing motor and used for being matched with the focusing motor to conduct focusing action, the light source module is arranged on one side of the light path module and used for providing and transmitting a light source, the structure of the device is simplified, the overall stability of the device is improved, and the service life of the device is prolonged.

Description

Technical Field

[0001] The utility model relates to the technical field of particle analysis devices, and particularly to a particle analysis device for microscopic counting method. Background Technique

[0002] As one of the basic methods for detecting insoluble particles in industries such as medicine and medical devices, the microscopic counting method is particularly suitable for some samples that are difficult to detect by the light obscuration method, such as dosage forms like emulsions, liposomes, suspensions, etc., and the microscopic counting method has an irreplaceable role.

[0003] The basic principle of the microscopic counting method is as follows: Under a microscope, a sufficient field area of the sample is collected, and the particles in the image within the field area are counted. This method requires repeatedly adjusting the focus position of the field of view, and also requires repeatedly adjusting the field of view range in the XY directions of the sample. However, this method is relatively cumbersome in operation and time-consuming in detection.

[0004] An optical microscope equipped with an electric stage and an electric focal plane adjustment device is a simple and easy-to-implement way to realize an automated microscopic counting method. However, this method has defects:

[0005] 1. The electric stage is installed on the focusing cantilever mechanism, and the electric stage moves up and down driven by the lifting mechanism to achieve focusing. However, this cantilever structure has defects of complex structure and insufficient structural stability. Since the support force is provided by the unilateral structure of the cantilever, this structure is prone to vertical angle inclination, resulting in a decrease in detection accuracy.

[0006] 2. Since the cantilever structure drives the stage to move vertically to achieve focusing, the entire focusing mechanism additionally bears the weight of the electric stage, which poses a challenge to improving the movement speed of the focusing mechanism, and the service life of the entire mechanism will also be affected by the above factors.

[0007] Therefore, it is necessary to design a particle analysis device for microscopic counting method based on a new structure. Content of the Utility Model

[0008] The purpose of the utility model is to provide a particle analysis device for microscopic counting method in view of the existing technical defects, so as to solve the problems raised in the above background technique.

[0009] To solve the above technical problems, the present utility model provides the following technical solution: A particle analysis device using microscopic counting method, comprising a platform cover plate, an electric platform, a first support frame, an optical path module, and a light source module. A tray is installed on the platform cover plate, and a sample to be measured is placed in the tray. The output end of the electric platform is connected to the platform cover plate, and is used to control the movement of the platform cover plate in the first direction and / or the second direction. The first support frame is arranged on one side of the platform cover plate, and a focusing motor is connected to the middle of the side of the first support frame facing the tray. The optical path module is connected to the output end of the focusing motor and is used to cooperate with the focusing motor to perform a focusing action. The light source module is arranged on one side of the optical path module and is used for providing and transmitting light sources, avoiding a cantilever structure, and improving the stability and service life of the device structure.

[0010] The present utility model further explains that an image acquisition module is arranged on the top of the optical path module. The image acquisition module is used to acquire images. A third support frame is fixedly installed below the image acquisition module, and the bottom of the third support frame is fixedly connected to a lens barrel, providing an optical path channel for imaging.

[0011] The present utility model further explains that the light source module includes a light source, a lighting port, and a first lighting box. The top of the first lighting box is connected to the light source through the lighting port.

[0012] The present utility model further explains that the optical path module includes an objective lens, a second lighting box, and a lens adapter ring. A reflecting part is installed inside the second lighting box. The top of the objective lens is connected to one end of the lens adapter ring, and the other end of the lens adapter ring is fixedly connected to the output end of the focusing motor.

[0013] The present utility model further explains that a dust-proof cover is sleeved outside the objective lens, and the dust-proof cover is fixedly connected to the bottom of the second lighting box. The dust-proof cover plays a role in dust-proofing the objective lens. The dust-proof cover and the lens adapter ring are arranged in a penetrating manner to facilitate the up and down movement of the lens adapter ring.

[0014] The present utility model further explains that the particle analysis device using microscopic counting method further includes a power supply module and a main control module. The power supply module is connected to the main control module and the light source module, and the electric platform and the focusing motor are both connected to the main control module.

[0015] The present utility model further explains that a bottom plate is installed at the bottom of the electric platform, playing a role in supporting the connecting components.

