Trans-heart systemic circulation perfusion machine

Abstract

The utility model relates to the technical field of heart perfusion, in particular to a perfusing machine through heart systemic circulation, which comprises a perfusion needle and a perfusion machine body, and the perfusion needle comprises a puncture needle, a catheter, a fixing clamp and a rubber pad; when the animal heart is punctured, the puncture needle is punctured into the left atrium of the animal heart, then the fixing clamps are clamped and fixed to the two sides of the heart, at the moment, the animal heart is protected through the rubber pads, fixation of the puncture needle is completed, finally, the catheter is connected with a perfusion machine body, and the perfusion machine body can be started for a heart perfusion experiment. According to the perfusion needle, the puncture needle inserted into the heart is doubly fixed through the mousing hook and the fixing clamp on the puncture needle, the phenomenon that the puncture needle falls off during perfusion is effectively avoided, the animal heart is protected from being damaged by the fixing clamp through the arrangement of the rubber pad, and the problem that an existing heart perfusion experiment adopts a fixed perfusion needle, so that the perfusion needle is inconvenient to use is solved. The heart tissue is easily damaged, so that the perfusate flows out.

Description

Technical Field

[0001] The utility model relates to the technical field of cardiac perfusion, in particular to a transcardiac systemic circulation perfusion machine. Background Art

[0002] Cardiac perfusion experiment is an essential first step in animal tissue sampling, and the effect of perfusion directly affects the state of the tissue, which is crucial to the success of experiments such as tissue staining. The cardiac perfusion experiment first requires exposing the animal heart, inserting the perfusion needle into the animal's left ventricle, fixing the perfusion needle, cutting the right atrial appendage, and perfusing with physiological saline and paraformaldehyde in sequence.

[0003] The difficulty in cardiac perfusion experiments, and also the key point leading to experimental failure, is that the perfusion needle must be inserted into the left ventricle and maintained in this insertion position throughout the entire perfusion process. If it is inserted too far, it will puncture the ventricle, and if it moves backward, it will fall out of the ventricle. Both situations will prevent the perfusion fluid from entering the systemic tissues through the animal's vascular circulatory system, resulting in irreversible failure of the experiment. During the experiment, the animal will experience systemic tremors due to formaldehyde perfusion, and the hydraulic pressure of the perfusion fluid will also produce reaction force and vibration on the perfusion needle. The above steps are very demanding on the experimenter's experience and technique.

[0004] Currently, there are no dedicated animal heart perfusion devices on the market. Most researchers use ordinary injection or infusion needles and flexible tubes, inserting the needle into the heart and securing the perfusion needle with a vascular clamp. However, securing the perfusion needle with a vascular clamp can easily cause irreversible mechanical damage to cardiac tissue, leading to leakage of the perfusate. Utility Model Content

[0005] The utility model aims to provide a transcardiac systemic perfusion machine, aiming to solve the problem that the existing cardiac perfusion experiments use fixed perfusion needles, which are prone to damage to cardiac tissue and cause perfusion fluid outflow.

[0006] To achieve the above-mentioned objectives, the present invention provides a transcardiac systemic circulation perfusion machine, comprising a perfusion needle and a perfusion body, wherein the perfusion needle is connected to the perfusion body, and the perfusion needle comprises a puncture needle, a catheter, a fixing clamp and a rubber pad; the puncture needle has an anti-detachment hook, and the anti-detachment hook is located on one side of the puncture needle; the catheter is connected to the puncture needle and is located on one side of the puncture needle; the fixing clamp is arranged on the outside of the catheter; the rubber pad is fixedly connected to the fixing clamp and is located on one side of the fixing clamp.

[0007] In which, the fixing clip includes an elastic clip, a mounting ring, a snap buckle and a strap. The mounting ring is arranged on the outside of the catheter. The elastic clip is fixedly connected to the mounting ring and is located on the side of the mounting ring close to the puncture needle. The snap buckle is fixedly connected to the elastic clip and is located on one side of the elastic clip. The strap is fixedly connected to the mounting ring and is located on the side of the elastic clip away from the snap buckle.

[0008] The perfusion body includes a tank injection pump and a fixed base plate. The tank injection pump is connected to the catheter and is located on the side of the catheter away from the puncture needle. The fixed base plate is fixedly connected to the tank injection pump and is located at the bottom of the tank injection pump.

[0009] Among them, the fixed base plate includes a base plate, a pressure strip and a suction cup. The base plate is fixedly connected to the tank pump and is located at the bottom of the tank pump. The pressure strip is slidingly connected to the base plate and is located on both sides of the base plate. The suction cup is fixedly connected to the pressure strip and is located at the bottom of the pressure strip.

