Liquid path system of sample analyzer and sample analyzer
By using two independent sampling needles and syringes in the urine sample analyzer, the cross-contamination problem of sample is solved, achieving high-precision and high-reliability detection effect.
Patent Information
- Application Number
- CN202421337648.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-06-11
- Publication Date
- 2025-08-05
- Estimated Expiration
- 2034-06-11
AI Technical Summary
In the existing urine sample analyzer, the two sampling needles share the same liquid path, making it difficult to clean thoroughly, resulting in cross-contamination of the samples, affecting the accuracy and credibility of the test results.
A liquid system for sample analyzer is designed, using two independent sampling needles and syringes, which are connected to the detection module through independent pipelines, and are equipped with a cleaning tank and a swab unit to achieve cleaning of the sampling needle and simplify the sample separation structure.
It avoids cross-contamination of samples, improves the accuracy and credibility of the detection results, simplifies the liquid circuit structure, and improves the detection efficiency.
Smart Images

Figure CN223192950U_ABST
Abstract
Description
Technical Field
[0001] The utility model belongs to the technical field of analysis and detection equipment, in particular to a liquid path system of a sample analyzer and the sample analyzer. Background Art
[0002] In analysis equipment such as urine sample analyzers, a sampling needle is usually provided to absorb samples. The absorbed samples are transferred to the detection module for detection and analysis. Current analysis equipment usually needs to perform multiple detection items. Currently, analyzers are usually only equipped with one sampling needle, which absorbs enough samples for each detection module to detect at one time and then divides the samples. The divided samples are respectively transferred to the corresponding detection modules to complete different detection items. The sample division is usually achieved by a sample division structure provided on the liquid path. The sample division structure is relatively complex and difficult to clean thoroughly, which can easily lead to cross-contamination of samples, affecting the accuracy and reliability of the test results. Utility Model Content
[0003] In view of the shortcomings of the prior art described above, the purpose of the present invention is to provide a liquid path system for a sample analyzer and a sample analyzer, which are used to solve the problems in the prior art where two sampling needles share the same liquid path, which is difficult to clean and easily leads to cross-contamination of samples, affecting the accuracy and reliability of the test results.
[0004] To achieve the above-mentioned and other related purposes, the present invention provides a liquid circuit system for a sample analyzer, comprising:
[0005] The first sampling needle,
[0006] A first pipeline, wherein the first pipeline is connected to the first sampling needle,
[0007] a first syringe, the first syringe being connected to the first pipeline and communicating with the first sampling needle through the first pipeline;
[0008] The second sampling needle,
[0009] A second pipeline, the second pipeline is connected to the second sampling needle,
[0010] A second syringe is connected to the second pipeline and communicated with the second sampling needle through the second pipeline.
[0011] Optionally, a cleaning tank for containing cleaning fluid is also included.
[0012] The cleaning pool is connected to a third pipeline and a fourth pipeline, the first syringe is connected to the third pipeline, the first syringe is communicated with the first sampling needle or is communicated with the cleaning pool through the third pipeline, the second syringe is connected to the fourth pipeline, the second syringe is communicated with the second sampling needle or is communicated with the cleaning pool through the fourth pipeline.
[0013] Optionally, it further comprises a first swab unit for cleaning the outer wall of the first sampling needle, wherein the first swab unit is sleeved outside the first sampling needle and is reciprocated relative to the first sampling needle along the extension direction of the first sampling needle.
[0014] The first swab unit is connected to a fifth pipeline, and the first syringe is communicated with the first sampling needle or is communicated with the first swab unit through the fifth pipeline.
[0015] Optionally, it further comprises a second swab unit for cleaning the outer wall of the second sampling needle, wherein the second swab unit is sleeved outside the second sampling needle and is arranged to reciprocate along the extension direction of the second sampling needle relative to the second sampling needle;
[0016] The second swab unit is connected to a sixth pipeline, and the second syringe is communicated with the second sampling needle or is communicated with the second swab unit through the sixth pipeline.
