Equivalent mixing device for protein detection

Abstract

The utility model discloses an equivalent mixing device for protein detection, which comprises a base, a first support, a water bath and a mixing pipe, and the water bath and the first support are both arranged on the base; a fixing ring is detachably arranged on the side surface of the uniform mixing pipe; the device further comprises a uniform shaking assembly and a driving assembly. The uniform shaking assembly comprises a first placing plate and a second placing plate, and the first placing plate is connected with the first bracket through a second bracket; the first placing plate is arranged below the second placing plate, and the first placing plate is connected with the second placing plate through a first spring; a plurality of placing grooves are formed in the second placing plate, and the placing grooves are matched with the fixing rings; the driving assembly comprises a connecting block, and the second containing plate is connected with the connecting block. According to the utility model, the driving assembly pushes the second placing plate to move relative to the first placing plate through the connecting block, so that reagents in the mixing tubes in the placing groove can be uniformly mixed, and the plurality of mixing tubes can be synchronously and uniformly mixed while heating is realized.

Description

Technical Field

[0001] This invention belongs to the field of protein detection technology, and in particular relates to an equal-volume mixing device for protein detection. Background Technology

[0002] Proteins are organic macromolecules, the basic organic components of cells, the main carriers of life activities, and important components of organisms. Proteins are substances closely linked to life and all forms of life activities; every cell and all vital components of the body involve proteins, which play key roles in many biological processes. Protein detection is an important analytical technique in biochemical and molecular biological research.

[0003] Common methods for detecting protein content include the Kjeldahl method and the biuret method. These methods all require mixing various reagents in test tubes. In current technology, when mixing equal amounts of cellular proteins, the mixing bottle is usually held by hand, and multiple test tubes are needed during the detection process. After the reagents in each test tube are prepared, the staff must manually shake them to mix them. This operation is laborious and cumbersome, and the manual shaking method results in a lower degree of reagent uniformity, which can affect the protein detection results to some extent. Utility Model Content

[0004] Based on the above background, the purpose of this utility model is to provide an equal volume mixing device for protein detection.

[0005] To achieve the above objectives, the present invention adopts the following technical solution:

[0006] An equal-volume mixing device for protein detection includes a base, a first support, a water bath, and a mixing tube, wherein the water bath and the first support are both disposed on the base.

[0007] The mixing tube is detachably provided with a retaining ring on its side;

[0008] It also includes a shaking component and a driving component;

[0009] The shaking assembly includes a first placement plate and a second placement plate, wherein the first placement plate is connected to the first support via a second bracket.

[0010] The first placement plate is located below the second placement plate, and the first placement plate is connected to the second placement plate by a first spring;

[0011] The second placement plate has multiple placement slots, which are adapted to the fixing ring;

[0012] The driving component includes a connecting block, and the second placement plate is connected to the connecting block. The plate shakes under the action of the driving component to mix the mixing tube.

[0013] Through the above technical solution, the driving component pushes the second placement plate to move relative to the first placement plate through the connecting block, which can mix the reagent in the mixing tube in the placement tank, and realize the synchronous and uniform mixing of multiple mixing tubes while heating.

[0014] Preferably, the drive assembly further includes a mounting box and a motor; both the mounting box and the motor are mounted on the second bracket.

[0015] The mounting box is equipped with an active drive block and an auxiliary drive block. The active drive block is rotatably connected to the mounting box, and the auxiliary drive block extends out of the mounting box at both ends and is slidably connected to the mounting box.

[0016] The output end of the motor extends into the mounting box and is connected to the active drive block;

[0017] The active drive block has a drive groove on its side, and a movable block is slidably disposed in the drive groove. The movable block is fixedly connected to the auxiliary drive block.

[0018] The auxiliary drive block is slidably connected to the connecting block via a slider.

[0019] With the above technical solution, when the motor drives the active drive block to rotate, the auxiliary drive block moves left and right by sliding the moving block in the drive groove, thereby driving the second placement plate to move left and right relative to the first placement plate, and mixing the mixing tube.

[0020] Preferably, the connecting block is provided with a sliding groove and a rotating groove;

[0021] The slider is slidably disposed in the sliding groove;

[0022] The active drive block extends from the mounting box at one end away from the motor and is eccentrically connected to a rotating ring. The rotating ring is located in a rotating groove and its side is in contact with one side of the rotating groove.

[0023] Through the above technical solution, when the rotating ring rotates with the active drive block, it generates a thrust on one side of the rotating groove, thereby pushing the connecting block to drive the second placement plate to shake back and forth, improving the shaking efficiency of the mixing tube.

