Sampling device for CTC enrichment detection

Abstract

The utility model discloses a sampling device for CTC enrichment detection, which relates to the technical field of CTC enrichment, and adopts the technical scheme that the sampling device comprises a positioning plate of a cuboid structure, a positioning mechanism arranged at the top of the positioning plate and used for positioning a plurality of sampling test tubes, and a protection mechanism arranged on the outer side of the positioning mechanism, the positioning mechanism is used for positioning a sampling test tube, the protection mechanism is used for protecting the positioned sampling test tube, the positioning mechanism comprises two supporting frames, the two supporting frames are fixedly connected to the top of the positioning plate, and a supporting plate is fixedly connected to the tops of the two supporting frames. Meanwhile, the device adopts an electrically-controlled electric push rod to provide power, so that the device is more accurately controlled, and in addition, the device adopts a structure of a plurality of springs, so that a plurality of buffer plates cannot rigidly clamp the test tube, and the test tube is prevented from being broken.

Description

Technical Field

[0001] The utility model relates to the technical field of CTC enrichment, and in particular to a sampling device for CTC enrichment detection. Background Art

[0002] The number of CTCs in the human circulatory system is extremely low, with only 1 to 10 CTCs per milliliter of whole blood in patients with tumor metastasis. Therefore, sorting and enriching CTCs is a critical step in detecting and enriching them. The effectiveness of CTC sorting and enrichment directly affects the effectiveness of subsequent detection. Therefore, high-purity, high-sensitivity (no CTC loss), rapid, and highly viable CTC sorting and enrichment technologies are key to the clinical application of CTCs.

[0003] In the existing CTC enrichment process, the patient's blood needs to be sampled and tested. The existing sampling devices generally store and collect blood through test tubes. However, since the test tubes are relatively fragile, they may be accidentally touched during storage, causing the test tubes to rupture and the blood sample to be lost. Summary of the Invention

[0004] To this end, the present invention provides a sampling device for CTC enrichment detection. The user places the sampling test tube into the positioning groove inside the support plate, starts multiple electric push rods to operate, and makes the protective mechanism work, so that the protective plate and the support plate are spliced, and multiple buffer plates clamp and protect the test tube, so as to solve the problem that the existing sampling devices generally use test tubes for storage and collection, but because the test tubes are relatively fragile, they may be broken by accidental touch during storage, resulting in the loss of blood samples.

[0005] In order to achieve the above-mentioned purpose, the present invention provides the following technical solutions: a sampling device for CTC enrichment detection, comprising

[0006] A positioning plate, wherein the positioning plate is configured as a rectangular parallelepiped structure;

[0007] A positioning mechanism, which is provided on the top of the positioning plate and is used to position a plurality of sampling test tubes;

[0008] A protection mechanism, the protection mechanism being arranged outside the positioning mechanism and being used to protect the positioned sampling tube;

[0009] The positioning mechanism includes two support frames, both of which are fixedly connected to the top of the positioning plate. The tops of the two support frames are fixedly connected to a supporting plate, and the tops of the supporting plates are provided with positioning grooves.

[0010] Preferably, the protection mechanism includes two sliding blocks, both of which are arranged on the top of the positioning plate, and the top ends of the two sliding blocks are fixedly connected to a telescopic rod.

[0011] Preferably, the protection mechanism further includes a protection plate, which is arranged on the top of the supporting plate, and the protection plate is movably connected to the supporting plate through a hinge.

[0012] Preferably, the front and rear sides of the protective plate are fixedly connected with positioning rods, and the two positioning rods are respectively embedded in the outsides of the two telescopic rods and movably connected to the telescopic rods through rolling bearings.

[0013] Preferably, the protective mechanism further includes a plurality of buffer plates, wherein the plurality of buffer plates are all arranged inside the protective plate, the tops of the plurality of buffer plates are all fixedly connected with lifting rods, and the tops of the plurality of lifting rods extend to the outside of the top of the protective plate.

[0014] Preferably, a transverse plate is provided on the top of the protective plate, the transverse plate is fixedly connected to the tops of the plurality of lifting rods, and two springs are fixedly connected to the bottom of the transverse plate, and both springs are fixedly connected to the top of the protective plate.

