Microcapsule particle preparation equipment

By introducing a screening chamber and a forming chamber into the microcapsule preparation equipment, and using a motor-driven sieve disc for screening and multi-directional stirring blades for mixing, the problem of uneven microcapsule size was solved, thereby improving product quality and drug efficacy.

CN223556497UActive Publication Date: 2025-11-18SHANDONG HAINENG BIOENG CO LTD
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Patent Information

Application Number
CN202422960307.8
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-03
Publication Date
2025-11-18
Estimated Expiration
2034-12-03

AI Technical Summary

Technical Problem

In existing microcapsule preparation equipment, some microcapsules are too large or too small, which affects the drug's release characteristics, stability, and bioavailability.

Method used

A microcapsule particle preparation device was designed, comprising a screening chamber and a forming chamber. The device utilizes a motor-driven fan-shaped block to generate centrifugal force, which moves the sieve disc left and right for screening. Combined with multi-directional stirring blades, the device improves the uniformity of raw material mixing, ensuring accurate screening of microcapsule particle size and efficient mixing.

Benefits of technology

This enabled accurate screening of microcapsule particles, improved product quality, ensured uniform mixing and stability of microcapsule particles, and enhanced drug release characteristics and bioavailability.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of microcapsules, and discloses microcapsule particle preparation equipment which comprises a supporting table, a screening chamber is fixedly connected to the middle of the supporting table, a square box is fixedly connected to the right side of the screening chamber, and fixing plates are fixedly connected to the inner walls of the front side and the rear side of the square box. Two guide plates are fixedly connected to the sides, close to each other, of the two fixing plates, two sliding rods are slidably connected to the inner walls of the guide plates, springs are arranged outside the sliding rods in a sleeving mode, square frames are fixedly connected to the sides, close to each other, of the sliding rods, and fixing blocks are fixedly connected to the inner walls of the square frames; a first motor is fixedly connected into the fixing block. According to the utility model, the outer wall of the sieve tray is in contact with the inner wall of the screening chamber, so that the stability and the accuracy of the sieve tray in the left-right moving process are ensured, the sizes of formed micro-capsule particles can be accurately screened, and the product quality is improved.
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Description

TECHNICAL FIELD

[0001] The utility model relates to microcapsule technical field especially relates to a microcapsule granule preparation equipment. BACKGROUND

[0002] 25-hydroxy vitamin D3 (25-OH-VD3) microcapsule granule is a kind of active form of vitamin D3 encapsulated in microcapsule preparation.25-OH-VD3 is the main storage form of vitamin D in vivo, and its half-life is longer, and stability is good, is the effective index 25 of vitamin D nutritional status.Microencapsulation technology can improve the stability and bioavailability of 25-OH-VD3, so that vitamin D3 can be more effectively absorbed and utilized by human body.

[0003] Microcapsule granule preparation equipment is a kind of industrial equipment specially used for producing microcapsule, in prior art, part of microcapsule granule preparation equipment will appear part of oversized or undersized granule in the microcapsule granule generated by forming device, if these unqualified microcapsule granule enters final product, can influence the release characteristics, stability and bioavailability of drug, so a kind of microcapsule granule preparation equipment is presented to solve the above problems. UTILITY MODEL CONTENT

[0004] In order to make up for the above shortcomings, the utility model provides a kind of microcapsule granule preparation equipment, to improve the microcapsule granule produced by part of microcapsule granule preparation equipment in prior art will appear part of oversized or undersized granule and lead to product quality problem.

[0005] In order to realize the above purpose, the utility model has adopted the following technical scheme:

[0006] A kind of microcapsule granule preparation equipment, including support platform, the middle part of the support platform is fixedly connected with screening chamber, the right side of the screening chamber is fixedly connected with square box, the front and rear two sides inner wall of the square box is fixedly connected with fixed plate, the similar side of two fixed plates is fixedly connected with two guide plates, the inner wall of the guide plate is slidably connected with two sliding rods, the outer portion of the sliding rod is equipped with spring, the similar side of multiple sliding rods is fixedly connected with square frame, the inner wall of the square frame is fixedly connected with fixed block, the inside of the fixed block is fixedly connected with motor one, the drive end of the motor one is fixedly connected with sector, the left side of two left sliding rods is fixedly connected with connecting block, the left side of the connecting block is fixedly connected with sieve tray, the top of the screening chamber is fixedly connected with forming chamber, the top of the forming chamber is fixedly connected with multidirectional adjusting assembly for increasing the uniformity of raw material;

