Slide staining device for pathological histological special staining and medical and health clinical inspection equipment
By designing a staining device consisting of a substrate and a container tube, the problems of reagent waste and contamination in special staining of pathological tissues have been solved, achieving the effects of cost saving and improved experimental accuracy.
Patent Information
- Application Number
- CN202422013309.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-08-16
- Publication Date
- 2025-09-23
- Estimated Expiration
- 2034-08-16
AI Technical Summary
In the current technology, the special staining process for pathological tissues results in serious reagent waste, high cost and significant pollution, and the lack of specialized staining equipment leads to a high risk of specimen drying out.
Design a staining device including a substrate and a receiving tube. The substrate has protrusions forming a holding area in which the glass slide is held. The receiving tube has a receiving cavity for holding pathological tissue blocks. Staining reagent is added only to the receiving tube. Combined with the design of a cover and a sealing ring, reagent waste and specimen drying are prevented.
It effectively reduces reagent waste, lowers costs, improves staining efficiency, ensures specimen moisture, reduces the risk of contamination, and improves experimental accuracy.
Smart Images

Figure CN223377031U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of medical treatment, in particular to a slide staining device for special staining of pathological histology and medical and sanitary clinical testing equipment. Background Art
[0002] Special staining is a fundamental technique in histopathological staining. During the dripping process and waterbath incubation, it is crucial to ensure that the special stain completely and adequately covers the histological specimen to prevent it from drying out. Currently, there are no dedicated staining devices specifically for histopathological special stains. Conventional staining jars are typically used to add the staining reagent and then immerse the slide directly in the jars. This results in reagent waste, increased costs, and increased hazardous liquid discharge. Utility Model Content
[0003] The main purpose of the utility model is to propose a staining device for special staining of pathological histology and a medical and hygienic clinical testing equipment, aiming to provide a staining device for special staining of pathological histology and a medical and hygienic clinical testing equipment that reduces reagent waste, saves costs and is low in pollution.
[0004] To achieve the above-mentioned purpose, the staining device for special staining of pathological histology proposed in the present invention comprises:
[0005] A substrate is provided with two protrusions arranged in pairs, a holding interval is formed between the two protrusions, and the slide is held in the holding interval; and
[0006] The accommodating tube is cylindrical and has an accommodating cavity therein for accommodating the pathological tissue block; one end of the accommodating tube is horizontally protruded with a holding arm for holding the two protrusions and covering the slide.
[0007] In one embodiment, the two protrusions, the glass slide, and the accommodating tube are configured as an observation group, and two observation groups are provided and spaced apart on the substrate.
[0008] In one embodiment, the substrate is made of hard plastic.
[0009] In one embodiment, a counterweight is installed on the lower end surface of the substrate to allow the substrate to sink into the water bath.
[0010] In one embodiment, a silicone barrier layer is provided around the side wall of the accommodating cavity.
[0011] In one embodiment, the accommodating tube is further provided with a cover for closing the accommodating cavity.
[0012] In one embodiment, the cover body is further provided with an operating portion for holding.
[0013] In one embodiment, a sealing ring is provided around the end surface of the cover body that is inserted into the accommodating cavity.
[0014] In one embodiment, the cover body further includes a connecting piece, one end of the connecting piece is connected to the cover body, and the other end is connected to the accommodating tube.
[0015] The present invention also provides a medical and sanitary clinical testing device, which includes a slide staining device for special staining of pathological histology as described in any one of the above items.
[0016] The technical solution of the present invention is to place the pathological tissue block in the accommodating cavity of the accommodating tube, then install the accommodating tube on the holding area of the base plate, and seal the accommodating tube with a glass slide. At the same time, only special staining reagents need to be added into the accommodating tube to ensure that the special staining reagents completely and adequately cover the histological specimens and prevent the specimens from drying up, without having to add reagents into a large-capacity container, thereby reducing reagent waste and saving costs. BRIEF DESCRIPTION OF THE DRAWINGS
[0017] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on the structures shown in these drawings without paying any creative work.
