High-precision digital slice Z-axis light path system based on rotary imaging
By setting the camera, barrel mirror, fluorescence mechanism, panoramic camera and lifting lens on the same axis on the vertical plate, forming a Z-axis optical path, solving the problems of low imaging accuracy and efficiency of existing equipment, and achieving efficient switching and high-precision imaging of multiple imaging modes.
Patent Information
- Application Number
- CN202421653415.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-12
- Publication Date
- 2025-08-08
- Estimated Expiration
- 2034-07-12
AI Technical Summary
The existing digital slice fast scanning equipment has complex structural design, and the dispersed arrangement of each component leads to low imaging accuracy and efficiency.
The camera, barrel mirror, fluorescence mechanism, panoramic camera, lifting lens and a complete set of light sources are arranged in turn on the vertical axis direction on the same side of the vertical plate to form a Z-axis light path. The fluorescence mechanism includes a rotatable turntable and a rotating slide table to achieve switching of multiple imaging modes.
The imaging accuracy and efficiency are improved, panoramic, dual-channel fluorescence and white light field imaging are achieved, the structural layout is reasonable, and the coordination of each component is better.
Smart Images

Figure CN223205346U_ABST
Abstract
Description
Technical Field
[0001] The utility model belongs to the technical field of digital slice scanning imaging equipment, and more specifically relates to a high-precision digital slice Z-axis optical path system based on rotational imaging. Background Art
[0002] The high-precision digital slide intelligent scanner is a high-end instrument that can quickly and accurately obtain microscopic tissue structure information. Its primary purpose is to achieve high-fidelity restoration of tissue slide images, improve scanning speed and automation, optimize the digital slide scanner's operating system and software, and enable intelligent operation and data management. It has broad application prospects in fields such as materials science, biology, and medicine.
[0003] The Z-axis optical path in the high-precision digital slide intelligent scanner is the key to the visual scanning of the entire high-precision digital slide fast scanner. The existing digital slide fast scanning equipment has a complex structural design and the components are arranged in a scattered manner, which makes the coordination efficiency of the components low, resulting in the problem of low final imaging accuracy.
[0004] It can be seen that how to provide a device with a reasonable design to improve the accuracy of switching between multiple imaging modes is a technical problem that those skilled in the art urgently need to solve. Utility Model Content
[0005] In view of the above defects or improvement needs of the prior art, in a first aspect, the present invention provides a high-precision digital slice Z-axis optical path system based on rotational imaging, comprising:
[0006] A vertical plate, on the same side of which a camera, a tube lens, a fluorescent mechanism, a panoramic camera, a lifting lens and a complete set of light sources are sequentially arranged in the vertical axis direction to form a Z-axis optical path;
[0007] The cylindrical mirror is arranged on the upper side wall of the vertical plate, and the upper end of the cylindrical mirror is connected to the camera; the fluorescent mechanism is arranged on the middle side wall of the vertical plate, and the fluorescent mechanism is directly opposite to the lower end of the cylindrical mirror, and the panoramic camera is arranged on the side of the fluorescent mechanism; the lifting lens and the entire set of light sources are arranged in sequence on the lower side wall of the vertical plate;
[0008] Wherein, the fluorescent mechanism includes a rotatable turntable, a plurality of fluorescent components are provided on the turntable, and the rotation path of the turntable passes through the lower end portion of the tube mirror in sequence.
[0009] In the first aspect, the fluorescent mechanism further includes a rotating slide, one end of which is rotatably mounted on the vertical plate, and the turntable is rotatably mounted on the upper surface of the rotating slide.
[0010] In the first aspect, the turntable is disc-shaped, and a plurality of mounting areas with equal angles are evenly arranged based on the center of the disc-shaped turntable, and each mounting area is provided with a fluorescent component.