[0015] Preferably, the protection mechanism further includes a plurality of electric push rods, and the plurality of electric push rods are all arranged on the top of the positioning plate. The top of the positioning plate is fixedly connected to two fixing plates, and the two fixing plates are respectively fixedly connected to the outer ends of the plurality of electric push rods.

[0016] Preferably, two movable plates are provided on the top of the positioning plate, and the plurality of movable plates are respectively fixedly connected to the inner ends of the plurality of electric push rods, and the plurality of movable plates are respectively fixedly connected to the two sliding blocks.

[0017] Preferably, two limiting rods are fixedly connected between the two fixing plates, and the two limiting rods are respectively embedded in the two sliding blocks and slide with the sliding blocks.

[0018] Preferably, an electric heater is embedded in the support plate.

[0019] The beneficial effects of the utility model are:

[0020] The user places the sampling test tube into the positioning groove inside the support plate, starts multiple electric push rods, and activates the protective mechanism to make the protective plate and the support plate fit together, and multiple buffer plates clamp and protect the test tube, so as to solve the problem that the existing sampling device generally uses test tubes for storage and collection, but since the test tubes are relatively fragile, they may be broken due to accidental touch during storage, resulting in loss of blood samples. The utility model greatly improves the efficiency of protecting blood test tube samples. At the same time, the device adopts an electrically controlled electric push rod to provide power, which makes the device control more accurate. In addition, the device adopts a structure of multiple springs, so that the multiple buffer plates will not rigidly clamp the test tube, preventing the test tube from breaking and greatly protecting the blood sample. At the same time, the design of the electric heater prevents blood from coagulation at low temperatures. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] To more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for the embodiments or the description of the prior art. Obviously, the drawings described below are merely illustrative, and those skilled in the art can, without inventive effort, derive other implementation drawings from the provided drawings.

[0022] The structures, proportions, sizes, etc. illustrated in this specification are intended solely to complement the contents disclosed herein and to facilitate understanding and reading by persons familiar with the art. They are not intended to limit the conditions under which the present invention may be implemented and therefore have no substantive technical significance. Any structural modifications, changes in proportions, or adjustments in size, provided they do not affect the efficacy and objectives of the present invention, shall remain within the scope of the technical contents disclosed herein.

[0023] Figure 1 A schematic diagram of the overall structure provided by the utility model;

[0024] Figure 2 A front view and a cross-sectional view provided for the present utility model;

[0025] Figure 3 This is a schematic diagram of the three-dimensional structure of the electric push rod and telescopic rod provided by the utility model;

[0026] Figure 4 A schematic diagram of the three-dimensional structure of the support plate provided by the utility model;

[0027] Figure 5 A schematic diagram of the three-dimensional structure of the protective plate and buffer plate provided by the utility model;

[0028] In the figure: 1 positioning plate; 2 support frame; 3 support plate; 4 positioning groove; 5 sliding block; 6 telescopic rod; 7 protective plate; 8 positioning rod; 9 buffer plate; 10 lifting rod; 11 horizontal plate; 12 spring; 13 electric push rod; 14 fixed plate; 15 movable plate; 16 limit rod; 17 electric heater. DETAILED DESCRIPTION

[0029] The preferred embodiments of the present invention are described below in conjunction with the accompanying drawings. It should be understood that the preferred embodiments described herein are only used to illustrate and explain the present invention and are not used to limit the present invention.

