Equipment for monitoring moisture of freeze-drying preparation on line

Abstract

The utility model relates to the technical field of freeze-drying preparation monitoring, in particular to a freeze-drying preparation on-line moisture monitoring device which comprises a measuring instrument, a weighing disc is installed on the surface of the measuring instrument, a machine frame is fixedly installed on the surface of the measuring instrument, and a machine cover is rotatably installed at a port of the machine frame. A heat insulation cover is fixedly installed on the inner side of the machine cover, a heating coil pipe is fixedly installed on the inner side of the machine cover, a carrier is placed on the surface of the weighing disc, a grinding structure is arranged on the surface of the carrier and comprises a rotating shaft rotationally connected to the inner side of the carrier, and a connecting strip is fixedly connected to the side wall of the rotating shaft. Through the arrangement of the grinding structure, the hardened freeze-drying preparation on the inner side of the carrier can be conveniently and flexibly ground, so that the hardened freeze-drying preparation can be conveniently evaporated after being ground, the time for monitoring the freeze-drying preparation in real time is shortened to a certain extent, and the monitoring efficiency of the moisture content in the freeze-drying preparation is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of freeze-dried preparation monitoring, in particular to a device for on-line monitoring of moisture in freeze-dried preparations. Background Art

[0002] The monitoring of freeze-dried preparations includes observing the appearance of freeze-dried products, including color, state (powder, block, etc.), solubility, etc., checking whether they meet the specification requirements, using appropriate analytical methods (such as HPLC, UV, etc.) to determine the content of active ingredients in freeze-dried products to ensure compliance with quality standards, using the Karl Fischer method or thermogravimetric method to determine the residual moisture content of freeze-dried products to ensure that it is lower than the specified moisture limit. In short, the monitoring of freeze-dried preparations involves multiple aspects and requires the use of scientific analytical methods to ensure that the product quality meets the standard requirements.

[0003] A Chinese patent with the publication number CN221464151U discloses a device for on-line monitoring of moisture in freeze-dried preparations. Inside the box body of the frame, there is a weighing pan, and a carrier mechanism is placed above the weighing body of the weighing pan. Inside the flip cover of the machine cover, there is a heating and drying mechanism. At the top of the shaft rod of the rotating shaft, there is a comb tooth plate, and on one side of the comb tooth plate directly opposite to the top of the shaft rod of the rotating shaft, there is a scraping plate. First, the carrier mechanism loaded with freeze-dried preparations is placed on the weighing pan to measure its initial weight. Then, the moisture in the freeze-dried preparations is dried by using the heating and drying mechanism. At the same time, through the stirring and scraping of the scraping plate and the combing and mixing of the comb tooth plate in the carrier mechanism, the freeze-dried preparations are fully turned over and dispersed. After drying, by weighing the freeze-dried preparations again through the weighing pan, the moisture in the freeze-dried preparations can be detected.

[0004] In the existing related technologies, there are often the following defects: during the process of on-line monitoring of the moisture in freeze-dried preparations, when there are some agglomerated freeze-dried preparations, it takes a long time to complete the moisture drying work of the freeze-dried preparations, wasting unnecessary time and reducing the efficiency of on-line monitoring of freeze-dried preparations.

[0005] Therefore, the utility model provides a device for on-line monitoring of moisture in freeze-dried preparations. Content of the Utility Model

[0006] The purpose of the utility model is to solve the defect in the existing technology that it takes a long time to dry the moisture of some agglomerated freeze-dried preparations, and a device for on-line monitoring of moisture in freeze-dried preparations is proposed.

[0007] To achieve the above object, the utility model adopts the following technical scheme: An equipment for on-line monitoring of moisture in freeze-dried preparations, including a measuring instrument, on the surface of which a weighing pan is installed, a frame is fixedly installed on the surface of the measuring instrument, a machine cover is rotatably installed at the port of the frame, a heat insulation cover is fixedly installed inside the machine cover, a heating coil is fixedly installed inside the machine cover, a carrier is placed on the surface of the weighing pan, and a crushing structure is provided on the surface of the carrier. The crushing structure includes a rotating shaft rotatably connected inside the carrier, a connecting strip is fixedly connected to the side wall of the rotating shaft, a plurality of first comb strips are uniformly and fixedly connected to the lower surface of the connecting strip, a limiting pin is fixedly connected to the lower surface of the carrier, a circular ring frame is slidably connected to the surface of the limiting pin, and a plurality of second comb strips are uniformly and fixedly connected to the surface of the circular ring frame, and the second comb strips slide through the carrier.

