Serum collector for vaccine production

Abstract

The utility model provides a serum collector for vaccine production. The serum collector comprises a collection chamber, a first control valve, a second control valve and a third control valve, a filter membrane is arranged in the collection chamber and divides an inner cavity of the collection chamber into a blood cavity and a serum cavity which are sequentially distributed from top to bottom; the first control valve is connected with the outlet end of the blood inlet pipe, the outlet end of the steam inlet pipe, the outlet end of the liquid supplementing pipe and the inlet end of the main inlet pipe, and the outlet end of the main inlet pipe is communicated with the blood cavity; the second control valve is connected with the outlet end of the first discharge pipe and the inlet end of the second discharge pipe, the inlet end of the first discharge pipe is connected with the blood cavity, and the outlet end of the second discharge pipe is connected with the blood transfusion device; the third control valve is connected with the outlet end of the third discharge pipe and the inlet end of the fourth discharge pipe; the inlet end of the third discharge pipe is connected with the serum cavity. According to the utility model, the consumption of animals in the serum extraction process can be effectively reduced, the vaccine production cost is reduced, the comprehensive disinfection can be realized, and the serum and the collected animals are prevented from being polluted.

Description

Technical Field

[0001] The utility model belongs to the technical field of vaccine production, and particularly relates to a serum collector for vaccine production. Background Art

[0002] Animal serum is an important raw material for vaccine production. To obtain animal serum, animal plasma must first be collected and then separated. To reduce the suffering of animals when obtaining animal plasma, existing procedures generally require sacrificing the animals before obtaining the plasma. This results in a high number of animals used in the serum extraction process, making it difficult to further reduce vaccine production costs. Furthermore, existing serum separation and collection equipment is complex in structure, with many blind spots for cleaning, and often requires disinfection with disinfectants, which can easily breed bacteria, affecting the cleanliness of the extracted serum and subsequent production processes. Utility Model Content

[0003] The embodiment of the present utility model provides a serum collector for vaccine production, which aims to solve the problems in the prior art that in order to meet production needs, animal plasma extraction operations require the consumption of a large number of animals and the equipment is difficult to clean.

[0004] In order to achieve the above purpose, the technical solution adopted by the utility model is:

[0005] Provided is a serum collector for vaccine production, comprising:

[0006] A collection chamber, wherein a filter membrane is provided inside the collection chamber, the filter membrane divides the inner cavity of the collection chamber into a blood cavity and a serum cavity sequentially distributed from top to bottom, and the filter membrane is used to filter the serum;

[0007] a first control valve, connecting the outlet end of the blood inlet tube, the outlet end of the steam inlet tube, the outlet end of the infusion tube, and the inlet end of the main inlet tube, wherein the outlet end of the main inlet tube is connected to the blood chamber;

[0008] a second control valve connected to the outlet end of the first discharge pipe and the inlet end of the second discharge pipe, wherein the inlet end of the first discharge pipe is connected to the blood chamber and the outlet end of the second discharge pipe is connected to the blood transfusion device; and

[0009] The third control valve is connected to the outlet end of the third discharge tube and the inlet end of the fourth discharge tube, and the inlet end of the third discharge tube is connected to the serum chamber.

[0010] In a possible implementation, the serum collector for vaccine production further includes a second downpipe, and the second control valve is connected to an inlet end of the second downpipe.

[0011] In a possible implementation, the serum collector for vaccine production further includes a third lower discharge pipe, and the third control valve is connected to an inlet end of the third lower discharge pipe.

[0012] In a possible implementation, a booster pumping device is provided at the blood inlet tube.

[0013] In some embodiments, a pressure sensor is further provided in the blood chamber, and the booster pumping device is communicatively connected to the pressure sensor.

[0014] In some embodiments, the collection chamber includes a collection box with an opening on the top, and also includes an openable and closable sealing cover provided on the top opening of the collection box; the filter membrane is provided in the middle of the collection box, and the pressure sensor is provided above the filter membrane and connected to the inner wall of the collection box.