[0030] Refer to the attached Figure 1 -Attached Figure 5 The utility model provides a sampling device for CTC enrichment detection, comprising

[0031] Positioning plate 1, the positioning plate 1 is set as a rectangular parallelepiped structure;

[0032] Positioning mechanism, the positioning mechanism is arranged on the top of the positioning plate 1, and the positioning mechanism is used to position multiple sampling tubes;

[0033] The protection mechanism is arranged outside the positioning mechanism and is used to protect the positioned sampling tube;

[0034] The positioning mechanism includes two support frames 2, both of which are fixedly connected to the top of the positioning plate 1. The tops of the two support frames 2 are fixedly connected to a supporting plate 3, and the tops of the supporting plates 3 are provided with a positioning slot 4;

[0035] In this embodiment, the user places the sample tube into the positioning groove 4 inside the support plate 3, and activates the multiple electric push rods 13 to operate, so that the protection mechanism is activated, so that the protection plate 7 and the support plate 3 are spliced ​​together, and the multiple buffer plates 9 clamp and protect the tube;

[0036] Among them, in order to achieve the purpose of test tube sample protection, this device adopts the following technical solutions: the protection mechanism includes two sliding blocks 5, the two sliding blocks 5 are both arranged on the top of the positioning plate 1, and the tops of the two sliding blocks 5 are fixedly connected to the telescopic rod 6, the protection mechanism also includes a protection plate 7, the protection plate 7 is arranged on the top of the support plate 3, the protection plate 7 and the support plate 3 are movably connected by a hinge, the front and rear sides of the protection plate 7 are fixedly connected to the positioning rod 8, the two positioning rods 8 are respectively embedded in the outside of the two telescopic rods 6 and are movably connected to the telescopic rod 6 through rolling bearings, the protection mechanism also includes a plurality of buffer plates 9, the plurality of buffer plates 9 are all arranged inside the protective plate 7, the tops of the plurality of buffer plates 9 are fixedly connected to the lifting rod 10, the tops of the plurality of lifting rods 10 extend to the outside of the top of the protective plate 7, the top of the protective plate 7 A transverse plate 11 is provided, which is fixedly connected to the tops of the multiple lifting rods 10, and two springs 12 are fixedly connected to the bottom of the transverse plate 11, and the two springs 12 are fixedly connected to the top of the protective plate 7. The protective mechanism also includes a plurality of electric push rods 13, and the plurality of electric push rods 13 are all provided on the top of the positioning plate 1. Two fixed plates 14 are fixedly connected to the top of the positioning plate 1, and the two fixed plates 14 are respectively fixedly connected to the outer ends of the plurality of electric push rods 13. Two movable plates 15 are provided on the top of the positioning plate 1, and the plurality of movable plates 15 are respectively fixedly connected to the inner ends of the plurality of electric push rods 13. The plurality of movable plates 15 are respectively fixedly connected to the two sliding blocks 5. Two limiting rods 16 are fixedly connected between the two fixed plates 14, and the two limiting rods 16 are respectively embedded in the two sliding blocks 5 and slide on the sliding blocks 5.

[0037] The user controls the electric push rod 13 to work, and the corresponding two electric push rods 13 work in opposite directions. The operation of multiple electric push rods 13 causes the movable plate 15 and the limit block to move. The movement of the limit block drives the telescopic rod 6 to move. The movement of the telescopic rod 6 drives the positioning rod 8 to move. The movement of the positioning rod 8 can drive the protective plate 7 to rotate around the hinge as the center of the circle to realize the closing and opening of the protective plate 7. When the buffer plate 9 contacts the test tube, the spring 12 rebounds to buffer the multiple test tubes to prevent the test tubes from being damaged.

[0038] In order to achieve the purpose of heating the sample, the device adopts the following technical solutions: an electric heater 17 is embedded in the support plate 3;

[0039] The user starts the electric heater 17 to heat the test tubes in the different positioning grooves 4 to prevent the blood inside the test tubes from clotting.

[0040] The usage process of the present utility model is as follows: the user places the sampling test tube into the positioning groove 4 inside the support plate 3, starts multiple electric push rods 13 to work, so that the protective mechanism works, so that the protective plate 7 is spliced ​​with the support plate 3, and multiple buffer plates 9 clamp and protect the test tube. The user controls the electric push rod 13 to work, and the corresponding two electric push rods 13 work in opposite directions. The multiple electric push rods 13 work to move the movable plate 15 and the limit block. The movement of the limit block drives the telescopic rod 6 to move, and the movement of the telescopic rod 6 drives the positioning rod 8 to move. The movement of the positioning rod 8 can drive the protective plate 7 to rotate with the hinge as the center of the circle to realize the closing and opening of the protective plate 7. When the buffer plate 9 contacts the test tube, the spring 12 rebounds to buffer the multiple test tubes to prevent the test tube from being damaged. The user starts the electric heater 17 to work, and the electric heater 17 works to heat the test tubes inside different positioning grooves 4 to prevent blood coagulation inside the test tube.

