Antibody detection card

Abstract

The utility model provides an antibody detection card, which belongs to the technical field of antibody detection and comprises a shell. The cover plate is connected to the upper end of the shell; the bayonet is formed in the side end of the shell, the side end of the cover plate is fixedly connected with a clamping block, and the bayonet is matched with the clamping block; the display area is arranged between the shell and the cover plate; the sample adding hole is formed in the side end of the display area; according to the scheme, the antibody detection card is simple in design, a user only needs to add a sample to be detected through the sample adding hole, close the cover plate and wait for a period of time, and then the detection result can be observed through the display area. The simple and convenient operation process enables a user to rapidly and conveniently detect specific antigens, and complex instruments and professional knowledge are not needed.

Description

Technical Field

[0001] The utility model belongs to the technical field of antibody detection, and particularly relates to an antibody detection card. Background Art

[0002] The immunochromatographic test card is an in vitro diagnostic tool widely used for rapid detection of specific biomolecules (such as antigens or antibodies). Based on the principle of immunochromatography, the immunochromatographic test card uses antibodies or other biorecognition molecules immobilized on a solid-phase carrier (such as nitrocellulose membrane) to specifically bind to the target molecules in the sample, and the detection result is quickly and visually displayed through the color reaction of a labeling agent (such as colloidal gold).

[0003] Traditional immunochromatographic test cards may require complex operation steps, including sample preparation, reagent mixing, use of specific equipment, etc., which may make it difficult for non-professionals to use. Content of the Utility Model

[0004] The purpose of the utility model is to provide an antibody detection card, aiming to solve the problem that traditional immunochromatographic test cards in the prior art may require complex operation steps, including sample preparation, reagent mixing, use of specific equipment, etc., which may make it difficult for non-professionals to use.

[0005] To achieve the above purpose, the utility model provides the following technical solutions:

[0006] An antibody detection card, comprising:

[0007] A housing;

[0008] A cover plate, which is connected to the upper end of the housing;

[0009] A bayonet, which is opened on the side end of the housing. A clamping block is fixedly connected to the side end of the cover plate, and the bayonet and the clamping block are matched;

[0010] A display area, which is arranged between the housing and the cover plate;

[0011] A sample adding hole, which is arranged at the side end of the display area;

[0012] An exhaust hole, which is arranged at the upper end of the cover plate.

[0013] As a preferred solution of the utility model, a scale line is arranged at the upper end of the cover plate, and a clamping groove is opened at the upper end of the housing.

[0014] As a preferred solution of the utility model, a positioning member is arranged between the housing and the cover plate.

[0015] As a preferred embodiment of the present utility model, a reference area is provided at the upper end of the cover plate.

[0016] As a preferred embodiment of the present utility model, the interior of the housing includes a nitrocellulose membrane, a gold-labeled pad, and absorbent paper.

[0017] As a preferred embodiment of the present utility model, the display area includes a polycarbonate layer, a biocompatible layer, and an anti-static coating.

[0018] Compared with the prior art, the beneficial effects of the present utility model are as follows:

[0019] 1. In this solution, the antibody test card in this solution is simply designed. The user only needs to add the sample to be tested through the sample addition hole, close the cover plate, and then wait for a period of time to observe the test result through the display area. This simple operation process enables the user to quickly and conveniently detect specific antigens without complex instruments and professional knowledge.

[0020] 2. In this solution, the antibody test card in this solution uses components such as a nitrocellulose membrane, a gold-labeled pad, and absorbent paper, combined with the polycarbonate layer, biocompatible layer, and anti-static coating in the display area, ensuring the accuracy and reliability of the test results. The combination of these components enables the test card to quickly detect specific antigens through the principle of immunochromatography. The user can judge whether the target antigen is contained in the sample by observing whether specific lines or color changes appear in the display area. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] The drawings are used to provide a further understanding of the present utility model and constitute a part of the specification. They are used together with the embodiments of the present utility model to explain the present utility model and do not constitute a limitation to the present utility model. In the drawings:

[0022] Figure 1 is a perspective view of the present utility model;

[0023] Figure 2 is an exploded view of the present utility model;

[0024] Figure 3 is the present utility model Figure 2 an enlarged internal view of part A in;

[0025] Figure 4 is the present utility model Figure 2 an enlarged internal view of part B in.