[0017] Optionally, the fifth pipeline is connected to an exchange pipeline connected to the second syringe, and the second syringe is communicated with the first swab unit through the exchange pipeline and the fifth pipeline.
[0018] Optionally, a first test pipeline connected to the first detection module is connected to the first pipeline between the first sampling needle and the first syringe, and the first syringe is communicated with the first detection module through the first pipeline and the first test pipeline.
[0019] Optionally, a mixing unit for supplying positive pressure gas is further included, and the mixing unit is connected to the first sampling needle.
[0020] Optionally, the mixing unit is connected to the first sampling needle through a mixing pipeline, and a mixing connecting pipeline connected to the first syringe is connected between the mixing unit and the first sampling needle.
[0021] The sample analyzer further includes a cleaning pool for containing cleaning fluid, the cleaning pool is connected to a third pipeline, and the first syringe is connected to the mixing pipeline through the mixing connecting pipeline or is connected to the cleaning pool through the third pipeline.
[0022] Optionally, a third syringe having a unit accuracy higher than that of the second syringe is further included, and the third syringe is connected to the second sampling needle.
[0023] The present invention also provides a sample analyzer, comprising the liquid path system as described in any of the above items, and also comprising a first detection module and a second detection module, wherein the first detection module is used to detect the sample collected by the first sampling needle, and the second detection module is used to detect the sample collected by the second sampling needle.
[0024] As described above, the liquid path system and sample analyzer of the present invention have the following beneficial effects: the present invention is provided with a first sampling needle and a second sampling needle, the first sampling needle is connected to the first syringe through the first pipeline, and the second sampling needle is connected to the second syringe through the second pipeline. The first sampling needle and the second sampling needle can be sampled separately without the need for sample separation or the need for setting a sample separation structure, which is conducive to avoiding cross-contamination of samples and improving the accuracy and reliability of the test results. BRIEF DESCRIPTION OF THE DRAWINGS
[0025] Figure 1 This is a schematic structural diagram of the liquid path system of the sample analyzer in an embodiment of the present utility model;
[0026] Figure 2 This is a schematic structural diagram of the first sampling needle, the second sampling needle and the transmission device in an embodiment of the present utility model;
[0027] Explanation of the accompanying drawings: first sampling needle 1, second sampling needle 2, first swab unit 3, second swab unit 4, mixing unit 5, flow pool detection device 6, cleaning pool 30, first syringe 31, second syringe 32, third syringe 33, adapter 35, waste liquid pool 39, first test pipeline 80, first pipeline 81, second pipeline 82, third pipeline 83, fourth pipeline 84, fifth pipeline 85, sixth pipeline 86, exchange pipeline 87, mixing pipeline 88, mixing connecting pipeline 89. DETAILED DESCRIPTION
[0028] The following describes the implementation of the present invention through specific embodiments. People familiar with this technology can easily understand other advantages and effects of the present invention from the contents disclosed in this specification.
[0029] See also Figures 1 to 2. It should be noted that the structures, proportions, sizes, etc. illustrated in the drawings of this specification are only used to match the contents disclosed in the specification for people familiar with this technology to understand and read, and are not used to limit the limiting conditions for the implementation of this utility model. Therefore, they have no substantive technical significance. Any modification of the structure, change in the proportional relationship or adjustment of the size should still fall within the scope of the technical content disclosed by this utility model without affecting the efficacy and purpose that can be achieved by this utility model. At the same time, the terms such as "upper", "lower", "left", "right", "middle" and "one" quoted in this specification are only for the convenience of description, and are not used to limit the scope of the implementation of this utility model. Changes or adjustments in their relative relationships should also be regarded as the scope of the implementation of this utility model without substantially changing the technical content.
[0030] See also Figure 1 This embodiment provides a fluid circuit system for a sample analyzer, including a first sampling needle, a second sampling needle, a first pipeline 81, a second pipeline 82, a first syringe 31, and a second syringe 32. The first pipeline 81 is connected to the first sampling needle 1 and the first syringe 31, respectively. The first syringe 31 communicates with the first sampling needle 1 via the first pipeline 81, allowing the first syringe 31 to aspirate a sample through the first sampling needle 1 to complete the detection of a first parameter of the sample. The second pipeline 82 is connected to the second sampling needle 2 and the second syringe 32, respectively. That is, the second syringe 32 communicates with the second sampling needle 2 via the second pipeline 82, allowing the second syringe 32 to aspirate a sample through the second sampling needle 2 to complete the detection of a second parameter of the sample.