[0011] In a first aspect, the fluorescent assembly comprises:
[0012] a fixed block having a first space and a second space, wherein an outlet of the first space is connected to an inlet of the second space;
[0013] The first space is horizontally provided with a lamp bead, a pair of collimating lenses and a retaining ring arranged between the pair of collimating lenses in sequence;
[0014] The second space is provided with a pair of filters and a semi-transparent filter arranged between the pair of filters. The pair of filters are correspondingly located at the inlet and outlet of the second space, and the outlet of the second space is directly opposite to the lower end of the tube mirror.
[0015] In the first aspect, the fluorescent assembly further includes a heat sink disposed in the first space, and the heat sink is attached to the lamp bead.
[0016] In the first aspect, the fluorescent assembly further includes a baffle, which is disposed between the first space and the second space and is made of a transparent material.
[0017] In the first aspect, the system further comprises a semi-frame box structure; the semi-frame box structure is provided on the vertical plate and is located between the cylindrical mirror and the lifting lens;
[0018] The semi-frame box structure has a accommodating space and a pair of openings that are adjacent to and connected to the accommodating space, one of the openings is located on the connection side with the vertical plate, and the other opening is used to accommodate part of the structure of the fluorescent mechanism. A pair of symmetrical through holes are also provided on a pair of opposite side surfaces of the semi-frame box structure, and a pair of the through holes are located between the barrel mirror and the lifting lens.
[0019] In the first aspect, the outer side wall of the semi-frame box is provided with an L-shaped connecting plate, one side plate of the L-shaped connecting plate is connected to the outer side wall of the semi-frame box, and the other side plate is used to connect the panoramic camera.
[0020] In the first aspect, the system further includes a light source, which is provided on another side plate of the L-shaped connecting plate and arranged parallel to the panoramic camera.
[0021] In the first aspect, the lifting lens includes a single lens or multiple lenses.
[0022] In general, the above technical solutions conceived by the present invention can achieve the following beneficial effects compared with the prior art:
[0023] 1. The high-precision digital slice Z-axis optical path system based on rotational imaging of the present invention forms a Z-axis optical path for imaging by arranging a camera, a tube lens, a fluorescent mechanism, a panoramic camera, a lifting lens and a complete set of light sources in sequence on the same side of the vertical axis of the vertical plate. By utilizing the above-mentioned structures, three different imaging modes can be achieved, namely, panoramic imaging can be achieved by utilizing a panoramic camera; dual-channel fluorescent imaging or monochrome fluorescent imaging can be achieved by utilizing a camera, a tube lens and a fluorescent mechanism; and white light bright field imaging can be achieved by moving the fluorescent mechanism out of the optical path and illuminating with white light from the complete set of light sources.
[0024] 2. By arranging the camera, tube lens, fluorescent mechanism, panoramic camera, lifting lens and a complete set of light sources on the same axis, the structural layout is reasonable, which makes the coordination of various components better, thereby ensuring higher final imaging accuracy and higher imaging efficiency. BRIEF DESCRIPTION OF THE DRAWINGS
[0025] Figure 1 This is a schematic structural diagram of a high-precision digital slice Z-axis optical path system based on rotational imaging in an embodiment of the present invention;
[0026] Figure 2 This is a partial schematic diagram of the Z-axis optical path system of a high-precision digital slice based on rotational imaging in an embodiment of the present utility model;
[0027] Figure 3 The structure of the fluorescent component in the embodiment of the utility model is shown as follows Figure 1 ;
[0028] Figure 4 The structure of the fluorescent component in the embodiment of the utility model is shown as follows Figure 2 ;
[0029] Figure 5 The structure diagram of the lifting lens in the embodiment of the utility model is shown as follows: Figure 1 ;
[0030] Figure 6 The structure diagram of the lifting lens in the embodiment of the utility model is shown as follows: Figure 2 .
