Automatic sampling device for drug absorption and penetration test

Abstract

The utility model relates to the technical field of medicine sampling, in particular to an automatic sampling device for a medicine absorption and penetration test, which comprises a workstation, a conveying rack and a conveying belt, and further comprises a positioning component, and the positioning component comprises a sample pool, a positioning block, a trigger block, a support bracket, a fixed seat, a sensor, an indicator light and a locking component, the sample pool is arranged on the conveying belt, the positioning block is fixedly connected with the sample pool, the trigger block is fixedly connected with the positioning block, the supporting bracket is fixedly connected with the conveying rack, the fixing seat is fixedly connected with the supporting bracket, the sensor is arranged on the fixing seat, the indicator lamp is arranged on the supporting bracket, and the locking component is arranged on the conveying rack. The trigger block triggers the sensor and starts the indicator light to light and the conveyor belt to stop, so that the position of the sample pool is quickly positioned and moved to the collection position of the workstation for collection, and the situation that the sample pool and the collection position of the workstation need to be manually positioned for a long time is avoided.

Description

Technical Field

[0001] The utility model relates to the technical field of drug sampling, in particular to an automatic sampling device for drug absorption and penetration testing. Background Art

[0002] With the rapid development of the pharmaceutical industry and biopharmaceutical technology, the study of drug absorption and permeability has become increasingly important during drug development. Traditional drug absorption and permeability testing methods typically require manual operation, which is time-consuming, labor-intensive, and prone to human error, affecting the accuracy and reproducibility of test results.

[0003] The equipment in the prior art integrates a drug absorption and permeation test incubation device and an automated sampling technology. The equipment includes multiple sample pools, artificial membrane components, and multiple receiving pools on a base to form a multi-channel system that can test multiple samples simultaneously. At the same time, it can be quickly disassembled, the reaction can be terminated, and the cleaning can be done. Through the automated sampling system, the automated sampling process of the drug absorption and permeation test process is realized. Through automated operation, the influence of human factors on the test results is reduced, and the repeatability and consistency of the test results are improved.

[0004] However, during the collection process, the existing equipment does not have a positioning mechanism to quickly locate the placement of the sample pool, so it takes a long time of manual labor to locate the sample pool and the workstation collection position. Utility Model Content

[0005] The purpose of the utility model is to provide an automated sampling device for drug absorption and permeation testing, aiming to solve the problem that in the existing equipment, there is no positioning mechanism to quickly locate the placement position of the sample pool during the collection process, thereby requiring a long time of manual labor to locate the sample pool and the workstation collection position.

[0006] To achieve the above-mentioned purpose, the utility model provides an automated sampling device for drug absorption and permeation testing, comprising a workstation, a conveyor frame and a conveyor belt, wherein the conveyor frame is arranged on the workstation and is located on one side of the workstation, and the conveyor belt is arranged on the conveyor frame and is located on one side of the conveyor frame.

[0007] Also includes positioning components,

[0008] The positioning assembly includes a sample pool, a positioning block, a trigger block, a support bracket, a fixing seat, a sensor, an indicator light and a locking member. The sample pool is arranged on the conveyor belt and is located on one side of the conveyor belt. The positioning block is fixedly connected to the sample pool and is located on one side of the sample pool. The trigger block is arranged and fixedly connected to the positioning block and is located on one side of the positioning block. The support bracket is fixedly connected to the conveyor frame and is located on one side of the conveyor frame. The fixing seat is fixedly connected to the support bracket and is located on one side of the support bracket. The sensor is arranged on the fixing seat and is located on a side of the fixing seat close to the trigger block. The indicator light is arranged on the support bracket and is located on one side of the support bracket. The locking member is arranged on the conveyor frame.

[0009] In which, the locking component includes a directional rod, a sliding block, a screw, an abutment plate and a rotating component, the directional rod is fixedly connected to the conveying frame and is located on one side of the conveying frame; the sliding block is slidably connected to the directional rod and is located on one side of the directional rod; the screw is connected to the directional rod through the rotating component and is threadedly connected to the sliding block; the abutment plate is fixedly connected to the sliding block and is located on a side of the sliding block close to the sample pool, and the rotating component is arranged on the directional rod and connected to the screw.

[0010] Among them, the rotating component includes a mounting seat and a rotating motor, the mounting seat is fixedly connected to the directional rod and is located on one side of the directional rod; the rotating motor is fixedly connected to the mounting seat and connected to the screw rod, and is located on the side of the mounting seat close to the screw rod.

