Vacuum-pumping nitrogen-charging tamponade device and production line

Abstract

The utility model provides a vacuumizing, nitrogen charging and plug pressing device and a production line, and relates to the technical field of medical equipment.The vacuumizing, nitrogen charging and plug pressing device comprises a plug pressing air cylinder, a plug pressing shaft, a plug sucking base, a bottle cover, a valve body connecting base, a valve body and a pneumatic diaphragm valve set arranged on the valve body; according to the vacuumizing, nitrogen charging and plug pressing device, the design of an existing cam type distribution sliding ring is changed, and by means of the design that a multi-channel air channel and a pneumatic diaphragm valve set on the valve body are matched with the plug pressing air cylinder and the plug pressing shaft, the requirement for controlling the residual oxygen amount with the higher requirement in an infusion bottle is met, stability is kept, and the defective rate is reduced; the multi-channel gas path of the valve body and the pneumatic diaphragm valve group are designed in a combined manner, and the plug pressing nitrogen charging control mode is simplified while the two are modularly integrated; the whole device is convenient to maintain, meanwhile, the sanitation level is higher, the GMP requirement is met, and the in-place cleaning and in-place disinfection (CIP / SIP) requirement is met.

Description

Technical Field

[0001] The present application relates to the technical field of medical equipment, and in particular to a vacuum nitrogen filling and plugging device and a production line. Background Art

[0002] As a traditional form of infusion packaging, glass bottle infusions certainly have many disadvantages. For example, during clinical infusions, an air circuit must be formed to allow the drug to drip out, resulting in a high probability of secondary contamination. Glass bottles are large, take up space, and have high transportation costs. In addition, collisions during production and transportation can easily cause invisible cracks in the bottles, resulting in drug contamination and safety risks. However, glass bottles also have many advantages. For example, glass bottles have the most stable performance of all infusion packaging forms. They have excellent barrier properties such as water, oxygen, and light insulation, as well as antioxidant properties. They also have very stable compatibility with the drug solution. Therefore, many drugs on the market, especially nutritional solutions and therapeutic infusions (such as amino acids and fat emulsions), are packaged in glass bottles. These nutritional and therapeutic solutions have strict requirements on the oxygen content in the bottle. The residual oxygen content can significantly affect the shelf life of the drug solution. Therefore, controlling the residual oxygen content in each infusion bottle is a key performance requirement and technical indicator of the equipment. After filling, the infusion bottle needs to enter the vacuum, nitrogen filling and plugging station. During the vacuum, nitrogen filling and plugging process, the prior art CN105151381A discloses a vacuum, nitrogen filling and plugging device and production line. The plug suction seat sucks up the bottle cork through the plug suction shaft under the action of a lifting cam, and the cup sleeve descends through the outer shaft under the action of the lifting cam, so that the sealing cup cover is completely sealed and buckled on the bottle body and sealed with the shoulder of the bottle body, thereby forming a closed space between the cup sleeve and the bottle body. Then, the closed space is repeatedly vacuumed and nitrogen-filled through the nitrogen interface and the vacuum interface of vacuum and nitrogen filling until the residual oxygen content meets the requirements. Finally, the outer shaft remains stationary, and the plug suction shaft descends under the action of the lifting cam to press the bottle cork into the bottle mouth to complete the nitrogen filling and plugging work. During this working process, the plug removal vacuum is controlled by a mechanical distribution slip ring to control the presence or absence of vacuum. The main problems with existing vacuum nitrogen filling and plugging devices are: high mechanical sliding friction, high mechanical cam friction, easy falling off of debris to contaminate the medicine, and easy wear and tear that affects the seal and residual oxygen stability; the valve diameter is too small, the valve core is easily clogged, and the hygiene level is not ideal; there are many leakage points, resulting in insufficient oxygen replacement, and the residual oxygen content is difficult to control within 0.5% to meet higher residual oxygen control requirements.

[0003] Therefore, how to design a new type of vacuum nitrogen filling plugging device and production line has become the focus of research in the industry. Utility Model Content

[0004] In order to solve the above technical problems, the present application provides a vacuum nitrogen filling and plugging device, which changes the design of the existing cam-type distribution slip ring. With the help of the multi-channel air circuit, pneumatic diaphragm valve group and plugging cylinder and plugging shaft on the valve body, it is conducive to meeting the higher requirements for controlling the residual oxygen content in the infusion bottle and maintaining stability, thereby reducing the defective rate; the multi-channel air circuit and pneumatic diaphragm valve group of the valve body are combined in design, and the two are modularly integrated, while simplifying the plugging and nitrogen filling control method.

