Automatic embedding device of tissue dehydrator
By integrating the dehydration and embedding functions into the tissue dehydrator and designing an automatic embedding device, the problem that existing equipment cannot handle both simultaneously is solved, the entire process is automated, work efficiency and safety are improved, and reagent volatilization and medical accidents are reduced.
Patent Information
- Application Number
- CN202422405093.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-04
- Publication Date
- 2025-10-24
- Estimated Expiration
- 2034-10-04
AI Technical Summary
Existing automated equipment can only complete tissue dehydration or tissue embedding independently, resulting in high equipment procurement and maintenance costs, requiring manual intervention, increasing the complexity of the workflow and the risk of medical accidents, and reagent volatilization is harmful to the environment and health.
An automatic embedding device for a tissue dehydrator is designed, integrating the dehydration and embedding functions in the same device. The transmission mechanism and fixed support structure are used to achieve full-process automation. Electromagnets and a mechanical crane are used to transfer and position samples, ensuring accurate sample identification between different steps and reducing reagent volatilization.
The full process of paraffin sectioning of biological tissue samples has been automated, which improves work efficiency, reduces manual intervention and reagent volatilization, ensures the accuracy of sample identification, and reduces the possibility of medical accidents and environmental pollution risks.
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Figure CN223470864U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to a device for making paraffin sections of biological tissue specimens, in particular to an automatic embedding device of a tissue dehydrator, which is widely used in the fields of medical clinical pathology, cytological examination and biological research. Background Art
[0002] In existing technology, the paraffin sectioning process for biological tissue samples primarily involves two steps: tissue dehydration and tissue embedding. While the term "tissue dehydration" is often used in the industry to abbreviate this process, it actually encompasses both tissue dehydration and tissue clearing. Currently, most companies, both domestically and internationally, have developed automated tissue dehydrators and automated tissue embedding machines for these two steps, respectively, to meet the processing needs of biological tissue samples.
[0003] However, most existing automated equipment can only perform tissue dehydration or tissue embedding independently; there is no device in the domestic market that can handle both steps simultaneously. Lab technicians often need to operate two devices to complete tissue sample processing, which not only increases equipment procurement and maintenance costs but also requires manual intervention to connect the two steps, reducing work efficiency.
[0004] Furthermore, switching between two independent processes can lead to misidentification of tissue samples or confusion in labeling, potentially causing medical accidents. Furthermore, switching between independent devices can easily lead to reagent volatilization, increasing environmental pollution and potentially impacting air quality and worker health. Therefore, developing a fully automated device capable of dehydrating and embedding tissues is crucial and urgent. Summary of the Invention
[0005] In order to solve the problems existing in the prior art, the utility model provides an automatic embedding device for a tissue dehydrator, which realizes the full process automation of paraffin section wax block production of biological tissue samples by integrating dehydration and embedding functions.
[0006] The purpose of this utility model is achieved through the following technical solutions:
[0007] An automatic embedding device for a tissue dehydrator comprises a wax dipping cylinder component, an embedding wax cylinder component, a transmission mechanism component and a fixed support structure.
[0008] Preferably, the wax dipping cylinder assembly includes a wax dipping cylinder body, a cylinder cover, a heating plate located at the bottom of the cylinder, and a cylinder valve.
[0009] As preferred, the embedding wax jar assembly comprises an embedding wax jar body, a heating plate of the jar bottom, a heating plate terminal post, a jar valve, an embedding wax jar cover, a jar cover rotating shaft, a jar cover rotating shaft buckle, a jar cover rotating shaft gear, a specimen basket holder and a specimen basket holder fixing seat; wherein the embedding wax jar cover is provided with an electromagnet and a jar cover lock buckle hole, and the embedding wax jar cover is connected with the upper edge of one side of the embedding wax jar body through the jar cover rotating shaft buckle and the jar cover rotating shaft and can rotate 90 degrees around the jar cover rotating shaft.
[0010] As preferred, the embedding wax jar cover and the specimen basket holder fixing seat are jointly connected on the jar cover rotating shaft and can freely move, and the specimen basket holder fixing seat passes through the jar cover lock buckle hole of the embedding wax jar cover through the specimen basket holder fixing seat lock buckle and is locked by the electromagnet.
