Experimental animal operation support for protecting animal eyes

By designing a surgical tray for experimental animals, which includes an eye cavity and a multi-part support structure, the problem of protecting the non-surgical eyes of experimental animals is solved, and the safety of surgery and the reliability of experimental results are improved.

CN223299201UActive Publication Date: 2025-09-05WUXI APPTEC SUZHOU
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Patent Information

Application Number
CN202421925456.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-08-09
Publication Date
2025-09-05
Estimated Expiration
2034-08-09

AI Technical Summary

Technical Problem

During ophthalmic surgery on experimental animals, the non-surgical eye is susceptible to squeezing or abrasion, which affects the accuracy of surgical results and increases the risk of animal discomfort, and there is a lack of effective protective measures.

Method used

A surgical support for experimental animals is designed, which includes a platform and a main body groove. The main body groove is provided with an eye cavity that matches the corresponding position of the non-surgical eye. It is equipped with nose, forelimb, back, hindlimb and tail cavities to provide stable support. The hand support is used for surgical operations. The materials can be selected from silicone, rubber, etc., and a sterile film can be applied to the surface.

Benefits of technology

Effectively protect non-surgical eyes, reduce extrusion and wear, improve surgical safety and reliability, reduce external interference, and enhance the scientific value of experimental results.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to an experimental animal operation support for protecting the eyes of an animal. The experimental animal operation support comprises a platform and a main body groove formed in the platform. The main body groove is provided with a cavity for accommodating the head of an experimental animal; the main body groove comprises an eye cavity, and the position of the eye cavity is matched with the position of the eye on the corresponding side when the head of the experimental animal is contained in the cavity. According to the utility model, non-surgical eyes of experimental animals are effectively protected, the eyes are prevented from being extruded or abraded, external interference factors which have negative effects on experimental results are reduced, and a safer and more stable operation environment is provided for ophthalmologic operations of the experimental animals, so that the scientific value and reliability of biological experiments and medical research are improved.
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Description

Technical Field

[0001] The utility model relates to the field of biological surgical auxiliary instruments for experimental animals, in particular to an experimental animal surgical support for protecting animal eyes. Background Art

[0002] In laboratory ophthalmology research, rodents, such as mice, rats, and rabbits, differ significantly from humans and non-human primates due to the unique placement of their eyes. These animals have eyes on the sides of their faces, rather than directly in front like humans or non-human primates. This anatomical feature has important implications for the study of eye diseases and their treatment.

[0003] When performing ocular injection surgeries on these experimental animals, such as intravitreal or subretinal injections, it is usually necessary to perform both eye injections on the same animal. However, during surgery, the non-operated eye, or the contralateral eye to the operated eye, may come into contact with the operating table, which can cause corneal abrasion or extrusion, especially if the eye has just been injected, as the risk of drug squeezing out is greatly increased.

[0004] Until now, there has been a lack of standardized protective measures during ophthalmic surgery on experimental animals to ensure that the non-operated eye is not subjected to unnecessary impact and damage. This deficiency may not only affect the accuracy and reliability of surgical results, but also increase the discomfort and risk of postoperative complications for the experimental animals. Utility Model Content

[0005] In view of the above-mentioned defects of the prior art, the present invention provides an experimental animal surgical tray for protecting the eyes of animals, which includes a platform and a main body groove arranged in the platform; the main body groove has a cavity for accommodating the head of the experimental animal; the main body groove includes an eye cavity, and the position of the eye cavity matches the position of the corresponding eye on one side when the head of the experimental animal is accommodated in the cavity.

[0006] In the experimental animal surgical tray as described above, optionally, the number of the main body grooves is 2, and they are arranged in a mirror-symmetrical manner.

[0007] In the aforementioned surgical tray for experimental animals, optionally, the depth of the eye cavity is greater than the depth of other parts of the main body groove.

[0008] In the aforementioned experimental animal surgical tray, optionally, the experimental animal is one or more of a mouse, a rat, and a rabbit.

[0009] In the aforementioned experimental animal surgical tray, optionally, the eye cavity is circular, oval or rectangular, and the diameter or length of the eye cavity is 1.5-3 times the diameter of the eyeball of the experimental animal.

[0010] In the aforementioned experimental animal surgical tray, optionally, the eye cavity is a through-hole structure.

