Device for subpackaging biological samples at low temperature

Abstract

The utility model discloses a low-temperature biological sample sub-packaging device, which belongs to the field of biological sample boxes, a sample test tube is inserted into an end face opening of each modular sub-packaging frame, and the number of the sample test tubes is adjusted by adjusting the number of the modular sub-packaging frames; a concave groove is formed in the inner end of the heat preservation sealing cover, a sealed expansion frame is arranged on the inner edge of the concave groove, a sealed abutting cover is arranged in the sealed expansion frame, a filler bin is formed in the sealed expansion frame and the sealed abutting cover, and the sealed abutting cover abuts against the sample test tube to prevent shaking. The sample storage amount can be flexibly adjusted through the modular split charging frame design. And the anti-skid rubber strips enhance the stability and comfort. The sample test tubes are stably inserted through the equidistant arc design of the insertion holes. The sealing type abutting cover is dynamically adjusted, stable and capable of preventing shaking. The sealing frame and the cover are fastened through bolts, and the rubber strips enhance the sealing effect. A stable structure is ingeniously designed, low-temperature preservation and transportation of biological samples are guaranteed, and huge application potential and value are shown.

Description

Technical Field

[0001] The utility model relates to the field of biological sample boxes, in particular to a low-temperature biological sample packaging device. Background Art

[0002] Cryogenic biological sample dispensing devices, a powerful tool for meticulously dispensing precious biological samples (such as cells, tissues, DNA, and RNA) at extremely low temperatures, integrate advanced refrigeration systems to maintain a low temperature environment throughout the dispensing process, effectively preventing sample degradation and deterioration caused by temperature fluctuations. This device not only precisely controls dispensing volume, minimizing errors, but also significantly reduces the risk of cross-contamination between samples. Furthermore, some high-end models incorporate automated features, significantly improving work efficiency and reducing potential human errors.

[0003] In the daily operations of laboratories and biobanks, low-temperature biological sample packaging devices play a vital role and are key tools to ensure the long-term storage quality of biological samples and the smooth progress of subsequent research.

[0004] However, it's important to note that during sample transportation, insulation and sealing measures must be strictly enforced to ensure sample stability in low-temperature environments. Furthermore, the safety of test tubes must be carefully protected to prevent external contamination and physical damage. Given the potential issues with current cryogenic sample boxes, such as insufficient insulation, loose seals, and inadequate tube securing, we urgently need to continuously optimize product design to improve insulation efficiency and safety, thereby ensuring the safety and stability of biological samples throughout the entire transportation chain. Utility Model Content

[0005] The main purpose of the present invention is to provide a low-temperature biological sample packaging device, which can effectively solve the problems raised in the background technology.

[0006] In order to achieve the above purpose, the technical solution adopted by the utility model is:

[0007] A low-temperature biological sample packaging device comprises a low-temperature packaging box, a hinge device and a heat-insulating sealing cover, wherein the heat-insulating sealing cover is mounted on the low-temperature packaging box via the hinge device and the upper end of the low-temperature packaging box is sealed by the heat-insulating sealing cover;

[0008] The upper end of the low-temperature packaging box is provided with a sealing frame, and the sealing frame and the thermal insulation sealing cover are provided with mounting holes, and bolts are inserted into the mounting holes to achieve locking of the thermal insulation sealing cover and the low-temperature packaging box;

[0009] A limiting fixing frame is provided inside the low-temperature subpackaging box, and an installation compartment is formed inside the limiting fixing frame. A plurality of modular subpackaging racks are installed in the installation compartment. A sample test tube is inserted into an end opening of each modular subpackaging rack. The number of modular subpackaging racks is adjusted to adjust the number of sample test tubes.

[0010] A recessed groove is provided at the inner end of the heat-insulating sealing cover, and a sealed expansion frame is provided at the inner edge of the recessed groove. A sealed tight cover is provided inside the sealed expansion frame. A stuffing bin is formed inside the sealed expansion frame and the sealed tight cover, and the sample tube is supported by the sealed tight cover to prevent shaking.