[0031] In this embodiment, the first sampling needle 1 and the second sampling needle 2 can be sampled separately, without the need for sample splitting or the need for a sample splitting structure. This helps avoid cross-contamination of samples and improves the accuracy and reliability of the test results. At the same time, the first sampling needle 1 and the second sampling needle 2 are independently provided. Compared with a single sampling needle, the two sampling needles can move and sample independently, and the movement is more flexible. When sampling multiple samples in sequence, the samples can be sampled alternately. That is, one sample needle can be sampling while the other sample needle can be delivering samples to complete the test, thereby improving the efficiency of detection and analysis.
[0032] In this embodiment, the fluid system further includes a cleaning tank 30 for containing cleaning fluid. The cleaning tank 30 is connected to a third pipeline 83 and a fourth pipeline 84. The first sampling needle 1 is also connected to the third pipeline 83, and the second syringe 32 is also connected to the fourth pipeline 84.
[0033] The first syringe 31 can be connected to the first sampling needle 1 or to the cleaning tank 30 through the third pipeline 83. When the first syringe 31 is connected to the cleaning tank 30 through the third pipeline 83, the cleaning fluid can be drawn from the cleaning tank 30 through the third pipeline 83. When the first syringe 31 is connected to the first sampling needle 1, the sample can be drawn from the sample position through the first sampling needle 1, or the cleaning fluid in the first syringe 31 can be injected into the first sampling needle 1, thereby cleaning the inner wall of the first sampling needle 1.
[0034] The second syringe 32 can be connected to the second sampling needle 2 or to the cleaning reservoir 30 via the fourth conduit 84. When the second syringe 32 is connected to the cleaning reservoir 30 via the third conduit 83, cleaning fluid can be drawn from the cleaning reservoir 30 via the third conduit 83. The second syringe 32 is connected to the second sampling needle 2, and can draw sample from the sample site through the second sampling needle 2 or inject cleaning fluid in the second syringe 32 into the second sampling needle 2 to clean the inner wall of the second sampling needle 2.
[0035] In this embodiment, the sample analyzer also includes a first swab unit 3, which is used to clean the outer wall of the first sampling needle 1. The first swab unit 3 is sleeved outside the first sampling needle 1 and is arranged to move back and forth along the extension direction of the first sampling needle 1 relative to the first sampling needle 1. During the relative movement of the first swab unit 3 and the first sampling needle 1, the first swab unit 3 cleans the outer wall of the first sampling needle 1. In this embodiment, the first swab unit 3 is fixedly arranged on the lifting module where the first sampling needle 1 is located. The lifting module drives the first sampling needle 1 to rise and fall along the extension direction of the first sampling needle 1, thereby causing the first swab unit 3 and the first sampling needle 1 to move back and forth along the extension direction of the first sampling needle 1. During the relative movement of the first swab unit 3 and the first sampling needle 1, the first swab unit 3 cleans the outer wall of the first sampling needle 1.
[0036] Specifically, the first swab unit 3 is connected to a fifth conduit 85, the first syringe 31 is connected to the fifth conduit 85, and the first sampling needle 1 is connected to or connected to the first swab unit 3 via the fifth conduit 85. When the first syringe 31 is connected to the first swab unit 3, the first syringe 31 can draw cleaning fluid from the cleaning reservoir 30 and then inject the cleaning fluid into the first swab unit 3 through the fifth conduit 85, thereby completing the cleaning of the outer wall of the first sampling needle 1. The first swab unit 3 is also connected to a waste liquid reservoir 39, and the cleaning fluid after cleaning the outer wall of the first sampling needle 1 ultimately flows into the waste liquid reservoir 39.
