Immunodetection kit

By introducing storage boxes, sterilization boxes, and isolation plates into the immunoassay kit, the problems of reduced detection accuracy and reagent strip contamination caused by tilting and contamination have been solved, achieving higher detection accuracy and efficiency.

CN223575169UActive Publication Date: 2025-11-21SHENZHEN HOSPITAL CANCER HOSPITAL CHINESE ACAD OF MEDICAL SCI
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Patent Information

Application Number
CN202422549833.5
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-10-22
Publication Date
2025-11-21
Estimated Expiration
2034-10-22

AI Technical Summary

Technical Problem

Existing immunoassay kits suffer from reduced accuracy due to instability caused by tilting, difficulty in precisely adjusting the angle of the test strips, and internal contamination leading to test strip contamination and scrapping.

Method used

An immunoassay kit was designed, comprising a storage box, a disinfection box, an isolation plate, a suction cup, a hinge, and a puncture needle. The kit uses a desiccant to preserve the test strips, a magnetic disinfectant spray to disinfect hands, an isolation plate to prevent contamination, a puncture needle to seal the collection solution, a suction cup to fix the kit, a telescopic rod to mix the liquid, a balance shaft to adjust the angle of the test strips, and an observation window to monitor the detection progress.

Benefits of technology

It improves the accuracy and efficiency of testing, avoids testing errors and reagent strip waste caused by tilting and contamination, ensures the cleanliness and stability of the reagent kit, and enhances the reliability and speed of testing.

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Abstract

The utility model relates to the technical field of immunodetection kits, and discloses an immunodetection kit which comprises an equipment body, a storage box is arranged in the equipment body, a disinfection box is inserted into one side of the equipment body, and the equipment body, the storage box, the disinfection box and a disinfection spray are inserted into one side of the equipment body. The device is reasonable in structure, the telescopic rod holes are formed in the two sides of the device body, the telescopic rods are inserted into the telescopic rod holes, the telescopic rods enable the springs to extrude and deform, the protruding blocks arranged in the springs extrude the elastic rubber rings, the gears in the elastic rubber rings extrude the collecting pipes, and collecting liquid and culture liquid in the collecting pipes are fully and evenly mixed; the problem that the detection result is inaccurate due to non-uniform mixing of the collected liquid is avoided; the collection tube is sealed by the sealing cover, so that the pollution of the culture liquid in the collection tube is avoided, and the problem that the detection reagent is invalid due to pollution is prevented; the lower surface of the collection tube is punctured to enable the collected liquid in the collection tube to flow into the detection test strip; the detection efficiency is improved, and the detection accuracy is improved.
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Description

Technical Field

[0001] This utility model relates to the field of immunoassay kits, specifically to an immunoassay kit. Background Technology

[0002] Immunoassay is a method that uses immunological principles to determine the content of a analyte in a sample by using the analyte as an antigen or antibody. A test kit is a box containing chemical reagents for detecting chemical components, drug residues, virus types, etc. Some test kits typically contain multiple reagent vials, requiring the use of a pipette to draw the reagents from the vials and then transfer them to an ELISA plate for immunoassay.

[0003] An immunoassay kit disclosed in Chinese Utility Model Patent Application Publication CN220315942U, while employing a locking mechanism between the reservoir and assembly box to facilitate the removal of the required reagent from the assembly box during use, and with the cover plate sliding against the reservoir to make retrieving reagents from different reservoirs more convenient and reduce reagent contamination, does not solve the problems of reduced detection accuracy due to instability caused by tilting, the precise angle adjustment of the reagent strips, and the contamination of the test strips due to internal contamination of the test kit. Therefore, this utility model is proposed to address the above problems. Utility Model Content

[0004] (a) Technical problems to be solved

[0005] To address the shortcomings of existing technologies, this invention provides an immunoassay kit that solves the problems of reduced detection accuracy due to instability caused by tilting, precise angle adjustment and positioning of the test strips, and contamination and scrapping of the test strips due to internal contamination of the test kit.