[0016] Compared with the prior art, the beneficial effects achieved by the present utility model are:

[0017] By providing an electric platform and a focusing motor, the structure of the particle analysis device is simplified. The electric platform is installed on the bottom plate, avoiding the cantilever structure and enhancing the stability and lifespan of the device structure. By changing the method of adjusting the height of the objective lens to achieve focusing, the weight of the focal length adjustment mechanism is reduced, and the speed of the focusing movement is also increased. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] The drawings are used to provide a further understanding of the present invention and form a part of the specification. Together with the embodiments of the present invention, they are used to explain the present invention, but do not constitute a limitation to the present invention. In the drawings:

[0019] Figure 1 is a front view schematic diagram of the overall structure of the present invention;

[0020] Figure 2 is a rear view schematic diagram of the overall structure of the present invention;

[0021] Figure 3 is a disassembled schematic diagram of the overall structure of the present invention;

[0022] In the figures: 1, platform cover plate; 2, electric platform; 21, first-direction moving part; 22, second-direction moving part; 3, tray; 4, first support frame; 5, second support frame; 6, focusing motor; 7, objective lens; 8, light source module; 81, light source; 82, illumination port; 83, first illumination box; 9, dust-proof cover; 10, second illumination box; 11, reflecting part; 12, lens barrel; 13, image acquisition module; 14, third support frame; 15, bottom plate; 16, power supply module; 17, main control module; 18, lens adapter ring. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0023] The following provides a non-limiting and detailed description of the technical solution of the present invention in combination with the preferred embodiments and their accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts fall within the scope of protection of the present invention.

[0024] Please refer to Figures 1-3 , the present invention provides a technical solution: a particle analysis device using microscopic counting method, including a platform cover plate 1, an electric platform 2, an optical path module, a focusing motor 6, a light source module 8, an image acquisition module 13, a power supply module 16, and a main control module 17.

[0025] Among them, a tray 3 is embedded on the upper surface of the platform cover plate 1, and a sample to be tested is placed in the tray 3. The sample contains particles and is used for subsequent sample detection procedures;

[0026] A bottom plate 15 is fixedly installed at the bottom of the electric platform 2 to support the connecting components. The electric platform 2 is composed of a first-direction moving part 21 and a second-direction moving part 22 arranged in sequence from bottom to top. The first-direction moving part 21 and the second-direction moving part 22 are respectively moving driving components in the first direction and the second direction. Generally, on the plane shown as the X and Y directions, the bottom of the first-direction moving part 21 is fixed to the bottom plate 15, the output end of the first-direction moving part 21 is fixedly connected to the bottom of the second-direction moving part 22, and the output end of the second-direction moving part 22 is connected to the platform cover plate 1; Figure 1 On the plane shown, in the X and Y directions, the bottom of the first-direction moving part 21 is fixed to the bottom plate 15, the output end of the first-direction moving part 21 is fixedly connected to the bottom of the second-direction moving part 22, and the output end of the second-direction moving part 22 is connected to the platform cover plate 1;

[0027] Compared with the cantilever structure, the electric platform 2 bears the platform cover plate 1 and realizes its movement in two directions to achieve sampling in different areas of the sample, simplifies the structure, and at the same time eliminates the cantilever structure, improving the overall stability and service life of the device.

[0028] A first support frame 4 is arranged on one side of the platform cover plate 1. An optical support block is fixedly connected between the bottom of the first support frame 4 and the bottom plate 15. A second support frame 5 is fixedly connected to the side of the first support frame 4 facing the platform cover plate 1. A focusing motor 6 is connected to the side of the second support frame 5 facing the platform cover plate 1. The output end of the focusing motor 6 is connected to the optical path module;

[0029] The optical path module includes an objective lens 7, a second illumination box 10, and a lens adapter ring 18. A reflecting part 11 is fixedly installed inside the second illumination box 10. The top of the objective lens 7 is fixedly connected to one end of the lens adapter ring 18. The other end of the lens adapter ring 18 is fixedly connected to the output end of the focusing motor 6. The output end of the focusing motor 6 is set for movement in the third direction. Referring to the Z direction shown, by starting the focusing motor 6, its output end drives the lens adapter ring 18 and the objective lens 7 to move in the Z direction, and the focusing action is realized through the up and down movement with a fine step distance. Figure 1 The image acquisition module 13 is used to acquire images. The image acquisition module 13 can be set as a camera. A third support frame 14 is fixedly installed below the image acquisition module 13. The third support frame 14 can be a camera adapter tube. The bottom of the third support frame 14 is fixedly connected to a lens barrel 12. The lens barrel 12 provides an optical path channel for imaging. The lens barrel 12 is fixedly connected to the side of the top of the first support frame 4 facing the platform cover plate 1. The lower surface of the lens barrel 12 is fixedly connected to the second illumination box 10. A dust cover 9 is fixedly connected to the bottom of the second illumination box 10. The dust cover 9 is sleeved outside the objective lens 7 to play a role in dust prevention for the objective lens 7. The dust cover 9 and the lens adapter ring 18 are arranged in a penetrating manner to facilitate the up and down movement of the lens adapter ring 18.

[0030] The image acquisition module 13 is used to acquire images. The image acquisition module 13 can be set as a camera. A third support frame 14 is fixedly installed below the image acquisition module 13. The third support frame 14 can be a camera adapter tube. The bottom of the third support frame 14 is fixedly connected to a lens barrel 12. The lens barrel 12 provides an optical path channel for imaging. The lens barrel 12 is fixedly connected to the side of the top of the first support frame 4 facing the platform cover plate 1. The lower surface of the lens barrel 12 is fixedly connected to the second illumination box 10. A dust cover 9 is fixedly connected to the bottom of the second illumination box 10. The dust cover 9 is sleeved outside the objective lens 7 to play a role in dust prevention for the objective lens 7. The dust cover 9 and the lens adapter ring 18 are arranged in a penetrating manner to facilitate the up and down movement of the lens adapter ring 18.