[0024] Preferably, the auxiliary drive block includes a cylindrical block and a square block, and the side length of the square block is larger than the diameter of the cylindrical block. A second spring is sleeved on the cylindrical block, and the two ends of the second spring are respectively connected to the mounting box and the square block, which plays a buffering role in the movement of the auxiliary drive block.

[0025] Preferably, the first placement plate has a through groove, and the through groove has a protective layer. The protective layer can be a damping material, foam, silicone, or other support to prevent the bottom of the mixing tube from being bumped during the mixing process.

[0026] Preferably, a limiting groove is formed on the second placement plate, and the limiting groove is coaxially arranged with the placement groove;

[0027] The top of the fixed ring is provided with a limiting ring, which is engaged with the limiting groove.

[0028] The retaining ring is made of elastic materials such as silicone and rubber, which can accommodate mixing tubes of different diameters.

[0029] Preferably, the limiting groove is provided with a positioning groove, the limiting ring is provided with a positioning block, and the positioning block is inserted into the positioning groove.

[0030] The above technical solution can better fix the mixing tube.

[0031] This utility model has the following beneficial effects:

[0032] 1. This utility model uses a driving mechanism to move the second placement plate relative to the first placement plate, which can mix the reagents in the mixing tubes in the placement tank, achieving simultaneous and uniform mixing of multiple mixing tubes while heating.

[0033] 2. This utility model uses a sliding block in the drive groove to enable the auxiliary drive block to push the second placement plate to move left and right. When the rotating ring rotates with the active drive block, it generates a thrust on one side of the rotating groove, thereby pushing the connecting block to make the second placement plate sway back and forth, realizing the back-and-forth and left-and-right swaying of the mixing tube and improving the mixing degree. Attached Figure Description

[0034] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on the structures shown in these drawings without creative effort.

[0035] Figure 1 This is a three-dimensional structural diagram of the present invention;

[0036] Figure 2 This is a three-dimensional structural diagram of the shaking and driving components of this utility model.

[0037] Figure 3 For the present utility model Figure 2 A magnified structural diagram at point A;

[0038] Figure 4 This is a three-dimensional structural diagram of the fixing ring of this utility model;

[0039] Figure 5 This is a three-dimensional structural diagram of the connecting block of this utility model;

[0040] Figure 6 This is a three-dimensional structural diagram of the disassembled drive component of this utility model.

[0041] Wherein: 1. Base; 11. First support; 12. Second support;

[0042] 2. Water bath tank;

[0043] 3. Mixing tube; 31. Fixing ring; 32. Limiting ring; 33. Limiting groove; 34. Positioning groove; 35. Positioning block;

[0044] 4. Shaking assembly; 41. First placement plate; 42. Second placement plate; 43. First spring; 44. Placement slot; 45. Through slot; 46. Protective layer;

[0045] 5. Drive assembly; 51. Connecting block; 52. Mounting box; 53. Motor; 54. Active drive block; 55. Auxiliary drive block; 56. Rotating ring; 57. Drive groove; 58. Moving block; 59. Slider; 510. Rotating groove; 511. Sliding groove; 512. Second spring. Detailed Implementation

[0046] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0047] It should be noted that all directional indicators (such as up, down, left, right, front, back, etc.) in this utility model embodiment are only used to explain the relative positional relationship and movement of each component in a certain specific posture (as shown in the figure). If the specific posture changes, the directional indicator will also change accordingly.

[0048] Furthermore, in this utility model, descriptions involving "first," "second," etc., are for descriptive purposes only and should not be construed as indicating or implying their relative importance or implicitly specifying the number of technical features indicated. Therefore, a feature defined with "first" or "second" may explicitly or implicitly include at least one of that feature. Additionally, the technical solutions of the various embodiments can be combined with each other, but only on the basis of being achievable by those skilled in the art. When the combination of technical solutions is contradictory or impossible to implement, such a combination of technical solutions should be considered non-existent and not within the scope of protection claimed by this utility model.

[0049] like Figure 1-6 As shown, an equal volume mixing device for protein detection includes a base 1, a first support 11, a water bath 2, a mixing tube 3, a shaking assembly 4, and a driving assembly 5. The water bath 2 and the first support 11 are both mounted on the base 1. The water bath 2 is a prior art device containing water or other solutions and has a heating function.

[0050] The mixing tube 3 has a detachable fixing ring 31 on its side. The fixing ring 31 is made of elastic materials such as silicone and rubber. It can be put on the side of the mixing tube 3 from the top or bottom and can be adapted to mixing tubes 3 of different diameters.

[0051] The shaking assembly 4 includes a first placement plate 41 and a second placement plate 42. The first placement plate 41 is connected to the first support 11 via a second support 12. The second support 12 can be moved up and down on the side of the first support 11 by an external power source such as a cylinder (not shown in the figure). When the equipment is not in use, the shaking assembly 4 can be moved to the top of the water bath tank 2.

