Device for grinding molecular biology sample

By designing a multi-stage crushing and grinding device, the problem of low efficiency of the existing device is solved, efficient grinding and fine powder processing of block samples are achieved, and the operation process is simplified.

CN223367105UActive Publication Date: 2025-09-23FOURTH MILITARY MEDICAL UNIVERSITY
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Patent Information

Application Number
CN202422400626.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-09-30
Publication Date
2025-09-23
Estimated Expiration
2034-09-30

AI Technical Summary

Technical Problem

Existing devices are inefficient in grinding molecular biology samples and require multiple operations, which easily causes sample spillage and makes it difficult to efficiently process bulk samples.

Method used

A device is designed, which includes a wall breaking chamber, a crushing chamber and a grinding chamber, and is equipped with a wall breaker, a crusher and a grinder respectively. The motor drives the blade, the crushing cylinder and the grinding block to perform multi-stage crushing and grinding to achieve continuous processing of samples.

Benefits of technology

It achieves efficient grinding of bulk samples, improves grinding efficiency, makes the powder finer, simplifies operation, and reduces the risk of sample spillage.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model aims to provide a device for grinding molecular biology samples, and relates to the technical field of sample inspection, a wall breaking bin, a crushing bin, a grinding bin and a collecting bin are sequentially arranged in a shell from top to bottom, when the device is used, a blocky sample is placed in the wall breaking bin, a wall breaking machine is installed, the wall breaking machine is controlled by a control panel to crush the blocky sample, and then the blocky sample is ground. A blocking plate below the wall breaking bin is controlled to be opened in a sliding mode through an electric push rod, so that the crushed sample falls into a crushing bin, the sample is further crushed through a crushing cylinder, the crushed sample falls into a grinding base below, a grinding motor drives a grinding block to rotate to grind the sample, and the diameter of sample particles is further reduced; the ground sample directly falls into a collecting box of the collecting bin, so that the sample is convenient to collect; by means of the structure, blocky samples can be directly ground, the grinding efficiency is improved, ground powder is finer, and operation is convenient.
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Description

Technical Field

[0001] The utility model relates to the technical field related to sample testing, and in particular to a device for grinding molecular biology samples. Background Art

[0002] Molecular biology is a discipline that studies the relationships and interactions between biological macromolecules, which mainly refer to two major categories: genes and proteins. Molecular biology is based on disciplines such as genetics, biochemistry, and cell biology, and studies various life phenomena of organisms at the molecular level.

[0003] In hospital laboratories, biological samples often need to be ground into powder or fine particles for testing and analysis. However, the grinding efficiency of current clinical devices is low.

[0004] The prior art CN215843180U discloses a molecular biology sample grinding device for medical laboratory. The grinding roller of the device is prone to sticking residual samples, which is not conducive to collecting sample powder. In addition, the device can only grind samples after preliminary crushing. However, most clinical samples are in block form. When using the device, another device is required to crush the block samples before use. The sample needs to be poured back and forth and two devices need to be operated, which is cumbersome, the sample is easily spilled, and the grinding efficiency is low. Utility Model Content

[0005] In view of the shortcomings of the existing technology, the present invention provides the following technical solutions:

[0006] A device for grinding molecular biological samples comprises a housing, wherein a wall breaking chamber, a crushing chamber, a grinding chamber, and a collection chamber are sequentially provided in the housing from top to bottom. The wall breaking chamber is open at the top and communicates with the crushing chamber at the bottom. The crushing chamber is communicated with the grinding chamber at the bottom, and the grinding chamber is communicated with the collection chamber at the bottom. The wall breaking chamber, crushing chamber, and grinding chamber are respectively provided with a wall breaking machine, a crusher, and a grinder.

[0007] The crusher includes two symmetrically and closely arranged crushing cylinders, one crushing cylinder is provided with a plurality of annular grooves, and the other crushing cylinder is fixed with a plurality of annular protrusions, which are tightly matched with the annular grooves. An upper scraper and a lower scraper are respectively provided above and below the crushing cylinder, and both ends of the upper scraper and the lower scraper are fixedly connected to the inner wall of the crushing bin.

