Glass-lined reaction kettle for producing bulk pharmaceutical chemicals

Abstract

The utility model relates to a glass-lined reaction kettle for raw material medicine production, and belongs to the technical field of eye drop raw material production. The glass-lined reaction kettle comprises a kettle body, a kettle cover, a sealing outer cylinder, a movable sealing rod, a traction rope, a connecting pipe and a ventilation drying assembly; the kettle cover covers an opening of the kettle body, a pair of sealing outer cylinders which are symmetrically distributed are arranged on the surface of the kettle cover, and movable sealing rods which are positioned in the kettle body are arranged in the sealing outer cylinders in a sliding and sealing manner. According to the glass-lined reaction kettle for raw material medicine production, an arranged traction piece pulls a traction rope to drive a spraying ring to move up and down, vertical movement of the spraying ring is achieved in cooperation with telescopic supporting of a sealing outer cylinder and a movable sealing rod, and meanwhile cleaning liquid enters through a connecting pipe and is discharged into the spraying ring through a hose; and after cleaning is completed, hot air flow is introduced into the arranged ventilation drying assembly and is blown out through the spraying ring, drying in the kettle body after cleaning is achieved, and the cleaning efficiency and effect are improved.

Description

Technical Field

[0001] The utility model relates to the technical field of eye drop raw material production, in particular to a glass-lined reactor for raw material medicine production. Background Art

[0002] Tropicamide eye drops are a commonly used ophthalmic drug, mainly used for pupil dilation during ophthalmic examinations and surgery. It is an anticholinergic drug that inhibits the contraction of the smooth muscles of the iris and ciliary muscles, leading to pupil dilation and ciliary muscle paralysis. Therefore, tropicamide is an important raw material in the preparation of eye drops.

[0003] When tropicamide is used as a raw material, a glass-lined reactor is often used for production to achieve a mixing reaction of the materials. However, tropicamide needs to be produced in batches. After the reaction in the glass-lined reactor is completed, it needs to be cleaned before reacting again. Generally, during cleaning, a cleaning agent is added to the reactor and stirred for cleaning. However, this cleaning method easily causes attachments to be unable to be cleaned, and the cleaning is not comprehensive, resulting in residual moisture after cleaning. Therefore, the present application designs a glass-lined reactor for raw material production with improved cleaning effect to solve this technical defect of the prior art. Utility Model Content

[0004] In view of the deficiencies in the prior art, the utility model provides a glass-lined reactor for the production of bulk medicines.

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a glass-lined reactor for the production of raw materials, comprising a reactor body, a reactor cover, a sealing outer cylinder, a movable sealing rod, a traction rope, a connecting pipe and a ventilation and drying assembly;

[0006] The kettle cover is provided at the opening of the kettle body, and a pair of symmetrically distributed sealing outer cylinders are provided on the surface of the kettle cover. A movable sealing rod located in the kettle body is slidably sealed in the sealing outer cylinders, and a connecting pipe is provided between the other ends of the sealing outer cylinders;

[0007] A spray ring for discharging spray cleaning liquid is provided between the other ends of the movable sealing rod, and a hose is connected between the spray ring and the connecting pipe;

[0008] The bottom wall of the movable sealing rod is provided with a traction rope passing through the sealing outer cylinder and the connecting pipe;

[0009] A traction member is provided on the surface of the connecting pipe, and the traction member pulls the traction rope;

[0010] The ventilation and drying component is installed on the surface of the kettle cover, and the ventilation and drying component discharges hot air into the connecting pipe.

[0011] As a preferred technical solution of the utility model, it also includes a liquid supply component,

[0012] The liquid supply assembly includes a liquid supply pipe arranged outside the connecting pipe, a liquid pump is provided at the other end of the liquid supply pipe, and a cleaning liquid storage tank is provided at the liquid extraction port of the liquid extraction pump.