[0037] In this embodiment, the sample analyzer further includes a second swab unit 4 for cleaning the outer wall of the second sampling needle 2. The second swab unit 4 is sleeved outside the second sampling needle 2 and is arranged to reciprocate relative to the second sampling needle 2 along the extension direction of the second sampling needle 2, thereby achieving cleaning of the entire outer wall of the first sampling needle 1. In this embodiment, the second swab unit 4 is fixedly mounted on a lifting module on which the second sampling needle 2 is located. The lifting module drives the second sampling needle 2 to rise and fall along the extension direction of the second sampling needle 2, thereby causing the second swab unit 4 to reciprocate with the second sampling needle 2 along the extension direction of the second sampling needle 2.
[0038] Specifically, the second swab unit 4 is connected to a sixth conduit 86, to which the second syringe 32 is connected. The second syringe 32 is in communication with the second sampling needle 2 or with the second swab unit 4 via the sixth conduit 86. When the second syringe 32 is in communication with the second swab unit 4, it draws cleaning fluid from the cleaning reservoir 30 and then injects the cleaning fluid into the second swab unit 4 via the sixth conduit 86, thereby cleaning the outer wall of the second sampling needle 2. The second swab unit 4 is also connected to a waste liquid reservoir 39, and the cleaning fluid after cleaning the outer wall of the second sampling needle 2 ultimately flows into the waste liquid reservoir 39.
[0039] In this embodiment, the fifth conduit 85 is connected to an exchange conduit 87 that communicates with the second syringe 32. The second syringe 32 communicates with the first swab unit 3 via the exchange conduit 87 and the fifth conduit 85. When the second syringe 32 communicates with the first swab unit 3 via the exchange conduit 87 and the fifth conduit 85, the second syringe 32 can draw cleaning fluid from the cleaning reservoir 30 and then inject the cleaning fluid through the exchange conduit 87 and into the first swab unit 3 via the fifth conduit 85, thereby completing the cleaning of the outer wall of the first sampling needle 1. The exchange conduit 87 allows the cleaning fluid in the second syringe 32 to flow into the first swab unit 3, thereby completing the cleaning of the first sampling needle 1 and improving the cleaning efficiency of the first sampling needle 1.
[0040] In this embodiment, a first test line 80 connected to the first detection module, i.e., the flow cell detection device 6, is connected to the first line 81 between the first sampling needle 1 and the first syringe 31. The first syringe 31 is connected to the first detection module via the first line 81 and the first test line 80. When testing the sample in the first sampling needle 1, the first syringe 31 first applies negative pressure to the first sampling needle 1 through the first line 81, causing the sample to enter the first line 81 from the first sampling needle 1 and flow through the connection between the first test line 80 and the first line 81. Then, the connection between the first sampling needle 1 and the first line 81 is disconnected, and the first syringe 31 applies positive pressure, pushing the sample in the first line 81 from the first test line 80 into the first detection module, completing the test of the first parameter of the sample.
[0041] In this embodiment, the sample analyzer further includes a mixing unit 5 for supplying positive-pressure gas. Mixing unit 5 is in communication with first sampling needle 1. After first sampling needle 1 is inserted into the sample, mixing unit 5 supplies positive-pressure gas to first sampling needle 1. After the positive-pressure gas is discharged from first sampling needle 1, bubbles are formed within the sample. The sample is mixed as the bubbles expand and collapse.
[0042] In this embodiment, the mixing unit 5 is connected to the first sampling needle 1 through the mixing pipeline 88. The mixing pipeline 88 is connected to a mixing connecting pipeline 89 connected to the first syringe 31 between the mixing unit 5 and the first sampling needle 1. The mixing connecting pipeline 89 is connected to the first syringe 31. The first syringe 31 can be connected to the mixing pipeline 88 through the mixing connecting pipeline 89, and can also be connected to the cleaning pool 30 through the third pipeline 83.
