Dissolving device for pharmaceutical analysis

Abstract

The utility model relates to a dissolving device for pharmaceutical analysis, which belongs to the technical field of pharmaceutical analysis equipment and comprises a dissolving barrel and a control instrument, the dissolving barrel is mounted on the control instrument, a sealing cover is movably mounted at the top of the dissolving barrel, and a mounting plate is movably mounted above the inside of the dissolving barrel. A temperature control device is fixedly installed outside the test tube, a filter tube is movably installed inside the test tube, a filter screen is movably installed below the filter tube, the medicine feeding tube is communicated with the interior of the dissolving barrel, a rotating mechanism is arranged inside the dissolving barrel, and the rotating mechanism comprises a rotating gear, a movable gear ring, the test tube, a transmission shaft and a motor which are of a circular structure; the rotating gear is fixedly mounted in the dissolving barrel and located at the top of the mounting plate, the movable gear ring is fixedly connected to the side wall of the test tube in a sleeving manner, and the motor is fixedly mounted in the dissolving barrel; according to the medicine dissolving device, the medicine dissolving efficiency is improved, meanwhile, the filter screen is not prone to being blocked, and the purity of a solution is guaranteed.

Description

Technical Field

[0001] The utility model relates to the technical field of drug analysis equipment, in particular to a dissolving device for drug analysis. Background Art

[0002] Pharmaceutical analysis equipment is a precision device designed to dissolve drug samples accurately and evenly during drug analysis or quality control to ensure the accuracy and reliability of subsequent analysis. Its main function is to dissolve solid drugs or semi-solid drug preparations in liquid solvents to form a uniform solution for subsequent analysis and testing.

[0003] After searching the Chinese patent with publication number CN218307273U, a drug dissolution device for drug analysis is disclosed, comprising: a tank body, a liquid outlet pipe, and a liquid inlet pipe; the tank body is a cylindrical shell structure, and the liquid outlet pipe is arranged on one side of the tank body, and one end of the liquid outlet pipe is fixedly connected to the middle position of the bottom surface of the tank body; the water pump is fixedly installed on one side of the top surface of the tank body, and one end of the water pump is connected to the liquid outlet pipe, and the other end of the water pump is connected to the liquid inlet pipe; the stirring motor is fixedly installed in the middle position of the top surface of the tank body, and the lower end of the stirring motor is fixedly connected to the stirring rod; the drug holding net is plugged into the inside of the placement hole, and the crushing motor is fixedly installed above the drug holding net through the engagement of the crushing motor fixing plate and the claw; this utility model has the advantages of simple structure, fast drug dissolution speed, and uniform concentration of the dissolved liquid after the drug is dissolved, through the improvement of the drug dissolution device for drug analysis, thereby effectively solving the problems and shortcomings of the existing device.

[0004] Based on the above search and combined with the existing technology, we found that:

[0005] In the process of dissolving large-particle drugs in current technology, large-particle drugs may cause clogging of the filter. At the same time, when the drug and the solution are mixed, the dissolution efficiency of large-particle drugs is poor, which affects practicality. Utility Model Content

[0006] In order to solve the above technical problems, the utility model proposes a dissolution device for drug analysis, which can improve the dissolution efficiency of the drug, while preventing the filter from being easily clogged and ensuring the purity of the solution.

[0007] The technical solution for achieving the purpose of the utility model is: a dissolution device for drug analysis, comprising a dissolution cylinder and a controller, the dissolution cylinder being mounted on the controller, a sealing cover being movably mounted on the top of the dissolution cylinder, a mounting plate being movably mounted on the upper interior of the dissolution cylinder, a plurality of test tubes being arranged on the mounting plate, a temperature control device being fixedly mounted on the exterior of the test tubes, a V-shaped funnel being fixedly mounted on the bottom of the test tubes, a filter tube being movably mounted on the interior of the test tubes, a filter screen being movably mounted below the filter tubes, a drug discharge tube being embedded in the bottom of the dissolution cylinder, the drug discharge tube being connected to the interior of the dissolution cylinder, and a rotating mechanism being arranged inside the dissolution cylinder;

[0008] The rotating mechanism includes a rotating gear, a movable gear ring, a test tube, a transmission shaft and a motor in a circular structure. The rotating gear is fixedly installed inside the dissolution cylinder, the rotating gear is located on the top of the mounting plate, the movable gear ring is fixedly sleeved on the side wall of the test tube, the motor is fixedly installed inside the dissolution cylinder, the transmission shaft is fixedly installed on the output end of the motor, and the top of the transmission shaft is fixedly connected to the mounting plate.

