Brucella antibody detection box

By designing a Brucella antibody detection box, the adjustable lighting angle and magnet system positioning the bearing disk is used to solve the problem of close observation when there is insufficient light, and safe and efficient post-detection disinfection is achieved through the disinfectant spraying assembly, reducing the risk of infection.

CN223166756UActive Publication Date: 2025-07-29THE SECOND AFFILIATED HOSPITAL OF LUOHE MEDICAL COLLEGE
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Patent Information

Application Number
CN202422060793.8
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-08-24
Publication Date
2025-07-29
Estimated Expiration
2034-08-24

AI Technical Summary

Technical Problem

The existing Brucella detection device is inconvenient to observe the mixed solution of serum and tiger red plate aggregation antigen when there is insufficient light, and it is inconvenient to disinfect after detection, which poses a risk of infection.

Method used

A brucella antibody detection box was designed, including the box body, upper cover, glass plate, lighting lamp and disinfectant spraying assembly. The close-up observation is achieved by adjusting the angle of the lighting lamp and moving the bearing plate. The bearing plate is positioned using a magnet system, and after observation, the disinfectant spraying assembly is used to disinfect the mixture.

Benefits of technology

It is possible to easily observe the mixed solution of serum and tiger red plate aggregation antigen in close proximity under sufficient light conditions, reducing the risk of infection, and effectively disinfecting the mixed solution through disinfectant, improving the safety and convenience of detection.

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Abstract

The utility model relates to the technical field of brucella detection, in particular to a brucella antibody detection box. Comprising a box body, an upper cover is slidably arranged in the upper end of the box body, a plurality of vertical spring telescopic rods are fixed to the lower end of the upper cover, the lower ends of the spring telescopic rods abut against a bottom plate of the box body, a window is formed in the upper cover, a glass plate is fixed in the window, and balls are rotatably arranged on the portions, on the two sides of the window, of the upper cover and penetrate through the upper cover; an upper magnet is placed at the upper end of the floor of the box body, the upper magnet and the lower magnet are attracted through magnetic force, and the upper end of the upper magnet is detachably connected with a bearing disc. After the upper cover moves downwards, the glass plate is close to the bearing plate, so that a mixed solution of the serum and the tiger red plate agglutination antigen can be conveniently observed in a short distance. And the irradiation angle of the illuminating lamp is adjustable, so that the irradiation angle of the illuminating lamp is convenient to adjust, and a mixed solution of serum and a tiger red flat plate agglutination antigen is convenient to observe.
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Description

Technical Field

[0001] The utility model relates to the technical field of Brucella detection, in particular to a Brucella antibody detection kit. Background Art

[0002] Brucella is a class of Gram-negative short bacilli. Animals such as cattle, sheep, and pigs are most susceptible to infection, causing infectious abortion in female livestock. Humans can be infected by contacting infected animals or consuming diseased livestock and their dairy products. The genus Brucella is divided into 6 species and 20 biotypes, including Brucella melitensis, Brucella abortus, Brucella suis, Brucella neotomae, Brucella ovis, and Brucella canis. When rapidly detecting Brucella, 30 μL of the serum to be tested is dropped onto a slide, and then 30 μL of the Rose Bengal plate agglutination antigen is dropped into the serum. After 5 minutes, observe whether there are visible particles in the mixture under sufficient light. If particles are produced, it is positive, indicating that the serum contains Brucella; otherwise, it does not contain Brucella. Sufficient light is required when observing whether there are visible particles in the mixture of the serum and the Rose Bengal plate agglutination antigen. During the self-testing process by some farmers in the breeding site, since the light intensity of natural light changes with time, and at the same time, the conditions of the breeding site are limited, it is inconvenient to observe the mixture of the serum and the Rose Bengal plate agglutination antigen when the light is insufficient. At the same time, without a suitable detection device, it is easy to be infected with Brucella after the tester comes into contact with the serum to be tested.

