Connecting pipeline special for double plasma exchange treatment

Abstract

The utility model provides a special connecting pipeline for double plasma exchange treatment, which is used for connecting a plasma component separator and a plasma separator, and comprises an artery tube, a vein tube, a waste liquid tube, a return tube, a plasma tube, a pressure measuring tube and a waste liquid bag, one end of the artery tube and one end of the vein tube are respectively connected to two ends of the plasma separator, and the other end of the artery tube and the other end of the vein tube are respectively connected to the other end of the plasma separator; a side port of the plasma separator is connected with the plasma tube, the other end of the plasma tube is fixedly connected with the end of the plasma component separator, the other end of the plasma component separator is fixedly connected with the waste liquid tube, and the other end of the waste liquid tube is fixedly connected with the waste liquid bag. A side port of the plasma component separator is fixedly connected with a return pipe, the other end of the return pipe is communicated with an arterial duct, and a pressure measuring pipe is arranged on the arterial duct in a communicated mode. The connecting pipe does not need to be installed repeatedly, consumables are saved, use is convenient, and sterile operation is guaranteed.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a special connecting pipeline for double plasma exchange treatment. Background Art

[0002] Double filtration plasmapheresis (DFPP) involves separating plasma from a plasma separator into larger and smaller molecular weight components using a plasma fractionator. The larger molecular weight components, including pathogenic substances such as IgG and LDL-C, are discarded, while the smaller molecular weight components, including useful substances such as albumin, are returned to the body. Compared with traditional plasma exchange, this procedure offers advantages such as minimal loss of the patient's own useful, non-pathogenic substances, such as albumin, and significantly reduces complications associated with large-volume plasma transfusions. Consequently, double filtration plasmapheresis (DFPP) has been gradually adopted in clinical practice.

[0003] Currently, there are four plasma component separators with different pore sizes available clinically, which can effectively remove target substances with minimal albumin loss. They are mainly used clinically for metabolic diseases such as hypercholesterolemia; rheumatic diseases such as systemic lupus erythematosus; and immune nervous system diseases such as acute inflammatory demyelinating polyneuropathy.

[0004] Currently, dual plasmapheresis in clinical practice typically involves a plasma separator and a plasma component separator connected in series. Proper connection of the two filters is crucial for ensuring the effectiveness of dual plasmapheresis. However, the commonly used system, which consists of an infusion set, a three-way valve, and a female-female connector, is complex, prone to disconnection, and lacks assurance of sterility during the procedure, requiring improvement. Summary of the Invention

[0005] To address the aforementioned issues, the present invention discloses a dedicated connecting tubing system for dual plasma exchange therapy. This system connects a plasma component separator to a plasma separator. The connecting tubing includes an arterial line, a venous line, a waste line, a return line, a plasma line, a pressure gauge, and a waste bag. Existing tubing used in dual plasma exchange therapy is typically assembled by cutting and assembling existing medical hoses, such as infusion tubing and disposable connectors. The present invention designs a dedicated tubing system specifically for dual plasma exchange therapy.

[0006] One end of the arterial tube and the venous tube are respectively connected to the two ends of the plasma separator, the side port of the plasma separator is connected to the plasma tube, the other end of the plasma tube is fixedly connected to the end of the plasma component separator, the other end of the plasma component separator is fixedly connected to the waste liquid tube, the other end of the waste liquid tube is fixedly connected to the waste liquid bag, the side port of the plasma component separator is fixedly connected to the return tube, and the other end of the return tube is connected to the arterial tube. The pipeline constructed is consistent with existing double plasma exchange treatment, that is, blood output from the artery is sent to the plasma separator through the venous tube, and the filtered blood is then input into the human body through the arterial tube. At the same time, the plasma filtered by the plasma separator enters the plasma component separator, and the filtered non-harmful substances enter the arterial tube through the return tube.

[0007] The arterial tube is connected to a pressure measuring tube, and the return tube is located between the pressure measuring tube and the plasma separator. The pressure measuring tube is used to connect to a pressure sensor to measure the pressure of the blood returning from the arterial tube.

[0008] Preferably, the ends of the arterial tube, venous tube, waste liquid tube, return tube and plasma tube are all provided with threaded connection sleeves. That is, each pipeline is fixedly connected by threaded connection. If an indwelling needle is used, both ends of the arterial tube and venous tube are provided with threaded connection sleeves.

[0009] Preferably, one end of the arterial tube and the venous tube are provided with a needle. If an indwelling needle is not used, a threaded connection sleeve is provided at one end of the arterial tube or the venous tube and a needle is provided at the other end for ease of use.

[0010] Preferably, one of the corners of the waste liquid bag is provided with a hanging hole, that is, two hanging holes are provided on the waste liquid bag, so that the waste liquid bag can be hung forward or inverted.

[0011] Preferably, the waste liquid bag is provided with a connection port, and one end of the waste liquid pipe is connected to the connection port to introduce the generated waste into the waste liquid bag.