[0026] In the figure: 1. Housing; 101. Nitrocellulose membrane; 102. Gold-labeled pad; 103. Absorbent paper; 1011. Polycarbonate layer; 1022. Biocompatible layer; 1033. Antistatic coating; 2. Cover plate; 3. Bayonet; 4. Block; 5. Card slot; 6. Positioning member; 7. Scale line; 8. Display area; 9. Sampling hole; 10. Exhaust hole; 11. Reference area. Detailed implementation mode

[0027] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0028] Embodiment 1

[0029] Please refer to Figures 1-4 , the present invention provides the following technical solutions:

[0030] An antibody detection card, comprising:

[0031] Housing 1;

[0032] Cover plate 2, the cover plate 2 is connected to the upper end of the housing 1;

[0033] Bayonet 3, the bayonet 3 is opened on the side end of the housing 1, and a block 4 is fixedly connected to the side end of the cover plate 2, and the bayonet 3 and the block 4 are matched;

[0034] Display area 8, the display area 8 is arranged between the housing 1 and the cover plate 2;

[0035] Sampling hole 9, the sampling hole 9 is arranged at the side end of the display area 8;

[0036] Exhaust hole 10, the exhaust hole 10 is arranged at the upper end of the cover plate 2.

[0037] In a specific embodiment of the present utility model, the housing 1 is the main part of the antibody detection card, which is used to accommodate and fix other components. The cover plate 2 is connected to the upper end of the housing 1 and can cover the housing to protect the internal structure. The bayonet 3 is opened at the side end of the housing 1 and is used to cooperate with the block 4 to ensure that the cover plate 2 can be firmly connected to the housing. The display area 8 is located between the housing 1 and the cover plate 2 and is used to display the detection result or provide operation instructions. The sample addition hole 9 is provided at the side end of the display area 8 and is the entrance for the user to add the sample to be detected. The exhaust hole 10 is provided at the upper end of the cover plate 2 and is used to discharge the internal air during the sample addition process to ensure that the sample can smoothly enter the detection area. In specific implementation, the user adds the sample to be detected into the antibody detection card through the sample addition hole 9, and then the cover plate 2 is fixed on the housing 1 by the block 4 to ensure that the sample does not leak. The exhaust hole 10 provided on the cover plate 2 can help to remove the bubbles generated during the sample addition to ensure the accuracy of the detection. The display area 8 can be various forms of indicators, such as color changes caused by chemical reactions, barcodes, liquid crystal displays, etc., which are used to intuitively display the detection result. The antibody detection card of the present utility model has a simple design and convenient operation, can quickly and accurately provide the detection result, and is applicable to multiple fields such as medical treatment, scientific research, and food safety.

[0038] For details, please refer to Figures 1-4 , a scale line 7 is provided at the upper end of the cover plate 2, and a card slot 5 is opened at the upper end of the housing 1.

[0039] In this embodiment: A scale line 7 is provided at the upper end of the cover plate 2, which can provide a reference for the user to add the sample and ensure that the amount of the sample added by the user is accurate. The scale line 7 can be directly printed on the cover plate 2 or formed by other means, such as stickers, scratches, etc. At the same time, a card slot 5 is opened at the upper end of the housing 1, and this card slot 5 can be used to fix the cover plate 2 or cooperate with other components to enhance the stability of the entire antibody detection card. The shape and size of the card slot 5 should match the cover plate 2 so that the cover plate 2 can be smoothly inserted into the card slot 5. Considering these designs, the antibody detection card in this embodiment is not only easy to operate, but also can provide the accuracy of sample addition through the scale line 7 and the structural stability through the card slot 5, thereby improving the reliability of the detection and the user experience.

[0040] For details, please refer to Figures 1-4 , a positioning member 6 is provided between the housing 1 and the cover plate 2.

