Cleaning device for free protein on surface of biological chip sample

Abstract

The utility model relates to the technical field of biochip sample cleaning, in particular to a biochip sample surface free protein cleaning device which comprises a cleaning frame, a clamping groove and a taking-out assembly, the clamping groove is installed on the inner side of the cleaning frame, the taking-out assembly comprises an installation shell, a sliding frame, an abutting plate, a pulling block and a driving component, and the installation shell is fixedly connected with the cleaning frame. The sliding frame is slidably connected with the mounting shell and located on the side, close to the cleaning frame, of the mounting shell, the abutting plate is fixedly connected with the sliding frame and located on the side, away from the mounting shell, of the sliding frame, the pulling block is connected with the sliding frame through a driving component, and the driving component supports the pulling block. A specified chip sample can be taken out more quickly and conveniently, and the practicability of equipment is greatly improved.

Description

Technical Field

[0001] The utility model relates to the technical field of biochip sample cleaning, in particular to a device for cleaning free proteins on the surface of a biochip sample. Background Art

[0002] In the existing technology, free proteins are removed only by water washing, and there is no special technology or device to avoid the "tailing" phenomenon. Due to the lack of good cleaning equipment, the free proteins are easily covalently or non-covalently bound to other positions on the chip sample during the cleaning process relying on the existing chip cleaning box, increasing the degree of "tailing", making it difficult to completely remove the proteins and incomplete protein cleaning.

[0003] The existing patent CN212883845U describes a device for cleaning free proteins on the surface of biochip samples, which includes a chip cleaning box, a chip cleaning rack, an end cover, and an automatic sampling pump. The chip cleaning box has a water inlet and a water outlet on two opposing sides of the upper portion, and a latching mechanism is provided at the bottom of the chip cleaning box. The chip cleaning rack is disposed within the chip cleaning box and is detachably connected to the latching mechanism. The end cover is fitted onto the upper end of the chip cleaning box, and the automatic sampling pump is connected to the water inlet. The device for cleaning free proteins on the surface of biochip samples disclosed in the utility model completely removes proteins and improves the cleaning effect. It also improves the repeatability of protein cleaning, reduces deviations between different batches, saves labor costs, and solves the problem of low efficiency in removing free proteins. The chip cleaning rack can store multiple biochip samples to be cleaned, allowing a large number of chip samples to be cleaned at one time, greatly improving cleaning efficiency.

[0004] In the existing equipment, it is possible to clean multiple chips at the same time. However, when cleaning multiple chips, the gaps between the chips are small, and a certain chip cannot be taken out quickly, which makes it inconvenient to use. Utility Model Content

[0005] The purpose of the utility model is to provide a device for cleaning free proteins on the surface of biochip samples, which solves the problem that when cleaning multiple chips, the gaps between the chips are small, and a chip cannot be quickly taken out, which is inconvenient to use.

[0006] To achieve the above-mentioned purpose, the utility model provides a device for cleaning free proteins on the surface of biochip samples, comprising a cleaning rack, a card slot and a removal component, wherein the card slot is installed on the inner side of the cleaning rack, and the removal component comprises a mounting shell, a sliding rack, an abutment plate, a pulling block and a driving member, the mounting shell is fixedly connected to the cleaning rack and is located on the side of the cleaning rack away from the card slot, the sliding rack is slidably connected to the mounting shell and is located on the side of the mounting shell close to the cleaning rack, the abutment plate is fixedly connected to the sliding rack and is located on the side of the sliding rack away from the mounting shell, the pulling block is connected to the sliding rack through the driving member, and the driving member supports the pulling block.

[0007] Wherein, the removal assembly also includes a first clamping plate and a second clamping plate, the first clamping plate is fixedly connected to the abutment plate and is located on the side of the abutment plate close to the sliding frame; the second clamping plate is fixedly connected to the abutment plate and is located on the side of the abutment plate close to the first clamping plate.

