Device convenient for exploring habits of laboratory mice

Abstract

The utility model discloses a device convenient for exploring laboratory mouse habits, which comprises a laboratory mouse habit exploring device, a plurality of independent control cabins are arranged in an upper box body of the laboratory mouse habit exploring device at equal angles, and ventilation openings are arranged above the outer arc-shaped side walls of the independent control cabins in a matched mode. A plurality of independent control cabins are arranged on the experimental mouse habit exploration device, humidity controllers and controllable illuminating lamps are arranged in top covers of the independent control cabins at equal angles, temperature control tubes are arranged at the bottoms of the independent control cabins, the independent control cabins are communicated with the central multi-through groove, the experimental mouse habit exploration device is provided with the independent control cabins, and each independent control cabin can achieve simulation of different environments. In this way, the adaptive capacity of the mouse to the environment can be better explored, different external environments can generate different environmental stimuli to the mouse, the external environments can well induce the animal to generate immune response aiming at the myelin sheath component of the central nervous system (CNS), research data can be well compared, and the research result is more accurate. And the data accuracy is higher.

Description

Technical Field

[0001] This utility model relates to the field of experimental equipment technology, specifically to a device that facilitates the exploration of the habits of laboratory mice. Background Technology

[0002] Immune encephalomyelitis is the most commonly used and recognized animal model for studying multiple sclerosis. It mimics many key pathological features of MS, such as inflammation, demyelination, axonal damage, and neurological dysfunction, by inducing an immune response in animals against the myelin components of their own central nervous system (CNS).

[0003] The core principle of model making:

[0004] It breaks the body's immune tolerance to its own CNS antigens (mainly myelin proteins or their peptides), induces the activation, proliferation and migration of self-reactive T cells (especially Th1 and Th17 cells) to the CNS, triggers an inflammatory cascade, and leads to demyelination and nerve damage.

[0005] Currently, the main method for studying autoimmune encephalomyelitis is the controlled variable method. Such studies are time-consuming, and the data obtained are somewhat biased. Therefore, there is an urgent need for an improved technique to solve this problem in the existing technology. Utility Model Content

[0006] The purpose of this invention is to provide a device that allows each independent control chamber 4 to simulate different environments, thereby better exploring the adaptability of mice to the environment. Moreover, different external environments will produce different environmental stimuli to mice, and the external environment can effectively induce the experimental mouse to produce an immune response against the myelin components of its own central nervous system (CNS), so as to solve the problems mentioned in the background art.

[0007] To achieve the above objectives, this utility model provides the following technical solution: a device for facilitating the exploration of laboratory mouse habits, comprising a laboratory mouse habit exploration device, wherein the laboratory mouse habit exploration device is provided with a box, and multiple independent control chambers are provided at equal angles inside the box, a base is provided at the bottom of the box, the independent control chambers are fixedly installed between the base, a ventilation opening is provided above the outer arc-shaped side wall of the independent control chamber, a connecting slot is provided at the top center of the side wall of the independent control chamber, and a compartment partition is provided between two adjacent independent control chambers;

[0008] The top of the independent control cabin is provided with a top cover, which is transparent and is snapped together with the independent control cabin. The top cover is fan-shaped, and rubber snap joints are provided on the lower surface of the top cover near the edge. Humidity controllers and controllable lights are provided at equal angles inside the top cover, and the humidity controllers and controllable lights are arranged alternately.

[0009] The bottom of the independent control compartment is equipped with a temperature control tube, which is installed in conjunction with the base.

[0010] The experimental mouse behavior exploration device has a central multi-pass slot in the center, and the independent control compartment is connected to the central multi-pass slot.

[0011] Preferably, the main control system is located in the center of the base. The main control system is equipped with a microcontroller, a battery, a network module, a drive module, and a storage module. The battery, network module, drive module, and storage module are respectively connected to the microcontroller. The main control system is equipped with a temperature controller, a light controller, and an oxygen concentration monitoring module. Each independent control compartment is also equipped with a separate temperature controller, light controller, and oxygen concentration monitoring module. The temperature controller, light controller, and oxygen concentration monitoring module are connected to the microcontroller.