[0013] By adopting the above technical solution, it is convenient to discharge the cleaning liquid in the cleaning liquid storage tank into the connecting pipe through the liquid suction pump.

[0014] As a preferred technical solution of the present invention, a liquid suction pipe is provided between the liquid suction port of the liquid suction pump and the cleaning liquid storage tank, and a sealing cover is provided on the surface opening of the cleaning liquid storage tank.

[0015] The above technical solution makes it easy to open the cover and add cleaning liquid to the cleaning liquid storage box.

[0016] As an optimal technical solution of the present invention, the traction member includes a bidirectional output motor installed on the surface of the connecting pipe, a rotating shaft is installed at the output shaft at both ends of the bidirectional output motor, and a winding disk for winding and fixing the traction rope is installed at the axis of the rotating shaft.

[0017] The above technical solution is adopted to facilitate starting the bidirectional output motor to drive the winding disk to rotate and pull the traction rope.

[0018] As a preferred technical solution of the present invention, limit seats symmetrically arranged on both sides of the surface of the connecting pipe are rotatably sleeved on the outside of the rotating shaft.

[0019] The above technical solution facilitates limiting the rotation of the rotating shaft through the limiting seat, thereby ensuring the stability of the rotating shaft rotation.

[0020] As an optimal technical solution of the present invention, the ventilation and drying component includes a heating seat arranged on the surface of the kettle cover, the surface of the heating seat is connected to a blower, a filter cover is provided at the air inlet of the blower, and an exhaust pipe is connected between the heating seat and the connecting pipe.

[0021] The above technical solution facilitates the injection of hot air into the connecting pipe through the ventilation and drying component.

[0022] As a preferred technical solution of the present invention, the filter screen is filled with activated carbon particles, and the heating base is provided with a heating wire.

[0023] By adopting the above technical solution, the incoming gas can be filtered, cleaned and heated.

[0024] As an optimal technical solution of the present invention, the spray ring includes a hollow circular ring connected to the hose and connected to the movable sealing rod, the outer peripheral wall of the hollow circular ring is provided with a plurality of high-pressure nozzles, and the upper surface of the hollow circular ring is provided with a plurality of L-shaped high-pressure nozzles.

[0025] The above technical solution facilitates all-round cleaning of the interior of the kettle body through the high-pressure nozzles on the spray ring and the L-shaped high-pressure nozzles.

[0026] As a preferred technical solution of the present invention, the kettle cover is provided with an annular sealing groove for the spray ring to be placed and sealed.

[0027] The above technical solution ensures that when the spray ring is not cleaned, the annular seal is placed in the groove to seal and protect the spray ring.

[0028] As an optimal technical solution of the present invention, a stirring motor is provided on the surface of the kettle cover, and a stirring rod located in the kettle body is installed on the output shaft of the stirring motor.

[0029] By adopting the above technical solution, the stirring motor drives the stirring rod to stir the raw materials in the kettle body.

[0030] Compared with the existing technology, the technical solution of this application has the following beneficial effects:

[0031] The glass-lined reactor for the production of raw materials has a traction rope that drives the spray ring to move up and down after the reaction of tropicamide is completed and the material is discharged from the glass-lined reactor. The spray ring is moved vertically in conjunction with the telescopic support of the sealing outer cylinder and the movable sealing rod. At the same time, the cleaning liquid enters through the connecting pipe and is discharged into the spray ring through the hose, so that the spray ring moves to spray and clean the reactor body in all directions. After the cleaning is completed, the ventilation and drying component is set to let in hot air, which is blown out through the spray ring to achieve drying after cleaning in the reactor body, thereby improving the cleaning efficiency and effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0032] Figure 1 It is a three-dimensional diagram of the utility model;

[0033] Figure 2 This is a three-dimensional diagram of the interior of the kettle of the utility model;

[0034] Figure 3 For this utility model Figure 2 Front view of

[0035] Figure 4 This is an enlarged three-dimensional view of point A of the present utility model;

[0036] Figure 5 This is a side perspective view of the present utility model;

[0037] Figure 6 For this utility model Figure 3 Side view of the stereogram.