[0018] Figure 1 This is a structural schematic diagram of an embodiment of a slide staining device for special staining of pathological histology provided by the present invention;
[0019] Figure 2 for Figure 1 A top view of the middle substrate;
[0020] Figure 3 for Figure 1 A front view of the middle accommodating tube and the cover body;
[0021] Figure 4 for Figure 3 Bottom view of the middle accommodating tube.
[0022] Description of Figure Numbers:
[0023] 100. Staining device for special staining of pathological tissue; 1. Base plate; 11. Bump; 111. Holding space; 12. Glass slide; 13. Counterweight; 2. Accommodating tube; 21. Accommodating cavity; 211. Silicone barrier; 22. Holding arm; 23. Cover; 231. Operating unit; 232. Sealing ring; 233. Connector.
[0024] The realization of the purpose, functional features and advantages of the present invention will be further explained in conjunction with embodiments and with reference to the accompanying drawings. DETAILED DESCRIPTION
[0025] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts shall fall within the scope of protection of the present invention.
[0026] It should be noted that if the embodiments of the present invention involve directional indications (such as up, down, left, right, front, back, etc.), the directional indications are only used to explain the relative position relationship, movement status, etc. between the components in a certain specific posture. If the specific posture changes, the directional indications will also change accordingly.
[0027] In addition, if there are descriptions involving "first", "second", etc. in the embodiments of the present invention, the descriptions of "first", "second", etc. are only for descriptive purposes and cannot be understood as indicating or implying their relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features limited to "first" and "second" may explicitly or implicitly include at least one of such features. In addition, if "and / or" or "and / or" appears in the full text, its meaning includes three parallel schemes. Taking "A and / or B" as an example, it includes scheme A, or scheme B, or a scheme in which A and B are satisfied at the same time. In addition, the technical solutions between the various embodiments can be combined with each other, but it must be based on the ability of ordinary technicians in this field to implement. When the combination of technical solutions is mutually contradictory or cannot be implemented, it should be deemed that such a combination of technical solutions does not exist and is not within the scope of protection required by the present invention.
[0028] Special staining is the most basic pathological tissue chemical staining technology. During the process of dripping the reagent and incubating in a water bath, it is necessary to ensure that the special staining reagent completely and adequately covers the histological specimen to prevent the specimen from drying up. Currently, there is no special staining device for pathological histology. Usually, a conventional staining jar is used to add the staining reagent and then the glass slide is directly immersed in it, resulting in reagent waste, increased costs, and increased harmful liquid emissions. In order to solve the above problems, the utility model proposes a staining device for special staining of pathological histology and a medical and hygienic clinical testing equipment, aiming to provide a staining device for special staining of pathological histology and a medical and hygienic clinical testing equipment that reduces reagent waste, saves costs and is low in pollution. Figures 1 to 4The present invention is a structural schematic diagram of an embodiment of a slide staining device for special staining of pathological histology provided by the present invention.
[0029] Please refer to Figures 1 to 3 In one embodiment of the present invention, the staining device 100 for special staining of pathological histology includes a base plate 1 and a accommodating tube 2; the base plate 1 is provided with two protrusions 11 arranged in pairs, and a clamping interval 111 is formed between the two protrusions 11, and a slide 12 is clamped in the clamping interval 111; the accommodating tube 2 is cylindrical and has an accommodating cavity 21 therein to accommodate a pathological tissue block; one end of the accommodating tube 2 is provided with a clamping arm 22 protruding horizontally relative to each other to clamp with the two protrusions 11 and cover the slide 12.
[0030] The technical solution of the present invention is to place the pathological tissue block in the accommodating cavity 21 of the accommodating tube 2, then install the accommodating tube 2 on the holding section 111 of the substrate 1, and seal the accommodating tube 2 with a glass slide 12. At the same time, only special staining reagents need to be added to the accommodating tube 2 to ensure that the special staining reagents completely and adequately cover the histological specimens and prevent the specimens from drying up, without having to add reagents to a large-capacity container, thereby reducing reagent waste and saving costs.
