Fish living body toxicology monitoring device based on fluorescent carbon dot mediation

Abstract

The utility model relates to the technical field of living body imaging monitoring, and particularly discloses a fluorescent carbon dot mediated fish living body toxicology monitoring device which comprises a fixing mechanism, the fixing mechanism comprises a fish tank to be monitored and a positioning rail plate, a positioning sliding groove is formed in the lower surface of the positioning rail plate, and a second threaded rod and a movable plate are arranged in the positioning sliding groove; the monitoring mechanism comprises a base, imaging display equipment and a tracking assembly, the imaging display equipment is installed on the base, and the tracking assembly comprises a transverse guide rail fixedly installed on the positioning rail plate and a longitudinal linear motor arranged on the transverse guide rail; according to the device, the in-phosphor imaging scanning lens with the infrared sensor is arranged, the infrared sensor on the in-phosphor imaging scanning lens can capture the position of a sample in real time and transmit the position information to the control device, and therefore the position of the in-phosphor imaging scanning lens can be adjusted in real time.

Description

TECHNICAL FIELD

[0001] The utility model belongs to the in vivo imaging monitoring technical field, concretely relates to a kind of fish in vivo toxicology monitoring device based on fluorescent carbon dot mediation. BACKGROUND

[0002] In vivo imaging is a kind of technology for qualitative and quantitative analysis of biological processes at cell and molecular levels in vivo, which mainly includes bioluminescence, fluorescent carbon dots, isotope imaging and X-ray imaging method, and in vivo imaging technology can be used to observe tumor growth and metastasis, infectious disease development process, expression of specific genes and other biological processes in vivo animal, and the pathological condition of animal can be monitored using the technology;

[0003] Since fish is aquatic animal, physiological needs can be met by keeping in water, so that its vitality and normal behavior can be ensured during imaging process, therefore, when carrying out in vivo pathological research on fish animal, container with water needs to be used for monitoring, and during monitoring process, fish will move irregularly, and traditional imaging mode cannot accurately follow the motion trail of fish, so as to affect monitoring effect.

[0004] Therefore, the person skilled in the art proposes a fish in vivo toxicology monitoring device based on fluorescent carbon dot mediation to solve the problems proposed in the background art.

[0005] The above information disclosed in the background art is only used to increase the understanding of the background art of the utility model, so it can include prior art known by those skilled in the art. CONTENT OF UTILITY MODEL

[0006] The utility model aims at providing a fish in vivo toxicology monitoring device based on fluorescent carbon dot mediation to solve the problems proposed in the above background art.

[0007] To achieve the above object, the utility model provides the following technical scheme:

[0008] A fish in vivo toxicology monitoring device based on fluorescent carbon dot mediation, comprising:

[0009] The fixing mechanism comprises a fish tank to be monitored and a positioning track plate, the upper surface of the fish tank to be monitored is provided with a containing groove, the lower surface of the positioning track plate is provided with a positioning sliding groove, the inside of the positioning sliding groove is provided with a second threaded rod and a moving plate, the moving plate is fixedly connected with a clamping plate, the number of clamping plates is two, and the two clamping plates are respectively in extrusion fit with the two side surfaces of the fish tank to be monitored.

[0010] The utility model provides a monitoring mechanism, the monitoring mechanism includes base, imaging display device and tracking component, the imaging display device is installed on the base, the tracking component includes fixedly installed lateral guide rail on the positioning track plate and sets up longitudinal linear motor on the lateral guide rail, sets up the lifting slide on longitudinal linear motor, fixedly installs fluorescent body in vivo imaging scanning lens on the lifting slide, electric connection has infrared sensor on the fluorescent body in vivo imaging scanning lens, all are provided with wireless signal emission module on fluorescent body in vivo imaging scanning lens and infrared sensor, the fluorescent body in vivo imaging scanning lens is connected with imaging display device through wireless signal emission module.

[0011] Preferably, the longitudinal linear motor is provided with a first slot on one surface, and the lifting slide is installed in the first slot and is in sliding fit with the first slot.

