Laboratory mouse fundus blood sampling device

Abstract

The utility model discloses an experimental mouse fundus blood sampling device which comprises a capillary blood sampling tube, an anticoagulation tube and a handheld part, and a plane blood sampling opening is formed in one end of a tube body of the capillary blood sampling tube; a positioning plate is arranged at one end of a pipe body of the anticoagulation pipe, the other end of the pipe body of the capillary blood taking pipe penetrates through the positioning plate and extends into the pipe body of the anticoagulation pipe, and air holes are formed in the side face of a plate body of the positioning plate; the other end of the tube body of the anticoagulation tube is installed on the handheld part, and the handheld part is further provided with an illumination part facing the plane blood taking opening. According to the utility model, all the extruded fundus blood can enter the anticoagulation tube, and the condition that the blood sample is polluted by fallen hair is reduced.

Description

Technical Field

[0001] The utility model relates to the technical field of animal experimental equipment, in particular to a device for collecting fundus blood from experimental mice. Background Art

[0002] The retinal vascular network is the only structure in the circulatory system of small animals, such as lab mice and rabbits, that can be directly and non-invasively observed. The collection and analysis of fundus blood plays a key role in the diagnosis of many ocular and related systemic diseases. Existing fundus blood collection devices for lab mice primarily consist of an anticoagulant tube and a capillary tube. After the lab mouse is anesthetized, the neck is pressed to protrude the eyeball. One end of the capillary tube is inserted into a blood vessel at the inner canthus of the mouse's fundus. The pressure is adjusted to direct the mouse's fundus blood into the capillary tube. The tip of the anticoagulant tube is then aligned with the other end of the tube to collect the fundus blood. Problems with this design include: First, some larger lab mice bleed rapidly during orbital blood collection. Unskilled lab personnel may not be able to collect some of the blood, contaminating clothing. Second, during this process, the mouse's whiskers and hair may fall into the anticoagulant tube, contaminating the blood sample. Therefore, how to develop a new device for collecting fundus blood from experimental mice to overcome the above-mentioned problems in the prior art is a direction that those skilled in the art need to further study. Utility Model Content

[0003] The utility model aims to provide a device for collecting fundus blood from experimental mice, which can ensure that all the squeezed fundus blood enters the anticoagulant tube and reduce the contamination of blood samples by fallen hair.

[0004] The utility model discloses a device for collecting blood from the fundus of an experimental mouse, which comprises:

[0005] A capillary blood collection tube, wherein one end of the capillary blood collection tube is provided with a flat blood collection port;

[0006] An anticoagulation tube, wherein one end of the tube body of the anticoagulation tube is provided with a positioning plate, and the other end of the tube body of the capillary blood collection tube can be detachably passed through the positioning plate and extended into the tube body of the anticoagulation tube, and the positioning plate is made of elastic material;

[0007] A hand-held part, on which the other end of the anticoagulation tube is detachably mounted, and a lighting component is also provided.

[0008] By adopting this technical solution: during the blood collection process, the anticoagulation tube is installed on the handheld part, the other end of the capillary tube is passed through the positioning plate and extended into the tube body of the anticoagulation tube, and the flat blood collection port of the capillary tube is used to collect fundus blood. During the blood collection process, the positioning plate realizes the positioning and sealing of the capillary tube, ensuring that the fundus blood flowing out of the capillary tube flows into the anticoagulation tube. At the same time, it also avoids the problem of the whiskers and hair of the experimental mouse falling into the anticoagulation tube and causing blood sample contamination. In addition, during the blood collection process, if the brightness of the working environment is low, the blood collection lighting can be achieved by using the lighting component to reduce the possibility of operational errors.

[0009] Preferably, the hand-held part includes a cylindrical handle and a control switch, one end of the cylindrical handle is provided with a mounting groove, and the other end of the tube body of the anticoagulation tube can be detachably installed in the mounting groove; the control switch is electrically connected to the lighting component and is used to control the on / off of the lighting component.

[0010] By adopting this technical solution: providing an installation groove to realize the detachable installation of the anticoagulation tube, providing a control switch to realize the lighting control of the lighting component, avoiding the lighting being in a normally on state, and saving energy consumption.