[0010] Wherein, the filling pump has a connector, which is located on one side of the filling pump, and the pressure strip has a pull rod, which is located on the top of the pressure strip.

[0011] The utility model provides a transcardiac systemic perfusion machine. When puncturing an animal's heart, the experimenter first inserts the puncture needle into the left atrium of the animal's heart with his hands, and then clamps and fixes the fixing clamps on both sides of the heart. At this time, the animal's heart is protected by the rubber pad, and the fixation of the puncture needle is completed. Finally, the catheter is connected to the perfusion machine body, and the perfusion machine body can be started to perform a cardiac perfusion experiment. The perfusion needle is doubly fixed to the puncture needle inserted into the heart by the anti-detachment hook on the puncture needle and the setting of the fixing clamp, which effectively avoids the phenomenon of the puncture needle falling off during perfusion. The setting of the rubber pad protects the animal's heart from being damaged by the fixing clamp, thereby solving the problem that the existing cardiac perfusion experiment uses a fixed perfusion needle, which is easy to cause damage to the heart tissue and cause the perfusion fluid to flow out. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art.

[0013] Figure 1 The utility model is a structural schematic diagram of a transcardiac systemic circulation perfusion machine.

[0014] Figure 2 The utility model is a schematic diagram of a fixing clamp structure of a transcardiac systemic perfusion machine.

[0015] Figure 3 The utility model is a schematic diagram of the structure of a perfusion machine body of a transcardiac systemic perfusion machine.

[0016] In the figure: 1-perfusion needle, 2-perfusion body, 3-puncture needle, 4-anti-detachment hook, 5-catheter, 6-fixing clip, 7-rubber pad, 8-elastic clip, 9-mounting ring, 10-snapping buckle, 11-cassette, 12-infusion pump, 13-fixed base plate, 14-base plate, 15-pressure strip, 16-suction cup, 17-connector, 18-pull rod. DETAILED DESCRIPTION

[0017] The following describes in detail embodiments of the present invention, examples of which are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to explain the present invention, and should not be construed as limiting the present invention.

[0018] See also Figures 1 to 3 The utility model provides a transcardiac systemic perfusion machine, comprising a perfusion needle 1 and a perfusion body 2, wherein the perfusion needle 1 is connected to the perfusion body 2, and the perfusion needle 1 comprises a puncture needle 3, a catheter 5, a fixing clamp 6 and a rubber pad 7; the puncture needle 3 has an anti-detachment hook 4, and the anti-detachment hook 4 is located on one side of the puncture needle 3, the catheter 5 is connected to the puncture needle 3 and is located on one side of the puncture needle 3, the fixing clamp 6 is arranged on the outside of the catheter 5, and the rubber pad 7 is fixedly connected to the fixing clamp 6 and is located on one side of the fixing clamp 6.

[0019] In this embodiment, when puncturing the animal's heart, the experimenter first uses his hands to insert the puncture needle 3 into the left atrium of the animal's heart, and then clamps the fixing clip 6 on both sides of the heart. At this time, the animal's heart is protected by the rubber pad 7, that is, the fixation of the puncture needle 3 is completed. Finally, the catheter 5 is connected to the perfusion body 2, and the perfusion body 2 can be started to perform the heart perfusion experiment. The perfusion needle 1 is doubly fixed to the puncture needle 3 inserted into the heart by the anti-detachment hook 4 and the fixing clip 6 on the puncture needle 3, effectively avoiding the puncture needle 3 from falling off during perfusion. The setting of the rubber pad 7 protects the animal's heart from being damaged by the fixing clip 6, solving the problem that the existing heart perfusion experiment uses a fixed perfusion needle, which is easy to damage the heart tissue and cause the perfusion fluid to flow out.

[0020] Furthermore, the fixing clip 6 includes an elastic clip 8, a mounting ring 9, a snap buckle 10 and a strap 11. The mounting ring 9 is arranged on the outside of the catheter 5. The elastic clip 8 is fixedly connected to the mounting ring 9 and is located on the side of the mounting ring 9 close to the puncture needle 3. The snap buckle 10 is fixedly connected to the elastic clip 8 and is located on one side of the elastic clip 8. The strap 11 is fixedly connected to the mounting ring 9 and is located on the side of the elastic clip 8 away from the snap buckle 10.

[0021] In this embodiment, the setting of the mounting ring 9 provides an installation place for the elastic clip 8. When clamping and fixing the animal heart, the experimenter pulls the cassette 11 with his hands and inserts the cassette 11 into the snap buckle 10 for clamping. When the cassette 11 is pulled, the elastic clip 8 connected to the cassette 11 will approach the animal's heart and firmly press the rubber pad 7 against the animal's heart. When the cassette 11 is clamped with the snap buckle 10, the elastic clips 8 on both sides of the animal's heart will firmly clamp and fix the animal's heart, thereby fixing the animal's heart.