[0008] Furthermore, the wall breaking machine can be detachably installed in the wall breaking bin. The wall breaking machine includes a connecting cover, a wall breaking motor, a mounting rod and a blade. The connecting cover is threadedly connected to the top of the wall breaking bin, the wall breaking motor is fixedly installed on the connecting cover, the mounting rod is fixedly installed on the drive shaft of the wall breaking motor, and the blade is fixedly installed on the mounting rod. The mounting rod is driven to rotate by the wall breaking motor, thereby driving the blade to rotate.

[0009] Furthermore, the crushing cylinder is rotatably installed in the crushing bin, and two crushing motors are fixedly arranged in the shell corresponding to the two crushing cylinders. One end of the crushing cylinder is fixedly connected to the driving shaft of the crushing motor, and the crushing cylinder is driven to rotate by the crushing motor.

[0010] Furthermore, the grinding machine includes a grinding seat, a grinding block and a grinding motor. The grinding seat is fixedly installed in the grinding chamber, the grinding block is movably installed above the grinding seat and is loosely fitted with the grinding seat. The grinding motor is fixedly installed on the shell and drives the grinding block to rotate through the grinding motor.

[0011] Furthermore, a plurality of grooves are provided on the mating surfaces of the grinding block and the grinding seat.

[0012] Furthermore, a collection box is installed in the collection bin in a sliding drawer-like manner.

[0013] Furthermore, a sealing plate is slidably arranged below the wall breaking bin, and an electric push rod is fixedly arranged in the shell, and the electric push rod drives the sealing plate to slide and block the bottom of the wall breaking bin or open the bottom of the wall breaking bin.

[0014] Furthermore, structures that fit into the annular groove and the annular protrusion are provided on the surfaces of the upper scraper and the lower scraper that fit into the crushing cylinder, and the two upper scrapers form a structure that is wide at the top and narrow at the bottom.

[0015] Furthermore, a collecting bucket is fixedly arranged below the crushing bin.

[0016] Furthermore, a mounting frame is fixedly provided on the inner wall of the grinding chamber, the grinding block is rotatably mounted on the mounting frame, the grinding motor is mounted on the mounting frame, a gear set is provided in the mounting frame, and the grinding motor and the grinding block are connected through the gear set.

[0017] Furthermore, a power supply is fixedly arranged in the shell, and a control panel is arranged above the shell.

[0018] Compared with the existing technology, the technical solution of this application has the following beneficial effects:

[0019] The utility model has a wall breaking bin, a crushing bin, a grinding bin and a collecting bin in sequence from top to bottom in a shell. When in use, a block sample is placed in the wall breaking bin, a wall breaking machine is installed, the wall breaking machine is controlled by a control panel to crush the block sample, and then the blocking plate below the wall breaking bin is controlled to slide open by an electric push rod, so that the crushed sample falls into the crushing bin, the sample is further crushed by the crushing cylinder, and the crushed sample falls into the grinding seat below, and the grinding block is driven by a grinding motor to rotate and grind the sample, thereby further reducing the diameter of the sample particles. The ground sample directly falls into the collecting box of the collecting bin for easy collection. The block sample can be directly ground, thereby improving the grinding efficiency, making the ground powder finer and easy to operate. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 This is a schematic diagram of the three-dimensional structure of the utility model;

[0021] Figure 2 This is a schematic diagram of the front view structure section of the utility model;

[0022] Figure 3 This is an enlarged schematic diagram of the front view structural section A of the present invention;

[0023] Figure 4 This is an enlarged schematic diagram of the front view structural section B of the present invention;

[0024] Figure 5 This is a schematic side view of the structure of the utility model;

[0025] Figure 6 This is a schematic cross-sectional view of the upper portion of the crushing bin of the present invention;

[0026] Figure 7 It is an enlarged schematic diagram of the cross section C above the crushing bin of the present invention.

[0027] In the figure: shell -1, wall breaking chamber -101, sealing plate -1011, crushing chamber -102, collecting bucket -1021, grinding chamber -103, mounting frame -1031, collecting chamber -104, collecting box -2, control panel -3, wall breaking machine -4, connecting cover -401, wall breaking motor -402, mounting rod -403, blade -404, power supply -5, electric push rod -6, grinding seat -7, grinding block -8, gear set -9, grinding motor -10, crushing cylinder -11, crushing motor -12, upper scraper -13, lower scraper -14. DETAILED DESCRIPTION

[0028] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention. Example 1

[0029] See also Figure 1-7 A device for grinding molecular biological samples comprises a shell 1, in which a wall breaking chamber 101, a crushing chamber 102, a grinding chamber 103, and a collecting chamber 104 are sequentially provided from top to bottom. The wall breaking chamber 101 is open at the top and communicates with the crushing chamber 102 at the bottom. The crushing chamber 102 is communicated with the grinding chamber 103 at the bottom, and the grinding chamber 103 is communicated with the collecting chamber 104 at the bottom. The wall breaking chamber 101, the crushing chamber 102, and the grinding chamber 103 are respectively provided with a wall breaking machine 4, a crusher, and a grinder.

