Tumor electric field treatment device and electrode plate thereof

Abstract

The utility model provides a tumor electric field treatment device and an electrode plate thereof, the electrode plate comprises a plurality of electrode units and a flexible circuit board, and the plurality of electrode units are divided into a plurality of row groups and a plurality of column groups in circuit connection; the flexible circuit board is configured to allow the plurality of electrode units to be arranged on the flexible circuit board at intervals, and a plurality of conductive traces are embedded in the flexible circuit board. The plurality of conductive traces comprise a plurality of grounding wires and a plurality of dual-purpose signal wires, and the grounding wires are electrically connected with all the row groups in a one-to-one correspondence mode and are configured to enable all the electrode units in the corresponding row groups to be short-circuited and grounded; the dual-purpose signal lines are electrically connected with all the column groups in a one-to-one correspondence mode and are configured to transmit alternating current electric signals to all the electrode units and transmit direct current electric signals to all the electrode units or transmit temperature detection signals detected by all the electrode units in the corresponding column groups. By arranging the dual-purpose signal line, the number of conductive traces on the electrode plate can be reduced, and then the number of wire cores of wires connected with the electrode plate is reduced.

Description

TECHNICAL FIELD

[0001] The present application relates to tumor treating fields (TTF) technology, and in particular to a tumor treating fields device and an electrode sheet thereof. BACKGROUND

[0002] Tumor treating fields is a method of treating tumors by low-intensity, high-frequency alternating electric fields, which prevents the formation of spindle microtubules in the mitotic process of some tumor cells, inhibits the separation of intracellular organelles in the cell division phase, and induces apoptosis of cells in the mitotic phase, thereby achieving the effect of treating tumors.

[0003] Compared with traditional cancer treatment methods, TTF has an innovative mechanism of action. Some physiological characteristics of tumor cells, such as geometry and high-frequency mitosis, make them susceptible to TTF. TTF disrupts the normal aggregation of tubulin by exerting a directional force on intracellular polar particles (such as macromolecules and organelles). These processes can lead to physical disruption of the cell membrane and apoptosis. At the end of the cell mitosis, the structure of the cleavage furrow leads to uneven distribution of the electric field around it, and under the influence of TTF, the electric field intensity at the cleavage furrow is significantly enhanced, and the charged substances in the cell move towards the cleavage furrow, which interferes with the formation of the cell structure and even destroys it, ultimately leading to cell division failure and apoptosis.

[0004] In existing tumor treating fields devices, an electric field application device is used to transmit an alternating current signal for tumor treating fields to an electrode sheet, and then an alternating electric field is applied to the tumor site of a patient through the electrode sheet for tumor treating fields. When the tumor treating electric field is applied to the patient's body, heat will accumulate at the application site, and the temperature will also rise accordingly. Therefore, it is necessary to monitor the temperature at the application site, and when the temperature is too high, the electric field intensity needs to be adjusted in time to avoid the risk of skin burns caused by excessive temperature.

[0005] The tumor electric field treatment device includes at least one pair of electrode sheets, and each electrode sheet includes a plurality of electrode units. Even if the same alternating current signal is applied to each electrode unit, the heat generated on each electrode unit will be different due to the different positions of the electrode units, and the temperature of each electrode unit on the entire electrode sheet will not be completely uniform. Thus, the temperature of some electrode units on the entire electrode sheet may exceed the preset temperature, while the temperature of other electrode units is normal. In order to ensure that the tumor electric field treatment has a long enough application time while avoiding causing low-temperature burns on the surface of the patient's body, individual control of the over-temperature electrode units is required. However, for the existing electrode sheet, individual control of the electrode units requires that a conductive trace be provided for each electrode unit in the substrate of the electrode sheet. This will increase the number of conductive traces in the electrode sheet substrate, making the electrode sheet difficult to bend, and the cable electrically connected to the electrode sheet will also be thickened, which will increase the overall weight of the electrode sheet and is not conducive to the application of the electrode sheet.

[0006] Therefore, it is necessary to provide a tumor electric field treatment device and an electrode sheet thereof for partition control of a plurality of electrode units using fewer conductive traces. Practical new type content

[0007] An object of the present application is to provide a tumor electric field treatment device and an electrode sheet thereof to solve or eliminate the problems in the related art.

[0008] To achieve the above object, the present application provides the following technical solution. An electrode sheet includes a plurality of electrode units, the plurality of electrode units are divided into a plurality of row groups and a plurality of column groups in circuit connection, the number of row groups of the electrode units is 3, and the number of column groups of the electrode units is 5 or the number of row groups and the number of column groups of the electrode units are both 4, and a flexible circuit board configured to have the plurality of electrode units arranged thereon, and the flexible circuit board has a plurality of conductive traces embedded therein, the plurality of conductive traces include a plurality of ground lines and a plurality of dual-purpose signal lines, the ground lines are electrically connected to each row group of the electrode units in a one-to-one correspondence, each ground line is configured to short the corresponding parts of each electrode unit in the corresponding row group to ground, and the dual-purpose signal lines are electrically connected to each column group of the electrode units in a one-to-one correspondence, each dual-purpose signal line is configured to transmit an alternating current signal to each electrode unit in the corresponding column group, transmit a direct current signal to each electrode unit in the corresponding column group, or transmit a temperature detection signal detected by each electrode unit in the corresponding column group.

[0009] The electrode sheet for tumor electric field treatment divides a plurality of electrode units into a plurality of row groups and a plurality of column groups, and each electrode unit in each row group is short-circuited through the same ground wire, and each electrode unit in each column group realizes transmission of alternating current signal and transmission of direct current signal or acquisition of temperature detection signal of each electrode unit through the same dual-purpose signal line, so that the temperature detection coverage rate of 100% of the electrode units can be achieved without increasing the conductive trace of the electrode sheet, the weight of the electrode sheet is avoided to be too large, and the application effect of the electrode sheet is maintained; in addition, the number of wire traces of the flexible circuit board of the electrode sheet is reduced, the manufacturing process is simplified, and the manufacturing cost is reduced.

[0010] Further, the number of the dual-purpose signal lines is equal to the number of the column groups in which the electrode units are divided, and / or the number of the ground wires is equal to the number of the row groups in which the electrode units are divided.

[0011] Further, the flexible circuit board is provided with a plurality of connecting portions, the plurality of electrode units are 13 and arranged in 5 rows in structure, 2 electrode units are arranged in each of the first and last rows, and 3 electrode units are arranged in each of the middle three rows, wherein a space is formed between the 2 electrode units in the first or last row, and / or a space is formed between part of the electrode units in the middle three rows and the adjacent electrode units.

[0012] Further, each electrode unit includes a dielectric element for transmitting alternating current signal and a temperature sensor for detecting the temperature of the corresponding electrode unit and having a signal end and a ground end, and the dielectric element of each electrode unit is short-circuited with the signal end of the temperature sensor.

[0013] Further, only one of the plurality of ground wires is turned on at the same time when the electrode units perform temperature detection, and the rest of the plurality of ground wires are turned off, and all of the plurality of dual-purpose signal lines are turned on when the electrode units perform temperature detection; or all or part of the plurality of dual-purpose signal lines are turned on when the electrode units apply alternating current signal, and all of the plurality of ground wires are turned off when the electrode units apply alternating current signal.

[0014] To achieve the above purpose, the application further provides the following technical solutions, a tumor electric field treatment device comprising at least one pair of the above electrode sheet.

[0015] Further, the electric field generator is configured to provide an alternating current signal to the multiple electrode units of the electrode sheet via the dual-purpose signal lines of the electrode sheet, and the adapter is connected between the electrode sheet and the electric field generator, configured to deliver the alternating current signal generated by the electric field generator to the multiple dual-purpose signal lines of the electrode sheet, and further configured to receive the temperature detection signal output by the multiple dual-purpose signal lines of the electrode sheet, the adapter comprising: an AC signal line configured to provide an alternating current signal to each of the electrode units in the corresponding column group via the multiple dual-purpose signal lines.

[0016] Further, the adapter further comprises: multiple groups of grounding switches, each group of grounding switches being electrically connected to a corresponding electrode sheet and comprising multiple grounding switches, the multiple grounding switches being electrically connected to the multiple ground lines of the corresponding electrode sheet one by one and being configured to control the conduction or disconnection of the multiple ground lines.

[0017] Further, the adapter further comprises: multiple groups of analog-to-digital converters, each group of analog-to-digital converters being electrically connected to the multiple dual-purpose signal lines of a corresponding electrode sheet and being configured to receive the temperature detection signal transmitted by the multiple dual-purpose signal lines of the corresponding electrode sheet and convert the temperature detection signal from an analog signal to a digital signal, wherein each group of analog-to-digital converters comprises multiple detection channels, each detection channel being used to connect a corresponding dual-purpose signal line in the multiple dual-purpose signal lines; and multiple groups of bidirectional switching switches, each group of bidirectional switching switches corresponding to a multiple electrode sheet one by one, each group of bidirectional switching switches comprising multiple bidirectional switching switches, the multiple bidirectional switching switches being electrically connected to the multiple dual-purpose signal lines of the corresponding electrode sheet one by one; wherein each bidirectional switching switch further has a 1 terminal electrically connected to a corresponding detection channel in a corresponding analog-to-digital converter and a 2 terminal electrically connected to the AC signal line.

[0018] Further, the adapter further comprises: a first controller connected to the multiple groups of grounding switches and the multiple groups of bidirectional switching switches, and configured to: control the opening and closing states of the multiple grounding switches in turn to individually conduct each ground line of the multiple ground lines of the corresponding electrode sheet in turn; and control the switching states of the multiple bidirectional switching switches to place the bidirectional switching switches at the 1 terminal to output the temperature detection signal or place the bidirectional switching switches at the 2 terminal to transmit the alternating current signal.

[0019] The above description is only a summary of the technical solutions of the present application, in order to more clearly understand the technical means of the present application, the specific embodiments of the present application can be implemented according to the content of the description, and in order to make the above and other purposes, features and advantages of the present application more obvious and easy to understand, the following specific embodiments of the present application are described. BRIEF DESCRIPTION OF DRAWINGS

[0020] Figure 1 This is a schematic diagram of the tumor electric field therapy device of this application;

[0021] Figure 2 For this application Figure 1 Schematic diagrams of two other structural forms of the electrode pads in the tumor electric field therapy device shown;

[0022] Figure 3 For this application Figure 1 A schematic diagram of the circuit connection between the electrode pads and the adapter in the first embodiment of the tumor electric field system shown;

[0023] Figure 4 for Figure 3 A schematic block diagram of the internal structure of the adapter in the first embodiment shown;

[0024] Figure 5 For this application Figure 1 A schematic block diagram of the internal structure of the electric field generator in the tumor electric field therapy device shown;

[0025] Figure 6 For this application Figure 1 The electrode plates of the second embodiment of the tumor electric field system shown are... Figure 3 The circuit connection diagram of the adapter shown is shown;

[0026] Figure 7 For this application Figure 1 The electrode plates of the third embodiment of the tumor electric field system shown are... Figure 3 The circuit connection diagram of the adapter shown is shown;

[0027] Figure 8 For this application Figure 1 The electrode plates of the fourth embodiment of the tumor electric field system shown are... Figure 3 The circuit connection diagram of the adapter shown is shown;

[0028] Figure 9 For this application Figure 1 The electrode plates of the first embodiment of the tumor electric field system shown are... Figure 3 The circuit connection diagram of the adapter-transformation embodiment shown in the figure;

[0029] Figure 10 For this application Figure 1 The electrode plates of the second embodiment of the tumor electric field system shown are... Figure 9 The circuit connection diagram of the adapter shown is shown;

[0030] Figure 11 for Figure 9 A schematic block diagram of the internal structure of the adapter shown;

[0031] Figure 12 For this application Figure 1 The electrode plates of the third embodiment of the tumor electric field system shown are... Figure 3 A circuit connection diagram of another variant embodiment of the adapter shown;

[0032] Figure 13 For this application Figure 1 The electrode plates of the fourth embodiment of the tumor electric field system shown are... Figure 12 The circuit connection diagram of the adapter shown is shown;

[0033] Figure 14 for Figure 12 The diagram shows a schematic block diagram of the internal structure of the adapter.