[0009] In some embodiments, a support rod is fixedly installed inside the medicine tube, the support rod is connected to the motor, the motor is fixedly installed inside the dissolution cylinder through the support rod, a shaft sleeve is provided on the outside of the transmission shaft, a connecting rod is fixedly installed on the top of the rotating gear, the connecting rod is fixedly connected to the sealing cover, and the rotating gear is fixedly installed inside the dissolution cylinder through the connecting rod.

[0010] In some embodiments, a plurality of connecting springs are installed between the filter tube and the filter screen, and the filter screen is movably installed at the bottom of the filter tube through the connecting springs.

[0011] In some embodiments, a filter tube cover is movably installed on the top of the filter tube, and the filter tube cover is used to seal the interior of the filter tube. A limit seat is fixedly installed inside the test tube, and the limit seat is an annular structure. A fixed seat is fixedly installed on the side wall of the filter tube at a position corresponding to the limit seat. The fixed seat and the limit seat fit together, and the filter tube is movably installed inside the test tube through the limit seat and the fixed seat.

[0012] In some embodiments, a sealing plate is provided at the bottom of the test tube, and the sealing plate seals the bottom of the test tube when the mounting plate and the test tube rotate.

[0013] In some embodiments, a water inlet pipe is fixedly mounted on the side wall of the dissolution cylinder. The water inlet pipe is a tubular structure and is connected to an external water supply device. A water outlet pipe is mounted on the side wall of the controller.

[0014] Compared with the prior art, the present invention has the following significant advantages:

[0015] The utility model is provided with a rotating mechanism. Before conducting a test, the sealing cover is first opened, and then the medicine and solution are placed in the interior of the filter tube. Subsequently, the motor is started. The motor drives the mounting plate to rotate through the transmission shaft, and then drives multiple test tubes to revolve. At the same time, a rotating gear is fixed inside the dissolution cylinder, and a movable gear ring engaged with the rotating gear is sleeved on the test tube. When the test tube revolves, the movable gear ring will mesh and move on the rotating gear, and then drive the test tube to rotate. Therefore, the test tube can rotate while revolving, thereby improving the dissolution efficiency of the medicine, and at the same time, the filter screen is not easy to be clogged, and the purity of the solution is guaranteed. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] The present invention will be further explained below with reference to the accompanying drawings and embodiments:

[0017] Figure 1 This is a schematic diagram of the main structure provided in one embodiment of the present invention;

[0018] Figure 2 This is a cross-sectional view of the main structure provided in one embodiment of the present invention;

[0019] Figure 3 The utility model provides in one embodiment Figure 2 Enlarged view of point A in the middle;

[0020] Figure 4 The utility model provides in one embodiment Figure 2 Enlarged view of point B in the middle.

[0021] Description of reference numerals:

[0022] 1. Dissolution cylinder; 2. Sealing cover; 3. Connecting rod; 4. Rotating gear; 5. Mounting plate; 6. Movable gear ring; 7. Test tube; 8. Temperature control device; 9. Sealing plate; 10. V-shaped funnel; 11. Drive shaft; 12. Bushing; 13. Motor; 14. Support rod; 15. Drug discharge tube; 16. Filter tube; 17. Filter tube cover; 18. Connecting spring; 19. Filter screen; 20. Limit seat; 21. Fixed seat; 22. Water inlet pipe; 23. Water outlet pipe; 24. Controller. DETAILED DESCRIPTION

[0023] The following is a detailed description of the present invention, clearly and completely describing the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only a part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0024] The present invention provides a dissolution device for drug analysis through improvement. The technical solution of the present invention is:

[0025] like Figure 1 Figure 2 As shown, a dissolution device for drug analysis includes a dissolution cylinder 1 and a controller 24. The dissolution cylinder 1 is a cylindrical hollow structure. The dissolution cylinder 1 is installed on the controller 24. A sealing cover 2 is movably installed on the top of the dissolution cylinder 1. The sealing cover 2 is disc-shaped. A mounting plate 5 is movably installed on the upper part of the interior of the dissolution cylinder 1. The mounting plate 5 is a circular plate. A plurality of test tubes 7 are arranged on the mounting plate 5. The test tubes 7 are hollow structures. A temperature control device 8 is fixedly installed on the outside of the test tubes 7. The temperature control device 8 is a circular ring structure. A V-shaped funnel 10 is fixedly installed on the bottom of the test tube 7. The V-shaped funnel 10 is a hollow frustum. The interior of the V-shaped funnel 10 gradually becomes smaller from top to bottom. A filter tube 16 is movably installed inside the test tube 7. A filter screen 19 is movably installed below the filter tube 16. A drug lowering tube 15 is inlaid on the bottom of the dissolution cylinder 1. The drug lowering tube 15 is connected to the interior of the dissolution cylinder 1. The interior of the dissolution cylinder 1 is provided with a rotating mechanism.