[0011] In a further preferred embodiment of the present application, the sealing frame is integrally designed with the low-temperature packaging box, and a sealing rubber strip is provided on the surface of the sealing frame, which faces the inner wall of the thermal insulation sealing cover, and a plurality of mounting holes are equidistantly distributed on the sealing frame and the thermal insulation sealing cover;

[0012] In a further preferred embodiment of the present application, the limiting fixing frame is integrally designed with the low-temperature packaging box, and a non-slip rubber strip is provided on the surface of the limiting fixing frame. A blocking groove is formed at the upper end of the limiting fixing frame, and the modular packaging frame is embedded in the blocking groove and prevented from falling by the limiting fixing frame.

[0013] In a further preferred embodiment of the present application, the jacks at the upper end of the modular sub-packaging rack are equidistantly distributed, and the edges of the jacks are arc-shaped. The surface of the modular sub-packaging rack is provided with an anti-slip rubber strip, which presses the modular sub-packaging rack against the low-temperature sub-packaging box;

[0014] In a further preferred embodiment of the present application, the sealed expansion frame and the sealed abutment cover are designed as an integrated whole, and the sealed expansion frame is connected to the heat-insulating sealing cover by an adhesive, and the sealed abutment cover faces the modular sub-assembly rack;

[0015] According to a further preferred embodiment of the present application, sealing filler balls are injected into the filling bin, and the sealing filler balls change the surface area of ​​the sealing tight cover as the filling bin flows.

[0016] Compared with the prior art, the present invention has the following beneficial effects:

[0017] In this utility model, we designed a modular dispensing rack that can flexibly meet different user requirements for the number of sample tubes to be stored, enabling personalized sample storage solutions while improving storage efficiency. To ensure a secure connection between components and user comfort, we added anti-slip rubber strips to the surfaces of the limiter bracket and modular dispensing rack. This design not only enhances friction but also improves the sense of security during use.

[0018] At the top of the modular dispensing rack, we've specially designed equidistantly spaced sockets with curved edges, making the insertion and securement of sample tubes easy and secure. Furthermore, the sealed retaining cover, embedded with sealing balls, dynamically adjusts the retaining force on the sample tubes, effectively preventing sway and ensuring safe and stable sample transport.

[0019] To create a tightly sealed storage environment, the sealing frame and thermal insulation cover feature equally spaced mounting holes, secured with bolts. Furthermore, the use of sealing rubber strips further enhances the device's sealing performance. This sophisticated design and robust structure provide strong support for the cryogenic storage and transportation of biological samples, demonstrating the device's immense potential and value in related fields. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0021] Figure 2 This is a diagram showing the overall structure of the present utility model;

[0022] Figure 3 This is a cross-sectional view of the heat-insulating sealing cover, the sealed expansion frame and the sealed abutting cover of the present invention;

[0023] Figure 4 This is a display diagram of the modular sub-assembly rack and the limiting fixing rack of the present utility model.

[0024] In the figure: 1. Low-temperature packaging box; 2. Sealing frame; 3. Mounting hole; 4. Insulation sealing cover; 5. Hinge device; 6. Recessed groove; 7. Sealed expansion frame; 8. Sealed tight cover; 9. Filling bin; 10. Limiting fixing frame; 11. Mounting bin; 12. Modular packaging rack; 13. Sample tube. DETAILED DESCRIPTION

[0025] In order to make the technical means, creative features, objectives and effects achieved by the present invention easier to understand, the present invention is further described below in conjunction with specific implementation methods.

[0026] like Figure 1 - Figure 4 As shown, this device is an advanced low-temperature biological sample packaging device. Its core components include a low-temperature packaging box 1, a hinge device 5, a heat-insulating sealing cover 4, and a series of carefully designed auxiliary structures. The low-temperature packaging box 1 serves as the foundation of the entire device, and its upper end is cleverly designed with a sealing frame 2. This sealing frame 2 and the low-temperature packaging box 1 are integrated into a design to ensure structural stability and sealing. The surface of the sealing frame 2 is also thoughtfully configured with a sealing rubber strip, which directly faces the inner wall of the heat-insulating sealing cover 4, further enhancing the sealing effect.

[0027] The thermal insulation sealing cover 4 is securely mounted on the low-temperature packaging box 1 via a precise hinge assembly 5, tightly sealing the upper end of the low-temperature packaging box 1. To ensure a secure seal, multiple equally spaced mounting holes 3 are meticulously arranged on both the thermal insulation sealing cover 4 and the sealing frame 2. Bolts are inserted and tightened through these holes to tightly lock the thermal insulation sealing cover 4 and the low-temperature packaging box 1 together.

