Storage device for collecting gynecological tumor specimens

By designing a storage device for gynecological tumor specimens, using the through-tube and sealing cover plate to form a closed environment, the vacuum tube creates a vacuum state, solving the problem of cell necrosis caused by uneven cooling in the prior art, and achieving stable preservation of the specimen.

CN223195412UActive Publication Date: 2025-08-08THE FOURTH HOSPITAL OF HEBEI MEDICAL UNIVERSITY (HEBEI CANCER HOSPITAL)
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Patent Information

Application Number
CN202422438495.8
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-10-10
Publication Date
2025-08-08
Estimated Expiration
2034-10-10

AI Technical Summary

Technical Problem

The existing gynecological tumor specimens are poorly sealed when stored, resulting in uneven cooling and direct contact with low temperatures to lead to necrosis.

Method used

A storage device for gynecological tumor specimens collection is designed, including storage plates, splints and sealing cover plates. Cooling protective agent is input through the through-tube, and sealing cover plates are used to form a sealed and sealed environment. The vacuum tube creates a vacuum state to ensure that the tumor specimens are stored separately in the cavity of the tissue section and avoid direct contact with external coolant.

Benefits of technology

It achieves uniform cooling and cooling of tumor specimens, avoids cell frostbite, provides stable storage protection, and ensures good storage of specimens.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a storage device for collecting gynecological tumor specimens, which comprises a storage plate, a placing groove is arranged on the upper surface of the storage plate, through holes are arranged in the left side and the right side of the storage plate, through pipes are arranged on the inner sides of the through holes, a clamping plate is arranged on the inner side of the placing groove, and the clamping plate is arranged on the inner side of the clamping plate. A tissue slice containing cavity is fixedly formed in the center of the upper surface of the clamping plate, a clamping sleeve is fixed to the center of the lower surface of the clamping plate, a sealing cover plate is arranged above the clamping plate, and a surrounding cavity is fixed to the middle of the lower surface of the sealing cover plate; the clamping plates can be tightly pressed by the sealing cover plates, and a sealed environment is formed in the tissue section containing cavity, so that the tumor specimens are independently stored in the tissue section containing cavity and are not in direct contact with an externally filled cooling protective agent, cell frostbite and necrosis are avoided, meanwhile, the tumor specimens are independently placed in the tissue section containing cavity, and the tumor specimens are prevented from being damaged. And uniform cooling treatment can be obtained.
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Description

Technical Field

[0001] The utility model relates to the technical field of gynecological tumor specimen storage, in particular to a storage device for collecting gynecological tumor specimens. Background Art

[0002] Programmed cooling is also called slow cooling low-temperature preservation. Taking cells as an example, the cells are first slowly cooled to a certain temperature in a solution containing a cryoprotectant, and then quickly cooled to liquid nitrogen temperature for long-term storage. This process ultimately achieves partial crystallization and vitrification, that is, there are crystals outside the cells and the intracellular solution reaches vitrification. Tissue specimens stored in tumor tissue banks are no larger than soybeans. According to past experience, programmed cooling is suitable for use. Gynecological tumor specimens belong to a large category of tumor tissue banks and are of great significance to gynecological tumor research.

[0003] Existing gynecological tumor specimens are not well sealed during storage. Tumor sections are generally placed on glass slides, and a glass press is placed on the slide. There is a gap between the two glass slides, and the outside air will come into direct contact with the tissue sections. During cooling, because the tumor sections are in direct contact with the cryoprotectant, there is a problem of uneven temperature during cooling. The low temperature directly acts on the cells, causing direct cell necrosis, which can easily lead to problems in the cryopreservation of tumor sections.

[0004] Therefore, those skilled in the art provide a storage device for collecting gynecological tumor specimens to solve the problems raised in the above background technology. Utility Model Content

[0005] The purpose of the present utility model is to provide a storage device for collecting gynecological tumor specimens, so as to solve the problem of poor airtightness of the existing gynecological tumor specimens during storage, as mentioned in the above background technology.