[0026] The rotating mechanism includes a rotating gear 4, a movable gear ring 6, a test tube 7, a transmission shaft 11 and a motor 13. The rotating gear 4 is a circular structure. The rotating gear 4 is fixedly mounted inside the dissolution cylinder 1. The rotating gear 4 is located on the top of the mounting plate 5. The movable gear ring 6 is an annular structure. The movable gear ring 6 is fixedly sleeved on the side wall of the test tube 7, and the movable gear ring 6 and the rotating gear 4 are meshed for transmission. The motor 13 is fixedly mounted inside the dissolution cylinder 1. The transmission shaft 11 is a cylindrical structure. The transmission shaft 11 is fixedly mounted on the output end of the motor 13. The top of the transmission shaft 11 is connected to the mounting plate 5. The plate 5 is fixedly connected. First, the sealing cover 2 is opened, and then the medicine and solution are placed inside the filter tube 16. Then the motor 13 is started. The motor 13 drives the mounting plate 5 to rotate through the transmission shaft 11, and then drives multiple test tubes 7 to revolve. At the same time, a rotating gear 4 is fixed inside the dissolution cylinder 1, and a movable gear ring 6 engaged with the rotating gear 4 is sleeved on the test tube 7. When the test tube 7 revolves, the movable gear ring 6 will engage and move on the rotating gear 4, and then drive the test tube 7 to rotate, so that the test tube 7 can rotate while revolving, thereby improving the dissolution efficiency.

[0027] like Figure 2 As shown, a support rod 14 is fixedly installed inside the medicine tube 15, and the support rod 14 is connected to the motor 13. The motor 13 is fixedly installed inside the dissolution cylinder 1 through the support rod 14. A shaft sleeve 12 is provided on the outside of the transmission shaft 11. A connecting rod 3 is fixedly installed on the top of the rotating gear 4. The connecting rod 3 is fixedly connected to the sealing cover 2, and the rotating gear 4 is fixedly installed inside the dissolution cylinder 1 through the connecting rod 3.

[0028] like Figure 2 and Figure 3 As shown, a plurality of connecting springs 18 are installed between the filter tube 16 and the filter screen 19, and the filter screen 19 is movably installed at the bottom of the filter tube 16 through the connecting springs 18; by providing the connecting springs 18, when the test tube 7 revolves, the centrifugal force generated will drive the filter screen 19 to rotate inside the test tube 7, thereby further improving the drug dissolution rate.

[0029] A filter tube cover 17 is movably installed on the top of the filter tube 16. The filter tube cover 17 is used to seal the inside of the filter tube 16. A limit seat 20 is fixedly installed inside the test tube 7. The limit seat 20 is an annular structure. A fixing seat 21 is fixedly installed on the side wall of the filter tube 16 at a position corresponding to the limit seat 20. The fixing seat 21 and the limit seat 20 fit together. The filter tube 16 is movably installed inside the test tube 7 through the limit seat 20 and the fixing seat 21.

[0030] like Figure 2 Figure 4 As shown, a sealing plate 9 is provided at the bottom of the test tube 7, and the sealing plate 9 seals the bottom of the test tube 7 when the mounting plate 5 and the test tube 7 rotate to prevent the solution from leaking. After the solution is completely dissolved, the dissolved liquid flows through the sealing plate 9 to the V-shaped funnel 10 and the medicine tube 15.

[0031] A water inlet pipe 22 is fixedly installed on the side wall of the dissolution cylinder 1. The water inlet pipe 22 is a tubular structure and is connected to an external water supply device. A water outlet pipe 23 is installed on the side wall of the controller 24; the water outlet pipe 23 is used to discharge the tested medicine. Clean water can be injected into the interior of the dissolution cylinder 1 through the water inlet pipe 22 to clean the residual medicine to avoid mutual contamination of the medicine and affect the test results.

