Stacked mouse embryo culture device
By designing a stacked mouse embryo culture device and employing structures such as limiting plates and dampers, the problem of tilting and tipping over in traditional culture methods was solved, improving the stability of the experiment and the cleanliness of the environment, and ensuring the reliability of the experimental results.
Patent Information
- Application Number
- CN202423004975.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-06
- Publication Date
- 2025-10-31
- Estimated Expiration
- 2034-12-06
AI Technical Summary
Traditional planar mouse embryo culture methods require a large area, are inconvenient to manage, and make it difficult to achieve precise control of environmental conditions. Furthermore, the lack of a fixed structure in stacked devices can cause culture dishes to tilt or tip over, affecting the experimental process and the reliability of the results.
A stacked mouse embryo culture device was designed, comprising multiple placement layers, a miniature air conditioner, a placement plate, a partition plate, a spring telescopic rod, and a limiting plate. The limiting plate clamps the culture dish, and combined with a two-way cylinder and a damper, the stability and safety of the culture dish are ensured. The environment is improved by using a heightening rack and a filter.
This approach ensures the stability and safety of the petri dishes, reduces the risk of spilling the culture medium, improves the safety of experimental operations and the cleanliness of the environment, and guarantees the reliability of experimental results.
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Figure CN223488951U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of laboratory animal equipment technology, and in particular to a stacked mouse embryo culture device. Background Technology
[0002] With the development of biomedical research, mice, as model organisms, play an extremely important role in many fields such as genetics, developmental biology, and disease model construction. In order to ensure normal embryonic development and obtain accurate experimental results, researchers need to place the embryos in specific culture media, which are rich in necessary nutrients, growth factors and other substances that are crucial to embryonic development.
[0003] Traditional planar culture methods are space-consuming, inconvenient to manage, and difficult to precisely control environmental conditions. When using traditional stacked devices, the lack of a dedicated design for the placement plates or trays to secure the containers containing embryos poses a challenge to experimental operations. Specifically, when these placement plates are removed or moved from the equipment, the containers are prone to tilting or even tipping over, causing the precious culture medium to spill unexpectedly, affecting the experimental process and the reliability of the results. Therefore, we propose a stacked mouse embryo culture device to solve the above problems. Summary of the Invention
[0004] In order to overcome the shortcomings of the prior art, this utility model provides a stacked mouse embryo culture device.
[0005] The technical solution of this utility model is as follows: a stacked mouse embryo culture device, comprising a culture box and a miniature air conditioner. The culture box serves as the carrier of this culture device, and the culture box has multiple placement layers inside. The miniature air conditioner is located on the rear side wall of the culture box and is used to regulate the appropriate culture temperature inside the culture box. It also includes: multiple placement plates, each disposed in each placement layer of the culture box; a handle, installed on the front side plate of each placement plate; and partition plates, fixed to each placement plate, the partition plates intersecting in a cross shape to separate the placement plates. The plate is divided into multiple culture compartments; culture dishes are placed in each compartment of the plate, and the culture dishes are containers for mouse embryo culture; multiple sets of spring telescopic rods are provided and are respectively set in each compartment of the plate, each set of spring telescopic rods has two rods and is symmetrically fixed to the inner wall of each compartment of the culture box, and the spring telescopic rods are composed of telescopic sleeves and built-in springs; multiple sets of limiting plates are provided and are respectively set on each set of spring telescopic rods, and the limiting plates are used to clamp and limit the culture dishes placed on the plate, thereby improving the stability of mouse embryo culture and reducing the risk of tilting or tipping of the culture solution.
[0006] In one embodiment, the limiting plate is a "C"-shaped clamp. The limiting plates in the same group face each other and clamp the culture dish under the action of the spring telescopic rod. Each clamping surface of the limiting plate is provided with a rubber block. The rubber block is tightly attached to the clamping surface of the limiting plate. The limiting plate elastically limits and clamps the culture dish through the rubber block, thereby improving the limiting stability of the culture dish.