[0031] In addition, please refer to Figure 1 and Figure 2 , the two protrusions 11, the glass slide 12, and the accommodating tube 2 are set as an observation group, and there are two observation groups, which are arranged at intervals on the substrate 1. It can be understood that the two protrusions 11, the glass slide 12, and the accommodating tube 2 are set as an observation group. In some embodiments, one substrate 1 carries one observation group, and generally, the observation group includes an experimental group and a control group. In this case, another substrate 1 is required to carry the observation group, and only two substrates 1 can be placed in the water bath, that is, each carrying the experimental group and the control group. Otherwise, too many substrates are placed and easy to confuse. Therefore, in other embodiments, the experimental group and the control group are set on the same substrate 1, and then more pathological tissue blocks can be heated in the water bath at the same time, thereby improving the efficiency of water heating. At the same time, the same substrate 1 carries both the experimental group and the control group, which is not easy to confuse with other experimental groups or the control group.
[0032] Furthermore, the substrate 1 is made of a hard plastic material. It is understood that the glass slide 12 needs to be held within the holding space formed by the two protruding bumps 11 provided on the substrate 1. This inevitably requires a certain degree of plastic deformation of the substrate 1 during the holding process. Therefore, the use of a hard plastic material for the substrate 1 allows for a certain degree of plastic deformation, facilitating the insertion of the glass slide 12 into the holding space. Furthermore, the high toughness of the hard plastic ensures stable and reliable holding even after repeated use.
[0033] In addition, please refer to Figure 1 The lower end surface of the substrate 1 is equipped with a counterweight 13 to allow the substrate 1 to sink into the water bath. It is understandable that in most cases, in order to accelerate the diffusion of the staining reagent into the pathological tissue block, high temperature can help accelerate the diffusion rate of the staining reagent, and most heating is to immerse the staining device 100 for special staining of pathological histology in a water bath for water bath heating. However, since the substrate 1 is made of hard plastic and the accommodating tube 2 is provided with the accommodating cavity 21, the substrate 1 cannot be immersed in water with the accommodating tube 2. Therefore, the lower end surface of the substrate 1 is equipped with the counterweight 13 to allow the substrate 1 to sink into the water bath. The counterweight 13 can be arranged in a plate shape on the lower side of the substrate 1, or it can be arranged in a plurality of blocks and evenly distributed on the lower end surface of the substrate 1. The specific arrangement form is not specifically limited here.
[0034] In addition, please refer to Figure 4 A silicone barrier layer 211 is provided around the sidewall of the accommodating chamber 21. It is understood that the dye diffuses upon heating and easily stains the accommodating tube 2. Therefore, the silicone barrier layer 211 is provided around the sidewall of the accommodating chamber 21. Since silicone is used, it is highly stable and will not react with or be stained by the dye even when heated, thus not affecting the final observation results and thereby ensuring the accuracy of the final pathology experiment.
[0035] In addition, please refer to Figure 1 The accommodating tube 2 is further provided with a cover 23 for sealing the accommodating chamber 21. It is understandable that in order to prevent impurities from entering the accommodating chamber 21 during the staining process of the staining reagent, or to prevent water from entering the accommodating tube 2 when the water bath is heated, the accommodating tube 2 is further provided with the cover 23 for sealing the accommodating chamber 21, thereby ensuring that no impurities enter the accommodating tube 2 when the staining reagent is staining the pathological tissue block, thereby affecting the experimental results, and at the same time avoiding the possibility of water entering the accommodating chamber 21 when the water bath is heated.
[0036] For further information, please refer to Figure 3 The cover 23 is also provided with an operating portion 231 for holding. It is understood that in order to facilitate the operator to seal the accommodating tube 2 with the cover 23 and to facilitate the removal of the cover 23 from the accommodating tube 2, the cover 23 is also provided with an operating portion 231, which is convenient for the operator to hold, thereby making it easier for the operator to seal the accommodating tube 2 or remove the cover 23 from the accommodating tube 2.