[0038] In the figure: 1. Kettle body; 2. Kettle cover; 3. Sealing outer cylinder; 4. Movable sealing rod; 5. Spray ring; 51. Hollow ring; 52. High-pressure nozzle; 53. L-shaped high-pressure nozzle; 6. Traction rope; 7. Bidirectional output motor; 8. Rotating shaft; 9. Winding disk; 10. Connecting pipe; 11. Hose; 12. Cleaning liquid storage tank; 13. Liquid pump; 14. Liquid supply pipe; 15. Heating seat; 16. Blower; 17. Filter cover; 18. Exhaust pipe; 19. Stirring motor; 20. Stirring rod; 21. Ring seal is placed in the groove. DETAILED DESCRIPTION

[0039] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0040] See also Figure 1-2 The glass-lined reactor for the production of bulk drugs in this embodiment includes a reactor body 1, a reactor cover 2, a sealing outer cylinder 3, a movable sealing rod 4, a traction rope 6, a connecting pipe 10 and a ventilation and drying component.

[0041] A stirring motor 19 is fixed to the upper surface of the kettle cover 2 by fastening screws, and a stirring rod 20 located in the kettle body 1 is fixed to the output shaft of the stirring motor 19. When the tropicamide raw material mixing reaction is carried out, a variety of tropicamide raw materials are put into the kettle body 1 through the feeding port provided on the kettle cover 2. When the stirring motor 19 drives the stirring rod 20 to rotate to mix the materials, the heating system provided on the kettle body 1 is cooperated to realize the mixing reaction of the tropicamide raw materials.

[0042] The kettle cover 2 is arranged on the opening of the upper surface of the kettle body 1 to seal the opening. A pair of symmetrically distributed sealing outer cylinders 3 are fixedly installed on the upper surface of the kettle cover 2. A movable sealing rod 4 located in the kettle body 1 is slidably sealed inside the sealing outer cylinder 3. A connecting pipe 10 is fixedly installed between the other ends of the sealing outer cylinder 3.

[0043] A spray ring 5 for discharging spray cleaning liquid is fixedly installed between the other ends of the movable sealing rod 4, and a hose 11 is connected between the spray ring 5 and the connecting pipe 10. The spray ring 5 includes a hollow circular ring 51 connected to the hose 11 and connected to the movable sealing rod 4. The outer peripheral wall of the hollow circular ring 51 is connected to a plurality of annularly equidistantly distributed high-pressure nozzles 52, and the upper surface of the hollow circular ring 51 is connected to a plurality of annularly equidistantly distributed L-shaped high-pressure nozzles 53.

[0044] It should be added that the opening of the L-shaped high-pressure nozzle 53 is arranged toward the center of the kettle body 1 , and when the movable sealing rod 4 moves in the sealing outer cylinder 3 , the hose 11 deforms adaptively.

[0045] See also Figure 3-4 A traction rope 6 passing through the sealing outer cylinder 3 and the connecting pipe 10 is fixedly installed on the bottom wall of the inner cavity of the movable sealing rod 4.

[0046] The traction rope 6 is a deformable stainless steel braided rope.

[0047] A traction member is provided on the surface of the connecting tube 10, and the traction member pulls the traction rope 6. The traction member includes a bidirectional output motor 7 fixed to the middle of the upper surface of the connecting tube 10 by fastening screws, and a rotating shaft 8 is fixed to the output shafts at both ends of the bidirectional output motor 7. A winding disk 9 for winding and fixing the traction rope 6 is fixed to the axis of the other end of the rotating shaft 8. The upper surface of the connecting tube 10 has limit seats symmetrically rotatably sleeved on the outside of the rotating shaft 8 on both sides.

[0048] The bidirectional output motor 7 drives the winding disc 9 on the rotating shaft 8 to rotate forward and reverse to achieve the winding and loosening of the traction rope 6 on the winding disc 9.

