Penicillin sodium production equipment for continuous fluid separation

Abstract

The utility model relates to the technical field of penicillin sodium production equipment, in particular to penicillin sodium production equipment for continuous fluid separation, which comprises a bottom plate, a support rod is fixedly mounted at the middle end of the top of the bottom plate, and a double-head motor is fixedly mounted at the middle end of an inner cavity of the support rod. The two output ends of the double-end motor are fixedly connected with threaded rods, the outer surfaces of the threaded rods are in threaded connection with movable sleeves, and the outer surfaces of the movable sleeves are fixedly connected with movable rings. Through the cooperation of the structures, the production equipment has the advantage that the resin in the resin barrel does not need to be replaced by frequently disassembling and assembling the heating equipment, and solves the problem that the existing traditional heating equipment fixed on the outer side of the strong acid type cation exchange resin barrel cannot be replaced; when the adsorption capacity of resin in the strong acid type cation exchange resin cylinder is reduced and the resin needs to be replaced, heating equipment on the outer side of the strong acid type cation exchange resin cylinder needs to be frequently disassembled and assembled, and the operation process is very tedious and labor-consuming.

Description

TECHNICAL FIELD

[0001] The utility model relates to penicillin sodium production equipment technical field, specifically is a continuous fluid separation's penicillin sodium production equipment. BACKGROUND

[0002] Penicillin sodium, trade name penicillin G sodium, benzyl penicillin sodium salt, benzyl penicillin sodium, white crystalline powder. Decomposition point is 215 DEG C, specific optical rotation [alpha] D 24.8+301 DEG (2% aqueous solution). Very soluble in water, dissolve in ethanol, insoluble in fatty oil liquid paraffin. Hygroscopic, meet acid, alkali, oxidizing agent, penicillin enzyme etc. can make penicillin's beta-lactam ring open and lose effectiveness. Crystalline penicillin sodium salt property is stable, its aqueous solution is easy to lose effectiveness at room temperature, can not be boiled to disinfect. Odorless or slightly have specificity smell. Penicillin G's antibiotic value is expressed in international unit (U), and an international unit is equal to 0.6ug of pure crystalline penicillin sodium salt's antibacterial activity. Penicillin has strong antibacterial effect, high curative effect and low toxicity and the like, so it is still widely used. Penicillin is organic acid, can be combined with a variety of metal into salt, commonly used its sodium salt or potassium salt. Penicillin can be removed acyl by chemical cleavage and generate 6-APA (6-amino penicillanic acid), is the intermediate of various semi-synthetic penicillin.

[0003] At present, the production of penicillin sodium needs to use continuous fluid separation's penicillin sodium production equipment, when the fluid enters the product conversion zone in the continuous fluid separation's penicillin sodium production equipment in the use process, heating is an important step, mainly used for solvent extraction and crystallization process, in the solvent extraction process, heating can help to improve extraction efficiency, make penicillin sodium more easily separate from fermentation broth, but the existing traditional heating equipment fixed outside the strong acid type cation exchange resin cylinder, when the resin in the strong acid type cation exchange resin cylinder needs to be replaced in adsorption capacity decline, the heating equipment outside the strong acid type cation exchange resin cylinder needs to be frequently disassembled, its operation process is very tedious and laborious, for this purpose, we propose a continuous fluid separation's penicillin sodium production equipment. UTILITY MODEL CONTENTS

[0004] The utility model aims at providing a kind of continuous fluid separation's penicillin sodium production equipment, with the advantage of not needing frequently disassembled heating equipment to replace resin in resin cylinder, solve the existing traditional heating equipment fixed outside the strong acid type cation exchange resin cylinder, when the resin in the strong acid type cation exchange resin cylinder needs to be replaced in adsorption capacity decline, the heating equipment outside the strong acid type cation exchange resin cylinder needs to be frequently disassembled, its operation process is very tedious and laborious Problem.

