Feeding push valve capable of sterilizing on line and used for bioreactor

By designing a feeding push valve that can be sterilized online and using a combination of a feeding tube and a rotary switch, the sterilization safety problem of the needle-type feeding valve is solved, and safe online sterilization and continuous feeding of the bioreactor are achieved.

CN223483472UActive Publication Date: 2025-10-28SHANGHAI NAILI FLUID EQUIP
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Patent Information

Application Number
CN202422753568.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-11-12
Publication Date
2025-10-28
Estimated Expiration
2034-11-12

AI Technical Summary

Technical Problem

The sterilization of the needle-type feeding valve of the existing bioreactor has safety issues. The interface needs to be wiped with open flame, which is inconvenient and unsafe to operate.

Method used

A feeding push valve that can be sterilized online is designed. Through the combination of a feeding pipe, a connector, a sleeve and a rotary switch, the feeding pipe can be rotated counterclockwise to close the feeding port and rotated clockwise to enter the tank for feeding, avoiding the use of open flame sterilization.

Benefits of technology

The online sterilization of the bioreactor is realized, the safety is improved, the operation is simple, and continuous feeding can be achieved.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of bioreactor feeding, and discloses an online sterilization feeding push valve for a bioreactor, which comprises a feed delivery pipe and a connector mounted on a bioreactor tank body, a sleeve is mounted on the surface of the feed delivery pipe, the connector is mounted on the surface of the sleeve, and the feed delivery pipe and the connector are connected through a pipeline. And the surface of the sleeve is in threaded connection with a rotary switch, and a first clamping groove is formed in the surface of the material conveying pipe. According to the on-line sterilization material supplementing push valve for the bioreactor, through the arrangement of the material conveying pipe, the connector, the sleeve and the rotary switch, when the material conveying pipe anticlockwise rotates and retracts to the position flush with the sleeve, a material supplementing opening is completely closed, the material conveying pipe is isolated from the tank body, and on-line sterilization of the tank body and the material supplementing push valve can be achieved in the state; the material supplementing push valve rotates clockwise, the head end of the material conveying pipe enters the tank body, the material supplementing opening is exposed in the tank body, at the moment, the material supplementing pump is started, the materials enter the tank body through the material conveying pipe, and continuous material supplementing can be achieved.
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Description

Technical Field

[0001] This utility model relates to the field of bioreactor feeding technology, specifically to an online sterilizable feeding push valve for bioreactors. Background Art

[0002] A bioreactor is a device system that utilizes the biological functions of enzymes or organisms (such as microorganisms) to carry out biochemical reactions in vitro. It is a kind of biological function simulator, such as fermenters, immobilized enzymes, or immobilized cell reactors. It has important applications in winemaking, pharmaceutical production, concentrated jam production, fruit juice fermentation, and the degradation of organic pollutants.

[0003] The commonly used feed valve in bioreactors is the pin-type feed valve. The disadvantage of this type of feed valve is that sterilization is dangerous, as it requires wiping the interface with alcohol and then igniting it. This operation method is not safe and is inconvenient. Utility Model Content

[0004] To address the shortcomings of existing technologies, this invention provides an online sterilizable feed push valve for bioreactors, solving the problems mentioned in the background.

[0005] This utility model provides the following technical solution: an online sterilizable feeding push valve for a bioreactor, comprising: a feed pipe and a connector installed on the bioreactor tank, wherein a sleeve is installed on the surface of the feed pipe, the connector is installed on the surface of the sleeve, and a rotary switch is threadedly connected to the surface of the sleeve, a first groove is formed on the surface of the feed pipe, and a first retaining spring is installed on the inner wall of the first groove, and the first retaining spring is connected to the surface of the rotary switch;

[0006] The inside of the conveying pipe is provided with a hollow flow channel, and the surface of the conveying pipe is provided with a feeding port, which is connected to the hollow flow channel.

[0007] Preferably, the surface of the sleeve is provided with a first limiting part, and the surface of the first limiting part is connected to the inner wall of the connector.

[0008] Preferably, the surface of the sleeve is provided with a second groove, and the inner wall of the inner wall of the second groove is engaged with a second retaining spring, the surface of the second retaining spring being connected to the surface of the connector.