[0003] A patent document with the publication number CN211014313U discloses a Brucella antibody detection kit. When in use, first collect a sample into a sample bottle, select a dilution bottle with a suitable dilution ratio according to the type of the sample, open the bottle cap, use a dropper to take a drop of the sample into the diluent in the dilution bottle, tighten the cap and shake well, align the bottle cap with the sample addition hole, and gently press the bottle body to release the diluted sample into the detection component. After a few minutes, the detection result can be observed through the observation window. The used dilution bottle and the detection component are directly discarded. The technical solution disclosed in this patent document mainly relies on a Brucella antibody detection card for detection, which is not suitable for detecting Brucella using the Rose Bengal plate agglutination antigen. At the same time, the cost of detecting Brucella using the Brucella antibody detection card is relatively high.

[0004] The patent document with the publication number CN211554022U discloses a rapid detection device for Brucella. During the detection, 30 μL of the serum to be tested is dropped onto the specimen slide, and then 30 μL of the Rose Bengal plate agglutination antigen is dropped into the serum. Pull the handle to open the sealing plate, move the specimen slide with the mixed solution of serum and Rose Bengal plate agglutination antigen to the stage in the inner cavity of the detection box, and then restore the sealing plate. After 5 minutes, turn on the switch so that its storage battery powers the LED lamp, thereby lighting up the inner cavity of the detection box. Lean the eyes against the observation tube, put both hands into the rubber gloves, and move the specimen slide through the rubber gloves by hand to adjust to the best viewing angle, so as to observe whether there are visible particles to the naked eye in the mixed solution of serum and Rose Bengal plate agglutination antigen under sufficient light. If particles are produced, it is positive, indicating that the serum contains Brucella; otherwise, it does not contain Brucella. During the detection of Brucella, the light in the detection box is sufficient, and the specimen slide can be moved to facilitate the observation of the mixed solution of serum and Rose Bengal plate agglutination antigen. However, it is not convenient to observe the mixed solution of serum and Rose Bengal plate agglutination antigen at a close distance. Moreover, it is not convenient to disinfect the mixed solution of serum and Rose Bengal plate agglutination antigen on the specimen slide after detection. Utility Model Content

[0005] The technical problem to be solved by the present utility model is a Brucella antibody detection box that can facilitate the mixed solution of serum and Rose Bengal plate agglutination antigen on the specimen slide to be close to the eyes of the detector, facilitating the detector to observe the mixed solution of serum and Rose Bengal plate agglutination antigen at a close distance. After the detection of the Brucella antibody detection box is completed, it is convenient to disinfect the mixed solution of serum and Rose Bengal plate agglutination antigen on the specimen slide.

[0006] To achieve the above object, the technical solution provided by the present utility model is:

[0007] A Brucella antibody detection box includes a box body. An upper cover is slidably arranged inside the upper end of the box body. A plurality of vertical spring telescopic rods are fixed to the lower end of the upper cover, and the lower ends of the spring telescopic rods tightly abut against the bottom plate of the box body. A viewing window is opened on the upper cover, and a glass plate is fixed inside the viewing window. Spheres are rotatably arranged on both sides of the viewing window on the upper cover. The spheres penetrate through the upper cover. A support rod is fixed to the upper end of the sphere, a power source is fixed to the lower end of the sphere, and a lighting lamp is fixed to the lower end of the power source. The power source is electrically connected to the lighting lamp. A groove is opened at the lower end of the box body, and an elastic rope is fixed inside the groove. The elastic rope penetrates through the hole on the lower magnet. An upper magnet is placed on the upper end of the floor of the box body, and the upper magnet is adsorbed to the lower magnet. During the process of moving the lower magnet, the upper magnet can move in the box body along with the lower magnet. The upper end of the upper magnet is detachably connected with a carrier plate. A disinfectant spraying assembly is arranged on the upper cover on one side of the viewing window.

[0008] Specifically, a switch is fixed to the upper end of the support rod, and the switch is electrically connected to the power source on one side of it.

[0009] Specifically, a jack is provided at the upper end of the upper magnet, and a plug rod is fixed to the lower end of the bearing plate. The plug rod is inserted into the jack.

