Microporous plate of magnetic bead kit

Abstract

The utility model discloses a microwell plate of a magnetic bead kit, and relates to the field of microwell plates, the microwell plate comprises a plate body and a plurality of mounting mechanisms mounted on the plate body, the outer wall of the top of the plate body is provided with a plurality of circular openings distributed at equal intervals, the mounting mechanisms are mounted in the circular openings, and each mounting mechanism comprises a mounting sleeve fixedly connected in the corresponding circular opening; the section of the mounting sleeve is of a T-shaped structure, two symmetrically-arranged locking assemblies are mounted on the outer wall of the mounting sleeve, and two symmetrically-arranged clamping assemblies are mounted on the outer wall of the bottom of the mounting sleeve. According to the microplate, the mounting mechanism is arranged on the microplate body, and the mounting sleeve and the locking assembly in the mounting mechanism are matched, so that test tubes of different specifications can be conveniently fixed in the mounting sleeve, and the problem that only test tubes of a single specification can be mounted on an existing microplate is solved.

Description

Technical Field

[0001] This application relates to the field of microplates, and more particularly to microplates for magnetic bead reagent kits. Background Art

[0002] The magnetic bead method utilizes the specific adsorption and desorption properties of superparamagnetic silica nanobeads on nucleic acids in two different solution environments. Combined with a magnetic separation device, a targeted reagent system and selective purification process for nucleic acid fragments are designed to achieve rapid purification of nucleic acid samples and screening of fragments.

[0003] Existing microplates can only fix one type or one size of test tube in practical use, which limits the scope of application of microplates. Utility Model Content

[0004] To address the issue of limited test tube specifications in existing microplate installations, this application provides a microplate for a magnetic bead reagent kit.

[0005] The microplate for the magnetic bead reagent kit provided in this application adopts the following technical solution:

[0006] The microplate of the magnetic bead reagent kit includes a plate body and multiple mounting mechanisms mounted on the plate body. The top outer wall of the plate body has multiple equally spaced circular openings. The mounting mechanisms are installed in the circular openings. Each mounting mechanism includes a mounting sleeve fixedly connected in the circular opening. The mounting sleeve has a T-shaped cross-section. The outer wall of the mounting sleeve is equipped with two symmetrically arranged locking components, and the bottom outer wall of the mounting sleeve is equipped with two symmetrically arranged clamping components.

[0007] By adopting the above technical solution, the mounting mechanism on the plate body facilitates the installation and fixing of test tubes of different specifications. The mounting sleeve in the mounting mechanism facilitates the passage of test tubes, thereby facilitating the protection of the test tubes. The locking component facilitates the locking and fixing of the test tubes, and the clamping component facilitates the auxiliary clamping of the test tubes.

[0008] The inner wall of the mounting sleeve is provided with two arc-shaped seats, and the two arc-shaped seats are driven by two locking components respectively.

[0009] By adopting the above technical solution, the locking component drives two arc-shaped seats to press against the test tube, thereby facilitating the fixation of test tubes of different specifications.

[0010] The locking assembly includes a locking box fixedly connected to the outer wall of the mounting sleeve, and a sliding seat is slidably connected to the inner wall of the locking box, with one end of the sliding seat fixedly connected to the arc-shaped seat.

[0011] By adopting the above technical solution, the movement of the sliding seat installed in the locking box directly drives the movement of the arc-shaped seat. The arc-shaped seat is equipped with a rubber pad, which facilitates the protection of the test tube.

[0012] The locking box has a rotatable double-ended screw connected to the inner walls on both sides, and the outer wall of the double-ended screw is screwed with two symmetrically arranged threaded sleeves.

[0013] By adopting the above technical solution, the two threaded sleeves can be directly driven to move towards or away from each other by rotating the bidirectional screw in the locking box.

[0014] The outer walls of both threaded sleeves are rotatably connected to support plates, and one end of each support plate is rotatably connected to a sliding seat. A groove is provided on one side of the outer wall of the locking box, and a rotating part is rotatably connected to the inner wall of the groove. One end of the drive shaft of the rotating part is fixedly connected to a bidirectional screw.

[0015] By adopting the above technical solution, the rotating part can be used to directly drive the bidirectional screw to rotate. When the bidirectional screw rotates, it drives the threaded sleeve to move. When the threaded sleeve moves, it cooperates with the support plate to easily drive the sliding seat to move.

[0016] The clamping assembly includes a clamping box fixedly connected to the mounting sleeve, and mounting rods are fixedly connected to the inner walls of both sides of the clamping box, with springs sleeved on the outer walls of both mounting rods.

[0017] By adopting the above technical solution, the clamping box facilitates the installation of the mounting rod, and the mounting rod facilitates the installation of the spring.

[0018] The outer walls of the two mounting rods are slidably connected to the same drive seat, and one end of the drive seat is fixedly connected to a clamping seat.

[0019] By adopting the above technical solution, the spring pushes the drive seat to drive the clamping seat to press against the test tube.