[0008] The effect achieved by the above components is that when the agglomerated freeze-dried preparation is pushed to the position of the second comb strip, during the alternating movement between the first comb strip and the second comb strip, the crushing work of the agglomerated freeze-dried preparation can be realized, thereby improving the evaporation efficiency of the freeze-dried preparation.

[0009] Preferably, two mounting rods are fixedly connected to the lower surface of the carrier, a mounting ring is fixedly connected to one end of the two mounting rods close to each other, and a motor is fixedly installed inside the mounting ring, and the output end of the motor is fixedly connected to the rotating shaft.

[0010] The effect achieved by the above components is that when the motor is started, the motor will drive the rotating shaft to rotate, thereby realizing the driving work of the connecting strip, and the first comb strip on the connecting strip can realize the real-time spreading and stirring work of the freeze-dried preparation on the carrier.

[0011] Preferably, a screw rod is rotatably connected inside the carrier, and the screw rod is threadedly connected to the inside of the circular ring frame.

[0012] The effect achieved by the above components is that when the screw rod is twisted, the driving work of the circular ring frame can be realized at this time.

[0013] Preferably, a rotating block is fixedly installed at the other end of the screw rod, and anti-slip lines are provided on the outside of the rotating block.

[0014] The effect achieved by the above components is that when the rotating block is rotated, the rotating block will drive the screw rod to twist.

[0015] Preferably, a cleaning structure is provided on the surface of the rotating shaft. The cleaning structure includes a limiting block fixedly connected to the side of the rotating shaft end, a rotating pin is rotatably connected inside the limiting block, a rotating frame is fixedly connected to the side wall of the rotating pin, two springs are fixedly connected to the bottom side of the rotating frame, the other ends of the two springs are fixedly connected to a scraping strip, and the scraping strip is slidably connected to the inside of the rotating frame.

[0016] The effects achieved by the above components are as follows: The scraping strip will be closely attached to the bottom wall of the vehicle under the action of the spring elastic force. At this time, when the motor is started to rotate, the scraping work of the freeze-dried preparation inside the vehicle can be realized, which facilitates the subsequent monitoring work of other freeze-dried preparations.

[0017] Preferably, four jack holes are evenly arranged on the surface of the rotating pin, a fixing block is fixedly connected to the surface of the limiting block, a bolt is threadedly connected inside the fixing block, and the size of the bolt is adapted to the size of the jack hole.

[0018] The effects achieved by the above components are as follows: Rotate the bolt inside the fixing block and insert the bolt into the inner side of the corresponding jack hole, and the fixing work of the rotated frame can be realized.

[0019] Preferably, a rotating plate is rotatably connected to the upper end of the frame.

[0020] The effects achieved by the above components are as follows: After the frame rotates to a position where it is in the same straight line as the connecting strip, rotate the bolt inside the fixing block and insert the bolt into the inner side of the corresponding jack hole, and the fixing work of the rotated frame can be realized.

[0021] In summary:

[0022] 1. In the present utility model, by setting the crushing structure, during the process of the staggered movement between the first comb strip and the second comb strip, the crushing work of the agglomerated freeze-dried preparation can be realized. By setting the crushing structure, the flexible crushing work of the agglomerated freeze-dried preparation inside the vehicle is facilitated, thereby facilitating the evaporation work after the agglomerated freeze-dried preparation is crushed, shortening the time for real-time monitoring of the freeze-dried preparation to a certain extent, and improving the monitoring efficiency of the water content in the freeze-dried preparation.