[0010] Specifically, a plurality of iron blocks are inlaid and fixed at the lower end of the bearing plate, and the upper magnet magnetically adsorbs the plurality of iron blocks.

[0011] Specifically, the disinfectant spraying assembly includes a spray pipe, the spray pipe has a vertical portion and an inclined portion, the vertical portion of the spray pipe is rotatably connected to the upper cover, the vertical portion of the spray pipe penetrates through the upper cover, a rotating ring is fixed on the vertical portion of the spray pipe above the upper cover, the spray pipe can be rotated through the rotating ring, the inclined portion of the spray pipe is located in the space between the upper cover and the box body, the outlet end of the inclined portion of the spray pipe is inclined downward, a spray head is fixedly communicated with the outlet end of the inclined portion of the spray pipe, a pressure valve assembly is installed in the spray pipe, the upper end of the spray pipe is communicated with the lower end of an elastic balloon, the upper end of the balloon is fixedly communicated with an inlet pipe, and the upper end of the inlet pipe is detachably and fixedly sealed and connected with a sealing cover.

[0012] Specifically, the pressure valve assembly is installed in the vertical portion of the spray pipe. The pressure valve assembly includes an inner plate fixed in the vertical portion of the spray pipe. A plurality of through holes are circumferentially and evenly arranged on the inner plate. A rubber plate is arranged in the spray pipe below the inner plate. The middle of the rubber plate is fixedly connected with the inner plate, and the rubber plate blocks the plurality of through holes.

[0013] Specifically, the rubber plate is made of elastic rubber material.

[0014] Specifically, the outer edge of the bearing plate bulges upward.

[0015] Compared with the prior art, the beneficial effects of the present utility model are as follows:

[0016] 1. This detection box stores the mixed solution of serum and rose bengal plate agglutination antigen on the bearing plate. The outer edge of the bearing plate bulges upward, and when the bearing plate is moved, it can prevent the mixed solution of serum and rose bengal plate agglutination antigen from flowing out of the bearing plate. By moving the bearing plate, the bearing plate corresponds to the glass plate, and the best viewing angle can be adjusted, which is convenient for observing the mixed solution of serum and rose bengal plate agglutination antigen.

[0017] 2. The upper cover can move downward. After the upper cover moves downward, the glass plate is close to the bearing plate, which is convenient for observing the mixed solution of serum and rose bengal plate agglutination antigen at a close distance.

[0018] 3. The irradiation angle of the lighting lamp is adjustable, which is convenient for adjusting the irradiation angle of the lighting lamp and convenient for observing the mixed solution of serum and rose bengal plate agglutination antigen.

[0019] 4. After the detection is completed, the disinfectant spraying assembly can spray disinfectant into the bearing plate, which is convenient for disinfecting the mixed solution of serum and rose bengal plate agglutination antigen.

[0020] 5. During the detection process, the upper cover and the box body isolate the mixed solution of serum and brucella antigen on the carrier plate from the tester, which can prevent the tester from accidentally touching the mixed solution of serum and brucella antigen and reduce the probability of the tester being infected with brucella. Description of the Drawings

[0021] Figure 1 This is a schematic diagram of this test kit.

[0022] Figure 2 This is a top view of this test kit.

[0023] Figure 3 is Figure 2 the sectional view taken along the line A-A in

[0024] Figure 4 the sectional view of the carrier plate, the upper magnet and the lower magnet.

[0025] Figure 5 is Figure 4 the enlarged view of area B in

[0026] The names of the components in the drawings are: 1. Box body, 2. Upper cover, 3. Glass plate, 4. Sphere, 5. Support rod, 6. Power supply, 7. Lighting lamp, 8. Spring telescopic rod, 9. Lower magnet, 10. Elastic rope, 11. Groove, 12. Spray pipe, 13. Sprayer, 14. Rotating ring, 15. Balloon, 16. Inlet pipe, 17. Carrier plate, 18. Insert rod, 19. Upper magnet, 20. Jack, 21. Iron block, 22. Inner plate, 23. Through hole, 24. Rubber plate. Detailed Embodiments

[0027] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments.