[0034] Explanation of reference numerals in the attached figures:

[0035] Tumor electric field therapy device 100, electrode pads 10, flexible circuit board 11, electrode unit 12, first cable 13, temperature sensor 14, grounding terminal 14-1, signal terminal 14-2, dielectric element 15, diode 16, connector 17, grounding wire 18, first grounding wire 18-1, second grounding wire 18-2, third grounding wire 18-3, fourth grounding wire 18-4, dual-purpose signal line 19, first dual-purpose signal line 19-1, second dual-purpose signal line 19-2, third dual-purpose signal line 19-3, fourth dual-purpose signal line 19-4, fifth dual-purpose signal line 19-5, adapter 20, second cable 21, first controller 22, analog-to-digital converter 23, voltage divider resistor 24, grounding switch 25. First grounding switch 25-1, second grounding switch 25-2, third grounding switch 25-3, fourth grounding switch 25-4, bidirectional switch 26, first bidirectional switch 26-1, second bidirectional switch 26-2, third bidirectional switch 26-3, fourth bidirectional switch 26-4, fifth bidirectional switch 26-5, first communication unit 27, AC signal line 28, first power module 29, electric field generator 30, second power module 31, second controller 32, second communication unit 33, AC signal generator 34, AC signal switch 35, first connector 40, first plug 41, first socket 42, second connector 50, second plug 51, second socket 52. Detailed Implementation

[0036] The embodiments of the technical solution of this application will now be described in detail with reference to the accompanying drawings. These embodiments are only used to more clearly illustrate the technical solution of this application and are therefore merely examples, and should not be used to limit the scope of protection of this application.

[0037] Figure 1A schematic diagram of a tumor electric field therapy device 100 according to the present application is shown. As Figure 1 As shown, the tumor electric field therapy device 100 comprises at least one pair of electrode sheets 10, an adapter 20 connected to the electrode sheets 10, and an electric field generator 30 connected to the adapter 20. The electric field generator 30 supplies power to the electrode sheets 10 so that the electrode sheets 10 generate a therapeutic electric field. The adapter 20 is electrically connected between the electrode sheets 10 and the electric field generator 30, and is used to deliver an alternating current signal generated by the electric field generator 30 to the electrode sheets 10. That is, the electric field generator 30 is capable of generating an alternating current signal, and the alternating current signal generated thereby is transmitted to each of the electrode sheets 10 through the adapter 20, so that a therapeutic electric field for treating a tumor is generated between the same pair of electrode sheets 10. As Figure 1 As shown, in the present embodiment, the number of electrode sheets 10 is four. Each of the electrode sheets 10 includes a plurality of electrode units 12 in the same number, and each of the electrode units 12 is electrically connected to the adapter 20. The number of electrode units 12 on each of the electrode sheets 10 is thirteen. In other embodiments, the tumor electric field therapy device 100 can also have more or fewer electrode sheets 10. In other embodiments, each pair of electrode sheets 10 has the same number of electrode units 12, and different pairs of electrode sheets 10 can also have different numbers of electrode units 12.

[0038] Figure 3 A schematic diagram of the electrical connection between the electrode sheet 10 of the first embodiment of the tumor electric field therapy device 100 and the adapter 20 of the first embodiment is shown. It is worth noting that: Figure 3 As shown is the circuit arrangement of the electrode unit 12, in order to more clearly show the electrical connection between one of the electrode sheets 10 and the adapter 20, Figure 3 The arrangement of the electrode unit 12 shown does not represent the spatial arrangement of the electrode unit 12. In combination with Figures 1 to 3 The electrode sheet 10 includes a flexible circuit board 11, a plurality of electrode units 12 spaced apart and electrically connected to the flexible circuit board 11, and a first cable 13 electrically connected to the flexible circuit board 11. The flexible circuit board 11 is embedded with a plurality of conductive traces (18, 19), including a plurality of ground lines 18 and a plurality of dual-purpose signal lines 19. The first cable 13 has a plurality of conductive wires (not shown) electrically connected to the plurality of ground lines 18 and the plurality of dual-purpose signal lines 19 of the flexible circuit board 11 one by one. The total number of the ground lines 18 and the dual-purpose signal lines 19 embedded in the flexible circuit board 11 is not more than 10. Thus, the number of conductive wires of the first cable 13 is not more than 10.

[0039] In this embodiment, each electrode sheet 10 has 13 electrode units 12. These 13 electrode units 12 are grouped in the order of 1 to 13 in the circuit connection, forming three row groups and five column groups, i.e., the 13 electrode units 12 are arranged in three rows and five columns in the circuit connection. Each electrode unit 12 includes a dielectric element 15 and a temperature sensor 14. The temperature sensor 14 includes a ground terminal 14-1 and a signal terminal 14-2. Both the dielectric element 15 and the temperature sensor 14 are soldered onto the flexible circuit board 11, and the dielectric element 15 is short-circuited to the signal terminal 14-2 of the corresponding temperature sensor 14. Since multiple temperature sensors 14 are correspondingly arranged with multiple electrode units 12, the multiple temperature sensors 14 are also arranged in three rows and five columns in the circuit connection. It should be noted that this arrangement is for clearer illustration of the electrical connection between the electrode sheet 10 and the adapter 20, and does not represent the spatial arrangement of the electrode units 12. The spatial structure may be as follows: Figure 1 The structure shown is generally array-like, but it can also be other structures, such as petal-shaped or scattering-shaped, and can be regular or irregular. The dielectric element 15 is configured to apply an alternating electric field to the patient's tumor site. The temperature sensor 14 is configured to detect the temperature of the patient's body surface in contact with the electrode pad 10 and output a temperature detection signal to the adapter 20. In this embodiment, the multiplexed dual-purpose signal lines 19 of the flexible circuit board 11 are respectively arranged in a one-to-one correspondence with multiple columns of the electrode units 12, and are configured to transmit the AC signal generated by the electric field generator 30 to the dielectric element 15 in each electrode unit 12 in the corresponding column. That is, the dielectric elements 15 located in the same column are all short-circuited through the same dual-purpose signal line 19 of the flexible circuit board 11, and the dielectric elements 15 located in different columns are respectively connected in parallel through different dual-purpose signal lines 19 of the flexible circuit board 11. The dual-purpose signal lines 19 of the flexible circuit board 11 are electrically connected to the first cable 13, and then electrically connected to the electric field generator 30 via the adapter 20. Furthermore, the dual-purpose signal line 19 of the flexible circuit board 11 receives the AC signal generated by the electric field generator 30 through the first cable 13 and the adapter 20.

[0040] Multiple grounding wires 18 are respectively configured to correspond one-to-one with multiple rows of electrode units 12. Each grounding wire 18 is used to sequentially short-circuit and ground the temperature sensor 14 of each corresponding electrode unit 12 in each row. That is, the grounding terminals 14-1 of multiple temperature sensors 14 located in the same row are all short-circuited through the same grounding wire 18 of the flexible circuit board 11, and the grounding terminals 14-1 of temperature sensors 14 located in different row groups are connected in parallel through different grounding wires 18 of the flexible circuit board 11. During the temperature detection period, only one of the multiple grounding wires 18 is conductive at any given time, while the others are disconnected.

[0041] Each of the multiplexed dual-purpose signal lines 19 is also configured to short the signal end 14-2 of the temperature sensor 14 of at most one electrode unit 12 in each row group to an external device for receiving a detection signal, wherein the signal end 14-2 of the temperature sensor 14 connected by each of the multiplexed dual-purpose signal lines 19 is different from each other to avoid subsequent output of repeated signals by the dual-purpose signal lines 19. That is, when the number of electrode units 12 in a certain row group is equal to the number of the multiplexed dual-purpose signal lines 19, each of the multiplexed dual-purpose signal lines 19 is electrically connected to the signal end 14-2 of the temperature sensor 14 of a different electrode unit 12 in the row group, respectively. When the number of electrode units 12 in a certain row group is less than the number of the multiplexed dual-purpose signal lines 19, there is at least one multiplexed dual-purpose signal line 19 that is not electrically connected to the signal end 14-2 of the temperature sensor 14 of the electrode unit 12, and the remaining multiplexed dual-purpose signal lines 19 are electrically connected to the signal end 14-2 of the temperature sensor 14 of a different electrode unit 12 in the row group, respectively. In the present embodiment, the external device for receiving a detection signal is the adapter 20. The signal ends 14-2 of the plurality of temperature sensors 14 located in different column groups are connected in parallel through different multiplexed dual-purpose signal lines 19 of the flexible circuit board 11, respectively, and the signal ends 14-2 of the plurality of temperature sensors 14 located in the same column group are all shorted to the same multiplexed dual-purpose signal line 19 of the flexible circuit board 11.

[0042] In the present embodiment, in the case where the temperature sensor 14 is configured in each electrode unit 12 for temperature detection, the above-mentioned line design is used to reduce the number of conductive lines of the first cable 13, avoid thickening of the cable, hardening of the softness of the cable, and increase the difficulty of fixing the cable; at the same time, the increase in the number of conductive lines of the first cable 13 avoids affecting the adhesion effect between the electrode sheet 10 and the corresponding body surface of the tumor site of the patient. The embedded ground lines 18 and the multiplexed dual-purpose signal lines 19 in the flexible circuit board 11 are a total of 8 lines. Specifically, in the present embodiment, the embedded ground lines 18 in the flexible circuit board 11 are 3 lines, and the multiplexed dual-purpose signal lines 19 are 5 lines. In other embodiments, the embedded ground lines 18 in the flexible circuit board 11 are 4 lines, and the multiplexed dual-purpose signal lines 19 are 4 lines. In the tumor electric field treatment device 100, the number of conductive lines electrically connected to the ground lines 18 is related to the number of row groups M of the electrode units 12, which can be greater than or equal to the number of row groups M of the electrode units 12, and M is a positive integer. In the tumor electric field treatment device 100, the number of conductive lines electrically connected to the multiplexed dual-purpose signal lines 19 is related to the number of column groups N of the electrode units 12, which can be greater than or equal to the number of column groups N of the electrode units 12, and N is a positive integer. The number of lines L embedded in the flexible circuit board 11 of the electrode sheet 10 is equal to the sum of the number of ground lines 18 and the number of multiplexed dual-purpose signal lines 19. In the present embodiment, the number of ground lines 18 is equal to the number of row groups M of the electrode units 12; the number of multiplexed dual-purpose signal lines 19 is equal to the number of column groups N of the electrode units 12.

