Cell culture oscillator

Through the design of automatic clamping mechanism and adjustable oscillation amplitude, the problems of low pick-up and placement efficiency of culture liquid containers and difficulty in adjusting oscillation amplitude in the prior art are solved, and efficient and flexible cell culture operations are achieved.

CN223249180UActive Publication Date: 2025-08-22GANSU AGRI UNIV
View PDF 1 Cites 0 Cited by

Patent Information

Application Number
CN202422428280.8
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-10-09
Publication Date
2025-08-22
Estimated Expiration
2034-10-09

AI Technical Summary

Technical Problem

Existing cell culture oscillators need to be manually operated when picking up and putting the culture liquid container, which affects efficiency and is difficult to adjust the oscillation amplitude according to experimental needs and cell type.

Method used

The automatic clamping mechanism and adjustable oscillation amplitude design are adopted. The clamping is released through the magnetic attraction of the permanent magnet and the electromagnet, combined with the angle adjustment of the threaded adjustment rod and the oscillation wheel, to achieve flexible adjustment of the automatic clamping and oscillation amplitude.

Benefits of technology

It improves the pick-up and placement efficiency of the culture liquid container and the adaptability of the device, and can flexibly adjust the oscillation amplitude according to experimental needs and cell type, making the operation simple and convenient.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN223249180U_ABST
    Figure CN223249180U_ABST
Patent Text Reader

Abstract

The utility model discloses a cell culture oscillator which comprises a box body, two parallel guide rods are fixedly connected between the two sides of the inner wall of the box body, and an oscillation plate is slidably sleeved between the outer surfaces of the two guide rods. When a culture solution container needs to be taken and placed into the storage cavity, power sources of all the electromagnets are closed through the control panel, the ferromagnetism of the electromagnets disappears, the electromagnets are magnetically attracted through the permanent magnets, the electromagnets are fixedly connected with the device box, the permanent magnets move towards the sides close to the electromagnets, and the culture solution container is taken out of the storage cavity. By arranging the automatic clamping mechanism, manual operation of the user is not needed, the two hands of the user are liberated, the user can conveniently take and place the culture solution container through the two hands, operation is easy and convenient, time and labor are saved, and the user can conveniently take and place the culture solution container through the two hands. The taking and placing efficiency of the culture solution container is effectively improved.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The utility model relates to the technical field of oscillators, in particular to a cell culture oscillator. Background Art

[0002] An oscillator is an electronic component used to generate a repetitive electronic signal (usually a sine wave or square wave). The circuit it forms is called an oscillator circuit. An electronic circuit or device that converts direct current into an alternating current signal with a specific frequency is called an oscillator. There are many different types of oscillators. Based on the oscillation excitation method, they can be categorized as self-excited oscillators and externally excited oscillators; based on the circuit structure, they can be divided into RC oscillators, LC oscillators, crystal oscillators, and tuning fork oscillators; and based on the output waveform, they can be categorized as sine, square, and sawtooth waves. Oscillators are widely used in the electronics industry, medical care, scientific research, and other fields.

[0003] For example, Chinese utility model patent No. CN211246323U discloses a cell culture medium oscillator, comprising a bottom fixing frame, a drive motor, a rotating disk, a collision rod, a U-shaped frame, a positioning frame, a rectangular positioning block, a tightening spring, a longitudinal support rod, a transverse storage plate, a side support, a transverse protective frame structure, an auxiliary clamping frame structure, and a storage bucket. A buffer spring is positioned in the middle of the transverse sleeve and contacts the inner side of the limit plate at its left and right ends, thereby tightening the culture medium container inserted into the storage tube. The shaft of the protective cover is connected to the left and right sides of the upper portion of the transverse plate, thereby conveniently protecting the upper end of the container stored in the storage tube during use, thereby preventing the ingress of external dust or the escape of internal liquid.