[0028] Embodiment 1: Referring to Figures 1 - 4 As shown, a brucella antibody test kit includes a box body 1, an upper cover 2 is slidably arranged inside the upper end of the box body 1, a plurality of vertical spring telescopic rods 8 are fixed to the lower end of the upper cover 2, the lower ends of the spring telescopic rods 8 tightly abut against the bottom plate of the box body 1, a viewing window is opened on the upper cover 2, and a glass plate 3 is fixed in the viewing window.

[0029] Press down the upper cover 2, and the upper cover 2 can move towards the bottom plate of the box body 1. At the same time, the spring telescopic rod 8 contracts.

[0030] Spheres 4 are rotatably arranged on the upper covers 2 on both sides of the window. The spheres 4 penetrate through the upper covers 2. A support rod 5 is fixed to the upper end of the sphere 4, a power source 6 is fixed to the lower end of the sphere 4, and a lighting lamp 7 is fixed to the lower end of the power source 6. The power source 6 is electrically connected to the lighting lamp 7. A switch is fixed to the upper end of the support rod 5, and the switch is electrically connected to the power source 6 on one side thereof.

[0031] When the switch is turned on, the power source 6 supplies power to the lighting lamp 7, and the lighting lamp 7 provides illumination inside the box body 1. The sphere 4 can be rotated through the support rod 5. When the sphere 4 rotates, the power source 6 and the lighting lamp 7 on the sphere 4 move. Therefore, the irradiation angle of the lighting lamp 7 can be changed during the rotation of the sphere 4. Thus, appropriate-angle illumination can be provided for the mixture of the serum and the rose bengal plate agglutination antigen, facilitating the detection personnel to observe whether there are particles in the mixture of the serum and the rose bengal plate agglutination antigen.

[0032] A groove 11 is opened at the lower end of the box body 1. An elastic cord 10 is fixed in the groove 11. The elastic cord 10 penetrates through the hole in the lower magnet 9. An upper magnet 19 is placed on the upper end of the floor of the box body 1. The upper magnet 19 is adsorbed to the lower magnet 9. The upper magnet 19 can move in the box body 1 along with the lower magnet 9 during the movement of the lower magnet 9. The upper magnet 19 is detachably connected to a bearing plate 17 at its upper end. Specifically, the outer edge of the bearing plate 17 protrudes upward. A jack 20 is opened at the upper end of the upper magnet 19. A plug rod 18 is fixed to the lower end of the bearing plate 17, and the plug rod 18 is inserted into the jack 20. A plurality of iron blocks 21 are inlaid and fixed at the lower end of the bearing plate 17, and the upper magnet 19 magnetically adsorbs the plurality of iron blocks 21.

[0033] By moving the lower magnet 9, the upper magnet 19 and the bearing plate 17 can move accordingly, which can conveniently adjust the position of the bearing plate 17 in the box body 1 and facilitate observing the mixture of the serum and the rose bengal plate agglutination antigen in the bearing plate 17 through the glass plate 3. The elastic cord 10 penetrates through the hole in the lower magnet 9, which can prevent the lower magnet 9 from being lost.

[0034] During detection, the upper cover 2 is taken out of the box body 1, then 30 μL of the serum to be tested is dropped into the bearing plate 17, and then 30 μL of the rose bengal plate agglutination antigen is dropped into the serum. Then the upper cover 2 is placed inside the upper end of the box body 1. After waiting for 5 minutes, the mixture of the serum and the rose bengal plate agglutination antigen is observed.

[0035] When observing the mixture of the serum and the rose bengal plate agglutination antigen, the switch is turned on, and the lighting lamp 7 provides illumination inside the box body 1. The sphere 4 can be rotated through the support rod 5. When the sphere 4 rotates, the power source 6 and the lighting lamp 7 on the sphere 4 move. Therefore, the irradiation angle of the lighting lamp 7 can be changed during the rotation of the sphere 4. Thus, appropriate-angle illumination can be provided for the mixture of the serum and the rose bengal plate agglutination antigen, facilitating the detection personnel to observe the mixture of the serum and the rose bengal plate agglutination antigen.