[0043] A plurality of electrode units 12 are arranged in a substantially two-dimensional array on the flexible circuit board 11. As shown in Figure 1 In the embodiment shown, the electrode sheet 10 includes 13 electrode units 12 and 13 temperature sensors 14 corresponding to the electrode units 12, the 13 electrode units 12 are arranged in a five-by-five array, with 2 electrode units in the first and last rows and 3 electrode units in the middle three rows. The 4 electrode units in the first and last rows are arranged in two columns. The 9 electrode units in the middle three rows are arranged in three columns, staggered with the two columns formed by the electrode units in the first and last rows. The flexible circuit board 11 is provided with a plurality of connecting portions 17, each electrode unit 12 is connected to all adjacent electrode units 12 via the connecting portions 17. In other forms of the electrode sheet 10, some electrode units 12, especially those located at the periphery, can be spaced apart from adjacent electrode units 12 without connecting portions 17 therebetween. As shown in Figure 2 The electrode sheet 10' and the electrode sheet 10" are spaced apart by a distance D1 between the 2 electrode units in the first and last rows thereof, and are spaced apart by a distance D2 between some electrode units in the middle three rows thereof and adjacent electrode units thereof. The distances D1 and D2 are arranged to prevent the electrode sheet 10' and the electrode sheet 10" from being wrinkled due to some body movements of the patient when the electrode sheet 10' and the electrode sheet 10" are attached to the patient, which can affect the overall attachment effect and further adversely affect the treatment effect.

[0044] In some other embodiments, the 13 electrode units 12 can be arranged in other ways. Of course, in some other embodiments, the electrode sheet 10 can have other numbers of electrode units 12. In general, the implementation of the present application is not limited by the number and arrangement of the electrode units 12 of the electrode sheet 10.

[0045] Each electrode unit 12 includes a dielectric element 15 and a temperature sensor 14. In Figure 3 In the embodiment shown, the dielectric element 15 can be a dielectric ceramic sheet or a high-molecular dielectric layer formed of a high-molecular material. The temperature sensor 14 can be a thermistor element, of course, in some other embodiments, the temperature sensor 14 can be other temperature sensors other than thermistors, which can be arranged at any position on the electrode unit 12. In the present embodiment, each dielectric element 15 has a through hole (not numbered) formed in the middle thereof, and each dielectric element 15 has a corresponding temperature sensor 14 received in the through hole (not numbered) thereof. Each electrode unit 12 can further include a diode 16. The diode 16 is connected in series with the temperature sensor 14 of the same electrode unit 12, which can prevent reverse current from flowing in to prevent the detection signal from other electrode units 12 from affecting the temperature sensor 14.

[0046] Figure 3As shown, the electrode sheet 10 of the present embodiment includes three ground lines 18, each of which is used to ground the ground terminals 14-1 of the temperature sensors 14 in the same row group. The three ground lines 18 of the electrode sheet 10 are respectively a first ground line 18-1, a second ground line 18-2, and a third ground line 18-3. In the three row groups of the electrode sheet 10, the first row group is the electrode units 12-1 to 12-5, the second row group is the electrode units 12-6 to 12-10, and the third row group is the electrode units 12-11 to 12-13. Specifically, the first ground line 18-1 is used to ground the electrode units 12-1 to 12-5 in the first row group; the second ground line 18-2 is used to ground the electrode units 12-6 to 12-10 in the second row group; and the third ground line 18-3 is used to ground the electrode units 12-11 to 12-13 in the third row group. It should be noted that these ground lines 18 are selectively closable or disconnectable, which can be achieved by connecting each ground line 18 in series with a switch, which will be described in detail below. The above-mentioned "grounding the electrode units 12" can refer to grounding the ground terminals 14-1 of the temperature sensors 14 in the electrode units 12, or can refer to connecting the diodes 16 in series with the temperature sensors 14 of the same electrode units 12 and grounding them together. In short, each ground line 18 shorts and grounds the ground terminals 14-1 of the temperature sensors 14 of all the electrode units 12 in each row group.

[0047] Figure 3As shown, the electrode sheet 10 of the present embodiment also includes five two-way signal lines 19, one end of each of the two-way signal lines 19 is connected to all the electrode units 12 in each column group, and the other end is connected to an adapter 20 for receiving temperature detection signals and transmitting alternating current signals. That is, for each row group, each of the two-way signal lines 19 can selectively connect one of the electrode units 12 or none of the electrode units 12 in the row group to avoid subsequent output of duplicate signals from the two-way signal lines 19. Specifically, the five two-way signal lines 19 of the electrode sheet 10 include a first two-way signal line 19-1, a second two-way signal line 19-2, a third two-way signal line 19-3, a fourth two-way signal line 19-4, and a fifth two-way signal line 19-5. One end of the first two-way signal line 19-1 is simultaneously connected to the signal end 14-2 of the temperature sensor 14 and the dielectric element 15 of each of the three electrode units 12-1, 12-6, and 12-11; one end of the second two-way signal line 19-2 is simultaneously connected to the signal end 14-2 of the temperature sensor 14 and the dielectric element 15 of each of the three electrode units 12-2, 12-7, and 12-12; one end of the third two-way signal line 19-3 is simultaneously connected to the signal end 14-2 of the temperature sensor 14 and the dielectric element 15 of each of the three electrode units 12-3, 12-8, and 12-13; one end of the fourth two-way signal line 19-4 is simultaneously connected to the signal end 14-2 of the temperature sensor 14 and the dielectric element 15 of each of the two electrode units 12-4 and 12-9; and one end of the fifth two-way signal line 19-5 is simultaneously connected to the signal end 14-2 of the temperature sensor 14 and the dielectric element 15 of each of the two electrode units 12-5 and 12-10. In short, each of the two-way signal lines 19 parallelly connects the signal end 14-2 of the temperature sensor 14 and the dielectric element 15 of each of the electrode units 12 in the same column group and is used to connect to an external device. It is noted that the two-way signal lines 19 can selectively transmit alternating current signals or receive temperature detection signals, which can be achieved by connecting each of the two-way signal lines 19 in series with a bidirectional switch 26 and cooperating with the closing or opening of the ground line 18, which will be described in detail below.

[0048] The multiple ground lines 18 and the multiple two-way signal lines 19 are conductive traces embedded in the flexible circuit board 11. The flexible circuit board 11 is electrically connected to the first cable 13. The multiple ground lines 18 and the multiple two-way signal lines 19 embedded in the flexible circuit board 11 are respectively electrically connected to corresponding conductive lines (not shown) in the first cable 13.

[0049] The tumor electric field therapy device 100 of the present embodiment includes at least one pair of the above-mentioned electrode sheet 10, an adapter 20 electrically connected to the electrode sheet 10, and an electric field generator 30 electrically connected to the adapter 20. The adapter 20 is connected between the electrode sheet 10 and the electric field generator 30. The electric field generator 30 provides an alternating current signal to the dielectric element 15 in the plurality of electrode units 12 of the electrode sheet 10 via the adapter 20 and the dual-purpose signal line 19 of the electrode sheet 10 or receives a temperature detection signal output by the temperature sensor 14 in the plurality of electrode units 12. The adapter 20 is configured to deliver the alternating current signal generated by the electric field generator 30 to the dual-purpose signal line 19 of the electrode sheet 10 and is also configured to receive the temperature detection signal output by the plurality of dual-purpose signal lines 19 of the electrode sheet 10.

[0050] Reference Figure 3As shown, the adapter 20 comprises a first controller 22, a plurality of groups of analog-to-digital converters 23 connected to the first controller 22, a plurality of groups of voltage dividing resistors 24 and a plurality of groups of grounding switches 25 corresponding to the plurality of groups of analog-to-digital converters 23, a plurality of groups of bidirectional switches 26 connected to the plurality of groups of analog-to-digital converters 23, a first communication unit 27, a plurality of AC signal lines 28 connected to each group of bidirectional switches 26, and a first power module 29 connected to the first communication unit 27, the first controller 22, and the plurality of groups of analog-to-digital converters 23, the first power module 29 providing direct current power VCC for each electronic component of the adapter 20. The adapter 20 further comprises a plurality of circuit lines (not labeled). The plurality of circuit lines (not labeled) are respectively and electrically connected to the plurality of ground lines 18 and the plurality of dual-purpose signal lines 19 in the flexible circuit board 11 of the corresponding electrode sheet 10 through the first cable 13 of the electrode sheet 10. The plurality of circuit lines (not labeled) comprise a plurality of AC signal lines 28 respectively and electrically connected to the plurality of dual-purpose signal lines 19 in the flexible circuit board 11 of the corresponding electrode sheet 10 for transmitting AC signals to the corresponding electrode sheet 10, a plurality of circuit lines (not labeled) respectively and electrically connected to the plurality of dual-purpose signal lines 19 in the flexible circuit board 11 of the corresponding electrode sheet 10 for providing power to each temperature sensor 14 of the electrode sheet 10 or transmitting temperature detection signals of the electrode sheet 10, and a plurality of circuit lines (not labeled) respectively and electrically connected to the plurality of ground lines 18 in the flexible circuit board 11 of the corresponding electrode sheet 10. The number L of circuit lines electrically connected to the electrode sheet 10 by the adapter 20 is equal to the sum of the number M of rows and the number N of columns of the electrode units 12 of the electrode sheet 10 plus 1; the number H of circuits electrically connected to X electrode sheets 10 by the adapter 20 is equal to X times the number of circuit lines electrically connected to a single electrode sheet 10, i.e., H = XL = X*(M+N+1). The number of groups of grounding switches 25 and the number of groups of bidirectional switches 26 are both related to the number of electrode sheets 10. The number of groups of grounding switches 25 is the same as the number of groups of bidirectional switches 26; and is not less than the number of electrode sheets 10. Preferably, the number of groups of grounding switches 25 and the number of groups of bidirectional switches 26 are both the same as the number of electrode sheets 10. As an example, the electrical connection between an electrode sheet 10 having 13 electrode units 12 and the adapter 20 is described in detail below.

[0051] Each group of grounding switches 25 has multiple grounding switches 25, which are respectively connected to the adapter 20 and electrically connected to the circuit lines (unlabeled) corresponding one-to-one with the multiple grounding wires 18 of a corresponding electrode piece 10, and are configured to control the conduction or disconnection of the multiple grounding wires 18. The circuit lines (unlabeled) that are each electrically connected to the multiple grounding wires 18 of the electrode piece 10 are grounded at the end closest to the grounding switch 25. The number of grounding switches 25 in each group of grounding switches 25 is related to the number of grounding wires 18 on the flexible circuit board 11 of the corresponding electrode piece 10; in this embodiment, the two are not equal. Figure 3 As shown, in this embodiment, each group of grounding switches 25 includes a first grounding switch 25-1, a second grounding switch 25-2, a third grounding switch 25-3, and a fourth grounding switch 25-4. Each of the multiple grounding switches 25 in each group controls the closing or opening of the corresponding grounding wire 18 of a corresponding electrode plate 10. Specifically, the first grounding switch 25-1 is used to control the opening or closing of the first grounding wire 18-1 of the corresponding electrode plate 10, and can cooperate with the corresponding set of bidirectional switching switches 26 to control the power supply and de-energization of each temperature sensor 14 of the five electrode units 12 in the first row group of the electrode plate 10, from electrode unit 12-1 to electrode unit 12-5; the second grounding switch 25-2 is used to control the opening or closing of the second grounding wire 18-2 of the electrode plate 10, and can cooperate with the corresponding set of bidirectional switching switches 26 to control the power supply and de-energization of each temperature sensor 14 of the five electrode units 12 in the second row group of the electrode plate 10, from electrode unit 12-6 to electrode unit 12-10; the third grounding switch 25-3 is used to control the opening or closing of the third grounding wire 18-3 of the electrode plate 10, and can cooperate with the corresponding set of bidirectional switching switches 26 to control the power supply and de-energization of each temperature sensor 14 of the three electrode units 12 in the third row group of the electrode plate 10, from electrode unit 12-11 to electrode unit 12-13. In this embodiment, since the electrode plate 10 only has a first grounding wire 18-1, a second grounding wire 18-2, and a third grounding wire 18-3, only the first grounding switch 25-1, the second grounding switch 25-2, and the third grounding switch 25-3 are electrically connected to the electrode plate 10. The fourth grounding switch 25-4 is in an idle and open state. That is, the first grounding switch 25-1, the second grounding switch 25-2, and the third grounding switch 25-3 are available, while the fourth grounding switch 25-4 is idle. The aforementioned grounding switch 25 can be a mechanical switch, such as a relay. The grounding switch 25 can also be an electronic switch, and each grounding switch 25 can be opened and closed by the first controller 22 of the adapter 20.