[0031] Description of reference numerals:
[0032] 1. Vertical board;
[0033] 2. Camera;
[0034] 3. Tube mirror;
[0035] 4. Fluorescent mechanism; 401. Rotating slide; 402. Turntable; 403. Fluorescent assembly; 40301. Fixing block; 40302. Heat sink; 40303. Lamp beads; 40304. Collimating lens; 40305. Retaining ring; 40306. Retaining plate; 40307. Filter; 40308. Semi-transparent filter;
[0036] 5. Panoramic camera;
[0037] 6. Lifting lens;
[0038] 7. Complete set of light sources;
[0039] 8. Half-frame cabinet. DETAILED DESCRIPTION
[0040] In order to make the purpose, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only intended to explain the present invention and are not intended to limit the present invention. In addition, the technical features involved in the various embodiments of the present invention described below may be combined with each other as long as they do not conflict with each other.
[0041] Example:
[0042] like Figure 1-6 As shown, the first embodiment of the present invention proposes a high-precision digital slice Z-axis optical path system based on rotational imaging, comprising: a vertical plate 1 and a camera 2, a tube lens 3, a fluorescent mechanism 4, a panoramic camera 5, a lifting lens 6 and a complete set of light sources 7 arranged in sequence on the same side of the vertical axis of the vertical plate 1 to form a Z-axis optical path;
[0043] Among them, the cylindrical mirror 3 is arranged on the upper side wall of the vertical plate 1, and the upper end of the cylindrical mirror 3 is connected to the camera 2; the fluorescent mechanism 4 is arranged on the middle side wall of the vertical plate 1, and the fluorescent mechanism 4 is opposite to the lower end of the cylindrical mirror 3, and the panoramic camera 5 is arranged on the side of the fluorescent mechanism 4; the lifting lens 6 and the complete set of light sources 7 are arranged on the lower side wall of the vertical plate 1 in sequence; the fluorescent mechanism 4 includes a rotatable turntable 402, and a plurality of fluorescent components 403 are provided on the turntable 402, and a light hole penetrating the turntable 402 is provided between each fluorescent component 403 on the turntable 402 for light transmission, and the rotation path of the turntable 402 passes through the lower end of the cylindrical mirror 3 in sequence.
[0044] Specifically, the high-precision digital slice Z-axis optical path system based on rotational imaging of the embodiment of the present invention forms a Z-axis optical path for imaging by sequentially arranging the camera 2, the tube lens 3, the fluorescent mechanism 4, the panoramic camera 5, the lifting lens 6, and the complete set of light sources 7 on the same side of the vertical axis of the vertical plate 1. Using the above-mentioned various structures, three different imaging modes can be achieved, namely, panoramic imaging can be achieved using the panoramic camera 5; dual-channel fluorescence imaging or monochrome fluorescence imaging can be achieved using the camera 2, the tube lens 3, and the fluorescent mechanism 4; and white light bright field imaging can be achieved by moving the fluorescent mechanism 4 out of the optical path and illuminating with white light from the complete set of light sources 7. At the same time, by arranging the camera 2, the tube lens 3, the fluorescent mechanism 4, the panoramic camera 5, the lifting lens 6, and the complete set of light sources 7 on the same axis, the structural layout is reasonable, so that the coordination of the various components is better, thereby ensuring higher final imaging accuracy and higher imaging efficiency.
[0045] In some preferred embodiments, the fluorescent mechanism 4 further includes a rotating slide 401, one end of which is rotatably mounted on the vertical plate 1, and a turntable 402 is rotatably mounted on the upper surface of the rotating slide 401. This design allows the fluorescent mechanism 4 to be moved out of the Z-axis optical path by rotating the rotating slide 401 to articulate relative to the vertical plate 1, thereby also moving the turntable 402 on the rotating slide 401 out of the optical path.
[0046] In some preferred embodiments, the turntable 402 is disc-shaped, and a plurality of mounting areas are evenly arranged at equal angles around the center of the disc-shaped turntable 402, each of which is provided with a fluorescent component 403. Each mounting area can be provided with a fluorescent component 403 of a different color. When multiple fluorescent colors are required, the fluorescent component 403 corresponding to the mounting area can be rotated to a target position, which is located in the light path.