[0011] In the experimental animal surgical tray as described above, optionally, the main body groove further includes a nose and snout cavity, the position of which matches the positions of the mouth and nose corresponding to when the head of the experimental animal is accommodated in the cavity.

[0012] In the experimental animal surgical support as described above, optionally, the main body groove also includes a forelimb chamber and / or a back chamber and / or a hindlimb chamber and / or a tail chamber; the position of the forelimb chamber matches the position of the animal's forelimbs when the head of the experimental animal is accommodated in the cavity, the position of the back chamber matches the position of the animal's back when the head of the experimental animal is accommodated in the cavity, the position of the hindlimb chamber matches the position of the animal's hindlimbs when the head of the experimental animal is accommodated in the cavity, and the position of the tail chamber matches the position of the animal's tail when the head of the experimental animal is accommodated in the cavity.

[0013] In the experimental animal surgical support as described above, optionally, a hand rest is further included; the hand rest is connected to the platform and is closer to the snout cavity than to the eye cavity.

[0014] In the experimental animal surgical support as described above, optionally, the upper surface of the hand support has an arc design.

[0015] In order to promote the quality and ethical standards of ophthalmic research on experimental animals, the utility model proposes an experimental animal surgical support for protecting the animal's eyes, so as to effectively protect the non-surgical eye of the experimental animal, prevent the eye from being squeezed or abraded, reduce external interference factors that have a negative impact on the experimental results, and provide a safer and more stable operating environment for ophthalmic surgery on experimental animals, thereby enhancing the scientific value and reliability of biological experiments and medical research.

[0016] The concept, specific structure and technical effects of the present invention will be further described below in conjunction with the accompanying drawings to fully understand the purpose, characteristics and effects of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 This is a schematic structural diagram of an embodiment of a surgical tray for experimental animals for protecting animal eyes;

[0018] Figure 2This is a schematic structural diagram of another embodiment of an experimental animal surgical support;

[0019] Figure 3 This is a schematic diagram of the structure of an experimental animal surgical tray suitable for mice;

[0020] Figure 4 This is a schematic diagram of the structure of an experimental animal surgical tray suitable for rats;

[0021] Figure 5 This is a schematic diagram of the structure of an experimental animal surgical tray suitable for rabbits.

[0022] Figure markings: 1-platform; 2-main body groove; 21-nose cavity; 22-forelimb cavity; 23-back cavity; 24-hind limb cavity; 25-tail cavity; 3-eye cavity; 4-hand rest. DETAILED DESCRIPTION

[0023] In order to make the technical means, creative features, objectives and effects of the present invention easier to understand, the present invention is further described below with reference to specific figures. However, the present invention is not limited to the following implementation examples.

[0024] It should be noted that the structures, proportions, sizes, etc. illustrated in the drawings in this specification are only used to match the contents disclosed in the specification so that people familiar with this technology can understand and read them. They are not used to limit the conditions under which the present invention can be implemented. Therefore, they have no substantive technical significance. Any structural modifications, changes in proportional relationships, or adjustments in size should still fall within the scope of the technical contents disclosed in this utility model without affecting the effects and purposes that can be achieved by the present utility model.

[0025] Figure 1 The present invention is a schematic structural diagram of an embodiment of a surgical tray for experimental animals for protecting the eyes.

[0026] from Figure 1 As can be seen from the figure, the experimental animal surgical support for protecting the animal's eyes may include a platform 1 and a main body groove 2 ( Figures 1 to 5 The surfaces of all platforms 1 and the main recess 2 are indicated by slanted lines in different directions, indicating that they are located on different planes, with the main recess 2 being lower than the platforms 1. In this embodiment, the main recess 2 is a three-dimensional recessed cavity that can accommodate at least the head of an experimental animal. An eye chamber 3 is also defined within the main recess 2. The position of the eye chamber 3 matches the position of the non-operative eye within the three-dimensional recessed cavity when the head of the experimental animal is accommodated.

[0027] It should be noted that the depth of the eye cavity 3 is greater than the depth of other parts of the main body groove 2. Optionally, the eye cavity 3 can be a directly hollowed-out through-hole structure to save the step of measuring the specific digging depth.