[0015] In some embodiments, the sealing cover includes a sealing top plate and a sealing enclosure surrounding the sealing top plate. The sealing enclosure is vertically arranged to the sealing top plate. The sealing enclosure on one side is rotatably connected to the top edge of the collection box, and the sealing enclosure on the other side is clamped to the corresponding side of the top of the collection box through a snap assembly, so that the sealing edge of the sealing enclosure is in close contact with the top surface of the collection box.

[0016] In some embodiments, the filter membrane is detachably connected to the collection box.

[0017] In some embodiments, a frame is connected to the periphery of the filter membrane, and the frame is detachably connected to the side wall of the collection box.

[0018] In some embodiments, a sealing gasket is provided between the sealing cover and the collection box.

[0019] Compared with the prior art, the solution shown in the embodiment of the present application has the following beneficial effects:

[0020] 1. When collecting serum, the blood drawing device draws blood from the animal's body. The blood enters the blood cavity through the blood inlet tube and the main inlet tube in sequence. Under a certain pressure, the serum in the blood passes through the filter membrane and enters the serum cavity. The serum in the serum cavity is collected into a designated container through the third discharge tube and the fourth discharge tube in sequence. The blood in the blood cavity that has been filtered out of the serum is returned to the animal through the first discharge tube, the second discharge tube, and the blood transfusion device in sequence. In addition, the blood that has been filtered out of the serum can also be supplemented with liquids such as physiological saline and glucose through the infusion tube to provide certain nutritional support for the animal and avoid animal death. In this way, serum collection can be achieved without sacrificing the animal, and the animal is basically painless throughout the whole process, effectively reducing the consumption of animals during the serum extraction process and lowering the cost of vaccine production.

[0021] 2. Before use, open the first control valve. High-temperature steam enters the blood chamber through the steam inlet pipe and the main inlet pipe, and simultaneously enters the blood inlet pipe through the steam inlet pipe. As the steam fills the blood chamber, it also gradually fills the serum chamber through the filter membrane. Then, open the second and third control valves. While steam continues to flow into the steam inlet pipe, steam simultaneously exits the blood chamber through the first and second discharge pipes, and exits the serum chamber through the third and fourth discharge pipes. After a certain period of time, the main inlet pipe, blood inlet pipe, blood chamber, filter membrane, serum chamber, first, second, third, and fourth discharge pipes are all steam-sterilized. Steam can effectively reach the hard-to-sterilize corners of these components. Compared to traditional disinfection methods using disinfectants, the disinfection is more comprehensive and thorough, ensuring that the final extracted serum is not contaminated, avoiding impacts on subsequent vaccine production. In addition, it also ensures the cleanliness of the path for blood transfusion back into the animal, preventing infection in the collected animal and improving the animal's survival rate. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 This is a schematic diagram of the structure of a serum collector for vaccine production provided in Example 1 of the present utility model;

[0023] Figure 2 This is a schematic diagram of the structure of a serum collector for vaccine production provided in Example 2 of the present utility model;

[0024] Figure 3 This is a partial adaptation diagram of the sealing cover and the collection box used in the third embodiment of the present utility model;

[0025] Figure 4 This is a schematic diagram of the assembly of the frame and the collection box used in the fourth embodiment of the present utility model;

[0026] Description of reference numerals:

[0027] 1. Collection chamber; 101. Blood chamber; 102. Serum chamber; 110. Collection box; 120. Sealing cover; 121. Sealing top plate; 122. Sealing enclosure; 2. First control valve; 3. Second control valve; 4. Third control valve; 5. Filter membrane; 6. Steam inlet pipe; 7. Fluid infusion pipe; 8. Main inlet pipe; 9. Blood inlet pipe; 10. First discharge pipe; 11. Second discharge pipe; 12. Third discharge pipe; 13. Fourth discharge pipe; 14. Second lower discharge pipe; 15. Third lower discharge pipe; 16. Pressurization pipe; 17. Pressurization valve; 18. Pressure relief pipe; 19. Pressure relief valve; 20. Frame; 2001. Slot; 21. Buckle; 2110. Fixing plate; 2120. First elastic plate; 2130. Second elastic plate; 2140. Auxiliary positioning plate; 22. Limiting protrusion. DETAILED DESCRIPTION

[0028] In order to make the technical problems, technical solutions and beneficial effects to be solved by the present invention more clearly understood, the present invention is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the present invention.