[0011] Wherein, the positioning assembly further includes a protective cover, which is fixedly connected to the support bracket and is located on a side of the support bracket close to the indicator light.

[0012] In which, the locking member also includes a supporting component, which includes a supporting base and a rotating disk. The supporting base is fixedly connected to the conveying frame and is located on one side of the conveying frame; the rotating disk is rotatably connected to the supporting base and fixedly connected to the screw, and is located on the side of the supporting base close to the screw.

[0013] The utility model provides an automated sampling device for drug absorption and penetration testing. When the sample pool is transported by the conveyor belt, the trigger block on the positioning block of the sample pool moves to directly below the sensor, so that the trigger block triggers the sensor and starts the indicator light to light up and the conveyor belt to stop, so that the position of the sample pool is quickly positioned and moved to the workstation collection position for collection, avoiding the need for manual labor to spend a long time to position the sample pool and the workstation collection position. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art.

[0015] Figure 1 It is a structural schematic diagram of the automatic sampling device for drug absorption and permeation testing according to the first embodiment of the present utility model.

[0016] Figure 2 It is a schematic structural diagram of the sample pool of the first embodiment of the present utility model.

[0017] Figure 3 It is a structural schematic diagram of the support bracket of the first embodiment of the present utility model.

[0018] Figure 4 It is a structural schematic diagram of the locking member of the first embodiment of the present utility model.

[0019] Figure 5 It is a structural schematic diagram of an automated sampling device for drug absorption and permeation testing according to the second embodiment of the present invention.

[0020] In the figure: 101-workstation, 102-transfer rack, 103-conveyor belt, 104-sample pool, 105-positioning block, 106-trigger block, 107-support bracket, 108-fixed seat, 109-sensor, 110-indicator light, 111-protective cover, 112-directional rod, 113-sliding block, 114-screw, 115-abutment plate, 116-mounting seat, 117-rotating motor, 201-support component, 202-support base, 203-rotating disk. DETAILED DESCRIPTION

[0021] The embodiments of the present invention are described in detail below, and examples of the embodiments are shown in the accompanying drawings. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to be used to explain the present invention, but should not be understood as limiting the present invention.

[0022] The first embodiment of this application is:

[0023] See also Figures 1 to 4,in Figure 1 It is a structural schematic diagram of the automatic sampling device for drug absorption and permeation testing according to the first embodiment of the present utility model. Figure 2 It is a schematic structural diagram of the sample pool of the first embodiment of the present utility model. Figure 3 It is a structural schematic diagram of the support bracket of the first embodiment of the present utility model. Figure 4 It is a structural schematic diagram of the locking member of the first embodiment of the present utility model.

[0024] The present invention provides an automated sampling device for drug absorption and permeation testing, comprising a workstation 101, a conveyor frame 102, a conveyor belt 103, and a positioning assembly, wherein the positioning assembly comprises a sample pool 104, a positioning block 105, a trigger block 106, a support bracket 107, a fixing seat 108, a sensor 109, an indicator light 110, a locking member, and a protective cover 111, wherein the locking member comprises a directional rod 112, a sliding block 113, a screw 114, an abutment plate 115, and a rotating component, wherein the rotating component comprises a mounting seat 116 and a rotating motor 117. The aforementioned solution solves the problem that, during the collection process, existing equipment lacks a positioning mechanism capable of quickly locating the placement of the sample pool, thereby necessitating a long period of manual labor to locate the sample pool and the workstation collection position. It is understandable that the aforementioned solution can be used in situations where the collection position of the sample pool needs to be quickly located.

[0025] In this embodiment, the conveyor frame 102 is arranged on the workstation 101, and the conveyor belt 103 is arranged on the conveyor frame 102. The driving structure in the conveyor frame 102 can drive the samples on the conveyor belt 103 to be conveyed, and the workstation 101 can collect the samples conveyed on the conveyor belt 103 on the conveyor frame 102.