[0049] The kettle cover 2 is provided with an annular sealing groove 21 for the spray ring 5 to be placed and sealed.

[0050] Among them, after cleaning is completed, the bidirectional output motor 7 drives the winding disk 9 to reel in the traction rope 6, and pulls the spray ring 5 to move to the annular seal and put it into the groove 21 to seal and protect the spray ring 5 to avoid corrosion.

[0051] See also Figure 5-6The ventilation and drying component is installed on the surface of the kettle cover 2, and the ventilation and drying component discharges hot air into the connecting pipe 10. The ventilation and drying component includes a heating seat 15 fixed to the upper surface of the kettle cover 2 by fastening screws. The front surface of the heating seat 15 is connected to a blower 16, and the air inlet of the blower 16 is connected to a filter screen cover 17. An exhaust pipe 18 is connected between the heating seat 15 and the connecting pipe 10. The filter screen cover 17 is filled with activated carbon particles, and a heating wire is fixed in the heating seat 15.

[0052] It should be added that the filter cover 17 is a cylindrical filter screen. When the blower 16 is working, the external air flow enters through the filter cover 17, and the activated carbon particles inside adsorb impurities in the air. At the same time, the incoming air flow enters the heating seat 15 and is heated by the heating wire.

[0053] The present application also includes a liquid supply component, which includes a liquid supply pipe 14 connected to the outside of the connecting pipe 10, the other end of the liquid supply pipe 14 is connected to a liquid pump 13, the liquid suction port of the liquid pump 13 is connected to a cleaning liquid storage tank 12, and a liquid suction pipe is connected between the liquid suction port of the liquid pump 13 and the cleaning liquid storage tank 12, and a sealing cover is provided at the surface opening of the cleaning liquid storage tank 12.

[0054] It should be added that the liquid pump 13 is fixed to the surface of the cleaning liquid storage tank 12 by fastening screws, and the cleaning liquid storage tank 12 can be replenished with cleaning liquid by opening the cover.

[0055] The working principle of the above embodiment is:

[0056] When in use, after the tropicamide raw material is placed into the kettle body 1, the stirring motor 19 is driven to rotate the stirring rod 20 to promote the stirring and mixing reaction of the raw materials in the kettle body 1. After the reaction is completed, the discharge switch valve is opened to discharge the material;

[0057] The liquid extraction pump 13 is provided to extract the cleaning liquid stored in the cleaning liquid storage tank 12. The cleaning liquid is ejected from the high-pressure nozzles 52 and the L-shaped high-pressure nozzles 53 by virtue of the interconnection among the liquid extraction pump 13, the liquid supply pipe 14, the connecting pipe 10, the hose 11, the hollow ring 51, the high-pressure nozzle 52 and the L-shaped high-pressure nozzle 53. The high-pressure nozzle 52 sprays and cleans the inner wall of the kettle body 1, and the L-shaped high-pressure nozzle 53 sprays and cleans the internal structure of the kettle body 1.

[0058] When the liquid pump 13 is working, the bidirectional output motor 7 is started synchronously to drive the winding disk 9 on the rotating shaft 8 to rotate. The winding disk 9 rotates to retract and release the traction rope 6. When the traction rope 6 is retracted and released, the movable sealing rod 4 moves in the sealing outer cylinder 3, thereby driving the spray ring 5 on the movable sealing rod 4 to move in the kettle body 1, and performing all-round spray cleaning on the kettle body 1, thereby improving the cleaning efficiency and effect;

[0059] In addition, after the spray cleaning is completed, the blower 16 is started to blow out air flow, and the outside air enters the blower 16 through the filter cover 17, and the impurities in the air are filtered. The filtered air flow enters the heating seat 15 to heat the air flow, and the heating seat 15, exhaust pipe 18, connecting pipe 10, hose 11, hollow ring 51, high-pressure nozzle 52 and L-shaped high-pressure nozzle 53 are interconnected to make the hot air flow blown out from the high-pressure nozzle 52 and the L-shaped high-pressure nozzle 53, and cooperate with the up and down movement of the spray ring 5 to achieve the drying of the cleaned kettle body 1, which is convenient for the next feeding reaction.