[0011] Preferably, an operating end face is provided at one end of the cylindrical handle, and the mounting groove is arranged at the geometric center position of the operating end face; the lighting component includes a plurality of lighting lamp beads, and the plurality of lighting lamp beads are installed on the operating end face, and the plurality of lighting lamp beads are evenly arranged around the mounting groove on the operating end face; a power supply battery is installed in the cylindrical handle, and the power supply battery is electrically connected to the plurality of lighting lamp beads and is used to power the plurality of lighting lamp beads.

[0012] By adopting this technical solution, the illumination light output by several illumination lamp beads is directed toward the plane blood collection port of the blood collection capillary inserted into the anticoagulant tube, while reducing the shadow caused by the illumination to achieve the best illumination effect.

[0013] Preferably, the hand-held part also includes an arc-shaped handle, both ends of which are fixedly mounted on the cylindrical handle, and the control switch is arranged on the first side wall of the cylindrical handle, and the first side wall is arranged opposite to the arc-shaped inner circle of the arc-shaped handle.

[0014] By adopting this technical solution: during operation, the thumb is inserted between the arc-shaped inner circle of the arc-shaped handle and the first side wall to operate the control switch. At this time, the arc-shaped handle forms a limit on the back of the thumb, making the grip on the handpiece more stable.

[0015] Preferably, a plurality of elastic clamping members are provided in the installation groove, and the distribution positions of the plurality of elastic clamping members are configured to jointly clamp the other end of the tube body of the anticoagulation tube.

[0016] By adopting this technical solution: a plurality of elastic clamping members are used to realize the common clamping of the anticoagulation tube, thereby facilitating the removal of the anticoagulation tube from the handheld part, and realizing the repeated use of the handheld part.

[0017] Compared with the prior art, the utility model has the following advantages:

[0018] Firstly, the utility model can ensure that all the squeezed fundus blood enters the anticoagulation tube and reduce the situation where fallen hair contaminates the blood sample.

[0019] Secondly, the utility model can realize blood collection lighting through the lighting component during the blood collection process, thereby reducing the possibility of operating errors when the ambient brightness is low.

[0020] Finally, the utility model has a simple structure, a convenient operation process, and is easy to prepare and use. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 This is a structural diagram of Example 1. The power supply battery in the handheld part is omitted in this figure due to structural obstruction.

[0022] Figure 2 This is a circuit diagram of the lighting lamp beads.

[0023] In the figure, the component names corresponding to the reference numerals are as follows:

[0024] 100. Capillary blood collection tube; 200. Anticoagulant tube; 300. Handheld part; 400. Power supply battery; 110. Flat blood collection port; 210. Positioning plate; 310. Mounting slot; 320. Elastic clamping part; 330. Arc handle; 340. Column handle; 350. Illuminating lamp bead; 360. Control switch; 341. First side wall. DETAILED DESCRIPTION

[0025] The following describes the embodiments of the present invention through specific examples. Those skilled in the art will readily understand the other advantages and benefits of the present invention from the disclosure herein. The present invention may also be implemented or applied through various other specific embodiments, and the details in this specification may be modified or altered based on different perspectives and applications without departing from the spirit of the present invention.

[0026] Example 1, please refer to Figure 1-2 :

[0027] The utility model discloses a device for collecting blood from the fundus of an experimental mouse, which comprises: a capillary blood collection tube 100, an anticoagulant tube 200, and a handheld part 300.

[0028] The capillary blood sampling tube 100 is used to collect blood from the fundus of the eye, and a flat blood sampling port 110 is provided at one end of the tube body.

[0029] A positioning plate 210 is provided at one end of the tube body of the anticoagulation tube 200, and the other end of the tube body of the capillary blood collection tube 100 can be detachably passed through the positioning plate 210 and extended into the tube body of the anticoagulation tube 200, and the positioning plate 210 is made of elastic material; the other end of the tube body of the anticoagulation tube 200 can be detachably installed on the handheld part 300.

[0030] The handheld portion 300 includes a cylindrical handle 340, an arcuate handle 330, and a control switch 360. A rectangular operating end face is provided at one end of the cylindrical handle 340. A mounting slot 310 is located at the geometric center of the operating end face. Several elastic clamping members 320 are located within the mounting slot 310. These elastic clamping members 320 are arranged to collectively clamp the sidewalls of the anticoagulation tube 200. Several illuminating lamps 350 are also located on the operating end face, evenly distributed around the mounting slot 310. A power supply battery 400 is installed within the cylindrical handle 340 and is electrically connected to the several illuminating lamps 350 for powering them.

