Pre-numbering sample collection device corresponding to 96-well plate

Abstract

The utility model provides a pre-numbering sample collecting device corresponding to a 96-well plate, which comprises centrifugal tubes and a storage box, the storage box is provided with a plurality of placing holes corresponding to hole sites on the 96-well plate, and the placing holes are used for placing the centrifugal tubes; serial numbers corresponding to hole sites on the 96-well plate are marked on the centrifugal tubes. The 96-well plate storage box is simple in structure, the placing holes corresponding to the hole sites on the 96-well plate are formed in the storage box, and the pre-numbers consistent with the information of the corresponding hole sites on the 96-well plate are marked on the centrifuge tubes in advance, so that multiple batches of centrifuge tubes do not need to be numbered in the whole experiment process, and the experiment efficiency is improved. And the information of the blood collection tube only needs to correspond to the final 96-well plate, so that the pretreatment process of the sample is greatly simplified.

Description

Technical Field

[0001] The utility model relates to the technical field of clinical detection devices, in particular to a pre-numbered sample collection device corresponding to a 96-well plate. Background Art

[0002] In clinical testing, a large number of samples are required for testing every day, usually 200-300 samples. When these samples arrive at the laboratory, they are stored in blood collection tubes. The blood collection tubes have a unique number for the specimen (usually a QR code, which is scanned and identified and matched in the system as a unique identification number), patient name, ward, and other information.

[0003] According to the following steps, you need to 1) remove the plasma from the upper layer of the blood collection tube and transfer it to a new centrifuge tube (named centrifuge tube 01). At this time, centrifuge tube 01 needs to be numbered or marked in advance according to the original sample for identification and traceability; 2) accurately transfer a certain amount of plasma (for example, 200 microliters) to a new centrifuge tube (named centrifuge tube 02) in preparation for the next step of processing. Because the next operation requires quantitative measurement, this step requires accurate transfer of a certain amount of plasma. Of course, centrifuge tube 02 also needs to be numbered or marked on the tube; 3) Next, add a precipitant or related reagent to centrifuge tube 02. Reagents are used to remove proteins. After the precipitation is produced, it needs to be centrifuged at high speed in a centrifuge. Because it needs to enter the centrifuge, it is very important to number it in advance. If there is no clear number on centrifuge tube 02 at this time, it will become difficult to distinguish in the centrifuge; 4) After centrifugation, the supernatant needs to be transferred to a new centrifuge tube (named centrifuge tube 03). Of course, centrifuge tube 03 also needs to be numbered or marked on the tube; 5) Next, other reagents need to be further added to centrifuge tube 03 for further treatment such as liquid-liquid extraction or solid-phase extraction or derivatization. More new centrifuge tubes will be needed, which will not be described in detail one by one. 6) Finally, the final solution after treatment will be transferred to a 96-well plate and prepared for injection into a liquid chromatography-mass spectrometer for analysis (currently, the 96-well plate is the most common sample carrier for liquid chromatography-mass spectrometry, and approximately 95% of biological sample analyses are performed in 96-well plates);

[0004] In summary, the sample processing process involves a large number of centrifuge tube numbering tasks. If the number of samples to be analyzed is large, these numbering tasks will take up a lot of time. At least 2 hours a day need to be spent on numbering centrifuge tubes. Therefore, how to simplify the numbering process is an urgent problem to be solved in this field. Utility Model Content

[0005] In view of the defects in the prior art, the purpose of the present invention is to provide a pre-numbered sample collection device corresponding to a 96-well plate.

[0006] The pre-numbered sample collection device corresponding to a 96-well plate provided by the present invention comprises a centrifuge tube and a storage box, wherein the storage box is provided with a plurality of placement holes corresponding to the well positions on the 96-well plate, and the placement holes are used to place the centrifuge tube;

[0007] The centrifuge tubes are marked with numbers corresponding to the well positions on the 96-well plate.