[0012] Preferably, the lateral guide rail is provided with a second slot on one surface, and the first threaded rod and the lateral moving block are arranged in the second slot, the first threaded rod is in threaded fit with the lateral moving block, and the longitudinal linear motor is fixedly installed on the lateral moving block.

[0013] Preferably, the lateral guide rail is fixedly installed with a driving motor on one side, the output end of the driving motor is connected with the first threaded rod, the driving motor and the longitudinal linear motor are electrically connected with the control device, the control device is provided with a wireless signal receiving module, and the wireless signal receiving module is in communication connection with the wireless signal emission module.

[0014] Preferably, the moving plate is provided with a threaded hole on one surface, and the second threaded rod is screwed with the threaded hole.

[0015] Preferably, the positioning track plate is installed with a crank handle on one side, and one end of the crank handle is connected with the second threaded rod.

[0016] Compared with the prior art, the utility model has the beneficial effects that:

[0017] (1) The utility model discloses a fluorescent body in vivo imaging scanning lens with an infrared sensor, a lateral guide rail and a longitudinal linear motor, when the fish needs to be imaged and monitored, the prepared fluorescent carbon dots are injected into the fish, and then the fish is placed in the fish tank to be monitored, the infrared sensor on the fluorescent body in vivo imaging scanning lens can capture the position of the sample in real time, and the position information is transmitted to the control device, and then the control device drives the driving motor and the longitudinal linear motor, so that the position of the fluorescent body in vivo imaging scanning lens can be adjusted in real time, and the position of the sample can be followed, and the imaging monitoring is facilitated.

[0018] (2)The utility model discloses a second threaded rod with a crank handle is set, and the thread on second threaded rod is divided into opposite two sections, two moving plates are respectively with two sections of thread and screw, can according to the size of the fish tank to be monitored, rotate the crank handle, with two clamping plates respectively to two sides or the middle movement, thereby can provide carrier for monitoring mechanism.

[0019] The above summary is intended to illustrate, but not limit, the present application in any way. Further aspects, embodiments and features of the present application will be readily apparent from the drawings and detailed description below. BRIEF DESCRIPTION OF DRAWINGS

[0020] Figure 1 It is the three-dimensional structure schematic diagram of the utility model;

[0021] Figure 2 It is the longitudinal linear motor specific structure schematic diagram of the utility model;

[0022] Figure 3 It is the right view of the utility model;

[0023] Figure 4 It is the positioning rail plate specific structure schematic diagram of the utility model.

[0024] In the drawing: 1, the fish tank to be monitored;2, containing groove;3, base;4, imaging display device;5, horizontal guide rail;6, positioning rail plate;7, longitudinal linear motor;8, first slot;9, lifting slide block;10, fluorescent body internal imaging scanning lens;11, second slot;12, first threaded rod;13, drive motor;14, wireless signal receiving module;15, control device;16, moving plate;17, clamping plate;18, positioning sliding groove;19, crank handle;20, second threaded rod. DETAILED DESCRIPTION

[0025] The technical solutions in the embodiments of the present application will be described clearly and completely below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all the other embodiments obtained by those skilled in the art without creative work fall within the scope of protection of the present application.

[0026] Embodiment one:

[0027] Please refer to Figures 1-4 As shown in the figure, a fish live body toxicology monitoring device based on fluorescent carbon dot mediation, comprising:

[0028] The fixing mechanism comprises a fish tank 1 to be monitored and a positioning track plate 6, the upper surface of the fish tank 1 is provided with a containing groove 2, the lower surface of the positioning track plate 6 is provided with a positioning sliding groove 18, the inside of the positioning sliding groove 18 is provided with a second threaded rod 20 and a moving plate 16, the moving plate 16 is fixedly connected with clamping plates 17, the number of the clamping plates 17 is two, and the two clamping plates 17 are respectively in extrusion fit with the two side surfaces of the fish tank 1 to be monitored;

[0029] The monitoring mechanism comprises a base 3, an imaging display device 4 and a tracking assembly, the imaging display device 4 is installed on the base 3, the tracking assembly comprises a horizontal guide rail 5 fixedly installed on the positioning track plate 6 and a longitudinal linear motor 7 arranged on the horizontal guide rail 5, the longitudinal linear motor 7 is provided with a lifting sliding block 9, the lifting sliding block 9 is fixedly installed with a fluorescent body internal imaging scanning lens 10, the fluorescent body internal imaging scanning lens 10 is electrically connected with an infrared sensor, the fluorescent body internal imaging scanning lens 10 and the infrared sensor are both provided with wireless signal transmitting modules, and the fluorescent body internal imaging scanning lens 10 is in communication connection with the imaging display device 4 through the wireless signal transmitting module.