[0052] In the embodiment, each group of grounding switches 25 is an electronic switch. The first controller 22 is in communication connection with the groups of grounding switches 25, for sequentially and cyclically controlling the on-off state of each of the plurality of grounding switches 25 in each group of grounding switches 25, and in turn sequentially and individually conducting each of the plurality of grounding lines 18 of the corresponding electrode sheet 10 and cooperating with the switching of the corresponding bidirectional switching switch 26, to sequentially and time-divisionally collect the temperature of the patient's body surface detected by all the temperature sensors 14 on the electrode sheet 10. The number of each group of grounding switches 25 is greater than or equal to the number of the grounding lines 18 of the flexible circuit board 11 of the corresponding electrode sheet 10. In the embodiment, the number of each group of grounding switches 25 is greater than the number of the grounding lines 18 of the corresponding electrode sheet 10.

[0053] Each group of bidirectional switching switches 26 is provided with a plurality of bidirectional switching switches 26, and the plurality of bidirectional switching switches 26 in each group are respectively connected to the circuit lines (not labeled) corresponding to the plurality of dual-purpose signal lines 19 of the corresponding electrode sheet 10 in the adapter 20 and are respectively electrically connected to the circuit lines. The number of bidirectional switching switches 26 in each group of bidirectional switching switches 26 is related to the number of dual-purpose signal lines 19 of the flexible circuit board 11 of the corresponding electrode sheet 10, which is greater than or equal to the number of dual-purpose signal lines 19 of the flexible circuit board 11 of the corresponding electrode sheet 10. In the embodiment, the number of bidirectional switching switches 26 in each group of bidirectional switching switches 26 is equal to the number of dual-purpose signal lines 19 of the flexible circuit board 11 of the corresponding electrode sheet 10. Figure 3 Each bidirectional switching switch 26 has two ends labeled 1 and 2. The 1 end of each bidirectional switching switch 26 in the same group is electrically connected to the corresponding detection channel of the corresponding group of analog-to-digital converters 23, and the 2 end of each bidirectional switching switch 26 in the same group is electrically connected to the corresponding same AC signal line 28. Each bidirectional switching switch 26 is configured to control the connection of the plurality of dual-purpose signal lines 19 to the corresponding AC signal line 28 to transmit an alternating current signal or to the corresponding detection channel of the corresponding group of analog-to-digital converters 23 to receive the temperature detection signal output by the temperature sensor 14.

[0054] As shown in the embodiment, the first controller 22 is in communication connection with the groups of bidirectional switching switches 26, for sequentially and cyclically controlling the on-off state of each of the plurality of bidirectional switching switches 26 in each group of bidirectional switching switches 26, and in turn sequentially and individually conducting each of the plurality of grounding lines 18 of the corresponding electrode sheet 10 and cooperating with the switching of the corresponding bidirectional switching switch 26, to sequentially and time-divisionally collect the temperature of the patient's body surface detected by all the temperature sensors 14 on the electrode sheet 10. Figure 3As shown, taking the example of the electrical connection of one electrode sheet 10 with the adapter 20, in the present embodiment with 13 electrode units 12, the plurality of bidirectional switches 26 are respectively a first bidirectional switch 26-1, a second bidirectional switch 26-2, a third bidirectional switch 26-3, a fourth bidirectional switch 26-4, and a fifth bidirectional switch 26-5. The multiple bidirectional switches 26 in the same group respectively control the switching of a corresponding one of the multiple two-purpose signal lines 19 of the same electrode sheet 10 between the transmission of an alternating current signal and the transmission of a temperature detection signal. Specifically, the first bidirectional switch 26-1 is used to control the switching of the first two-purpose signal line 19-1 of the corresponding electrode sheet 10 between the transmission of an alternating current signal and the transmission of a temperature detection signal, thereby controlling the switching between the conduction of the dielectric element 15 of the electrode unit 12-1, the electrode unit 12-6, and the electrode unit 12-11 in the first column group of the electrode sheet 10 and the conduction of the signal end 14-2 of the temperature sensor 14 of the electrode unit 12-1, the electrode unit 12-6, and the electrode unit 12-11 in the first column group, and cooperating with the corresponding first grounding switch 25-1, the second grounding switch 25-2, and the third grounding switch 25-3, so that the first column of electrode units 12-1, 12-6, and 12-11 transmits an alternating current signal to a patient or outputs the temperature detection signal collected by the temperature sensor 14 of the electrode unit 12 to the corresponding analog-to-digital converter 23; the second bidirectional switch 26-2 is used to control the switching of the second two-purpose signal line 19-2 of the corresponding electrode sheet 10 between the transmission of an alternating current signal and the transmission of a temperature detection signal, thereby controlling the switching between the conduction of the dielectric element 15 of the electrode unit 12-2, the electrode unit 12-7, and the electrode unit 12-12 in the second column group of the electrode sheet 10 and the conduction of the signal end 14-2 of the temperature sensor 14 of the electrode unit 12-2, the electrode unit 12-7, and the electrode unit 12-12 in the second column group, and cooperating with the corresponding first grounding switch 25-1, the second grounding switch 25-2, and the third grounding switch 25-3, so that the second column of electrode units 12-2, 12-7, and 12-12 transmits an alternating current signal to a patient or outputs the temperature detection signal collected by the temperature sensor 14 of the electrode unit 12 to the corresponding analog-to-digital converter 23;The third bidirectional switch 26-3 is used to control the switching of the third dual-purpose signal line 19-3 of the corresponding electrode sheet 10 between transmitting the alternating current signal and transmitting the temperature detection signal, thereby controlling the switching between the conduction of the dielectric element 15 of each electrode unit 12-3, 12-8, 12-13 in the third column group of the electrode sheet 10 and the conduction of the signal end 14-2 of the temperature sensor 14 of each electrode unit 12-3, 12-8, 12-13 in the third column group, and cooperating with the corresponding first grounding switch 25-1, second grounding switch 25-2, and third grounding switch 25-3, so that the third column of electrode units 12-3, 12-8, 12-13 transmits the alternating current signal to the patient or outputs the temperature detection signal collected by the temperature sensor 14 of the electrode unit 12 to the corresponding analog-to-digital converter 23; the fourth bidirectional switch 26-4 is used to control the switching of the fourth dual-purpose signal line 19-4 of the corresponding electrode sheet 10 between transmitting the alternating current signal and transmitting the temperature detection signal, thereby controlling the switching between the conduction of the dielectric element 15 of each electrode unit 12-4, 12-9 in the fourth column group of the electrode sheet 10 and the conduction of the signal end 14-2 of the temperature sensor 14 of each electrode unit 12-4, 12-9 in the fourth column group, and cooperating with the corresponding first grounding switch 25-1 and second grounding switch 25-2, so that the fourth column of electrode units 12-4, 12-9 transmits the alternating current signal to the patient or outputs the temperature detection signal collected by the temperature sensor 14 of the electrode unit 12 to the corresponding analog-to-digital converter 23;The fifth bidirectional switch 26-5 is used to control the switching of the fifth dual-purpose signal line 19-5 of the corresponding electrode pad 10 between transmitting the alternating current signal and transmitting the temperature detection signal, thereby controlling the switching between the conduction of the dielectric element 15 of the electrode unit 12-5, electrode unit 12-10 in the fifth column group of the electrode pad 10 and the conduction of the signal end 14-2 of the temperature sensor 14 of the electrode unit 12-5, electrode unit 12-10 in the fifth column group, and cooperating with the corresponding first grounding switch 25-1, second grounding switch 25-2, so that the fifth column electrode unit 12-5, electrode unit 12-10 transmits the alternating current signal to the patient or outputs the temperature detection signal collected by the temperature sensor 14 of the electrode unit 12 to the corresponding analog-to-digital converter 23. When the 2 end of each group of bidirectional switch 26 is conductive and the 1 end is disconnected, the alternating current signal can be transmitted to the dielectric element 15 of each electrode unit 12 of the corresponding electrode pad 10, and when the 1 end of each group of bidirectional switch 26 is conductive and the 2 end is disconnected, it can be matched with each grounding switch 25 in the corresponding group of grounding switches 25 to transmit the temperature detection signal collected by the temperature sensor 14 of each electrode unit 12 on the electrode pad 10 in time. The bidirectional switch 26 described above can be a mechanical switch, such as a relay. The bidirectional switch 26 can also be an electronic switch, and the switching of the 1 end and the 2 end of each bidirectional switch 26 can be controlled by the first controller 22 of the adapter 20.

[0055] In the present embodiment, each group of bidirectional switch 26 is an electronic switch. The first controller 22 is in communication connection with the plurality of groups of bidirectional switch 26, and is used to control the switching of each group of bidirectional switch 26 between the 1 end and the 2 end, and cooperate with the closing or opening of the corresponding grounding switch 25, so as to continuously monitor the temperature of the patient's body surface detected by all the temperature sensors 14 on the electrode pad 10 or transmit the alternating current signal to the patient.

[0056] In this embodiment, each group of analog-to-digital converters 23 is electrically connected to one end of each of the multiple bidirectional switching switches 26 in the corresponding group through multiple circuit lines (unlabeled) within the adapter 20, and is configured to receive temperature detection signals transmitted from the multi-purpose signal lines 19 of the corresponding electrode sheet 10, and convert the temperature detection signals from analog signals to digital signals. Each group of analog-to-digital converters 23 includes multiple detection channels A, B, C, D, and E, each detection channel A, B, C, D, and E is used to connect to one corresponding multi-purpose signal line 19 in the multi-purpose signal lines 19 through the corresponding bidirectional switching switch 26. The number of detection channels in each group of analog-to-digital converters 23 is related to the number of bidirectional switching switches 26 in the corresponding group. The number of detection channels in each group of analog-to-digital converters 23 is related to the number of column groups of electrode units 12 of the corresponding electrode sheet 10. Specifically, the number of detection channels in each group of analog-to-digital converters 23 is equal to the number of bidirectional switching switches 26 in the corresponding group of bidirectional switching switches 26, and is not less than the number of column groups of electrode units 12 in the corresponding electrode sheet 10. For example... Figure 4 As shown, each group of analog-to-digital converters 23 includes five detection channels A, B, C, D, and E, which are respectively the first detection channel A, the second detection channel B, the third detection channel C, the fourth detection channel D, and the fifth detection channel E. The first detection channel A is connected to the first dual-purpose signal line 19-1 through terminal 1 of the first bidirectional switch 26-1; the second detection channel B is connected to the second dual-purpose signal line 19-2 through terminal 1 of the second bidirectional switch 26-2; the third detection channel C is connected to the third dual-purpose signal line 19-3 through terminal 1 of the third bidirectional switch 26-3; the fourth detection channel D is connected to the fourth dual-purpose signal line 19-4 through terminal 1 of the fourth bidirectional switch 26-4; and the fifth detection channel E is connected to the fifth dual-purpose signal line 19-5 through terminal 1 of the fifth bidirectional switch 26-5. Each detection channel A, B, C, D, and E is used to receive the temperature detection signal collected by the temperature sensor 14 of the electrode unit 12 connected to the corresponding dual-purpose signal line 19. In addition, each detection channel A, B, C, D, and E is connected to a first power supply module 29 via a corresponding voltage divider resistor 24 in the adapter 20. The first power supply module 29 provides DC power.