[0008] Wherein, the driving component includes a connecting rod, a mounting block and an elastic element, the connecting rod is fixedly connected to the sliding frame, and is located on the side of the sliding frame away from the abutment plate, and is connected to the pulling block; the mounting block is fixedly connected to the mounting shell, and is located on the side of the mounting shell away from the sliding frame; the elastic element is installed on the mounting block, and the elastic element drives the sliding frame to move.

[0009] Among them, the elastic element includes an abutment block and a spring, the abutment block is fixedly connected to the sliding frame and is located on the side of the sliding frame close to the connecting rod; the spring is sleeved on the outside of the connecting rod, and the two ends of the spring respectively abut the mounting block and the abutment block.

[0010] In which, the removal assembly also includes a reinforcement block and a connecting frame, the reinforcement block is fixedly connected to the connecting rod and is located on the side of the connecting rod close to the sliding frame; the connecting frame is fixedly connected to the reinforcement block and is located on the side of the reinforcement block away from the connecting rod, and is connected to the sliding frame.

[0011] The cam is mounted on the outer side of the cleaning rack by bolts, and the sliding rack is slidably mounted on the inner side of the mounting shell, and the sliding rack portion is extended out of the outer side of the mounting shell. The mounting shell has a sliding groove that cooperates with the sliding rack, so that the sliding rack can slide up and down stably in the mounting shell, and the abutment plate is mounted on the side where the sliding rack extends out of the mounting shell by bolts, and abuts against the chip through the abutment plate, so that the abutment plate can drive the chip to move. The pulling block is mounted on the sliding rack by the driving component, and the driving component enables the pulling block to pull the sliding rack to move. The pulling block pulls the sliding rack by the driving component, so that the sliding rack drives the abutment plate to move upward, and the abutment plate drives the chip to move upward, thereby achieving faster and more convenient removal of the specified chip sample, greatly improving the practicality of the device. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art.

[0013] Figure 1 It is a schematic diagram of the overall structure of a device for cleaning free proteins on the surface of a biochip sample according to the first embodiment of the present utility model.

[0014] Figure 2 It is a schematic diagram of the overall structure of the removal component of the first embodiment of the present utility model.

[0015] Figure 3 This is a schematic diagram of the installation of the first clamping plate and the second clamping plate of the first embodiment of the present utility model.

[0016] In the figure: 100-cleaning rack, 101-card slot, 103-mounting shell, 104-sliding rack, 105-abutment plate, 106-pulling block, 107-first card plate, 108-second card plate, 109-connecting rod, 110-mounting block, 111-abutment block, 112-spring, 113-reinforcement block, 114-connecting rack. DETAILED DESCRIPTION

[0017] The embodiments of the present invention are described in detail below, and examples of the embodiments are shown in the accompanying drawings. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to be used to explain the present invention, but should not be understood as limiting the present invention.

[0018] The first embodiment of this application is:

[0019] See also Figures 1 to 3 , Figure 1This is a schematic diagram of the overall structure of a device for cleaning free proteins on the surface of a biochip sample according to the first embodiment of the utility model. Figure 2 This is a schematic diagram of the overall structure of the removal assembly of the first embodiment of the utility model. Figure 3 This is a schematic diagram of the installation of the first clamping plate and the second clamping plate of the first embodiment of the present utility model.

[0020] The present invention provides a device for cleaning free proteins on the surface of biochip samples, comprising a cleaning rack 100, a card slot 101 and a removal assembly, wherein the removal assembly comprises a mounting shell 103, a sliding rack 104, an abutment plate 105, a pulling block 106, a driving member, a first clamping plate 107 and a second clamping plate 108, the driving member comprises a connecting rod 109, a mounting block 110 and an elastic element, the elastic element comprises an abutment block 111 and a spring 112, the removal assembly further comprises a reinforcing block 113 and a connecting rack 114, and this solution solves the problem that when cleaning multiple chips, the gaps between the chips are small, a certain chip cannot be quickly removed, and the use is relatively inconvenient.