[0036] Moving the lower magnet 9 can cause the upper magnet 19 and the carrier plate 17 to move accordingly, which can conveniently adjust the position of the carrier plate 17 in the box body 1 and facilitate the observation of the mixture of serum and tiger red plate agglutination antigen in the carrier plate 17 by the light-transmitting glass plate 3.

[0037] Meanwhile, the upper cover 2 can be pressed down. The upper cover 2 can move downward. When the upper cover 2 moves downward in the box body 1, the spring telescopic rod 8 contracts. After the upper cover 2 moves downward, the glass plate 3 approaches the carrier plate 17, which is convenient for the close observation of the mixture of serum and tiger red plate agglutination antigen.

[0038] Under sufficient light, check whether there are visible particles to the naked eye in the mixture of serum and tiger red plate agglutination antigen. If particles are produced, it is positive, indicating that the serum contains Brucella; otherwise, it does not contain Brucella.

[0039] Example 2: On the basis of Example 1, referring to Figure 3 , Figure 4 and Figure 5 As shown, a disinfectant spraying assembly is provided on the upper cover 2 on one side of the window. The disinfectant spraying assembly includes a spray pipe 12. The spray pipe 12 has a vertical portion and an inclined portion. The vertical portion of the spray pipe 12 is rotatably connected to the upper cover 2. The vertical portion of the spray pipe 12 penetrates through the upper cover 2. A rotating ring 14 is fixed on the vertical portion of the spray pipe 12 above the upper cover 2. The spray pipe 12 can be rotated through the rotating ring 14. The inclined portion of the spray pipe 12 is located in the space between the upper cover 2 and the box body 1. The outlet end of the inclined portion of the spray pipe 12 is inclined downward. The outlet end of the inclined portion of the spray pipe 12 is fixedly communicated with a spray head 13. A pressure valve assembly is installed in the spray pipe 12. The upper end of the spray pipe 12 is communicated with the lower end of an elastic balloon 15. The upper end of the balloon 15 is fixedly communicated with an inlet pipe 16. The upper end of the inlet pipe 16 is detachably and fixedly sealed and connected with a sealing cover.

[0040] Opening the sealing cover allows disinfectant to be added into the balloon 15. The disinfectant is stored in the balloon 15. When the balloon 15 is not squeezed, the disinfectant will not be sprayed out from the spray head 13.

[0041] The pressure valve assembly is installed in the vertical portion of the spray pipe 12. The pressure valve assembly includes an inner plate 22 fixed in the vertical portion of the spray pipe 12. A plurality of through holes 23 are circumferentially and uniformly formed in the inner plate 22. A rubber plate 24 is arranged in the spray pipe 12 below the inner plate 22. The middle of the rubber plate 24 is fixedly connected with the inner plate 22. The rubber plate 24 blocks the plurality of through holes 23. The rubber plate 24 is made of elastic rubber material.

[0042] When observing the mixture of serum and tiger red plate agglutination antigen, the spray pipe 12 needs to be rotated so that the inclined portion of the spray pipe 12 is located on one side of the carrier plate 17, preventing the inclined portion of the spray pipe 12 from blocking the line of sight of the tester when observing the mixture of serum and tiger red plate agglutination antigen.

[0043] After observing that the mixture of the serum and the rose bengal plate agglutination antigen is completed, rotate the spray pipe 12 through the rotating ring 14 so that the nozzle 13 is located above the carrier plate 17. Then squeeze the balloon 15. After the balloon 15 is squeezed, the pressure inside it increases. After the disinfectant liquid in the balloon 15 acts on the rubber plate 24, the rubber plate 24 deforms. Then the disinfectant liquid passes through the through hole 23 and is sprayed out from the nozzle 13 onto the carrier plate 17. The disinfectant liquid entering the carrier plate 17 disinfects the mixture of the serum and the rose bengal plate agglutination antigen.

