Reagent classification device for radiotherapeutic drug toxicology experiment

The elastic plastic placement plate and clamping and fixing components solve the problem that the existing device can only place reagent tubes of the same size, and achieve stable clamping and radiation protection of reagent tubes of different sizes, ensuring the safety of the experiment.

CN223439906UActive Publication Date: 2025-10-17JIANGSU PROVINCIAL INSTITUTE OF MATERIA MEDICA CO LTD
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Patent Information

Application Number
CN202422796572.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-11-18
Publication Date
2025-10-17
Estimated Expiration
2034-11-18

AI Technical Summary

Technical Problem

Existing reagent sorting devices can only accommodate drug reagent tubes of the same size and cannot adapt to reagent tubes of different sizes, resulting in limitations.

Method used

An elastic plastic placement plate and a clamping fixing component are used. The small holes of the elastic plastic placement plate are expanded to accommodate reagent tubes of different sizes, and the reagent tubes are clamped by the elastic force of the compression spring and the clamping plate. In combination with the isolation sleeve and the shielding cover, additional radiation protection is provided.

Benefits of technology

It achieves stable clamping of reagent tubes of different sizes, avoids experimental errors caused by shaking, reduces the risk of radiation leakage, provides a physical protection layer, and prevents the spread of radioactive substances.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a radioactive therapeutic drug toxicology experiment reagent classification device, which comprises a reagent placing box and a clamping and fixing assembly, a fixing plate and an elastic plastic placing plate are placed in the reagent placing box, small holes are arranged in the elastic plastic placing plate, and the clamping and fixing assembly is connected with the fixing plate. A reagent tube is placed in a small hole of the elastic plastic placing plate, a first clamping plate and a second clamping plate are clamped and fixed to the outer side of the reagent tube in a contact mode, and the small hole of the elastic plastic placing plate can be expanded through the elastic plastic placing plate and the clamping and fixing assembly to effectively adapt to reagent tubes of different sizes. The device can fix test tubes of various specifications, the first clamping plate and the second clamping plate can make close contact and clamp reagent tubes through the elastic force and the extrusion effect of the compression spring, and experiment errors or accidents caused by shaking of the test tubes are avoided; the reagent tube placing box can be used for effectively placing, clamping and fixing reagent tubes with different sizes.
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Description

TECHNICAL FIELD

[0001] The utility model relates to reagent classification device technical field, concretely is a reagent classification device for radiotherapy drug toxicology experiment. BACKGROUND

[0002] The reagent classification device for radiotherapy drug toxicology experiment is specially used for managing and classifying chemical reagents and radioactive substances for radiotherapy drug toxicology research, and due to the involvement of radioactive substances, such devices must have high safety, and they usually include lead or other heavy metal shielding materials, and in the development stage of new drugs, especially radioactive drugs, a large number of toxicology tests need to be carried out to evaluate their safety and effectiveness.

[0003] In the prior art, a reagent classification and placement device is disclosed, which comprises a placement block cover plate, the placement block is slidably connected with the cover plate, a plurality of placement grooves are formed in the upper end of the placement block, a first clamping plate is fixedly connected in the placement groove, a second clamping plate is slidably connected in the placement groove, two device cavities are formed in the placement block, a plurality of sliding grooves are formed in the wall of the device cavity, the number of the sliding grooves is twice the number of the placement grooves, a connecting rod is slidably connected in the sliding groove, the connecting rod is fixedly connected with the second clamping plate, a sliding mechanism is installed in the device cavity to slide the connecting rod, the sliding mechanism comprises a lead screw sleeve slidably connected in the device cavity, the connecting rod is fixedly connected to the outer wall of the lead screw sleeve, a plurality of reciprocating lead screws are rotatably connected in the device cavity, the number of the reciprocating lead screws is consistent with the number of the placement grooves, and the lead screw sleeve is threadedly connected to the threaded section of the reciprocating lead screw.

[0004] In the scheme, the reciprocating lead screw is rotated in the lead screw sleeve, which further drives the clamping plate to move in the placement groove, but the clamping plate of the placement groove will move and clamp at the same time, and a plurality of drug test tubes will be clamped, which may cause the reagent classification device to be able to place only drug reagent tubes with the same size, and cannot place drug test tubes of different sizes, resulting in the limitation of the reagent classification device. UTILITY MODEL CONTENTS

[0005] The utility model aims at providing a reagent classification device for radiotherapy drug toxicology experiment to solve the problems in the above background technology.

