Gastric lavage device

Abstract

The utility model provides a gavage device which comprises an injection tube and a gavage needle which are connected through an installation head, a push rod is arranged in the injection tube, the gavage needle comprises a stainless steel gavage needle and a cover body which is sleeved on the outer edge of the stainless steel gavage needle, the cover body is of a trumpet-shaped structure with a round hole in the center, the round hole is sleeved on the outer edge of the stainless steel gavage needle, and the stainless steel gavage needle is sleeved on the round hole. A sponge ring is attached to the inner wall of the cover body. The traditional Chinese medicine compound liquid medicine lavage device is particularly suitable for lavage experiments of traditional Chinese medicine compound liquid medicine, facilitates repeated lavage of experimental animals such as mice and the like, can effectively prevent the liquid medicine from overflowing and blocking a tube during lavage, reduces discomfort of the experimental animals, reduces damage to esophagus of the experimental animals, and can ensure that the head and the neck of the mice are in a vertical state during lavage.

Description

Technical Field

[0001] This utility model relates to the field of experimental drug delivery equipment, specifically a gavage device. Background Technology

[0002] Animal experiments typically require the use of a gavage device to administer medication into the stomach of an animal (such as a mouse). Commonly used gavage devices include disposable gavage needles and stainless steel gavage needles.

[0003] The main drawbacks of disposable gavage syringes are threefold: First, the required quantity of consumables is too large, especially for experiments involving traditional Chinese medicine, where the administration cycle is typically 4-12 weeks, making disposable syringes prohibitively expensive. Second, disposable gavage syringes are usually made of PTFE (polytetrafluoroethylene), which is easily deformed by rodents through chewing. Repeated use to reduce costs can lead to bacterial infections in mice. Third, frequent insertion can damage the mucous membranes and mouth area of ​​mice. Fourth, there is a risk of leakage. Fifth, mice may bite or injure operators due to discomfort during gavage.

[0004] Existing stainless steel gavage needles present the following problems during gavage in mice: First, there is a risk of accidental injury or perforation of the mouse's esophagus. Second, because the mouse's trachea is close to its esophagus, if the mouse's head cannot be relatively upright during gavage, the gavage needle may accidentally enter the trachea, potentially causing the medication to enter and leading to immediate suffocation and death. Third, there is a risk of leakage. Utility Model Content

[0005] To address the problems of existing technologies, this invention provides a gavage device, particularly suitable for gavage experiments involving compound traditional Chinese medicine solutions. It facilitates repeated gavage procedures on experimental animals such as mice over extended periods; ensures adequate dosage and treatment duration; effectively prevents spillage during gavage; reduces esophageal damage to experimental animals during gavage; and maintains an upright head and neck position during mouse gavage, preventing accidental insertion of the gavage needle into the mouse's trachea and reducing the possibility of accidental bites or injuries to experimental personnel.

[0006] This utility model provides a gavage device, including an injection tube and a gavage needle connected by an installation head. A push rod is provided inside the injection tube. The gavage needle includes a stainless steel gavage needle and a cover that is fitted around the outer edge of the stainless steel gavage needle. The cover is a trumpet-shaped structure with a round hole in the center. The round hole is fitted around the outer edge of the stainless steel gavage needle. A sponge ring is attached to the inner wall of the cover.

[0007] Further improvements include an elastic cover made of rubber, which has a certain degree of elasticity and toughness. The inner diameter of the circular hole on the cover is 0.1 mm smaller than the outer diameter of the stainless steel gavage needle, allowing the cover to be fitted onto the stainless steel gavage needle.

[0008] Further improvements include a mounting head with one end fixedly connected to and internally connected to a stainless steel gavage needle, and the other end having an internally threaded hole. The end of the injection tube has an external thread that mates with the internally threaded hole, ensuring a stable and airtight connection. A sealing ring is fixedly installed on the inner wall of the mounting head to improve the seal between the gavage needle and the injection tube, preventing drug leakage.

[0009] In a further improvement, a piston is provided at one end of the push rod, which is slidably connected to the inner wall of the injection tube to form a sealed piston chamber. The other end of the push rod is provided with anti-slip texture to increase hand friction, facilitate operation, slow down the speed at which the drug enters the mouse's digestive tract, and avoid adverse reactions in the mouse.