[0007] In one embodiment, two symmetrically distributed bidirectional cylinders are fixedly installed in the middle of the placement plate. A connecting plate is installed on the telescopic rod of each bidirectional cylinder. A contact plate is fixed on the side wall of each set of limiting plates that are close to each other. The connecting plate and the contact plate on the same side are in contact. The connecting plate on the bidirectional cylinder pushes the limiting plate open through the contact plate, thereby facilitating the loading and unloading of the culture dish that is limited between the limiting plates.
[0008] In one embodiment, multiple sets of mounting plates are symmetrically fixed on the inner walls of both sides of the breeding box. The number of mounting plates is the same as the number of placement plates. A damper is provided between the mounting plate and the corresponding placement plate. The damper is used to slow down the pushing and pulling speed of the placement plate in the breeding box, thereby improving the stability and safety when the placement plate is picked up and put down, and reducing the risk of the culture dish on the placement plate tipping over.
[0009] In one embodiment, the system also includes a lifter frame, which is provided at the bottom of the breeding box. The lifter frame is used to support and raise the entire breeding box, thereby improving the living environment of the mice in the breeding box and improving the management and maintenance efficiency of the breeding device.
[0010] In one embodiment, openings are provided on all four side walls of the riser, and filters are provided at each opening. The filters are used to capture dust, hair and other fine particles in the surrounding environment while maintaining good ventilation of the breeding device.
[0011] The beneficial effects of this utility model are as follows: 1. This utility model divides the placement plate into multiple independent compartments by using a partition plate, and with the help of a spring telescopic rod and a limiting plate, it ensures that the culture dish will not easily tilt or tip over during transportation or operation, thereby protecting the mouse embryos in the breeding box.
[0012] 2. This utility model, through the design of a two-way cylinder and connecting plate, allows for quick and safe loading and unloading of culture dishes. At the same time, the application of a damper can reduce the speed when the placement plate is pushed and pulled, increasing the stability and safety during operation.
[0013] 3. The height-increasing frame of this utility model can not only increase the height of the entire device, making daily management and maintenance easier, but also maintain good ventilation conditions with the filter screen, reducing the impact of dust and other pollutants on the internal environment, which is conducive to creating a cleaner and healthier growth environment for mouse embryos. Attached Figure Description
[0014] Figure 1 This is a three-dimensional structural diagram of the present invention.
[0015] Figure 2 This is a cross-sectional view of the breeding box of this utility model.
[0016] Figure 3 This diagram shows the connection relationship between the placement plate, petri dish, spring telescopic rod, and rubber block of this utility model.
[0017] Figure 4 This is a schematic diagram showing the cooperation relationship between the limiting plate, the bidirectional cylinder, the connecting plate, and the contact plate of this utility model.
[0018] The markings in the diagram are as follows: 1-breeding box, 2-mini air conditioner, 3-placement plate, 4-handle, 5-culture dish, 6-spring telescopic rod, 61-limiting plate, 7-rubber block, 8-divider plate, 9-double-acting cylinder, 10-connecting plate, 11-contact plate, 12-mounting plate, 13-damper, 14-elevator, 141-filter screen. Detailed Implementation
[0019] Exemplary embodiments will now be described in detail, examples of which are illustrated in the accompanying drawings. When the following description refers to the drawings, unless otherwise indicated, the same numbers in different drawings denote the same or similar elements. The embodiments described in the following exemplary embodiments do not represent all embodiments consistent with this application. Rather, they are merely examples of apparatuses and methods consistent with some aspects of this application as detailed in the appended claims.