[0005] The technical solutions provided in this application are as follows:

[0006] A vacuum nitrogen filling plugging device, comprising: a plugging cylinder, a plugging shaft, a plug suction seat, a bottle cover, a valve body connecting seat, a valve body, and a pneumatic diaphragm valve group arranged on the valve body;

[0007] The pneumatic diaphragm valve assembly includes a vacuum pneumatic diaphragm valve unit and a nitrogen pneumatic diaphragm valve unit; the vacuum pneumatic diaphragm valve unit and the nitrogen pneumatic diaphragm valve unit are both mounted on a valve body, the valve body is provided with a vacuum main inlet and a nitrogen main inlet, and a vacuum channel and a nitrogen channel are provided inside the valve body; the vacuum channel connects the vacuum main inlet and the vacuum pneumatic diaphragm valve unit, and the nitrogen channel connects the nitrogen main inlet and the nitrogen pneumatic diaphragm valve unit; the upper end of the valve body connecting seat is connected to the bottom of the valve body, and the lower end of the valve body connecting seat is connected to the bottle cover;

[0008] The valve body is provided with an intermediate passage hole, a plugging cylinder is fixed to the top of the valve body, a plugging shaft is connected to the output piston of the plugging cylinder, the plugging shaft passes through the intermediate passage hole, and the plugging shaft forms a relatively sealed space between the valve body through the first seal and the second seal; the formed relatively sealed space is communicated with the vacuum main inlet through the vacuum channel, and is communicated with the nitrogen main inlet through the nitrogen channel;

[0009] The bottom end of the plug pressing shaft is connected with a plug suction seat, and the plug pressing shaft is provided with a central pipeline channel at the relatively sealed space formed, and the central pipeline channel directly leads to the plug suction seat for sucking and releasing the plug.

[0010] Furthermore, the vacuum pneumatic diaphragm valve unit includes a vacuum pneumatic diaphragm valve a and a vacuum pneumatic diaphragm valve b; the nitrogen pneumatic diaphragm valve unit includes a nitrogen pneumatic diaphragm valve a and a nitrogen pneumatic diaphragm valve b;

[0011] The vacuum channel includes a vacuum air path I, a vacuum air path of a vacuum pneumatic diaphragm valve a, and a vacuum air path I of a vacuum pneumatic diaphragm valve b, a vacuum air path II of a vacuum pneumatic diaphragm valve b, and a vacuum air path III of a vacuum pneumatic diaphragm valve b;

[0012] The nitrogen channel includes nitrogen gas path I, nitrogen gas path of nitrogen pneumatic diaphragm valve a, nitrogen gas path I of nitrogen pneumatic diaphragm valve b, and nitrogen gas path II of nitrogen diaphragm valve b;

[0013] The vacuum main inlet connects the vacuum pneumatic diaphragm valves a and b together through the vacuum air path I, and the nitrogen main inlet connects the nitrogen pneumatic diaphragm valves a and b together through the nitrogen air path I; the vacuum pneumatic diaphragm valve a communicates with the relatively sealed space formed by the central pressing plug shaft in the valve body through the vacuum air path of the vacuum pneumatic diaphragm valve a; the nitrogen pneumatic diaphragm valve a communicates with the relatively sealed space formed by the central pressing plug shaft in the valve body through the nitrogen air path of the nitrogen pneumatic diaphragm valve a.

[0014] The vacuum pneumatic diaphragm valve b is connected to the closed space between the bottle cover at the lower end of the valve body and the glass infusion bottle through the vacuum air path I, vacuum air path II and vacuum air path III of the vacuum pneumatic diaphragm valve b; the nitrogen pneumatic diaphragm valve b is connected to the closed space between the bottle cover at the lower end of the valve body and the glass infusion bottle through the nitrogen air path I and nitrogen air path II of the nitrogen pneumatic diaphragm valve b.