[0023] 2. In the present utility model, by setting the scraping structure, after the second comb strip is retracted, rotate the frame inside the limiting block. After the frame rotates to a position where it is in the same straight line as the connecting strip, rotate the bolt inside the fixing block and insert the bolt into the inner side of the corresponding jack hole, and the fixing work of the rotated frame can be realized. At this time, the scraping strip will be closely attached to the bottom wall of the vehicle under the action of the spring elastic force. At this time, when the motor is started to rotate, the scraping work of the freeze-dried preparation inside the vehicle can be realized, which facilitates the subsequent monitoring work of other freeze-dried preparations. By setting the scraping structure, the flexible scraping work of the adhered freeze-dried preparation inside the vehicle is facilitated, and the use performance of the water monitoring device for the freeze-dried preparation is further improved. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 is a three-dimensional structural schematic diagram of the present utility model;

[0025] Figure 2 is a structural schematic diagram of the vehicle in the present utility model;

[0026] Figure 3 Another perspective structural schematic diagram of the present utility model; Figure 2

[0027] Figure 4 Magnified view of part A of the present utility model; Figure 2

[0028] Figure 5 Magnified view of part B of the present utility model; Figure 2

[0029] Legend: 1. Measuring instrument; 2. Weighing pan; 3. Carrier; 4. Machine cover; 5. Heating coil; 6. Heat shield; 7. Crushing structure; 701. Connecting bar; 702. First comb bar; 703. Second comb bar; 704. Rotating shaft; 705. Ring frame; 706. Limit pin; 707. Motor; 708. Mounting ring; 709. Mounting rod; 710. Screw rod; 711. Rotating block; 8. Scraping structure; 81. Rotating frame; 82. Scraping bar; 83. Limit block; 84. Rotating pin; 85. Bolt; 86. Fixed block; 87. Rotating plate; 88. Spring; 89. Jack; 9. Machine frame. Detailed implementation manners

[0030] Referring to Figure 1 As shown, the present utility model provides a technical solution: An equipment for on-line monitoring of moisture in freeze-dried preparations, including a measuring instrument 1, a weighing pan 2 is installed on the surface of the measuring instrument 1, a machine frame 9 is fixedly installed on the surface of the measuring instrument 1, a machine cover 4 is rotatably installed at the port of the machine frame 9, a heat shield 6 is fixedly installed inside the machine cover 4, a heating coil 5 is fixedly installed inside the machine cover 4, a carrier 3 is placed on the surface of the weighing pan 2, a crushing structure 7 is provided on the surface of the carrier 3, and a scraping structure 8 is provided on the surface of the rotating shaft 704.

[0031] The following specifically describes the specific settings and functions of its crushing structure 7 and scraping structure 8.

[0032] Referring to Figures 1-3As shown in the figure, in this embodiment: The crushing structure 7 includes a rotating shaft 704 rotatably connected to the inside of the vehicle 3. A connecting bar 701 is fixedly connected to the side wall of the rotating shaft 704. A plurality of first comb bars 702 are uniformly and fixedly connected to the lower surface of the connecting bar 701. A limiting pin 706 is fixedly connected to the lower surface of the vehicle 3. A circular ring frame 705 is slidably connected to the surface of the limiting pin 706. A plurality of second comb bars 703 are uniformly and fixedly connected to the surface of the circular ring frame 705. The second comb bars 703 slidably penetrate through the vehicle 3. When the agglomerated freeze-dried preparation is pushed to the position of the second comb bars 703, during the interleaved movement between the first comb bars 702 and the second comb bars 703, the crushing work of the agglomerated freeze-dried preparation can be realized, thereby improving the evaporation efficiency of the freeze-dried preparation. Two mounting rods 709 are fixedly connected to the lower surface of the vehicle 3. A mounting ring 708 is fixedly connected to one end of the two mounting rods 709 close to each other. A motor 707 is fixedly installed inside the mounting ring 708. The output end of the motor 707 is fixedly connected to the rotating shaft 704. When the motor 707 is started, the motor 707 will drive the rotating shaft 704 to rotate, thereby realizing the driving rotation work of the connecting bar 701. The first comb bars 702 on the connecting bar 701 can realize the real-time leveling and stirring work of the freeze-dried preparation on the vehicle 3. A screw rod 710 is rotatably connected to the inside of the vehicle 3. The screw rod 710 is threadedly connected to the inside of the circular ring frame 705. Driving the screw rod 710 to twist can realize the driving work of the circular ring frame 705 at this time. A rotating block 711 is fixedly installed at the other end of the screw rod 710. Anti-slip lines are provided on the outside of the rotating block 711. Rotating the rotating block 711 will drive the screw rod 710 to twist.