[0032] The specific working methods are:

[0033] By providing a rotating mechanism, before conducting the test, first open the sealing cover 2, then put the medicine and solution into the inside of the filter tube 16, and then start the motor 13. The motor 13 drives the mounting plate 5 to rotate through the transmission shaft 11, and then drives multiple test tubes 7 to revolve. At the same time, a rotating gear 4 is fixed to the inside of the dissolution cylinder 1, and a movable gear ring 6 engaged with the rotating gear 4 is sleeved on the test tube 7. When the test tube 7 revolves, the movable gear ring 6 will engage and move on the rotating gear 4, and then drive the test tube 7 to rotate, so that the test tube 7 can rotate while revolving, thereby improving the dissolution efficiency of the medicine. At the same time, the filter screen 19 is not easy to be blocked, and the purity of the solution is guaranteed.

[0034] The technical means disclosed in the present invention are not limited to the technical means disclosed in the above technical means, but also include technical solutions composed of equivalent replacements of the above technical features. Matters not covered in the present invention belong to the common knowledge of those skilled in the art.

Claims

1. A dissolution device for drug analysis, comprising a dissolution cylinder (1) and a controller (24), wherein the dissolution cylinder (1) is mounted on the controller (24), and a sealing cover (2) is movably mounted on the top of the dissolution cylinder (1), characterized in that: A mounting plate (5) is movably mounted on the upper portion of the dissolving cylinder (1), a plurality of test tubes (7) are arranged on the mounting plate (5), a temperature control device (8) is fixedly mounted on the outside of the test tube (7), a V-shaped funnel (10) is fixedly mounted on the bottom of the test tube (7), a filter tube (16) is movably mounted on the inside of the test tube (7), a filter screen (19) is movably mounted below the filter tube (16), a lower medicine tube (15) is embedded and mounted on the bottom of the dissolving cylinder (1), the lower medicine tube (15) is communicated with the inside of the dissolving cylinder (1), and a rotating mechanism is arranged inside the dissolving cylinder (1); The rotating mechanism comprises a rotating gear (4), a movable gear ring (6), a test tube (7), a transmission shaft (11) and a motor (13). The rotating gear (4) is fixedly mounted inside the dissolving cylinder (1), the rotating gear (4) is located on the top of the mounting plate (5), the movable gear ring (6) is fixedly sleeved on the side wall of the test tube (7), the motor (13) is fixedly mounted inside the dissolving cylinder (1), the transmission shaft (11) is fixedly mounted on the output end of the motor (13), and the top of the transmission shaft (11) is fixedly connected to the mounting plate (5).

2. A dissolution device for drug analysis according to claim 1, characterized in that: A support rod (14) is fixedly installed inside the medicine tube (15), the support rod (14) is connected to the motor (13), and the motor (13) is fixedly installed inside the dissolving cylinder (1) through the support rod (14). A shaft sleeve (12) is provided outside the transmission shaft (11), and a connecting rod (3) is fixedly installed on the top of the rotating gear (4). The connecting rod (3) is fixedly connected to the sealing cover (2), and the rotating gear (4) is fixedly installed inside the dissolving cylinder (1) through the connecting rod (3).

3. A dissolution device for drug analysis according to claim 1, characterized in that: A plurality of connecting springs (18) are installed between the filter tube (16) and the filter screen (19), and the filter screen (19) is movably installed at the bottom of the filter tube (16) through the connecting springs (18).

4. A dissolution device for drug analysis according to claim 1, characterized in that: A filter tube cover (17) is movably mounted on the top of the filter tube (16). The filter tube cover (17) is used to seal the interior of the filter tube (16). A limiting seat (20) is fixedly mounted inside the test tube (7). The limiting seat (20) is an annular structure. A fixing seat (21) is fixedly mounted on the side wall of the filter tube (16) at a position corresponding to the limiting seat (20). The fixing seat (21) and the limiting seat (20) are fitted together. The filter tube (16) is movably mounted inside the test tube (7) via the limiting seat (20) and the fixing seat (21).

5. A dissolution device for drug analysis according to claim 1, characterized in that: A sealing plate (9) is provided at the bottom of the test tube (7), and the sealing plate (9) seals the bottom of the test tube (7) when the mounting plate (5) and the test tube (7) rotate.

6. A dissolution device for drug analysis according to claim 1, characterized in that: A water inlet pipe (22) is fixedly mounted on the side wall of the dissolving cylinder (1). The water inlet pipe (22) is a tubular structure and is connected to an external water supply device. A water outlet pipe (23) is mounted on the side wall of the controller (24).

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