[0012] The base has a charging port near its outer wall, which is connected to the battery.

[0013] Preferably, an air pump is provided in the center of the vent, and a dustproof net is provided on the outside of the air pump.

[0014] Preferably, the independent control cabin has a control cabin inlet / outlet located at the bottom of one side, and the control cabin inlet / outlet is connected to the central multi-channel slot.

[0015] Preferably, the central multi-channel groove is a regular hexagonal prism, and a protective mesh cover is provided on the top of the central multi-channel groove.

[0016] Compared with the prior art, the beneficial effects of this utility model are:

[0017] (1) The main control system is used to control the temperature, light, humidity and oxygen in each independent control chamber in real time. The values ​​of temperature, light, humidity and oxygen concentration in each independent control chamber are different. Each independent control chamber simulates an environment and observes the survival status of mice in different independent control chambers.

[0018] (2) A ventilation opening is provided above the external arc-shaped side wall of the independent control cabin. An air pump is provided in the center of the ventilation opening. A dustproof net is provided outside the air pump. The ventilation opening is used to exchange air inside the independent control cabin and ensure the air circulation inside the independent control cabin at a certain time. It not only ensures the air is fresh but also removes odors.

[0019] (3) The top cover is equipped with a humidity controller and a controllable lighting lamp at equal angles. The humidity controller and the controllable lighting lamp are arranged alternately. The humidity controller on the top cover controls the ambient humidity inside the control chamber. The controllable lighting lamp can automatically adjust the intensity and duration of the light to achieve automated control.

[0020] (4) The experimental mouse habit exploration device is equipped with multiple independent control chambers. Each independent control chamber can simulate different environments, which can better explore the mouse's ability to adapt to the environment. Moreover, different external environments will also produce different environmental stimuli to the mice. The external environment can effectively induce the animals to produce immune responses against the myelin components of their own central nervous system (CNS). In this way, the research data can be compared well, and the accuracy of the data is higher. Attached Figure Description

[0021] Figure 1 This is a schematic diagram of the experimental mouse behavior exploration device of this utility model;

[0022] Figure 2 This is a schematic diagram of the main structure of the experimental mouse behavior exploration device of this utility model;

[0023] Figure 3 A top view of the experimental mouse behavior exploration device of this utility model;

[0024] Figure 4 This is a schematic diagram of the internal component distribution structure of the base of this utility model;

[0025] Figure 5 This is a schematic diagram of the bottom component distribution structure of the independent control cabin of this utility model;

[0026] Figure 6 This is a schematic diagram of the top cover structure of this utility model;

[0027] Figure 7 This is a schematic diagram of the hardware structure of the main control system of this utility model.

[0028] In the diagram: 1. Experimental mouse behavior exploration device; 2. Box body; 3. Connecting slot; 4. Independent control chamber; 5. Central multi-channel slot; 6. Chamber partition; 7. Top cover; 8. Protective mesh cover; 9. Base; 10. Charging port; 11. Temperature control tube; 12. Humidity controller; 13. Controllable lighting; 14. Ventilation vent; 15. Main control system; 16. Temperature controller; 17. Light controller; 18. Oxygen concentration monitoring module; 19. Microcontroller; 20. Battery; 21. Network module; 22. Drive module; 23. Storage module; 24. Control chamber entrance / exit. Detailed Implementation

