Shaking device for cross-linked sodium hyaluronate gel

By designing a shaking device for cross-linked sodium hyaluronate gel, and employing multi-angle surface shaking and enhanced structural stability, the problem of low mixing efficiency in existing devices was solved, thus improving the quality of cross-linked sodium hyaluronate gel.

CN223570736UActive Publication Date: 2025-11-21BIOREGEN BIOMEDICAL (CHANGZHOU) CO LTD
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Patent Information

Application Number
CN202422947520.5
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-02
Publication Date
2025-11-21
Estimated Expiration
2034-12-02

AI Technical Summary

Technical Problem

The existing cross-linked sodium hyaluronate gel mixing chamber has low mixing efficiency, resulting in a decrease in the quality of the dry gel and the finished product.

Method used

A shaking device for cross-linked sodium hyaluronate gel was designed, including a cross-linked sodium hyaluronate gel holder, a shaking motor, a shaking disc, an inclined block, and a rib structure. The device improves mixing efficiency and enhances structural stability by shaking the gel from multiple angles.

Benefits of technology

This improved the mixing efficiency of sodium hyaluronate solution and crosslinking agent, thereby enhancing the quality of crosslinked sodium hyaluronate gel dry adhesive and finished product.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of cross-linked sodium hyaluronate gel production, in particular to a shake-up device for cross-linked sodium hyaluronate gel, which comprises a cross-linked sodium hyaluronate gel fixing frame, a cross-linked sodium hyaluronate gel shake-up motor and a cross-linked sodium hyaluronate gel shake-up disc, wherein the cross-linked sodium hyaluronate gel shake-up motor and the cross-linked sodium hyaluronate gel shake-up disc are arranged on the cross-linked sodium hyaluronate gel fixing frame; a shaking-up opening is formed in the cross-linked sodium hyaluronate gel fixing frame, a first rotating shaft and a second rotating shaft are arranged on the cross-linked sodium hyaluronate gel fixing frame, a first inclined block is arranged on the first rotating shaft, a second inclined block is arranged on the second rotating shaft, and a shaking-up main shaft and a box base are arranged on the cross-linked sodium hyaluronate gel shaking-up disc; a cross-linked sodium hyaluronate gel shake-up reaction box is arranged on the box base, a first cross-linked sodium hyaluronate gel bearing and a second cross-linked sodium hyaluronate gel bearing are arranged in the shake-up main shaft, a first cross-linked sodium hyaluronate gel clamping shaft is arranged on the first inclined block, a second cross-linked sodium hyaluronate gel clamping shaft is arranged on the second inclined block, and the cross-linked sodium hyaluronate gel shake-up reaction box is arranged on the cross-linked sodium hyaluronate gel shake-up main shaft. A guide shaft is inserted into the cross-linked sodium hyaluronate gel shaking disc, and a guide frame is arranged on the guide shaft.
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Description

TECHNICAL FIELD

[0001] The utility model relates to crosslinking sodium hyaluronate gel production technical field especially crosslinking sodium hyaluronate gel is even with shaking device. BACKGROUND

[0002] Crosslinking sodium hyaluronate gel is a kind of injection material commonly used in cosmetic and medical field, can play the role of physical antisepsis, promote wound healing, mainly used for treating skin small area mild wound surface and the disinfection of infected wound surface.

[0003] The production principle of crosslinking sodium hyaluronate gel is that first, prepare sodium hyaluronate alkaline aqueous solution of certain concentration and inject into crosslinking sodium hyaluronate gel shaking reaction box, then add crosslinking agent in the sodium hyaluronate solution in the crosslinking sodium hyaluronate gel shaking reaction box, carry out crosslinking reaction, obtain crosslinking sodium hyaluronate gel dry gel after crosslinking reaction, later, crosslinking sodium hyaluronate gel dry gel is discharged to the preset ammonium persulfate solution in secondary reaction box and carries out secondary reaction, after being fully soaked and swelling, in secondary reaction box, a large amount of water-containing ethanol is soaked and washed, and the excess crosslinking agent and by-product are removed, finally, the phosphate buffer solution is soaked and swelled in secondary reaction box, and finally, crosslinking sodium hyaluronate gel finished product is obtained.