[0006] (II) Technical Solution

[0007] To achieve the above objectives, this utility model is implemented through the following technical solution: an immunoassay kit, comprising a device body (1), a storage box (2) inside the device body (1), a disinfection box (3) inserted into one side of the device body (1), a disinfection spray (4) inside the disinfection box (3), a suction cup (5) on the lower surface of the device body (1), an isolation plate (6) inserted into the inside of the device body (1), a hinge (7) rotatably connected to one side of the device body (1), a device cover plate (8) on one side of the hinge (7), a puncture needle (9) inside the device cover plate (8), a puncture cap (10) inserted into the inside of the device cover plate (8), and telescopic rods (11) inserted into both sides of the device body (1), the outer surface of the telescopic rods (11) being sleeved with... There is a spring (12), and an elastic rubber ring (13) is provided on one side of the spring (12). A collection tube (14) is provided inside the elastic rubber ring (13). A sealing cap (15) is inserted into the collection tube (14). A balance shaft seat (16) is provided inside the main body of the device (1). A balance connecting block (17) is rotatably connected inside the balance shaft seat (16). A balance frame (18) is provided on one side of the balance connecting block (17). An adjustment shaft seat (19) is inserted into the balance frame (18). An adjustment rod (20) is rotatably connected inside the adjustment shaft seat (19). A detection strip frame (21) is sleeved on one side of the adjustment rod (20). A counterweight block (22) is fixedly connected to the lower surface of the detection strip frame (21). A test strip (23) is provided inside the detection strip frame (21).

[0008] Optionally, the device body (1) has grooves on both sides near the middle, the grooves are adapted to the isolation plate (6), and a temperature sensor is provided on one side of the device body (1).

[0009] Optionally, a magnetic strip is provided on one side of the inside of the disinfection box (3), and an iron ring is fitted on the outer surface of the disinfection spray (4). The iron ring and the magnetic strip are compatible with each other. An arc groove is provided on one side of the disinfection box (3) near the upper surface. The arc groove is the same size as the disinfection spray (4).

[0010] Optionally, a hinge (7) is threaded through one side of the device body (1) by a fixing bolt, and a device cover plate (8) is threaded through one side of the hinge (7) by a bolt, and the number of the hinges (7) is two.

[0011] Optionally, the storage box (2) has a desiccant groove inside, and the device body (1) has a drying box near one side inside. The drying box and the storage box (2) are filled with desiccant, and the drying box is hollow inside.

[0012] Optionally, the interior of the elastic rubber ring (13) is hollow, and the interior of the elastic rubber ring (13) is provided with a gear-shaped groove.

[0013] Optionally, the inside of the collection tube (14) is hollow, and a connecting strip is provided on one side of the collection tube (14) and the sealing cap (15).

[0014] Optionally, the counterweight (22) is semi-circular in shape, and the plane of the counterweight (22) is fixedly connected to the lower surface of the detection frame (21).

[0015] In summary, the technical effects and advantages of this utility model are as follows:

[0016] 1. This utility model has a reasonable structure. The device cover is opened by a hinge, and the test strips are stored inside the storage box of the device body. A drying groove is opened on one side of the storage box to dry the test strips stored inside, avoiding the problem of inaccurate test results due to moisture inside the box. The disinfection spray is fixed by a magnetic strip inside the disinfection box. Pressing the disinfection spray disinfects the hands, avoiding the influence of bacteria on the sampling and inaccurate test results. The isolation plate divides the inside into a sampling area and a testing area to prevent accidental contamination of the device body during the sampling process, thus avoiding the waste of internal test strips and preventing re-contamination. The puncture needle inside the device cover punctures the inside of the collection tube to allow the internal sampling liquid and culture medium to flow onto the test strip. The puncture needle cap seals the puncture needle to prevent contamination. The suction cup fixes the device body to help keep the internal test strips in a horizontal position, avoiding misalignment of the collection tube and test strip due to test misalignment, thus improving the detection accuracy.