[0009] Preferably, the surface of the feed pipe is provided with a first mounting groove and a second mounting groove, which are respectively located on both sides of the feed port. A first sealing ring is installed on the inner wall of the first mounting groove, and a second sealing ring is installed on the inner wall of the second mounting groove. The surfaces of the first sealing ring and the second sealing ring are movably connected to the inner wall of the sleeve.

[0010] Preferably, one end of the conveying pipe is provided with a second limiting part, and the other end of the conveying pipe is provided with a connecting part.

[0011] Preferably, the surface of the sleeve is provided with a third mounting groove, and a second sealing ring is installed on the inner wall of the second mounting groove.

[0012] Preferably, the surfaces of the connector and the rotary switch are knurled with knurled grooves.

[0013] Compared with the prior art, the present invention has the following beneficial effects:

[0014] This online sterilizable feed valve for bioreactors, consisting of a feed pipe, connector, sleeve, and rotary switch, allows for online sterilization of both the tank and the feed valve. When the feed pipe retracts counter-clockwise to a position flush with the sleeve, the feed port is completely closed, isolating the feed pipe from the tank. This eliminates the need for open flame sterilization. Rotating the feed valve clockwise allows the feed pipe head to enter the tank, exposing the feed port. Activating the feed pump at this point allows material to enter the tank through the feed pipe, enabling continuous feeding. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the structure of this utility model;

[0016] Figure 2 This is a side sectional view of the feed inlet of this utility model in the closed state;

[0017] Figure 3 This is a side sectional view of the feed inlet of this utility model in the open state;

[0018] Figure 4 This is a side sectional view of the material conveying pipe of this utility model;

[0019] Figure 5 This is a schematic diagram of the side section structure of the sleeve of this utility model.

[0020] In the diagram: 1. Feed pipe; 2. Connector; 3. Sleeve; 4. Rotary switch; 5. First slot; 6. First snap ring; 7. Hollow flow channel; 8. Feed port; 9. First limiting part; 10. Second slot; 11. Second snap ring; 12. First mounting groove; 13. Second mounting groove; 14. First sealing ring; 15. Second sealing ring; 16. Second limiting part; 17. Connecting part; 18. Third mounting groove; 19. Third sealing ring. Detailed Implementation

[0021] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0022] Please see Figure 1-5 An online sterilizable feed push valve for a bioreactor includes: a feed pipe 1 and a connector 2 installed on the bioreactor tank. A sleeve 3 is installed on the surface of the feed pipe 1, the connector 2 is installed on the surface of the sleeve 3, and a rotary switch 4 is threadedly connected to the surface of the sleeve 3. A first groove 5 is formed on the surface of the feed pipe 1, and a first retaining spring 6 is installed on the inner wall of the first groove 5 and connected to the surface of the rotary switch 4. A hollow flow channel 7 is provided inside the feed pipe 1, and a feed port 8 is provided on the surface of the feed pipe 1 and is connected to the hollow flow channel 7. The surfaces of the connector 2 and the rotary switch 4 are knurled with knurled grooves.

[0023] The sleeve 3 has a first limiting part 9 on its surface. The surface of the first limiting part 9 is connected to the inner wall of the connector 2. The first limiting part 9 is in contact with the inside of the connector 2, so that the sleeve 3 will not slip out of the connector 2. The sleeve 3 has a second slot 10 on its surface. The inner wall of the second slot 10 is engaged with a second snap spring 11. The surface of the second snap spring 11 is connected to the surface of the connector 2.

[0024] The surface of the conveying pipe 1 is provided with a first mounting groove 12 and a second mounting groove 13. The first mounting groove 12 and the second mounting groove 13 are respectively located on both sides of the feeding port 8. A first sealing ring 14 is installed on the inner wall of the first mounting groove 12, and a second sealing ring 15 is installed on the inner wall of the second mounting groove 13. The surfaces of the first sealing ring 14 and the second sealing ring 15 are movably connected to the inner wall of the sleeve 3. A second limiting part 16 is provided at one end of the conveying pipe 1, and a docking part 17 is provided at the other end of the conveying pipe 1. The docking part is connected to the feed hose.