[0004] In the above production principle process, when sodium hyaluronate solution is added to crosslinking agent for crosslinking reaction, it needs to be shaken, to ensure the quality of crosslinking sodium hyaluronate gel finished product in later period, but the existing crosslinking sodium hyaluronate gel shaking reaction box for crosslinking sodium hyaluronate gel, the whole shaking mixing efficiency between sodium hyaluronate solution and crosslinking agent is low, the quality of crosslinking sodium hyaluronate gel dry gel is reduced, and then the quality of crosslinking sodium hyaluronate gel finished product in secondary reaction box in later period is greatly reduced. UTILITY MODEL CONTENTS

[0005] The utility model discloses a crosslinking sodium hyaluronate gel shaking device for solving the above-mentioned shortcomings in the prior art.

[0006] In order to achieve the above-mentioned purpose, the utility model adopts the following technical scheme:

[0007] The utility model discloses a crosslinking sodium hyaluronate gel shakes even device, including crosslinking sodium hyaluronate gel fixing frame and the crosslinking sodium hyaluronate gel shakes even motor and crosslinking sodium hyaluronate gel shakes even tray of setting on crosslinking sodium hyaluronate gel fixing frame, the crosslinking sodium hyaluronate gel fixing frame is opened with shakes even opening, be equipped with first pivot shaft and second pivot shaft on the crosslinking sodium hyaluronate gel fixing frame, be equipped with first inclined block on the first pivot shaft, be equipped with second inclined block on the second pivot shaft, be equipped with shakes even main shaft and box base on the crosslinking sodium hyaluronate gel shakes even tray, be equipped with crosslinking sodium hyaluronate gel shakes even reaction box on the box base, be equipped with first crosslinking sodium hyaluronate gel bearing and second crosslinking sodium hyaluronate gel bearing in the shakes even main shaft,

[0008] Be equipped with first crosslinking sodium hyaluronate gel chuck shaft on the first inclined block, be equipped with second crosslinking sodium hyaluronate gel chuck shaft on the second inclined block, the top of crosslinking sodium hyaluronate gel shakes even reaction box is equipped with first inlet pipe and second inlet pipe, and the lateral wall of crosslinking sodium hyaluronate gel shakes even reaction box is equipped with exhaust pipe;

[0009] Be equipped with rib web on the box base, be equipped with guide shaft in crosslinking sodium hyaluronate gel shakes even tray, be equipped with guide frame on the guide shaft.

[0010] Further, the two ends of the first pivot shaft are fixedly arranged with the motor shaft of the crosslinking sodium hyaluronate gel shaking motor and the first inclined block, and the first pivot shaft is rotatably arranged with the crosslinking sodium hyaluronate gel fixing frame.

[0011] Further, the second pivot shaft is fixedly arranged with the second inclined block, and the second pivot shaft is rotatably arranged with the crosslinking sodium hyaluronate gel fixing frame.

[0012] Further, the first crosslinking sodium hyaluronate gel chuck shaft is fixedly sleeved with the mounting hole of the first crosslinking sodium hyaluronate gel bearing, and the second crosslinking sodium hyaluronate gel chuck shaft is fixedly sleeved with the mounting hole of the second crosslinking sodium hyaluronate gel bearing.

[0013] Further, the box base is in the shape of a trapezoid and is arranged at the top end of the crosslinking sodium hyaluronate gel shaking tray, and the rib web is symmetrically arranged in two groups, and each group has two rib webs.

[0014] Further, the guide shaft is fixedly arranged at the top end of the guide frame, and the guide shaft is rotatably inserted into the crosslinking sodium hyaluronate gel shaking tray.

[0015] Further, the guide frame is in the shape of a U and is in sliding contact with the front and rear outer sidewalls of the crosslinking sodium hyaluronate gel fixing frame.

[0016] The crosslinking sodium hyaluronate gel shaking device has the beneficial effects that:

[0017] 1. The utility model discloses a cross -linked sodium hyaluronate gel fixing frame with cross -linked sodium hyaluronate gel shaking disc is set up in the bottom of cross -linked sodium hyaluronate gel shaking reaction box, and is set up shaking main shaft and box base on the cross -linked sodium hyaluronate gel shaking disc, then the first pivot with first inclined block is set up on the cross -linked sodium hyaluronate gel fixing frame, and the second pivot with second inclined block is set up, realize the sodium hyaluronate solution and cross -linking agent in the sodium hyaluronate solution and cross -linking agent in the box base on the cross -linked sodium hyaluronate gel shaking reaction box are shaken and mixed effect of comprehensive effective swing of multi -angle face, improve the shaking mixed efficiency between sodium hyaluronate solution and cross -linking agent as a whole, improve the quality of the cross -linked sodium hyaluronate gel dry glue made in the cross -linked sodium hyaluronate gel shaking reaction box, and further greatly improve the finished product quality of the cross -linked sodium hyaluronate gel made in the secondary reaction box.