[0005] In order to achieve the above object, the utility model provides the following technical scheme: a continuous fluid separation penicillin sodium production equipment, including the bottom plate, the middle end fixed mounting of bottom plate top, the middle end fixed mounting of support rod inner chamber has double -end motor, the both sides of double -end motor all are fixedly connected with threaded rod, the outer surface of threaded rod is connected with the moving sleeve, the outer surface fixed connection of moving sleeve has movable ring, the outer surface fixed connection of movable ring has connecting rod, the side fixed connection of connecting rod away from movable ring has connecting support, the inboard fixed connection of connecting support has heat -preserving sheath, the inboard of heat -preserving sheath is provided with electric heating sleeve.

[0006] Preferably, the bottom of the bottom plate is fixedly installed with a plurality of equally angularly distributed moving wheels.

[0007] Preferably, the upper end of the outer surface of the support rod is fixedly connected with a plurality of equally angularly distributed connecting plates, and one side of the connecting plate is fixedly connected with a fixed positioning plate.

[0008] Preferably, the both ends of the fixed positioning plate are provided with positioning slots, and one side of the inner wall of the positioning slot is provided with a movable slot.

[0009] Preferably, the both sides of the fixed positioning plate are fixedly connected with U-shaped guide rods, the upper and lower ends of the U-shaped guide rod are both slidably connected with a push plate slidably arranged in the movable slot, one side of the push plate located in the positioning slot is fixedly connected with a positioning tooth block, and a spring is fixedly connected between the two positioning tooth blocks.

[0010] Preferably, the inner side of the positioning slot is inserted with a U-shaped insert plate, the top and bottom of the inner side of the U-shaped insert plate are both fixedly connected with positioning teeth engaged with the positioning tooth block, and one side of the U-shaped insert plate is fixedly connected with a movable positioning plate corresponding to the fixed positioning plate.

[0011] Preferably, the inner sides of the movable positioning plate and the fixed positioning plate are both bonded with anti-skid rubber pads, and the inner side of the anti-skid rubber pad is provided with a cation resin cylinder.

[0012] Compared with the prior art, the utility model has the beneficial effects as follows:

[0013] 1. By the setting of the support rod, when it is necessary to replace the cation resin cylinder in the product conversion area, the external controller is used to open the double-end motor to drive the threaded rod to rotate, so that the moving sleeve moves away from the double-end motor, the movable ring moves when the moving sleeve moves, the connecting support moves through the connecting rod, and the heat-preserving sheath and the electric heating sleeve are withdrawn from the upper and lower ends of the cation resin cylinder when the connecting support moves, so that the heating equipment does not need to be frequently disassembled and assembled when the cation resin cylinder is replaced, and the use is convenient.

[0014] 2. The utility model discloses a fixed positioning plate's setting, drive pushboard when the outer surface of U type guide rod is close to each other, can cause compression to spring, and with the movement of pushboard will drive the positioning tooth block and the positioning tooth of the top and bottom inside of the U-shaped plug -in board disengages the dentition state, further can be driven through the movable positioning plate U-shaped plug -in board and exit positioning slot, make movable positioning plate and fixed positioning plate can separate fast, further convenient to take off the cation resin cylinder that needs to replace. BRIEF DESCRIPTION OF DRAWINGS

[0015] Figure 1 It is the first visual angle structure schematic drawing of the utility model;

[0016] Figure 2 It is the second visual angle sectional structure schematic drawing of the utility model;

[0017] Figure 3 It is the cooperation structure schematic drawing of the utility model double -end motor and connecting frame;

[0018] Figure 4 It is the fixed positioning plate and movable positioning plate structure schematic drawing of the utility model;

[0019] Figure 5 It is the explosion structure schematic drawing of the utility model Figure 4 .