[0006] To achieve the above objectives, the present invention provides the following technical solutions:

[0007] A storage device for collecting gynecological tumor specimens comprises: a storage plate, the upper surface of the storage plate is provided with a placement groove, and the bottom center of the placement groove is provided with a locking groove, the left and right sides of the storage plate are penetrated by through holes, and the inner sides of the through holes are installed with through tubes, the inner side of the placement groove is installed with a splint, and a vacuum tube is fixedly penetrated through the middle of the splint, a tissue section cavity is fixedly provided with a tissue section cavity in the center of the upper surface of the splint, and a pressing sheet is fixed equidistantly above the edge of the splint, a locking sleeve is fixed at the center of the lower surface of the splint, and the locking sleeve is assembled on the inner side of the locking groove, a sealing cover is provided above the splint, and an enclosing cavity is fixed in the middle of the lower surface of the sealing cover, the enclosing cavity is tightly fitted to the outer side of the tissue section cavity, and a leveling sponge is fixed to the lower surface of the sealing cover and on the inner side of the enclosing cavity.

[0008] As a solution in the present invention, through grooves are symmetrically provided on the left and right sides of the side walls of the placement groove, and the through grooves are respectively connected to the through holes.

[0009] As a solution in the present invention, both ends of the through pipe are fixedly connected with connecting pipe openings, and a groove is opened on one side of the through pipe close to the vertical center line of the storage plate.

[0010] As a solution of the present invention, a vacuum hole is passed through the center of the inner bottom surface of the engaging groove, and clamping columns are evenly fixed around the vacuum hole and on the inner bottom surface of the engaging groove.

[0011] As a solution in the present invention, a clamping sleeve is fixed on the inner side of the clamping sleeve and around the lower surface of the clamping plate at equal distances, and the positions of the clamping sleeve and the clamping column correspond one to one, and the sizes of the clamping sleeve and the clamping column are consistent.

[0012] As a solution in the present invention, the vacuum tube coaxially passes through the center of the clamping plate, and the vacuum tube passes through the inside of the vacuum hole.

[0013] Compared with the prior art, the beneficial effects of the present invention are:

[0014] 1. The sealing cover can be used to compress the splint and form a sealed environment inside the tissue section cavity. In this way, the tumor specimen is stored separately in the tissue section cavity and does not come into direct contact with the cooling protective agent filled from the outside, thus avoiding cell frostbite and necrosis. At the same time, the tumor specimen is placed separately in the tissue section cavity and can be evenly cooled.

[0015] 2. The splint is fixed to the storage plate through the cooperation of the snap-fit groove and the snap-fit sleeve, and the clamping column and the clamping sleeve, and is placed stably, which can provide good and stable storage protection for the tumor specimens inside. The vacuum tube can extract the air in the tissue section cavity, making the interior of the tissue section cavity a vacuum environment, so as to better store the tumor specimens inside.

[0016] 3. The through-tube forms a communicating structure with the placement slot through the through-slot, and the cooling protective agent input into the through-tube can enter the placement slot from the through-slot and directly act on the splint, thereby cooling the tumor specimen placed in the splint and making the cooling uniform. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 This is a schematic diagram of the explosion structure of a storage device for collecting gynecological tumor specimens.

[0018] Figure 2 This is a schematic diagram of the overall structure of a storage device for collecting gynecological tumor specimens.

[0019] Figure 3 This is a schematic diagram of the partial structure of a through-tube in a storage device for collecting gynecological tumor specimens.

[0020] Figure 4 A storage device for collecting gynecological tumor specimens Figure 1 Enlarged structural diagram at point A in the middle.

[0021] Figure 5 This is a schematic diagram of the upper structure of a splint in a storage device for collecting gynecological tumor specimens.

[0022] Figure 6 This is a schematic diagram of the lower structure of a splint in a storage device for collecting gynecological tumor specimens.

[0023] Figure 7 This is a schematic diagram of the lower structure of a sealing cover in a storage device for collecting gynecological tumor specimens.