[0020] A stacked mouse embryo culture device, such as Figures 1-4As shown, the device includes a rearing box 1 and a miniature air conditioner 2. The rearing box 1 serves as the carrier of this rearing device, and its interior has multiple layers. The miniature air conditioner 2 is located on the rear wall of the rearing box 1 and is used to regulate the appropriate rearing temperature inside the rearing box 1. The device also includes: multiple placement plates 3, each located within one of the layers of the rearing box 1; handles 4, mounted on the front panel of the placement plates 3; partition plates 8, fixed to each placement plate 3, forming a cross shape to divide the placement plates 3 into multiple culture compartments; culture dishes 5, located in each compartment of the placement plates 3, serving as containers for mouse embryo rearing; and multiple sets of spring-loaded telescopic rods 6, each located in one of the compartments of the placement plates 3. Two spring telescopic rods 6 are symmetrically fixed to the inner wall of each compartment of the breeding box 1. The spring telescopic rod 6 consists of a telescopic sleeve and an internal spring. Multiple limiting plates 61 are provided and are respectively set on each set of spring telescopic rods 6. The limiting plates 61 are used to clamp and limit the culture dish 5 placed on the placement plate 3, thereby improving the stability of mouse embryo culture and reducing the risk of tilting or tipping of the culture liquid. The limiting plates 61 are "C"-shaped clamps. Under the action of the spring telescopic rods 6, the limiting plates 61 in the same group face each other and clamp the culture dish 5. Rubber blocks 7 are provided on the clamping surface of the limiting plates 61. The rubber blocks 7 are tightly attached to the clamping surface of the limiting plates 61. The limiting plates 61 elastically limit and clamp the culture dish 5 through the rubber blocks 7, improving the limiting stability of the culture dish 5.
[0021] like Figure 2 and Figure 4 As shown, two symmetrically distributed bidirectional cylinders 9 are fixedly installed in the middle of the placement plate 3. A connecting plate 10 is installed on the telescopic rod of each bidirectional cylinder 9. A contact plate 11 is fixed on the side wall of each set of limiting plates 61 that are close to each other. The connecting plate 10 and the contact plate 11 on the same side are in contact. The connecting plate 10 on the bidirectional cylinder 9 pushes and opens the limiting plate 61 through the contact plate 11, so as to facilitate the loading and unloading of the culture dish 5 that is limited between the limiting plates 61.
[0022] like Figure 3 As shown, multiple sets of mounting plates 12 are symmetrically fixed on the inner walls of both sides of the breeding box 1. The number of mounting plates 12 is the same as the number of placement plates 3. A damper 13 is provided between the mounting plate 12 and the corresponding placement plate 3. The damper 13 is used to slow down the pushing and pulling speed of the placement plate 3 in the breeding box 1, thereby improving the stability and safety of the placement plate 3 when it is picked up and put down, and reducing the risk of the culture dish 5 on the placement plate 3 tipping over.
[0023] like Figure 1As shown, it also includes a lift frame 14. The bottom of the breeding box 1 is equipped with a lift frame 14, which is used to support and raise the entire breeding box 1, thereby improving the living environment of the mice in the breeding box 1 and improving the management and maintenance efficiency of the breeding device. There are openings on the four side walls of the lift frame 14, and each opening of the lift frame 14 is equipped with a filter screen 141. The filter screen 141 is used to capture dust, hair and other fine particles in the surrounding environment, while maintaining good ventilation of the breeding device.