[0018] 2. The utility model discloses a rib plate structure is set up between cross -linked sodium hyaluronate gel shaking reaction box and box base, further improve the structural stability between cross -linked sodium hyaluronate gel shaking reaction box and box base in the swing shaking process. ACCURACY

[0019] Figure 1 It is the overall structure first perspective solid drawing of the utility model;

[0020] Figure 2 It is the overall structure front view section of the utility model;

[0021] Figure 3 It is the overall structure second perspective solid drawing of the utility model; Figure 2 It is the local enlarged view of Y in the utility model;

[0022] Figure 4 It is the overall structure second perspective solid drawing of the utility model;

[0023] Figure 5 It is the overall structure overhead view schematic drawing of the utility model.

[0024] In the drawing: 1 cross -linked sodium hyaluronate gel fixing frame;11 cross -linked sodium hyaluronate gel shaking motor;12 shakes and mixes the opening;2 first pivot;21 first inclined block;22 first cross -linked sodium hyaluronate gel axle;3 second pivot;31 second inclined block;32 second cross -linked sodium hyaluronate gel axle;4 cross -linked sodium hyaluronate gel shaking disc;5 shaking main shaft;51 first cross -linked sodium hyaluronate gel bearing;52 second cross -linked sodium hyaluronate gel bearing;6 box base;61 rib plate;7 cross -linked sodium hyaluronate gel shaking reaction box;71 first inlet pipe;72 second inlet pipe;73 discharge pipe;8 guide frame;81 guide shaft. SPECIFIC EMBODIMENTS

[0025] The technical solutions in the embodiments of the present application will be clearly and completely described with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments.

[0026] With reference to Figures 1-5 The crosslinked sodium hyaluronate gel uniform shaking device comprises a crosslinked sodium hyaluronate gel fixing frame 1, a crosslinked sodium hyaluronate gel uniform shaking motor 11 and a crosslinked sodium hyaluronate gel uniform shaking disc 4 arranged on the crosslinked sodium hyaluronate gel fixing frame 1, a uniform shaking opening 12 is formed in the crosslinked sodium hyaluronate gel fixing frame 1, a first rotating shaft 2 and a second rotating shaft 3 are arranged on the crosslinked sodium hyaluronate gel fixing frame 1, a first inclined block 21 is arranged on the first rotating shaft 2, a second inclined block 31 is arranged on the second rotating shaft 3, a uniform shaking main shaft 5 and a box base 6 are arranged on the crosslinked sodium hyaluronate gel uniform shaking disc 4, a crosslinked sodium hyaluronate gel uniform shaking reaction box 7 is arranged on the box base 6, and a first crosslinked sodium hyaluronate gel bearing 51 and a second crosslinked sodium hyaluronate gel bearing 52 are arranged in the uniform shaking main shaft 5.

[0027] A first crosslinked sodium hyaluronate gel clamping shaft 22 is arranged on the first inclined block 21, a second crosslinked sodium hyaluronate gel clamping shaft 32 is arranged on the second inclined block 31, a first inlet pipe 71 and a second inlet pipe 72 are arranged at the top end of the crosslinked sodium hyaluronate gel uniform shaking reaction box 7, and a discharge pipe 73 is arranged on the side wall of the crosslinked sodium hyaluronate gel uniform shaking reaction box 7.

[0028] A rib plate 61 is arranged on the box base 6, a guide shaft 81 is inserted on the crosslinked sodium hyaluronate gel uniform shaking disc 4, and a guide frame 8 is arranged on the guide shaft 81.

[0029] The crosslinked sodium hyaluronate gel fixing frame 1 is fixedly installed through preset bolts, so that the uniform shaking stability is ensured.

[0030] The two ends of the first rotating shaft 2 are fixedly arranged with a motor shaft of the crosslinked sodium hyaluronate gel uniform shaking motor 11 and the first inclined block 21, respectively, and the first rotating shaft 2 is rotationally arranged with the crosslinked sodium hyaluronate gel fixing frame 1; the crosslinked sodium hyaluronate gel uniform shaking motor 11 is a constant-speed motor and is durable.