[0010] A further improvement is made to the stainless steel gavage needle, which has a spherical tip. This avoids the difficulty of gavage caused by excessively high viscosity of the compound drug solution, facilitates the entry of the stainless steel gavage needle into the mouse, and reduces the possibility of esophageal damage.

[0011] Further improvements include a second graduation line on the side wall of the injection tube for precisely marking the volume of the traditional Chinese medicine compound solution, ensuring accurate dosage for each gavage. A first graduation line is located on one side of the stainless steel gavage needle, allowing operators to observe the depth of the needle insertion into the mouse and thus control the gavage depth.

[0012] A further improvement is made by coating the outer edge of the stainless steel gavage needle with a PTEF membrane. PTEF is currently the material used for disposable gavage needles; it is elastic, flexible, and causes minimal damage to the animal's mucous membrane, but it cannot be reused. Stainless steel gavage needles can be reused, but they are prone to damaging the mucous membrane. Coating the outer edge of the stainless steel gavage needle with a PTEF membrane combines the advantages of both.

[0013] The beneficial effects of this utility model are as follows:

[0014] 1. The cover is trumpet-shaped, which helps to keep the mouse's neck upright during gavage, preventing the gavage needle from accidentally entering the mouse's trachea and reducing the possibility of experimental personnel being accidentally bitten or injured by the animal.

[0015] 2. The sponge ring covers the mouse's mouth during gavage to prevent the medication from spilling out, while also providing some cushioning to reduce the mouse's discomfort.

[0016] 3. One end of the stainless steel gavage needle is spherical, which can avoid the compound drug solution being too viscous, making it difficult to administer the medication. This facilitates the entry of the stainless steel gavage needle into the mouse and reduces the possibility of esophageal damage.

[0017] 4. It is particularly suitable for oral administration experiments of compound Chinese medicine solutions and can be used repeatedly. Attached Figure Description

[0018] To more clearly illustrate the technical solutions in the embodiments of this utility model, the drawings used in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0019] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0020] Figure 2 This is a schematic diagram showing the connection between the injection tube and the gavage needle;

[0021] Figure 3 This is a schematic diagram of the cover structure;

[0022] Figure 4 This is a cross-sectional view of the cover structure.

[0023] In the diagram, 1. Injection tube; 2. Gavage needle; 3. Mounting head; 4. Stainless steel gavage needle; 5. Cover; 6. Push rod; 7. Sponge ring; 8. Round hole; 9. External thread; 10. First graduation line; 11. Second graduation line. Detailed Implementation

[0024] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of the present utility model.

[0025] Reference Figure 1-4 An enema device includes a syringe portion and a shielding mechanism portion. The syringe tube 1 is made of transparent material to facilitate observation of the volume of the traditional Chinese medicine compound solution. One end of the syringe tube 1 is designed with an external thread 9 for threaded connection with the enema needle 2, ensuring a stable and airtight connection.

[0026] The gavage needle 2 includes a stainless steel gavage needle 4, which is connected to the injection tube 1 via a mounting head 3. The inner wall of the mounting head 3 has internal threads that match the external threads 9 of the injection tube 1, ensuring a tight connection. To improve the seal between the gavage needle 2 and the injection tube 1 and prevent drug leakage, a sealing ring is fixedly installed on one side of the inner wall of the mounting head 3. One end of the stainless steel gavage needle 4 is fixedly connected to and communicates with the mounting head 3, ensuring smooth flow of the drug. The other end of the stainless steel gavage needle 4 is designed as a spherical shape to avoid excessively viscous compound drug solutions, which could lead to difficulties in gavage and facilitate entry of the stainless steel gavage needle into the mouse, reducing the possibility of esophageal damage. A piston is slidably connected to the inner wall of the injection tube 1, forming a sealed piston chamber. One end of the push rod 6 is fixedly connected to the piston, while the other end is provided with anti-slip texture to increase hand friction. This helps keep the head and neck upright during the gavage of mice, avoids the gavage needle from entering the trachea of ​​the mice, and reduces the risk of accidental bites or injuries to the experimental operators. At the same time, the conical design also better adapts to the shape of the mouse's mouth.

[0027] The injection tube 1 has a second graduation line 11 on one side, which is used to accurately mark the volume of the traditional Chinese medicine compound liquid to ensure that the dosage is accurate each time it is administered by gavage. In addition, the stainless steel gavage needle 4 also has a first graduation line 10 on one side, which makes it easy for the operator to observe the depth of the gavage needle 2 entering the mouse's body, thereby controlling the depth of gavage.