[0015] Furthermore, the valve body is also provided with a pressure sensor for monitoring vacuum and nitrogen pressure; the pressure sensor is connected to the vacuum air path II of the vacuum pneumatic diaphragm valve b for monitoring the vacuum pressure.

[0016] Furthermore, the pressure sensor is connected to the closed space between the bottle cover and the glass infusion bottle through the vacuum air path III of the vacuum pneumatic diaphragm valve b, and is used to monitor the nitrogen pressure.

[0017] Furthermore, a guide sleeve adapted to the plug shaft and a third seal of the plug shaft are provided in the valve body connecting seat, and the suction plug seat is fixedly connected to the plug shaft via a sealing ring.

[0018] Furthermore, a sealing cup sleeve that matches the shoulder and bottleneck of the infusion bottle is fixedly installed on the lower end of the bottle cover through a fixing ring.

[0019] Furthermore, a sealing ring is provided at the passage where the valve body connecting seat and the fixed connection portion of the valve body are located.

[0020] Furthermore, the vacuum nitrogen filling and plugging device of the present application also includes a glass infusion bottle lifting mechanism arranged below the bottle cover. The glass infusion bottle lifting mechanism is used to drive the glass infusion bottle to lift up through upward and downward movements so that the bottle shoulder and bottle neck contact the sealing cup sleeve and press tightly to form a seal, and to drive the glass infusion bottle downward to separate from the bottle cover.

[0021] The present application also provides a vacuum pumping, nitrogen filling and plugging production line, which includes the above-mentioned vacuum pumping, nitrogen filling and plugging device.

[0022] Beneficial effects

[0023] The present application provides a vacuum nitrogen filling plugging device, comprising: a plugging cylinder, a plugging shaft, a plug suction seat, a bottle cover, a valve body connecting seat, a valve body and a pneumatic diaphragm valve group arranged on the valve body; the vacuum nitrogen filling plugging device of the present application changes the design of the existing cam-type distribution slip ring, and uses the multi-channel air circuit on the valve body, the pneumatic diaphragm valve group and the plugging cylinder and the plugging shaft to cooperate with each other to meet the higher requirements for controlling the residual oxygen content in the infusion bottle and maintain stability, thereby reducing the defective rate; the multi-channel air circuit of the valve body and the pneumatic diaphragm valve group are combined in the design, and the modular integration of the two simplifies the plugging and nitrogen filling control method. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are only some embodiments recorded in this application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0025] Figure 1 A schematic diagram (three-dimensional) of the structure of a vacuum nitrogen filling plugging device is provided for this application;

[0026] Figure 2 for Figure 1 A top view of a vacuum nitrogen filling plugging device;

[0027] Figure 3 for Figure 2 Cross-sectional view at EE;

[0028] Figure 4 for Figure 1 A front view of a vacuum, nitrogen-filled plugging device;

[0029] Figure 5 for Figure 4 Cross-sectional view at AA in the middle;

[0030] Figure 6 for Figure 1 Schematic diagram of the structure of the middle valve body (3D);

[0031] Figure 7 for Figure 1 Schematic diagram of the gas path structure design of the middle valve body (3D); DETAILED DESCRIPTION

[0032] In order to help those skilled in the art better understand the technical solutions in this application, the technical solutions in the embodiments of this application will be clearly and completely described below. Obviously, the embodiments described are only part of the embodiments of this application, not all of the embodiments. Based on the embodiments in this application, all other embodiments obtained by those skilled in the art without making any creative efforts shall fall within the scope of protection of this application.

[0033] It should be noted that when an element is referred to as being “fixed on” or “set on” another element, it can be directly on the other element or indirectly set on the other element; when an element is referred to as being “connected to” another element, it can be directly connected to the other element or indirectly connected to the other element.

[0034] It should be understood that the terms "length", "width", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc., indicating the orientation or position relationship, are based on the orientation or position relationship shown in the accompanying drawings, and are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on this application.

[0035] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be understood to indicate or imply relative importance or implicitly specify the number of technical features indicated. Thus, a feature specified as "first" or "second" may explicitly or implicitly include one or more of such features. Throughout the description of this application, "plurality" or "several" means two or more, unless otherwise specifically defined.