[0031] The light source module 8 is fixedly arranged on one side of the second lighting box 10. The light source module 8 includes a light source 81, a lighting port 82, and a first lighting box 83. The second lighting box 10 is fixedly connected to the first lighting box 83 and is internally communicated. The top of the first lighting box 83 is connected to the light source 81 through the lighting port 82 to provide and transmit the light source, and is used to cooperate with the image acquisition module 13 and the optical path module to acquire clear images.

[0032] The power supply module 16 and the main control module 17 are respectively installed on the other surface of the bottom plate 15. The power supply module 16 is connected to the main control module 17 and the light source module 8 to provide power supply for them. The electric platform 2 and the focusing motor 6 are both connected to the main control module 17, and their movements are controlled by the main control module 17. The main control module 17 and the image acquisition module 13 are connected to a computer. The computer controls the movement of the electric platform 2 by controlling the main control module 17 to achieve sampling of different sample areas. At the same time, by adjusting the focusing motor 6, the focusing of the image is achieved. After the focal length of the area to be sampled is adjusted, the computer controls the image acquisition module 13 to perform image acquisition, and transmits the acquired image to the computer for analysis and processing to obtain particle information.

[0033] In this embodiment, the installation of the electric platform 2, the optical path module, the focusing motor 6, the light source module 8, the image acquisition module 13, the power supply module 16, and the main control module 17 at their corresponding positions on the bottom plate 15 is completed in advance. The power supply module 16 is powered on. The platform cover 1 with the sample to be measured is installed on the electric platform 2. The computer controls the main control module 17, and then controls the electric platform 2 to move in the first direction and / or the second direction to achieve sampling in different sample areas. At the same time, by adjusting the focusing motor 6, the focusing of the image is achieved. The optical path module and the power supply module 16 are used to assist the image acquisition module 13 to obtain particle information and complete subsequent particle analysis.

[0034] In the description of the present invention, it should be understood that the orientation or positional relationship indicated by the terms "upper", "lower", "front", "rear", "left", "right", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present invention, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation of the present invention.

[0035] Finally, it should be pointed out that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit them. Although the present invention has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that they can still modify the technical solutions described in the foregoing embodiments, or perform equivalent replacements for some of the technical features. These modifications or replacements do not make the essence of the corresponding technical solutions deviate from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. A particle analysis device using a microscopic counting method, characterized in that: Comprising: A platform cover plate (1), on which a tray (3) is installed, and a sample to be measured is placed in the tray (3); An electric platform (2), the output end of the electric platform (2) is connected to the platform cover plate (1), and is used to control the platform cover plate (1) to move in the first direction and / or the second direction; A first support frame (4), the first support frame (4) is arranged on one side of the platform cover plate (1), and a focusing motor (6) is connected to the middle part of the side of the first support frame (4) facing the tray (3); An optical path module, connected to the output end of the focusing motor (6), and is used to cooperate with the focusing motor (6) to perform a focusing action; A light source module (8), arranged on one side of the optical path module, and is used for providing and transmitting light sources.

2. The particle analysis device using the microscopic counting method according to claim 1, characterized in that: An image acquisition module (13) is arranged on the top of the optical path module, and the image acquisition module (13) is used for acquiring images; A third support frame (14) is fixedly installed below the image acquisition module (13), and the bottom of the third support frame (14) is fixedly connected to a lens barrel (12).

3. The particle analysis device using the microscopic counting method according to claim 1, wherein: The light source module (8) includes a light source (81), a lighting port (82), and a first lighting box (83), and the top of the first lighting box (83) is connected to the light source (81) through the lighting port (82).

4. The particle analysis device using the microscopic counting method according to claim 3, characterized in that: The optical path module includes an objective lens (7), a second lighting box (10), and a lens adapter ring (18), and a reflecting part (11) is installed inside the second lighting box (10); The top of the objective lens (7) is connected to one end of the lens adapter ring (18), and the other end of the lens adapter ring (18) is fixedly connected to the output end of the focusing motor (6).

5. The particle analysis device using a microscopic counting method according to claim 4, characterized in that: A dust cover (9) is sleeved outside the objective lens (7), and the dust cover (9) is fixedly connected to the bottom of the second lighting box (10).

6. The particle analysis device using a microscopic counting method according to claim 4, characterized in that: It further includes a power supply module (16) and a main control module (17), the power supply module (16) is connected to the main control module (17) and the light source module (8), and the electric platform (2) and the focusing motor (6) are both connected to the main control module (17).

7. A particle analysis device using a microscopic counting method according to any one of claims 1-6, characterized in that: A bottom plate (15) is installed at the bottom of the electric platform (2).

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