[0007] As further description of the above technical scheme:

[0008] The adjusting assembly comprises a raw material mixing chamber, the bottom of the raw material mixing chamber is fixedly connected to the top of the forming chamber, the inner wall of the top of the raw material mixing chamber is fixedly connected with a support plate, the bottom of the support plate is fixedly connected with a second motor, the driving end of the second motor is fixedly connected with a bent plate, the inside of the bent plate is rotatably connected with a driving device, the driving end of the driving device is fixedly connected with a rotating rod, and the bottom of the rotating rod is fixedly connected with stirring blades.

[0009] As a further description of the above technical solution:

[0010] The upper inner wall of the screening chamber is fixedly connected with an upper fixed ring, the lower inner wall of the screening chamber is fixedly connected with a lower fixed ring, the top side of the sieve tray is slidingly connected to the bottom side of the upper fixed ring, the bottom side of the sieve tray is slidingly connected to the top side of the lower fixed ring, and the outer wall of the sieve tray is in contact with the inner wall of the screening chamber.

[0011] As a further description of the above technical solution:

[0012] The bottom end of the square box is fixedly connected to the top end of the support table, the far sides of the plurality of springs are fixedly connected to the close sides of the two guide plates, and the close sides of the plurality of springs are fixedly connected to the left and right outer walls of the square frame.

[0013] As a further description of the above technical solution:

[0014] The close sides of the two fixed plates are both provided with sliding grooves, and the outer wall of the square frame is slidingly connected to the inner wall of the sliding groove.

[0015] As a further description of the above technical solution:

[0016] The bottom of the screening chamber is detachably connected with a collecting box, and the bottom end of the support table is fixedly connected with support columns at four corners.

[0017] As a further description of the above technical solution:

[0018] The left and right sides of the support plate are both fixedly connected with L-shaped plates, and the close sides of the bottoms of the two L-shaped plates are rotatably connected with a square ring.

[0019] As a further description of the above technical solution:

[0020] The right side of the raw material mixing chamber is provided with a feeding port, the front and rear sides of the inside of the square ring are both rotatably connected with rotating rods, and the outside of the driving device is fixedly connected to the close sides of the two rotating rods.

[0021] The utility model has the advantages of the following:

[0022] 1. In the screening chamber, the motor one drives the fan-shaped block to rotate after starting, the semicircular shape of the fan-shaped block generates centrifugal force, and the square frame is driven to move left and right in the sliding groove through the fixed block. The square frame is fixedly connected with the sliding rod, and the sliding rod drives the sieve disc to move left and right through the connecting block. The top side of the sieve disc is slidably connected to the bottom side of the upper fixed ring, and the bottom side is slidably connected to the top side of the lower fixed ring. The outer wall of the sieve disc is in contact with the inner wall of the screening chamber, thereby ensuring the stability and accuracy of the sieve disc during left and right movement, so that the size of the formed microcapsule particles can be accurately screened, and the product quality is improved.

[0023] 2. In the utility model, the motor two drives the bending plate to rotate, the bending plate drives the driving device connected to rotate inside to rotate, and the driving device drives the stirring blade to stir the raw materials through the rotating rod. At the same time, the L-shaped plate on the left and right sides of the supporting plate cooperates with the square ring and the rotating rod to work, and the driving device is limited and supported, so that the driving device can rotate and drive the stirring blade to stir the raw materials in multiple directions. This multi-directional stirring method improves the mixing efficiency of the raw materials in the raw material mixing chamber, reduces the dead zone, and makes the raw material mixing more uniform. BRIEF DESCRIPTION OF DRAWINGS

[0024] Figure 1 A perspective view of a microcapsule particle preparation equipment is provided for the utility model;

[0025] Figure 2 A structure diagram of the screening chamber of a microcapsule particle preparation equipment is provided for the utility model;

[0026] Figure 3 For Figure 2 An enlarged view of A in the middle;

[0027] Figure 4 A structure diagram of the square box of a microcapsule particle preparation equipment is provided for the utility model;

[0028] Figure 5 For Figure 2 An enlarged view of B in the middle.

