Purifying device for medicine for treating respiratory system diseases

By setting the heat exchange tube and filter plug disk in the tank, the problems of oxidation and contamination of acetylcysteine during the production process are solved, and efficient purification and drying process is achieved, and yield is improved.

CN223208986UActive Publication Date: 2025-08-12NANJING WANGZHIXING PHARM TECH CO LTD
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Patent Information

Application Number
CN202422455783.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-10-11
Publication Date
2025-08-12
Estimated Expiration
2034-10-11

AI Technical Summary

Technical Problem

In the prior art, acetylcysteine is easily oxidized during the production process and is easily contaminated by exogenous substances, resulting in a decrease in yield.

Method used

A heat exchange tube and a vertically sliding filter plug disk are installed in the tank body with a double-layer structure. Combined with an electric heating element and a vacuum air pump, the materials are heated, cooled, filtered and dried in the tank body, and avoid oxidation and exogenous contamination.

Benefits of technology

The purification and drying process of acetylcysteine is achieved in the tank, reducing the risk of oxidation and exogenous contamination and improving the yield.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides a purification device for medicines for treating respiratory system diseases, which comprises a tank body, the tank body is of a double-layer structure, a heat exchange tube is arranged in an interlayer, the upper end of the tank body is in threaded connection with an upper cover, and a filter plug disc sliding in the vertical direction is arranged in the tank body. A plurality of filter screens are fixedly connected to the filter plug disc, and an electric heating element is arranged on the filter plug disc. According to the present invention, the purification and the dehydration drying of the material are performed in the tank body, such that the oxidation problem can be avoided, the purification and the dehydration drying are only completed in the tank body, and the exogenous pollution degree of the target product is low.
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Description

Technical Field

[0001] The present invention relates to the technical field of purification, in particular to a purification device for drugs for treating respiratory diseases. Background Art

[0002] During drug production, the target product is typically isolated and purified in the post-reaction system. For example, acetylcysteine, a drug for treating respiratory diseases, is primarily used as a mucolytic agent. It has a strong mucolytic effect. The sulfhydryl groups in its molecules can break disulfide bonds within the glycoprotein polypeptide chains in sputum, thereby reducing sputum viscosity and making it easier to expectorate.

[0003] Acetylcysteine, a strong antioxidant, is itself susceptible to oxidation. The patent titled "A Method for Synthesizing N-Acetyl-L-Cysteine," application number CN202110712377.X, describes a production process involving multiple heating, cooling, and filtration operations. Because acetylcysteine is easily oxidized, the aforementioned production steps inevitably result in reduced yields. Furthermore, multiple transfers and filtrations also make it susceptible to contamination from exogenous substances. Summary of the Invention

[0004] To address the aforementioned issues, the present invention discloses a purification device for treating respiratory diseases. The device comprises a double-layered tank body with heat exchange tubes disposed within the interlayer. A top cover is threadedly connected to the upper end of the tank body. The double-layered structure improves the tank body's thermal insulation, while the heat exchange tubes are used to heat or cool the material within the tank body, primarily for cooling the material.

[0005] The tank body is equipped with a vertically sliding filter disc, fixedly connected to a plurality of filter screens and equipped with an electric heating element. The up-and-down movement of the filter disc traps precipitated solids, while the electric heating element heats the material inside the tank body and dries the precipitated solids. This process allows the material to be purified and dried entirely within the tank body, avoiding oxidation and other issues caused by exposure to air.

[0006] Preferably, a bracket is provided below the tank body, wherein the bracket is a square frame composed of a plurality of rods. The bracket is used to support the tank body, and the rods are all square tubes.

[0007] Preferably, a vacuum air pump is fixedly connected to the bracket, the input end of the vacuum air pump is fixedly connected to a negative pressure tube, and the other end of the negative pressure tube is fixedly connected to the upper portion of the tank. During the drying process, the vacuum air pump and the negative pressure tube are used to extract evaporated gas and reduce the pressure inside the tank, thereby promoting the drying of the air material.

[0008] Preferably, an electric cylinder is fixedly connected to the bottom of the tank, an output end of the electric cylinder is fixedly connected to a telescopic rod, and the other end of the telescopic rod is fixedly connected to the middle of the filter plug disc. When the electric cylinder is activated, the telescopic rod is extended and retracted, thereby achieving the raising or lowering of the filter plug disc.

[0009] Preferably, a sealing ring is fixedly connected to the side wall of the filter plug disc, and the sealing ring contacts the inner wall of the tank body. The sealing ring is provided to ensure that the liquid can only pass through the filter screen, that is, to ensure that all precipitated solids are intercepted, thereby ensuring the yield.