[0030] Specifically, the longitudinal linear motor 7 is provided with a first slot 8 on one surface, the lifting sliding block 9 is installed in the first slot 8, and the lifting sliding block 9 is in sliding fit with the first slot 8.

[0031] Specifically, the horizontal guide rail 5 is provided with a second slot 11 on one surface, the second slot 11 is provided with a first threaded rod 12 and a horizontal moving block, the first threaded rod 12 is in threaded fit with the horizontal moving block, and the longitudinal linear motor 7 is fixedly installed on the horizontal moving block.

[0032] Specifically, the horizontal guide rail 5 is fixedly installed with a driving motor 13 on one side, the output end of the driving motor 13 is connected with the first threaded rod 12, the driving motor 13 and the longitudinal linear motor 7 are both electrically connected with a control device 15, the control device 15 is provided with a wireless signal receiving module 14, and the wireless signal receiving module 14 is in communication connection with the wireless signal transmitting module.

[0033] As can be seen from the above, the device is provided with the fluorescent body internal imaging scanning lens 10 with the infrared sensor, the horizontal guide rail 5 and the longitudinal linear motor 7, when the live imaging monitoring operation of the fish is needed, the prepared fluorescent carbon dots can be injected into the body of the fish, and then the fish is placed into the fish tank 1 to be monitored, at this time, the monitoring mechanism is installed on the fish tank 1 to be monitored through the fixing mechanism with the clamping plates 17, the infrared sensor on the fluorescent body internal imaging scanning lens 10 can capture the position of the sample in real time, and the position information is transmitted to the control device 15, and then the control device 15 drives the driving motor 13 and the longitudinal linear motor 7 respectively, so that the position of the fluorescent body internal imaging scanning lens 10 can be adjusted in real time, and the fluorescent body internal imaging scanning lens 10 can follow the position of the sample, thereby facilitating the imaging monitoring.

[0034] Embodiment two:

[0035] Please refer to Figures 1-4 As shown, the mobile plate 16 is provided with a threaded hole on one surface, and the second threaded rod 20 is screwed with the threaded hole.

[0036] Specifically, the positioning rail plate 6 is provided with a crank 19 on one side, and one end of the crank 19 is connected with the second threaded rod 20.

[0037] From the above, the device is provided with the second threaded rod 20 with the crank 19, and the threads on the second threaded rod 20 are divided into two opposite sections, and the two mobile plates 16 are screwed with the two sections of threads, respectively.

[0038] The standard parts used in the utility model can be purchased from the market, and the special-shaped parts can be ordered according to the description and the drawings, the specific connection mode of each part adopts the conventional means such as bolt, rivet and welding in the prior art, the mechanical parts and equipment adopt the conventional type in the prior art, and the circuit connection adopts the conventional connection mode in the prior art, which will not be described in detail here. The contents not described in detail in the specification all belong to the prior art known to those skilled in the art.

[0039] In the description of the utility model, the terms "first", "second" are only used for description purpose, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of indicated technical features. Therefore, the features limited by "first", "second" can be explicitly or implicitly included one or more features. The meaning of "multiple" is two or more, unless otherwise specifically limited.

[0040] In the utility model, unless otherwise specifically defined and limited, the terms "installation", "connection", "connection", "fixing" and the like should be understood in a broad sense, for example, it can be fixed connection, or detachable connection, or integrated; it can be mechanical connection, or electrical connection; it can be directly connected, or indirectly connected through intermediate medium, it can be the communication or interaction relationship between two elements. For those skilled in the art, the specific meaning of the above terms in the utility model can be understood according to the specific circumstances.