[0006] To achieve the above object, the utility model provides the following technical scheme: a reagent classification device for radiotherapy drug toxicology experiment, including reagent placing box and clamping fixing assembly, characterized by: the inside of reagent placing box is placed with fixed plate and elastic plastic placing plate, the inside of elastic plastic placing plate is equipped with small hole, the small hole of elastic plastic placing plate is placed with reagent tube, the outside of reagent tube is contacted and clamped with first clamping plate and second clamping plate, the outside of first clamping plate and second clamping plate is equipped with rubber pad, and one end of first clamping plate and second clamping plate is connected and fixed with telescopic rod through bolt.

[0007] As further preferred of the technical scheme, one end of the telescopic rod is connected and fixed with the compression spring through screw, and one end of the compression spring is connected in the telescopic cylinder through screw.

[0008] As further preferred of the technical scheme, the telescopic cylinder is connected in the through hole of the clamping mounting block through bolt, the upper end of the clamping mounting block is equipped with sliding groove, and the lower end of the clamping mounting block is connected in the upper end of the fixed plate through bolt.

[0009] As further preferred of the technical scheme, the sliding groove is slidably connected with the sliding block, and the upper end of the sliding block is fixedly installed with the handle.

[0010] As further preferred of the technical scheme, the outside of the reagent tube is sleeved with the isolation sleeve, and the isolation sleeve is inserted in the elastic plastic placing plate.

[0011] As further preferred of the technical scheme, the upper end of the reagent placing box is equipped with the moving groove on both sides, and the moving groove is slidably connected with the moving rod.

[0012] As further preferred of the technical scheme, the upper end of the moving rod is connected and fixed with the shielding cover plate through bolt, and the upper end of the shielding cover plate is installed with the handle.

[0013] The utility model provides a reagent classification device for radiotherapy drug toxicology experiment has the following beneficial effects:

[0014] (1) the utility model discloses through elastic plastic placing plate and clamping fixing assembly, the small hole of elastic plastic placing plate can expand, effectively adapt to the reagent tube of different sizes, so that the device can fix the test tube of multiple specifications, through the elasticity and extrusion effect of compression spring, the first clamping plate and the second clamping plate can tightly contact and clamp reagent tube, avoid the experimental error or accident caused by test tube shaking, and the reagent tube placing box can effectively place and clamp and fix different size reagent tubes.

[0015] (2)The utility model discloses a isolation sleeve and shielding cover plate can effectively reduce the influence of the radiation of the radioactive medicine reagent tube in the reagent tube on the surrounding environment and personnel, and the isolation sleeve and the shielding cover plate provide an additional physical protection layer for the radioactive medicine reagent tube to prevent the tube from being broken or leaking accidentally, thereby avoiding the diffusion of radioactive substances. BRIEF DESCRIPTION OF DRAWINGS

[0016] Figure 1 It is the schematic diagram of the whole structure of the utility model;

[0017] Figure 2 It is the schematic diagram of the clamping fixing assembly structure of the utility model;

[0018] Figure 3 It is the schematic diagram of the isolation sleeve and the elastic plastic placing plate structure of the utility model;

[0019] Figure 4 It is the schematic diagram of the clamping plate and the clamping mounting block structure of the utility model;

[0020] Figure 5 It is the schematic diagram of the clamping fixing assembly split structure of the utility model;

[0021] In the drawing: 100, reagent placing box;101, shielding cover plate;102, handle;103, moving rod;104, moving groove;107, reagent tube;108, elastic plastic placing plate;109, fixed plate;110, isolation sleeve;200, clamping fixing assembly;201, clamping mounting block;202, sliding groove;203, first clamping plate;204, second clamping plate;205, telescopic cylinder;206, compression spring;207, telescopic rod;208, sliding block;209, handle. DETAILED DESCRIPTION

[0022] The technical scheme in the embodiments of the utility model will be described clearly and completely in combination with the drawings in the embodiments of the utility model.