[0057] In the embodiment, the first communication unit 27 is configured to acquire the digital signals output by the plurality of groups of analog-to-digital converters 23 and send the digital signals to the electric field generator 30. The electric field generator 30 is also configured to control the voltage or current or power of the alternating current signal provided to the plurality of electrode units 12 of the electrode sheet 10 according to the received digital signals. For example, when any of the plurality of received digital signals exceeds a preset threshold value, it indicates that the temperature detected by at least one temperature sensor 14 of the electrode sheet 10 at the human body surface to which the dielectric element 15 is attached exceeds a preset threshold temperature (e.g., 41°C, 42°C, etc.), at which time the voltage or current or power of the alternating current signal output by the electric field generator 30 can be appropriately reduced to avoid the electrode units 12 of the electrode sheet 10 from being too hot when the alternating current signal is applied, causing a cold burn to the skin of the patient. The above-mentioned preset threshold temperature can be determined according to the safety threshold of the human body. The first communication unit 27 is controlled by the first controller 22 and serially transmits the digital signals converted by the plurality of groups of analog-to-digital converters 23. In the embodiment, the preset temperature threshold can be a value within 36°C-45°C.

[0058] Reference Figure 5 and Figure 1 In the embodiment, the first power supply module 29 is electrically connected to the second power supply module 31 of the electric field generator 30 and is configured to supply power to the first controller 22, the plurality of groups of analog-to-digital converters 23, and the first communication unit 27 of the adapter 20. A first connector 40 is provided between each electrode sheet 10 and the adapter 20, and the first connector 40 is adapted to connect the corresponding electrode sheet 10 to the adapter 20. As shown in Figure 5 The first connector 40 includes a first plug 41 provided at the end of the first cable 13 away from the electrode sheet 10 and a first socket 42 provided on the adapter 20, and the first plug 41 and the first socket 42 are press-type spring connectors, i.e., the first connector 40 connects the adapter 20 and the electrode sheet 10 in the form of a connector. Each first cable 13 has 5 wires electrically connected to the bidirectional switching switches 26-1, 26-2, 26-3, 26-4, 26-5 of the corresponding group of bidirectional switching switches 26 and 3 wires electrically connected to the grounding switches 25-1, 25-2, 25-3 of the corresponding group of grounding switches 25. That is, each first connector 40 is electrically connected to the corresponding group of bidirectional switching switches 26 and the corresponding group of grounding switches 25 of the adapter 20 through 8 wires, and is connected to the electric field generator 30 through the corresponding AC signal line 28 of the adapter 20.

[0059] The adapter 20 is provided with a second connector 50 adapted to connect the electric field generator 30 to the adapter 20. The adapter 20 further comprises a second cable 21 connected to the second connector 50. The second connector 50 comprises a second plug 51 provided at the end of the second cable 21 away from the first controller 22 and a second socket 52 provided on the electric field generator 30. The second plug 51 and the second socket 52 are press spring connectors, i.e. the second connector 50 connects the adapter 20 to the electric field generator 30 in the form of connectors. Each of the first connectors 40, such as X1, Y1, X2 and Y2, is connected to the second connector 50 through a corresponding AC signal line 28, and each of the first connectors 40, such as X1, Y1, X2 and Y2, is connected to a corresponding set of grounding switches 25 and a corresponding set of analog-digital converters 23, respectively. Each of the first connectors 40 is connected to the second connector 50 and a corresponding set of analog-digital converters 23 through a corresponding set of bidirectional switching switches 26, respectively. The second cable 21 has eight conductive wires, including four conductive wires 1-4 electrically connected to the corresponding AC signal lines 28 one by one and used for transmitting alternating current signals, one conductive wire 5 electrically connected to the data receiving line RX of the first communication unit 27, one conductive wire 6 electrically connected to the data sending line TX of the first communication unit 27, one conductive wire 7 electrically connected to the VCC power line of the first power module 29, and one conductive wire 8 electrically connected to the GND line of the first power module 29. The second connector 50 is connected to the first communication unit 27 through the data receiving line RX and the data sending line TX, the VCC pin of the second connector 50 is connected to the VCC power line of the first power module 29, the GND pin of the second connector 50 is connected to the GND line of the first power module 29 and grounded, and the VCC pin of the second connector 50 is further connected to the corresponding set of voltage dividing resistors 24 and the corresponding set of analog-digital converters 23 through the VCC power line of the first power module 29.

[0060] Reference Figures 3 to 5The electric field generator 30 comprises a second power module 31, a second controller 32, an AC signal generator 34, a second communication unit 33 and a group of AC signal switches 35. The VCC pin of the second connector 50 is also electrically connected with the VCC power line of the second power module 31, and the GND pin of the second connector 50 is grounded through the GND line of the second power module 31. The second power module 31 is also connected with and supplies power to the second controller 32 and the AC signal generator 34. The second communication unit 33 is electrically connected with the wire 5 of the second connector 50 through its data receiving line RX and is electrically connected with the wire 6 of the second connector 50 through its data sending line TX, so as to realize information interaction between the electric field generator 30 and the adapter 20. The second controller 32 is also electrically connected with the second communication unit 33, the AC signal generator 34 and the group of AC signal switches 35. The second controller 32 is configured to control the opening and closing of each AC signal switch 35 in the group of AC signal switches 35 and adjust the relevant parameters of the AC signal applied by the AC signal generator 34 according to the relevant digital signals received by the second communication unit 33 from the adapter 20. The AC signal generator 34 is electrically connected with the wires 1 to 4 of the second connector 50 through the group of AC signal switches 35. The group of AC signal switches 35 comprises a plurality of AC signal switches 35, which are arranged one-to-one corresponding to the plurality of electrode pieces 10. Each AC signal switch 35 is electrically connected with one wire 1, 2, 3 or 4 of the second connector 50 through one AC signal wire 36-1, 36-2, 36-3 or 36-4 and is electrically connected to the corresponding electrode piece 10 through the corresponding wire 1, 2, 3 or 4 of the second connector 50, so as to deliver the AC signal to each electrode piece 10. The AC signal generator 34 is electrically connected with the group of AC signal switches 35 through a group of AC signal wires 36. Specifically, the number of AC signal switches 35 of the electric field generator 30 is related to the number of electrode pieces 10. In the embodiment, the number of AC signal switches 35 is equal to the number of electrode pieces 10, and both are four. The AC signal switch 35 comprises a first AC signal switch 35-1, a second AC signal switch 35-2, a third AC signal switch 35-3 and a fourth AC signal switch 35-4, which are electrically connected with the wires 1 to 4 of the second connector 50 one-to-one respectively.The first AC signal switch 35-1 is electrically connected to the AC signal generator 34 through the AC signal wire 36 of the electric field generator 30 at one end, and is electrically connected to the corresponding wire 1 for transmitting AC signal in the second connector 50 through an AC signal wire 36-1 at the other end, and is electrically connected to the AC signal wire 28 at the port X1 of the adapter 20 through the wire 1 of the second connector 50, and is electrically connected to the first connector 40 at the port X1 of the adapter 20, and is electrically connected to the corresponding electrode sheet 10 at the first connector 40 at the port X1 of the adapter 20, so as to control whether the AC signal generator 34 delivers AC signal to the electrode sheet 10 electrically connected to the port X1 of the adapter 20; the second AC signal switch 35-2 is electrically connected to the AC signal generator 34 through the AC signal wire 36 of the electric field generator 30 at one end, and is electrically connected to the corresponding wire 2 for transmitting AC signal in the second connector 50 through an AC signal wire 36-2 at the other end, and is electrically connected to the AC signal wire 28 at the port Y1 of the adapter 20 through the wire 2 of the second connector 50, and is electrically connected to the first connector 40 at the port Y1 of the adapter 20, and is electrically connected to the corresponding electrode sheet 10 at the first connector 40 at the port Y1 of the adapter 20, so as to control whether the AC signal generator 34 delivers AC signal to the electrode sheet 10 electrically connected to the port Y1 of the adapter 20; the third AC signal switch 35-3 is electrically connected to the AC signal generator 34 through the AC signal wire 36 of the electric field generator 30 at one end, and is electrically connected to the corresponding wire 3 for transmitting AC signal in the second connector 50 through an AC signal wire 36-3 at the other end, and is electrically connected to the AC signal wire 28 at the port X2 of the adapter 20 through the wire 3 of the second connector 50, and is electrically connected to the first connector 40 at the port X2 of the adapter 20, and is electrically connected to the corresponding electrode sheet 10 at the first connector 40 at the port X2 of the adapter 20, so as to control whether the AC signal generator 34 delivers AC signal to the electrode sheet 10 electrically connected to the port X2 of the adapter 20; the fourth AC signal switch 35-4 is electrically connected to the AC signal generator 34 through the AC signal wire 36 of the electric field generator 30 at one end, and is electrically connected to the corresponding wire 4 for transmitting AC signal in the second connector 50 through an AC signal wire 36-4 at the other end, and is electrically connected to the AC signal wire 28 at the port Y2 of the adapter 20 through the wire 4 of the second connector 50, and is electrically connected to the first connector 40 at the port Y2 of the adapter 20, and is electrically connected to the corresponding electrode sheet 10 at the first connector 40 at the port Y2 of the adapter 20, so as to control whether the AC signal generator 34 delivers AC signal to the electrode sheet 10 electrically connected to the port Y1 of the adapter 20.

[0061] The following will be described with reference to Figures 6 to 14The working principle of the tumor electric field treatment device 100 of the embodiment is introduced in detail.

[0062] Specifically, when the temperature of each electrode unit 12 of a certain electrode sheet 10 needs to be detected, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls each of the 5 bidirectional switches 26 of the group of bidirectional switches 26 electrically connected to the electrode sheet 10 to be in the on state at the 1 end and in the off state at the 2 end, so as to disconnect the alternating current signal applied to the electrode sheet 10; at the same time, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls the first ground switch 25-1, the second ground switch 25-2, and the third ground switch 25-3 of each of the group of ground switches 25 electrically connected to the electrode sheet 10 to be sequentially and time-sharingly in the on state, at which time, the temperature detection signals collected by each temperature sensor 14 of each electrode unit 12 of each row group of the electrode sheet 10 can be sequentially and time-sharingly collected by each detection channel A, B, C, D, E of the group of analog-digital converters 23 corresponding to the electrode sheet 10. Each detection channel A, B, C, D, E of each group of analog-digital converters 23 only collects the temperature detection signal of the temperature sensor 14 of the corresponding electrode unit 12 of each electrode unit 12 in the same row group of the electrode sheet 10 at the same time, and the above-mentioned temperature detection signal can be represented by a voltage value. Only one ground switch 25 of the three ground switches 25 (the first ground switch 25-1, the second ground switch 25-2, and the third ground switch 25-3) of the group of ground switches 25 corresponding to the electrode sheet 10 can be in the on state at the same time, and the other two ground switches 25 are in the off state. The 5 bidirectional switches 26 of the group of bidirectional switches 26 corresponding to the group of analog-digital converters 23 are all switched to the 1 end to make each two-way signal line 19 of the electrode sheet 10 electrically connected to the corresponding detection channel A, B, C, D, E of the corresponding analog-digital converter 23 in a one-to-one correspondence, so that the group of analog-digital converters 23 can collect the voltage values of all temperature sensors 14 of each electrode unit 12 in the same row group short-circuited by the ground switch 25 corresponding to the on state.