[0031] The second rotating shaft 3 is fixedly arranged with the second inclined block 31, and the second rotating shaft 3 is rotationally arranged with the crosslinked sodium hyaluronate gel fixing frame 1, so that the multi-angle surface swinging uniform shaking effect of the crosslinked sodium hyaluronate gel uniform shaking disc 4 is ensured.

[0032] The first cross-linked sodium hyaluronate gel card shaft 22 is fixedly sleeved with the mounting hole of the first cross-linked sodium hyaluronate gel bearing 51, and the second cross-linked sodium hyaluronate gel card shaft 32 is fixedly sleeved with the mounting hole of the second cross-linked sodium hyaluronate gel bearing 52, so that when the cross-linked sodium hyaluronate gel shaking disc 4 is shaken on the multi-angle surface, the first cross-linked sodium hyaluronate gel card shaft 22 is prevented from slipping out of the first cross-linked sodium hyaluronate gel bearing 51, and the second cross-linked sodium hyaluronate gel card shaft 32 is prevented from slipping out of the second cross-linked sodium hyaluronate gel bearing 52.

[0033] The box base 6 is in a trapezoidal structure as a whole and is arranged at the top end of the cross-linked sodium hyaluronate gel shaking disc 4. The rib plates 61 are symmetrically arranged in two groups, each group having two rib plates 61. The rib plates 61 are made of hard alloy steel and have high strength and are not deformed.

[0034] The guide shaft 81 is fixedly arranged at the top end of the guide frame 8 and is rotationally connected with the cross-linked sodium hyaluronate gel shaking disc 4. When the guide frame 8 slides along the front and rear outer side walls of the cross-linked sodium hyaluronate gel fixing frame 1, the cross-linked sodium hyaluronate gel shaking disc 4 itself is shaken on the multi-angle surface at the same time. At this time, the guide shaft 81 rotates in the preset through hole of the cross-linked sodium hyaluronate gel shaking disc 4, so as to ensure the shaking effect.

[0035] The guide frame 8 is in a U-shaped structure as a whole and is in sliding contact with the front and rear outer side walls of the cross-linked sodium hyaluronate gel fixing frame 1. When the cross-linked sodium hyaluronate gel shaking disc 4 is shaken on the multi-angle surface, the guide frame 8 is guided to slide along the front and rear outer side walls of the cross-linked sodium hyaluronate gel fixing frame 1, so as to improve the guiding stability.

[0036] Working mode: a certain amount of sodium hyaluronate alkaline aqueous solution is injected into the cross-linked sodium hyaluronate gel shaking reaction box 7 through the first inlet pipe 71, then the preset valve on the first inlet pipe 71 is closed, then a certain amount of cross-linking agent is injected into the cross-linked sodium hyaluronate gel shaking reaction box 7 through the second inlet pipe 72, and the preset valve on the second inlet pipe 72 is closed, then the cross-linking reaction is carried out in the cross-linked sodium hyaluronate gel shaking reaction box 7, and the cross-linked sodium hyaluronate gel dry gel is obtained after the cross-linking reaction is completed. (It is prior art and has been described in the background art);

[0037] During the cross-linking reaction, the cross-linking sodium hyaluronate gel shaking motor 11 can be started, and the motor shaft of the cross-linking sodium hyaluronate gel shaking motor 11 drives the first rotating shaft 2 to rotate at a constant speed, and in turn drives the first inclined block 21, the second inclined block 31 and the second rotating shaft 3 to rotate at a constant speed. At this time, the first cross-linking sodium hyaluronate gel shaft 22 on the first inclined block 21 will give the first cross-linking sodium hyaluronate gel bearing 51 a rotating top force due to the overall inclination, and at the same time, the second cross-linking sodium hyaluronate gel shaft 32 on the second inclined block 31 will give the second cross-linking sodium hyaluronate gel bearing 52 a rotating top force due to the overall inclination. That is, the cross-linking sodium hyaluronate gel shaking disc 4 in the shaking opening 12 can be fully and effectively shaken at multiple angles, the sodium hyaluronate solution and the cross-linking agent in the cross-linking sodium hyaluronate gel shaking reaction box 7 on the box base 6 can be fully and effectively shaken at multiple angles, the shaking and mixing efficiency between the sodium hyaluronate solution and the cross-linking agent is improved, the quality of the cross-linking sodium hyaluronate gel dry gel prepared in the cross-linking sodium hyaluronate gel shaking reaction box 7 is improved, and the quality of the finished product of the cross-linking sodium hyaluronate gel prepared in the secondary reaction box is greatly improved.