[0023] The utility model provides technical scheme: such as Figures 1-2 、 Figures 4-5As shown in the embodiment, the reagent classification device for radiopharmaceutical toxicology experiment includes a reagent placing box 100 and a clamping fixing assembly 200. A fixed plate 109 and an elastic plastic placing plate 108 are placed in the reagent placing box 100. The fixed plate 109 is screwed in the inside of the reagent placing box 100. The elastic plastic placing plate 108 is fixed in the inside of the reagent placing box 100 by colloid. The elastic plastic placing plate 108 is made of elastic plastic material. Small holes are arranged in the inside of the elastic plastic placing plate 108. Reagent tubes 107 are placed in the small holes of the elastic plastic placing plate 108. Different sizes of reagent tubes 107 are inserted through the small holes in the inside of the elastic plastic placing plate 108. The small holes of the elastic plastic placing plate 108 are expanded. When the test tubes are placed in the small holes, the inside of the elastic plastic placing plate 108 is contracted and tightened. The outside of the reagent tubes 107 is in contact with first clamping plates 203 and second clamping plates 204. Rubber pads are arranged on the outside of the first clamping plates 203 and the second clamping plates 204. The rubber pads are in contact with the outside of the reagent tubes 107. One end of the first clamping plates 203 and the second clamping plates 204 is connected and fixed with a telescopic rod 207 through a bolt. One end of the telescopic rod 207 is connected and fixed with a compression spring 206 through a screw. One end of the compression spring 206 is connected in the inside of a telescopic cylinder 205 through a screw. The telescopic cylinder 205 is connected in the through hole in the inside of a clamping mounting block 201 through a bolt. A sliding groove 202 is arranged in the upper end of the clamping mounting block 201. The lower end of the clamping mounting block 201 is connected with the upper end of the fixed plate 109 through a bolt. A sliding block 208 is slidably connected in the inside of the sliding groove 202. The sliding block 208 can move in the sliding groove 202. A handle 209 is fixedly installed on the upper end of the sliding block 208. In actual use, first, different sizes of reagent tubes 107 are inserted through the small holes in the inside of the elastic plastic placing plate 108. The small holes of the elastic plastic placing plate 108 are expanded. When the test tubes are placed in the small holes, the inside of the elastic plastic placing plate 108 is contracted and tightened. Then, the handle 209 is moved by the operator to drive the sliding block 208 to move in the sliding groove 202, thereby driving the telescopic rod 207 to move in the telescopic cylinder 205. The compression spring 206 is compressed. When the reagent tubes 107 are clamped and fixed, the operator only needs to support and slowly move the handle 209. The telescopic rod 207 is driven to move outward in the telescopic cylinder 205 by the elastic force and extrusion of the compression spring 206, thereby further driving the first clamping plates 203 and the second clamping plates 204 to move and clamp the reagent tubes 107. Different sizes of reagent tubes 107 can be effectively placed and clamped and fixed.

[0024] Through the elastic plastic placement plate 108 and the clamping and fixing assembly 200, the small hole of the elastic plastic placement plate 108 can be expanded, effectively adapting to different sizes of reagent tubes 107, so that the device can fix reagent tubes of various specifications. Through the elastic force and extrusion effect of the compression spring 206, the first clamping plate 203 and the second clamping plate 204 can tightly contact and clamp the reagent tube 107, avoiding experimental errors or accidents caused by shaking of the test tube. The reagent tube placement box can effectively place and clamp and fix different sizes of reagent tubes 107.

[0025] As shown in Figures 1-3 The outer side of the reagent tube 107 is sleeved with a isolation sleeve 110, which is inserted into the inside of the elastic plastic placement plate 108. The upper end of the reagent placement box 100 is provided with a moving groove 104 on both sides, and the inside of the moving groove 104 is slidably connected with a moving rod 103. The upper end of the moving rod 103 is connected and fixed with the shielding cover plate 101 through a bolt. The upper end of the shielding cover plate 101 is provided with a handle 102. In actual use, the operator inserts the radioactive drug reagent tube 107 into the corresponding isolation sleeve 110, and then inserts the isolation sleeve 110 into the inside of the elastic plastic placement plate 108. Then, the moving rod 103 is slid in the moving groove 104, which drives the shielding cover plate 101 to move, so as to cover and close the reagent placement box 100. The materials of the isolation sleeve 110 and the shielding cover plate 101 are usually lead, tungsten alloy or other high-density materials. These materials are widely used in the storage and transportation of radioactive substances due to their excellent radiation shielding performance. Lead is a commonly used radiation shielding material because it has good absorption capacity for gamma rays and X-rays. Tungsten alloy has high density and excellent mechanical properties, and performs well in applications that require higher strength and smaller size.