[0043] When the first syringe 31 is connected to the third pipeline 83, the first syringe 31 can draw cleaning liquid from the cleaning pool 30 through the third pipeline 83. When the first syringe 31 is connected to the mixing pipeline 88 through the mixing connecting pipeline 89, the first syringe 31 can provide negative pressure and positive pressure to the first sampling needle 1 through the mixing connecting pipeline 89 and the mixing pipeline 88, thereby aspirating and expelling the sample to complete the mixing of the sample. After the mixing is completed, the first syringe 31 can also draw cleaning liquid from the cleaning pool 30 and inject it into the mixing connecting pipeline 89 and the mixing pipeline 88, and discharge it through the first sampling needle 1, completing the cleaning of the mixing connecting pipeline 89, the mixing pipeline 88 and the inner wall of the first sampling needle 1, eliminating the residual sample in the mixing connecting pipeline 89, the mixing pipeline 88 and the inner wall of the first sampling needle 1, and avoiding cross contamination of the sample.
[0044] In this embodiment, the mixing unit 5 communicates with the mixing pipeline 88 via two parallel branches, one of which is equipped with a throttle valve. When the mixing unit 5 delivers positive-pressure gas to the first sampling needle 1 to mix the sample, the positive-pressure gas flows from the branch equipped with the throttle valve into the mixing pipeline 88. This controls the pressure of the positive-pressure gas output by the mixing unit 5 and prevents excessive pressure from ejecting the sample. When the mixing pipeline 88 is purged after cleaning, the positive-pressure gas flows from the other branch into the mixing pipeline 88 to ensure sufficient pressure.
[0045] In this embodiment, the first sampling needle 1 is connected to the adapter 35, the first pipeline 81 and the mixing pipeline 88 are both connected to the adapter 35, and then connected to the first sampling needle 1 through the adapter 35. The pipeline specifications of the first sampling needle 1 and the first pipeline 81 and the mixing pipeline 88 can be different, and they are connected to each other through the adapter 35.
[0046] In this embodiment, the analyzer also includes a third syringe 33, which has a higher unit precision than the second syringe 32. The third syringe 33 is connected to the second sampling needle 2. When the second sampling needle 2 needs to add a sample to the second detection module, the third syringe 33 provides positive pressure to the second sampling needle 2, thereby pushing the sample in the second sampling needle 2 to drip into the second detection module. The higher precision of the third syringe 33 allows for more precise control of the amount of liquid dripping from the second sampling needle 2, thereby improving detection results.
[0047] In this embodiment, pressure sensors are provided at the outlets of the first syringe 31 and the second syringe 32, which are used to detect the pressure at the outlets of the first syringe 31 and the second syringe 32 respectively. When the pressure at the outlet of the first syringe 31 or the second syringe 32 exceeds the preset patency threshold, it can be determined that there is a blockage in the corresponding connected pipeline.
[0048] See also Figure 2 This embodiment provides a sample analyzer comprising the aforementioned fluidic system, a first detection module, a second detection module, and a transmission device 40. The transmission device 40 is capable of driving the first sampling needle 1 and the second sampling needle 2 to move, respectively. The first detection module is capable of detecting a first parameter of the sample, and the second detection module is capable of detecting a second parameter of the sample.
[0049] The sample analyzer further comprises a sample dropping position and a sample aspirating position, both of which are located on the moving path of the second sampling needle 2. Meanwhile, the sample aspirating position is also located on the moving path of the first sampling needle 1.
[0050] In existing technology, devices such as urine sample analyzers typically include a sampling needle. Some analytical devices also feature both a sampling needle and a sample dropper, with the sampling needle used for sample aspiration and the sample dropper used for sample droppering. The sampling needle simultaneously draws sufficient sample for various testing modules, such as dry chemistry and morphology, to analyze the sample for different analyses, reducing the number of sample draws and improving testing efficiency. After sample aspiration, the sample must be split, increasing the sample splitting mechanism and the risk of cross-contamination due to the complex and difficult-to-clean fluid flow path of the device.
[0051] like Figure 1 As shown, in this embodiment, the sample analyzer is provided with two sampling needles, which can respectively take samples at the sample position and transmit the samples to the corresponding detection modules respectively. There is no need to separate the samples or set up a sample separation structure, which simplifies the liquid path, helps to reduce the chance of sample cross-contamination, and improves the accuracy and reliability of the detection results.