[0029] LEGEND:

[0030] 1, support table; 2, screening chamber; 3, upper fixed ring; 4, lower fixed ring; 5, sieve disc; 6, square box; 7, fixed plate; 8, guide plate; 9, sliding rod; 10, spring; 11, square frame; 12, sliding groove; 13, fixed block; 14, motor one; 15, fan-shaped block; 16, connecting block; 17, forming chamber; 18, raw material mixing chamber; 19, supporting plate; 20, motor two; 21, bending plate; 22, driving device; 23, rotating rod; 24, stirring blade; 25, L-shaped plate; 26, square ring; 27, rotating rod; 28, feeding port; 29, collection box; 30, support column. DETAILED DESCRIPTION

[0031] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all the other embodiments obtained by those skilled in the art without creative work fall within the scope of the present application.

[0032] With reference to Figure 2 , Figure 3 and Figure 4 , the present application provides an embodiment: a microcapsule particle preparation device, comprising a support table 1, the support table 1 is the basic structure of the whole microcapsule particle preparation device, which provides a stable support platform for other components of the device. Its main function is to carry various components of the device, and to ensure that the relative positions of the components remain stable during the operation of the device. The middle part of the support table 1 is fixedly connected with a screening chamber 2, the right side of the screening chamber 2 is fixedly connected with a square box 6, the bottom end of the square box 6 is fixedly connected to the top end of the support table 1, the front and rear inner walls of the square box 6 are fixedly connected with fixed plates 7, and the square box 6 plays a role in protecting the internal components. It provides a relatively closed space for the fixed plates 7 and other components, preventing external factors (such as dust, impurities, etc.) from interfering with the internal components. The proximal side of the two fixed plates 7 is fixedly connected with two guide plates 8, the inner wall of the guide plate 8 is slidingly connected with two sliding rods 9, and the fixed plate 7 provides a stable mounting position for the guide plate 8. Through the connection with the guide plate 8, the sliding of the sliding rod 9 is provided with a guide and support effect. The proximal side of the plurality of sliding rods 9 is fixedly connected with a square frame 11, the outer part of the sliding rod 9 is sleeved with a spring 10, the distal side of the plurality of springs 10 is fixedly connected to the proximal side of the two guide plates 8, the proximal side of the plurality of springs 10 is fixedly connected to the left and right outer walls of the square frame 11, and the spring 10 plays an important role in buffering and resetting during the operation of the device. The proximal side of the two fixed plates 7 is provided with a sliding groove 12, the outer wall of the square frame 11 is slidingly connected to the inner wall of the sliding groove 12, and the sliding groove 12 provides a specific track for the sliding of the square frame 11. It limits the moving direction of the square frame 11, and ensures that the square frame 11 can only slide in the left and right directions.

[0033] The inner wall of the square frame 11 is fixedly connected with a fixed block 13, the inside of the fixed block 13 is fixedly connected with a motor one 14, the driving end of the motor one 14 is fixedly connected with a fan-shaped block 15, and the main function of the guide plate 8 is to guide the sliding of the sliding rod 9. In the process of equipment operation, when the square frame 11 is driven by the centrifugal force generated by the fan-shaped block 15 of the motor one 14 to move the sliding rod 9, the guide plate 8 ensures that the sliding rod 9 can only move linearly in the left-right direction, avoiding the deviation or irregular movement of the sliding rod 9. The left side of the two left sliding rods 9 is fixedly connected with a connecting block 16, the left side of the connecting block 16 is fixedly connected with a sieve disc 5, and the connecting block 16 is a bridge between the sliding rod 9 and the sieve disc 5, which transmits the left-right movement of the sliding rod 9 to the sieve disc 5. It ensures that the sieve disc 5 connected with the sliding rod 9 can accurately move left and right to realize the screening of the microcapsule particle size. The top of the screening chamber 2 is fixedly connected with a forming chamber 17, the upper side of the screening chamber 2 is fixedly connected with an upper fixed ring 3, the lower side of the screening chamber 2 is fixedly connected with a lower fixed ring 4, the top side of the sieve disc 5 is slidingly connected to the bottom side of the upper fixed ring 3, the bottom side of the sieve disc 5 is slidingly connected to the top side of the lower fixed ring 4, and the outer wall of the sieve disc 5 is in contact with the inner wall of the screening chamber 2. The cooperation of the upper fixed ring 3 and the lower fixed ring 4 ensures the positioning accuracy of the sieve disc 5 during movement, thereby realizing the screening function of the microcapsule particle size. The bottom of the screening chamber 2 is detachably connected with a collection box 29, which can be periodically detached to collect, process or further analyze and detect the screened microcapsule particles. The bottom of the support table 1 is fixedly connected with support columns 30 at four corners.