[0047] In some preferred embodiments, the fluorescent component 403 includes: a fixed block 40301, the fixed block 40301 has a first space and a second space, the outlet of the first space is connected to the inlet of the second space; the first space is horizontally provided with a pair of lamp beads 40303, a pair of collimating lenses 40304 and a retaining ring 40305 arranged between the pair of collimating lenses 40304; the second space is provided with a pair of filters 40307 and a semi-transparent filter 40308 arranged between the pair of filters 40307, the pair of filters 40307 are correspondingly located at the inlet and outlet of the second space, and the outlet of the second space is opposite to the lower end of the tube lens 3.
[0048] In the above embodiment, the lamp bead 40303 is used to emit light of a preset color, which is emitted into the second space through a pair of collimating lenses 40304, and then refracted to the exit of the second space through a pair of filters 40307 and a semi-transparent filter 40308 in the second space, and then directly enters the interior of the tube lens 3 through the lower end of the tube lens 3, wherein the retaining ring 40305 provided between the pair of collimating lenses 40304 is used to limit and fix the two.
[0049] In some preferred embodiments, the fluorescent assembly 403 further includes a heat sink 40302 disposed in the first space, and the heat sink 40302 is attached to the lamp bead 40303. The heat sink 40302 is used to dissipate heat from the lamp bead 40303, and the portion of the heat sink 40302 away from the lamp bead 40303 is located outside the first space.
[0050] In some preferred embodiments, the fluorescent component 403 further includes a baffle 40306, which is disposed between the first space and the second space to limit and fix components in the first space to prevent them from entering the second space. The baffle 40306 is made of a transparent material.
[0051] In some preferred embodiments, the system further includes a semi-frame box 8 structure; the semi-frame box 8 structure is disposed on the upright board 1 and is located between the cylindrical mirror 3 and the lifting lens 6; the semi-frame box 8 structure has a storage space and a pair of adjacent openings connected to the storage space, one of which is located on the side connected to the upright board 1, and the other is used to accommodate a portion of the structure of the fluorescent mechanism 4. A pair of symmetrical through holes are also provided on a pair of opposing side surfaces of the semi-frame box 8 structure, and the pair of through holes are located between the cylindrical mirror 3 and the lifting lens 6. The storage space of the semi-frame box 8 is used to accommodate the fluorescent assembly 403 that is rotated between the pair of symmetrical through holes and prevent light from the fluorescent assembly 403 from diffusing.
[0052] In some preferred embodiments, the outer wall of the half-frame box 8 is provided with an L-shaped connecting plate, one side plate of the L-shaped connecting plate is connected to the outer wall of the half-frame box 8, and the side plate can be attached to the outer wall of the half-frame box 8 by bolts, and the other side plate is in a suspended state for connecting the panoramic camera 5.
[0053] In some preferred embodiments, the system further includes a light source, which is disposed on the other side plate of the L-shaped connecting plate and arranged parallel to the panoramic camera 5 to provide light for the panoramic camera 5 when shooting.
[0054] In some preferred embodiments, the lifting lens 6 comprises a single lens or multiple lenses. In the case of a single lens, the lens is positioned in the Z-axis optical path, enabling it to be raised and lowered for focusing and imaging slices of varying thicknesses. In the case of multiple objective lenses, they are mounted in a circular arrangement on a disk. When a specific objective lens is required, the disk rotates to bring the objective lens into the optical path. This multi-objective lens design allows for the selection of different objective lenses for different slice types, resulting in better imaging results.
[0055] It is easy for those skilled in the art to understand that the above are only preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent replacements and improvements made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.