[0021] For this specific embodiment, the card slot 101 is installed on the inner side of the cleaning rack 100. The cleaning rack 100 and the card slot 101 are both the chip cleaning rack and the card positioning mechanism described in the existing patent technology CN212883845U, a device for cleaning free proteins on the surface of a biochip sample. The chip is fixed on the cleaning rack 100 through the card slot 101, thereby realizing the cleaning of a large number of chip samples at one time, greatly improving the cleaning efficiency. Through this solution, the specified chip sample can be quickly and conveniently removed, greatly improving the practicality of the equipment.

[0022] The mounting shell 103 is fixedly connected to the cleaning rack 100 and is located on a side of the cleaning rack 100 away from the card slot 101. The sliding rack 104 is slidably connected to the mounting shell 103 and is located on a side of the mounting shell 103 close to the cleaning rack 100. The abutment plate 105 is fixedly connected to the sliding rack 104 and is located on a side of the sliding rack 104 away from the mounting shell 103. The pulling block 106 is connected to the sliding rack 104 through the driving member, and the driving member supports the pulling block 106. The mounting shell 103 is mounted on the outside of the cleaning rack 100 by bolts, and the sliding rack 104 is slidably mounted on the inner side of the mounting shell 103, so that the sliding rack 104 partially extends out of the outside of the mounting shell 103. The mounting shell 103 has a fixed connection with the sliding rack 1 04 cooperates with the slide groove, so that the sliding frame 104 can slide up and down stably in the mounting shell 103, and the abutment plate 105 is installed on the side of the sliding frame 104 extending out of the mounting shell 103 by bolts, and abuts against the chip through the abutment plate 105, so that the abutment plate 105 can drive the chip to move, and the pulling block 106 is installed on the sliding frame 104 through the driving component, and the pulling block 106 can pull the sliding frame 104 to move through the driving component, and the pulling block 106 pulls the sliding frame 104 to move through the driving component, so that the sliding frame 104 drives the abutment plate 105 to move upward, and the abutment plate 105 drives the chip to move upward, thereby realizing fast and convenient removal of the specified chip sample, greatly improving the practicality of the equipment.

[0023] Secondly, the first clamping plate 107 is fixedly connected to the abutment plate 105 and is located on the side of the abutment plate 105 close to the sliding frame 104; the second clamping plate 108 is fixedly connected to the abutment plate 105 and is located on the side of the abutment plate 105 close to the first clamping plate 107. The first clamping plate 107 is installed above the abutment plate 105 by bolts, and the first clamping plate 107 is installed on the side of the abutment plate 105 close to the first clamping plate 107 by bolts. The chip is fixed on the abutment plate 105 by the cooperation of the first clamping plate 107 and the second clamping plate 108, so that the abutment plate 105 can stably drive the chip to move.

[0024] At the same time, the connecting rod 109 is fixedly connected to the sliding frame 104 and is located on the side of the sliding frame 104 away from the abutment plate 105, and is connected to the pulling block 106; the mounting block 110 is fixedly connected to the mounting shell 103 and is located on the side of the mounting shell 103 away from the sliding frame 104; the elastic element is mounted on the mounting block 110, and the elastic element drives the sliding frame 104 to move, and the connecting rod 109 is mounted on the side of the sliding frame 104 close to the mounting shell 103 by a bolt, and one side of the connecting rod 109 The end passes through the mounting shell 103, and the pulling block 106 is installed on the side of the connecting rod 109 away from the sliding frame 104 by bolts. The pulling block 106 pulls the sliding frame 104 to move through the connecting rod 109. The mounting block 110 is installed above the inner side of the mounting shell 103 by bolts, and the connecting rod 109 passes through the mounting block 110. The elastic element is installed on the mounting block 110, and the sliding frame 104 is moved downward by the elastic element, thereby ensuring that the chip can be completely placed on the cleaning rack 100.

[0025] In addition, the abutment block 111 is fixedly connected to the sliding frame 104 and is located on the side of the sliding frame 104 close to the connecting rod 109; the spring 112 is sleeved on the outside of the connecting rod 109, and the two ends of the spring 112 respectively abut the mounting block 110 and the abutment block 111, and the abutment block 111 is installed on the side of the sliding frame 104 close to the connecting rod 109 by bolts, and the spring 112 is sleeved on the outside of the connecting rod 109, and the two ends of the spring 112 respectively abut against the mounting block 110 and the abutment block 111, and the sliding frame 104 is moved downward by the elastic force of the spring 112, thereby ensuring that the chip can be completely placed on the cleaning rack 100.