[0029] In the claims, description and the above-mentioned drawings of the present utility model, unless otherwise clearly defined, the use of terms such as "first", "second" or "third" is to distinguish different objects rather than to describe a specific order.

[0030] In the claims, specification and the above-mentioned drawings of the present utility model, unless otherwise expressly defined, directional words, such as the terms "center", "lateral", "longitudinal", "horizontal", "vertical", "top", "bottom", "inside", "outside", "up", "down", "front", "back", "left", "right", "clockwise", "counterclockwise", "high", "low", etc., indicating directions or positional relationships are based on the directions and positional relationships shown in the drawings, and are only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific direction or be constructed and operated in a specific direction, and therefore cannot be understood as limiting the specific protection scope of the present utility model.

[0031] In the claims, specification and the above drawings of the present utility model, unless otherwise clearly defined, if the terms "fixed connection" or "fixed connection" are used, they should be understood in a broad sense, that is, any connection method without any displacement relationship and relative rotation relationship between the two parties, that is to say, including non-detachable fixed connection, detachable fixed connection, integral connection and fixed connection through other devices or elements.

[0032] In the claims, description and drawings of the present utility model, if the terms "include", "have" and their variations are used, they are intended to mean "including but not limited to".

[0033] Please also refer to Figure 1 and Figure 2The serum collector for vaccine production provided by the present invention is now described. The serum collector includes a collection chamber 1, a first control valve 2, a second control valve 3, and a third control valve 4. A filter membrane 5 is provided within the collection chamber 1, separating the inner cavity of the collection chamber 1 into a blood chamber 101 and a serum chamber 102, arranged sequentially from top to bottom. The filter membrane 5 is used to filter serum. The first control valve 2 connects the outlet of the blood inlet pipe 9, the outlet of the steam inlet pipe 6, the outlet of the infusion pipe 7, and the inlet of the main inlet pipe 8, the outlet of which is connected to the blood chamber 101. The second control valve 3 connects the outlet of the first discharge pipe 10 and the inlet of the second discharge pipe 11. The inlet of the first discharge pipe 10 is connected to the blood chamber 101, and the outlet of the second discharge pipe 11 is connected to a blood transfusion device. The third control valve 4 connects the outlet of the third discharge pipe 12 and the inlet of the fourth discharge pipe 13. The inlet of the third discharge pipe 12 is connected to the serum chamber 102.

[0034] When extracting serum, the first control valve 2 is first opened, while the second control valve 3 and the third control valve 4 are closed. After a period of filtration, the second control valve 3 and the third control valve 4 are opened accordingly to collect the serum, and the blood after the serum is filtered is returned to the animal.

[0035] In the disinfection state, the first control valve 2 is in a state where the steam inlet pipe 6 and the main inlet pipe 8 are connected to each other, and the steam inlet pipe 6 and the blood inlet pipe 9 are connected to each other, while the steam inlet pipe 6 and the fluid infusion pipe 7 are blocked, and the main inlet pipe 8 and the fluid infusion pipe 7 are blocked; or, the first control valve 2 is in a state where the steam inlet pipe 6 and the main inlet pipe 8 are connected to each other, and the steam inlet pipe 6 and the blood inlet pipe 9 are connected to each other, the steam inlet pipe 6 and the fluid infusion pipe 7 are connected to each other, and the main inlet pipe 8 and the fluid infusion pipe 7 are connected to each other.

[0036] In this embodiment, the temperature of the steam is controlled at 115°C to 130°C (for example, 118°C, 120°C, or 125°C), and the time for passing steam for sterilization is controlled at 50 minutes to 70 minutes (for example, 55 minutes, 60 minutes, or 65 minutes).