[0008] Preferably, the tube cap and / or the tube body of the centrifuge tube are marked with numbers.

[0009] Preferably, the opening size of the placement hole matches the size of the centrifuge tube body and is smaller than the size of the centrifuge tube cap.

[0010] Preferably, the numbers on the centrifuge tubes match the row and column numbers of the corresponding wells in all wells on the 96-well plate.

[0011] Preferably, the centrifuge tube is marked with a number, an alphabetical number or a number combined with letters.

[0012] Preferably, the numerical number matches the column number of the corresponding well position in all well positions on the 96-well plate, and the letter number matches the row number of the corresponding well position in all well positions on the 96-well plate.

[0013] Preferably, the range of the digital numbers on the centrifuge tubes is 1-12, and the range of the letter numbers on the centrifuge tubes is AH.

[0014] Preferably, the placement hole of the storage box is marked with a position number that is the same as the number on the centrifuge tube.

[0015] Preferably, the centrifuge tubes include centrifuge tubes of various specifications.

[0016] Compared with the prior art, the present invention has the following beneficial effects:

[0017] The utility model has a simple structure. By opening placement holes corresponding to the well positions on the 96-well plate in the storage box and marking the centrifuge tubes with pre-numbers that are consistent with the corresponding well position information on the 96-well plate in advance, it is no longer necessary to number multiple batches of centrifuge tubes during the entire experiment. It is only necessary to match the information of the blood collection tubes with the final 96-well plate, which greatly simplifies the sample pretreatment process. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Other features, objects and advantages of the present invention will become more apparent from the detailed description of the non-limiting embodiments with reference to the following drawings:

[0019] Figure 1 This is a schematic diagram of the structure of the utility model from a top view;

[0020] Figure 2 Schematic diagram of the structure of a standard 96-well plate in the prior art.

[0021] The figure shows:

[0022] Centrifuge tube 1 storage box 2 DETAILED DESCRIPTION

[0023] The present invention will be described in detail below with reference to specific embodiments. The following embodiments will help those skilled in the art further understand the present invention, but are not intended to limit the present invention in any way. It should be noted that a person skilled in the art may make various variations and improvements without departing from the scope of the present invention. Such variations and improvements are all within the scope of protection of the present invention.

[0024] The utility model discloses a pre-numbered sample collection device corresponding to a 96-well plate. By designing pre-numbered centrifuge tubes with exactly the same positions and names as the 96-well plate and pre-installing them in a storage box, it is no longer necessary to number multiple batches of centrifuge tubes during the entire experimental process. It is only necessary to match the information of the blood collection tubes with the final 96-well plate, which greatly simplifies the sample pre-treatment process.

[0025] The present invention provides a pre-numbered sample collection device for a 96-well plate, comprising a centrifuge tube 1 and a storage box 2. The storage box 2 is provided with a plurality of placement holes corresponding to the well positions on the 96-well plate, wherein the placement holes are used to place the centrifuge tube 1. The centrifuge tube 1 is marked with numbers corresponding to the well positions on the 96-well plate. Preferably, the cap and / or body of the centrifuge tube 1 are marked with numbers. The opening size of the placement holes matches the size of the body of the centrifuge tube 1 and is smaller than the size of the cap of the centrifuge tube 1.

[0026] like Figure 1 As shown, the number on the centrifuge tube 1 matches the number of rows and columns of the corresponding well position in all well positions on the 96-well plate. The centrifuge tube 1 is marked with a number, an alphabetical number, or a combination of numbers and letters. The number matches the number of columns of the corresponding well position in all well positions on the 96-well plate, and the alphabetical number matches the number of rows of the corresponding well position in all well positions on the 96-well plate.

[0027] Preferably, the placement holes of the storage box 2 are marked with position numbers that are the same as the numbers on the centrifuge tubes 1. The centrifuge tubes 1 include centrifuge tubes 1 of various specifications.