[0017] 2. In this utility model, telescopic rod holes are provided on both sides of the device body, and telescopic rods are inserted into the telescopic rod holes. The telescopic rods cause the spring to deform and compress the elastic ring through the protrusions inside the spring. The gears inside the elastic ring then compress the collection tube, ensuring that the collection liquid and culture medium inside are fully and evenly mixed. This avoids the problem of inaccurate test results due to uneven mixing of the collection liquid. The sealing cap seals the collection tube to prevent contamination of the internal culture medium and to prevent the test reagents from becoming ineffective due to contamination. The collection liquid inside flows into the test strip by puncturing the lower surface of the collection tube.

[0018] 3. In this utility model, a balance connecting block is rotatably connected inside the balance shaft seat. The balance connecting block drives the balance frame to adjust to a horizontal position. The counterweight causes the adjusting rods on both sides of the test strip frame to adjust the angle of the test strip frame, keeping the test strip inside horizontal. This allows the drop frame on the upper surface of the test strip to quickly immerse the reagent strip inside the test strip while maintaining a horizontal position, making the detection time faster and more accurate. It also avoids the overflow of the sample collected inside the drop frame due to displacement and tilt. The drop frame has spikes inside, allowing the collection tube to be inserted into the collection hole on the upper surface of the device cover, so that the spikes can penetrate into the collection tube. The sample collected inside flows into the drop frame along the spikes. The test strip is located on the side of the device body near the storage box. The observation window on the upper surface of the device cover allows you to see the detection status of the test strip and the dripping of the collected sample, greatly improving the detection efficiency. Attached Figure Description

[0019] Figure 1 This is a schematic diagram of the structure of this utility model;

[0020] Figure 2 This is a schematic diagram of the multifunctional exploded structure of the device of this utility model;

[0021] Figure 3 This is a schematic diagram of the exploded structure of the extrusion mixing device of this utility model;

[0022] Figure 4 This is a schematic diagram of the exploded structure of the structural balancing and stabilizing device of this utility model.

[0023] In the diagram: 1. Equipment body; 2. Storage box; 3. Disinfection box; 4. Disinfection spray; 5. Suction cup; 6. Isolation plate; 7. Hinge; 8. Equipment cover; 9. Puncture needle; 10. Puncture needle cover; 11. Telescopic rod; 12. Spring; 13. Elastic rubber ring; 14. Collection tube; 15. Sealing cover; 16. Balance shaft seat; 17. Balance connecting block; 18. Balance frame; 19. Adjusting shaft seat; 20. Adjusting rod; 21. Detection strip frame; 22. Counterweight; 23. Test strip. Detailed Implementation

[0024] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0025] Example: Reference Figures 1-4An immunoassay kit is shown, comprising a device body 1, a storage box 2 inside the device body 1, a disinfection box 3 inserted into one side of the device body 1, a disinfection spray 4 inside the disinfection box 3, a suction cup 5 on the lower surface of the device body 1, an isolation plate 6 inserted into the inside of the device body 1, a hinge 7 rotatably connected to one side of the device body 1, a device cover 8 on one side of the hinge 7, a puncture needle 9 inside the device cover 8, a puncture needle cap 10 inserted into the inside of the device cover 8, and telescopic rods 11 inserted into both sides of the device body 1. Springs 12 are sleeved on the outer surface of the telescopic rods 11. One side of the device is provided with an elastic rubber ring 13, inside which is provided a collection tube 14, and inside the collection tube 14 is a sealing cap 15. Inside the device body 1 is provided a balance shaft seat 16, inside which is rotatably connected a balance connecting block 17. One side of the balance connecting block 17 is provided with a balance frame 18, inside which is inserted an adjustment shaft seat 19, inside which is rotatably connected an adjustment rod 20, one side of the adjustment rod 20 is fitted with a detection strip frame 21, the lower surface of the detection strip frame 21 is fixedly connected with a counterweight block 22, and inside the detection strip frame 21 is provided a test strip 23.

