Fixing device for mouse heart perfusion

Abstract

The utility model discloses a fixing device for mouse heart perfusion, which belongs to the technical field of medical instruments and comprises a square plate, a first groove is arranged in the middle of the square plate, a first threaded lead screw is rotatably connected in the first groove in a penetrating manner, and clamping plates are respectively in threaded connection with two sides of the first threaded lead screw. A first rotating handle is fixedly connected to one end of the first threaded lead screw, a square groove is formed in the square plate, a second groove is formed in the square plate, a second threaded lead screw is rotatably connected in the second groove in a penetrating mode, and a push plate is connected to the second threaded lead screw in a threaded mode; a mouse is placed between two groups of clamping plates on a square plate, the two groups of clamping plates can be driven to move towards the middle at the same time by manually rotating a first threaded screw rod, the mouse is clamped, then a push plate can be pushed to slide by rotating a second threaded screw rod, and then the heart position of the mouse is located above a square groove. And heart perfusion is facilitated.

Description

Technical Field

[0001] The utility model relates to the technical field of medical devices, in particular to a fixation device for mouse heart perfusion. Background Art

[0002] Cardiac perfusion is a crucial procedure for experimental animals, especially small mammals such as mice. Widely used in histology, physiology, pathology, and drug development, cardiac perfusion aims to study cardiac function, pathological changes, or drug effects by directly injecting specific solutions or drugs into the heart. However, traditional cardiac perfusion methods often face problems such as irrational fixture design, complex operation, and unstable fixation. These issues not only increase the difficulty and error of experiments, but may also cause unnecessary harm to experimental animals.

[0003] Existing cardiac perfusion fixation devices for mice often have the following shortcomings: First, the fixation method is single and often cannot be flexibly adjusted according to the mouse's body shape and posture, resulting in poor fixation effect; second, the device structure is complex and the operation is cumbersome, requiring a lot of time and manpower; third, it lacks stability, especially when flipping or moving the device, which can easily cause the mouse to fall off or shift in position, affecting the perfusion effect. Utility Model Content

[0004] The utility model solves the technical problems in the above-mentioned background technology and provides a fixation device for mouse heart perfusion.

[0005] In order to solve the above technical problems, the technical solutions provided by the present invention are as follows:

[0006] A fixing device for mouse cardiac perfusion comprises a square plate, a first groove is provided in the middle of the square plate, a first threaded screw is rotatably connected to the first groove, a clamping plate is threadedly connected to both sides of the first threaded screw, one end of the first threaded screw is fixedly connected to a first rotating handle, a square groove is provided on the square plate, a second groove is provided on the square plate, a second threaded screw is rotatably connected to the second groove, a push plate is threadedly connected to the second threaded screw, and one end of the second threaded screw is fixedly connected to the second rotating handle.

[0007] Preferably, fixed blocks are respectively connected to both sides of the square plate, a long rod is rotatably connected to the fixed block, and both ends of the long rod are respectively fixedly connected to support rods, and a slot is provided on the support rod.

[0008] Preferably, a square block is fixedly connected to the square plate, an insertion rod is slidably connected to the square block, one end of the insertion rod is fixedly connected to a pull handle, and a spring is sleeved on the pull handle.

[0009] Preferably, the first threaded screw is provided with two sets of opposite thread structures, the clamping plate is in an arc shape, and the clamping plate slides in the first groove.

[0010] Preferably, the first groove is located between the square groove and the second groove, the upper end of the push plate is circular, the push plate slides in the second groove, and the second groove is perpendicular to the first groove.

[0011] Preferably, the fixing blocks are provided in two groups and are distributed on both sides of the square plate, and the length of the support rod is higher than the height of the clamping plate.

[0012] Preferably, the square blocks are provided in four groups, the insertion rod passes through the slot, one end of the spring is fixedly connected to the handle, and the other end of the spring is fixedly connected to the square block.

[0013] With the above structure, the utility model has the following advantages:

[0014] 1. By placing the mouse in the middle of the two sets of clamping plates on the square plate, manually turning the first threaded screw can drive the two sets of clamping plates to move toward the middle at the same time to clamp the mouse. Then, by turning the second threaded screw, the push plate can be pushed to slide, thereby positioning the mouse's heart above the square groove, facilitating cardiac perfusion.