[0020] In the drawing: 1, bottom plate;2, moving wheel;3, support rod;4, fixed positioning plate;5, connecting plate;6, antiskid rubber mat;7, cation resin cylinder;8, movable positioning plate;9, double -end motor;10, threaded rod;11, electric heating sleeve;12, heat -preserving sheath;13, connecting frame;14, connecting rod;15, movable ring;16, moving sleeve;17, U-shaped plug -in board;18, positioning tooth;19, U type guide rod;20, pushboard;21, movable groove;22, positioning slot;23, spring;24, positioning tooth block. DETAILED DESCRIPTION

[0021] The technical scheme in the embodiments of the utility model will be described clearly and completely below in conjunction with the drawings in the embodiments of the utility model, and obviously, the described embodiments are only part of the embodiments of the utility model, not all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by the ordinary skill in the art without creative labor belong to the scope of protection of the utility model.

[0022] In the description of the utility model, unless otherwise specified, the meaning of "a plurality of" is two or more than two;The orientation or position relationship indicated by the terms "upper", "lower", "left", "right", "inner", "outer", "front end", "rear end", "head", "tail" and the like is based on the orientation or position relationship shown in the drawings, which is only for the convenience of describing the utility model and simplifying the description, and does not indicate or imply that the indicated device or element must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as limiting the utility model. In addition, the terms "first", "second", "third" and the like are only for the purpose of description, and cannot be understood as indicating or implying relative importance.

[0023] In the description of the utility model, it should be pointed out that, unless otherwise specified and limited, the terms "connected", "connected" should be broadly understood, for example, it can be fixedly connected, or it can be detachably connected, or integrally connected;It can be mechanically connected, or it can be electrically connected;It can be directly connected, or it can be indirectly connected through an intermediate medium. For ordinary skilled persons in the art, the specific meaning of the above terms in the utility model can be understood according to the specific circumstances.

[0024] The bottom plate 1, the moving wheel 2, the support rod 3, the fixed positioning plate 4, the connecting plate 5, the antiskid rubber pad 6, the cation resin cylinder 7, the movable positioning plate 8, the double-head motor 9, the threaded rod 10, the electric heating sleeve 11, the heat preservation sleeve 12, the connecting frame 13, the connecting rod 14, the movable ring 15, the moving sleeve 16, the U-shaped plugboard 17, the positioning tooth 18, the U-shaped guide rod 19, the push plate 20, the movable groove 21, the positioning slot 22, the spring 23 and the positioning tooth block 24 parts of the application are general standard parts or parts known to those skilled in the art, and their structure and principle can be known by technical personnel through technical manual or through conventional experimental method.

[0025] Example one

[0026] Please refer to Figures 1-4 As shown in the utility model provides a technical scheme: a continuous fluid separation penicillin sodium production equipment, including the bottom plate 1, the middle end fixed mounting of bottom plate 1 top has support rod 3, the middle end fixed mounting of support rod 3 inner chamber has double-head motor 9, the two output ends of double-head motor 9 are all fixedly connected with threaded rod 10, the outer surface of threaded rod 10 is connected with moving sleeve 16, the outer surface of moving sleeve 16 is fixedly connected with movable ring 15, the outer surface of movable ring 15 is fixedly connected with connecting rod 14, the side away from movable ring 15 of connecting rod 14 is fixedly connected with connecting frame 13, the inner side of connecting frame 13 is fixedly connected with heat preservation sleeve 12, the inner side of heat preservation sleeve 12 is provided with electric heating sleeve 11.

[0027] The technical scheme: through the setting of the electric heating sleeve 11, the cation resin cylinder 7 in the product conversion area can be heated, the normal extraction of the equipment is guaranteed, through the setting of the supporting rod 3, when the cation resin cylinder 7 in the product conversion area needs to be replaced, the external controller is opened to drive the threaded rod 10 to rotate through the double-head motor 9, and then the moving sleeve 16 moves on the outer surface of the threaded rod 10 to the end away from the double-head motor 9, the moving sleeve 16 moves to drive the movable ring 15 to move, the movable ring 15 moves to drive the connecting rod 14 to drive the connecting frame 13 to move, and the connecting frame 13 moves to drive the heat preservation sheath 12 and the electric heating sleeve 11 to exit from the upper and lower ends of the cation resin cylinder 7, and then the cation resin cylinder 7 does not need to be frequently disassembled and assembled when being replaced, and the use is convenient.