[0052] Specifically, in this embodiment, the first detection module is a flow cell detection device 6, and the second detection module is a test strip detection device. The test strip detection device is used for dry chemical analysis of urine. Urine dry chemical analysis is called urine test strip measurement. The test strip is composed of a module containing dry chemical reagents attached to a sturdy plastic strip or paper strip. Various routine chemical examination contents in the urine sample react with the dry chemical reagents, causing the color of the module on the test strip to change. The depth of its color is proportional to the concentration of the corresponding chemical component in the urine sample. The flow cell detection device 6 is used for morphological testing of urine. Urine formed elements refer to the general term for substances that come from the urinary tract and are formed by seepage, excretion, shedding and concentrated crystallization in a visible form. The urine sample passes through the flow cell, and images of the formed elements in the urine are obtained using equipment such as a microscope, and then identified and counted to obtain the detection and analysis results.
[0053] Specifically, the sample analyzer also has a first cleaning position and a second cleaning position. The first cleaning position is located on the moving path of the first sampling needle 1, and the second cleaning position is located on the moving trajectory of the second sampling needle 2. The first cleaning position and the sample suction position are arranged at a distance. When the first sampling needle 1 is cleaned at the first cleaning position, the sample position is vacant, which facilitates the second sampling needle 2 to move to the sample position for sample suction. The second cleaning position is located between the sample suction position and the sample dripping position, which facilitates the cleaning of the second sampling needle 2 in the process of the sample dripping back to the sample suction position for the next sample suction, saving time and improving detection efficiency. In this embodiment, the first cleaning position and the second cleaning position are respectively provided with a waste liquid pool 39, which are used to collect the waste liquid generated by the cleaning of the first sampling needle 1 and the second sampling needle 2, respectively.
[0054] During the actual sample analysis process, the first sampling needle 1 first moves along the guide rail to the sample position, then descends and extends into the sample to mix the sample. Specifically, when the first sampling needle 1 mixes the sample, the first syringe 31 first communicates with the first sampling needle 1 through the mixing connection line 89 and the mixing line 88. The first syringe 31 alternately generates negative pressure and positive pressure, causing the first sampling needle 1 to aspirate and exhale the sample, completing the aspiration and exhalation mixing of the sample. Subsequently, the mixing unit 5 communicates with the first sampling needle 1 through the mixing line 88. The mixing unit 5 provides positive pressure gas, which is discharged into the sample by the first sampling needle 1 to form bubbles. The bubbles mix the sample during the discharge process.
[0055] The first sampling needle 1 aspirates and exhales the sample to mix it. When the first syringe 31 generates positive pressure, the first syringe 31 is connected to the flow cell detection device 6 through the first pipeline 81 and the first test pipeline 80. The cleaning liquid in the first syringe 31 is injected into the flow cell detection device 6 to flush the flow cell detection device 6.
[0056] After the mixing is completed, the first sampling needle 1 samples the mixed sample. The first syringe 31 is first connected to the first sampling needle 1 through the mixing connecting pipe 89 and the mixing pipe 88. The first syringe 31 generates negative pressure, and the mixed sample flows into the first pipe 81 through the first sampling needle 1 until the sample amount flowing through the connection between the first test pipe 80 and the first pipe 81 meets the test requirement of the first detection module, that is, the flow cell detection device 6.
[0057] During the sampling process of the first sampling needle 1 , when the first syringe 31 generates negative pressure, the first syringe 31 is connected to the cleaning tank 30 through the third pipeline 83 , and the cleaning fluid is drawn from the cleaning tank 30 to complete the fluid replenishment.
[0058] After the first sampling needle 1 completes sampling, the first sampling needle 1 rises to separate from the sample. After the first sampling needle 1 rises to its proper position, it moves to the first cleaning position.