[0020] In summary, this application includes at least one of the following beneficial technical effects:

[0021] 1. This application provides an installation mechanism on the microplate body. The cooperation between the installation sleeve and the locking component in the installation mechanism facilitates the fixing of test tubes of different specifications in the installation sleeve, thus solving the problem that existing microplates can only install test tubes of a single specification.

[0022] 2. This application facilitates the direct drive of the arc-shaped seat to press against the test tube by setting a two-way screw, threaded sleeve, support plate and sliding seat in the locking assembly, thereby facilitating the locking and fixing of the test tube. In the clamping assembly, the clamping seat is pressed against the test tube under the drive of the spring, which in turn facilitates the fixing of the test tube. Attached Figure Description

[0023] Figure 1 This is a schematic diagram of the overall structure of the microplate of the magnetic bead reagent kit in the embodiments of this application;

[0024] Figure 2 This is a schematic diagram illustrating the main structure of the installation mechanism in the embodiments of this application;

[0025] Figure 3 This is a schematic diagram illustrating the three-dimensional structure of the installation mechanism, which is the main feature of this application.

[0026] Figure 4 This is a schematic diagram illustrating the main structure of the locking assembly in the embodiments of this application;

[0027] Figure 5 This is a schematic diagram illustrating the clamping assembly structure, which is a key feature of this application.

[0028] Reference numerals: 1. Plate body; 2. Mounting mechanism; 3. Mounting sleeve; 4. Arc-shaped seat; 5. Locking assembly; 6. Clamping assembly; 7. Locking box; 8. Sliding seat; 9. Bidirectional screw; 10. Threaded sleeve; 11. Support plate; 12. Rotating part; 13. Clamping box; 14. Mounting rod; 15. Spring; 16. Drive seat; 17. Clamping seat. DETAILED DESCRIPTION

[0029] The following is in conjunction with the appendix Figures 1-5 This application will be described in further detail.

[0030] This application discloses a microplate for a magnetic bead reagent kit.

[0031] Reference Figure 1-3 The microplate of the magnetic bead kit utilizes the properties of superparamagnetic silica nanobeads to specifically adsorb and desorb nucleic acids in two different solution environments. Combined with a magnetic separation device, it includes a plate body 1 and multiple mounting mechanisms 2 installed on the plate body 1. The top outer wall of the plate body 1 has multiple equally spaced circular openings, and the mounting mechanisms 2 are installed in the circular openings. The mounting mechanism 2 is designed to facilitate the installation and fixation of test tubes.

[0032] Reference Figure 2-3The installation mechanism 2 includes an installation sleeve 3 fixedly connected in a circular opening. The installation sleeve 3 has a T-shaped cross-section, which facilitates the protection of the test tube. Two symmetrically arranged locking components 5 are installed on the outer wall of the installation sleeve 3, which facilitates the locking and fixing of the test tube. Two symmetrically arranged clamping components 6 are installed on the bottom outer wall of the installation sleeve 3. Two arc-shaped seats 4 are provided on the inner wall of the installation sleeve 3. Rubber pads are provided on the arc-shaped seats 4 to facilitate the protection of the test tube and prevent damage to the surface of the test tube. The two arc-shaped seats 4 are driven by the two locking components 5 respectively. The installation mechanism 2 on the plate body 1 facilitates the installation and fixing of test tubes of different specifications. The installation sleeve 3 in the installation mechanism 2 facilitates the passage of the test tube, thus facilitating the protection of the test tube. The locking components 5 facilitate the locking and fixing of the test tube. The clamping components 6 facilitate the clamping of the test tube. The locking components 5 drive the two arc-shaped seats 4 to press against the test tube, thus facilitating the fixing of test tubes of different specifications.

[0033] Reference Figure 2-3 The locking assembly 5 for fixing the test tube includes a locking box 7 fixedly connected to the outer wall of the mounting sleeve 3, and a sliding seat 8 slidably connected to the inner wall of the locking box 7. One end of the sliding seat 8 is fixedly connected to the arc-shaped seat 4. The same double-acting screw 9 is rotatably connected to the inner walls of both sides of the locking box 7, and two symmetrically arranged threaded sleeves 10 are screwed to the outer wall of the double-acting screw 9. Support plates 11 are rotatably connected to the outer walls of both threaded sleeves 10, and one end of each support plate 11 is rotatably connected to the sliding seat 8. A groove is provided on one side of the outer wall of the locking box 7, and the groove... The inner wall is rotatably connected to a rotating part 12. One end of the drive shaft of the rotating part 12 is fixedly connected to the double-acting screw 9. When the two double-acting screws 9 rotate, they directly drive the two threaded sleeves 10 to move towards or away from each other. When the two threaded sleeves 10 move towards each other, they directly cooperate with the support plate 11 to drive the sliding seat 8 away from the double-acting screw 9. When the two threaded sleeves 10 move away from each other, they directly drive the sliding seat 8 to move closer to the double-acting screw 9, thus facilitating the clamping of the test tube with the arc-shaped seat 4. The adjustable arc-shaped seat 4 is convenient for clamping and fixing test tubes of different specifications.