[0015] 2. When fixing the mouse, the support rod fits on the square plate and will not affect the operation. After the mouse is fixed, first turn the support rod 90 degrees, then insert the insertion rod into the slot on the support rod to fix it. Finally, turn the device over so that the support rod supports the device, thereby facilitating cardiac perfusion of the mouse from the square slot.

[0016] The above summary is for the purpose of description only and is not intended to be limiting in any way. In addition to the illustrative aspects, embodiments and features described above, further aspects, embodiments and features of the present invention will be readily apparent by reference to the accompanying drawings and the following detailed description. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or technical descriptions. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0018] Figure 1 This is a schematic diagram of the structure of a fixation device for mouse heart perfusion in this utility model. Figure 1 ;

[0019] Figure 2 This is a schematic diagram of the structure of a fixation device for mouse heart perfusion in this utility model. Figure 2 ;

[0020] Figure 3 yes Figure 1 A in the enlarged view.

[0021] As shown in the figure: 1. Square plate; 2. First groove; 3. First threaded screw; 4. Clamping plate; 5. First turning handle; 6. Square groove; 7. Second groove; 8. Second threaded screw; 9. Push plate; 10. Second turning handle; 11. Fixed block; 12. Long rod; 13. Support rod; 14. Square block; 15. Insert rod; 16. Pull handle; 17. Spring; 18. Slot. DETAILED DESCRIPTION

[0022] The following describes in detail embodiments of the present application. Examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present application and are not to be construed as limiting the present application.

[0023] In the description of this application, it should be noted that, unless otherwise expressly specified or limited, the terms "installed," "connected," and "connected" should be understood in a broad sense. For example, they can refer to fixed connections, detachable connections, or integral connections; they can refer to mechanical connections or electrical connections; they can refer to direct connections or indirect connections through an intermediate medium; they can refer to internal communication between two components or the interaction between two components. Those skilled in the art will understand the specific meanings of the above terms in this application based on the specific circumstances.

[0024] The following is a further detailed description of the present invention in conjunction with the full text:

[0025] Combined with attachment Figures 1 to 3The present embodiment provides a fixing device for mouse heart perfusion, comprising a square plate 1, a first groove 2 is provided in the middle of the square plate 1, a first threaded screw 3 is rotatably connected to the first groove 2, and clamping plates 4 are respectively threadedly connected on both sides of the first threaded screw 3, and one end of the first threaded screw 3 is fixedly connected to a first rotating handle 5, a square groove 6 is provided on the square plate 1, a second groove 7 is provided on the square plate 1, a second threaded screw 8 is rotatably connected to the second groove 7, a push plate 9 is threadedly connected to the second threaded screw 8, and one end of the second threaded screw 8 is fixedly connected to the second rotating handle 10. By placing the mouse in the middle of the two groups of clamping plates 4 on the square plate 1, manually rotating the first threaded screw 3 can drive the two groups of clamping plates 4 to move toward the middle at the same time, clamping the mouse, and then by rotating the second threaded screw 8, the push plate 9 can be pushed to slide, so that the heart position of the mouse is located above the square groove 6, which is convenient for cardiac perfusion.

[0026] Specifically, both sides of the square plate 1 are respectively connected with a fixed block 11, and a long rod 12 is rotatably connected to the fixed block 11. The two ends of the long rod 12 are respectively fixedly connected to a support rod 13, and a slot 18 is provided on the support rod 13. A square block 14 is fixedly connected to the square plate 1, and an insertion rod 15 is slidably connected to the square block 14. One end of the insertion rod 15 is fixedly connected to a pull handle 16, and a spring 17 is sleeved on the pull handle 16. Two sets of opposite thread structures are provided on the first threaded screw 3. The shape of the clamping plate 4 is arc-shaped, and the clamping plate 4 slides in the first groove 2. The first groove 2 is located in the middle of the square groove 6 and the second groove 7. The upper end of the push plate 9 is circular, and the push plate 9 slides in the second groove 7. The second groove 7 is perpendicular to the first groove 2, and the first groove 2 is located in the middle of the square groove 6 and the second groove 7. The push plate 9 The upper end is circular, and the push plate 9 slides in the second groove 7. The second groove 7 is perpendicular to the first groove 2. The fixing block 11 is provided with two groups and is distributed on both sides of the square plate 1. The length of the support rod 13 is higher than the height of the clamping plate 4. The square block 14 is provided with four groups. The insertion rod 15 passes through the slot 18. One end of the spring 17 is fixedly connected to the pull handle 16, and the other end of the spring 17 is fixedly connected to the square block 14. When fixing the mouse, the support rod 13 fits the square plate 1 and will not affect the operation. After the mouse is fixed, first turn the support rod 13 ninety degrees, and then insert the insertion rod 15 into the slot 18 on the support rod 13. The support rod 13 is not seen to be fixed. Finally, the device is turned over so that the support rod 13 supports the device, thereby facilitating cardiac perfusion of the mouse from the square groove 6.