[0033] Refer to Figures 1-2 and Figures 4-5As shown in the figure, specifically, the scraping structure 8 includes a limiting block 83 fixedly connected to the end side of the rotating shaft 704. A rotating pin 84 is rotatably connected inside the limiting block 83. A rotating frame 81 is fixedly connected to the side wall of the rotating pin 84. Two springs 88 are fixedly connected to the bottom side of the rotating frame 81. The other ends of the two springs 88 are fixedly connected to a scraping strip 82. The scraping strip 82 is slidably connected to the inner side of the rotating frame 81. The scraping strip 82 will be closely attached to the bottom wall of the carrier 3 under the elastic force of the spring 88. At this time, the motor 707 is started to rotate, and the scraping work of the freeze-dried preparation inside the carrier 3 can be realized, which facilitates the subsequent monitoring work of other freeze-dried preparations. Four jacks 89 are evenly arranged on the surface of the rotating pin 84. A fixing block 86 is fixedly connected to the surface of the limiting block 83. A bolt 85 is threadedly connected inside the fixing block 86. The size of the bolt 85 is adapted to the size of the jack 89. By rotating the bolt 85 inside the fixing block 86 and inserting the bolt 85 into the inner side of the corresponding jack 89, the fixing work of the rotated rotating frame 81 can be realized. A rotating plate 87 is rotatably connected to the upper end of the rotating frame 81. After the rotating frame 81 rotates to a position where it is in the same straight line as the connecting strip 701, by rotating the bolt 85 inside the fixing block 86 and inserting the bolt 85 into the inner side of the corresponding jack 89, the fixing work of the rotated rotating frame 81 can be realized.

[0034] Working principle: When it is necessary to detect the moisture content of the freeze-dried preparation inside the carrier 3, after placing the freeze-dried preparation inside the carrier 3, first rotate the rotating block 711. The rotating block 711 will drive the screw rod 710 to twist. At this time, the driving work of the circular ring frame 705 can be realized. The sliding of the circular ring frame 705 on the surface of the limit pin 706 plays a role in restricting the moving direction of the circular ring frame 705. The circular ring frame 705 will drive the second comb strip 703 to extend from the upper part of the carrier 3. After placing the carrier 3 on the weighing pan 2 and covering the machine cover 4, starting the heating coil 5 can realize the evaporation and drying work of the freeze-dried preparation inside the weighing pan 2, and then realize the real-time monitoring work of the moisture content of the freeze-dried preparation. During this process, start the motor 707. The motor 707 will drive the rotating shaft 704 to rotate, and then the driving rotation work of the connecting strip 701 can be realized. The first comb strip 702 on the connecting strip 701 can not only realize the real-time spreading and stirring work of the freeze-dried preparation on the carrier 3, but also when the agglomerated freeze-dried preparation is pushed to the position of the second comb strip 703, during the process of the staggered movement between the first comb strip 702 and the second comb strip 703, the crushing work of the agglomerated freeze-dried preparation can be realized, thereby improving the evaporation efficiency of the freeze-dried preparation. After the experiment is over, after taking out the carrier 3, the second comb strip 703 can be driven to a position horizontal with the bottom side of the carrier 3, which is convenient for subsequent personnel to scrape the freeze-dried preparation adhered to the inside of the carrier 3. By setting the crushing structure 7, the flexible crushing work of the agglomerated freeze-dried preparation inside the carrier 3 is facilitated, so that the evaporation work after crushing the agglomerated freeze-dried preparation is facilitated, shortening the time for real-time monitoring of the freeze-dried preparation to a certain extent and improving the monitoring efficiency of the moisture content in the freeze-dried preparation.

[0035] After the second comb strip 703 is retracted, rotate the rotating frame 81 inside the limit block 83. When the rotating frame 81 rotates to a position on the same straight line as the connecting strip 701, rotate the bolt 85 inside the fixing block 86 and insert the bolt 85 into the corresponding jack 89, and the fixing work of the rotated rotating frame 81 can be realized. At this time, the scraping strip 82 will be tightly attached to the bottom wall of the carrier 3 under the elastic force of the spring 88. At this time, start the motor 707 to rotate, and the scraping work of the freeze-dried preparation inside the carrier 3 can be realized, which is convenient for subsequent monitoring work of other freeze-dried preparations. When it is necessary to retract the rotating frame 81, the rotating frame 81 can be flipped to a position overlapping the connecting strip 701 for fixation, and then press the scraping strip 82 to retract it inside the rotating frame 81, and then rotate the rotating plate 87 to block the end side of the scraping strip 82. At this time, the retraction work of the rotating frame 81 can be realized, which is convenient for the subsequent normal closing of the machine cover 4. By setting the scraping structure 8, the flexible scraping work of the freeze-dried preparation adhered to the inside of the carrier 3 is facilitated, and the use performance of the freeze-dried preparation moisture monitoring device is further improved.