[0028] The stainless steel gavage needle is covered with a PTEF membrane on its outer edge. PTEF is currently the material used for disposable gavage needles. It is elastic, flexible, and causes minimal damage to the animal's mucous membrane, but it cannot be reused. Stainless steel gavage needles can be reused, but they are prone to damaging the mucous membrane. By placing a PTEF membrane inside the stainless steel gavage needle, the advantages of both stainless steel gavage needles and PTEF membranes are combined.

[0029] To address the issue of poor adhesion between the PTFE membrane and the stainless steel gavage needle, this embodiment uses FS-203A adhesive to bond the PTFE membrane to the stainless steel gavage needle. FS-203A adhesive is a silicone pressure-sensitive adhesive, a water-based, one-component solvent-based adhesive with the following three main characteristics: 1. Non-toxic, with good water resistance, high and low temperature resistance, and high adhesion. 2. No special surface treatment is required for the PTFE membrane when bonding it. 3. The bonding process is simple, economical, and highly practical.

[0030] Shielding Mechanism: The cover 5 is made of rubber, possessing a certain degree of elasticity and toughness. A circular hole 8 is located at the center of the cover 5. The diameter of the hole 8 is slightly smaller than the diameter of the stainless steel gavage needle 4 (0.1 mm), allowing the cover 5 to fit over the needle. The cover 5 is designed in a conical shape to help keep the mouse's head and neck upright during gavage, preventing accidental biting or injury to the operator. The conical design also better accommodates the shape of the mouse's mouth. One side of the sponge ring 7 is fixedly connected to the inner wall of the cover 5 and is also conical in design. The function of the sponge ring 7 is to shield the mouse's mouth during gavage, preventing spillage of the medication, and providing cushioning to reduce discomfort for the mouse.

[0031] The various embodiments in this specification are described in a progressive manner. Similar or identical parts between embodiments can be referred to interchangeably. Each embodiment focuses on its differences from other embodiments. In particular, for the device embodiments, the above descriptions are merely preferred embodiments of this utility model. Since they are fundamentally similar to the method embodiments, the descriptions are relatively simple; relevant parts can be referred to the descriptions of the method embodiments. The above descriptions are merely specific embodiments of this utility model, but the protection scope of this utility model is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the scope of the technology disclosed in this utility model, without departing from the principle of this utility model, should be included within the protection scope of this utility model. Therefore, the protection scope of this utility model should be determined by the scope of the claims.

Claims

1. A gavage device, comprising an injection tube and a gavage needle connected via an attachment head, wherein a push rod is disposed within the injection tube, characterized in that: The gavage needle includes a stainless steel gavage needle and a cover that is fitted around the outer edge of the stainless steel gavage needle. The cover is a trumpet-shaped structure with a central hole. The hole fits around the outer edge of the stainless steel gavage needle, and a sponge ring is attached to the inner wall of the cover.

2. The gavage device according to claim 1, characterized in that: The cover is an elastic structure, and the inner diameter of the circular hole on the cover is 0.1 mm smaller than the outer diameter of the stainless steel gavage needle.

3. The gavage device according to claim 1, characterized in that: One end of the mounting head is fixedly connected to the stainless steel gavage needle and is internally connected, while the other end is provided with an internal threaded hole. The end of the injection tube is provided with an external thread that mates with the internal threaded hole.

4. The gavage device according to claim 3, characterized in that: A sealing ring is fixedly installed on the inner wall of the mounting head.

5. The gavage device according to claim 1, characterized in that: A piston is provided at one end of the push rod, and the piston is slidably connected to the inner wall of the injection tube to form a sealed piston chamber. The other end of the push rod is provided with anti-slip texture.

6. The gavage device according to claim 1, characterized in that: The tip of the stainless steel gavage needle is spherical.

7. The gavage device according to claim 1, characterized in that: The side wall of the injection tube is provided with a second scale line.

8. The gavage device according to claim 1, characterized in that: The stainless steel gavage needle has a first graduation line on one side.

9. The gavage device according to claim 1, characterized in that: The outer edge of the stainless steel gavage needle is covered with a PTEF membrane.

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