[0063] Specifically, when the first grounding switch 25-1 is closed, the second grounding switch 25-2 and the third grounding switch 25-3 are both open, and the first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4 and the fifth bidirectional switch 26-5 are all switched to the 1 end, the temperature sensors 14 of the electrode units 12-1 to 12-5 in the first row group are powered on, the temperature sensors 14 of the electrode units 12-6 to 12-13 in the remaining row groups are powered off, the signal ends 14-2 of the temperature sensors 14 of the electrode units 12-1, 12-6 and 12-11 on the first detection channel A of the analog-to-digital converter 23 are short-circuited, only the ground end 14-1 of the temperature sensor 14 of the electrode unit 12-1 is connected to the ground, the ground ends 14-1 of the temperature sensors 14 of the electrode units 12-6 and 12-11 are both disconnected, and each electrode unit 12 is provided with a diode 16 connected in series with the temperature sensor 14, so the resistance of the temperature sensor 14 of the electrode unit 12-1 is not affected by the remaining temperature sensors 14 in the first row. Therefore, only the temperature sensor 14 of the electrode unit 12-1 on the first detection channel A of the analog-to-digital converter 23 works effectively, and the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 of the electrode unit 12-1. Similarly, the voltage value collected by the second detection channel B of the analog-to-digital converter 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-2. The voltage value collected by the third detection channel C of the analog-to-digital converter 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-3. The voltage value collected by the fourth detection channel D of the analog-to-digital converter 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-4. The voltage value collected by the fifth detection channel E of the analog-to-digital converter 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-5.

[0064] When the second grounding switch 25-2 is closed, the first grounding switch 25-1 and the third grounding switch 25-3 are both open, and the first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4 and the fifth bidirectional switch 26-5 are all switched to the 1 end, the temperature sensors 14 of the electrode units 12-6 to 12-10 of the second row group are powered on, the temperature sensors 14 of the electrode units 12-1 to 12-5 and 12-11 to 12-13 of the remaining row groups are powered off, the signal ends 14-2 of the temperature sensors 14 of the electrode units 12-1, 12-6 and 12-11 are short-circuited on the first detection channel A of the group of analog-to-digital converters 23, only the ground end 14-1 of the temperature sensor 14 of the electrode unit 12-6 is connected to the ground, the ground ends 14-1 of the temperature sensors 14 of the electrode units 12-1 and 12-11 are disconnected, and a diode 16 is connected in series with the temperature sensor 14 on each electrode unit 12, so the remaining temperature sensors 14 in the second row do not affect the resistance value of the temperature sensor 14 of the electrode unit 12-6, and only the temperature sensor 14 of the electrode unit 12-6 works effectively on the first detection channel A of the group of analog-to-digital converters 23, so the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 of the electrode unit 12-6. Similarly, the voltage value collected by the second detection channel B of the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-7. The voltage value collected by the third detection channel C of the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-8. The voltage value collected by the fourth detection channel D of the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-9. The voltage value collected by the fifth detection channel E of the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-10.

[0065] When the third grounding switch 25-3 is closed, the first grounding switch 25-1 and the second grounding switch 25-2 are both open, and the first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4 and the fifth bidirectional switch 26-5 are all switched to the 1 end, the temperature sensors 14 of the electrode units 12-11 to 12-13 of the third row group are powered on, and the temperature sensors 14 of the electrode units 12-1 to 12-10 of the remaining row groups are powered off. The signal ends 14-2 of the temperature sensors 14 of the electrode units 12-1, 12-6 and 12-11 are short-circuited on the first detection channel A of the group of analog-to-digital converters 23. Since only the ground end 14-1 of the temperature sensor 14 of the electrode unit 12-11 is connected to the ground, and the ground ends 14-1 of the temperature sensors 14 of the electrode units 12-1 and 12-6 are both disconnected, and each electrode unit 12 is provided with a diode 16 connected in series with the temperature sensor 14, the remaining temperature sensors 14 in the third row do not affect the resistance value of the temperature sensor 14 of the electrode unit 12-11. Therefore, only the temperature sensor 14 of the electrode unit 12-11 works effectively on the first detection channel A of the group of analog-to-digital converters 23. At this time, the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature sensor 14 of the electrode unit 12-11. Similarly, the voltage value collected by the second detection channel B of the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-12. The voltage value collected by the third detection channel C of the group of analog-to-digital converters 23 is the voltage value of the temperature sensor 14 of the electrode unit 12-13. No voltage value of the temperature sensor 14 is collected on the fourth detection channel D and the fifth detection channel E of the group of analog-to-digital converters 23.

[0066] In the present embodiment, the fourth grounding switch 25-4 is in an idle open state and does not need to be operated. In other embodiments of the electrode sheet, the electrode sheet can have more groups of rows, corresponding to more grounding lines 18 connected, and when the fourth grounding switch 25-4 is connected to a corresponding grounding line 18, the fourth grounding switch 25-4 can be turned on and all the bidirectional switches 26 can be switched to the 1 end of each corresponding bidirectional switch 26, and the voltage values of the temperature sensors 14 on each electrode unit 12 turned on by the fourth grounding switch 25-4 can be further detected. The first controller 22, the plurality of groups of analog-to-digital converters 23, and the plurality of groups of bidirectional switches 26 can automatically perform operations through pre-programmed program codes, for example, the first controller 22 first controls all the bidirectional switches 26 in the corresponding group of bidirectional switches 26 to be switched to the 1 end, so that the 1 end of the bidirectional switches 26 is all turned on, and the 2 end is all turned off, so that each dual-purpose signal line 19 of the corresponding electrode sheet 10 is electrically connected to the corresponding group of analog-to-digital converters 23, then the first grounding switch 25-1 in the corresponding group of grounding switches 25 is closed, and the second grounding switch 25-2, the third grounding switch 25-3, and the fourth grounding switch 25-4 in the group of grounding switches 25 are opened, during which each detection channel A, B, C, D, and E of the group of analog-to-digital converters 23 obtains the temperature detection signals of each temperature sensor 14 of each electrode unit 12 in the first group of rows in the corresponding electrode sheet 10 and converts them into digital signals and stores them in another storage. After a preset interval, the first controller 22 closes the second grounding switch 25-2 in the group of grounding switches 25, and opens the first grounding switch 25-1, the third grounding switch 25-3, and the fourth grounding switch 25-4 in the group of grounding switches 25, during which each detection channel A, B, C, D, and E of the group of analog-to-digital converters 23 obtains the temperature detection signals of each temperature sensor 14 of each electrode unit 12 in the second group of rows. In this way, each grounding switch 25 in the group of grounding switches 25 can be turned on individually to obtain the temperature detection signals of all the temperature sensors 14 in each group of rows in the electrode sheet 10. Similarly, the temperature detection signals of all the temperature sensors 14 on at least one pair of electrode sheets 10 can be obtained through such operations. In the present embodiment, the fourth grounding switch 25-4 is in an idle open state and does not need to be operated.

[0067] The tumor electric field treatment device 100 can realize real-time and comprehensive monitoring of the temperature of all electrode units 12 on the electrode sheet 10 without increasing the weight of the electrode sheet 10 and the core of the first cable 13 electrically connected to the electrode sheet 10, and then can judge whether the electrode sheet 10 is qualified according to the obtained temperature detection signal; or can judge whether the temperature sensor 14 of the electrode sheet 10 is faulty or abnormal according to the obtained temperature detection signal, and judge whether the electrode sheet 10 needs to be replaced based on the number of faulty or abnormal temperature sensors 14 obtained; or can identify the type of the electrode sheet according to the obtained temperature detection signal in the case that the electrode sheet is qualified; or can judge whether the electrode unit 12 of the electrode sheet 10 is over-temperature according to the obtained temperature detection signal in the case that the electrode sheet is qualified, and then control the alternating electric signal applied to the electrode sheet 10 or the corresponding column electrode unit 12 of the electrode sheet 10 to avoid the occurrence of patient body surface low-temperature scald when the tumor treatment is performed through the electrode sheet 10. In addition, the flexible circuit board 11 of the electrode sheet 10 of the present application is electrically connected to the signal end 14-2 of the dielectric element 15 and the temperature sensor 14 of the same electrode unit 12 through the same dual-purpose signal line 19, which not only realizes that the alternating current signal, the direct current signal for temperature signal acquisition and the acquired temperature detection signal can be transmitted through the dual-purpose signal line 19, but also greatly reduces the number of conductive traces (grounding line 18, dual-purpose signal line 19) arranged thereon, reduces the wiring difficulty of the flexible circuit board 11, simplifies the manufacturing process, and also reduces the weight of the flexible circuit board 11 and the manufacturing cost. The electrode sheet 10 of the present application can also realize switching between applying alternating current signal for tumor treatment and transmitting direct current signal for temperature acquisition and transmitting acquired temperature detection signal through the combination control of the grounding switch 25 electrically connected to the grounding line 18 and the bidirectional switch 26 electrically connected to the dual-purpose signal line 19.

[0068] When it is required to apply an alternating current signal to the patient through each electrode unit 12 of a certain electrode pad 10, the first controller 22 of the adapter 20 or the second controller 32 of the electric field generator 30 controls each ground switch 25 in the group of ground switches 25 corresponding to the electrode pad 10 to be all turned off, and controls each bidirectional switch 26 in the group of bidirectional switches 26 corresponding to the electrode pad 10 to be all switched to the 2 terminal, so that the 1 terminal of each bidirectional switch 26 is all turned off and the 2 terminal is all turned on, realizing that each two-way signal line 19 of the electrode pad 10 is electrically connected to the AC signal line 28 of the adapter 20 corresponding to the electrode pad 10, so as to transmit the alternating current signal to each electrode unit 12 of the electrode pad 10.When the temperature detection signal of the temperature sensor 14 of all electrode units 12 of the electrode sheet 10 detected is far below the preset temperature threshold value stored in the electric field generator 30 or the adapter 20, the electric field generator 30 controls the AC signal generator 34 through the second controller 32 to continue generating the alternating current signal with the increasing voltage or current amplitude or the unchanged voltage or current amplitude, and then transmits the alternating current signal to the corresponding pair of electrode sheets 10 through the corresponding AC signal line 28 of the adapter 20, so that the pair of electrode sheets 10 continues to apply the alternating current signal; when the temperature detection signal of the temperature sensor 14 of all electrode units 12 of the electrode sheet 10 detected is below but close to the preset temperature threshold value stored in the electric field generator 30 or the adapter 20, the electric field generator 30 can reduce the voltage or current of the alternating current signal generated by the AC signal generator 34 through the second controller 32, and then reduce the voltage or current of the alternating current signal applied to the pair of electrode sheets 10; when it is detected that the temperature detection signal of the temperature sensor 14 of an electrode unit 12 of a certain electrode sheet 10 is greater than the preset temperature threshold value, the electric field generator 30 controls the AC signal switch 35 electrically connected with the electrode sheet 10 to be turned off through the second controller 32, so as to stop applying the alternating current signal to the electrode sheet 10; or the second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 controls all the bidirectional switching switches 26 in the group of bidirectional switching switches 26 electrically connected with the electrode sheet 10 to switch from the 2 end to the 1 end, that is, controls all the 1 ends of the bidirectional switching switches 26 in the group of bidirectional switching switches 26 electrically connected with the electrode sheet 10 to be all turned on and all the 2 ends to be all turned off, so as to stop applying the alternating current signal to the electrode sheet 10; or, when it is detected that the temperature detection signal of the temperature sensor 14 of an electrode unit 12 of a certain electrode sheet 10 is greater than the preset temperature threshold value, the second controller 32 of the electric field generator 30 controls the AC signal switch electrically connected with the electrode sheet 10 to continue to be turned on, and the second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 controls a bidirectional switching switch 26 electrically connected with the electrode unit 12 of the electrode sheet 10 to switch from the 2 end to the 1 end, and the second controller 32 of the electric field generator 30 or the first controller 22 of the adapter 20 simultaneously controls the 2 ends of the remaining bidirectional switching switches 26 electrically connected with the electrode units 12 whose temperature detection signals do not exceed the preset temperature threshold value and the electrode units 12 whose temperature detection signals exceed the preset temperature threshold value and are in different columns of electrode units 12 to continue to be electrically connected, so as to stop applying the alternating current signal to all the electrode units 12 in the column of the electrode unit 12 whose temperature detection signal exceeds the preset temperature threshold value of the electrode sheet 10 and continue to apply the alternating current signal to the remaining columns of electrode units 12 whose temperature detection signals do not exceed the preset temperature threshold value of the electrode sheet 10. Thus, the alternating current signal application control method based on the temperature detection signal of the tumor electric field treatment device 100 is realized.