[0041] In the present application, unless otherwise explicitly specified and limited, the first feature is "on" or "under" the second feature, which can be direct contact between the first and second features, or indirect contact through an intermediate medium. Moreover, the first feature "above", "above" and "above" the second feature can be directly above or obliquely above the first feature, or only indicate that the horizontal height of the first feature is higher than that of the second feature. The first feature "below", "below" and "below" the second feature can be directly below or obliquely below the first feature, or only indicate that the horizontal height of the first feature is less than that of the second feature.

[0042] In the description of the present application, the description of the terms "one embodiment", "some embodiments", "example", "specific example" or "some examples" means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present application. In the present application, the illustrative description of the above terms is not necessarily directed to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner. In addition, the skilled in the art can combine and combine the different embodiments or examples described in the present application and the features of the different embodiments or examples without contradiction.

[0043] The present application discloses the embodiment of the drawing, only relates to the structure related to the embodiment of the present application, other structures can refer to the usual design, in the case of no conflict, the same embodiment and different embodiments of the present application can be combined with each other.

[0044] Although the embodiments of the present application have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of the present application, and the scope of the present application is defined by the appended claims and their equivalents.

Claims

1.A device for monitoring the toxicity of fish in vivo based on fluorescent carbon dots, characterized in that, Include: The fixing mechanism, the fixing mechanism includes the fish tank (1) to be monitored and the positioning track plate (6), the upper surface of the fish tank (1) to be monitored is provided with containing groove (2), the lower surface of the positioning track plate (6) is provided with positioning sliding groove (18), the inside of the positioning sliding groove (18) is provided with second threaded rod (20) and moving plate (16), the moving plate (16) is fixedly connected with clamping plate (17), the number of the clamping plate (17) is two, two the clamping plate (17) is respectively with the two side surfaces of the fish tank (1) to be monitored extrusion fit; The monitoring mechanism, the monitoring mechanism includes base (3), imaging display device (4) and tracking assembly, the imaging display device (4) is installed on base (3), the tracking assembly includes fixedly installed on positioning track plate (6) transverse guide rail (5) and sets up on transverse guide rail (5) longitudinal linear motor (7), the longitudinal linear motor (7) is provided with lifting slide block (9), the lifting slide block (9) is fixedly installed with fluorescent body internal imaging scanning lens (10), the fluorescent body internal imaging scanning lens (10) is electrically connected with infrared sensor, the fluorescent body internal imaging scanning lens (10) and infrared sensor are all provided with wireless signal transmitting module, the fluorescent body internal imaging scanning lens (10) is connected with imaging display device (4) through wireless signal transmitting module. 2.The fish in vivo toxicological monitoring device based on fluorescent carbon dots mediation according to claim 1, characterized in that: The surface of the longitudinal linear motor (7) is provided with first slot (8), the lifting slide block (9) is installed in the first slot (8), and the lifting slide block (9) is in sliding fit with the first slot (8). 3.The fish in vivo toxicological monitoring device based on fluorescent carbon dots mediation according to claim 1, characterized in that: The surface of the transverse guide rail (5) is provided with second slot (11), the first threaded rod (12) and the transverse moving block are arranged in the second slot (11), the first threaded rod (12) is in threaded fit with the transverse moving block, and the longitudinal linear motor (7) is fixedly installed on the transverse moving block. 4.The device according to claim 3, wherein the device is characterized in that: The driving motor (13) is fixedly installed on one side of the transverse guide rail (5), the output end of the driving motor (13) is connected with the first threaded rod (12), and the control device (15) is electrically connected with the driving motor (13) and the longitudinal linear motor (7), the wireless signal receiving module (14) is arranged on the control device (15), and the wireless signal receiving module (14) is connected with the wireless signal transmitting module. 5.The device according to claim 1, wherein the device is characterized in that: The surface of the moving plate (16) is provided with a threaded hole, and the second threaded rod (20) is screwed with the threaded hole. 6.The device according to claim 5, wherein the device is characterized in that: The side surface of the positioning track plate (6) is provided with a crank (19), and one end of the crank (19) is connected with the second threaded rod (20).

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