Piercing structure, reagent storage device and sample treatment equipment
By designing the punctured parts and filter parts in the punctured structure, the problem of cross-contamination of samples after the aluminum film in the cassette chamber is punctured, achieving the effect of preventing cross-contamination while relieving pressure.
Patent Information
- Application Number
- CN202421800566.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-29
- Publication Date
- 2025-09-02
- Estimated Expiration
- 2034-07-29
AI Technical Summary
In the prior art, the aluminum film of the chamber of the cartridge is punctured easily leads to cross-contamination between samples, affecting the accuracy of experimental data.
A puncture structure is designed, including a shell, a puncture member and a filter member. The puncture member slides along the first accommodation cavity of the shell, and the puncture member seals and abuts with the inner wall of the shell, and communicates with the outside world through the second accommodation cavity on the puncture member. The filter member is filled in part of the second accommodation cavity to prevent cross-contamination.
After puncture of the aluminum membrane, it is achieved to prevent cross-contamination of samples through the filter element, ensuring the accuracy and safety of experimental data.
Smart Images

Figure CN223291429U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of sample processing, and in particular to a puncture structure, a reagent storage device and a sample processing device. Background Art
[0002] In the field of biological testing, cartridges are commonly used to store reagents and samples. These cartridges consist of multiple chambers, and they utilize the principle of volume displacement to transfer reagents and samples between them for the purpose of biological experiments. During storage and transportation, cartridges must be airtight, and therefore, aluminum foil is sealed around the top of each chamber to prevent leakage. During use, the foil must be opened or punctured to allow the chamber to communicate with the outside world, equalizing internal pressure and facilitating the transfer of reagents or samples.
[0003] Existing puncture structures include a puncture head with a sharp tip. Pressing the puncture head causes the tip to contact and puncture the aluminum membrane. Once the membrane is punctured, the sample inside the chamber is directly exposed to the outside, causing the sample to contaminate the experimental environment, thereby affecting the experimental data of other samples and causing cross-contamination between samples. Utility Model Content
[0004] The purpose of the present utility model is to provide a puncture structure, a reagent storage device and a sample processing device to solve the technical problem in the prior art that the aluminum film of the chamber of the card box is easily punctured and causes cross contamination between samples.
[0005] As conceived above, the technical solution adopted by the utility model is:
[0006] A puncture structure comprising:
[0007] A housing is provided with a first accommodating cavity extending along a first straight line direction;
[0008] a piercing member capable of sliding along the first accommodating cavity, the piercing member being in sealing contact with the inner wall of the first accommodating cavity, one end of the piercing member forming a piercing portion, and the piercing member defining a second accommodating cavity extending along the first straight line;
[0009] A filter element is provided, wherein the filter element is filled in at least a portion of the second accommodating cavity.
[0010] Preferably, the puncturing member includes a supporting portion and a sealing portion, the supporting portion extends along the first straight line, the sealing portion is arranged around the outer circumference of the supporting portion and elastically abuts against the inner wall of the first accommodating cavity, the puncturing portion is arranged at one end of the supporting portion, and the second accommodating cavity passes through the supporting portion and the puncturing portion.
[0011] Preferably, the sealing portion extends spirally around the supporting portion, or the sealing portion is provided with multiple layers along the first straight direction.
[0012] Preferably, the puncturing member further includes a limiting portion, which is arranged on the outer periphery of the supporting portion and located on the side of the sealing portion away from the puncturing portion. A limiting hole is provided on the outer shell, and part of the limiting portion is inserted into the limiting hole. The puncturing member can drive the limiting portion to disengage from the limiting hole during the sliding process.
[0013] Preferably, a guiding slope is provided at one end of the shell away from the puncturing portion, and the guiding slope guides the limiting portion to slide into the limiting hole.
[0014] Preferably, the limiting portion is a flexible member or an elastic member, and after the limiting portion is separated from the limiting hole, it abuts against the inner wall of the shell and undergoes elastic deformation.
[0015] Preferably, the second accommodating chamber is a stepped chamber, and the second accommodating chamber includes a fourth chamber, a fifth chamber, and a sixth chamber that are connected in sequence. The sixth chamber is arranged at the puncture portion, and the filter element is arranged in the fifth chamber.