[0028] Example two

[0029] On the basis of example one, the utility model discloses as shown in Figures 1-4 The bottom of the bottom plate 1 is fixedly installed with a plurality of equally angularly distributed moving wheels 2.

[0030] The technical scheme: through the setting of the moving wheel 2, the user can conveniently drive the equipment to move, and the convenience of position movement during use is improved.

[0031] Example three

[0032] On the basis of example one, the utility model discloses as shown in Figures 1-5 The upper end of the outer surface of the supporting rod 3 is fixedly connected with a plurality of equally angularly distributed connecting plates 5, one side of the connecting plate 5 is fixedly connected with a fixed positioning plate 4, both ends of the fixed positioning plate 4 are provided with positioning insertion grooves 22, one side of the inner wall of the positioning insertion groove 22 is provided with a movable slot 21, both sides of the fixed positioning plate 4 are fixedly connected with U-shaped guide rods 19, the upper and lower ends of the U-shaped guide rod 19 are slidably connected with push plates 20 slidably arranged in the movable slot 21, one side of the push plate 20 located at the positioning insertion groove 22 is fixedly connected with a positioning tooth block 24, the spring 23 is fixedly connected between the two positioning tooth blocks 24, the N-shaped insertion plate 17 is inserted into the inner side of the positioning insertion groove 22, the top and bottom of the inner side of the N-shaped insertion plate 17 are fixedly connected with positioning teeth 18 in mesh with the positioning tooth block 24, one side of the N-shaped insertion plate 17 is fixedly connected with a movable positioning plate 8 corresponding to the fixed positioning plate 4, the inner sides of the movable positioning plate 8 and the fixed positioning plate 4 are bonded with anti-skid rubber pads 6, the inner side of the anti-skid rubber pad 6 is provided with a cation resin cylinder 7, the number of the cation resin cylinder 7 is twenty-one, and the top of the cation resin cylinder 7 is sequentially provided with numbers.

[0033] The technical scheme: through the setting of the fixed positioning plate 4, when the push plate 20 is driven to approach each other on the outer surface of the U-shaped guide rod 19, the spring 23 can be compressed, and the movement of the push plate 20 will drive the positioning tooth block 24 to disengage from the positioning tooth 18 on the top and bottom of the inner side of the U-shaped plug plate 17, thereby the movable positioning plate 8 can drive the U-shaped plug plate 17 to exit the positioning slot 22, so that the movable positioning plate 8 and the fixed positioning plate 4 can be quickly separated, thereby facilitating the removal of the cation resin cylinder 7 to be replaced, and after the replaced cation resin cylinder 7 enters the fixed positioning plate 4, the movable positioning plate 8 drives the U-shaped plug plate 17 to reinsert into the positioning slot 22, at this time, under the assistance of the spring 23, the movable positioning plate 8 can be directly driven to approach the fixed positioning plate 4, and under the assistance of the anti-skid rubber pad 6, until the replaced cation resin cylinder 7 is fixed, at this time, the positioning tooth block 24 will automatically engage with the positioning tooth 18 under the influence of the spring 23, which is convenient for people to use.

[0034] Importantly, it should be noted that the constructions and arrangements of the present application shown in the various exemplary embodiments are by way of illustration only. Although only a few embodiments have been described in detail in this disclosure, those skilled in the art who review this disclosure will readily appreciate that many modifications are possible (e.g., variations in sizes, dimensions, structures, shapes and proportions of the various elements, values of parameters, mounting arrangements, use of materials, colors, orientations, etc.) without materially departing from the novel teachings and advantages of the subject matter described in this application. For example, elements shown as integrally formed can be constructed of multiple parts or elements, the position of elements can be reversed or otherwise varied, and the nature or number of elements or positions can be altered or varied. Accordingly, all such modifications are intended to be included within the scope of the present application. The order or sequence of any process or method steps can be changed or re-sequenced without departing from the scope of the application. In the claims, any means-plus-function clause is intended to cover the structures described herein as performing the recited function and not only structural equivalents but also equivalent structures. Other substitutions, modifications, changes, and omissions can be made in the design, operating conditions, and arrangement of the exemplary embodiments without departing from the scope of the present application. Accordingly, the present application is not limited to particular embodiments described, but extends to various modifications that nevertheless fall within the scope of the appended claims.