[0036] It should be noted that the structures, proportions, sizes, etc. illustrated in the drawings of this specification are only used to match the contents disclosed in the specification for people familiar with this technology to understand and read, and are not used to limit the conditions under which this application can be implemented. Therefore, they have no substantive technical significance. Any structural modification, change in proportional relationship or adjustment of size should still fall within the scope of the technical content disclosed in this application without affecting the efficacy and purpose that can be achieved by this application.

[0037] The embodiments of the present application are written in a progressive manner.

[0038] The present application provides a vacuum nitrogen filling plugging device, comprising: a plugging cylinder, a plugging shaft, a plug suction seat, a bottle cover, a valve body connecting seat, a valve body, and a pneumatic diaphragm valve group arranged on the valve body;

[0039] The pneumatic diaphragm valve assembly includes a vacuum pneumatic diaphragm valve unit and a nitrogen pneumatic diaphragm valve unit; the vacuum pneumatic diaphragm valve unit and the nitrogen pneumatic diaphragm valve unit are both mounted on a valve body, the valve body is provided with a vacuum main inlet and a nitrogen main inlet, and a vacuum channel and a nitrogen channel are provided inside the valve body; the vacuum channel connects the vacuum main inlet and the vacuum pneumatic diaphragm valve unit, and the nitrogen channel connects the nitrogen main inlet and the nitrogen pneumatic diaphragm valve unit; the upper end of the valve body connecting seat is connected to the bottom of the valve body, and the lower end of the valve body connecting seat is connected to the bottle cover;

[0040] The valve body is provided with an intermediate passage hole, a plugging cylinder is fixed to the top of the valve body, a plugging shaft is connected to the output piston of the plugging cylinder, the plugging shaft passes through the intermediate passage hole, and the plugging shaft forms a relatively sealed space between the valve body through the first seal and the second seal; the formed relatively sealed space is communicated with the vacuum main inlet through the vacuum channel, and is communicated with the nitrogen main inlet through the nitrogen channel;

[0041] The bottom end of the plug pressing shaft is connected with a plug suction seat, and the plug pressing shaft is provided with a central pipeline channel at the relatively sealed space formed, and the central pipeline channel directly leads to the plug suction seat for sucking and releasing the plug.

[0042] The vacuum nitrogen filling and plugging device of the present application changes the design of the existing cam-type distribution slip ring. With the help of the multi-channel air circuit on the valve body, the pneumatic diaphragm valve group and the plugging cylinder and the plugging shaft, it is conducive to meeting the higher requirements for controlling the residual oxygen content in the infusion bottle and maintaining stability, thereby reducing the defective rate; the multi-channel air circuit of the valve body and the pneumatic diaphragm valve group are combined in the modular integration of the two, and the plugging and nitrogen filling control method is simplified.

[0043] See also Figure 1-7The valve body of the present application is primarily provided with a vacuum main inlet, a nitrogen main inlet, vacuum pneumatic diaphragm valves a and b, and nitrogen pneumatic diaphragm valves a and b. The vacuum main inlet connects vacuum pneumatic diaphragm valves a and b via vacuum air path I, while the nitrogen main inlet similarly connects nitrogen pneumatic diaphragm valves a and b via nitrogen air path I. Similarly, vacuum pneumatic diaphragm valve a communicates with the relatively sealed space formed by the central plugging shaft of the valve body via the vacuum air path of vacuum pneumatic diaphragm valve a, facilitating the subsequent vacuum plug suction during operation. Nitrogen pneumatic diaphragm valve a communicates with the relatively sealed space formed by the central plugging shaft of the valve body via the nitrogen air path of nitrogen pneumatic diaphragm valve a, facilitating the subsequent vacuum break after plugging to prevent the plug from being sucked out of the glass bottle. Similarly, the vacuum pneumatic diaphragm valve b is connected to the enclosed space between the bottle cover at the lower end of the valve body and the glass infusion bottle through the vacuum air path I, vacuum air path II and vacuum air path III of the vacuum pneumatic diaphragm valve b, so that the enclosed space between the bottle cover and the glass infusion bottle can be evacuated during subsequent operation; the nitrogen pneumatic diaphragm valve b is connected to the enclosed space between the bottle cover at the lower end of the valve body and the glass infusion bottle through the nitrogen air path I and nitrogen air path II of the nitrogen pneumatic diaphragm valve b, so that the enclosed space between the bottle cover and the glass infusion bottle can be replenished with nitrogen during subsequent operation; further, in order to monitor the vacuum and nitrogen pressure in real time, a pressure sensor connection port is provided below the vacuum and nitrogen pneumatic diaphragm valve of the valve body, which can be externally connected to a suitable sanitary-grade pressure sensor, and the provided pressure sensor is connected to the vacuum through the vacuum air path II of the vacuum pneumatic diaphragm valve b for monitoring the vacuum pressure. The vacuum air path III through the vacuum pneumatic diaphragm valve b is connected to the closed space between the bottle cover and the glass infusion bottle and is used for monitoring the nitrogen pressure.