Claims
1. A high-precision digital slice Z-axis optical path system based on rotational imaging, characterized in that: include: A vertical plate (1), wherein a camera (2), a tube lens (3), a fluorescent mechanism (4), a panoramic camera (5), a lifting lens (6) and a complete set of light sources (7) are sequentially arranged on the same side of the vertical axis of the vertical plate (1) to form a Z-axis optical path; The tube mirror (3) is arranged on the upper side wall of the vertical plate (1), and the upper end of the tube mirror (3) is connected to the camera (2); the fluorescent mechanism (4) is arranged on the middle side wall of the vertical plate (1), and the fluorescent mechanism (4) is directly opposite to the lower end of the tube mirror (3); the panoramic camera (5) is arranged on the side of the fluorescent mechanism (4); the lifting lens (6) and the complete set of light sources (7) are sequentially arranged on the lower side wall of the vertical plate (1); The fluorescent mechanism (4) comprises a rotatable turntable (402), a plurality of fluorescent components (403) are provided on the turntable (402), and the rotation path of the turntable (402) passes through the lower end of the tube mirror (3) in sequence.
2. The high-precision digital slice Z-axis optical path system based on rotational imaging according to claim 1, characterized in that: The fluorescent mechanism (4) further comprises a rotating slide (401), one end of which is rotatably mounted on the vertical plate (1), and the turntable (402) is rotatably mounted on the upper surface of the rotating slide (401).
3. The high-precision digital slice Z-axis optical path system based on rotational imaging according to claim 2, characterized in that: The turntable (402) is disc-shaped, and based on the center of the disc-shaped turntable (402), a plurality of installation areas with equal angles are evenly arranged, and each installation area is provided with a fluorescent component (403).
4. The high-precision digital slice Z-axis optical path system based on rotational imaging according to claim 3 is characterized in that: The fluorescent component (403) comprises: A fixed block (40301), the fixed block (40301) having a first space and a second space, wherein the outlet of the first space is connected to the inlet of the second space; The first space is horizontally provided with a lamp bead (40303), a pair of collimating lenses (40304), and a retaining ring (40305) provided between the pair of collimating lenses (40304) in sequence; The second space is provided with a pair of filters (40307) and a semi-transparent filter (40308) arranged between the pair of filters (40307), the pair of filters (40307) are correspondingly located at the entrance and exit of the second space, and the exit of the second space is directly opposite to the lower end of the tube mirror (3).
5. The high-precision digital slice Z-axis optical path system based on rotational imaging according to claim 4, characterized in that: The fluorescent component (403) further includes a heat sink (40302) disposed in the first space, and the heat sink (40302) is attached to the lamp bead (40303).
6. The high-precision digital slice Z-axis optical path system based on rotational imaging according to claim 5, characterized in that: The fluorescent component (403) further includes a baffle (40306), wherein the baffle (40306) is arranged between the first space and the second space, and the baffle (40306) is made of a transparent material.
7. The high-precision digital slice Z-axis optical path system based on rotational imaging according to claim 1, characterized in that: The system further comprises a semi-frame box (8) structure; the semi-frame box (8) structure is provided on the vertical plate (1) and is located between the cylindrical mirror (3) and the lifting lens (6); The semi-frame box (8) structure has a storage space and a pair of openings that are adjacently distributed and connected to the storage space, wherein one opening is located on the connection side with the vertical plate (1), and the other opening is used to accommodate a part of the structure of the fluorescent mechanism (4). A pair of symmetrical through holes are also provided on a pair of opposite side surfaces of the semi-frame box (8), and a pair of the through holes are located between the tube mirror (3) and the lifting lens (6).
8. The high-precision digital slice Z-axis optical path system based on rotational imaging according to claim 7, characterized in that: The outer side wall of the semi-frame box (8) is provided with an L-shaped connecting plate, one side plate of the L-shaped connecting plate is connected to the outer side wall of the semi-frame box (8), and the other side plate is used to connect the panoramic camera (5).
9. The high-precision digital slice Z-axis optical path system based on rotational imaging according to claim 8, characterized in that: The system further comprises a light source, which is arranged on another side plate of the L-shaped connecting plate and is arranged in parallel with the panoramic camera (5).
10. The high-precision digital slice Z-axis optical path system based on rotational imaging according to claim 1, characterized in that: The lifting lens (6) includes a single lens or multiple lenses.
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