[0030] In this embodiment, the wall breaking machine 4 is detachably mounted in the wall breaking bin 101. The wall breaking machine 4 includes a connecting cover 401, a wall breaking motor 402, a mounting rod 403 and a blade 404. The connecting cover 401 is threadedly connected to the top of the wall breaking bin 101. The wall breaking motor 402 is fixedly mounted on the connecting cover 401. The mounting rod 403 is fixedly mounted on the driving shaft of the wall breaking motor 402. The blade 404 is fixedly mounted on the mounting rod 403. The wall breaking motor 402 drives the mounting rod 403 to rotate, thereby driving the blade 404 to rotate, thereby crushing the block sample in the wall breaking bin 101 to facilitate the next step of crushing.

[0031] In this embodiment, a sealing plate 1011 is slidably arranged under the wall breaking bin 101, and an electric push rod 6 is fixedly arranged in the shell 1, and the electric push rod 6 drives the sealing plate 1011 to slide and block the bottom of the wall breaking bin 101 or open the bottom of the wall breaking bin 101. Example 2

[0032] See also Figure 1-7According to embodiment 1, the crusher includes two symmetrically and closely arranged crushing cylinders 11, one crushing cylinder 11 is provided with a plurality of annular grooves, and the other crushing cylinder 11 is fixedly provided with a plurality of annular protrusions, which are tightly matched with the annular grooves, and an upper scraper 13 and a lower scraper 14 are respectively provided above and below the crushing cylinder 11, and both ends of the upper scraper 13 and the lower scraper 14 are fixedly connected to the inner wall of the crushing bin 102; the crushing cylinder 11 is rotatably installed in the crushing bin 102, and two crushing motors 12 are fixedly provided in the shell 1 corresponding to the two crushing cylinders 11, one end of the crushing cylinder 11 is fixedly connected to the driving shaft of the crushing motor 12, and is driven by the crushing motor 12; the two crushing cylinders 11 rotate in opposite directions to crush the sample falling from the wall-breaking bin 101;

[0033] In this embodiment, in order to ensure the crushing effect, a plurality of annular grooves are provided on one crushing cylinder 11, and a plurality of annular protrusions are fixedly provided on the other crushing cylinder 11. The cooperation between the annular protrusions and the annular grooves can effectively squeeze the sample and improve the crushing effect.

[0034] In this embodiment, referring to the prior art CN215843180U, the sample falling from above cannot fall well into the junction of the two crushing cylinders 11, so the two upper scrapers 13 are installed into a structure that is wide at the top and narrow at the bottom, which can well collect the sample falling into the junction of the two crushing cylinders 11, and in order to scrape off the sample powder on the crushing cylinder 11, an upper scraper 13 and a lower scraper 14 are respectively provided above and below the crushing cylinder 11, which can scrape off the sample on the crushing cylinder 11. Example 3

[0035] See also Figure 1-7 According to embodiment 1, the grinder includes a grinding seat 7, a grinding block 8 and a grinding motor 10, the grinding seat 7 is fixedly installed in the grinding chamber 103, the grinding block 8 is movably installed above the grinding seat 7, and is clearance-matched with the grinding seat 7, the grinding motor 10 is fixedly installed on the housing 1, a collecting bucket 1021 is fixedly provided below the crushing chamber 102, a mounting frame 1031 is fixedly provided on the inner wall of the grinding chamber 103, the grinding block 8 is rotatably mounted on the mounting frame 1031, the grinding motor 10 is mounted on the mounting frame 1031, a gear set 9 is provided in the mounting frame 1031, the grinding motor 10 and the grinding block 8 are connected through the gear set 9, the gear set 9 is composed of two spur gears, and the grinding block 8 is driven to rotate by the grinding motor 10;

[0036] In this embodiment, a plurality of grooves are provided on the mating surfaces of the grinding block 8 and the grinding seat 7 so that the crushed sample can better fall into the gap between the grinding seat 7 and the grinding block 8. A collection box 2 is installed in the collection bin 104 in a sliding drawer-like manner, which can directly collect the ground sample.