[0035] Furthermore, in an effort to provide a concise description of exemplary embodiments, all features of an actual implementation can not be described (i.e., those unrelated to the best mode of practicing the present application currently contemplated).

[0036] It should be explained finally that the above embodiment is only used to illustrate the technical scheme of the utility model, and is not the limit of the protection scope of the utility model, although the utility model is explained in detail with reference to the preferred embodiment, the ordinary skilled in the art should understand that the technical scheme of the utility model can be modified or replaced equivalently, and does not deviate from the essence and scope of the technical scheme of the utility model.

Claims

1. A continuous fluid separation penicillin sodium production apparatus, comprising a base plate (1), characterized in that: A support rod (3) is fixedly installed at the middle of the top of the base plate (1). A double-headed motor (9) is fixedly installed at the middle of the inner cavity of the support rod (3). Both output ends of the double-headed motor (9) are fixedly connected to threaded rods (10). A movable sleeve (16) is threadedly connected to the outer surface of the threaded rod (10). A movable ring (15) is fixedly connected to the outer surface of the movable sleeve (16). A connecting rod (14) is fixedly connected to the outer surface of the movable ring (15). A connecting frame (13) is fixedly connected to the side of the connecting rod (14) away from the movable ring (15). A heat-insulating sleeve (12) is fixedly connected to the inner side of the connecting frame (13). An electric heating sleeve (11) is provided on the inner side of the heat-insulating sleeve (12).

2. The continuous fluid separation penicillin sodium production equipment according to claim 1, characterized in that: The bottom of the base plate (1) is fixedly equipped with multiple movable wheels (2) distributed at equal angles.

3. The continuous fluid separation penicillin sodium production equipment according to claim 1, characterized in that: The upper end of the outer surface of the support rod (3) is fixedly connected to a plurality of connecting plates (5) distributed at equal angles, and a fixed positioning plate (4) is fixedly connected to one side of the connecting plate (5).

4. The continuous fluid separation penicillin sodium production equipment according to claim 3, characterized in that: The fixed positioning plate (4) has positioning slots (22) at both ends, and a movable groove (21) is provided on one side of the inner wall of the positioning slot (22).

5. The continuous fluid separation penicillin sodium production equipment according to claim 4, characterized in that: Both sides of the fixed positioning plate (4) are fixedly connected with U-shaped guide rods (19). Both the upper and lower ends of the U-shaped guide rods (19) are slidably connected with a push plate (20) that slides in the movable groove (21). The push plate (20) is fixedly connected to a positioning tooth block (24) on one side of the positioning slot (22). A spring (23) is fixedly connected between the upper and lower positioning teeth blocks (24).

6. The continuous fluid separation penicillin sodium production equipment according to claim 5, characterized in that: The inner side of the positioning slot (22) is provided with a U-shaped insert plate (17). The top and bottom of the inner side of the U-shaped insert plate (17) are fixedly connected with positioning teeth (18) that mesh with the positioning tooth block (24). A movable positioning plate (8) corresponding to the fixed positioning plate (4) is fixedly connected to one side of the U-shaped insert plate (17).

7. The continuous fluid separation penicillin sodium production equipment according to claim 6, characterized in that: The inner sides of both the movable positioning plate (8) and the fixed positioning plate (4) are bonded with anti-slip pads (6), and the inner side of the anti-slip pads (6) is provided with a cation resin cylinder (7).

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