[0059] At the same time, the first pipeline 81 is disconnected from the first sampling needle 1, the first test pipeline 80 is connected to the first pipeline 81, the first syringe 31 generates positive pressure, and the sample in the first pipeline 81 between the connection between the first test pipeline 80 and the first pipeline 81 and the first syringe 31 is sent into the first detection module under the action of the first syringe 31 for morphological testing.
[0060] At the same time, before the first sampling needle 1 reaches the first cleaning position, the first sampling needle 1 and the first swab unit 3 move relative to each other via the lifting module. The first syringe 31 generates positive pressure, causing the cleaning fluid in the first syringe 31 to be injected into the first swab unit 3 through the fifth pipeline 85. During the relative movement between the first sampling needle 1 and the first swab unit 3, the first swab unit 3 cleans the outer wall of the first sampling needle 1.
[0061] After the first sampling needle 1 moves to the first cleaning position, the first syringe 31 is connected to the first sampling needle 1 through the first pipeline 81. The first syringe 31 generates positive pressure, and the cleaning liquid in the first syringe 31 flows into the first sampling needle 1 through the first pipeline 81 and is discharged from the first sampling needle 1, completing the cleaning of the first pipeline 81 and the inner wall of the first sampling needle 1. After the inner wall of the first sampling needle 1 is cleaned, the first syringe 31 is connected to the mixing connecting pipeline 89 and the mixing pipeline 88. The first syringe 31 generates positive pressure, and the cleaning liquid in the first syringe 31 flows into the first sampling needle 1 through the mixing connecting pipeline 89 and the mixing pipeline 88 and is discharged from the first sampling needle 1, completing the cleaning of the mixing pipeline 88 and the inner wall of the first sampling needle 1.
[0062] After the mixing pipeline 88 is cleaned, the mixing unit 5 is connected to the mixing pipeline 88, and the positive pressure gas supplied by the mixing unit 5 is blown out through the mixing pipeline 88 and the first sampling needle 1, thereby blowing out the mixing pipeline 88 and the first sampling needle 1, thereby improving the cleaning effect of the mixing pipeline 88 and the first sampling needle 1.
[0063] After the first sampling needle 1 leaves the sample position, the second sampling needle 2 moves to the sample position. The second sampling needle 2 descends under the action of the lifting module and enters the sample to sample the mixed sample.
[0064] The second syringe 32 is connected to the second sampling needle 2 via the second conduit 82. The second syringe 32 generates negative pressure, causing the second sampling needle 2 to draw sample until the sample volume meets the requirements of the first detection module. Simultaneously, the second syringe 32 is connected to the cleaning reservoir 30 via the fourth conduit 84 to draw cleaning fluid.
[0065] After the second sampling needle 2 completes sampling, the lifting module corresponding to the second sampling needle 2 drives the second sampling needle 2 upward, allowing the second sampling needle 2 to move toward the sample dripping position. Before the second sampling needle 2 moves to the sample dripping position, the second syringe 32 is connected to the second swab unit 4 via the sixth pipeline 86. The second syringe 32 is disconnected from the second sampling needle 2, generating positive pressure in the second syringe 32. The cleaning fluid in the second syringe 32 flows through the sixth pipeline 86 into the second swab unit 4, cleaning the outer wall of the second sampling needle 2.
[0066] After the second sampling needle 2 moves to the sample dripping position, the third syringe 33 is connected to the second sampling needle 2 through the second pipeline 82. The third syringe 33 generates positive pressure. Under the action of the third syringe 33, the sample drips out through the second sampling needle 2 and drips into the second detection module, that is, the test strip detection device. The test strip detection device detects the sample.
[0067] After the second sampling needle 2 completes sample dripping, it moves to the second cleaning position. After the second sampling needle 2 moves to the cleaning position, the second syringe 32 is connected to the second sampling needle 2 through the second pipeline 82. The second syringe 32 generates positive pressure, and the cleaning liquid in the second syringe 32 flows into the second sampling needle 2 through the second pipeline 82 and flows out of the second sampling needle 2, completing the cleaning of the second pipeline 82 and the inner wall of the second sampling needle 2.