[0028] The interior space of the cryogenic packaging box 1 is efficiently utilized, with a built-in retaining bracket 10 forming a stable mounting compartment 11. Within this compartment 11, users can flexibly install multiple modular packaging racks 12. These racks are designed with practicality in mind, with end openings accommodating easy insertion of sample tubes 13. Users can flexibly adjust the number of sample tubes 13 by adjusting the number of modular packaging racks 12, achieving personalized and efficient sample storage.

[0029] The inner end of the heat-insulating sealing cover 4 is designed with a recessed groove 6, which cleverly integrates the structure of the sealed expansion frame 7 and the sealed tight cover 8. The sealed expansion frame 7 and the sealed tight cover 8 are designed as an integrated whole and are tightly connected to the heat-insulating sealing cover 4 by adhesive. The sealed tight cover 8 directly faces the modular sub-packaging rack 12 and the sample tubes 13 thereon. Through the dynamic adjustment of the sealing filler balls inside it (these filler balls can flow freely in the filler bin 9), the sample tubes 13 can be firmly pressed and prevented from shaking. This design not only ensures the safety and stability of samples during transportation, but also greatly improves storage efficiency and convenience.

[0030] Furthermore, key components like the position-limiting fixture 10 and the modular dispensing rack 12 are all fitted with anti-slip rubber strips. These not only enhance friction and stability between components, but also improve user comfort and security during use. Furthermore, the jacks at the top of the modular dispensing rack 12 are evenly spaced and feature curved edges. This detail ensures smoother and more secure insertion and secure fixation of the sample tubes 13.

[0031] This low-temperature biological sample packaging device has demonstrated great application potential and value in the field of low-temperature storage and transportation of biological samples with its sophisticated design, stable structure and efficient storage function.

[0032] During Use: Ensure the device is placed on a stable work surface to avoid shaking or tilting. Check that the low-temperature dispensing box 1, insulation sealing cover 4, hinge assembly 5, sealing rubber strip, limit fixing bracket 10, modular dispensing rack 12, and other components are intact. Check that the sealing balls in the packing chamber 9 are sufficient to ensure a good seal.

[0033] Gently lift the heat-insulating sealing cover 4 and completely open the heat-insulating sealing cover 4 through the smooth rotation of the hinge device 5 to expose the inner space of the low-temperature packaging box 1.

[0034] Select an appropriate number of modular sub-packaging racks 12 based on the number of samples to be stored. Guided by the position-limiting fixtures 10, the modular sub-packaging racks 12 are stably placed in the installation chamber 11. Ensure that each sub-packaging rack is securely fixed to the position-limiting fixtures 10 to prevent displacement during subsequent operations.

[0035] Insert the biological sample tubes to be stored one by one into the end openings of the modular dispensing rack 12. Pay attention to adjusting the position of the test tubes so that they are firmly fixed on the dispensing rack to avoid shaking.

[0036] Grab the thermal insulation cover 4 and slowly lower it over the low-temperature dispensing box 1. Observe the contact between the rubber seal and the sealing frame 2 to ensure a tight fit. Align the mounting holes 3 on the thermal insulation cover 4 with the corresponding holes on the sealing frame 2 and insert the bolts to secure. Tighten the bolts to ensure a tight seal between the thermal insulation cover 4 and the low-temperature dispensing box 1.

[0037] Gently shake the low-temperature packaging box 1 to observe whether there is any looseness or air leakage between the thermal insulation sealing cover 4 and the low-temperature packaging box 1. If necessary, further check the condition of the sealing rubber strip and the sealing filler ball and make appropriate adjustments.

[0038] Place the device in a low-temperature environment to store biological samples. During transportation, ensure the device is stable and steady to avoid severe vibration or collision. With its sophisticated design, robust structure, and efficient storage capabilities, this device provides reliable protection for the cryogenic storage and transportation of biological samples.