[0034] Referring to Figure 1 , Figure 2 and Figure 5 , the top of the forming chamber 17 is fixedly connected with a multidirectional adjusting assembly for increasing the uniformity of the raw materials, and the adjusting assembly comprises a raw material mixing chamber 18, the bottom of the raw material mixing chamber 18 is fixedly connected to the top of the forming chamber 17, and the main function of the forming chamber 17 is to form microcapsules from the raw materials mixed and stirred in the raw material mixing chamber 18. The raw material mixing chamber 18 is a place for stirring and mixing raw materials. The top inner wall of the raw material mixing chamber 18 is fixedly connected with a support plate 19, the bottom of the support plate 19 is fixedly connected with a motor two 20, and the support plate 19 mainly plays a supporting and connecting role. It provides a mounting position for the motor two 20, ensuring the position stability of the motor two 20 during operation. The driving end of the motor two 20 is fixedly connected with a bent plate 21, the inside of the bent plate 21 is rotatably connected with a driving device 22, the driving end of the driving device 22 is fixedly connected with a rotating rod 23, and the bottom of the rotating rod 23 is fixedly connected with a stirring blade 24. When the motor two 20 starts, it will generate power to drive the bent plate 21 to rotate. The rotation of the bent plate 21 will drive the driving device 22 connected thereto to rotate, thereby driving the rotating rod 23 and the stirring blade 24 to stir the raw materials.

[0035] The left and right sides of the supporting plate 19 are fixedly connected with L-shaped plates 25, and the bottoms of the two L-shaped plates 25 are rotatably connected with a square ring 26 on the same side. The right side of the raw material mixing chamber 18 is provided with an inlet 28, and the inside of the square ring 26 is rotatably connected with rotating rods 27 on the front and back sides. The outside of the driving device 22 is fixedly connected with the proximal sides of the two rotating rods 27. The square ring 26 cooperates with the L-shaped plates 25 and the rotating rods 27 to limit and support the driving device 22. When the driving device 22 rotates under the drive of the bending plate 21, the square ring 26 guides and limits the movement of the driving device 22 through the rotating rods 27, so as to ensure that the rotating track of the driving device 22 meets the requirements of multi-directional stirring. At the same time, the square ring 26 also shares part of the weight and stress of the driving device 22, thereby improving the stability of the equipment operation.

[0036] Working principle: first, the raw materials are put into the raw material mixing chamber 18 through the inlet 28, and after stirring and mixing, the formed microcapsules are transferred to the screening chamber 2 by the action of the forming chamber 17. Then, the motor 14 is started to generate power to drive the fan-shaped block 15 to rotate. Since the fan-shaped block 15 is semicircular in shape, it will generate centrifugal force when rotating, thereby driving the square frame 11 to move left and right in the chute 12 in cooperation with the fixed block 13. The left and right movement of the square frame 11 drives the sliding rod 9 to move left and right, and the left and right movement of the sliding rod 9 drives the connecting block 16 to move left and right. The left and right movement of the connecting block 16 drives the sieve disc 5 to move left and right, and then the size of the formed microcapsule particles is screened by the action of the sieve disc 5.

[0037] When the driving rotary rod 23 drives the stirring blade 24 to stir the raw materials by starting the driving device 22, the motor 20 at the bottom of the supporting plate 19 is started to generate power to drive the bending plate 21 to rotate. Due to the bending design of the bending plate 21, the driving device 22 forms an angle with the vertical direction and rotates around the motor 20. In cooperation with the L-shaped plate 25 fixed outside the supporting plate 19 and the rotating rod 27 on the square ring 26, the driving device 22 can rotate and drive the stirring blade 24 to stir the raw materials in multiple directions, thereby improving the mixing efficiency of the raw materials in the raw material mixing chamber 18, reducing the dead zone, and making the raw materials more uniform.