[0060] The electrical components mentioned in this article are all electrically connected to the main controller and the power supply. The main controller can be a conventional known device that controls a computer, etc., and the existing public power connection technology is not described in detail in this article.

Claims

1. Glass-lined reactor for API production, characterized by: It includes kettle body, kettle cover, sealing outer cylinder, movable sealing rod, traction rope, connecting pipe and ventilation and drying assembly; The kettle cover is provided at the opening of the kettle body, and a pair of symmetrically distributed sealing outer cylinders are provided on the surface of the kettle cover. A movable sealing rod located in the kettle body is slidably sealed in the sealing outer cylinders, and a connecting pipe is provided between the other ends of the sealing outer cylinders; A spray ring for discharging spray cleaning liquid is provided between the other ends of the movable sealing rod, and a hose is connected between the spray ring and the connecting pipe; The bottom wall of the movable sealing rod is provided with a traction rope passing through the sealing outer cylinder and the connecting pipe; A traction member is provided on the surface of the connecting pipe, and the traction member pulls the traction rope; The ventilation and drying component is installed on the surface of the kettle cover, and the ventilation and drying component discharges hot air into the connecting pipe.

2. The glass-lined reactor for the production of bulk drugs according to claim 1, characterized in that: Also includes a liquid supply assembly, The liquid supply assembly includes a liquid supply pipe arranged outside the connecting pipe, a liquid pump is provided at the other end of the liquid supply pipe, and a cleaning liquid storage tank is provided at the liquid extraction port of the liquid extraction pump.

3. The glass-lined reactor for the production of bulk drugs according to claim 2, characterized in that: A liquid extraction pipe is provided between the liquid extraction port of the liquid extraction pump and the cleaning liquid storage tank, and a sealing cover is provided on the surface opening of the cleaning liquid storage tank.

4. The glass-lined reactor for the production of bulk drugs according to claim 1, characterized in that: The traction member includes a bidirectional output motor installed on the surface of the connecting pipe. A rotating shaft is installed at the output shafts at both ends of the bidirectional output motor. A winding disk for winding and fixing the traction rope is installed at the axis of the rotating shaft.

5. The glass-lined reactor for the production of bulk drugs according to claim 4, characterized in that: Limiting seats rotatably sleeved on the outside of the rotating shaft are symmetrically provided on both sides of the surface of the connecting pipe.

6. The glass-lined reactor for the production of bulk drugs according to claim 1, characterized in that: The ventilation and drying component includes a heating seat arranged on the surface of the kettle cover, the surface of the heating seat is connected to a blower, a filter screen is provided at the air inlet of the blower, and an exhaust pipe is connected between the heating seat and the connecting pipe.

7. The glass-lined reactor for the production of bulk drugs according to claim 6, characterized in that: The filter screen is filled with activated carbon particles, and the heating base is provided with a heating wire.

8. The glass-lined reactor for the production of bulk drugs according to claim 1, characterized in that: The spray ring includes a hollow ring connected between the hoses and the movable sealing rod, the outer peripheral wall of the hollow ring is provided with a plurality of high-pressure nozzles, and the upper surface of the hollow ring is provided with a plurality of L-shaped high-pressure nozzles.

9. The glass-lined reactor for the production of bulk drugs according to claim 1, characterized in that: The kettle cover is provided with an annular sealing placement groove for the spray ring to be placed and sealed.

10. The glass-lined reactor for the production of bulk drugs according to claim 1, characterized in that: A stirring motor is provided on the surface of the kettle cover, and a stirring rod located in the kettle body is installed at the output shaft of the stirring motor.

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