[0041] The above description is merely a preferred embodiment of the present invention. Anyone skilled in the art may utilize the above-described technical solutions to modify the present invention or create equivalent technical solutions. Therefore, any simple modification or equivalent replacement based on the technical solutions of the present invention falls within the scope of protection claimed by the present invention.

Claims

1. A sampling device for CTC enrichment detection, characterized by: include A positioning plate (1), wherein the positioning plate (1) is configured as a rectangular parallelepiped structure; A positioning mechanism, the positioning mechanism being arranged on the top of the positioning plate (1) and being used for positioning a plurality of sampling test tubes; A protection mechanism, the protection mechanism being arranged outside the positioning mechanism and being used to protect the positioned sampling tube; The positioning mechanism comprises two support frames (2), both of the support frames (2) are fixedly connected to the top of the positioning plate (1), the tops of the two support frames (2) are fixedly connected to a supporting plate (3), and the tops of the supporting plates (3) are provided with a positioning groove (4).

2. A sampling device for CTC enrichment detection according to claim 1, characterized in that: The protection mechanism comprises two sliding blocks (5), both of which are arranged on the top of the positioning plate (1), and the top ends of the two sliding blocks (5) are fixedly connected to a telescopic rod (6).

3. The sampling device for CTC enrichment detection according to claim 1, characterized in that: The protection mechanism further comprises a protection plate (7), wherein the protection plate (7) is arranged on the top of the support plate (3), and the protection plate (7) is movably connected to the support plate (3) via a hinge.

4. A sampling device for CTC enrichment detection according to claim 3, characterized in that: Positioning rods (8) are fixedly connected to both the front and rear sides of the protective plate (7), and the two positioning rods (8) are respectively embedded in the outsides of the two telescopic rods (6) and are movably connected to the telescopic rods (6) through rolling bearings.

5. The sampling device for CTC enrichment detection according to claim 1, characterized in that: The protective mechanism further comprises a plurality of buffer plates (9), the plurality of buffer plates (9) being arranged inside the protective plate (7), the tops of the plurality of buffer plates (9) being fixedly connected to lifting rods (10), the tops of the plurality of lifting rods (10) being extended to the outside of the top of the protective plate (7).

6. The sampling device for CTC enrichment detection according to claim 4, characterized in that: A transverse plate (11) is provided on the top of the protective plate (7), and the transverse plate (11) is fixedly connected to the tops of the plurality of lifting rods (10). Two springs (12) are fixedly connected to the bottom of the transverse plate (11), and both of the two springs (12) are fixedly connected to the top of the protective plate (7).

7. The sampling device for CTC enrichment detection according to claim 2, characterized in that: The protection mechanism further comprises a plurality of electric push rods (13), each of which is arranged on the top of the positioning plate (1), and two fixing plates (14) are fixedly connected to the top of the positioning plate (1), and the two fixing plates (14) are respectively fixedly connected to the outer ends of the plurality of electric push rods (13).

8. The sampling device for CTC enrichment detection according to claim 4, characterized in that: Two movable plates (15) are provided on the top of the positioning plate (1), and the plurality of movable plates (15) are respectively fixedly connected to the inner ends of the plurality of electric push rods (13), and the plurality of movable plates (15) are respectively fixedly connected to the two sliding blocks (5).

9. The sampling device for CTC enrichment detection according to claim 7, characterized in that: Two limiting rods (16) are fixedly connected between the two fixing plates (14), and the two limiting rods (16) are respectively embedded in the two sliding blocks (5) and slide on the sliding blocks (5).

10. The sampling device for CTC enrichment detection according to claim 1, characterized in that: An electric heater (17) is embedded inside the support plate (3).

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