[0041] In this embodiment: A positioning member 6 is provided between the housing 1 and the cover plate 2. The function of this positioning member 6 is to ensure that the cover plate 2 and the housing 1 can be accurately aligned when closed, so as to facilitate the correct positions of the sample addition hole 9 and the exhaust hole 10, as well as the visibility of the display area 8. The positioning member 6 can be a structure such as a protrusion, a groove or a buckle, etc. When the cover plate 2 and the housing 1 are closed, the positioning members 6 can cooperate with each other, so that the cover plate 2 is locked in the correct position, avoiding problems such as inaccurate sample addition caused by position deviation or the inability to observe the display area 8. By setting the positioning member 6, the antibody detection card in this embodiment not only has a stable structure, but also can ensure the operation accuracy of the user during use and the reliability of the detection result. This design improves the overall performance of the detection card and makes it more suitable for quickly and simply performing antibody detection.

[0042] For details, please refer to Figures 1-4 , and a reference area 11 is provided at the upper end of the cover plate 2.

[0043] In this embodiment: A reference area 11 is provided at the upper end of the cover plate 2. The setting of this reference area 11 is to provide a visual or physical reference, so that users can have a clear guidance when operating the antibody detection card. The reference area 11 can be used for various purposes, such as:

[0044] Mark the position of sample addition: The reference area 11 can indicate to the user where to add the sample, ensuring that the sample is accurately added into the sample addition hole 9.

[0045] Show the operation steps: The reference area 11 can provide simplified diagrams of the operation steps to help users use the detection card according to the correct process.

[0046] For details, please refer to Figures 1-4 , and the housing 1 includes a nitrocellulose membrane 101, a gold-labeled pad 102 and a blotting paper 103.

[0047] In this embodiment: The housing 1 includes a nitrocellulose membrane 101, a gold-labeled pad 102 and a blotting paper 103. These are common components in the immunochromatographic detection card and are used for rapid and qualitative immunoassay.

[0048] Nitrocellulose membrane 101: This is a commonly used solid-phase carrier for immobilizing antibodies or other biorecognition molecules. After the sample is added to the detection card through the sample addition hole 9, it will move on the nitrocellulose membrane. If specific antigens exist in the sample, they will bind to the antibodies on the membrane to form immune complexes.

[0049] Gold Label Marking Pad 102: This is a pad containing antibodies or antigens labeled with colloidal gold. The gold-labeled antibodies or antigens will move along with the sample on the nitrocellulose membrane. If the target antigen exists in the sample, the gold-labeled antibodies will bind to it, forming visible immunocomplex lines.

[0050] Absorbent Paper 103: This is a kind of absorbent material used to absorb and guide the movement of the sample on the nitrocellulose membrane. Absorbent Paper 103 ensures that the sample can move evenly across the membrane and helps react the antigen in the sample with the labeled antibodies or antigens in the gold label marking pad. The combination of these components enables the antibody test card to quickly detect specific antigens through the principle of immunochromatography. By observing whether specific lines or color changes appear in the display area 8, the user can determine whether the target antigen is contained in the sample. This test card is suitable for point-of-care testing (POCT) and has a wide range of applications in the fields of medical treatment, disease control, food safety, etc.

[0051] For details, please refer to Figures 1-4 , and the display area 8 includes a polycarbonate layer 1011, a biocompatible layer 1022, and an antistatic coating 1033.

[0052] In this embodiment: The display area 8 includes a polycarbonate layer 1011, a biocompatible layer 1022, and an antistatic coating 103, and the settings of these layers are designed to improve the functionality and reliability of the display area 8, ensuring the accuracy of the test results and the safety of the user.

[0053] Polycarbonate Layer 1011: This is a transparent and strong material used to form the base layer of the display area 8. The polycarbonate layer 1011 provides structural support and allows the user to clearly observe any changes in the display area 8, such as color changes, line appearance, etc.