[0044] The unique multi-channel air path and pneumatic diaphragm valve group design of the valve body of this application can not only meet the control needs of multiple channels and multiple media, but also enable its intensive design to simplify the original structure, save installation space, simplify the pipeline connection and control line routing layout, facilitate maintenance, and have a higher hygiene level and comply with GMP requirements, meeting the requirements of cleaning in place and sterilization in place (CIP / SIP).

[0045] The plunger cylinder is secured to the top of the multi-channel pneumatic diaphragm valve control valve body (valve body). The plunger shaft is connected to the plunger cylinder output piston and passes through the middle channel of the multi-channel pneumatic diaphragm valve control valve body. The plunger shaft forms a relatively sealed space with the multi-channel pneumatic diaphragm valve control valve body via the plunger shaft's first and second seals. This relatively sealed space communicates with the vacuum and nitrogen main inlets via the vacuum air path of the vacuum pneumatic diaphragm valve and the nitrogen air path of the nitrogen pneumatic diaphragm valve. Furthermore, the plunger shaft is provided with a central pipeline channel within the relatively sealed space formed. This central pipeline channel directly connects to the plug suction seat for plug suction and release. Preferably, the plug suction seat is directly and fixedly connected to the plunger shaft via a sealing ring.

[0046] The upper end of the valve body connector is fixedly connected to the control valve body of the multi-channel pneumatic diaphragm valve, while the lower end of the valve body connector is fixedly connected to the bottle cover via a clamp. To ensure the coaxiality of the plunger shaft during operation, a guide sleeve compatible with the plunger shaft and a third seal for the plunger shaft are provided in the valve body connector. It is understood that those skilled in the art can refer to existing technologies for the design of the first, second, and third seals.

[0047] A sealing cup sleeve with good sealing performance that matches the shoulder and bottleneck of the glass infusion bottle is fixedly installed under the bottle cover through a fixing ring. The sealing cup sleeve is made of relatively soft and elastic silicone or rubber material, and the shape and curvature of the cup sleeve are adapted to the model, specification and size of the glass infusion bottle.

[0048] In order to ensure the sealing of the through channel with the pressure sensor, a sealing ring is provided at the channel during the fixed connection between the valve body connecting seat and the multi-channel pneumatic diaphragm valve control valve body to prevent air leakage.

[0049] The working process of a vacuum nitrogen filling and plugging device: the filled glass infusion bottle is transported to the bottom of the vacuum nitrogen filling and plugging device through a conveying mechanism, the plug removing and plugging cylinder is extended first, and at the same time, the vacuum pneumatic diaphragm valve a is opened, and after the plug suction seat sucks the butyl rubber plug through vacuum, the plug removing and plugging cylinder is retracted, and the vacuum pneumatic diaphragm valve a is kept open; then the glass infusion bottle lifting mechanism (at this time in the lower position) lifts the infusion bottle to be vacuum nitrogen filled and plugged, so that the shoulder and neck of the glass bottle contact the sealing cup sleeve in the device and press it tightly to form a seal. At this time, there is a certain gap between the sucked butyl rubber plug and the upper end of the bottle mouth of the glass infusion bottle, so that the gas in the infusion bottle to be vacuum nitrogen filled and plugged can be replaced; then the vacuum pneumatic diaphragm valve Valve b opens, extracting air from the bottle. After a set time, vacuum pneumatic diaphragm valve b closes. Then, nitrogen pneumatic diaphragm valve b opens, filling the infusion bottle to be evacuated, nitrogen-filled, and plugged. It closes after a set time. Vacuum pneumatic diaphragm valve b and nitrogen pneumatic diaphragm valve b alternate multiple times (e.g., 3-5 times) according to the program setting to ensure the desired residual oxygen content in the infusion bottle. Finally, the stopper removal and plugging cylinder extends again, driving the stopper suction seat downward, pressing the butyl rubber stopper into the bottle opening, completing the bottle seal. Simultaneously, vacuum pneumatic diaphragm valve a closes and nitrogen pneumatic diaphragm valve a opens. This is done by using positive pressure to break the stopper suction vacuum and prevent residual vacuum from pulling the butyl stopper out of the bottle opening. After plugging, the stopper removal and plugging cylinder retracts to its initial position. Simultaneously, the infusion bottle lifting mechanism descends, driving the bottle out of the sealing sleeve and back to its initial entry position. The entire process of vacuum evacuation, nitrogen filling, and plugging is now complete.