[0052] The first placement plate 41 is located below the second placement plate 42, and the first placement plate 41 is connected to the second placement plate 42 by a first spring 43. Multiple first springs 43 are provided and are evenly distributed between the first placement plate 41 and the second placement plate 42.

[0053] The second placement plate 42 has multiple placement slots 44, which are adapted to the fixing ring 31. After the fixing ring 31 is put onto the mixing tube 3, it is placed on the placement slot 44. The movement of the second placement plate 42 shakes the mixing tube 3.

[0054] A through groove 45 is provided on the first placement plate 41. For the mixing tube 3 whose height is higher than the distance between the first placement plate 41 and the second placement plate 42, the lower end of the mixing tube 3 can pass through the first placement plate 41 through the through groove 45. A protective layer 46 is provided in the through groove 45. The protective layer 46 can be a damping material, foam, silicone, or other support to prevent the bottom of the mixing tube 3 from being hit during the mixing process.

[0055] The connecting block 51 of the drive component 5 is connected to the second placement plate 42. The drive component 5 can push the second placement plate 42 back and forth and left and right on the horizontal plane, thereby shaking the mixing tube 3.

[0056] After the water bath 2 is heated to the required temperature, the fixing ring 31 is placed from the bottom or top onto the upper side of the mixing tube 3, and the mixing tube 3 is placed into the placement groove 44. The fixing ring 31 is engaged with the placement groove 44 to fix the mixing tube 3. After all the mixing tubes 3 that need to be mixed are placed, the mixing tubes 3 are located in the water bath 2. The second placement plate 42 is pushed back and forth by the drive component 5. The second placement plate 42 shakes back and forth relative to the first placement plate 41, thereby realizing the simultaneous shaking and mixing of multiple mixing tubes 3 with the same force, improving the mixing efficiency.

[0057] The drive assembly 5 includes a mounting box 52 and a motor 53. The mounting box 52 and the motor 53 are mounted on the second bracket 12. The mounting box 52 contains an active drive block 54 and an auxiliary drive block 55. The active drive block 54 is rotatably connected to the mounting box 52. The output end of the motor 53 extends into the mounting box 52 and is connected to the active drive block 54. The active drive block 54 has a drive groove 57 on its side. A moving block 58 is slidably mounted in the drive groove 57. The moving block 58 is fixedly connected to the auxiliary drive block 55. The auxiliary drive block 55 includes a cylindrical block and a square block. The side length of the square block is larger than the diameter of the cylindrical block. A second spring 512 is sleeved on the cylindrical block. The two ends of the second spring 512 are respectively connected to the mounting box 52 and the square block. Because the drive groove 57 is arranged around the side of the active drive block 54 and is a closed loop, when the active drive block 54 rotates, the moving block 58 slides in the drive groove 57 and moves along the axis of the active drive block 54 along the path of the drive groove 57, thereby driving the auxiliary drive block 55 to move.

[0058] The connecting block 51 is provided with a sliding groove 511 and a rotating groove 510. One end of the auxiliary drive block 55 is provided with a slider 59, which slides in the sliding groove 511. The end of the active drive block 54 away from the motor 53 extends out of the mounting box 52 and is eccentrically connected to a rotating ring 56. The rotating ring 56 is located in the rotating groove 510 and its side is in contact with one side of the rotating groove 510. The active drive ring 54 drives the rotating ring 56 to rotate. Because the rotating ring 56 is eccentrically set, when the end of the rotating ring 56 away from the rotation axis rotates to contact the side of the rotating groove 510, it will push the connecting block 51 to move the second placement plate 42 back and forth. At the same time, the slider 59 slides back and forth in the sliding groove 511 and will not interfere with the thrust of the auxiliary drive block 55 on the connecting block 51. The two ends of the rotating ring 56 pass through and extend out of the two ends of the rotating groove 510. While the connecting block 51 moves left and right, the rotating ring 56 will not detach from the rotating groove 510.

[0059] The second placement plate 42 has a limiting groove 33, and a positioning groove 34 is provided on the limiting groove 33. The limiting groove 33 and the placement groove 44 are coaxially arranged. The top of the fixing ring 31 has a limiting ring 32, and a positioning block 35 is provided on the limiting ring 32. The limiting ring 32 is snapped into the limiting groove 33, and the positioning block 35 is inserted into the positioning groove 34. When the mixing tube 3 is placed in the placement groove 44, the positioning block 35 is inserted into the positioning groove 34, and the limiting block 32 is connected to the limiting groove 33, which can better fix the mixing tube 3.