[0054] Biocompatible Layer 1022: This layer of material is used to ensure the compatibility of the antibody test card with biological samples, preventing adverse reactions between the biological molecules in the samples and the materials in the display area 8, thus ensuring the accuracy of the test results. The biocompatible layer 1022 can also protect the polycarbonate layer 1011 from the corrosion of substances that may be contained in biological samples.

[0055] Antistatic Coating 1033: Since some biomolecules may be sensitive to static electricity, the application of the antistatic coating 1033 can reduce the impact of static electricity on the sample and the test card, preventing sample contamination or damage caused by static electricity. In addition, the antistatic coating 1033 can also improve the stability of the test card during operation, avoiding misoperations caused by static electricity. In summary, these layers in the display area 8 enhance the overall performance of the antibody test card, enabling it to not only provide clear and reliable test results, but also protect the sample and the test card itself from unnecessary interference and damage. This design improves the applicability and user experience of the test card, especially in fields such as medical diagnosis and environmental monitoring that require precision and reliability.

[0056] Working Principle and Usage Process of the Present Utility Model: First, the user needs to prepare the sample to be tested, which usually involves blood, urine, saliva, or other biological fluids. The preparation of the sample may include dilution, stirring, or other specific pretreatment steps to ensure that the sample is suitable for testing. The user opens the cover plate 2 of the antibody test card from the housing 1, exposing the sample addition hole 9 and the display area 8. The upper end of the cover plate 2 may be provided with scale lines 7 and a reference area 11 to provide a reference for sample addition and operation guidelines. The user adds the prepared sample into the antibody test card through the sample addition hole 9. The amount of sample added can be referenced by the scale lines 7 on the cover plate 2 to ensure that the amount of sample added is accurate. After adding the sample, the user closes the cover plate 2, making it snap into the card slot 5 at the upper end of the housing 1. At this time, the latch block 4 fixedly connected to the side end of the cover plate 2 matches the bayonet 3 at the side end of the housing 1 to ensure that the cover plate 2 is firmly connected to the housing. At the same time, the user needs to ensure that the exhaust hole 10 is unobstructed to discharge the internal air. The user places the antibody test card for a period of time to allow the sample to flow inside the housing 1 and react with the nitrocellulose membrane 101, gold-labeled pad 102, and absorbent paper 103 inside. After a period of time, the user observes the result through the display area 8. The display area 8 includes a polycarbonate layer 1011, a biocompatible layer 1022, and an antistatic coating 1033, ensuring that the result is clearly visible. The user determines whether the target antigen is contained in the sample based on whether specific lines or color changes appear in the display area 8. The reference area 11 may provide guidelines for result interpretation.

[0057] Finally, it should be noted that the above are only the preferred embodiments of the present utility model and are not used to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, for those skilled in the art, they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements for some of the technical features. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present utility model shall be included within the protection scope of the present utility model.

Claims

1. An antibody detection card, characterized in that, Comprising: A housing (1); A cover plate (2), which is connected to the upper end of the housing (1); A bayonet (3) is provided on the side end of the housing (1), a latch block (4) is fixedly connected to the side end of the cover plate (2), and the bayonet (3) and the latch block (4) are matched; A display area (8) is arranged between the housing (1) and the cover plate (2); A sample addition hole (9) is arranged on the side end of the display area (8); An exhaust hole (10) is arranged on the upper end of the cover plate (2).

2. The antibody detection card according to claim 1, wherein: A scale line (7) is arranged on the upper end of the cover plate (2), and a card slot (5) is opened on the upper end of the housing (1).

3. The antibody detection card according to claim 2, wherein: A positioning member (6) is arranged between the housing (1) and the cover plate (2).

4. The antibody detection card according to claim 3, wherein: A reference area (11) is opened on the upper end of the cover plate (2).

5. An antibody detection card according to claim 4, characterized in that: The housing (1) includes a nitrocellulose membrane (101), a gold-labeled pad (102) and a blotting paper (103).

6. An antibody detection card according to claim 5, characterized in that: The display area (8) includes a polycarbonate layer (1011), a biocompatible layer (1022) and an antistatic coating (1033).

Images