[0012] Preferably, a sleeve is provided at one end of the connection port located inside the waste liquid bag, and one end of the sleeve is reduced in diameter and flattened, i.e., it is arranged to contact the inner wall. The sleeve functions as a one-way valve. The reduced and flattened end of the sleeve means that waste liquid enters the sleeve from the connection port and passes through the flattened end into the waste liquid bag. However, the flattened structure prevents waste liquid stored in the waste liquid bag from passing through, thus achieving a one-way conduction effect.

[0013] Preferably, a pressure pot is provided on the pressure measuring tube, and a first nozzle and a second nozzle are provided side by side at one end of the pressure pot. The arterial tube is cut off and connected to the first nozzle and the second nozzle, respectively. The first nozzle and the second nozzle are at different heights within the pressure pot. The pressure pot is provided to prevent blood from backwashing into the pressure sensor by providing a larger volume. At the same time, the first nozzle and the second nozzle are at different heights. The lower first nozzle leads to the human body, thereby preventing gas from entering the human body or collecting gas in the pipeline into the pressure pot.

[0014] The beneficial effects of the present invention are as follows:

[0015] 1. The connecting pipeline has a simple structure, easy operation, strong practicality, and does not require repeated installation. It not only saves consumables and is easy to use, but also ensures the sterility of the operation.

[0016] 2. A pressure pot is provided to accommodate possible gas in the pipeline to prevent bubbles from entering the human body. At the same time, if the pressure in the pipeline increases or the pressure sensor is depressurized, the larger volume of the pressure pot can accommodate more recoil blood and reduce the problem of blood contamination of the pressure sensor. At the same time, some blood needs to be temporarily stored in the pressure pot to prevent the internal pressure of the pressure pot from increasing, which may cause gas to enter the pipeline.

[0017] 3. A seal is provided at the end of the connection port on the waste liquid bag to play a one-way conduction effect and prevent the waste liquid from flowing back out of the waste liquid bag. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is a connection diagram of the present invention;

[0019] Figure 2 is a schematic cross-sectional view of a pressure pot of the present invention;

[0020] Figure 3 This is a schematic diagram of the waste liquid bag connection port of the present invention;

[0021] Figure 4 It is a schematic diagram of the end structure of the envelope of the present invention.

[0022] List of reference numerals:

[0023] 1. Arterial tube; 2. Venous tube; 3. Plasma component separator; 4. Waste liquid tube; 5. Hanging hole; 6. Waste liquid bag; 7. Reflux tube; 8. Plasma tube; 9. Pressure measuring tube; 10. Pressure pot; 11. Plasma separator; 12. First tube opening; 13. Second tube opening; 14. Connecting port; 15. Envelope. DETAILED DESCRIPTION

[0024] The present invention will be further described below with reference to the accompanying drawings and specific embodiments. It should be understood that the following specific embodiments are intended only to illustrate the present invention and are not intended to limit the scope of the present invention. It should be noted that the terms "front," "rear," "left," "right," "up," and "down" used in the following description refer to directions in the accompanying drawings, and the terms "inward" and "outward" refer to directions toward or away from the geometric center of a particular component, respectively.

[0025] like Figures 1 to 4 As shown, a special connecting pipeline for double plasma exchange treatment is used to connect the plasma component separator 3 and the plasma separator 11. The connecting pipe includes an arterial tube 1, a venous tube 2, a waste liquid tube 4, a return tube 7, a plasma tube 8, a pressure measuring tube 9 and a waste liquid bag 6.

[0026] One end of the arterial tube 1 and the venous tube 2 are respectively connected to the two ends of the plasma separator 11, the side port of the plasma separator 11 is connected to the plasma tube 8, the other end of the plasma tube 8 is fixedly connected to the end of the plasma component separator 3, the other end of the plasma component separator 3 is fixedly connected to the waste liquid tube 4, the other end of the waste liquid tube 4 is fixedly connected to the waste liquid bag 6, the side port of the plasma component separator 3 is fixedly connected to the reflux tube 7, and the other end of the reflux tube 7 is communicated with the arterial tube 1.

[0027] After assembly, physiological saline needs to be injected into the pipeline to evacuate the gas in the pipeline. At this time, the relevant pipelines are installed on the peristaltic pump as needed. For example, the venous tube 2 is wrapped around the peristaltic pump. Here, the venous tube 2 draws blood from the human body and sends it to the plasma separator 11. The filtered blood returns to the human body through the arterial tube 1, and the filtered plasma is sent to the plasma component separator 3. The filtered liquid enters the arterial tube 1 through the return tube 7 and returns to the human body. The waste liquid is sent to the waste liquid bag 6.

[0028] The arterial tube 1 is connected to a pressure measuring tube 9, and the return tube 7 is located between the pressure measuring tube 9 and the plasma separator 11. The pressure measuring tube 9 is used to monitor the pressure in the arterial tube 1 to ensure that the return pressure is stable.