[0027] The operation steps are as follows: the operator places the heart of the mouse above the square groove 6 on the square plate 1 according to the size of the mouse, and then manually rotates the second handle 10 to drive the second screw rod 8 to rotate, pushing the push plate 9 to slide in the second groove 7 toward the square groove 6 until it fits the tail of the mouse, and then manually rotates the first handle 5 to drive the first screw rod 3 to rotate, driving the two sets of clamping plates 4 to slide toward the middle in the first groove 2 at the same time to fix the mouse, and finally, rotates the support rod 13 ninety degrees in turn, and drives the support rod 13 to rotate ninety degrees. The movable rod 12 rotates on the fixed block 11. When the support rod 13 fits the insertion rod 15, it pushes the insertion rod 15 to slide outward on the square block 14 and stretches the spring 17 until the support rod 13 rotates to ninety degrees. The position of the insertion rod 15 and the slot 18 are adjusted. Under the action of the spring 17, the insertion rod 15 is reset and inserted into the slot 18, thereby fixing the support rod 13. Then, the device is turned over so that the four groups of support rods 13 fit the ground to support the device, and then the mouse can be perfused by heart through the square slot 6.

[0028] The above description of the present invention and its embodiments is non-limiting. What is shown in the full text is only one embodiment of the present invention, and the actual structure is not limited thereto. In short, if a person skilled in the art is inspired by this and, without departing from the purpose of the present invention, designs a structure and embodiment similar to the technical solution without creatively designing, they shall fall within the scope of protection of the present invention.

Claims

1. A fixation device for mouse cardiac perfusion, comprising a square plate (1), characterized in that: A first groove (2) is provided in the middle of the square plate (1), a first threaded screw (3) is rotatably connected to the first groove (2), clamping plates (4) are respectively threadedly connected to both sides of the first threaded screw (3), one end of the first threaded screw (3) is fixedly connected to a first rotating handle (5), a square groove (6) is provided on the square plate (1), a second groove (7) is provided on the square plate (1), a second threaded screw (8) is rotatably connected to the second groove (7), a push plate (9) is threadedly connected to the second threaded screw (8), and one end of the second threaded screw (8) is fixedly connected to a second rotating handle (10).

2. The fixation device for mouse cardiac perfusion according to claim 1, characterized in that: Both sides of the square plate (1) are respectively connected with fixed blocks (11), a long rod (12) is rotatably connected to the fixed block (11), and both ends of the long rod (12) are respectively fixedly connected with support rods (13), and a slot (18) is provided on the support rod (13).

3. The fixation device for mouse cardiac perfusion according to claim 2, characterized in that: A square block (14) is fixedly connected to the square plate (1), an insertion rod (15) is slidably connected to the square block (14), one end of the insertion rod (15) is fixedly connected to a pull handle (16), and a spring (17) is sleeved on the pull handle (16).

4. The fixation device for mouse cardiac perfusion according to claim 3, characterized in that: The first threaded screw (3) is provided with two sets of opposite thread structures, the clamping plate (4) is in an arc shape, and the clamping plate (4) slides in the first groove (2).

5. The fixation device for mouse cardiac perfusion according to claim 4, characterized in that: The first groove (2) is located between the square groove (6) and the second groove (7), the upper end of the push plate (9) is circular, the push plate (9) slides in the second groove (7), and the second groove (7) is perpendicular to the first groove (2).

6. The fixation device for mouse cardiac perfusion according to claim 5, characterized in that: The fixing blocks (11) are provided in two groups and are distributed on both sides of the square plate (1). The length of the support rod (13) is higher than the height of the clamping plate (4).

7. The fixation device for mouse cardiac perfusion according to claim 6, characterized in that: The square blocks (14) are provided with four groups, the insertion rod (15) passes through the slot (18), one end of the spring (17) is fixedly connected to the pull handle (16), and the other end of the spring (17) is fixedly connected to the square block (14).

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