[0016] A reagent storage device includes a storage body and the puncture structure as described above, wherein the storage body is provided with a storage cavity, the top of the storage cavity is sealed with a sealing film, the shell is provided at the top of the storage cavity and connected to the storage body, and the puncture portion is opposite to the sealing film.
[0017] Preferably, the reagent storage device is a reagent cartridge, and the storage body is provided with at least two storage cavities.
[0018] A sample processing device includes the reagent storage device as described above, and further includes a driving mechanism, wherein the driving mechanism selectively abuts against the piercing member and can drive the piercing member to move along the first linear direction.
[0019] Beneficial effects of the utility model:
[0020] The puncture structure proposed by the present invention is characterized in that a first accommodating chamber extending along a first straight line direction is provided on the outer shell, and the puncture member can slide along the first accommodating chamber. During the sliding process, the puncture portion can puncture the aluminum film. Since the puncture member is in sealing contact with the inner wall of the first accommodating chamber, the aluminum film is connected to the outside through the second accommodating chamber opened on the puncture member after being punctured, thereby achieving the purpose of pressure relief; since the filter element is filled in at least a part of the second accommodating chamber, it plays a filtering role to prevent cross-contamination of the sample through the second accommodating chamber. BRIEF DESCRIPTION OF THE DRAWINGS
[0021] Figure 1is a cross-sectional view of a puncture structure provided by an embodiment of the present utility model;
[0022] Figure 2 is a cross-sectional view of a housing provided by an embodiment of the present utility model;
[0023] Figure 3 is a cross-sectional view of a piercing member provided in an embodiment of the present utility model;
[0024] Figure 4 This is a cross-sectional view of the puncture structure provided by the embodiment of the utility model when in use Figure 1 ;
[0025] Figure 5 This is a cross-sectional view of the puncture structure provided by the embodiment of the utility model when in use Figure 2 ;
[0026] Figure 6 It is a schematic structural diagram of a reagent storage device provided by an embodiment of the present utility model;
[0027] Figure 7 It is a cross-sectional view of a reagent storage device provided in an embodiment of the present utility model.
[0028] In the picture:
[0029] 10. Housing; 11. First accommodating cavity; 111. First cavity; 112. Second cavity; 113. Third cavity; 12. Limiting hole; 13. Guide slope;
[0030] 20. Piercing member; 21. Piercing portion; 22. Second accommodating chamber; 221. Fourth chamber; 222. Fifth chamber; 223. Sixth chamber; 23. Support portion; 24. Sealing portion; 25. Limiting portion; 26. Flanging;
[0031] 30. Filter element;
[0032] 110. Storage body; 101. Storage cavity; 120. Sealing film; 130. Box cover. DETAILED DESCRIPTION
[0033] The following describes in detail embodiments of the present invention. Examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to explain the present invention, and should not be construed as limiting the present invention.
[0034] In the description of this utility model, unless otherwise specified or limited, the terms "connected," "connect," and "fixed" should be understood in a broad sense. For example, they can refer to fixed connection, detachable connection, or integration; mechanical connection or electrical connection; direct connection or indirect connection through an intermediate medium; internal communication between two components or interaction between two components. Those skilled in the art will understand the specific meanings of the above terms in this utility model based on the specific circumstances.
[0035] In the present invention, unless otherwise expressly specified or limited, a first feature being "above" or "below" a second feature may include the first and second features being in direct contact, or may include the first and second features being in contact not directly but through another feature between them. Moreover, a first feature being "above," "above," and "above" a second feature may include the first feature being directly above or obliquely above the second feature, or may simply mean that the first feature is higher in level than the second feature. A first feature being "below," "below," and "below" a second feature may include the first feature being directly below or obliquely below the second feature, or may simply mean that the first feature is lower in level than the second feature.
[0036] The technical solution of the present invention will be further described below with reference to the accompanying drawings and through specific implementation methods.
[0037] See also Figures 1 to 7 This embodiment provides a puncture structure for puncturing thin films such as aluminum films or plastic films on bottles, boxes or other structures.
[0038] The puncturing structure includes a shell 10, a puncturing member 20 and a filter member 30. The shell 10 is provided with a first accommodating chamber 11 that passes through along a first straight line direction. The puncturing member 20 can slide along the first accommodating chamber 11. The puncturing member 20 is sealed and abutted against the inner wall of the first accommodating chamber 11. One end of the puncturing member 20 forms a puncturing portion 21. The puncturing member 20 is provided with a second accommodating chamber 22 that passes through along the first straight line direction; the filter member 30 fills at least a portion of the second accommodating chamber 22.