[0029] The ends of the arterial tube 1, venous tube 2, waste tube 4, return tube 7, and plasma tube 8 are all equipped with threaded connectors. This facilitates assembly and connection. The ends can be colored to indicate correct connection, increasing connection speed. Here, if both the ends of the arterial tube 1 and venous tube 2 are threaded connectors, an indwelling catheter is being used. The arterial tube 1, venous tube 2, and indwelling catheter are threadedly connected.

[0030] One end of the arterial tube 1 and the venous tube 2 is provided with a needle. No indwelling needle is provided in the patient's body here, so the end of the arterial tube 1 and the venous tube 2 is provided with a needle.

[0031] One of the two corners of the waste liquid bag 6 is provided with a hanging hole 5. That is, two hanging holes 5 are provided to facilitate the hanging use of the waste liquid bag 6.

[0032] The waste liquid bag 6 is provided with a connecting port 14, and one end of the waste liquid tube 4 is connected to the connecting port 14. It is convenient to connect and use the waste liquid bag 6. Further, the waste liquid tube 4 and the waste liquid bag 6 are integrated to reduce the number of connections.

[0033] A sleeve 15 is sleeved onto one end of the connection port 14 located within the waste liquid bag 6. One end of the sleeve 15 is narrowed and flattened, i.e., it is positioned in close contact with the inner wall. This sleeve 15 acts as a one-way valve, preventing waste liquid from flowing back through the connection port 14 and facilitating subsequent separation and disposal of the waste liquid bag 6.

[0034] A pressure pot 10 is provided on the pressure measuring tube 9. The pressure pot 10 increases the volume, reduces the probability of blood backwash and contamination of the pressure sensor, and can also accommodate possible bubbles in the pipeline. A first pipe port 12 and a second pipe port 13 are provided side by side at one end of the pressure pot 10, and the arterial tube 1 is cut off, and the first pipe port 12 and the second pipe port 13 are connected respectively. The first pipe port 12 and the second pipe port 13 have different internal port heights of the pressure pot 10, that is, the higher second pipe port 13 is connected to the plasma separator 11, and the lower first pipe port 12 is connected to the human body. The first pipe port 12 is low in height to ensure that there are no bubbles in the blood sent to the human body.

[0035] The technical means disclosed in the solution of the present invention are not limited to the technical means disclosed in the above-mentioned embodiment, but also include technical solutions composed of any combination of the above technical features.

Claims

1. A special connecting pipeline for double plasma exchange treatment, which is used to connect a plasma component separator (3) and a plasma separator (11), characterized in that: The connecting tube comprises an arterial tube (1), a venous tube (2), a waste liquid tube (4), a return tube (7), a plasma tube (8), a pressure measuring tube (9) and a waste liquid bag (6); One end of the arterial tube (1) and the venous tube (2) are respectively connected to the two ends of the plasma separator (11), the side port of the plasma separator (11) is connected to the plasma tube (8), the other end of the plasma tube (8) is fixedly connected to the end of the plasma component separator (3), the other end of the plasma component separator (3) is fixedly connected to the waste liquid tube (4), the other end of the waste liquid tube (4) is fixedly connected to the waste liquid bag (6), the side port of the plasma component separator (3) is fixedly connected to the return tube (7), and the other end of the return tube (7) is communicated with the arterial tube (1); The arterial tube (1) is connected to a pressure measuring tube (9), and the reflux tube (7) is located on the arterial tube (1) between the pressure measuring tube (9) and the plasma separator (11).

2. A double plasma exchange treatment dedicated connecting pipeline according to claim 1, characterized in that: The ends of the arterial tube (1), venous tube (2), waste liquid tube (4), return tube (7) and plasma tube (8) are all provided with threaded connection sleeves.

3. The double plasma exchange treatment dedicated connecting pipeline according to claim 2, characterized in that: One end of the arterial tube (1) and the venous tube (2) is provided with a needle.

4. The double plasma exchange treatment dedicated connecting pipeline according to claim 1, characterized in that: One pair of corners of the waste liquid bag (6) is provided with hanging holes (5).

5. The double plasma exchange treatment dedicated connecting pipeline according to claim 1, characterized in that: The waste liquid bag (6) is provided with a connection port (14), and one end of the waste liquid tube (4) is connected to the connection port (14).

6. The double plasma exchange treatment dedicated connecting pipeline according to claim 5, characterized in that: One end of the connection port (14) located inside the waste liquid bag (6) is sleeved with a sleeve (15), and one end of the sleeve (15) is reduced in diameter and flat, that is, it is arranged in contact with the inner wall.

7. The double plasma exchange treatment dedicated connecting pipeline according to claim 1, characterized in that: A pressure pot (10) is provided on the pressure measuring tube (9), and a first pipe opening (12) and a second pipe opening (13) are provided side by side at one end of the pressure pot (10). The arterial tube (1) is cut off, and the first pipe opening (12) and the second pipe opening (13) are connected respectively. The first pipe opening (12) and the second pipe opening (13) are at different internal port heights of the pressure pot (10).

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