[0026] As a preferred embodiment of this example, Figure 2As shown, the device body 1 has a storage box 2 inside, a disinfection box 3 inserted into one side of the device body 1, a disinfection spray 4 inside the disinfection box 3, a suction cup 5 on the lower surface of the device body 1, an isolation plate 6 inserted into the inside of the device body 1, a hinge 7 rotatably connected to one side of the device body 1, a device cover 8 on one side of the hinge 7, a puncture needle 9 inside the device cover 8, a puncture needle cover 10 inserted into the inside of the device cover 8, grooves are formed on both sides of the inside of the device body 1 near the middle, the grooves are adapted to the isolation plate 6, and a temperature... A temperature sensor is present. A magnetic strip is located on one side of the interior of the disinfection box 3. An iron ring is fitted onto the outer surface of the disinfection spray 4, and the iron ring and magnetic strip are compatible. An arc-shaped groove, the same size as the disinfection spray 4, is located on one side of the disinfection box 3 near its upper surface. A fixing bolt is located inside the device body 1, with its thread penetrating the hinge 7, the device body 1, and the device cover 8. A desiccant recess is located inside the storage box 2. A desiccant box is located near one side of the interior of the device body 1. Both the desiccant box and the storage box 2 contain desiccant, and the interior of the desiccant box is hollow. During use, the device cover 8 is opened via hinge 2, and the reagent strips are stored inside the storage box 2 within the device body 1. A drying groove on one side of the storage box 2 allows the desiccant inside to dry and preserve the stored reagent strips, preventing inaccurate test results due to moisture inside the box. The disinfection spray 4 is secured by a magnetic strip inside the disinfection box 3. Pressing the disinfection spray 4 disinfects the hands, preventing bacteria on the hands from affecting sampling and causing inaccurate test results. The partition 6 divides the interior into a sampling area and a testing area. To prevent accidental contamination of the device body 1 during sampling, thus avoiding the waste of internal reagent strips and preventing re-contamination, a puncture needle inside the device cover 8 is used to puncture the inside of the collection tube 14, allowing the sampling liquid and culture medium inside to flow out onto the test strip 23. The puncture needle 9 is sealed and stored by the puncture needle cover 10 to prevent contamination of the puncture needle. The suction cup 5 fixes the device body 1 to help keep the internal test strip 23 in a horizontal position, preventing misalignment and tilting of the collection tube 14, which would cause the test strip 23 to misalign, thus improving the detection accuracy.

[0027] like Figure 2 and Figure 3As shown, in this embodiment, telescopic rods 11 are inserted into both sides of the device body 1. A spring 12 is sleeved on the outer surface of the telescopic rod 11. An elastic rubber ring 13 is provided on one side of the spring 12. A collection tube 14 is provided inside the elastic rubber ring 13, and a sealing cap 15 is inserted inside the collection tube 14. The elastic rubber ring 13 is hollow and has a gear-shaped groove inside. The collection tube 14 is also hollow, and a connecting strip is provided on one side of the collection tube 14 and the sealing cap 15. During use, telescopic rod holes are provided on both sides of the device body 1. An internal telescopic rod 11 is inserted, which compresses and deforms the spring 12. The protrusion inside the spring 12 compresses the elastic ring 13, and the gear inside the elastic ring 13 compresses the collection tube 14, ensuring that the collection solution and culture solution inside are fully mixed and uniform. This avoids the problem of inaccurate test results due to uneven mixing of the collection solution. The sealing cap 15 seals the collection tube 14 to prevent contamination of the internal culture solution and to prevent the test reagent from becoming ineffective due to contamination. The collection solution inside flows into the test strip 23 by puncturing the lower surface of the collection tube 14.