[0029] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0030] Please see Figures 1-7 This utility model provides a technical solution: a device for exploring the habits of laboratory mice, comprising a laboratory mouse habit exploration device 1, a housing 2 on the laboratory mouse habit exploration device 1, multiple independent control chambers 4 arranged at equal angles inside the housing 2, a base 9 at the bottom of the housing 2, the independent control chambers 4 being fixedly installed between the base 9, a main control system 15 located in the center of the base 9, a microcontroller 19, a battery 20, a network module 21, a drive module 22, and a storage module 23 on the main control system 15, the battery 20, network module 21, drive module 22, and storage module 23 being connected to the microcontroller 19 respectively, and the main control system 1... The system 5 is equipped with a temperature controller 16, a light controller 17, and an oxygen concentration monitoring module 18. Each independent control chamber 4 is also equipped with its own temperature controller 16, light controller 17, and oxygen concentration monitoring module 18. The temperature controller 16, light controller 17, and oxygen concentration monitoring module 18 are connected to the microcontroller 19. The main control system 15 is used to control the temperature, light, humidity, and oxygen inside each independent control chamber 4 in real time. The values ​​of temperature, light, humidity, and oxygen concentration inside each independent control chamber 4 are different. Each independent control chamber 4 simulates an environment, and the survival status of mice inside different independent control chambers 4 is observed.

[0031] The base 9 has a charging port 10 near the outer wall. The charging port 10 is connected to the battery 20. The charging port 10 charges the battery 20. The battery 20 is used as a backup power source in case of power failure, ensuring that the equipment can still operate normally when the external power supply is interrupted.

[0032] The independent control compartment 4 has a ventilation opening 14 above the external arc-shaped side wall. An air pump is located in the center of the ventilation opening 14, and a dustproof net is installed outside the air pump. The ventilation opening 14 is used to exchange air inside the independent control compartment 4 and ensure the circulation of air inside the independent control compartment 4 at a certain time. It not only ensures the freshness of the air but also removes odors.

[0033] The top center of the side wall of the independent control cabin 4 is provided with a connecting slot 3. A cabin partition 6 is provided between two adjacent independent control cabins 4. The top of the independent control cabin 4 is provided with a top cover 7, which is a transparent top cover. The top cover 7 is snapped onto the independent control cabin 4. The top cover 7 is provided with a humidity controller 12 and a controllable light 13 at equal angles inside. The humidity controller 12 and the controllable light 13 are arranged alternately. The humidity controller 12 on the top cover 7 controls the ambient humidity inside the control cabin. The controllable light 13 can automatically adjust the intensity and duration of the light to achieve automated control.

[0034] The top cover 7 is fan-shaped, and rubber snap joints are provided on the lower surface of the top cover 7 near the edge. The top cover 7 is connected to the connecting slot 3 in the center of the top of the side wall of the independent control cabin 4 through the rubber snap joints on the lower surface, so that the top cover 7 and the independent control cabin 4 are sealed and connected to prevent the external environment from affecting the interior of the independent control cabin 4.

[0035] The bottom of the independent control chamber 4 is equipped with a temperature control tube 11, which is installed in conjunction with the base 9. The temperature control tube 11 controls the temperature inside the entire independent control chamber 4 and can automatically adjust the controlled temperature range according to experimental requirements, making it convenient to simulate different temperature environments. The bottom side of the independent control chamber 4 is equipped with a control chamber inlet and outlet 24, which is connected to the central multi-pass slot 5.

[0036] The experimental mouse behavior exploration device 1 has a central multi-passage slot 5 in the center. The independent control chamber 4 is connected to the central multi-passage slot 5. When conducting experiments on the experimental mouse, the door of one of the independent control chambers 4 is opened and the experimental mouse is placed inside the central multi-passage slot 5. The experimental mouse will automatically enter the independent control chamber 4 with the door open. The central multi-passage slot 5 is a regular hexagonal prism and the top of the central multi-passage slot 5 is equipped with a protective net cover 8.

[0037] Example 1,

[0038] The experimental mouse behavior exploration device 1 has multiple independent control chambers 4. The temperature, light, humidity and oxygen concentration inside each independent control chamber 4 are adjusted according to the needs of the experiment, so that the environment inside each independent control chamber 4 is different. A mouse is selected for experimental observation and placed in the central multi-channel 5. At first, the mouse will randomly crawl into one of the independent control chambers 4. Over time, the experimental mouse will enter and exit different independent control chambers 4. After long-term observation, the experimental mouse will eventually stay in its favorite environment for a long time, thus obtaining the most suitable environment for the mouse to live in.