[0044] The above are only the preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent replacements, and improvements made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.

Claims

1. A Brucella antibody detection kit, comprising a box body (1), characterized in that, A lid (2) is slidably arranged inside the upper end of the box body (1). A plurality of vertical spring telescopic rods (8) are fixed to the lower end of the lid (2). The lower ends of the spring telescopic rods (8) tightly abut against the bottom plate of the box body (1). A viewing window is provided on the lid (2), and a glass plate (3) is fixed inside the viewing window. Spheres (4) are rotatably arranged on both sides of the viewing window on the lid (2). The spheres (4) penetrate through the lid (2). A support rod (5) is fixed to the upper end of the sphere (4), a power supply (6) is fixed to the lower end of the sphere (4), and a lighting lamp (7) is fixed to the lower end of the power supply (6). The power supply (6) is electrically connected to the lighting lamp (7). A groove (11) is provided at the lower end of the box body (1), and an elastic cord (10) is fixed inside the groove (11). The elastic cord (10) penetrates through the hole in the lower magnet (9). An upper magnet (19) is placed on the upper end of the floor of the box body (1). The upper magnet (19) is adsorbed to the lower magnet (9). During the process of moving the lower magnet (9), the upper magnet (19) can move inside the box body (1) along with the lower magnet (9). The upper end of the upper magnet (19) is detachably connected to a bearing plate (17). A disinfectant spraying assembly is provided on the lid (2) on one side of the viewing window.

2. The Brucella antibody detection kit according to claim 1, wherein A switch is fixed to the upper end of the support rod (5), and the switch is electrically connected to the power supply (6) on one side thereof.

3. The Brucella antibody detection kit according to claim 1, wherein, A jack (20) is provided at the upper end of the upper magnet (19), and a plug rod (18) is fixed to the lower end of the bearing plate (17). The plug rod (18) is inserted into the jack (20).

4. The Brucella antibody detection kit according to claim 3, characterized in that, A plurality of iron blocks (21) are inlaid and fixed to the lower end of the bearing plate (17), and the upper magnet (19) magnetically adsorbs the plurality of iron blocks (21).

5. The Brucella antibody detection kit according to claim 1, wherein The disinfectant spraying assembly includes a spray pipe (12). The spray pipe (12) has a vertical part and an inclined part. The vertical part of the spray pipe (12) is rotatably connected to the lid (2). The vertical part of the spray pipe (12) penetrates through the lid (2). A rotating ring (14) is fixed to the vertical part of the spray pipe (12) above the lid (2). The spray pipe (12) can be rotated through the rotating ring (14). The inclined part of the spray pipe (12) is located in the space between the lid (2) and the box body (1). The outlet end of the inclined part of the spray pipe (12) is inclined downward. A spray head (13) is fixedly communicated with the outlet end of the inclined part of the spray pipe (12). A pressure valve assembly is installed inside the spray pipe (12). The upper end of the spray pipe (12) is communicated with the lower end of an elastic balloon (15). The upper end of the balloon (15) is fixedly communicated with an inlet pipe (16). The upper end of the inlet pipe (16) is detachably and fixedly sealed and connected with a sealing cover.

6. The Brucella antibody detection kit according to claim 5, wherein, The pressure valve assembly is installed inside the vertical part of the spray pipe (12). The pressure valve assembly includes an inner plate (22) fixed inside the vertical part of the spray pipe (12). A plurality of through holes (23) are circumferentially and evenly arranged on the inner plate (22). A rubber plate (24) is arranged inside the spray pipe (12) below the inner plate (22). The middle part of the rubber plate (24) is fixedly connected to the inner plate (22). The rubber plate (24) blocks the plurality of through holes (23).

7. The Brucella antibody detection kit according to claim 6, wherein The rubber plate (24) is made of elastic rubber material.

8. The Brucella antibody detection kit according to claim 1, characterized in that, The outer edge of the bearing plate (17) bulges upward.

Citation Information

Patent Citations

  • Brucella antibody detection kit

    CN211014313U

  • Brucella rapid detection device

    CN211554022U