[0050] It can be understood that the glass infusion bottle lifting mechanism of the present application is an existing manipulator device or a lifting platform, etc.

[0051] It should be noted that Figure 4 and Figure 5 The structural design of the components in the vacuum nitrogen filling plugging device shown includes:

[0052] 1. Plug cylinder, 2. Valve body, 3. Pneumatic control head, 4. Pressure sensor, 5. Plug shaft, 6. First seal, 7. Second seal, 8. Guide sleeve, 9. Third seal, 10. Suction plug seat, 11. Valve body connecting seat, 12. Sealing ring, 13. Clamp, 14. Bottle cover, 15. Fixing ring, 16. Sealing cup sleeve, 17. Infusion bottle stopper, 18. Glass infusion bottle, 19. Sealing ring.

[0053] Figure 7The structural design of the valve body shown includes: 1. vacuum main inlet, 2. nitrogen main inlet, 3. vacuum pneumatic diaphragm valve a, 4. vacuum pneumatic diaphragm valve b, 5. nitrogen pneumatic diaphragm valve a, 6. nitrogen pneumatic diaphragm valve b, 7. pressure sensor, 8. vacuum air path I, 9. nitrogen air path I, 10. vacuum pneumatic diaphragm valve a vacuum air path, 11. nitrogen pneumatic diaphragm valve a nitrogen air path, 12. vacuum pneumatic diaphragm valve b vacuum air path I, 13. nitrogen pneumatic diaphragm valve b nitrogen air path I, 14. vacuum pneumatic diaphragm valve b vacuum air path II, 15. vacuum pneumatic diaphragm valve b vacuum air path III, 16. nitrogen pneumatic diaphragm valve b nitrogen air path II.

[0054] The present application also provides a vacuum nitrogen filling and plugging production line, including the vacuum nitrogen filling and plugging device described above. The beneficial effects of the vacuum nitrogen filling and plugging production line of the present application correspond to the beneficial effects of the vacuum nitrogen filling and plugging device described above, and will not be repeated.

[0055] The above description of the disclosed embodiments is intended to enable one skilled in the art to implement or use the present application. Various modifications to these embodiments will be readily apparent to one skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the present application. Therefore, the present application is not limited to the embodiments shown herein, but is intended to conform to the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A vacuum nitrogen filling plugging device, characterized in that: include: A plug pressing cylinder, a plug pressing shaft, a plug suction seat, a bottle cover, a valve body connecting seat, a valve body, and a pneumatic diaphragm valve group arranged on the valve body; The pneumatic diaphragm valve assembly includes a vacuum pneumatic diaphragm valve unit and a nitrogen pneumatic diaphragm valve unit; the vacuum pneumatic diaphragm valve unit and the nitrogen pneumatic diaphragm valve unit are both mounted on a valve body, the valve body is provided with a vacuum main inlet and a nitrogen main inlet, and a vacuum channel and a nitrogen channel are provided inside the valve body; the vacuum channel connects the vacuum main inlet and the vacuum pneumatic diaphragm valve unit, and the nitrogen channel connects the nitrogen main inlet and the nitrogen pneumatic diaphragm valve unit; the upper end of the valve body connecting seat is connected to the bottom of the valve body, and the lower end of the valve body connecting seat is connected to the bottle cover; The valve body is provided with an intermediate passage hole, a plugging cylinder is fixed to the top of the valve body, a plugging shaft is connected to the output piston of the plugging cylinder, the plugging shaft passes through the intermediate passage hole, and the plugging shaft forms a relatively sealed space between the valve body through the first seal and the second seal; the formed relatively sealed space is communicated with the vacuum main inlet through the vacuum channel, and is communicated with the nitrogen main inlet through the nitrogen channel; The bottom end of the plug pressing shaft is connected with a plug suction seat, and the plug pressing shaft is provided with a central pipeline channel at the relatively sealed space formed, and the central pipeline channel directly leads to the plug suction seat for sucking and releasing the plug.