[0034] In use, the rotating part 12 can directly drive the bidirectional screw 9 to rotate. When the bidirectional screw 9 rotates, it drives the threaded sleeve 10 to move. When the threaded sleeve 10 moves, it cooperates with the support plate 11 to drive the sliding seat 8 to move. The movement of the sliding seat 8 directly drives the arc-shaped seat 4 to move. The arc-shaped seat 4 is equipped with a rubber pad, which facilitates the protection of the test tube.

[0035] Reference Figure 5The clamping assembly 6 for assisting in fixing the test tube includes a clamping box 13 fixedly connected to the mounting sleeve 3. Mounting rods 14 are fixedly connected to the inner walls of both sides of the clamping box 13. Springs 15 are sleeved on the outer walls of both mounting rods 14. A common drive seat 16 is slidably connected to the outer walls of the two mounting rods 14, and a clamping seat 17 is fixedly connected to one end of the drive seat 16.

[0036] In use, the clamping box 13 facilitates the installation of the mounting rod 14, and the mounting rod 14 facilitates the installation of the spring 15. The spring 15 pushes the drive seat 16 to drive the clamping seat 17 to press against the test tube.

[0037] The implementation principle of the microplate of the magnetic bead reagent kit in this application embodiment is as follows: When using the test tube, first insert the test tube into the installation sleeve 3, and then rotate the rotating part 12 on the locking assembly 5. When the rotating part 12 rotates, it directly drives the bidirectional screw 9 to rotate. When the bidirectional screw 9 rotates, it directly drives the two threaded sleeves 10 to move towards or away from each other. When the two threaded sleeves 10 move towards each other, they cooperate with the two support plates 11 to directly push the sliding seat 8 to drive the arc-shaped seat 4 to press against the outer wall of the test tube. The two springs 15 in the two clamping assemblies 6 directly push the drive seat 16 to drive the clamping seat 17 to press against the outer wall of the test tube, thereby ensuring the stable installation of the test tube.

[0038] The above are all preferred embodiments of the present application, and are not intended to limit the scope of protection of the present application. Therefore, any equivalent changes made based on the structure, shape, and principle of the present application should be included in the scope of protection of the present application.

Claims

1. A microplate for a magnetic bead reagent kit, comprising a plate body (1) and a plurality of mounting mechanisms (2) mounted on the plate body (1), characterized in that: The top outer wall of the plate body (1) has multiple equally spaced circular openings. The mounting mechanism (2) is installed in the circular openings. The mounting mechanism (2) includes a mounting sleeve (3) fixedly connected in the circular openings. The mounting sleeve (3) has a T-shaped cross-section. The outer wall of the mounting sleeve (3) is equipped with two symmetrically arranged locking components (5). The bottom outer wall of the mounting sleeve (3) is equipped with two symmetrically arranged clamping components (6).

2. The microplate of the magnetic bead reagent kit according to claim 1, characterized in that: The inner wall of the mounting sleeve (3) is provided with two arc-shaped seats (4), and the two arc-shaped seats (4) are driven by two locking components (5) respectively.

3. The microplate of the magnetic bead reagent kit according to claim 2, characterized in that: The locking assembly (5) includes a locking box (7) fixedly connected to the outer wall of the mounting sleeve (3), and a sliding seat (8) is slidably connected to the inner wall of the locking box (7), one end of the sliding seat (8) being fixedly connected to the arc-shaped seat (4).

4. The microplate of the magnetic bead reagent kit according to claim 3, characterized in that: The locking box (7) has the same bidirectional screw (9) rotatably connected to the inner walls on both sides, and the outer wall of the bidirectional screw (9) is screwed with two symmetrically arranged threaded sleeves (10).

5. The microplate of the magnetic bead reagent kit according to claim 4, characterized in that: The outer walls of the two threaded sleeves (10) are rotatably connected to support plates (11), and one end of each support plate (11) is rotatably connected to a sliding seat (8). A groove is provided on one side of the outer wall of the locking box (7), and a rotating part (12) is rotatably connected to the inner wall of the groove. One end of the drive shaft of the rotating part (12) is fixedly connected to a bidirectional screw (9).

6. The microplate of the magnetic bead reagent kit according to claim 5, characterized in that: The clamping assembly (6) includes a clamping box (13) fixedly connected to the mounting sleeve (3), and mounting rods (14) are fixedly connected to the inner walls on both sides of the clamping box (13), and springs (15) are sleeved on the outer walls of the two mounting rods (14).

7. The microplate of the magnetic bead reagent kit according to claim 6, characterized in that: The outer walls of the two mounting rods (14) are slidably connected to the same drive seat (16), and one end of the drive seat (16) is fixedly connected to a clamping seat (17).

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