[0024] Firstly, the rearing box 1, as the core carrier of the entire device, has multiple placement layers inside. Each layer is equipped with a dedicated placement plate 3, and these placement plates 3 are fitted with partition plates 8, dividing each placement plate 3 into multiple independent culture compartments. Each compartment contains a culture dish 5 for mouse embryo culture, ensuring that mouse embryos of different batches or species can be effectively isolated and managed. A miniature air conditioner 2 is installed on the rear wall of the rearing box 1. It is responsible for monitoring and regulating the temperature inside the box to maintain an ideal temperature and humidity environment suitable for mouse embryo development. When it is necessary to replace or check the culture dish 5, the operator can easily open or close the limiting plate 61 by controlling the bidirectional cylinder 9. When the bidirectional cylinder 9 opens through the connecting plate 10, it pushes the contact plate 11, making... Contact plate 11 drives limit plate 61 to open against the elastic force inside spring telescopic rod 6, thus facilitating loading and unloading; conversely, when connecting plate 10 of spring telescopic rod 6 retracts and disengages from contact plate 11, the limit plate 61 closes and locks the culture dish 5 under the elastic force of spring telescopic rod 6, simplifying daily maintenance procedures and enhancing operational safety. Since the dampers 13 on both sides of the inner wall of the culture box 1 work in conjunction with the placement plate 3, they can slow down the movement during pushing and pulling, ensuring smooth operation and reducing the impact of accidental collisions. Finally, the riser 14 at the bottom not only improves the stability of the overall structure, but also optimizes air circulation through the filter screen 141 set around it, blocking dust and other impurities from entering, thus helping to create a cleaner and healthier cultivation environment.
[0025] It should be understood that this embodiment is for illustrative purposes only and is not intended to limit the scope of the present invention. Furthermore, it should be understood that after reading the teachings of this invention, those skilled in the art can make various alterations or modifications to the invention, and these equivalent forms also fall within the scope defined by the appended claims.
Claims
1. A stacked mouse embryo culture device, comprising a culture box (1) and a miniature air conditioner (2), wherein the culture box (1) has multiple layers inside, and the miniature air conditioner (2) is disposed on the rear side wall of the culture box (1); Its features are, Also includes: The placement board (3) is provided in multiple pieces and is respectively placed in each layer of the breeding box (1); The handle (4) is installed on the front side plate of the placement plate (3); A partition plate (8) is fixed on each of the placement plates (3). The partition plates (8) are intersected in a cross shape on the placement plates (3) and divide the placement plates (3) into multiple culture compartments. Petri dishes (5) are placed in each compartment of the placement plate (3); Multiple sets of spring telescopic rods (6) are provided and are respectively set in each compartment of the placement plate (3). Each set of spring telescopic rods (6) has two rods and is symmetrically fixed on the inner wall of each compartment of the breeding box (1). The limiting plate (61) is provided in multiple sets and is respectively set on each set of spring telescopic rods (6). The limiting plate (61) is used to clamp and limit the petri dish (5) placed on the placement plate (3).
2. The stacked mouse embryo culture device as described in claim 1, characterized in that, The limiting plate (61) is a "C" shaped clamp. The limiting plates (61) in the same group face each other and clamp the culture dish (5) under the action of the spring telescopic rod (6). Rubber blocks (7) are provided on the clamping surface of the limiting plate (61).
3. The stacked mouse embryo culture device as described in claim 2, characterized in that, Two symmetrically distributed bidirectional cylinders (9) are fixedly installed in the middle of the placement plate (3). A connecting plate (10) is installed on the telescopic rod of each bidirectional cylinder (9). A contact plate (11) is fixed on the side wall of each set of limiting plates (61) that are close to each other. The connecting plate (10) and the contact plate (11) on the same side are in contact.
4. The stacked mouse embryo culture device as described in claim 3, characterized in that, Multiple sets of mounting plates (12) are symmetrically fixed on the inner walls of both sides of the breeding box (1). The number of mounting plates (12) is the same as the number of placement plates (3). A damper (13) is provided between the mounting plate (12) and the corresponding placement plate (3). The damper (13) is used to slow down the speed at which the placement plate (3) is pushed and pulled in the breeding box (1).
5. The stacked mouse embryo culture device as described in claim 4, characterized in that, It also includes a riser frame (14), which is provided at the bottom of the breeding box (1) and is used to support and raise the entire breeding box (1).
6. The stacked mouse embryo culture device as described in claim 5, characterized in that, The four sides of the riser frame (14) have openings, and each opening of the riser frame (14) is equipped with a filter screen (141).