[0011] As preferred, the specimen basket holder is provided with double handles and is movably arranged on the specimen basket holder fixing seat, the specimen basket is movably arranged on the specimen basket holder, and the specimen basket is provided with a handle.
[0012] As preferred, the transmission mechanism assembly comprises a motor and a motor gear, and the motor is engaged with the jar cover rotating shaft gear through the motor gear to drive the jar cover rotating shaft to rotate 90 degrees for opening and closing operation of the embedding wax jar cover.
[0013] As preferred, the fixed support structure comprises a heating plate, a jar body fixing member and a motor fixing member.
[0014] As preferred, the specimen basket is vertically placed with the tissue embedding boxes in layers or columns, and the specimen basket is moved between the reagent jars, the wax immersion jars and the embedding wax jars of the tissue dehydrator by the mechanical hoist arm of the tissue dehydrator through the specimen basket handle.
[0015] As preferred, when the embedding wax jar cover is in the 90-degree open state, the specimen basket is moved into the specimen basket holder of the embedding wax jar cover from the wax immersion jar by the mechanical hoist arm of the tissue dehydrator, and the specimen basket holder fixing seat lock buckle passes through the jar cover lock buckle hole of the embedding wax jar cover and is locked by the electromagnet; at this time, the tissue embedding boxes in the specimen basket remain in a vertical state, and the liquid reagent and the molten paraffin can freely flow into and out of the tissue embedding boxes; when the embedding wax jar cover is closed, the specimen basket holder fixing seat and the specimen basket holder together with the specimen basket therein are rotated 90 degrees with the embedding wax jar cover, and the tissue embedding boxes in the specimen basket also become horizontal, so that the molten paraffin fills the tissue embedding boxes.
[0016] As preferred, when the specimen basket fixing seat passes through the cylinder cover lock hole of the embedding wax cylinder cover through the specimen basket fixing seat lock buckle and is unlocked by the electromagnet, the embedding wax cylinder cover is automatically opened, and the specimen basket fixing seat and the specimen basket together with the specimen basket in it are separated from the embedding wax cylinder cover; at this time, the specimen basket and the specimen basket in it are placed on the specimen basket fixing seat in a horizontal state, and the tissue embedding box in the specimen basket remains in a horizontal state; the mechanical arm of the tissue dehydrator moves the specimen basket and the specimen basket in it out of the embedding wax cylinder through the double handles of the specimen basket, and then the mechanical arm of the tissue dehydrator places the specimen basket in the storage position.
[0017] The utility model has the following advantages:
[0018] 1. Full-process automation: by integrating the tissue dehydration and embedding steps in the same device, manual intervention is reduced, greatly improving work efficiency.
[0019] 2. Reduce reagent evaporation: since the sample no longer needs to be transferred between two devices, the amount of reagent evaporation is greatly reduced, thereby reducing the harm to the environment and the operating personnel.
[0020] 3. Improve sample identification accuracy: through integrated design, the sample label confusion between dehydration and embedding is avoided, ensuring the identification accuracy of the sample and reducing the possibility of medical accidents. BRIEF DESCRIPTION OF DRAWINGS
[0021] Figure 1 : The structure perspective view of the device of the utility model.
[0022] Figure 2 : The structure perspective view of the device of the utility model in the open cover state.
[0023] Figure 3 : The front view of the device of the utility model in the open cover state.
[0024] Figure 4 : The embedding wax cylinder cover and specimen basket fixing seat structure perspective view of the device of the utility model.
[0025] Figure 5 : The structure perspective view of the specimen basket in the vertical state when the device of the utility model is opened.
[0026] Figure 6 : The structure perspective view of the specimen basket in the horizontal state when the device of the utility model is opened.
[0027] Explanation of reference numerals in the drawings:
[0028] 1. Wax immersion cylinder, 2. Embedding wax cylinder, 3. Embedding wax cylinder cover, 4. Heating plate, 5. Heating plate terminal, 6. Electromagnet, 7. Cylinder cover shaft gear, 8. Motor, 9. Motor gear, 10. Motor fixing part, 11. Heating plate and cylinder body fixing part, 12. Specimen basket, 13. Specimen basket double handles, 14. Specimen basket fixing seat, 15. Cylinder cover shaft, 16. Cylinder cover shaft buckle, 17. Specimen basket fixing seat lock, 18. Cylinder valve, 19. Specimen basket handle, 20. Specimen basket, 21. Tissue embedding cassette, 22. Cylinder cover lock hole. DETAILED DESCRIPTION
[0029] The following describes the specific embodiments of the present invention in detail with reference to the accompanying drawings. It should be noted that the description of these embodiments is only used to help understand the present invention and does not limit it. In addition, the technical features in the various embodiments described herein can be combined in any way without conflict.