[0037] For further information, please refer to Figure 3 The end face of the cover 23 that is inserted into the accommodating chamber 21 is provided with a sealing ring 232. It is understood that in order to prevent water from entering the accommodating tube 2 during water bath heating and to prevent the liquid from volatilizing due to heating, the end face of the cover 23 that is inserted into the accommodating chamber 21 is provided with the sealing ring 232. The sealing performance of the sealing ring 232 prevents water from entering the accommodating tube 2 during water bath heating, thereby avoiding affecting the experimental results. In this embodiment, in order to further improve the sealing performance, the sealing ring 232 is provided with two circles.
[0038] For further information, please refer to Figure 3 The cover 23 further includes a connector 233, one end of which is connected to the cover 23 and the other end is connected to the accommodating tube 2. In some embodiments, the cover 23 and the accommodating tube 2 are separated. The accommodating cavity 21 of the accommodating tube 2 has different diameters to accommodate the sizes of various pathological tissue blocks. Therefore, corresponding to the accommodating tubes 2 of various diameters, the cover 23 should be provided one-to-one. If a separate arrangement is adopted, on the one hand, it is easy to find the cover 23 corresponding to the accommodating tube 2 among the many covers 23, which may easily cause the seal to fail or fail to seal the accommodating tube 2. On the other hand, the cover 23 may be easily lost due to repeated plugging and unplugging by the operator. Therefore, the cover 23 further includes the connector 233, one end of which is connected to the cover 23 and the other end is connected to the accommodating tube 2. In this way, the cover 23 will not be mixed up or lost.
[0039] The present invention also proposes a medical and health clinical testing equipment, which includes the staining device 100 for special staining of pathological histology. The specific structure of the staining device 100 for special staining of pathological histology refers to the above embodiment. Since the medical and health clinical testing equipment adopts all the technical solutions of all the above embodiments, it has at least all the beneficial effects brought by the technical solutions of the above embodiments, which will not be repeated here.
[0040] The above description is merely an exemplary embodiment of the present invention and does not limit the patent scope of the present invention. All equivalent structural transformations made using the contents of the present invention specification and drawings under the technical concept of the present invention, or direct / indirect application in other related technical fields are included in the patent protection scope of the present invention.
Claims
1. A staining device for special staining of pathological histology, characterized in that: include: The substrate is provided with two protrusions arranged in pairs, and a holding interval is formed between the two protrusions, and the slide is held in the holding interval; as well as, The accommodating tube is cylindrical and has an accommodating cavity therein for accommodating the pathological tissue block; one end of the accommodating tube is horizontally protruded with a holding arm for holding the two protrusions and covering the slide.
2. The slide staining device for special staining of pathological histology according to claim 1, characterized in that: The two protrusions, the glass slide, and the accommodating tube are configured as an observation group. Two observation groups are provided and are spaced apart on the substrate.
3. The slide staining device for special staining of pathological histology according to claim 1, characterized in that: The material of the substrate includes hard plastic material.
4. The slide staining device for special staining of pathological histology according to claim 1, characterized in that: A counterweight is installed on the lower end surface of the base plate so that the base plate can be sunk into the water bath.
5. The slide staining device for special staining of pathological histology according to claim 1, characterized in that: A silicone barrier layer is provided on the side wall of the accommodating cavity.
6. The slide staining device for special staining of pathological histology according to claim 1, characterized in that: The accommodating tube is further provided with a cover body for closing the accommodating cavity.
7. The slide staining device for special staining of pathological histology according to claim 6, characterized in that: The cover body is also provided with an operating portion for holding.
8. The slide staining device for special staining of pathological histology according to claim 6, characterized in that: A sealing ring is provided on the end surface of the cover body that is inserted into the accommodating cavity.
9. The slide staining device for special staining of pathological histology according to claim 6, characterized in that: The cover body further comprises a connecting piece, one end of which is connected to the cover body, and the other end of which is connected to the accommodating tube.
10. A medical and health clinical testing device, characterized in that: The medical and health clinical testing equipment includes a staining device for special staining of pathological histology as described in any one of claims 1 to 9.