[0026] Finally, the reinforcement block 113 is fixedly connected to the connecting rod 109 and is located on a side of the connecting rod 109 close to the sliding frame 104; the connecting frame 114 is fixedly connected to the reinforcement block 113 and is located on a side of the reinforcement block 113 away from the connecting rod 109, and is connected to the sliding frame 104. The reinforcement block 113 is installed on the side of the connecting rod 109 close to the sliding frame 104 by bolts, so that the connecting rod 109 can drive the reinforcement block 113 to move, and the connecting frame 114 is installed on the side of the reinforcement block 113 away from the connecting rod 109 by bolts, and the other side of the connecting frame 114 is connected to the sliding frame 104. Through the cooperation of the reinforcement block 113 and the connecting frame 114, the sliding frame 104 can move more stably on the mounting shell 103.

[0027] When using the device for cleaning free proteins on the surface of a biochip sample of this embodiment, when it is necessary to take out a specified chip, the pulling block 106 next to the chip is pulled, and the pulling block 106 pulls the sliding frame 104 to move through the connecting rod 109, so that the sliding frame 104 drives the abutment plate 105 to move, and the abutment plate 105 drives the chip to move upward, thereby achieving faster and more convenient removal of the specified chip sample, greatly improving the practicality of the device.

[0028] The above disclosure is merely one or more preferred embodiments of the present application and is not intended to limit the scope of the present application. A person skilled in the art will understand that all or part of the processes of the above embodiments and equivalent changes made in accordance with the claims of the present application are still within the scope of the present application.

Claims

1. A device for cleaning free proteins on the surface of a biochip sample, comprising a cleaning rack and a card slot, wherein the card slot is installed on the inner side of the cleaning rack, characterized in that: Also includes removing components; The taking-out assembly includes a mounting shell, a sliding frame, an abutment plate, a pulling block and a driving member. The mounting shell is fixedly connected to the cleaning frame and is located on a side of the cleaning frame away from the card slot. The sliding frame is slidably connected to the mounting shell and is located on a side of the mounting shell close to the cleaning frame. The abutment plate is fixedly connected to the sliding frame and is located on a side of the sliding frame away from the mounting shell. The pulling block is connected to the sliding frame through the driving member, and the driving member supports the pulling block.

2. The cleaning device for free proteins on the surface of a biochip sample according to claim 1, characterized in that: The removal assembly also includes a first card plate and a second card plate, the first card plate is fixedly connected to the abutment plate and is located on a side of the abutment plate close to the sliding frame; the second card plate is fixedly connected to the abutment plate and is located on a side of the abutment plate close to the first card plate.

3. The cleaning device for free protein on the surface of a biochip sample according to claim 1, characterized in that: The driving component includes a connecting rod, a mounting block and an elastic element. The connecting rod is fixedly connected to the sliding frame and is located on a side of the sliding frame away from the abutment plate, and is connected to the pulling block; the mounting block is fixedly connected to the mounting shell and is located on a side of the mounting shell away from the sliding frame; the elastic element is mounted on the mounting block, and the elastic element drives the sliding frame to move.

4. The device for cleaning free proteins on the surface of a biochip sample according to claim 3, characterized in that: The elastic element includes an abutment block and a spring. The abutment block is fixedly connected to the sliding frame and is located on a side of the sliding frame close to the connecting rod. The spring is sleeved on the outside of the connecting rod, and the two ends of the spring respectively abut the mounting block and the abutment block.

5. The device for cleaning free proteins on the surface of a biochip sample according to claim 4, characterized in that: The removal assembly also includes a reinforcement block and a connecting frame, the reinforcement block is fixedly connected to the connecting rod and is located on a side of the connecting rod close to the sliding frame; the connecting frame is fixedly connected to the reinforcement block and is located on a side of the reinforcement block away from the connecting rod and is connected to the sliding frame.

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