2. The device according to claim 1, characterized in that The vacuum pneumatic diaphragm valve unit includes a vacuum pneumatic diaphragm valve a and a vacuum pneumatic diaphragm valve b; the nitrogen pneumatic diaphragm valve unit includes a nitrogen pneumatic diaphragm valve a and a nitrogen pneumatic diaphragm valve b; The vacuum channel includes a vacuum air path I, a vacuum air path of a vacuum pneumatic diaphragm valve a, and a vacuum air path I of a vacuum pneumatic diaphragm valve b, a vacuum air path II of a vacuum pneumatic diaphragm valve b, and a vacuum air path III of a vacuum pneumatic diaphragm valve b; The nitrogen channel includes nitrogen gas path I, nitrogen gas path of nitrogen pneumatic diaphragm valve a, nitrogen gas path I of nitrogen pneumatic diaphragm valve b, and nitrogen gas path II of nitrogen diaphragm valve b; The vacuum main inlet connects the vacuum pneumatic diaphragm valves a and b together through the vacuum air path I, and the nitrogen main inlet connects the nitrogen pneumatic diaphragm valves a and b together through the nitrogen air path I; the vacuum pneumatic diaphragm valve a communicates with the relatively sealed space formed by the central pressing plug shaft in the valve body through the vacuum air path of the vacuum pneumatic diaphragm valve a; the nitrogen pneumatic diaphragm valve a communicates with the relatively sealed space formed by the central pressing plug shaft in the valve body through the nitrogen air path of the nitrogen pneumatic diaphragm valve a. The vacuum pneumatic diaphragm valve b is connected to the closed space between the bottle cover at the lower end of the valve body and the glass infusion bottle through the vacuum air path I, vacuum air path II and vacuum air path III of the vacuum pneumatic diaphragm valve b; the nitrogen pneumatic diaphragm valve b is connected to the closed space between the bottle cover at the lower end of the valve body and the glass infusion bottle through the nitrogen air path I and nitrogen air path II of the nitrogen pneumatic diaphragm valve b.

3. The device according to claim 2, characterized in that The valve body is also provided with a pressure sensor for monitoring vacuum and nitrogen pressure; the pressure sensor is connected to the vacuum air path II of the vacuum pneumatic diaphragm valve b for monitoring the vacuum pressure.

4. The device according to claim 3, characterized in that The pressure sensor is connected to the closed space between the bottle cover and the glass infusion bottle through the vacuum air path III of the vacuum pneumatic diaphragm valve b and is used to monitor the nitrogen pressure.

5. The device according to claim 2, characterized in that A guide sleeve matched with the plug-pressing shaft and a third sealing member of the plug-pressing shaft are provided in the valve body connecting seat, and the suction plug seat is fixedly connected to the plug-pressing shaft through a sealing ring.

6. The device according to claim 2, characterized in that The lower end of the bottle cover is fixedly mounted with a sealing cup sleeve which matches the bottle shoulder and bottleneck of the infusion bottle through a fixing ring.

7. The device according to claim 2, characterized in that A sealing ring is provided at the passage where the valve body connecting seat and the valve body fixed connection part are located.

8. The device according to any one of claims 1 to 7, characterized in that: It also includes a glass infusion bottle lifting mechanism arranged below the bottle cover. The glass infusion bottle lifting mechanism moves upward and downward to drive the glass infusion bottle to lift so that the bottle shoulder and bottle neck contact the sealing cup sleeve and press tightly to form a seal, and to drive the glass infusion bottle downward to separate from the bottle cover.

9. A vacuum nitrogen filling plugging production line, characterized in that: The invention comprises the vacuum nitrogen filling plugging device as described in any one of claims 1 to 8.

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