[0030] The specific implementation of the present invention will be described in detail below with reference to the accompanying drawings.
[0031] Example 1: The structure of the automatic embedding device of the tissue dehydrator of the present invention is as follows Figures 1 to 6 As shown, it mainly includes a wax immersion cylinder assembly, an embedding wax cylinder assembly, a transmission mechanism assembly and a fixed support structure.
[0032] The wax dipping cylinder assembly includes a wax dipping cylinder body 1 , a cylinder cover, a heating plate 4 located at the bottom of the cylinder, and a cylinder valve 18 .
[0033] The embedding wax cylinder assembly includes an embedding wax cylinder body 2, a heating plate 4 at the bottom of the cylinder, a heating plate terminal 5, a cylinder valve 18, an embedding wax cylinder cover 3, a cylinder cover rotating shaft 15, a cylinder cover rotating shaft buckle 16, a cylinder cover rotating shaft gear 7, a specimen basket 12 and a specimen basket fixing seat 14; wherein, the embedding wax cylinder cover 3 is provided with an electromagnet 6 and a cylinder cover locking hole 22, and the embedding wax cylinder cover 3 is connected to the upper edge of one side of the embedding wax cylinder body 2 through the cylinder cover rotating shaft buckle 16 and the cylinder cover rotating shaft 15, and can rotate 90 degrees around the cylinder cover rotating shaft 15.
[0034] The embedding wax cylinder cover 3 and the specimen basket holder 14 are connected to the cylinder cover rotating shaft 15 and can move freely. The specimen basket holder 14 passes through the cylinder cover locking hole 22 of the embedding wax cylinder cover 3 through the specimen basket holder locking seat 17 and is locked by the electromagnet 6.
[0035] The specimen basket 12 is provided with double handles 13 and can be movably placed on the specimen basket fixing seat 14 . The specimen basket 20 can be movably placed on the specimen basket 12 , and the specimen basket 20 is provided with handles 19 .
[0036] The transmission mechanism assembly comprises a motor 8 and a motor gear 9, the motor 8 is engaged with the cylinder cover rotating shaft gear 7 through the motor gear 9, so as to drive the cylinder cover rotating shaft 15 to rotate the embedding wax cylinder cover 3 by 90 degrees to carry out opening and closing operation.
[0037] The fixed support structure comprises a heating plate, a cylinder fixing part 11 and a motor fixing part 10.
[0038] The specimen basket 20 is vertically placed in layers or in rows, and the tissue embedding boxes 21 are arranged in the specimen basket 20; the specimen basket 20 is moved between the reagent cylinders and the embedding wax cylinders 2 of the tissue dehydrator by the mechanical arm of the tissue dehydrator through the specimen basket handle 19.
[0039] The working principle of the automatic embedding device of the tissue dehydrator is as follows:
[0040] When the embedding wax cylinder cover 3 is in the 90-degree opening state, the specimen basket 20 is moved into the specimen basket rack 12 of the embedding wax cylinder cover 3 from the wax immersion cylinder 1 through the mechanical arm of the tissue dehydrator, the specimen basket rack fixing seat lock catch 17 passes through the cylinder cover lock catch hole 22 of the embedding wax cylinder cover 3 and is locked by the electromagnet 6; at this time, the tissue embedding boxes in the specimen basket 20 remain in a vertical state, and the liquid reagent and the molten paraffin can freely flow into and out of the tissue embedding boxes; when the embedding wax cylinder cover 3 is closed, the specimen basket rack fixing seat 14 and the specimen basket rack 12 together with the specimen basket 20 therein are rotated by 90 degrees along with the embedding wax cylinder cover 3, and the tissue embedding boxes in the specimen basket 20 also become horizontal, so that the molten paraffin fills the tissue embedding boxes.