[0060] The working principle of this utility model is as follows: After the water bath 2 is heated to the required temperature, the fixing ring 31 is placed from the bottom or top onto the upper side of the mixing tube 3, and the mixing tube 3 is placed into the placement groove 44. The fixing ring 31 is engaged with the placement groove 44, the positioning block 35 is inserted into the positioning groove 34, and the limiting block 32 is connected to the limiting groove 33, which can better fix the mixing tube 3. After all the mixing tubes 3 to be mixed are placed, the mixing tubes 3 are located in the water bath 2. The motor 53 is started, which drives the active drive ring 54 to rotate. The active drive ring 54 drives the rotating ring 56 to rotate. With the eccentric setting, when the end of the rotating ring 56 away from the rotation axis rotates to contact the side of the rotating groove 510, it will push the connecting block 51 to drive the second placement plate 42 to move back and forth. At the same time, the moving block 58 slides in the driving groove 57 and moves along the axis of the active driving block 54 along the path of the driving groove 57, thereby driving the auxiliary driving block 55 to move the connecting block 51 and the second placement plate 42 left and right. Meanwhile, the slider 59 slides back and forth in the sliding groove 511, without interfering with the thrust of the auxiliary driving block 55 on the connecting block 51. This can realize the synchronous shaking of multiple mixing tubes 3 and improve the mixing efficiency.

[0061] Of course, the above description is not intended to limit the present utility model, and the present utility model is not limited to the examples given above. Any changes, modifications, additions or substitutions made by those skilled in the art within the scope of the present utility model should also fall within the protection scope of the present utility model.

Claims

1. A mixing device for protein detection, comprising a base (1), a first support (11), a water bath (2), and a mixing tube (3), characterized in that: The water bath (2) and the first bracket (11) are both mounted on the base (1); The mixing tube (3) is detachably provided with a fixing ring (31) on its side; It also includes a shaking component (4) and a driving component (5); The shaking assembly (4) includes a first placement plate (41) and a second placement plate (42), wherein the first placement plate (41) is connected to the first support (11) via a second support (12); The first placement plate (41) is located below the second placement plate (42), and the first placement plate (41) is connected to the second placement plate (42) by a first spring (43); The second placement plate (42) is provided with a plurality of placement slots (44), which are adapted to the fixing ring (31); The driving component (5) includes a connecting block (51), the second placement plate (42) is connected to the connecting block (51), and the driving component (5) mixes the mixing tube (3).

2. The equal-volume mixing device for protein detection according to claim 1, characterized in that: The drive assembly (5) also includes a mounting box (52) and a motor (53); both the mounting box (52) and the motor (53) are mounted on the second bracket (12); The mounting box (52) is provided with an active drive block (54) and an auxiliary drive block (55). The active drive block (54) is rotatably connected to the mounting box (52), and the auxiliary drive block (55) extends out of the mounting box (52) at both ends and is slidably connected to the mounting box (52). The output end of the motor (53) extends into the mounting box (52) and is connected to the active drive block (54); The active drive block (54) has a drive groove (57) on its side, and a moving block (58) is slidably disposed in the drive groove (57). The moving block (58) is fixedly connected to the auxiliary drive block (55). The auxiliary drive block (55) is slidably connected to the connecting block (51) via a slider (59).

3. The equal-volume mixing device for protein detection according to claim 2, characterized in that: The connecting block (51) is provided with a sliding groove (511) and a rotating groove (510); The slider (59) is slidably disposed in the sliding groove (511); The active drive block (54) extends out of the mounting box (52) at the end away from the motor (53) and is eccentrically connected to a rotating ring (56). The rotating ring (56) is located in the rotating groove (510) and the side of the rotating ring (56) is in contact with one side of the rotating groove (510).

4. The equal-volume mixing device for protein detection according to claim 2, characterized in that: The auxiliary drive block (55) includes a cylindrical block and a square block, and the side length of the square block is larger than the diameter of the cylindrical block. A second spring (512) is sleeved on the cylindrical block, and the two ends of the second spring (512) are respectively connected to the mounting box (52) and the square block.

5. The equal-volume mixing device for protein detection according to claim 1, characterized in that: The first placement plate (41) has a through groove (45) and a protective layer (46) is provided inside the through groove (45).

6. The equal-volume mixing apparatus for protein detection according to any one of claims 1-5, characterized in that: A limiting groove (33) is provided on the second placement plate (42), and the limiting groove (33) is coaxially arranged with the placement groove (44); The top of the fixed ring (31) is provided with a limiting ring (32), and the limiting ring (32) is snapped into the limiting groove (33).

7. The equal-volume mixing device for protein detection according to claim 6, characterized in that: The limiting groove (33) is provided with a positioning groove (34), and the limiting ring (32) is provided with a positioning block (35). The positioning block (35) is inserted into the positioning groove (34).

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