[0010] Preferably, a refrigerant outlet pipe is fixedly connected to the lower side wall of the tank body, and the refrigerant outlet pipe is fixedly connected to the lower end of the heat exchange tube. A refrigerant inlet pipe is fixedly connected to the upper side wall of the tank body, and the refrigerant outlet pipe is fixedly connected to the upper end of the heat exchange tube. That is, the refrigerant is fed into the refrigerant inlet pipe, and as the refrigerant passes through the heat exchange tube, the material in the tank body is cooled, and finally the refrigerant is discharged from the refrigerant outlet pipe.

[0011] Preferably, a material pipe is fixedly connected to the lower side wall of the tank body for feeding liquid material into or out of the tank body.

[0012] The beneficial effects of the present invention are as follows:

[0013] After the reacted solution is passed into the tank, the target product is precipitated by heating or cooling. A filter plug filters the target product, and a vacuum air pump is provided to dry the separated target product. This means that the target product is separated, purified, and dried only within the tank, significantly reducing the degree of oxidation and external contamination. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 It is a three-dimensional schematic diagram of the present invention;

[0015] Figure 2 It is a cross-sectional schematic diagram of the tank body of the present invention;

[0016] Figure 3 It is a three-dimensional schematic diagram of the filter plug disc of the present invention.

[0017] List of reference numerals:

[0018] 1. Bracket; 2. Material pipe; 3. Electric cylinder; 4. Vacuum air pump; 5. Negative pressure pipe; 6. Tank body; 7. Refrigerant outlet pipe; 8. Refrigerant inlet pipe; 9. Upper cover; 10. Heat exchange tube; 11. Telescopic rod; 12. Sealing ring; 13. Filter screen; 14. Filter plug tray. DETAILED DESCRIPTION

[0019] The present invention will be further described below with reference to the accompanying drawings and specific embodiments. It should be understood that the following specific embodiments are intended only to illustrate the present invention and are not intended to limit the scope of the present invention. It should be noted that the terms "front," "rear," "left," "right," "up," and "down" used in the following description refer to directions in the accompanying drawings, and the terms "inward" and "outward" refer to directions toward or away from the geometric center of a particular component, respectively.

[0020] like Figures 1 to 3 As shown, a purification device for treating drugs for respiratory diseases includes a tank body 6. The tank body 6 is a cylindrical structure with a double-layer structure. The double-layer structure can improve the thermal insulation effect of the tank body 6, and a heat exchange tube 10 is provided in the interlayer. The heat exchange tube 10 is used to cool or heat the material inside the tank body 6. However, the heat exchange tube 10 mainly passes a refrigerant for cooling the material inside the tank body 6. The upper end of the tank body 6 is threadedly connected to an upper cover 9. The upper cover 9 is rotated to open and the material in the tank body 6 can be taken out.

[0021] A vertically sliding filter plug disc 14 is provided inside the tank body 6, that is, when the filter plug disc 14 rises or falls, the precipitated fixed material is intercepted and processed. A number of filter screens 13 are fixedly connected to the filter plug disc 14, and the filter screens 13 realize solid-liquid separation. At the same time, a higher strength filter screen 13 needs to be used, and the filter screens 13 can also be laid in multiple layers. An electric heating element is provided on the filter plug disc 14, and the electric heating element generates heat when energized, that is, the liquid material is heated or the precipitated solid is cooled.

[0022] A bracket 1 is provided below the tank body 6. The bracket 1 is a square frame composed of a plurality of rods. The rods are square tubes with square cross-sections.

[0023] A vacuum air pump 4 is fixedly connected to the bracket 1, and a negative pressure pipe 5 is fixedly connected to the input end of the vacuum air pump 4. The other end of the negative pressure pipe 5 is fixedly connected to the upper part of the tank body 6. That is, when the solid material is dried, the vacuum air pump 4 is running, so that the interior of the tank body 6 is reduced, which can promote the drying effect. At the same time, the evaporated gas is sent out of the tank body 6 through the negative pressure pipe 5 and the vacuum air pump 4.

[0024] The bottom of the tank 6 is fixedly connected to an electric cylinder 3. The output end of the electric cylinder 3 is fixedly connected to a telescopic rod 11. The other end of the telescopic rod 11 is fixedly connected to the middle of the filter plug 14. When the electric cylinder 3 is activated, the telescopic rod 11 expands and contracts, causing the filter plug 14 to rise or fall, thus separating the precipitated solid material.

[0025] Furthermore, the filter plug disc 14 and the telescopic rod 11 are connected by means of a threaded connection or a latch, which makes it easy to remove the filter plug disc 14 from the telescopic rod 11 .

[0026] The side wall of the filter plug disc 14 is fixedly connected with a sealing ring 12, which contacts the inner wall of the tank body 6. The sealing ring 12 is provided to improve the sealing between the filter plug disc 14 and the tank body 6, ensuring that the precipitated solids are completely separated.