[0039] Example 2,

[0040] The experimental mouse behavior exploration device 1 contains multiple independent control chambers 4. The temperature, light, humidity, and oxygen concentration inside each independent control chamber 4 are adjusted according to the needs of the experiment, so that the environment inside each independent control chamber 4 is different. Six mice are selected for experimental observation, and one mouse is placed in each independent control chamber 4. Over time, various functions of the mice in different independent control chambers 4 are tested to detect the effect of different external environments on the immune response of the myelin components of the experimental mice's central nervous system (CNS).

[0041] The experimental mouse behavior exploration device 1 is equipped with multiple independent control chambers 4. Each independent control chamber 4 can simulate different environments, which can better explore the mouse's ability to adapt to the environment. Moreover, different external environments will also produce different environmental stimuli to the mice. The external environment can effectively induce the animals to produce an immune response against the myelin sheath components of their own central nervous system (CNS). In this way, the research data can be compared well, and the accuracy of the data is higher.

[0042] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A device for facilitating the exploration of laboratory mouse habits, comprising a laboratory mouse habit exploration device (1), characterized in that: The experimental mouse behavior exploration device (1) is equipped with a box (2), and multiple independent control chambers (4) are provided at equal angles inside the box (2). The bottom of the box (2) is provided with a base (9). The independent control chambers (4) are fixedly installed with the base (9). The upper part of the outer arc-shaped side wall of the independent control chamber (4) is provided with a ventilation opening (14). The top center of the side wall of the independent control chamber (4) is provided with a connecting slot (3). A compartment partition (6) is provided between two adjacent independent control chambers (4). The top of the independent control cabin (4) is provided with a top cover (7), which is a transparent top cover. The top cover (7) is snapped together with the independent control cabin (4). The top cover (7) is fan-shaped. Rubber snap joints are provided on the lower surface of the top cover (7) near the edge. Humidity controller (12) and controllable lighting lamp (13) are provided at equal angles inside the top cover (7). The humidity controller (12) and controllable lighting lamp (13) are arranged alternately. The bottom of the independent control compartment (4) is provided with a temperature control tube (11), which is installed in conjunction with the base (9); The experimental mouse behavior exploration device (1) has a central multi-channel slot (5) in the center, and the independent control cabin (4) is connected to the central multi-channel slot (5).

2. The device for facilitating the exploration of laboratory mouse habits according to claim 1, characterized in that: The base (9) has a main control system (15) in the center. The main control system (15) is equipped with a microcontroller (19), a battery (20), a network module (21), a drive module (22), and a storage module (23). The battery (20), network module (21), drive module (22), and storage module (23) are connected to the microcontroller (19). The main control system (15) is equipped with a temperature controller (16), a light controller (17), and an oxygen concentration monitoring module (18). Each independent control compartment (4) is equipped with a temperature controller (16), a light controller (17), and an oxygen concentration monitoring module (18). The temperature controller (16), light controller (17), and oxygen concentration monitoring module (18) are connected to the microcontroller (19). The base (9) has a charging port (10) near its outer wall, which is connected to the battery (20).

3. The device for facilitating the exploration of laboratory mouse habits according to claim 1, characterized in that: An air pump is provided in the center of the vent (14), and a dustproof net is provided on the outside of the air pump.

4. The device for facilitating the exploration of laboratory mouse habits according to claim 1, characterized in that: The independent control cabin (4) is provided with a control cabin inlet / outlet (24) at the bottom of one side, and the control cabin inlet / outlet (24) is connected to the central multi-channel slot (5).

5. The device for facilitating the exploration of laboratory mouse habits according to claim 1, characterized in that: The central multi-pass groove (5) is a regular hexagonal prism, and a protective mesh cover (8) is provided on the top of the central multi-pass groove (5).

Images