[0024] In the figure: 1. Storage plate; 2. Placement slot; 3. Through slot; 4. Clamping slot; 5. Clamping column; 6. Vacuum hole; 7. Through hole; 8. Through pipe; 9. Connecting pipe mouth; 10. Cutting groove; 11. Clamping plate; 12. Vacuum tube; 13. Tissue section cavity; 14. Pressing plate; 15. Clamping sleeve; 16. Clamping sleeve; 17. Sealing cover plate; 18. Surrounding cavity; 19. Leveling sponge. DETAILED DESCRIPTION

[0025] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0026] See also Figures 1 to 7 The embodiment of the present invention provides a storage device for collecting gynecological tumor specimens, comprising: a storage plate 1, a storage groove 2 is provided on the upper surface of the storage plate 1, and a locking groove 4 is provided at the bottom center of the storage groove 2, through holes 7 are penetrated inside the left and right sides of the storage plate 1, and through pipes 8 are installed inside the through holes 7, through grooves 3 are symmetrically provided on the left and right sides of the side walls of the storage groove 2, and the through grooves 3 are respectively connected to the through holes 7, both ends of the through pipe 8 are fixedly connected to the connecting pipe opening 9, and a cutting groove 10 is opened on the side of the through pipe 8 close to the vertical center line of the storage plate 1;

[0027] Specifically, the through-tube 8 is installed in the through-hole 7. The slots 10 on the through-tube 8 are connected to the through-slots 3 under the communication function of the through-hole 7. In this way, the through-tube 8 can form a communication structure with the placement tank 2 through the through-slots 3. The cooling protective agent input into the through-tube 8 can enter the placement tank 2 through the through-slots 3 and directly act on the splint 11 in the placement tank 2, thereby cooling the tumor specimen placed in the splint 11 and achieving uniform cooling.

[0028] A splint 11 is installed on the inner side of the placement groove 2, and a vacuum tube 12 is fixedly passed through the middle of the splint 11, a tissue slice cavity 13 is fixedly provided at the center of the upper surface of the splint 11, and a pressing piece 14 is fixed equidistantly above the edge of the splint 11, a clamping sleeve 15 is fixed at the center of the lower surface of the splint 11, and the clamping sleeve 15 is assembled on the inner side of the clamping groove 4, a vacuum hole 6 is passed through the center of the inner bottom surface of the clamping groove 4, and a clamping column 5 is evenly fixed around the vacuum hole 6 and on the inner bottom surface of the clamping groove 4, a clamping sleeve 16 is fixed on the inner side of the clamping sleeve 15 and around the lower surface of the splint 11 at an equal distance, and the position of the clamping sleeve 16 and the clamping column 5 correspond one to one, and the size of the clamping sleeve 16 and the clamping column 5 are consistent, the vacuum tube 12 passes through the center of the splint 11 coaxially, and the vacuum tube 12 passes through the inside of the vacuum hole 6;

[0029] Specifically, the tissue slice cavity 13 in the splint 11 is used to store tumor specimens. A snap-fit sleeve 15 and a snap-fit sleeve 16 are provided at the bottom of the splint 11, which match the size of the snap-fit groove 4 and the clamping column 5 in the snap-fit groove 4. These are used to secure the splint 11 to the storage plate 1, ensuring that the splint 11 is stably placed and providing good and stable storage protection for the tumor specimen therein. The top of the vacuum tube 12 extends into the tissue slice cavity 13 to extract air from the tissue slice cavity 13, creating a vacuum environment inside the tissue slice cavity 13 to better store the tumor specimen therein.

[0030] A sealing cover plate 17 is provided above the clamping plate 11, and a surrounding cavity 18 is fixed in the middle of the lower surface of the sealing cover plate 17. The surrounding cavity 18 is closely attached to the outside of the tissue slice cavity 13, and a leveling sponge 19 is fixed on the lower surface of the sealing cover plate 17 and inside the surrounding cavity 18.

[0031] Specifically, the sealing cover 17 is pressed against the clamping plate 11 by the pressing sheet 14. The surrounding cavity 18 on the bottom surface of the sealing cover 17 can tightly wrap the tissue slice cavity 13 to form a sealed and closed environment. The leveling sponge 19 is used to press and fix the tumor specimen so that the tumor specimen is flattened and spread out in the tissue slice cavity 13, thereby being evenly cooled.