[0028] In an optional embodiment, the eye cavity 3 can be circular, oval, or rectangular, and the diameter or length of the eye cavity 3 is 1.5-3 times the diameter of the experimental animal's eye. Specifically, the experimental animals of the present disclosure can include, but are not limited to, one or more of mice, rats, and rabbits. The diameter of the mouse eyeball is 2.5-4 mm, the diameter of the rat eyeball is 5-7.5 mm, and the diameter of the rabbit eyeball is 15-18 mm.

[0029] Although the groove of the eye chamber 3 can accommodate the eyeball so that it is not squeezed, the surgical operator may not be able to place the experimental animal so accurately. Therefore, the groove of the eye chamber 3 designed in the present invention is larger than the diameter of the eyeball of the experimental animal, which has a certain tolerance.

[0030] In an optional embodiment, if Figure 1 As shown, the main body groove 2 may further include a nose and snout cavity 21, the position of which matches the position of the mouth and nose when the head of the experimental animal is accommodated in the cavity.

[0031] Optionally, the nose and mouth chamber 21 may leave a gap of about 3-6 mm between the nose and mouth of the experimental animal to facilitate the breathing of the experimental animal. Figure 5 The dotted line portion shown in the figure depicts the edge of the nose and snout of the experimental animal lying on its side in the main body groove 2, and the edge of the nose and snout cavity 21 has a certain gap from the dotted line for the animal to breathe.

[0032] For experimental animals of different sizes or weights, not only the size of the depression of the main groove 2 for supporting the body or head is different. In an optional embodiment, the main groove 2 may also include one or more of the forelimb chamber 22 and / or the back chamber 23 and / or the hindlimb chamber 24 and / or the tail chamber 25 to stably support the experimental animal, which can be specifically set according to the actual experimental animal or operation needs. Specifically, the position of the forelimb chamber 22 matches the position of the animal's forelimb when the head of the experimental animal is accommodated in the cavity. The position of the back chamber 23 matches the position of the animal's back when the head of the experimental animal is accommodated in the cavity. The position of the hindlimb chamber 24 matches the position of the animal's hindlimb when the head of the experimental animal is accommodated in the cavity. The position of the tail chamber 25 matches the position of the animal's tail when the head of the experimental animal is accommodated in the cavity.

[0033] like Figures 3 to 5As shown, specifically, under the premise that the main body groove 2 is provided with the above-mentioned eye cavity 3 and can at least accommodate the head of the experimental animal, such as a mouse with a small body size, Figure 3 The main body groove 2 shown in the figure may include a nose cavity 21, a forelimb cavity 22, a back cavity 23, a hindlimb cavity 24, and a tail cavity 25, so that the experimental mouse can be fixed in all directions. For example, the body size of rats is large, and in order to save the cost of the experimental animal surgical support, the main body groove 2 can be as follows Figure 4 As shown, only the nose cavity 21 and the forelimb cavity 22 are provided. Similarly, for a rabbit of a larger size, the main body groove 2 can be as Figure 5 As shown, only the snout cavity 21 is provided. Of course, if cost and occupied area are not taken into consideration, the surgical support for experimental animals such as rats or rabbits can also be made into a main body groove 2 including the snout cavity 21, the forelimb cavity 22, the back cavity 23, the hindlimb cavity 24, and the tail cavity 25 to support the entire body of the experimental animal such as a rat or rabbit.

[0034] In an optional embodiment, the experimental animal surgical support may further include a hand rest 4 for supporting the hands of the surgical operator. The hand rest 4 is connected to the platform 1 and extends to both sides of the top of the experimental animal's head. The hand rest 4 is closer to the nose and snout cavity 21 than to the eye cavity 3. The surgical operator can place both hands or wrists on the hand rest 4 to perform surgery on the experimental animal. In other optional embodiments, the upper surface of the hand rest 4 may also have an arc design, such as a depression similar to a neck pillow, to relieve hand fatigue. It should be noted that the hand rest 4 can be detachably mounted on the platform 1, or it can be directly integrated with the platform 1.

[0035] The experimental animal surgical trays come in pairs, one set is used to protect the animal's left eye, and the other set is used to protect the animal's right eye. Figure 1 The situation shown is one of a pair of experimental animal surgical trays. Figure 1 The experimental animal in the experiment is lying on the right side. At this time, the left eye is the surgical eye, and the surgical tray is protecting the right non-surgical eye of the experimental animal. In actual operation, another surgical tray is used for the right surgical eye of the experimental animal. Figure 1 The experimental animal surgical tray shown is operated with a chiral mirror-symmetrical surgical tray to protect the left non-operated eye.