[0026] The sample pool 104 is arranged on the conveyor belt 103 and is located on one side of the conveyor belt 103. The positioning block 105 is fixedly connected to the sample pool 104 and is located on one side of the sample pool 104. The trigger block 106 is fixedly connected to the positioning block 105 and is located on one side of the positioning block 105. The support bracket 107 is fixedly connected to the conveyor rack 102 and is located on one side of the conveyor rack 102. The fixing seat 108 is fixedly connected to the support bracket 107 and is located on one side of the support bracket 107. The sensor 109 is arranged on the fixing seat 108 and is located on the side of the fixing seat 108 close to the trigger block 106. The indicator light 1 10 is arranged on the supporting bracket 107 and is located on one side of the supporting bracket 107. The locking member is arranged on the conveying rack 102. The sample pool 104 is placed on the conveyor belt 103. There is a single layer of cells at the bottom of the pool of the sample pool 104. The sample pool 104 can be transported to the bottom of the workstation 101 by the conveyor belt 103, and then the sample in the sample pool 104 is collected and tested by the workstation 101. The positioning block 105 is bonded to the center of the sample pool 104. The trigger block 106 is arranged on the positioning block 105. The supporting bracket 107 is welded to the conveying rack 102. The fixing seat 108 is welded to the supporting bracket 107. The support bracket 107 is used to connect the fixing base 108 to the conveyor frame 102 through the support bracket 107. The sensor 109 is provided on the fixing base 108. The sensor 109 is an infrared sensor 109 and can be triggered by the trigger block 106. The indicator light 110 is provided on the support bracket 107. The indicator light 110 has a light-up indication function. When the sample pool 104 is transported by the conveyor belt 103, the trigger block 106 on the positioning block 105 of the sample pool 104 moves to the bottom of the sensor 109. At this time, the position of the sample pool 104 is at the collection position of the workstation 101. At the same time, the trigger block 106 106 triggers the sensor 109 and starts the indicator light 110 to light up and the conveyor belt 103 to stop. The locking member is set on the conveyor frame 102, and the locking member can cooperate with the conveyor belt 103 to clamp and fix both sides of the sample pool 104 of the conveyor belt 103 to prevent the sample pool 104 from moving during the sampling process, thereby achieving that when the sample pool 104 is transported by the conveyor belt 103, the trigger block 106 on the positioning block 105 of the sample pool 104 moves to the bottom of the sensor 109, so that the trigger block 106 triggers the sensor 109 and starts the indicator light 110 to light up and the conveyor belt 103 to stop.The sample pool 104 is quickly positioned and moved to the collection position of the workstation 101 for collection, thus avoiding the need for manual labor to spend a long time to position the sample pool 104 and the collection position of the workstation 101.

[0027] Secondly, the directional rod 112 is fixedly connected to the conveyor frame 102 and is located on one side of the conveyor frame 102; the sliding block 113 is slidably connected to the directional rod 112 and is located on one side of the directional rod 112; the screw 114 is connected to the directional rod 112 through the rotating component and is threadedly connected to the sliding block 113; the abutment plate 115 is fixedly connected to the sliding block 113 and is located on the side of the sliding block 113 close to the sample pool 104, the rotating component is provided on the directional rod 112 and connected to the screw 114, there are four directional rods 112, four directional rods 112 are welded on both sides of the conveyor frame 102, there are two sliding blocks 113, two of the sliding blocks 113 are slidably connected to the four directional rods 112, and the sliding of the sliding block 113 can be directional limited by the directional rod 112, and the screw 1 14 has two, the two screw rods 114 are connected to the directional rod 112 through the rotating component, and the driving output of the rotating component can drive the screw rod 114 to rotate, and the two screw rods 114 are threadedly connected to the corresponding two sliding blocks 113. Under the directional limiting action of the threads of the screw rods 114 and the directional rods 112 on the sliding blocks 113, the screw rods 114 can drive the sliding blocks 113 to move up and down when rotating, and there are four abutment plates 115, which are welded to the corresponding two sliding blocks 113. The movement of the sliding blocks 113 can drive the movement of the abutment plates 115, and then the downward movement of the abutment plates 115 can cooperate with the conveyor belt 103 to clamp and fix the two sides of the sample pool 104 of the conveyor belt 103, so as to prevent the sample pool 104 from moving during the sampling process.

[0028] At the same time, the mounting seat 116 is fixedly connected to the directional rod 112 and is located on one side of the directional rod 112; the rotating motor 117 is fixedly connected to the mounting seat 116 and is connected to the screw 114, and is located on the side of the mounting seat 116 close to the screw 114. There are two mounting seats 116, and the two mounting seats 116 are welded to the corresponding four directional rods 112. There are two rotating motors 117, and the two rotating motors 117 are bolted and fixed in the corresponding two mounting seats 116. The two screws 114 are connected to the output ends of the corresponding two rotating motors 117, so that the screw 114 can be driven to rotate by the driving output of the rotating motor 117.

[0029] Finally, the protective cover 111 is fixedly connected to the support bracket 107 and is located on the side of the support bracket 107 close to the indicator light 110. The protective cover 111 is adhered to the support bracket 107. The protective cover 111 is made of transparent plastic material. The protective cover 111 can shield and protect the indicator light 110 on the support bracket 107 without affecting the indication function of the indicator light 110.