[0039] The first accommodating chamber 11 provided on the housing 10 is used to accommodate the puncturing member 20. The puncturing member 20 can slide along the first accommodating chamber 11. During the sliding process, the puncturing portion 21 can puncture the aluminum film. Since the puncturing member 20 is in sealed contact with the inner wall of the first accommodating chamber 11, the second accommodating chamber 22 opened on the puncturing member 20 is connected to the outside world to achieve the purpose of pressure relief; since the filter element 30 is filled in at least a part of the second accommodating chamber 22, it plays a filtering role to prevent cross-contamination of the sample through the second accommodating chamber 22.
[0040] The first accommodating chamber 11 provides an accommodating space for the piercing member 20 and allows the piercing member 20 to slide therein. Along the first straight line direction, a portion of the inner wall of the first accommodating chamber 11 is in sealing contact with the piercing member 20 to achieve sealing.
[0041] The piercing member 20 includes a support portion 23 and a sealing portion 24. The support portion 23 extends along a first straight line. The sealing portion 24 is disposed around the outer periphery of the support portion 23 and elastically abuts against the inner wall of the first accommodating chamber 11. The piercing portion 21 is disposed at one end of the support portion 23. The second accommodating chamber 22 extends through the support portion 23 and the piercing portion 21. The second accommodating chamber 22 extends through the support portion 23 and the piercing portion 21 along the first straight line. Typically, the first accommodating chamber 11 has a circular cross-section, so the support portion 23 can be cylindrical. In other embodiments, the support portion 23 can also be rectangular, as long as it can adapt to the first accommodating chamber 11.
[0042] In some embodiments, the outer circumferential surface of the puncture portion 21 is conical and has a pointed end to facilitate puncturing the sealing membrane 120. In some embodiments, the puncture portion 21 includes at least three puncture plates evenly arranged around the circumference, and the puncture plates can be triangular to facilitate puncturing the sealing membrane 120.
[0043] Alternatively, the sealing portion 24 may be spirally extended around the support portion 23 to increase the sealing area and improve the sealing effect. Alternatively, the sealing portion 24 may be provided with multiple layers along the first straight line direction to increase the sealing area and improve the sealing effect.
[0044] The support portion 23 and the sealing portion 24 can be integrally formed to reduce the number of parts. For example, the support portion 23 can be made of plastic, and the sealing portion 24 can be a thin plastic sheet. Alternatively, the support portion 23 and the sealing portion 24 can be detachably connected. For example, the outer surface of the support portion 23 can be provided with a groove, and the sealing portion 24 can be a rubber ring partially inserted into the groove.
[0045] The piercing member 20 further includes a stopper 25, which is disposed on the outer periphery of the support portion 23 and on the side of the sealing portion 24 away from the piercing portion 21. The housing 10 defines a stopper hole 12, into which a portion of the stopper 25 is inserted. During sliding, the piercing member 20 can drive the stopper 25 out of the stopper hole 12. Before the piercing member 20 slides, the stopper 25 is located within the stopper hole 12, limiting the position of the piercing member 20. When the piercing member 20 is pressed, it slides along the first accommodating cavity 11, driving the stopper 25 out of the stopper hole 12.
[0046] The limiting portion 25 is a flexible or elastic member. After the limiting portion 25 is released from the limiting hole 12, it abuts against the inner wall of the housing 10 and elastically deforms. The limiting portion 25 itself has a certain degree of elasticity. For example, the limiting portion 25 is made of soft plastic. After the limiting portion 25 is released from the limiting hole 12, the limiting portion 25 abuts against the inner wall of the housing 10 and elastically deforms. Therefore, as the piercing member 20 continues to slide, the limiting portion 25 remains in contact with the inner wall of the housing 10, thereby limiting the piercing member 20 to a certain extent.