[0068] The inner and outer walls of the first sampling needle 1 and the second sampling needle 2 are cleaned separately, which is conducive to the reasonable arrangement of the cleaning sequence of the first sampling needle 1 and the second sampling needle 2, reduces the overall analysis time of the sample, and improves the sample analysis efficiency.
[0069] The above embodiments are merely illustrative of the principles and effects of the present invention and are not intended to limit the present invention. Anyone skilled in the art may modify or alter the above embodiments without departing from the spirit and scope of the present invention. Therefore, all equivalent modifications or alterations made by one of ordinary skill in the art without departing from the spirit and technical principles disclosed in the present invention are intended to be covered by the claims of the present invention.
Claims
1. A liquid path system of a sample analyzer, characterized in that: include: The first sampling needle, A first pipeline, wherein the first pipeline is connected to the first sampling needle, a first syringe, the first syringe being connected to the first pipeline and communicating with the first sampling needle through the first pipeline; The second sampling needle, A second pipeline, the second pipeline is connected to the second sampling needle, A second syringe is connected to the second pipeline and communicated with the second sampling needle through the second pipeline.
2. The fluid circuit system according to claim 1, characterized in that: It also includes a cleaning tank for holding cleaning fluid. The cleaning pool is connected to a third pipeline and a fourth pipeline, the first syringe is connected to the third pipeline, the first syringe is communicated with the first sampling needle or is communicated with the cleaning pool through the third pipeline, the second syringe is connected to the fourth pipeline, the second syringe is communicated with the second sampling needle or is communicated with the cleaning pool through the fourth pipeline.
3. The liquid path system of the sample analyzer according to claim 1 or 2, characterized in that: The apparatus further comprises a first swab unit for cleaning the outer wall of the first sampling needle. The first swab unit is sleeved outside the first sampling needle and is reciprocated relative to the first sampling needle along the extension direction of the first sampling needle. The first swab unit is connected to a fifth pipeline, and the first syringe is communicated with the first sampling needle or is communicated with the first swab unit through the fifth pipeline.
4. The liquid path system of the sample analyzer according to claim 1 or 2, characterized in that: It also includes a second swab unit for cleaning the outer wall of the second sampling needle, the second swab unit is sleeved outside the second sampling needle, and is arranged to move back and forth relative to the second sampling needle along the extension direction of the second sampling needle; The second swab unit is connected to a sixth pipeline, and the second syringe is communicated with the second sampling needle or is communicated with the second swab unit through the sixth pipeline.
5. The liquid path system of the sample analyzer according to claim 3, characterized in that: The fifth pipeline is connected to an exchange pipeline connected to the second syringe, and the second syringe is communicated with the first swab unit through the exchange pipeline and the fifth pipeline.
6. The liquid path system of the sample analyzer according to claim 1, characterized in that: A first test pipeline connected to the first detection module is connected to the first pipeline between the first sampling needle and the first syringe. The first syringe is communicated with the first detection module through the first pipeline and the first test pipeline.
7. The liquid path system of the sample analyzer according to claim 1, characterized in that: It also includes a mixing unit for supplying positive pressure gas, and the mixing unit is connected to the first sampling needle.
8. The liquid path system of the sample analyzer according to claim 7, characterized in that: The mixing unit is connected to the first sampling needle through a mixing pipeline, and a mixing connection pipeline connected to the first syringe is connected between the mixing unit and the first sampling needle. The sample analyzer further includes a cleaning pool for containing cleaning fluid, the cleaning pool is connected to a third pipeline, and the first syringe is connected to the mixing pipeline through the mixing connecting pipeline or is connected to the cleaning pool through the third pipeline.
9. The liquid path system of the sample analyzer according to claim 1, characterized in that: The invention also includes a third syringe having a unit accuracy higher than that of the second syringe, and the third syringe is connected to the second sampling needle.
10. A sample analyzer, characterized in that: The liquid circuit system comprises the liquid circuit system according to any one of claims 1 to 9, further comprising a first detection module and a second detection module, wherein the first detection module is used to detect the sample collected by the first sampling needle, and the second detection module is used to detect the sample collected by the second sampling needle.