[0037] The preferred embodiments of the present invention disclosed above are intended only to help illustrate the present invention. The preferred embodiments do not describe all details in detail, nor do they limit the present invention to the specific embodiments described. Obviously, many modifications and variations are possible based on the contents of this specification. These embodiments are selected and described in detail in this specification to better explain the principles and practical applications of the present invention, thereby enabling those skilled in the art to better understand and utilize the present invention. The present invention is limited only by the claims and their full scope and equivalents.

Claims

1. A device for grinding molecular biological samples, comprising a housing, characterized in that: The shell is provided with a wall breaking bin, a crushing bin, a grinding bin and a collecting bin from top to bottom in sequence. A collecting box is installed in a sliding drawer-like manner in the collecting bin. The top of the wall breaking bin is open and is connected to the crushing bin at the bottom. The bottom of the crushing bin is connected to the grinding bin, and the bottom of the grinding bin is connected to the collecting bin. The wall breaking bin, crushing bin and grinding bin are respectively provided with a wall breaking machine, a crusher and a grinder. The crusher includes two symmetrically and closely arranged crushing cylinders, one crushing cylinder is provided with a plurality of annular grooves, and the other crushing cylinder is fixed with a plurality of annular protrusions, which are tightly matched with the annular grooves. An upper scraper and a lower scraper are respectively provided above and below the crushing cylinder, and both ends of the upper scraper and the lower scraper are fixedly connected to the inner wall of the crushing bin.

2. The device for grinding molecular biology samples according to claim 1, characterized in that: The wall breaker can be detachably installed in the wall breaking bin. The wall breaker includes a connecting cover, a wall breaking motor, a mounting rod and a blade. The connecting cover is threadedly connected to the top of the wall breaking bin. The wall breaking motor is fixedly installed on the connecting cover. The mounting rod is fixedly installed on the driving shaft of the wall breaking motor. The blade is fixedly installed on the mounting rod. The mounting rod is driven to rotate by the wall breaking motor, thereby driving the blade to rotate.

3. The device for grinding molecular biological samples according to claim 1, characterized in that: The crushing cylinder is rotatably mounted in the crushing bin, and two crushing motors are fixedly arranged in the shell corresponding to the two crushing cylinders. One end of the crushing cylinder is fixedly connected to the driving shaft of the crushing motor, and the crushing cylinder is driven to rotate by the crushing motor.

4. The device for grinding molecular biology samples according to claim 1, characterized in that: The grinding machine includes a grinding seat, a grinding block and a grinding motor. The grinding seat is fixedly installed in the grinding chamber, the grinding block is movably installed above the grinding seat and is loosely fitted with the grinding seat. The grinding motor is fixedly installed on the housing and drives the grinding block to rotate.

5. The device for grinding molecular biology samples according to claim 4, characterized in that: A plurality of grooves are provided on the matching surfaces of the grinding block and the grinding seat.

6. The device for grinding molecular biology samples according to claim 1, characterized in that: A sealing plate is slidably arranged below the wall breaking bin, and an electric push rod is fixedly arranged in the shell, and the sealing plate is driven by the electric push rod to slide and block the bottom of the wall breaking bin or open the bottom of the wall breaking bin.

7. The device for grinding molecular biology samples according to claim 1, characterized in that: The surfaces of the upper scraper and the lower scraper that are in contact with the crushing cylinder are provided with structures that are in contact with the annular groove and the annular protrusion, and the two upper scrapers form a structure that is wide at the top and narrow at the bottom.

8. The device for grinding molecular biology samples according to claim 4, characterized in that: A mounting frame is fixedly provided on the inner wall of the grinding chamber, the grinding block is rotatably mounted on the mounting frame, the grinding motor is mounted on the mounting frame, a gear set is provided in the mounting frame, and the grinding motor and the grinding block are connected via the gear set.

9. The device for grinding molecular biology samples according to claim 1, characterized in that: A power supply is fixedly arranged in the shell, and a control panel is arranged above the shell.

Citation Information

Patent Citations

  • Medical molecular biology sample grinding device for clinical laboratory

    CN215843180U