[0027] A refrigerant outlet pipe 7 is fixedly connected to the lower side wall of the tank body 6, and the refrigerant outlet pipe 7 is fixedly connected to the lower end of the heat exchange tube 10. A refrigerant inlet pipe 8 is fixedly connected to the upper side wall of the tank body 6, and the refrigerant outlet pipe 7 is fixedly connected to the upper end of the heat exchange tube 10. The refrigerant is fed into the heat exchange tube 10 through the refrigerant inlet pipe 8. As the refrigerant passes through the heat exchange tube 10, it cools the material inside the tank body 6 and is finally discharged through the refrigerant outlet pipe 7.

[0028] The lower side wall of the tank body 6 is fixedly connected with a material pipe 2. The material pipe 2 is to send liquid into or out of the interior of the tank body 6.

[0029] Working principle: When the device is in use, the system solution after the reaction is sent out of the interior of the tank body 6 through the material pipe 2, and the filter plug disc 14 is in the upper position at this time;

[0030] Then the solution is heated, that is, the electric heating element on the filter plug disc 14 is energized to generate heat. If necessary, heat medium can be introduced into the heat exchange tube 10 to increase the heating rate.

[0031] Then, the electric cylinder 3 operates, and the filter plug disc 14 descends to the lower position. The undissolved solids in the solution are retained by the filter plug disc 14 and eventually precipitate at the bottom. At this time, refrigerant is introduced into the heat exchange tube 10 to cool the solution, and the target product in the solution precipitates. At this time, the electric cylinder 3 operates again, and the telescopic rod 11 extends, so that the filter plug disc 14 returns to the upper position. In the process, the precipitated target product is trapped in the upper part of the filter plug disc 14.

[0032] Finally, the solution under the filter plug disc 14 and the fixed objects therein are sent out of the tank body 6 through the material pipe 2, and the electric heating element on the filter plug disc 14 is energized again to heat the target product. At the same time, the vacuum air pump 4 works to vacuum the tank body 6. After the target product is dried, the upper cover 9 is opened and it can be taken out.

[0033] In the above process, the material is purified and dehydrated and dried inside the tank 6, which not only avoids the oxidation problem, but also completes the purification and dehydration steps only in the tank 6, and the target product is less contaminated by external sources.

[0034] The technical means disclosed in the solution of the present invention are not limited to the technical means disclosed in the above-mentioned embodiment, but also include technical solutions composed of any combination of the above technical features.

Claims

1. A purification device for drugs for treating respiratory diseases, characterized by: The tank body (6) comprises a double-layer structure, wherein a heat exchange tube (10) is provided in the interlayer, and an upper cover (9) is threadedly connected to the upper end of the tank body (6); A filter plug disc (14) that slides vertically is provided inside the tank body (6), a plurality of filter screens (13) are fixedly connected to the filter plug disc (14), and an electric heating element is provided on the filter plug disc (14).

2. The purification device for treating respiratory diseases according to claim 1, characterized in that: A bracket (1) is provided below the tank body (6), and the bracket (1) is a square frame composed of a plurality of rods.

3. The purification device for treating respiratory diseases according to claim 2, characterized in that: The bracket (1) is fixedly connected to a vacuum air pump (4), an input end of the vacuum air pump (4) is fixedly connected to a negative pressure pipe (5), and the other end of the negative pressure pipe (5) is fixedly connected to the upper part of the tank body (6).

4. The purification device for treating respiratory diseases according to claim 1, characterized in that: The bottom of the tank body (6) is fixedly connected to an electric cylinder (3), the output end of the electric cylinder (3) is fixedly connected to a telescopic rod (11), and the other end of the telescopic rod (11) is fixedly connected to the middle of the filter plug disc (14).

5. The purification device for treating respiratory diseases according to claim 1, characterized in that: A sealing ring (12) is fixedly connected to the side wall of the filter plug disc (14), and the sealing ring (12) is in contact with the inner wall of the tank body (6).

6. The purification device for treating respiratory diseases according to claim 1, characterized in that: The lower side wall of the tank body (6) is fixedly connected to a refrigerant outlet pipe (7), and the refrigerant outlet pipe (7) is fixedly connected to the lower pipe opening of the heat exchange pipe (10). The upper side wall of the tank body (6) is fixedly connected to a refrigerant inlet pipe (8), and the refrigerant outlet pipe (7) is fixedly connected to the upper pipe opening of the heat exchange pipe (10).

7. The purification device for treating respiratory diseases according to claim 1, characterized in that: The lower side wall of the tank body (6) is fixedly connected to a material pipe (2).

Citation Information

Patent Citations

  • A method for synthesizing N-acetyl-L-cysteine

    CN113461580B