[0039] This innovative modular dispensing rack allows for flexible adjustment of the number of sample tubes to meet individual user needs, achieving efficient and customized sample storage. Its unique design features anti-slip rubber strips covering both the retaining bracket and the modular dispensing rack. This design not only enhances friction between components, ensuring stability, but also enhances user comfort and security during operation. The evenly spaced insertion holes and curved edges at the top of the modular dispensing rack ensure smooth and secure insertion and securement of sample tubes. The sealed retaining cover, dynamically adjusted by internal sealing balls, securely holds the sample tubes in place and effectively prevents movement, ensuring safe and stable sample transport. Furthermore, the sealing frame and thermally insulated cover are connected by evenly spaced mounting holes and bolts, ensuring a tight seal. The addition of rubber strips further enhances the seal, ensuring even better performance when storing and transporting biological samples at low temperatures.

[0040] The above are preferred embodiments of the present invention and the technical principles used therein. For those skilled in the art, without departing from the spirit and scope of the present invention, any obvious changes such as equivalent transformations, simple replacements, etc. based on the technical solution of the present invention shall fall within the scope of protection of the present invention.

Claims

1. A low-temperature biological sample packaging device, comprising a low-temperature packaging box (1), a hinge device (5) and a heat-insulating sealing cover (4), wherein the heat-insulating sealing cover (4) is mounted on the low-temperature packaging box (1) via the hinge device (5), and the upper end of the low-temperature packaging box (1) is sealed by the heat-insulating sealing cover (4), characterized in that: The upper end of the low-temperature packaging box (1) is provided with a sealing frame (2), and the sealing frame (2) and the heat-insulating sealing cover (4) are both provided with mounting holes (3), and bolts are inserted into the mounting holes (3) to achieve locking of the heat-insulating sealing cover (4) and the low-temperature packaging box (1); The low-temperature sub-packaging box (1) is provided with a limiting fixing frame (10), and the interior of the limiting fixing frame (10) forms an installation chamber (11), and a plurality of modular sub-packaging frames (12) are installed in the installation chamber (11), and a sample test tube (13) is inserted into the end opening of each modular sub-packaging frame (12), and the number of the sample test tubes (13) can be adjusted by adjusting the number of the modular sub-packaging frames (12); The inner end of the heat-insulating sealing cover (4) is provided with a recessed groove (6), and the inner edge of the recessed groove (6) is provided with a sealed expansion frame (7), and a sealed tight cover (8) is provided inside the sealed expansion frame (7). A stuffing bin (9) is formed inside the sealed expansion frame (7) and the sealed tight cover (8), and the sealed tight cover (8) is used to press against the sample tube (13) to prevent shaking.

2. The low-temperature biological sample packaging device according to claim 1, characterized in that: The sealing frame (2) is designed as an integral unit with the low-temperature packaging box (1), and a sealing rubber strip is provided on the surface of the sealing frame (2), which faces the inner wall of the thermal insulation sealing cover (4). A plurality of mounting holes (3) are evenly distributed on the sealing frame (2) and the thermal insulation sealing cover (4).

3. The low-temperature biological sample packaging device according to claim 2, characterized in that: The limiting fixing frame (10) is designed as an integral unit with the low-temperature sub-packaging box (1), and a non-slip rubber strip is provided on the surface of the limiting fixing frame (10). The upper end of the limiting fixing frame (10) forms a blocking groove, and the modular sub-packaging frame (12) is embedded in the blocking groove and prevented from falling by the limiting fixing frame (10).

4. The low-temperature biological sample packaging device according to claim 3, characterized in that: The sockets at the upper end of the modular sub-packaging rack (12) are evenly spaced, and the edges of the sockets are designed to be arc-shaped. The surface of the modular sub-packaging rack (12) is provided with an anti-slip rubber strip, and the modular sub-packaging rack (12) is pressed against the low-temperature sub-packaging box (1) by the anti-slip rubber strip.

5. The low-temperature biological sample packaging device according to claim 4, characterized in that: The sealed expansion frame (7) and the sealed abutting cover (8) are designed as an integral whole, and the sealed expansion frame (7) is connected to the heat-insulating sealing cover (4) via an adhesive, and the sealed abutting cover (8) faces the modular sub-assembly rack (12).

6. The low-temperature biological sample packaging device according to claim 5, characterized in that: Sealing filler balls are injected into the filling bin (9), and the sealing filler balls change the surface area of ​​the sealing tight cover (8) as the filling bin (9) flows.

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