[0028] Example 1

[0029] This embodiment discloses a pre-numbered sample collection device corresponding to a 96-well plate. Pre-numbered centrifuge tubes 1 are designed with the same positions and names as the 96-well plate and are pre-installed in a storage box 2 to solve the problem of requiring a lot of manual work to number the centrifuge tubes during sample pre-processing.

[0030] The pre-numbered sample collection device corresponding to the 96-well plate includes a storage box 2 for storing pre-numbered centrifuge tubes 1. The placement holes on the storage box 2 are consistent with the hole positions on the 96-well plate, that is, a 12×8 position design. Figure 2 Also includes a pre-numbered centrifuge tube 1 (commonly 1.5mL, 2mL, etc.), the centrifuge tube 1 is pre-numbered on the cap or tube body, the numbering rules are as follows Figure 1 As shown, the range of the digital numbers on the centrifuge tube 1 is 1-12, and the range of the letter numbers on the centrifuge tube 1 is AH.

[0031] During use, the pre-numbered centrifuge tubes 1 need to be placed in a consistent position in a storage box 2 and then removed and used in a corresponding 96-well plate. By designing pre-numbered centrifuge tubes that are aligned with the 96-well plate, the problem of numbering centrifuge tubes when measuring a large number of samples is solved. Because the operation usually involves many steps, not just one batch of centrifuge tubes needs to be numbered, but often multiple batches of centrifuge tubes need to be numbered, which greatly reduces work efficiency. The pre-numbered centrifuge tube design allows experimenters to start experiments immediately without the need for numbering, saving approximately 2-3 hours of work time per day.

[0032] In the description of this application, it should be understood that the terms "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc., indicating the orientation or position relationship, are based on the orientation or position relationship shown in the accompanying drawings, and are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on this application.

[0033] The above describes specific embodiments of the present invention. It should be understood that the present invention is not limited to the specific embodiments described above, and those skilled in the art may make various changes or modifications within the scope of the claims, which do not affect the essence of the present invention. The embodiments of this application and the features in the embodiments may be combined with each other in any manner unless there is a conflict.

Claims

1. A pre-numbered sample collection device corresponding to a 96-well plate, characterized in that: It comprises a centrifuge tube (1) and a storage box (2), wherein the storage box (2) is provided with a plurality of placement holes corresponding to the well positions on a 96-well plate, and the placement holes are used to place the centrifuge tube (1); The centrifuge tube (1) is marked with numbers corresponding to the well positions on the 96-well plate; The tube cap and / or the tube body of the centrifuge tube (1) are marked with numbers; The numbers on the centrifuge tubes (1) match the row and column numbers of the corresponding wells in all the wells on the 96-well plate.

2. The pre-numbered sample collection device corresponding to a 96-well plate according to claim 1, characterized in that: The opening size of the placement hole matches the size of the centrifuge tube (1) body and is smaller than the size of the centrifuge tube (1) cover.

3. The pre-numbered sample collection device corresponding to a 96-well plate according to claim 1, characterized in that: The centrifuge tube (1) is marked with a number, an alphabetical number or a number combined with letters.

4. The pre-numbered sample collection device corresponding to a 96-well plate according to claim 3, characterized in that: The numerical numbers match the column numbers of the corresponding well positions in all well positions on the 96-well plate, and the letter numbers match the row numbers of the corresponding well positions in all well positions on the 96-well plate.

5. The pre-numbered sample collection device corresponding to a 96-well plate according to claim 4, characterized in that: The range of the digital numbers on the centrifuge tube (1) is 1-12, and the range of the letter numbers on the centrifuge tube (1) is AH.

6. The pre-numbered sample collection device corresponding to a 96-well plate according to claim 1, characterized in that: The placement hole of the storage box (2) is marked with a position number that is the same as the number on the centrifuge tube (1).

7. The pre-numbered sample collection device corresponding to a 96-well plate according to claim 1, characterized in that: The centrifuge tubes (1) include a plurality of centrifuge tubes (1) of different specifications.

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