[0026] Through the isolation sleeve 110 and the shielding cover plate 101, the influence of the radiation released by the drug in the reagent tube 107 on the surrounding environment and personnel can be effectively reduced. The isolation sleeve 110 and the shielding cover plate 101 provide an additional physical protection layer for the radioactive drug reagent tube 107, preventing accidental breakage or leakage of the test tube, thereby avoiding the diffusion of radioactive substances.

[0027] The utility model provides a reagent classification device for radioactive treatment drug toxicology experiment, specific working principle is as follows: reagent classification device for radioactive treatment drug toxicology experiment mainly classifies based on the characteristic of radioactive nuclide and the mechanism of action of drug. Different radioactive nuclide has different decay type (such as alpha, beta, gamma ray or auger electron), and these characteristics determine their biological effect and penetration ability in vivo. The device classifies reagents into different categories by recognizing these characteristics, and the operator inserts the radioactive reagent tube 107 into the appropriate isolation sleeve 110, then places the isolation sleeve 110 inside the elastic plastic placement plate 108, then inserts the reagent tube 107 of different sizes through the small hole in the elastic plastic placement plate 108, the small hole in the elastic plastic placement plate 108 expands, and when the test tube is placed in the small hole, the inside of the elastic plastic placement plate 108 contracts, then the operator moves the handle 209, drives the sliding block 208 to move inside the sliding groove 202, and further drives the telescopic rod 207 to move inside the telescopic cylinder 205, the compression spring 206 is compressed, when clamping and fixing the reagent tube 107, the operator only needs to hold the handle 209 and move slowly, the elastic force of the compression spring 206 and the extrusion effect drive the telescopic rod 207 to move outward inside the telescopic cylinder 205, further drive the first clamping plate 203 and the second clamping plate 204 to move and contact and clamp the reagent tube 107, which can effectively place and clamp and fix the reagent tube 107 of different sizes.

[0028] Although the embodiments of the utility model have been shown and described, it can be understood by those skilled in the art that various changes, modifications, replacements and variations can be made to these embodiments without departing from the principles and spirits of the utility model, and the scope of the utility model is defined by the appended claims and their equivalents.

Claims

1. A reagent sorting device for radioactive therapeutic drug toxicology experiments, comprising a reagent placement box (100) and a clamping and fixing assembly (200), characterized in that: A fixing plate (109) and an elastic plastic placement plate (108) are placed inside the reagent placement box (100), a small hole is provided inside the elastic plastic placement plate (108), a reagent tube (107) is placed in the small hole of the elastic plastic placement plate (108), the outer side of the reagent tube (107) is contacted and clamped with a first clamping plate (203) and a second clamping plate (204), the outer sides of the first clamping plate (203) and the second clamping plate (204) are provided with rubber pads, and one end of the first clamping plate (203) and the second clamping plate (204) are connected and fixed to the telescopic rod (207) by bolts.

2. The reagent sorting device for radioactive therapeutic drug toxicology experiments according to claim 1, characterized in that: One end of the telescopic rod (207) is connected and fixed to the compression spring (206) via a screw, and one end of the compression spring (206) is connected to the inside of the telescopic cylinder (205) via a screw.

3. The reagent sorting device for radioactive therapeutic drug toxicology experiments according to claim 2, characterized in that: The telescopic cylinder (205) is connected to the internal through hole of the clamping mounting block (201) by means of bolts. A sliding groove (202) is provided inside the upper end of the clamping mounting block (201). The lower end of the clamping mounting block (201) is connected to the upper end of the fixing plate (109) by means of bolts.

4. The reagent sorting device for radioactive therapeutic drug toxicology experiments according to claim 3, characterized in that: A sliding block (208) is slidably connected inside the sliding groove (202), and a handle (209) is fixedly mounted on the upper end of the sliding block (208).

5. The reagent sorting device for radioactive therapeutic drug toxicology experiments according to claim 1, characterized in that: The outer side of the reagent tube (107) is sleeved with an isolation sleeve (110), and the isolation sleeve (110) is inserted into the interior of the elastic plastic placement plate (108).

6. The reagent sorting device for radioactive therapeutic drug toxicology experiments according to claim 1, characterized in that: Both sides of the upper end of the reagent placement box (100) are provided with moving grooves (104), and the interior of the moving grooves (104) is slidably connected with a moving rod (103).

7. The reagent sorting device for radioactive therapeutic drug toxicology experiments according to claim 6, characterized in that: The upper end of the moving rod (103) is connected and fixed to the shielding cover (101) by means of bolts, and a handle (102) is installed on the upper end of the shielding cover (101).