[0037] In this embodiment, the molecular weight cut-off of the filter membrane 5 is 100 kD to 300 kD (e.g., 120 kD, 150 kD, 200 kD, or 250 kD). The filter membrane 5 filters a portion of the serum from the blood into the serum chamber 102, while the majority of the serum and blood components can be returned to the animal being collected, ensuring that the animal is not harmed.

[0038] In this embodiment, the first control valve 2, the second control valve 3 and the third control valve 4 are all solenoid valves, and their specific passage settings are set according to specific usage requirements. The first control valve 2, the second control valve 3 and the third control valve 4 can all be purchased directly from the market and can meet the on-off control of each pipeline. These are common knowledge for those skilled in the art, so they will not be described in detail.

[0039] The serum collector for vaccine production provided in this embodiment has the following beneficial effects compared with the prior art:

[0040] 1. When collecting serum, the blood drawing device draws blood from the animal's body. The blood enters the blood chamber 101 through the blood inlet tube 9 and the main inlet tube 8 in sequence. Under a certain pressure, the serum in the blood passes through the filter membrane 5 and enters the serum chamber 102. The serum in the serum chamber 102 is collected into a designated container through the third discharge tube 12 and the fourth discharge tube 13 in sequence. The blood in the blood chamber 101 after the serum is filtered out is returned to the animal through the first discharge tube 10, the second discharge tube 11, and the blood transfusion device in sequence. In addition, the blood after the serum is filtered out can also be supplemented with physiological saline, glucose, and other liquids through the infusion tube 7 to provide certain nutritional support for the animal and prevent the animal from dying. In this way, serum collection can be achieved without sacrificing the animal, and the animal is basically painless throughout the process, effectively reducing the consumption of animals during the serum extraction process and lowering the cost of vaccine production.

[0041] 2. Before use, open the first control valve 2. High-temperature steam enters the blood cavity 101 through the steam inlet pipe 6 and the main inlet pipe 8 at one time, and enters the blood inlet pipe 9 through the steam inlet pipe 6 at the same time. When the steam fills the blood cavity 101, the steam also passes through the filter membrane 5 and gradually fills the serum cavity 102. Then open the second control valve 3 and the third control valve 4. While steam continues to flow into the steam inlet pipe 6, the steam also simultaneously passes through the first discharge pipe 10 and the second discharge pipe 11 to discharge the blood cavity 101, and passes through the third discharge pipe 12 and the fourth discharge pipe 13 to discharge the serum cavity 102. After a certain period of time, the main inlet tube 8, blood inlet tube 9, blood cavity 101, filter membrane 5, serum cavity 102, first discharge tube 10, second discharge tube 11, third discharge tube 12 and fourth discharge tube 13 can all be steam sterilized, and the steam can effectively reach the dead corners of the above components that are difficult to disinfect. Compared with the traditional method of disinfection with disinfectant, the disinfection is more comprehensive and sufficient, ensuring that the finally extracted serum is not contaminated, avoiding affecting the subsequent vaccine production. In addition, it also ensures the cleanliness of the path for returning the blood to the animal's body, avoiding infection of the collected animals, and improving the survival rate of the animals.

[0042] In some embodiments, see Figure 1 and Figure 2A main inlet is provided at the upper portion of one side of the blood chamber 101, and the main inlet is connected to the outlet end of the main inlet tube 8; a first outlet is provided at the bottom portion of the other side of the blood chamber 101, and the first outlet is connected to the inlet end of the first outlet tube 10. In this embodiment, the main inlet is located at the upper portion of the blood chamber 101, allowing blood to enter the blood chamber 101 more smoothly and encounter less resistance; the first outlet is located at the bottom portion of the blood chamber 101, and under the action of gravity, blood can be more easily discharged from the blood chamber 101; in addition, because the main inlet and the first outlet are located on opposite sides of the blood chamber 101, respectively, turbulence of blood in the blood chamber 101 can be avoided while ensuring complete filtration, and excessive gas can be prevented from mixing into the blood. This not only improves the smoothness of blood discharge, but also reduces the risk of blood being re-infused into the animal's body.