[0047] Part of the first accommodating chamber 11 is used to accommodate the sealing portion 24, and part of the first accommodating chamber 11 is used to accommodate the limiting portion 25. The first accommodating chamber 11 can be a stepped chamber. In some embodiments, the first accommodating chamber 11 includes a first chamber 111 and a second chamber 112 that are connected in sequence, the limiting portion 25 is arranged in the first chamber 111, and the sealing portion 24 is arranged in the second chamber 112. The cross-sectional area of the first chamber 111 is larger than the cross-sectional area of the second chamber 112, which facilitates the accommodation of the limiting portion 25. The limiting hole 12 is connected to the first chamber 111. In some embodiments, the first accommodating chamber 11 includes a first chamber 111, a second chamber 112, and a third chamber 113 that are connected in sequence, the limiting portion 25 is arranged in the first chamber 111, the sealing portion 24 is arranged in the second chamber 112, and the cross-sectional area of the third chamber 113 is larger than the cross-sectional area of the second chamber 112. By providing the third chamber 113, it is convenient to install the housing 10 on other structures.
[0048] The support portion 23 may be stepped. A flange 26 is provided at one end of the support portion 23 away from the puncture portion 21. The flange 26 extends circumferentially around the support portion 23. The flange 26 increases the end area of the support portion 23, making it easier to press the support portion 23.
[0049] The end of the housing 10 away from the piercing portion 21 is provided with a guide slope 13, which guides the limiting portion 25 into the limiting hole 12. During installation, the piercing member 20 is inserted into the first accommodating cavity 11, the limiting portion 25 is aligned with the position of the limiting hole 12, and the piercing member 20 is pressed into the first accommodating cavity 11, causing the limiting portion 25 to slide along the guide slope 13 into the limiting hole 12.
[0050] In this embodiment, the limiting portion 25 includes two limiting rods, which are distributed on both sides of the support portion 23 , and each limiting rod is provided with a limiting hole 12 . The guiding slope 13 is located on one side of the limiting hole 12 .
[0051] The second accommodating chamber 22 can be a stepped chamber to facilitate installation of the filter element 30 and to facilitate positioning of the filter element 30. Alternatively, the second accommodating chamber 22 includes a fourth chamber 221, a fifth chamber 222, and a sixth chamber 223 that are sequentially connected. The sixth chamber 223 is disposed at the puncture portion 21, and the filter element 30 is disposed within the fifth chamber 222. The cross-sectional areas of the fourth chamber 221, the fifth chamber 222, and the sixth chamber 223 decrease sequentially, facilitating installation of the filter element 30 from the fourth chamber 221 to the fifth chamber 222 and facilitating positioning of the filter element 30 by the step between the fifth chamber 222 and the sixth chamber 223.
[0052] One or more filter elements 30 may be provided. Multiple filter elements 30 may be spaced apart along the first straight line within the second accommodating chamber 22. The filter element 30 may be made of existing PP cotton, activated carbon, or resin, or may be a PE sintered element.
[0053] This embodiment also provides a reagent storage device, including a storage body 110 and the above-mentioned puncture structure, wherein a storage cavity 101 is provided on the storage body 110, and a sealing film 120 is provided on the top of the storage cavity 101. The outer shell 10 is provided on the top of the storage cavity 101 and is connected to the storage body 110, and the puncture portion 21 is opposite to the sealing film 120.
[0054] During use, by pressing the piercing member 20, the piercing member 20 can be driven to slide along the first accommodating chamber 11. During the sliding process, the piercing portion 21 pierces the sealing membrane 120. Since the piercing member 20 is in sealing contact with the inner wall of the first accommodating chamber 11, after the sealing membrane 120 is pierced, the storage body 110 is connected to the outside through the second accommodating chamber 22 opened on the piercing member 20, thereby achieving the purpose of pressure relief; since the filter element 30 is filled in at least a part of the second accommodating chamber 22, it plays a filtering role to prevent cross-contamination of the sample through the second accommodating chamber 22.
[0055] In this embodiment, the storage body 110 is provided with a mounting groove that is annularly arranged around the circumference of the storage cavity 101. The housing 10 is sleeved onto the storage body 110 and inserted into the mounting groove. The housing 10 and the storage body 110 can be connected by utilizing their own elasticity or by threaded connection.
[0056] The reagent storage device may be a reagent tube or a reagent bottle. In this embodiment, the reagent storage device is a reagent cartridge, and the storage body 110 is provided with at least two storage cavities 101 .
[0057] The reagent cartridge has a split structure, including not only a storage body 110 but also a box cover 130. The box cover 130 is buckled onto the storage body 110 and covers part of the puncture structure. The end of the puncture member 20 away from the puncture portion 21 is exposed from the box cover 130 for easy pressing.