[0022] Furthermore, the perfusion body 2 includes a tank filling pump 12 and a fixed base plate 13. The tank filling pump 12 is connected to the catheter 5 and is located on the side of the catheter 5 away from the puncture needle 3. The fixed base plate 13 is fixedly connected to the tank filling pump 12 and is located at the bottom of the tank filling pump 12.

[0023] In this embodiment, one end of the cannulation pump 12 is connected to the catheter 5, and the other end is connected to a beaker or container filled with perfusion fluid through the catheter. When the cannulation pump 12 is powered on, the perfusion fluid is extracted and injected into the catheter 5 for the puncture needle 3 to perform a cardiac perfusion experiment. The fixed base plate 13 is used to fix the cannulation pump 12 on the desktop to prevent the cannulation pump 12 from moving on the desktop due to vibration during operation, causing the cannulation pump 12 to pull the catheter 5 and cause the catheter 5 to fall off.

[0024] Furthermore, the fixed base plate 13 includes a base plate 14, a pressure strip 15 and a suction cup 16. The base plate 14 is fixedly connected to the tank pump 12 and is located at the bottom of the tank pump 12. The pressure strip 15 is slidingly connected to the base plate 14 and is located on both sides of the base plate 14. The suction cup 16 is fixedly connected to the pressure strip 15 and is located at the bottom of the pressure strip 15.

[0025] In this embodiment, the base plate 14 provides installation conditions for the filling pump 12, and the pressure strip 15 is used to press the suction cup 16 on the table. The suction cup 16 is adsorbed on the table to fix the base plate 14, that is, the filling pump 12, to prevent the filling pump 12 from moving on the table due to vibration, causing the filling pump 12 to pull the catheter 5 and cause the catheter 5 to fall off.

[0026] Furthermore, the filling pump 12 has a connector 17 , which is located on one side of the filling pump 12 . The pressure strip 15 has a pull rod 18 , which is located on the top of the pressure strip 15 .

[0027] In this embodiment, the setting of the connecting head 17 facilitates the connection of the catheter 5 with the filling pump 12, thereby improving practicality. The setting of the pull rod 18 facilitates pulling the pressure strip 15 after the experiment to separate the suction cup 16 from the desktop.

[0028] The above disclosure is merely a preferred embodiment of the transcardiac systemic perfusion machine of the present application and is not intended to limit the scope of the present application. A person skilled in the art will understand that any equivalent changes made by implementing all or part of the processes of the above embodiment in accordance with the claims of the present application are still within the scope of the present application.

Claims

1. A transcardiac systemic perfusion machine, characterized in that: It includes a perfusion needle and a perfusion body, wherein the perfusion needle is connected to the perfusion body and includes a puncture needle, a catheter, a fixing clamp and a rubber pad; The puncture needle has an anti-detachment hook, which is located on one side of the puncture needle. The catheter is connected to the puncture needle and is located on one side of the puncture needle. The fixing clip is arranged on the outside of the catheter. The rubber pad is fixedly connected to the fixing clip and is located on one side of the fixing clip.

2. A transcardiac systemic perfusion machine according to claim 1, characterized in that: The fixing clip includes an elastic clip, a mounting ring, a snap buckle and a strap. The mounting ring is arranged on the outside of the catheter. The elastic clip is fixedly connected to the mounting ring and is located on the side of the mounting ring close to the puncture needle. The snap buckle is fixedly connected to the elastic clip and is located on one side of the elastic clip. The strap is fixedly connected to the mounting ring and is located on the side of the elastic clip away from the snap buckle.

3. A transcardiac systemic perfusion machine according to claim 1, characterized in that: The perfusion body includes a tank injection pump and a fixed base plate. The tank injection pump is communicated with the catheter and is located on the side of the catheter away from the puncture needle. The fixed base plate is fixedly connected to the tank injection pump and is located at the bottom of the tank injection pump.

4. A transcardiac systemic perfusion machine as claimed in claim 3, characterized in that: The fixed base plate includes a base plate, a pressure strip and a suction cup. The base plate is fixedly connected to the filling pump and is located at the bottom of the filling pump. The pressure strip is slidably connected to the base plate and is located on both sides of the base plate. The suction cup is fixedly connected to the pressure strip and is located at the bottom of the pressure strip.

5. A transcardiac systemic perfusion machine according to claim 4, characterized in that: The filling pump has a connector, which is located at one side of the filling pump; the pressure strip has a pull rod, which is located at the top of the pressure strip.

Images