[0043] In some embodiments, see Figure 1 and Figure 2 A third outlet is provided at the bottom of one side of the serum chamber 102, and the third outlet is connected to the inlet end of the third outlet tube 12. The third outlet is located at the bottom of the serum chamber 102. Under the action of gravity, the serum is more easily discharged from the serum chamber 102, thereby improving the serum collection efficiency.

[0044] In some embodiments, see Figure 1 and Figure 2 The vaccine production serum collector further includes a second lower drain pipe 14, and the second control valve 3 is connected to the inlet end of the second lower drain pipe 14. The second lower drain pipe 14 can drain liquid (such as blood or condensed water) accumulated at the bottom of the second control valve 3, keeping the interior of the second control valve 3 clean and dry.

[0045] In some embodiments, see Figure 1 and Figure 2 The vaccine production serum collector also includes a third lower drain pipe 15, to which the third control valve 4 is connected. The third lower drain pipe 15 drains liquid (e.g., blood or condensed water) that accumulates at the bottom of the third control valve 4, keeping the interior of the third control valve 4 clean and dry.

[0046] It should be noted that the above-mentioned schemes of setting the second lower pipe 14 and the third lower pipe 15 can be used separately or in combination. This embodiment exemplarily shows the scheme of setting the second lower pipe 14 and the third lower pipe 15 at the same time.

[0047] Based on the above embodiment, a circulation channel is formed inside the second control valve 3 and the third control valve 4, and the second lower discharge pipe 14 and the third lower discharge pipe 15 are connected to the lowest end of the circulation channel in each control valve to discharge residual substances in the circulation channel.

[0048] In some embodiments, see Figure 2A booster pumping device is provided at the blood inlet tube 9. During filtration, the pressure in the blood chamber 101 can be provided by the booster pumping device, with the pressure controlled within a range of 0.15 kPa to 0.25 kPa (e.g., 0.17 kPa, 0.20 kPa, or 0.23 kPa). Specific implementations of the booster pumping device include, but are not limited to, a peristaltic pump connected to the blood inlet tube 9.

[0049] Based on the above embodiments, see Figure 2 In order to precisely control the internal air pressure of the blood chamber 101, a pressure sensor is also provided in the blood chamber 101. The pressure sensor is positioned close to the filter membrane 5 and can more accurately sense the filtration pressure. On this basis, through the communication connection between the booster pumping device and the pressure sensor, if the pressure sensor senses that the filtration pressure is less than the minimum value, the pumping volume of the booster pumping device is increased; if the pressure sensor senses that the filtration pressure is within the normal operating air pressure range, the booster pumping device is maintained in the current operating state until serum separation is completed; if the pressure sensor senses that the filtration pressure is higher than the maximum value, the pumping volume of the booster pumping device is reduced until the air pressure returns to the normal operating air pressure range. This embodiment can achieve precise control of the filtration pressure, prevent the filtration pressure from being too low and affecting the serum filtration efficiency, and prevent the filtration pressure from being too high and causing damage to the filter membrane 5, thereby ensuring the reliability and stability of the operation.

[0050] In some embodiments, see Figure 2 The collection chamber 1 includes a collection box 110 with an open top, and a sealing cover 120 that is openable and closable and is located on the top opening of the collection box 110. A filter membrane 5 is located in the middle of the collection box 110, and a pressure sensor is located above the filter membrane 5 and connected to the inner wall of the collection box 110. Opening the sealing cover 120 exposes the filter membrane 5, pressure sensor, and other components inside the collection box 110, facilitating maintenance. At the same time, when the sealing cover 120 is closed, it maintains the sealing of the collection box 110, preventing external air from entering the collection box 110 and contaminating the blood during the filtration process.