[0038] In addition, by arranging the rib plate 61 structure between the cross-linking sodium hyaluronate gel shaking reaction box 7 and the box base 6, the structural stability during the shaking process is further improved.

[0039] The above is only a preferred specific embodiment of the present application, but the protection scope of the present application is not limited thereto. Any skilled person in the art can make equivalent replacements or changes according to the technical scheme and the inventive concept of the present application within the technical range disclosed by the present application, which should be covered within the protection scope of the present application.

Claims

1. A shaking device for cross-linked sodium hyaluronate gel, comprising a cross-linked sodium hyaluronate gel holder (1) and a cross-linked sodium hyaluronate gel shaking motor (11) and a cross-linked sodium hyaluronate gel shaking disc (4) disposed on the cross-linked sodium hyaluronate gel holder (1), characterized in that: The cross-linked sodium hyaluronate gel holder (1) has a shaking opening (12), the cross-linked sodium hyaluronate gel holder (1) has a first rotating shaft (2) and a second rotating shaft (3), the first rotating shaft (2) has a first inclined block (21), the second rotating shaft (3) has a second inclined block (31), the cross-linked sodium hyaluronate gel shaking plate (4) has a shaking main shaft (5) and a box base (6), the box base (6) has a cross-linked sodium hyaluronate gel shaking reaction box (7), the shaking main shaft (5) has a first cross-linked sodium hyaluronate gel bearing (51) and a second cross-linked sodium hyaluronate gel bearing (52). The first inclined block (21) is provided with a first cross-linked sodium hyaluronate gel retainer (22), the second inclined block (31) is provided with a second cross-linked sodium hyaluronate gel retainer (32), the top of the cross-linked sodium hyaluronate gel shaking reaction box (7) is provided with a first inlet pipe (71) and a second inlet pipe (72), and the side wall of the cross-linked sodium hyaluronate gel shaking reaction box (7) is provided with an outlet pipe (73). The base (6) of the box is provided with a rib plate (61), the cross-linked sodium hyaluronate gel shaking plate (4) is provided with a guide shaft (81), and the guide shaft (81) is provided with a guide frame (8).

2. The shaking apparatus for cross-linked sodium hyaluronate gel according to claim 1, characterized in that: The two ends of the first rotating shaft (2) are respectively fixed to the motor shaft of the cross-linked sodium hyaluronate gel shaking motor (11) and the first inclined block (21), and the first rotating shaft (2) is rotatably set with the cross-linked sodium hyaluronate gel fixing frame (1).

3. The shaking apparatus for cross-linked sodium hyaluronate gel according to claim 1, characterized in that: The second rotating shaft (3) is fixedly set with the second inclined block (31), and the second rotating shaft (3) is rotatably set with the cross-linked sodium hyaluronate gel holder (1).

4. The shaking apparatus for cross-linked sodium hyaluronate gel according to claim 1, characterized in that: The first cross-linked sodium hyaluronate gel clip (22) is fixedly sleeved with the mounting hole of the first cross-linked sodium hyaluronate gel bearing (51), and the second cross-linked sodium hyaluronate gel clip (32) is fixedly sleeved with the mounting hole of the second cross-linked sodium hyaluronate gel bearing (52).

5. The shaking apparatus for cross-linked sodium hyaluronate gel according to claim 1, characterized in that: The base (6) is a trapezoidal structure and is located at the top of the cross-linked sodium hyaluronate gel shaking dish (4). The ribs (61) are arranged in two symmetrical groups, with two ribs in each group.

6. The shaking apparatus for cross-linked sodium hyaluronate gel according to claim 1, characterized in that: The guide shaft (81) is fixedly installed at the top of the guide frame (8), and the guide shaft (81) is rotatably connected to the cross-linked sodium hyaluronate gel shaking disk (4).

7. The shaking apparatus for cross-linked sodium hyaluronate gel according to claim 1, characterized in that: The guide frame (8) is U-shaped and slides in contact with the front and rear outer walls of the cross-linked sodium hyaluronate gel fixation frame (1).