[0004] The above patent can tighten the culture medium container inserted in the storage tube through the coordinated use of a buffer spring, a limit rod and a tightening rod. However, when the culture medium container is placed in the storage tube, the staff needs to manually bend the tightening rod to one side to facilitate the placement of the culture medium container in the storage tube. As a result, when the staff stores the culture medium container, they need to bend the tightening rod with one hand and use the other hand to take and place the culture medium container. It is impossible to take and place the culture medium container with both hands at the same time, which affects the efficiency of taking and placing the culture medium container. In addition, the above patent is not convenient for adjusting the oscillation amplitude of the culture medium container, and it is difficult to adjust the oscillation amplitude according to specific experimental requirements and cell types. There are certain limitations and it needs to be improved. Utility Model Content

[0005] The purpose of the utility model is to solve the shortcomings of the prior art and to propose a cell culture oscillator.

[0006] In order to achieve the above-mentioned object, the present invention adopts the following technical solution: a cell culture oscillator, comprising a box body, two parallel guide rods fixedly connected between the two sides of the inner wall of the box body, an oscillating plate slidably sleeved between the outer surfaces of the two guide rods, a driving mechanism for driving the oscillating plate to move back and forth is further provided inside the box body, a storage rack is fixedly connected to the top of the oscillating plate, a plurality of storage cavities distributed in a rectangular array are defined on the top of the storage rack, a device slot is defined on the top of the storage rack and on both sides of each storage cavity, and a clamping mechanism is provided inside the device slot;

[0007] The clamping mechanism includes a device box embedded in the device slot, an electromagnet is fixedly connected to the side of the device box away from the storage cavity, and a permanent magnet is slidably connected to the inside of the device box, a telescopic rod is fixedly connected to the side of the permanent magnet away from the electromagnet, and the other end of the telescopic rod movably passes through the device box and is fixedly connected to a splint.

[0008] As a further description of the above technical solution: buffer rubber pads are fixedly connected to both sides of the permanent magnet.

[0009] As a further description of the above technical solution: the driving mechanism includes a driving motor and a nut fixedly mounted on the box body, the output end of the driving motor is fixedly connected to a rotating shaft, an oscillation wheel is hingedly mounted on the outer surface of the rotating shaft, an oscillation ball is movably inserted inside the oscillation wheel, the top of the oscillation ball is fixedly connected to the middle position of the bottom of the oscillation plate through a connecting block, the outer surface of the rotating shaft is also fixedly connected to a limiting bar, an adjusting wheel 1 is slidingly sleeved between the outer surfaces of the rotating shaft and the limiting bar, and a connecting rod is hingedly mounted between the adjusting wheel 1 and the oscillation wheel.

[0010] As a further description of the above technical solution: the internal thread of the nut is connected to a threaded adjustment rod, one end of the threaded adjustment rod movably passes through the box and is rotatably connected to an adjusting wheel 2, and the adjusting wheel 2 is movably inserted into the interior of the adjusting wheel 1.

[0011] As a further description of the above technical solution: one end of the threaded adjustment rod away from the second adjustment wheel is fixedly connected to a handwheel.

[0012] As a further description of the above technical solution: a door is hingedly installed on the front of the box body, and a transparent observation window is embedded in the door.

[0013] As a further description of the above technical solution: a folding light-proof curtain is further provided on the door at a position corresponding to the transparent observation window, and one end of the folding light-proof curtain is fixedly connected to a moving rod.

[0014] As a further description of the above technical solution: a control panel is also provided on the front of the box.

[0015] The utility model has the following beneficial effects:

[0016] 1. Compared with the existing technology, when the cell culture oscillator needs to take the culture medium container into the storage chamber, the power supply of all electromagnets is turned off through the control panel, the magnetism of the electromagnet disappears, and the electromagnet is magnetically attracted by the permanent magnet. The electromagnet is fixedly connected to the device box, so that the permanent magnet moves to the side close to the electromagnet, and drives the clamping plate to exit the storage chamber and release the clamping of the culture medium container, which is convenient for the user to take the culture medium container into the storage chamber. Through the setting of the automatic clamping mechanism, the user does not need to operate manually, freeing both hands, making it convenient for the user to take and place the culture medium container with both hands. The operation is simple and convenient, saving time and effort, and effectively improving the efficiency of taking and placing the culture medium container.