[0025] The surface of the sleeve 3 is provided with a third mounting groove 18, and the inner wall of the second mounting groove 13 is provided with a third sealing ring 19.

[0026] The feed pipe 1 has a hollow flow channel 7 inside. The docking part 17 connects to the external feed hose. One end with the second limiting part 16 is inserted into the bioreactor tank. The feed pipe 1 is fitted into the sleeve 3 and fixed with the first retaining spring 6. The feed pipe 1 is provided with a first sealing ring 14 and a second sealing ring 15. The connector 2 is fitted onto the surface of the first limiting part 9 of the sleeve 3 and is secured with the first retaining spring 6. One end of the sleeve 3 with an external thread is connected to the inner thread of the rotary switch 4 and secured with the second retaining spring 11. The sleeve 3 is provided with a third sealing ring 19. The inner thread of the connector 2 is installed on the outer side wall of the bioreactor tank. When the rotary switch 4 is rotated clockwise to its limit, the feed port 8 of the feed pipe 1 is exposed in the sleeve 3 for feeding. When the rotary switch 4 is rotated counterclockwise to its limit, the feed port 8 of the feed pipe 1 retracts into the sleeve 3, the feed port 8 is completely closed, and feeding stops. In this state, the tank and the feed push valve can be sterilized online without the need for open flame sterilization. When the feed push valve is rotated clockwise, the head end of the feed pipe 1 enters the tank, and the feed port 8 is exposed in the bioreactor tank. At this time, the feed pump is started, and the material enters the tank through the feed pipe 1, which can realize continuous feeding.

[0027] Although the embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and variations may be made to these embodiments without departing from the principles and spirit of the present invention, and the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An online sterilizable feed push valve for a bioreactor, characterized in that, include: The feed pipe (1) and the connector (2) installed on the bioreactor tank are provided. The surface of the feed pipe (1) is fitted with a sleeve (3). The connector (2) is installed on the surface of the sleeve (3). A rotary switch (4) is threaded onto the surface of the sleeve (3). A first slot (5) is provided on the surface of the feed pipe (1). A first snap ring (6) is installed on the inner wall of the first slot (5). The first snap ring (6) is connected to the surface of the rotary switch (4). The inside of the conveying pipe (1) is provided with a hollow flow channel (7), and the surface of the conveying pipe (1) is provided with a feeding port (8), and the feeding port (8) is connected to the hollow flow channel (7); The surface of the feed pipe (1) is provided with a first mounting groove (12) and a second mounting groove (13). The first mounting groove (12) and the second mounting groove (13) are respectively located on both sides of the feed inlet (8). The inner wall of the first mounting groove (12) is provided with a first sealing ring (14), and the inner wall of the second mounting groove (13) is provided with a second sealing ring (15). The surfaces of the first sealing ring (14) and the second sealing ring (15) are movably connected to the inner wall of the sleeve (3).

2. The online sterilizable feed push valve for a bioreactor according to claim 1, characterized in that, The sleeve (3) has a first limiting part (9) on its surface, and the surface of the first limiting part (9) is connected to the inner wall of the connector (2).

3. The online sterilizable feed push valve for a bioreactor according to claim 2, characterized in that, The sleeve (3) has a second slot (10) on its surface. The inner wall of the second slot (10) is fitted with a second snap ring (11). The surface of the second snap ring (11) is connected to the surface of the connector (2).

4. The online sterilizable feed push valve for a bioreactor according to claim 1, characterized in that, One end of the conveying pipe (1) is provided with a second limiting part (16), and the other end of the conveying pipe (1) is provided with a docking part (17).

5. The online sterilizable feed push valve for a bioreactor according to claim 1, characterized in that, The sleeve (3) has a third mounting groove (18) on its surface, and a third sealing ring (19) is installed on the inner wall of the second mounting groove (13).

6. The online sterilizable feed push valve for a bioreactor according to claim 1, characterized in that, The surfaces of the connector (2) and the rotary switch (4) are knurled with knurled grooves.