[0032] The working principle of this utility model is:

[0033] First, the storage device is assembled. Specifically, the through-tube 8 is inserted into the through-hole 7. The clamping plate 11 is fixed to the corresponding placement groove 2 on the storage plate 1. The sealing cover 17 is then removed. The prepared tumor specimen is placed in the tissue slice cavity 13 and spread out flat. The sealing cover 17 is then replaced on the clamping plate 11 and pressed and fixed with the pressing plate 14. The surrounding cavity 18 tightly surrounds the tissue slice cavity 13, thus sealing the interior of the tissue slice cavity 13. The air in the tissue slice cavity 13 is then extracted through the vacuum tube 12, creating a vacuum state inside the tissue slice cavity 13. The tumor specimen is now well preserved in the tissue slice cavity 13. Finally, a cooling agent is injected into the through-tube 8 through the connecting pipe 9. Through the connection structure of the cutting groove 10 and the through-slot 3, the cooling agent eventually enters the placement groove 2 and directly contacts the clamping plate 11, thereby cooling the tumor specimen in the clamping plate 11.

[0034] The above is only a preferred specific implementation method of the present invention, but the protection scope of the present invention is not limited to this. Any technician familiar with the technical field within the technical scope disclosed by the present invention can make equivalent replacements or changes based on the technical solution and utility model concept of the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A storage device for collecting gynecological tumor specimens, characterized in that: include: A storage plate (1), wherein a storage groove (2) is provided on the upper surface of the storage plate (1), and a locking groove (4) is provided at the bottom center of the storage groove (2), through holes (7) are passed through the inside of the left and right sides of the storage plate (1), and through tubes (8) are installed on the inner sides of the through holes (7), a splint (11) is installed on the inner side of the storage groove (2), and a vacuum tube (12) is fixedly passed through the middle of the splint (11), a tissue slice cavity (13) is fixedly provided at the center of the upper surface of the splint (11), and the splint (11) A pressing sheet (14) is fixed at an equal distance above the edge of the splint (11), a snap-fit sleeve (15) is fixed at the center of the lower surface of the splint (11), and the snap-fit sleeve (15) is assembled on the inner side of the snap-fit groove (4), a sealing cover (17) is provided above the splint (11), and an enclosing cavity (18) is fixed in the middle of the lower surface of the sealing cover (17), the enclosing cavity (18) is closely attached to the outer side of the tissue slice cavity (13), and a leveling sponge (19) is fixed on the lower surface of the sealing cover (17) and on the inner side of the enclosing cavity (18).

2. A storage device for collecting gynecological tumor specimens according to claim 1, characterized in that: Through grooves (3) are symmetrically provided on the left and right sides of the side walls of the placement groove (2), and the through grooves (3) are respectively connected to the through holes (7).

3. The storage device for collecting gynecological tumor specimens according to claim 1, characterized in that: Both ends of the through-tube (8) are fixedly connected to connecting pipe openings (9), and a groove (10) is provided on one side of the through-tube (8) close to the vertical center line of the storage plate (1).

4. The storage device for collecting gynecological tumor specimens according to claim 1, characterized in that: A vacuum hole (6) is provided through the center of the inner bottom surface of the clamping groove (4), and clamping columns (5) are evenly fixed around the vacuum hole (6) and on the inner bottom surface of the clamping groove (4).

5. The storage device for collecting gynecological tumor specimens according to claim 4, characterized in that: A clamping sleeve (16) is fixed on the inner side of the clamping sleeve (15) and around the lower surface of the clamping plate (11) at equal distances, and the positions of the clamping sleeve (16) and the clamping column (5) correspond one to one, and the sizes of the clamping sleeve (16) and the clamping column (5) are consistent.

6. The storage device for collecting gynecological tumor specimens according to claim 4, characterized in that: The vacuum tube (12) coaxially passes through the center of the clamping plate (11), and the vacuum tube (12) passes through the inside of the vacuum hole (6).