[0017] 2. Compared with the existing technology, this cell culture oscillator drives the threaded adjustment rod to rotate and move inside the nut by manually holding the handwheel and twisting it. The movement of the threaded adjustment rod can drive the adjustment wheel 2 to move, thereby pushing the adjustment wheel 1 to move, and driving the oscillation wheel to rotate through the connecting rod, so as to adjust the inclination angle of the oscillation wheel. The inclination angle of the oscillation wheel is proportional to the oscillation amplitude of the vibration plate, thereby realizing the adjustment of the oscillation amplitude according to specific experimental requirements and cell types, thereby improving the adaptability of the device. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 This is a three-dimensional schematic diagram of the overall structure of a cell culture oscillator proposed in the present invention;

[0019] Figure 2 This is a schematic diagram of the structure of a cell culture oscillator including a driving motor and a storage rack proposed in the utility model;

[0020] Figure 3 This is a schematic diagram of the structure of an oscillating plate and oscillating wheel of a cell culture oscillator proposed in the utility model;

[0021] Figure 4 This is a cross-sectional view of the storage rack and storage cavity of a cell culture oscillator proposed in the utility model;

[0022] Figure 5 for Figure 4 Enlarged view of point A in the middle;

[0023] Figure 6 This is a schematic diagram of the driving mechanism of a cell culture oscillator proposed in the utility model.

[0024] Legend:

[0025] 1. Box body; 2. Guide rod; 3. Oscillating plate; 4. Storage rack; 5. Storage chamber; 6. Device box; 7. Electromagnet; 8. Permanent magnet; 9. Telescopic rod; 10. Clamp; 11. Buffer pad; 12. Control panel; 13. Drive motor; 14. Nut; 15. Rotating shaft; 16. Oscillating wheel; 17. Oscillating ball; 18. Limiting strip; 19. Adjusting wheel 1; 20. Connecting rod; 21. Threaded adjusting rod; 22. Adjusting wheel 2; 23. Handwheel; 24. Box door; 25. Transparent observation window; 26. Folding light-proof curtain; 27. Moving rod. DETAILED DESCRIPTION

[0026] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0027] Reference Figure 1-6 The utility model provides a cell culture oscillator: it includes a box body 1, two parallel guide rods 2 are fixedly connected between the two sides of the inner wall of the box body 1, an oscillation plate 3 is slidably sleeved between the outer surfaces of the two guide rods 2, and a driving mechanism for driving the oscillation plate 3 to move back and forth is further provided inside the box body 1, a storage rack 4 is fixedly connected to the top of the oscillation plate 3, a plurality of storage cavities 5 distributed in a rectangular array are opened on the top of the storage rack 4, a device slot is opened on the top of the storage rack 4 and on both sides of each storage cavity 5, and a clamping mechanism is provided inside the device slot;

[0028] The clamping mechanism includes a device box 6 embedded in the device slot, an electromagnet 7 is fixedly connected to the side of the device box 6 away from the storage cavity 5, and a permanent magnet 8 is slidably connected to the inside of the device box 6, a telescopic rod 9 is fixedly connected to the side of the permanent magnet 8 away from the electromagnet 7, the other end of the telescopic rod 9 is movable through the device box 6 and is fixedly connected to a splint 10, and buffering rubber pads 11 are fixedly connected to both sides of the permanent magnet 8. The setting of the buffering rubber pads 11 can play a buffering role when the permanent magnet 8 moves, preventing the permanent magnet 8 from violently colliding with the electromagnet 7 or the inner wall of the device box 6, thereby causing damage.

[0029] The driving mechanism includes a driving motor 13 and a nut 14 fixedly mounted on the box body 1. The output end of the driving motor 13 is fixedly connected to a rotating shaft 15. An oscillation wheel 16 is hingedly mounted on the outer surface of the rotating shaft 15. An oscillation ball 17 is movably inserted inside the oscillation wheel 16. The top of the oscillation ball 17 is fixedly connected to the middle position of the bottom of the oscillation plate 3 through a connecting block. The outer surface of the rotating shaft 15 is also fixedly connected to a limiting bar 18. An adjusting wheel 19 is slidingly sleeved between the outer surfaces of the rotating shaft 15 and the limiting bar 18. The setting of the limiting bar 18 can limit the adjusting wheel 19, so that the adjusting wheel 19 can only move along the axial direction of the rotating shaft 15. A connecting rod 20 is hingedly mounted between the adjusting wheel 19 and the oscillation wheel 16.