[0028] As shown in the figure and Figure 4 As shown, in this embodiment, the device body 1 has a balance shaft seat 16 inside, a balance connecting block 17 is rotatably connected inside the balance shaft seat 16, a balance frame 18 is provided on one side of the balance connecting block 17, an adjustment shaft seat 19 is inserted inside the balance frame 18, an adjustment rod 20 is rotatably connected inside the adjustment shaft seat 19, a detection strip frame 21 is sleeved on one side of the adjustment rod 20, a counterweight 22 is fixedly connected to the lower surface of the detection strip frame 21, a test strip 23 is provided inside the detection strip frame 21, the counterweight 22 is semi-circular in shape, and the plane of the counterweight 22 is fixedly connected to the lower surface of the detection strip frame 21. During use, the balance connecting block 17 is rotatably connected inside the balance shaft seat 16, the balance connecting block 17 drives the balance frame 18 to be adjusted to the horizontal direction, and the counterweight 22 makes the detection strip frame 23... The adjusting rods 20 on both sides drive the detection strip frame 21 to adjust its angle, so that the detection strip 23 inside is kept horizontal. The drop frame on the upper surface of the detection strip 23 is kept horizontal and quickly immersed in the reagent strip inside the detection strip 23, making the detection time faster and more accurate. It avoids the overflow of the sample collected inside the drop frame due to displacement and tilt. The spikes inside the drop frame allow the collection tube 14 to be inserted into the collection hole on the upper surface of the device cover plate 8, so that the spikes can be inserted into the inside of the collection tube 14. The sample collected inside flows into the inside of the drop frame along the spikes. The detection strip 23 is located on the side of the device body 1 near the storage box 2. The detection status of the detection strip 23 and the drop status of the collected sample can be seen through the observation window on the upper surface of the device cover plate 8, which greatly improves the detection efficiency.

[0029] The working principle of this practical application is as follows:

[0030] During use, the device cover 8 is opened via hinge 2, and the reagent strips are stored inside the storage box 2 within the device body 1. A drying groove on one side of the storage box 2 allows the desiccant inside to dry and preserve the stored reagent strips, preventing inaccurate test results due to moisture inside the box. The disinfection spray 4 is secured by a magnetic strip inside the disinfection box 3. Pressing the disinfection spray 4 disinfects the hands, preventing bacteria on the hands from affecting sampling and causing inaccurate test results. The partition 6 divides the interior into a sampling area and a testing area, preventing accidental contamination of the device body 1 during sampling and thus avoiding the waste of the internal reagent strips and preventing recontamination. A puncture needle inside the device cover 8 punctures the inside of the collection tube 14, allowing the sampling liquid and culture medium inside to flow out onto the test strip 23. The puncture needle 9 is sealed and stored by the puncture needle cover 10 to prevent contamination. The device body 1 is fixed by the suction cup 5 to help keep the internal test strip 23 horizontal, preventing misalignment and tilting of the collection tube 14, thus improving detection accuracy. Telescopic rod holes are provided on both sides of the device body 1, and telescopic rods 11 are inserted into these holes. The telescopic rods 11 cause the spring 12 to deform, and the protrusions inside the spring 12 compress the elastic ring 13, causing the elastic ring 13 to... The gears squeeze the collection tube 14 to ensure that the collection liquid and culture medium inside are fully mixed evenly, avoiding inaccurate test results due to uneven mixing of the collection liquid. The sealing cap 15 seals the collection tube 14 to prevent contamination of the internal culture medium and to prevent the test reagents from becoming ineffective due to contamination. By puncturing the lower surface of the collection tube 14, the collection liquid inside flows into the test strip 23. The balance connecting block 17 is rotatably connected inside the balance shaft seat 16. The balance connecting block 17 drives the balance frame 18 to be adjusted to a horizontal position. The counterweight 22 causes the adjusting rods 20 on both sides of the test strip frame 21 to adjust the angle of the test strip frame 21, so that the test strip 23 inside is kept horizontal. The test strip 23 is positioned so that the droplet frame on its upper surface is quickly immersed in the reagent strip inside the test strip 23 while maintaining a horizontal position. This makes the detection time faster and more accurate, and avoids the overflow of the sample collected inside the droplet frame due to displacement or tilting. The droplet frame has spikes inside, which allow the collection tube 14 to be inserted into the collection hole on the upper surface of the device cover plate 8 so that the spikes can penetrate into the collection tube 14. The sample collected inside flows into the droplet frame along the spikes. Since the test strip 23 is located on the side of the device body 1 near the storage box 2, the detection status of the test strip 23 and the droplet status of the collected sample can be seen through the observation window on the upper surface of the device cover plate 8, which greatly improves the detection efficiency.