[0051] Based on the above embodiments, see Figure 2 and Figure 3The sealing cover 120 includes a sealing top plate 121 and a sealing enclosure 122 surrounding the sealing top plate 121. The sealing enclosure 122 is arranged perpendicular to the sealing top plate 121. The sealing enclosure 122 on one side is rotatably connected to the top edge of the collection box 110, and the sealing enclosure 122 on the other side is clamped to the corresponding side of the top of the collection box 110 through a buckle 21 component, so that the sealing edge of the sealing enclosure 122 is tightly abutted against the top surface of the collection box 110. After the sealing cover 120 is opened, it will not separate from the collection box 110, avoiding damage or loss of parts caused by sealing the cover 120 alone. When closed, the buckle 21 can ensure effective sealing and can be easily released when opened, making it more convenient to open and close the sealing cover 120. The structure of the sealing cover 120 itself can ensure effective sealing contact with the top of the collection box 110, ensuring the sealing inside the collection box 110 during operation.

[0052] In specific implementation, the buckle 21 assembly includes a hook that is rotatably connected to the outer periphery of the sealing enclosure 122, and also includes a card plate arranged on the outer periphery of the top of the collection box 110. When engaged, the hook of the hook is tightly hooked to the card plate, and the hook can be bent outward to release the engagement with the card plate.

[0053] In some embodiments, in order to facilitate maintenance of the filter membrane 5 , the filter membrane 5 is detachably connected to the collection box 110 .

[0054] Based on the above embodiments, see Figure 4 The periphery of the filter membrane 5 is connected with a frame 20, and the frame 20 is detachably connected to the side wall of the collection box 110, reducing the difficulty of setting the detachable connection structure.

[0055] In some specific implementations of detachable connections, see Figure 4A slot 2001 is provided on the side of the frame 20 facing away from the filter membrane 5. A corresponding spring-loaded latch 21 is provided on the sidewall of the collection box 110. The latch 21 engages with the slot 2001. Specifically, the latch 21 comprises a fixed plate 2110, a first elastic plate 2120, a second elastic plate 2130, and an auxiliary positioning plate 2140, which are integrally connected from top to bottom. The fixed plate 2110 is attached to the inner wall of the collection box 110 via threaded fasteners or other means. The first elastic plate 2120 and the second elastic plate 2130 are arranged at an angle, forming a triangular latching protrusion with the tip pointing toward the frame 20. The auxiliary positioning plate 2140 slides in contact with the inner wall of the collection box 110, increasing the contact area between the end of the second elastic plate 2130 and the collection box 110. This prevents deformation of the triangular latching protrusion during engagement, which could cause the end of the second elastic plate 2130 to scratch the inner wall of the collection box 110. During installation, the frame 20 and the filter membrane 5 are placed into the collection box 110 from top to bottom. As the frame 20 descends, the frame 20 squeezes the first elastic sheet 2120, and the triangular snap-fit ​​protrusion is squeezed; when the tip of the triangular snap-fit ​​protrusion corresponds to the slot 2001, the triangular snap-fit ​​protrusion releases elastic potential energy, and the first elastic sheet 2120 and the second elastic sheet 2130 are snapped into the slot 2001, and the snap-fit ​​is completed; the disassembly can be completed by pulling the frame 20 upwards, and the disassembly and assembly operation is very simple.

[0056] More specifically, in order to facilitate the disassembly of the frame 20 , a handle is provided on the upper surface of the frame 20 , so that the operator can use a tool such as a hook to lift the frame 20 and release the connection between the frame 20 and the buckle 21 .

[0057] In some specific embodiments, a sealing bubble tube is provided on the side of the frame 20 facing away from the filter membrane 5. The sealing bubble tube extends along the long axis of the frame 20. After installation, the sealing bubble tube tightly abuts the inner wall of the collection box 110, forming a seal around the frame 20 and preventing blood from directly entering the serum chamber 102 through the gap between the edge and the collection box 110. More specifically, to reduce manufacturing difficulty and improve reliability and stability, the frame 20 is made of plastic and the sealing bubble tube is made of silicone. The sealing bubble tube and the frame 20 are integrally formed by secondary injection molding to avoid a connection gap between the two.

[0058] In some embodiments, see Figure 3 The sealing edge of the sealing panel 122 forms a first sealing slope, and the top surface of the collection box 110 forms a second sealing slope. The first sealing slope fits against the second sealing slope, forming a gradually downwardly sloping joint between the sealing panel 122 and the collection box 110. This joint ensures a reliable seal while also guiding blood, preventing it from easily spilling from the joint area between the sealing cover 120 and the collection box 110.