[0030] The internal thread of the nut 14 is connected to a threaded adjustment rod 21, one end of the threaded adjustment rod 21 movably passes through the box body 1 and is rotatably connected to an adjustment wheel 22, which is movably inserted into the interior of the adjustment wheel 19;

[0031] By rotating the threaded adjustment rod 21 to make it move inside the nut 14, the adjustment wheel 2 22 is driven to move, thereby pushing the adjustment wheel 1 19 to move through the movement of the adjustment wheel 22, and driving the oscillation wheel 16 to rotate through the connecting rod 20, thereby adjusting the inclination angle of the oscillation wheel 16, and the inclination angle of the oscillation wheel 16 is proportional to the oscillation amplitude of the vibration plate, thereby realizing the adjustment of the oscillation amplitude according to specific experimental requirements and cell types, thereby improving the adaptability of the device.

[0032] One end of the threaded adjustment rod 21 away from the second adjustment wheel 22 is fixedly connected to a hand wheel 23 , and the hand wheel 23 is provided to facilitate the user to screw the threaded adjustment rod 21 .

[0033] A door 24 is hingedly installed on the front of the box body 1, and a transparent observation window 25 is embedded in the door 24. A folding light-proof curtain 26 is also provided at the position corresponding to the transparent observation window 25 on the door 24. One end of the folding light-proof curtain 26 is fixedly connected to a moving rod 27. The setting of the transparent observation window 25 makes it convenient for the staff to observe the internal situation of the box body 1. By unfolding the folding light-proof curtain 26, the position of the transparent observation window 25 on the door 24 can be blocked to facilitate the light-proof culture of cells.

[0034] A control panel 12 is further provided on the front of the box body 1 , and the control panel 12 is electrically connected to the electromagnet 7 and the drive motor 13 respectively.

[0035] Working principle: During use, when it is necessary to take or place the culture solution container in the storage chamber 5, the user first opens the box door 24, and then turns off the power of all electromagnets 7 through the control panel 12. After the power is turned off, the magnetism of the electromagnet 7 disappears, and thus the repulsive force on the permanent magnet 8 disappears. At this time, the electromagnet 7 is attracted by the magnetic force of the permanent magnet 8 itself, and the electromagnet 7 is fixedly connected to the device box 6, so that the permanent magnet 8 moves to the side close to the electromagnet 7, and the clamping plate 10 is driven by the telescopic rod 9 to move toward the inside of the device slot, that is, to exit the storage chamber 5 and release the clamping fixation of the culture solution container, so that the user can take or place the culture solution container in the storage chamber 5. Through the setting of the automatic clamping mechanism, there is no need for manual operation by the user, freeing both hands, and it is convenient for the user to take or place the culture solution container with both hands. The operation is simple and convenient, saving time and effort, and effectively improving the efficiency of taking or placing the culture solution container.

[0036] When the culture medium container that needs to be oscillated is placed in the storage chamber 5, the electromagnet 7 is energized through the control panel 12, and the electromagnet 7 generates magnetism. The opposite magnetic poles of the electromagnet 7 and the permanent magnet 8 are the same. According to the principle of like magnetic poles repelling each other, a repulsive force is generated on the permanent magnet 8, causing the permanent magnet 8 to move to the side away from the electromagnet 7, and the splint 10 is driven by the telescopic rod 9 to move to the side close to the culture medium container stored in the storage chamber 5, so that the culture medium container is clamped and fixed by the splint 10, thereby improving the stability of the culture medium container;

[0037] Then, the door 24 is closed. If light-shielded culture is required, the user holds the moving rod 27 and moves it, thereby unfolding the folded light-shielding curtain 26 to block the position of the transparent observation window 25 on the door 24, so as to facilitate light-shielded culture of cells.