[0041] When the specimen basket rack fixing seat 14 passes through the cylinder cover lock catch hole 22 of the embedding wax cylinder cover 3 through the specimen basket rack fixing seat lock catch 17 and is unlocked by the electromagnet 6, the embedding wax cylinder cover 3 is automatically opened, and the specimen basket rack fixing seat 14 and the specimen basket rack 12 together with the specimen basket 20 therein are separated from the embedding wax cylinder cover 3; at this time, the specimen basket rack 12 and the specimen basket 20 therein are placed on the specimen basket rack fixing seat 14 in a horizontal state, and the tissue embedding boxes in the specimen basket 20 remain in a horizontal state; the mechanical arm of the tissue dehydrator moves the specimen basket rack 12 and the specimen basket 20 therein out of the embedding wax cylinder 2 through the specimen basket rack double handle 13, and the excess liquid paraffin is drained above the embedding wax cylinder 2; after the liquid paraffin filled in the tissue embedding boxes cools down, the tissue is embedded in the tissue embedding boxes, and the mechanical arm of the tissue dehydrator places the specimen basket rack 12 in the storage position.
[0042] In this embodiment, the device can also be equipped with various sensors to ensure the accuracy and safety of operation. For example, a weight sensor can be provided on the specimen basket, and when an abnormal specimen weight is detected, the system will automatically stop running and issue an alarm. In addition, liquid level sensors and temperature sensors can be provided in the reagent cylinder, wax immersion cylinder and embedding wax cylinder to ensure that the liquid level of the reagent or wax is always maintained at the appropriate height and temperature, thereby preventing improper sample processing.
[0043] The basic principles, main features and advantages of the present application are demonstrated and described above. Those skilled in the art should understand that the present application is not limited to the above-mentioned embodiments, and the embodiments and the specification are only used to explain the structure and principle of the present application. Without departing from the spirit and scope of the present application, various modifications and improvements of the present application can be made, and these modifications and improvements all belong to the protection scope of the present application. The protection scope of the present application is defined by the appended claims and their equivalent scope.
Claims
1. An automatic embedding device of a tissue dehydrating machine, characterized by, The device comprises: a wax dipping cylinder assembly, an embedding wax cylinder assembly, a transmission mechanism assembly and a fixed support structure; The wax dipping cylinder assembly includes a wax dipping cylinder body, a cylinder cover, a heating plate located at the bottom of the cylinder, and a cylinder valve; The embedding wax cylinder assembly includes an embedding wax cylinder body, a heating plate at the bottom of the cylinder, a heating plate terminal, a cylinder valve, an embedding wax cylinder cover, a cylinder cover rotating shaft, a cylinder cover rotating shaft buckle, a cylinder cover rotating shaft gear, a specimen basket and a specimen basket fixing seat; wherein the embedding wax cylinder cover is provided with an electromagnet and a cylinder cover locking hole; the embedding wax cylinder cover is connected to the upper edge of one side of the embedding wax cylinder body through the cylinder cover rotating shaft buckle and the cylinder cover rotating shaft, and can rotate 90 degrees around the cylinder cover rotating shaft; The embedding wax cylinder cover and the specimen basket holder are connected to the cylinder cover rotating shaft, and both can move freely. The specimen basket holder passes through the cylinder cover locking hole of the embedding wax cylinder cover through the specimen basket holder locking buckle and is locked by an electromagnet. The specimen basket is provided with double handles, which can be movably placed on the specimen basket fixing seat, and the specimen basket can be movably placed on the specimen basket, and the specimen basket is provided with handles; The transmission mechanism assembly includes a motor and a motor gear. The motor is engaged with the cylinder cover shaft gear through the motor gear to drive the cylinder cover shaft to rotate the wax cylinder cover 90 degrees for opening and closing operations. The fixed support structure includes a heating plate, a cylinder fixing part and a motor fixing part.
2. The automatic embedding device of the tissue dehydrator according to claim 1, wherein: Tissue embedding cassettes are neatly layered or vertically arranged in rows in the specimen basket. The specimen basket is moved among the reagent cylinders, the wax immersion cylinder and the embedding wax cylinder of the tissue dehydrator by means of a specimen basket handle and a mechanical arm of the tissue dehydrator.