[0036] In addition to using two independent experimental animal surgical trays to complete the surgery on both sides of the experimental animal's eyeballs, two main body grooves 2 can also be directly set on one experimental surgical tray to accommodate experimental animals in different side-lying directions, respectively. Figure 2 The embodiment shown.

[0037] Figure 2It is a structural schematic diagram of another embodiment of an experimental animal surgical support.

[0038] In order to enable the operator to directly use a laboratory animal surgical tray to perform surgery on both eyes of the experimental animal, Figure 2 The figure shows a case where two main grooves 2 are provided in the above-mentioned experimental animal surgical support. In this embodiment, the platform 1 of the experimental animal surgical support can include a pair of the above-mentioned main grooves 2 arranged in mirror symmetry, corresponding to the different side-lying directions of the experimental animal when undergoing surgery on both eyes. It should be noted that Figure 2 The figure shows only the situation of the main body groove 2 covering the entire body of a mouse as an example.

[0039] The above-mentioned experimental animal surgical support disclosed herein can be made of a material with moderate hardness and easy to clean and disinfect, such as silicone, rubber, acrylic glass, etc. Before the experiment begins, a layer of sterile film can also be applied to the surface of the surgical support for easy replacement.

[0040] The above describes in detail the preferred embodiments of the present invention. It should be understood that numerous modifications and variations based on the concepts of the present invention can be made by those skilled in the art without inventive effort. Therefore, any technical solution that can be derived by a person skilled in the art based on the concepts of the present invention through logical analysis, reasoning, or limited experimentation based on the existing technology shall be within the scope of protection defined by the claims.

Claims

1. A surgical tray for experimental animals for protecting the eyes of animals, characterized in that: The invention comprises a platform (1) and a main body groove (2) arranged in the platform (1); the main body groove (2) has a cavity for accommodating the head of the experimental animal; the main body groove (2) includes an eye cavity (3), and the position of the eye cavity (3) matches the position of one eye corresponding to the head of the experimental animal when the cavity accommodates the eye; the platform (1) is made of silicone material, and a sterile film is applied to the surface of the surgical support before the experiment begins.

2. The experimental animal surgical support according to claim 1, characterized in that: The number of the main body grooves (2) is 2, and they are arranged in a mirror-symmetrical manner.

3. The experimental animal surgical support according to claim 1 or 2, characterized in that: The depth of the eye cavity (3) is greater than the depth of other parts of the main body groove (2).

4. The experimental animal surgical support according to claim 3, characterized in that: The experimental animals are one or more of mice, rats and rabbits.

5. The experimental animal surgical support according to claim 4, characterized in that: The eye cavity (3) is circular, elliptical or rectangular, and the diameter or length of the eye cavity (3) is 1.5-3 times the diameter of the eyeball of the experimental animal.

6. The experimental animal surgical support according to claim 3, characterized in that: The eye cavity (3) is a through-hole structure.

7. The experimental animal surgical support according to claim 1 or 2, characterized in that: The main body groove (2) further comprises a nose-mouth cavity (21), the position of which matches the position of the mouth and nose when the head of the experimental animal is accommodated in the cavity.

8. The experimental animal surgical tray according to claim 7, characterized in that: The main body groove (2) further includes a forelimb cavity (22) and / or a back cavity (23) and / or a hindlimb cavity (24) and / or a tail cavity (25); the position of the forelimb cavity (22) matches the position of the animal's forelimbs when the head of the experimental animal is accommodated in the cavity, the position of the back cavity (23) matches the position of the animal's back when the head of the experimental animal is accommodated in the cavity, the position of the hindlimb cavity (24) matches the position of the animal's hindlimbs when the head of the experimental animal is accommodated in the cavity, and the position of the tail cavity (25) matches the position of the animal's tail when the head of the experimental animal is accommodated in the cavity.

9. The experimental animal surgical tray according to claim 7, characterized in that: It also includes a hand rest (4); the hand rest (4) is connected to the platform (1) and is closer to the nose cavity (21) than to the eye cavity (3).

10. The experimental animal surgical tray according to claim 9, characterized in that: The upper surface of the hand rest (4) has an arc design.