[0031] The two ends of the curved handle 330 are fixedly mounted on the cylindrical handle 340. The control switch 360 is disposed on a first sidewall 341 of the cylindrical handle 340, with the first sidewall 341 facing the curved inner circle of the curved handle. The control switch 360 is electrically connected to the lighting component and is used to control the lighting component on / off.

[0032] In practice, the process works as follows:

[0033] The anticoagulation tube 200 is inserted into the mounting slot 310 and mounted on the handheld device 300 using the elastic clamp 320. The other end of the capillary tube 100 is inserted through the positioning plate 210 and into the anticoagulation tube 200. The elastic properties of the positioning plate 210, which has a certain thickness, are used to position and clamp the capillary tube 100. The rat is anesthetized, and the neck is pressed to cause the eyeball to protrude. The illuminating lamp 350 is illuminated, and the flat blood sampling port 110 of the blood sampling capillary tube is inserted into the blood vessel at the inner canthus of the rat's fundus. The pressure is adjusted, and the rat's fundus blood is injected into the blood sampling capillary tube. During the blood collection process, the positioning plate 210 positions and seals the capillary tube 100, ensuring that all fundus blood flowing out of the capillary tube 100 flows into the anticoagulation tube 200. This also prevents contamination of the anticoagulation tube 200 by the rat's whiskers and hair. Furthermore, during the blood collection process, if the working environment is dimly lit, pressing the control switch 360 will simultaneously activate the individual lighting beads 350, providing illumination for blood collection, thereby reducing operational errors caused by the dim environment. After blood collection is complete, the blood collection capillary tube is removed from the anticoagulant tube 200 for centralized disposal. The anticoagulant tube 200 is then removed for testing, and the handheld unit 300 can be reused.

[0034] The embodiments of the present invention are described in detail above with reference to the accompanying drawings, but the present invention is not limited to the above embodiments. Even if various changes are made to the present invention, if these changes fall within the scope of the claims of the present invention and their equivalents, they will still fall within the scope of protection of the present invention.

Claims

1. A device for collecting fundus blood from experimental mice, characterized in that: include: A capillary blood collection tube, wherein one end of the capillary blood collection tube is provided with a flat blood collection port; An anticoagulation tube, wherein one end of the tube body of the anticoagulation tube is provided with a positioning plate, and the other end of the tube body of the capillary blood collection tube can be detachably passed through the positioning plate and extended into the tube body of the anticoagulation tube, and the positioning plate is made of elastic material; A hand-held part, on which the other end of the anticoagulation tube is detachably mounted, and a lighting component is also provided.

2. The device for collecting fundus blood of experimental mice according to claim 1, characterized in that: The handheld part includes a cylindrical handle and a control switch. One end of the cylindrical handle is provided with a mounting groove, and the other end of the anticoagulation tube body is detachably mounted in the mounting groove; the control switch is electrically connected to the lighting component and is used to control the on / off of the lighting component.

3. The device for collecting fundus blood of experimental mice according to claim 2, characterized in that: One end of the cylindrical handle is provided with an operating end surface, and the mounting groove is arranged at the geometric center position of the operating end surface; the lighting component includes a plurality of lighting lamp beads, and the plurality of lighting lamp beads are installed on the operating end surface, and the plurality of lighting lamp beads are evenly arranged on the operating end surface around the mounting groove; A power supply battery is installed in the cylindrical handle, and the power supply battery is electrically connected to the plurality of lighting lamp beads and is used to supply power to the plurality of lighting lamp beads.

4. The device for collecting fundus blood from experimental mice according to claim 3, characterized in that: The hand-held portion also includes an arc-shaped handle, both ends of which are fixedly mounted on the cylindrical handle, and the control switch is arranged on the first side wall of the cylindrical handle, and the first side wall is arranged opposite to the arc-shaped inner circle of the arc-shaped handle.

5. The device for collecting fundus blood from experimental mice according to claim 4, characterized in that: A plurality of elastic clamping members are provided in the installation groove, and the distribution positions of the plurality of elastic clamping members are configured to jointly clamp the other end of the tube body of the anticoagulation tube.

Images