[0058] In some embodiments, the piercing member 20 is pressed by manual operation. In some embodiments, the piercing member 20 is pressed by an electric mechanism.
[0059] This embodiment further provides a sample processing device comprising the above-described reagent storage device and a drive mechanism, which selectively engages with the piercing member 20 and is capable of driving the piercing member 20 to move along a first linear direction. When the reagent storage device moves to a set position, the drive mechanism engages with the piercing member 20 and drives the piercing member 20 to move along the first linear direction, causing the piercing portion 21 to pierce the sealing membrane 120.
[0060] The above embodiments merely illustrate the basic principles and features of the present invention. The present invention is not limited to the above embodiments. Various changes and modifications are possible without departing from the spirit and scope of the present invention. Such changes and modifications are within the scope of the present invention. The scope of protection claimed in the present invention is defined by the appended claims and their equivalents.
Claims
1. A puncture structure, characterized in that: include: A housing (10), wherein the housing (10) is provided with a first accommodating cavity (11) extending along a first straight line direction; A piercing member (20) is capable of sliding along the first accommodating cavity (11), the piercing member (20) is in sealing contact with the inner wall of the first accommodating cavity (11), one end of the piercing member (20) forms a piercing portion (21), and the piercing member (20) is provided with a second accommodating cavity (22) extending along the first straight line direction; A filter element (30), wherein the filter element (30) is filled in at least a portion of the second accommodating cavity (22).
2. The puncture structure according to claim 1, characterized in that: The piercing member (20) comprises a supporting portion (23) and a sealing portion (24), wherein the supporting portion (23) extends along the first straight line, the sealing portion (24) is arranged around the outer periphery of the supporting portion (23) and elastically abuts against the inner wall of the first accommodating cavity (11), the piercing portion (21) is arranged at one end of the supporting portion (23), and the second accommodating cavity (22) passes through the supporting portion (23) and the piercing portion (21).
3. The puncture structure according to claim 2, characterized in that: The sealing portion (24) extends in a spiral shape around the supporting portion (23), or the sealing portion (24) is provided with multiple layers along the first straight direction.
4. The puncture structure according to claim 2, characterized in that: The piercing member (20) further comprises a limiting portion (25), the limiting portion (25) being arranged on the outer periphery of the supporting portion (23) and being located on a side of the sealing portion (24) away from the piercing portion (21); a limiting hole (12) being provided on the housing (10), a portion of the limiting portion (25) being inserted into the limiting hole (12), and the piercing member (20) being able to drive the limiting portion (25) to disengage from the limiting hole (12) during the sliding process.
5. The puncture structure according to claim 4, characterized in that: A guiding slope (13) is provided at one end of the housing (10) away from the puncturing portion (21), and the guiding slope (13) guides the limiting portion (25) to slide into the limiting hole (12).
6. The puncture structure according to claim 4, characterized in that: The limiting portion (25) is a flexible member or an elastic member. After the limiting portion (25) is separated from the limiting hole (12), it abuts against the inner wall of the housing (10) and undergoes elastic deformation.
7. The puncture structure according to claim 1, characterized in that The second accommodating chamber (22) is a stepped chamber, and the second accommodating chamber (22) includes a fourth chamber (221), a fifth chamber (222), and a sixth chamber (223) that are connected in sequence. The sixth chamber (223) is arranged at the puncturing portion (21), and the filter element (30) is arranged in the fifth chamber (222).
8. A reagent storage device, characterized in that: The invention comprises a storage body (110) and the puncture structure according to any one of claims 1 to 7, wherein a storage cavity (101) is provided on the storage body (110), a sealing film (120) is provided on the top of the storage cavity (101), the housing (10) is provided on the top of the storage cavity (101) and is connected to the storage body (110), and the puncture portion (21) is opposite to the sealing film (120).
9. The reagent storage device according to claim 8, characterized in that: The reagent storage device is a reagent cartridge, and the storage body (110) is provided with at least two storage cavities (101).
10. A sample processing device, characterized in that: The reagent storage device according to claim 8 or 9 further comprises a driving mechanism, wherein the driving mechanism selectively abuts against the piercing member (20) and is capable of driving the piercing member (20) to move along the first straight line direction.