[0069] The ground switch 25 electrically connected with the multi-path ground line 18 of the electrode sheet 10 and the bidirectional switch 26 electrically connected with the multi-path dual-purpose signal line 19 of the electrode sheet 10 are both arranged in the adapter 20, but in other embodiments, the ground switch 25 electrically connected with the ground line 18 and the bidirectional switch 26 electrically connected with the dual-purpose signal line 19 can also be arranged on the electrode sheet 10 or in the electric field generator 30, which will not be described here. In addition, the A / D converter 23 arranged in the adapter 20 can also be arranged in the electric field generator 30 and directly controlled by the second controller 32.

[0070] The present application also provides other embodiments of the electrode sheet 10 and the adapter 20, which will be described below respectively. Figures 6

[0071] The circuit arrangement of the electrode unit 12 of the electrode sheet 10 in the first embodiment described above is three rows and five columns, in which two rows each have 5 electrode units 12 and the other row has 3 electrode units. The present application also provides other circuit arrangements of the electrode unit 12, which will be described below with reference to Figures 7 ​As shown, the electrode sheet 10A in the second embodiment arranges the 9 electrode units 12 of the flexible circuit board 11A in three rows and five columns in the circuit, in which two rows have 4 electrode units 12 and one row has 5 electrode units 12. The electrode sheet 10A includes 3 ground lines 18 and 5 dual-purpose signal lines 19, each of the ground lines 18 is used to ground the ground terminals 14-1 of the temperature sensors 14 of each electrode unit 12 in the same row group; each of the dual-purpose signal lines 19 is used to short the dielectric elements 15 and the signal terminals 14-2 of the temperature sensors 14 of each electrode unit 12 in each column group; for receiving temperature detection signals or transmitting alternating current signals. The 3 ground lines 18 of the electrode sheet 10A include a first ground line 18-1, a second ground line 18-2 and a third ground line 18-3, the first row group includes the electrode unit 12-1 to the electrode unit 12-4, the second row group includes the electrode unit 12-5 to the electrode unit 12-8, and the third row group includes the electrode unit 12-9 to the electrode unit 12-13. Specifically, the first ground line 18-1 is used to ground the electrode unit 12-1 to the electrode unit 12-4 in the first row group; the second ground line 18-2 is used to ground the electrode unit 12-5 to the electrode unit 12-8 in the second row group; and the third ground line 18-3 is used to ground the electrode unit 12-9 to the electrode unit 12-13 in the third row group. The 5 dual-purpose signal lines 19 of the electrode sheet 10A include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, a fourth dual-purpose signal line 19-4 and a fifth dual-purpose signal line 19-5. One end of the first dual-purpose signal line 19-1 is connected to the dielectric elements 15 and the signal terminals 14-2 of the temperature sensors 14 of the electrode unit 12-1, the electrode unit 12-5 and the electrode unit 12-9, respectively; one end of the second dual-purpose signal line 19-2 is connected to the dielectric elements 15 and the signal terminals 14-2 of the temperature sensors 14 of the electrode unit 12-2, the electrode unit 12-6 and the electrode unit 12-10, respectively; one end of the third dual-purpose signal line 19-3 is connected to the dielectric elements 15 and the signal terminals 14-2 of the temperature sensors 14 of the electrode unit 12-3, the electrode unit 12-7 and the electrode unit 12-11, respectively; one end of the fourth dual-purpose signal line 19-4 is connected to the dielectric elements 15 and the signal terminals 14-2 of the temperature sensors 14 of the electrode unit 12-4, the electrode unit 12-8 and the electrode unit 12-12, respectively; and one end of the fifth dual-purpose signal line 19-5 is connected to the dielectric element 15 and the signal terminal 14-2 of the temperature sensor 14 of the electrode unit 12-13.

[0072] Correspondingly, the first ground switch 25-1, the second ground switch 25-2 and the third ground switch 25-3 on the adapter 20 are respectively electrically connected with the first ground line 18-1, the second ground line 18-2 and the third ground line 18-3 one by one, and the fourth ground switch 25-4 is in an idle open state. The first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3, the fourth bidirectional switch 26-4 and the fifth bidirectional switch 26-5 on the adapter 20 are respectively electrically connected with the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3, the fourth dual-purpose signal line 19-4 and the fifth dual-purpose signal line 19-5 one by one.

[0073] The working mode of the tumor electric field treatment device formed by the electrode sheet 10A, the adapter 20 and the electric field generator 30 is the same as that of the tumor electric field treatment device 100. When the 2 end of all the bidirectional switches 26 is turned on and the 1 end is turned off, all the dual-purpose signal lines 19 are turned on with the AC signal line 28, and all the electrode units 12 are connected to the AC signal. When the 1 end of all the bidirectional switches 26 is turned on and the 2 end is turned off, the temperature detection signal of the temperature sensor 14 of each electrode unit 12 in each row group can be obtained in turn by sequentially turning on each ground switch 25. Among them, the ground switch 25 and / or the bidirectional switch 26 in the idle open state can not be operated.

[0074] Reference Figures 8As shown, the electrode sheet 10B in the third embodiment arranges 13 electrode units 12 of the flexible circuit board 11B in four rows and four columns in the circuit, in which three rows each have four electrode units 12, and one row has one electrode unit 12. The electrode sheet 10B includes four ground lines 18 and four dual-purpose signal lines 19. Each ground line 18 is used to ground the ground end 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group. Each dual-purpose signal line 19 is connected to the signal end 14-2 of each dielectric element 15 and each temperature sensor 14 in each column group for receiving a temperature detection signal or transmitting an alternating current signal. The four ground lines 18 of the electrode sheet 10B include a first ground line 18-1, a second ground line 18-2, a third ground line 18-3, and a fourth ground line 18-4. The first row group includes the electrode unit 12-1 to the electrode unit 12-4, the second row group includes the electrode unit 12-5 to the electrode unit 12-8, the third row group includes the electrode unit 12-9 to the electrode unit 12-12, and the fourth row group includes the electrode unit 12-13. Specifically, the first ground line 18-1 is used to ground the ground end 14-1 of the temperature sensor 14 of each of the four electrode units 12-1 to 12-4 in the first row group; the second ground line 18-2 is used to ground the ground end 14-1 of the temperature sensor 14 of each of the four electrode units 12-5 to 12-8 in the second row group; the third ground line 18-3 is used to ground the ground end 14-1 of the temperature sensor 14 of each of the four electrode units 12-9 to 12-12 in the third row group; and the fourth ground line 18-4 is used to ground the ground end 14-1 of the temperature sensor 14 of the electrode unit 12-13 in the fourth row group. The four dual-purpose signal lines 19 of the electrode sheet 10B include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, and a fourth dual-purpose signal line 19-4.One end of the first dual-purpose signal line 19-1 is connected to the signal end 14-2 of the temperature sensor 14 and the dielectric element 15 of each of the four electrode units 12-1, 12-5, 12-9 and 12-13, respectively; one end of the second dual-purpose signal line 19-2 is connected to the signal end 14-2 of the temperature sensor 14 and the dielectric element 15 of each of the three electrode units 12-2, 12-6 and 12-10, respectively; one end of the third dual-purpose signal line 19-3 is connected to the signal end 14-2 of the temperature sensor 14 and the dielectric element 15 of each of the three electrode units 12-3, 12-7 and 12-11, respectively; and one end of the fourth dual-purpose signal line 19-4 is connected to the signal end 14-2 of the temperature sensor 14 and the dielectric element 15 of each of the three electrode units 12-4, 12-8 and 12-12, respectively.

[0075] Correspondingly, the first ground switch 25-1, the second ground switch 25-2, the third ground switch 25-3 and the fourth ground switch 25-4 on the adapter 20 are electrically connected to the corresponding one of the first ground line 18-1, the second ground line 18-2, the third ground line 18-3 and the fourth ground line 18-4, respectively. The first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3 and the fourth bidirectional switch 26-4 on the adapter 20 are electrically connected to the corresponding one of the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3 and the fourth dual-purpose signal line 19-4, respectively. The fifth bidirectional switch 26-5 is in an idle open state.

[0076] The working mode of the tumor electric field treatment device formed by the electrode sheet 10B, the adapter 20 and the electric field generator 30 is the same as that of the tumor electric field treatment device 100. When the 2 end of each of the bidirectional switches 26 is turned on and the 1 end is turned off, all the dual-purpose signal lines 19 are turned on with the AC signal line 28, and all the electrode units 12 are connected to the AC signal. When the 1 end of each of the bidirectional switches 26 is turned on and the 2 end is turned off, the temperature detection signals of the temperature sensors 14 of each electrode unit 12 in each row group can be obtained in turn by sequentially turning on the ground switches 25. The ground switch 25 and / or the bidirectional switch 26 in the idle open state can not be operated.

[0077] Reference Figures 9 to 11As shown, the electrode sheet 10C in the fourth embodiment arranges 13 electrode units 12 of the flexible circuit board 11C in four rows and four columns in the circuit, in which three rows each have three electrode units 12, and the other row has four electrode units 12. The electrode sheet 10C includes four ground lines 18 and four dual-purpose signal lines 19. Each ground line 18 is used to ground the ground end 14-1 of the temperature sensor 14 of each electrode unit 12 in the same row group. Each dual-purpose signal line 19 is used to short the dielectric element 15 and the signal end 14-2 of the temperature sensor 14 of each electrode unit 12 in each column group, for receiving a temperature detection signal or transmitting an alternating current signal. The four ground lines 18 of the electrode sheet 10C include a first ground line 18-1, a second ground line 18-2, a third ground line 18-3, and a fourth ground line 18-4. The first row group includes the electrode unit 12-1 to the electrode unit 12-3, the second row group includes the electrode unit 12-4 to the electrode unit 12-6, the third row group includes the electrode unit 12-7 to the electrode unit 12-9, and the fourth row group includes the electrode unit 12-10 to the electrode unit 12-13. Specifically, the first ground line 18-1 is used to ground the ground end 14-1 of the temperature sensor 14 of each of the three electrode units 12-1 to 12-3 in the first row group. The second ground line 18-2 is used to ground the ground end 14-1 of the temperature sensor 14 of each of the three electrode units 12-4 to 12-6 in the second row group. The third ground line 18-3 is used to ground the ground end 14-1 of the temperature sensor 14 of each of the three electrode units 12-7 to 12-9 in the third row group. The fourth ground line 18-4 is used to ground the ground end 14-1 of the temperature sensor 14 of each of the four electrode units 12-10 to 12-13 in the fourth row group. The four dual-purpose signal lines 19 of the electrode sheet 10C include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3, and a fourth dual-purpose signal line 19-4.One end of the first dual-purpose signal line 19-1 is connected to the signal end 14-2 of the dielectric element 15 and the temperature sensor 14 of each of the four electrode units 12-1, 12-4, 12-7 and 12-10; one end of the second dual-purpose signal line 19-2 is connected to the signal end 14-2 of the dielectric element 15 and the temperature sensor 14 of each of the four electrode units 12-2, 12-5, 12-8 and 12-11; one end of the third dual-purpose signal line 19-3 is connected to the signal end 14-2 of the dielectric element 15 and the temperature sensor 14 of each of the four electrode units 12-3, 12-6, 12-9 and 12-12; and one end of the fourth dual-purpose signal line 19-4 is connected to the signal end 14-2 of the dielectric element 15 and the temperature sensor 14 of the electrode unit 12-13.