[0036] In the description of the present utility model, it should be noted that unless otherwise clearly specified and defined, the terms "installed", "connected", and "joined" shall be understood in a broad sense. For example, it may be a fixed connection, a detachable connection, or an integral connection; it may be a mechanical connection or an electrical connection; it may be directly connected or indirectly connected through an intermediate medium, and it may be the communication inside two components. For those of ordinary skill in the art, the specific meanings of the above terms in the present utility model can be understood through specific circumstances.

Claims

1. An apparatus for online monitoring of moisture content in a freeze-dried preparation, comprising a measuring instrument (1), characterized in that: The measuring instrument (1) is provided with a weighing pan (2) mounted on the surface thereof, a frame (9) is fixedly mounted on the surface thereof, a cover (4) is rotatably mounted on the port of the frame (9), a heat insulating cover (6) is fixedly mounted on the inner side of the cover (4), a heating coil (5) is fixedly mounted on the inner side of the cover (4), a carrier (3) is placed on the surface thereof, a crushing structure (7) is provided on the surface thereof, and the crushing structure (7) comprises a roller rotatably connected to the inner side of the carrier (3) The rotating shaft (704) is fixedly connected to the side wall of the rotating shaft (704), the lower surface of the connecting strip (701) is evenly fixedly connected to a plurality of first comb strips (702), the lower surface of the carrier (3) is fixedly connected to a limit pin (706), the surface of the limit pin (706) is slidably connected to a circular frame (705), the surface of the circular frame (705) is evenly fixedly connected to a plurality of second comb strips (703), and the second comb strips (703) slide through the carrier (3).

2. The device for online monitoring of moisture content in freeze-dried preparations according to claim 1, characterized in that: Two mounting rods (709) are fixedly connected to the lower surface of the carrier (3); a mounting ring (708) is fixedly connected to one end of the two mounting rods (709) close to each other; a motor (707) is fixedly installed on the inner side of the mounting ring (708); and an output end of the motor (707) is fixedly connected to a rotating shaft (704).

3. The device for online monitoring of moisture content in freeze-dried preparations according to claim 1, characterized in that: The carrier (3) is internally rotatably connected to a screw rod (710), and the screw rod (710) is internally threadedly connected to the circular frame (705).

4. The device for online monitoring of moisture content in freeze-dried preparations according to claim 3, characterized in that: A rotating block (711) is fixedly mounted on the other end of the screw rod (710), and an anti-slip pattern is provided on the outer side of the rotating block (711).

5. The device for online monitoring of moisture content in freeze-dried preparations according to claim 1, characterized in that: The surface of the rotating shaft (704) is provided with a scraping structure (8), and the scraping structure (8) includes a limit block (83) fixedly connected to the end side of the rotating shaft (704), the inner portion of the limit block (83) is rotatably connected to a rotating pin (84), the side wall of the rotating pin (84) is fixedly connected to a rotating frame (81), the bottom side of the rotating frame (81) is fixedly connected to two springs (88), the other ends of the two springs (88) are fixedly connected to a scraping strip (82), and the scraping strip (82) is slidably connected to the inner side of the rotating frame (81).

6. The device for online monitoring of moisture content in freeze-dried preparations according to claim 5, characterized in that: Four insertion holes (89) are evenly formed on the surface of the rotation pin (84); a fixing block (86) is fixedly connected to the surface of the limit block (83); a bolt (85) is connected to the internal thread of the fixing block (86); and the size of the bolt (85) is adapted to the size of the insertion hole (89).

7. The device for online monitoring of moisture content in freeze-dried preparations according to claim 5, characterized in that: The upper end of the rotating frame (81) is rotatably connected to a rotating plate (87).

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