[0038] Finally, it should be noted that the above description is only a preferred embodiment of the present application and is not intended to limit the present application. Although the present application has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent replacements to some technical features. Any modification, equivalent replacement, improvement, etc. made within the spirit and principles of the present application shall be included in the protection scope of the present application.

Claims

1. A microcapsule granule production apparatus comprising a support table (1), characterized in that: The middle part of the support table (1) is fixedly connected with a screening chamber (2), the right side of the screening chamber (2) is fixedly connected with a square box (6), the front and rear inner walls of the square box (6) are fixedly connected with fixed plates (7), the proximal sides of the two fixed plates (7) are fixedly connected with two guide plates (8), the inner walls of the guide plates (8) are slidably connected with two sliding rods (9), the outer parts of the sliding rods (9) are sleeved with springs (10), the proximal sides of the plurality of sliding rods (9) are fixedly connected with a square frame (11), the inner wall of the square frame (11) is fixedly connected with a fixed block (13), the inside of the fixed block (13) is fixedly connected with a motor one (14), the driving end of the motor one (14) is fixedly connected with a sector block (15), the left side of the two left sliding rods (9) is fixedly connected with a connecting block (16), the left side of the connecting block (16) is fixedly connected with a sieve disc (5), the top end of the screening chamber (2) is fixedly connected with a forming chamber (17), and the top of the forming chamber (17) is fixedly connected with a multidirectional adjusting assembly for increasing the uniformity of raw materials.

2. A microcapsule particle production apparatus according to claim 1, wherein: The adjusting assembly comprises a raw material mixing chamber (18), the bottom of the raw material mixing chamber (18) is fixedly connected to the top of the forming chamber (17), the top inner wall of the raw material mixing chamber (18) is fixedly connected with a support plate (19), the bottom of the support plate (19) is fixedly connected with a motor two (20), the driving end of the motor two (20) is fixedly connected with a bent plate (21), the inside of the bent plate (21) is rotatably connected with a driving device (22), the driving end of the driving device (22) is fixedly connected with a rotating rod (23), and the bottom of the rotating rod (23) is fixedly connected with stirring blades (24).

3. The apparatus of claim 1, wherein: The upper inner wall of the screening chamber (2) is fixedly connected with an upper fixed ring (3), the lower inner wall of the screening chamber (2) is fixedly connected with a lower fixed ring (4), the top side of the sieve disc (5) is slidably connected to the bottom side of the upper fixed ring (3), the bottom side of the sieve disc (5) is slidably connected to the top side of the lower fixed ring (4), and the outer wall of the sieve disc (5) is in contact with the inner wall of the screening chamber (2).

4. The apparatus of claim 1, wherein: The bottom end of the square box (6) is fixedly connected to the top end of the support table (1), the distal sides of the plurality of springs (10) are fixedly connected to the proximal sides of the two guide plates (8), and the proximal sides of the plurality of springs (10) are fixedly connected to the left and right outer walls of the square frame (11).

5. The apparatus of claim 1, wherein: The proximal sides of the two fixed plates (7) are each provided with a sliding groove (12), and the outer wall of the square frame (11) is slidably connected to the inner wall of the sliding groove (12).

6. The microcapsule particle preparation apparatus according to claim 1, wherein: The bottom of the screening chamber (2) is detachably connected with a collecting box (29), and the bottom end of the support table (1) is fixedly connected with support columns (30) at four corners.

7. The apparatus of claim 2, wherein: The left and right sides of the support plate (19) are each fixedly connected with an L-shaped plate (25), and the proximal sides of the bottoms of the two L-shaped plates (25) are rotatably connected with a square ring (26).

8. A microcapsule particle production apparatus according to claim 7, wherein: The right side of the raw material mixing chamber (18) is provided with a feeding port (28), the inside of the square ring (26) is rotatably connected with a rotating rod (27) on both sides, and the outside of the driving device (22) is fixedly connected with the proximal side of the two rotating rods (27).