[0078] Correspondingly, the first ground switch 25-1, the second ground switch 25-2, the third ground switch 25-3 and the fourth ground switch 25-4 on the adapter 20 are electrically connected to the corresponding one of the first ground line 18-1, the second ground line 18-2, the third ground line 18-3 and the fourth ground line 18-4. The first bidirectional switch 26-1, the second bidirectional switch 26-2, the third bidirectional switch 26-3 and the fourth bidirectional switch 26-4 on the adapter 20 are electrically connected to the corresponding one of the first dual-purpose signal line 19-1, the second dual-purpose signal line 19-2, the third dual-purpose signal line 19-3 and the fourth dual-purpose signal line 19-4, and the fifth bidirectional switch 26-5 is in an idle open state.

[0079] The working mode of the tumor electric field treatment device formed by the electrode sheet 10C, the adapter 20 and the electric field generator 30 is the same as that of the tumor electric field treatment device 100. When the 2 end of each of the bidirectional switches 26 is turned on and the 1 end is turned off, all the dual-purpose signal lines 19 are turned on with the AC signal line 28, and all the electrode units 12 are connected to the AC signal. When the 1 end of each of the bidirectional switches 26 is turned on and the 2 end is turned off, the temperature detection signals of the temperature sensors 14 of each of the electrode units 12 in each row group can be obtained in turn by turning on the ground switches 25 in turn. The ground switches 25 and / or the bidirectional switches 26 in the idle open state can not be operated.

[0080] It can be understood that in other embodiments, the number of ground switches 25 of the adapter 20 can be correspondingly arranged according to the number of ground wires 18 of the corresponding electrode sheet 10, 10A, 10B, 10C, and the number of bidirectional switches 26 can be correspondingly arranged according to the number of dual-purpose signal wires 19 of the corresponding electrode sheet 10, 10A, 10B, 10C, so as to avoid the idle and disconnected ground switches 25 and bidirectional switches 26.

[0081] Reference Figures 12 to 14 As shown in the figure, the tumor electric field treatment device in the embodiment can use the electrode sheet 10 or 10A in the first or second embodiment, and the electrode sheet 10 in the first embodiment and the electrode sheet 10A in the second embodiment are each provided with 3 ground wires 18 (first ground wire 18-1, second ground wire 18-2, and third ground wire 18-3) and 5 dual-purpose signal wires (first dual-purpose signal wire 19-1, second dual-purpose signal wire 19-2, third dual-purpose signal wire 19-3, fourth dual-purpose signal wire 19-4, and fifth dual-purpose signal wire 19-5). The adapter 20A used in the tumor electric field treatment device in the embodiment is a transformed embodiment of the adapter 20, that is, the second embodiment of the adapter 20; the adapter 20A is correspondingly provided with 3 ground switches 25 (first ground switch 25-1, second ground switch 25-2, and third ground switch 25-3) and 5 bidirectional switches 26 (first bidirectional switch 26-1, second bidirectional switch 26-2, third bidirectional switch 26-3, fourth bidirectional switch 26-4, and fifth bidirectional switch 26-5), and each group of analog-to-digital converter 23 includes five detection channels A, B, C, D, and E. In the embodiment, the first connector 40A formed between the electrode sheet 10 or 10A and the adapter 20A electrically connects the 3 ground switches 25 and the 3 ground wires 18 of the electrode sheet 10 or 10A one by one, respectively, and electrically connects the 5 bidirectional switches 26 and the 5 dual-purpose signal wires 19 of the electrode sheet 10 or 10A. The working mode of the tumor electric field treatment device formed by the electrode sheet 10 or 10A, the adapter 20A, and the electric field generator 30 is the same as that of the tumor electric field treatment device 100 described above, and will not be described again.

[0082] Reference ​As shown, the tumor electric field treatment device of the present embodiment can adopt the electrode sheet 10B in the third embodiment or the electrode sheet 10C in the fourth embodiment, and the electrode sheet 10B in the third embodiment and the electrode sheet 10C in the fourth embodiment are each provided with 4 ground lines 18 (first ground line 18-1, second ground line 18-2, third ground line 18-3, fourth ground line 18-4) and 4 dual-purpose signal lines (first dual-purpose signal line 19-1, second dual-purpose signal line 19-2, third dual-purpose signal line 19-3, fourth dual-purpose signal line 19-4), and the adapter 20B adopted by the tumor electric field treatment device of the present embodiment is another variant of the aforementioned adapter 20; the adapter 20B in the present embodiment is correspondingly provided with 4 ground switches 25 (first ground switch 25-1, second ground switch 25-2, third ground switch 25-3, fourth ground switch 25-4) and 4 bidirectional switches 26 (first bidirectional switch 26-1, second bidirectional switch 26-2, third bidirectional switch 26-3, fourth bidirectional switch 26-4), and each group of analog-to-digital converters 23 correspondingly includes four detection channels A, B, C, and D. In the present embodiment, the connector 40B formed between the electrode sheet 10B or the electrode sheet 10C and the adapter 20B electrically connects the 4 ground switches 25 and the 4 ground lines 18 of the electrode sheet 10B or 10C in one-to-one correspondence, respectively, and electrically connects the 4 bidirectional switches 26 and the 4 dual-purpose signal lines 19 of the electrode sheet 10B or 10C in one-to-one correspondence, respectively. The working mode of the tumor electric field treatment device formed by the electrode sheet 10B or 10C, the adapter 20B, and the electric field generator 30 is the same as that of the tumor electric field treatment device 100 described above, and will not be described again.

[0083] Finally, it should be noted that: the above embodiments are only used to illustrate the technical solutions of the present application, and not to limit them; although the present application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that: it can still modify the technical solutions recorded in the foregoing embodiments, or make equivalent replacement to part or all of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the present application, and they should be covered in the scope of the claims and the description of the present application. Especially, as long as there is no structural conflict, each technical feature mentioned in each embodiment can be combined in any way. The present application is not limited to the specific embodiments disclosed herein, but includes all technical solutions falling within the scope of the claims.

Claims

1. An electrode sheet, characterized by, The electrode sheet comprises: a plurality of electrode units, the plurality of electrode units being divided into a plurality of row groups and a plurality of column groups in circuit connection; the number of row groups of the electrode units is 3, and the number of column groups of the electrode units is 5 or the number of row groups and the number of column groups of the electrode units are both 4, and a flexible circuit board configured to have the plurality of electrode units arranged thereon at intervals, and having a plurality of conductive tracks embedded therein, the plurality of conductive tracks comprising: a plurality of ground lines, each of the ground lines being electrically connected to each of the row groups of the electrode units in a one-to-one correspondence, and each of the ground lines being configured to short the corresponding parts of each of the electrode units in the corresponding row group to ground, and a plurality of dual-purpose signal lines, each of the dual-purpose signal lines being electrically connected to each of the column groups of the electrode units in a one-to-one correspondence, and each of the dual-purpose signal lines being configured to transmit alternating current signals to each of the electrode units in the corresponding column group and to transmit direct current signals or temperature detection signals detected by each of the electrode units in the corresponding column group.

2. The electrode pad of claim 1, wherein The number of the dual-purpose signal lines is equal to the number of the column groups in which the electrode units are divided, and / or the number of the ground lines is equal to the number of the row groups in which the electrode units are divided.

3. The electrode pad of claim 2, wherein The flexible circuit board is provided with a plurality of connecting portions, the number of the electrode units is 13, and the electrode units are arranged in 5 rows in structure, 2 electrode units are arranged in each of the first and last rows, and 3 electrode units are arranged in each of the middle three rows, a space is formed between the 2 electrode units arranged in the first or last row, and / or a space is formed between some of the electrode units arranged in the middle three rows and the adjacent electrode units.

4. The electrode sheet according to any one of claims 1 to 3, characterized by, Each of the electrode units comprises a dielectric element for transmitting alternating current signals and a temperature sensor for detecting the temperature of the corresponding electrode unit and having a signal terminal and a ground terminal, and the dielectric element of each of the electrode units is shorted to the signal terminal of the temperature sensor.

5. The electrode pad of claim 1, wherein Only one of the plurality of ground lines is turned on at the same time when the electrode units perform temperature detection, and the remaining plurality of ground lines are turned off, and all of the plurality of dual-purpose signal lines are turned on when the electrode units perform temperature detection; or all of the plurality of dual-purpose signal lines are turned on or part of the plurality of dual-purpose signal lines are turned on when the electrode units apply alternating current signals, and all of the plurality of ground lines are turned off when the electrode units apply alternating current signals.

6. A tumor electric field treatment device, characterized by, The electrode sheet comprises at least one pair of electrode sheets as claimed in any one of claims 1-5.

7. The tumor electric field treatment device of claim 6, wherein, Further comprising: an electric field generator configured to provide alternating current signals to the plurality of electrode units of the electrode sheet via the dual-purpose signal lines of the electrode sheet; and an adapter connected between the electrode sheet and the electric field generator, configured to deliver the alternating current signals generated by the electric field generator to the plurality of dual-purpose signal lines of the electrode sheet, and further configured to receive the temperature detection signals output by the plurality of dual-purpose signal lines of the electrode sheet, the adapter comprising: an AC signal line configured to provide alternating current signals to each of the electrode units in the corresponding column group through the plurality of dual-purpose signal lines.

8. The tumor electric field treatment device of claim 7, wherein, The adapter further comprises: a plurality of groups of grounding switches, each group of grounding switches being electrically connected to a corresponding electrode sheet and including a plurality of grounding switches, the plurality of grounding switches being respectively electrically connected to the plurality of ground lines of the corresponding electrode sheet and configured to control the plurality of ground lines to be turned on or turned off.

9. The tumor electric field treatment device of claim 8, wherein, The adapter further includes: a plurality of groups of analog-digital converters, respectively electrically connected to the plurality of two-purpose signal lines of the corresponding electrode sheet and configured to receive the temperature detection signals transmitted by the plurality of two-purpose signal lines of the corresponding electrode sheet and convert the temperature detection signals from analog signals to digital signals, wherein each group of the analog-digital converters includes a plurality of detection channels, each detection channel being used to connect a corresponding two-purpose signal line of the plurality of two-purpose signal lines; and a plurality of groups of bidirectional switching switches, respectively corresponding to the plurality of electrode sheets, each group of bidirectional switching switches including a plurality of bidirectional switching switches, the plurality of bidirectional switching switches being respectively electrically connected to the plurality of two-purpose signal lines of the corresponding electrode sheet, wherein each bidirectional switching switch further has a 1 terminal electrically connected to a corresponding detection channel of the corresponding analog-digital converter and a 2 terminal electrically connected to the AC signal line.

10. The tumor electric field treatment device of claim 9, wherein, The adapter further includes: a first controller connected to the plurality of groups of grounding switches and the plurality of groups of bidirectional switching switches and configured to: sequentially and cyclically control the on-off states of the plurality of grounding switches, thereby sequentially and individually turning on each ground line of the plurality of ground lines of the corresponding electrode sheet; and control the switching states of the plurality of bidirectional switching switches, so that the bidirectional switching switch is placed at the 1 terminal to output the temperature detection signal or the bidirectional switching switch is placed at the 2 terminal to transmit the AC signal.

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