[0030] When using an automated sampling device for drug absorption and permeation testing according to the present embodiment, when the sample pool 104 is transported by the conveyor belt 103, the trigger block 106 on the positioning block 105 of the sample pool 104 moves to directly below the sensor 109, so that the trigger block 106 triggers the sensor 109 and starts the indicator light 110 to light up and the conveyor belt 103 to stop, so that the position of the sample pool 104 is quickly positioned and moved to the collection position of the workstation 101 for collection, thereby avoiding the need for manual labor to spend a long time to position the sample pool 104 and the collection position of the workstation 101.

[0031] The second embodiment of the present application is:

[0032] Based on the first embodiment, please refer to Figure 5 , Figure 5 It is a structural schematic diagram of an automated sampling device for drug absorption and permeation testing according to the second embodiment of the present invention.

[0033] The utility model provides an automatic sampling device for drug absorption and permeation testing, which further includes a supporting component. The supporting component includes a supporting base 201 and a rotating disk 202 .

[0034] The support base 201 is fixedly connected to the conveying frame 102 and is located on one side of the conveying frame 102; the rotating disk 202 is rotatably connected to the support base 201 and is fixedly connected to the screw 114, and is located on the side of the support base 201 close to the screw 114. There are two support bases 201, and two support bases 201 are welded on the conveying frame 102. There are two rotating disks 202, and the two rotating disks 202 are rotatably connected in the corresponding two support bases 201. The support base 201 is used to realize the connection and support of the rotating disk 202 during rotation. The two screws 114 are welded to the corresponding two rotating disks 202, so that the rotating disk 202 can connect and support the far end of the screw 114 during rotation, thereby making the rotation of the screw 114 more stable.

[0035] The above disclosure is merely one or more preferred embodiments of the present application and is not intended to limit the scope of the present application. A person skilled in the art will understand that all or part of the processes of the above embodiments and equivalent changes made in accordance with the claims of the present application are still within the scope of the present application.

Claims

1. An automated sampling device for drug absorption and permeation testing, comprising a workstation, a conveyor frame, and a conveyor belt, wherein the conveyor frame is arranged on the workstation and is located on one side of the workstation, and the conveyor belt is arranged on the conveyor frame and is located on one side of the conveyor frame, characterized in that: Also includes positioning components, The positioning assembly includes a sample pool, a positioning block, a trigger block, a support bracket, a fixing seat, a sensor, an indicator light and a locking member. The sample pool is arranged on the conveyor belt and is located on one side of the conveyor belt. The positioning block is fixedly connected to the sample pool and is located on one side of the sample pool. The trigger block is arranged and fixedly connected to the positioning block and is located on one side of the positioning block. The support bracket is fixedly connected to the conveyor frame and is located on one side of the conveyor frame. The fixing seat is fixedly connected to the support bracket and is located on one side of the support bracket. The sensor is arranged on the fixing seat and is located on a side of the fixing seat close to the trigger block. The indicator light is arranged on the support bracket and is located on one side of the support bracket. The locking member is arranged on the conveyor frame.

2. The automated sampling device for drug absorption and permeation testing according to claim 1, wherein: The locking component includes a directional rod, a sliding block, a screw, an abutment plate and a rotating component. The directional rod is fixedly connected to the conveying frame and is located on one side of the conveying frame; the sliding block is slidably connected to the directional rod and is located on one side of the directional rod; the screw is connected to the directional rod through the rotating component and is threadedly connected to the sliding block; the abutment plate is fixedly connected to the sliding block and is located on a side of the sliding block close to the sample pool. The rotating component is arranged on the directional rod and connected to the screw.

3. The automated sampling device for drug absorption and permeation testing according to claim 2, wherein: The rotating component includes a mounting seat and a rotating motor. The mounting seat is fixedly connected to the directional rod and is located on one side of the directional rod. The rotating motor is fixedly connected to the mounting seat and connected to the screw rod, and is located on a side of the mounting seat close to the screw rod.

4. The automated sampling device for drug absorption and permeation testing according to claim 1, wherein: The positioning assembly further includes a protective cover, which is fixedly connected to the support bracket and is located on a side of the support bracket close to the indicator light.

5. The automated sampling device for drug absorption and permeation testing according to claim 2, wherein: The locking member also includes a supporting component, which includes a supporting base and a rotating disk. The supporting base is fixedly connected to the conveying frame and is located on one side of the conveying frame; the rotating disk is rotatably connected to the supporting base and fixedly connected to the screw, and is located on a side of the supporting base close to the screw.

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