[0059] More specifically, the first sealing bevel and / or the second sealing bevel are covered with an elastic sealing layer, which can further improve the sealing performance of the connection between the two.

[0060] On the basis of the above embodiment, a limiting protrusion 22 is formed on the outer periphery of the sealing enclosure 122 , and the limiting protrusion 22 abuts against the top of the collection box 110 to limit the downward displacement of the sealing enclosure 122 .

[0061] In some embodiments, a sealing gasket is provided between the sealing cover 120 and the collection box 110 to ensure the sealing of the docking area between the two.

[0062] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent replacements and improvements made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

Claims

1. A serum collector for vaccine production, characterized in that: include: A collection chamber (1), wherein a filter membrane (5) is provided inside the collection chamber (1), wherein the filter membrane (5) separates the inner cavity of the collection chamber (1) into a blood cavity (101) and a serum cavity (102) sequentially distributed from top to bottom, and the filter membrane (5) is used for filtering serum; A first control valve (2) is connected to the outlet end of the blood inlet tube (9), the outlet end of the steam inlet tube (6), the outlet end of the infusion tube (7) and the inlet end of the main inlet tube (8), wherein the outlet end of the main inlet tube (8) is connected to the blood chamber (101); a second control valve (3) connected to the outlet end of the first discharge tube (10) and the inlet end of the second discharge tube (11), wherein the inlet end of the first discharge tube (10) is connected to the blood chamber (101), and the outlet end of the second discharge tube (11) is connected to the blood transfusion device; as well as The third control valve (4) is connected to the outlet end of the third discharge pipe (12) and the inlet end of the fourth discharge pipe (13), and the inlet end of the third discharge pipe (12) is connected to the serum chamber (102).

2. The serum collector for vaccine production according to claim 1, wherein: The serum collector for vaccine production further comprises a second lower pipe (14), and the second control valve (3) is connected to the inlet end of the second lower pipe (14).

3. The serum collector for vaccine production according to claim 1, wherein: The serum collector for vaccine production further comprises a third lower pipe (15), and the third control valve (4) is connected to the inlet end of the third lower pipe (15).

4. The serum collector for vaccine production according to claim 1, wherein: A pressure-boosting pumping device is provided at the blood inlet tube (9).

5. The serum collector for vaccine production according to claim 4, characterized in that: A pressure sensor is also provided in the blood chamber (101), and the booster pumping device is communicatively connected to the pressure sensor.

6. The serum collector for vaccine production according to claim 5, characterized in that: The collection chamber (1) comprises a collection box (110) with an opening at the top, and also comprises a sealing cover (120) which is openable and closable and is arranged at the top opening of the collection box (110); the filter membrane (5) is arranged in the middle of the collection box (110), and the pressure sensor is arranged above the filter membrane (5) and is connected to the inner wall of the collection box (110).

7. The serum collector for vaccine production according to claim 6, characterized in that: The sealing cover (120) includes a sealing top plate (121) and a sealing enclosure (122) arranged around the sealing top plate (121). The sealing enclosure (122) is arranged vertically to the sealing top plate (121). The sealing enclosure (122) on one side is rotatably connected to the top edge of the collection box (110), and the sealing enclosure (122) on the other side is snap-fitted to the corresponding side of the top of the collection box (110) through a snap-fit ​​(21) assembly, so that the sealing edge of the sealing enclosure (122) is in close contact with the top surface of the collection box (110).

8. The serum collector for vaccine production according to claim 6, wherein: The filter membrane (5) is detachably connected to the collection box (110).

9. The serum collector for vaccine production according to claim 8, characterized in that: The outer periphery of the filter membrane (5) is connected to a frame (20), and the frame (20) is detachably connected to the side wall of the collection box (110).

10. The serum collector for vaccine production according to claim 6, wherein: A sealing gasket is provided between the sealing cover (120) and the collection box (110).

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