[0038] Next, the user adjusts the oscillation amplitude of the oscillation plate 3 (i.e., adjusts the tilt angle of the oscillation wheel 16) according to specific experimental requirements and cell types. The user holds the handgrip 23 and twists it, driving the threaded adjustment rod 21 to rotate and move inside the nut 14. The movement of the threaded adjustment rod 21 drives the adjustment wheel 2 22 to move, thereby driving the adjustment wheel 1 19 to move, and driving the oscillation wheel 16 to rotate through the connecting rod 20, thereby adjusting the tilt angle of the oscillation wheel 16. The tilt angle of the oscillation wheel 16 is proportional to the oscillation amplitude of the vibration plate.

[0039] When the inclination angle of the oscillation wheel 16 is adjusted, the drive motor 13 is started through the control panel 12, and the output end of the drive motor 13 rotates, driving the rotating shaft 15 to rotate, and then driving the oscillation wheel 16 to rotate. Since the oscillation wheel 16 is in a tilted state, it will drive the oscillation ball 17 to move left and right during its rotation, thereby driving the vibration plate to move back and forth left and right, thereby realizing the oscillation of the culture medium container placed on the storage rack 4.

[0040] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or make equivalent replacements for some of the technical features therein. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

Claims

1. A cell culture oscillator, comprising a housing (1), characterized in that: Two parallel guide rods (2) are fixedly connected between the two sides of the inner wall of the box (1), an oscillating plate (3) is slidably sleeved between the outer surfaces of the two guide rods (2), and a driving mechanism for driving the oscillating plate (3) to move back and forth is also provided inside the box (1), a storage rack (4) is fixedly connected to the top of the oscillating plate (3), a plurality of storage cavities (5) distributed in a rectangular array are provided on the top of the storage rack (4), and a device groove is provided on both sides of each storage cavity (5), and a clamping mechanism is provided inside the device groove; The clamping mechanism comprises a device box (6) embedded in the device slot, an electromagnet (7) is fixedly connected to the side of the device box (6) away from the storage cavity (5), and a permanent magnet (8) is slidably connected to the inside of the device box (6), a telescopic rod (9) is fixedly connected to the side of the permanent magnet (8) away from the electromagnet (7), and the other end of the telescopic rod (9) movably passes through the device box (6) and is fixedly connected to a clamping plate (10).

2. A cell culture oscillator according to claim 1, characterized in that: Buffering rubber pads (11) are fixedly connected to both sides of the permanent magnet (8).

3. A cell culture oscillator according to claim 1, characterized in that: The driving mechanism comprises a driving motor (13) and a nut (14) fixedly mounted on the box body (1); an output end of the driving motor (13) is fixedly connected to a rotating shaft (15); an oscillating wheel (16) is hingedly mounted on the outer surface of the rotating shaft (15); an oscillating ball (17) is movably inserted inside the oscillating wheel (16); the top end of the oscillating ball (17) is fixedly connected to the middle position of the bottom of the oscillating plate (3) through a connecting block; the outer surface of the rotating shaft (15) is also fixedly connected to a limiting strip (18); an adjusting wheel (19) is slidingly sleeved between the outer surfaces of the rotating shaft (15) and the limiting strip (18); and a connecting rod (20) is hingedly mounted between the adjusting wheel (19) and the oscillating wheel (16).

4. A cell culture oscillator according to claim 3, characterized in that: The internal thread of the nut (14) is connected to a threaded adjustment rod (21), one end of which movably passes through the box body (1) and is rotatably connected to an adjustment wheel 2 (22), and the adjustment wheel 2 (22) is movably inserted into the interior of the adjustment wheel 1 (19).

5. A cell culture oscillator according to claim 4, characterized in that: One end of the threaded adjustment rod (21) away from the second adjustment wheel (22) is fixedly connected to a hand wheel (23).

6. The cell culture oscillator according to claim 1, characterized in that: A box door (24) is hingedly mounted on the front of the box body (1), and a transparent observation window (25) is embedded in the box door (24).

7. A cell culture oscillator according to claim 6, characterized in that: A folding light-proof curtain (26) is also provided at a position corresponding to the transparent observation window (25) on the box door (24), and one end of the folding light-proof curtain (26) is fixedly connected to a moving rod (27).

8. The cell culture oscillator according to claim 1, characterized in that: A control panel (12) is also provided on the front of the box (1).

Citation Information

Patent Citations

  • Oscillator for cell culture solution

    CN211246323U