[0031] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. An immunoassay kit, comprising a device body (1), characterized in that: The device body (1) has a storage box (2) inside. A disinfection box (3) is inserted into one side of the device body (1). A disinfection spray (4) is installed inside the disinfection box (3). A suction cup (5) is installed on the lower surface of the device body (1). An isolation plate (6) is inserted into the inside of the device body (1). A hinge (7) is rotatably connected to one side of the device body (1). A device cover plate (8) is installed on one side of the hinge (7). A puncture needle (9) is installed inside the device cover plate (8). A puncture needle cover (10) is inserted into the inside of the device cover plate (8). Telescopic rods (11) are inserted into both sides of the device body (1). A spring (12) is sleeved on the outer surface of the telescopic rod (11). An elastic spring is installed on one side of the spring (12). The elastic rubber ring (13) has a collection tube (14) inside, and a sealing cap (15) is inserted inside the collection tube (14). The device body (1) has a balance shaft seat (16) inside, and a balance connecting block (17) is rotatably connected inside the balance shaft seat (16). A balance frame (18) is provided on one side of the balance connecting block (17). An adjustment shaft seat (19) is inserted inside the balance frame (18). An adjustment rod (20) is rotatably connected inside the adjustment shaft seat (19). A detection strip frame (21) is sleeved on one side of the adjustment rod (20). A counterweight block (22) is fixedly connected to the lower surface of the detection strip frame (21). A test strip (23) is provided inside the detection strip frame (21).

2. The immunoassay kit according to claim 1, characterized in that: The device body (1) has grooves on both sides near the middle, and the grooves are adapted to the isolation plate (6). A temperature sensor is provided on one side of the device body (1).

3. An immunoassay kit according to claim 1, characterized in that: A magnetic strip is provided on one side of the inside of the disinfection box (3), and an iron ring is fitted on the outer surface of the disinfection spray (4). The iron ring and the magnetic strip are compatible with each other. An arc groove is provided on one side of the disinfection box (3) near the upper surface. The arc groove is the same size as the disinfection spray (4).

4. An immunoassay kit according to claim 1, characterized in that: One side of the device body (1) is threaded with a hinge (7) through a fixing bolt, and one side of the hinge (7) is threaded with a device cover plate (8) through a bolt. The number of the hinges (7) is two.

5. An immunoassay kit according to claim 1, characterized in that: The storage box (2) has a desiccant groove inside, and the device body (1) has a drying box near one side inside. The drying box and the storage box (2) are filled with desiccant, and the drying box is hollow inside.

6. An immunoassay kit according to claim 1, characterized in that: The interior of the elastic rubber ring (13) is hollow, and the interior of the elastic rubber ring (13) is provided with gear-shaped grooves.

7. An immunoassay kit according to claim 1, characterized in that: The inside of the collection tube (14) is hollow, and a connecting strip is provided on one side of the collection tube (14) and the sealing cap (15).

8. An immunoassay kit according to claim 1, characterized in that: The counterweight (22) is semi-circular in shape, and the plane of the counterweight (22) is fixedly connected to the lower surface of the detection frame (21).

Citation Information

Patent Citations

  • Immunodetection kit

    CN220315942U