Rectal administration device in bioequivalence test

Abstract

The utility model belongs to the technical field of bioequivalence tests, and particularly relates to a rectal administration device in a bioequivalence test, which comprises a mounting box and a medicine delivery component arranged on the outer side of the end part of the mounting box, the medicine feeding assembly comprises a mounting plate, a motor and a rotating disc, and the inner side of one end of the mounting box is fixedly connected with the mounting plate; the release position and depth of the medicine can be accurately controlled through the medicine feeding assembly, it is ensured that the medicine can reach a target area in the rectum, accurate control over the medicine dosage can be achieved through the device, the consistency of the dosage every time is ensured, and according to a traditional rectal administration mode, manual insertion and manual medicine injection are possibly needed; this may cause discomfort or pain of an injected person, while the drug delivery assembly can complete the drug delivery process instantly, thereby reducing the pain of organisms.

Description

TECHNICAL FIELD

[0001] The utility model belongs to the technical field of bioequivalence test, specifically relates to a rectal administration device in bioequivalence test. BACKGROUND

[0002] Bioequivalence (BE) test refers to the human test that uses the method of bioavailability research to compare the absorption degree and speed of active ingredients of the same or different preparations of the same drug under the same test conditions by taking pharmacokinetic parameters as indexes. The rectal administration device plays a key role in this test. It can directly send the drug into the rectum, make the drug rapidly absorbed into the blood circulation through the rectal mucosa, thereby avoiding the first pass effect of the liver and improving the bioavailability of the drug.

[0003] However, the traditional administration method needs more manual operation, which leads to a relatively slow administration speed, increases the waiting time in the administration process, lacks auxiliary mechanism, and the administration position may be difficult to accurately control, so the drug may not accurately reach the target area in the rectum, thereby affecting the absorption and treatment effect of the drug. The traditional administration method needs to manually insert the drug, which may increase discomfort and pain, and reduce acceptance.

[0004] Therefore, a rectal administration device in bioequivalence test is designed to solve the above problems. UTILITY MODEL CONTENTS

[0005] To solve the problems in the background art, the utility model provides a rectal administration device in bioequivalence test. The drug delivery assembly can accurately control the release position and depth of the drug, ensuring that the drug reaches the target area in the rectum. The device can accurately control the drug dose and ensure the consistency of the drug amount each time. The traditional rectal administration method may need to be manually inserted and then manually injected, which may cause discomfort or pain in the injected person. The drug delivery assembly can complete the administration process in an instant, reducing the pain of the organism. Since the drug delivery assembly can accurately control the release force of the drug, unnecessary damage to the rectal wall can be avoided.

[0006] To achieve the above purpose, the utility model provides the following technical scheme: a rectal administration device in bioequivalence test, comprising a mounting box, further comprising a drug delivery assembly arranged on the outer side of the end portion of the mounting box.

[0007] The medicine feeding assembly comprises a mounting plate, a motor and a rotating disc, one end inner side of the mounting box is fixedly connected with the mounting plate, one side of the mounting plate is provided with the motor, the main shaft outer side of the motor is fixedly connected with a dial disc, the main shaft outer side of the motor is rotatably connected with the rotating disc, the one side upper surface of the rotating disc is fixedly connected with a limiting column, one end outer side of the rotating disc is rotatably connected with a pull rod, the end inner side of the pull rod is rotatably connected with a sliding rod, the end outer side of the sliding rod is fixedly connected with a top head, the outer side of the sliding rod is slidably connected with the end inner side of the mounting plate, and one end outer side of the mounting box is in communication with a feeding head.

[0008] Preferably, the outer side of the sliding rod is provided with a spring, and the two ends of the spring are fixedly connected with one end outer side of the sliding rod and the inner side of the mounting plate.

[0009] Preferably, one end outer side of the feeding head is in communication with a feeding inlet.

[0010] Preferably, the outer side of the top head is fixedly connected with a rubber ring, and the rubber ring is made of rubber.

[0011] Preferably, the inner side of the top head is annularly provided with a plurality of air holes.

[0012] Preferably, the outer side of the feeding head is fixedly connected with a baffle, and the baffle is made of silica gel.

[0013] Preferably, the end upper surface of the mounting box is fixedly connected with a medicine placing box, and the inside of the medicine placing box is fixedly connected with a partition plate.

[0014] Compared with the prior art, the application has the beneficial effects that: the medicine feeding assembly is added to the application, the medicine feeding assembly can accurately control the release position and depth of the medicine, and ensures that the medicine can reach the target area in the rectum, the device can accurately control the dose of the medicine, and ensures the consistency of the dose each time, the traditional rectal administration method may need to be manually inserted and then manually injected, which may cause discomfort or pain of the injected person, and the medicine feeding assembly can complete the administration process in an instant, reduces the pain, and since the design of the medicine feeding assembly can accurately control the release strength of the medicine, unnecessary damage to the rectal wall can be avoided. BRIEF DESCRIPTION OF DRAWINGS

[0015] The accompanying drawings are used to provide further understanding of the present application and constitute a part of the specification, which are used together with embodiments of the present application to explain the present application and do not constitute a limitation to the present application. In the drawings:

[0016] Figure 1 It is a whole structure schematic view of the present application;

[0017] Figure 2 It is a sectional view of the mounting box in the present application;

[0018] Figure 3 It is a structure schematic view of the slide rod and the top head in the present application;

[0019] Figure 4 It is a structure schematic view of the mounting plate in the present application;

[0020] Figure 5 It is a structure schematic view of the medicine box and the partition plate in the present application;

[0021] Figure 6 It is a structure schematic view of the feeding head and the feeding port in the present application.

[0022] In the drawings:

[0023] 1, mounting box;

[0024] 2, medicine feeding assembly; 21, mounting plate; 22, motor; 23, rotating disc; 24, push disc; 25, limiting column; 26, pull rod; 27, slide rod; 28, top head; 29, spring; 210, feeding head; 211, feeding port; 212, rubber ring; 213, air hole; 214, baffle; 215, medicine box; 216, partition plate. DETAILED DESCRIPTION

[0025] The technical solutions in the embodiments of the present application will be described clearly and completely below in conjunction with the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all the other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0026] As Figure 1 shown;

[0027] A rectal administration device in a bioequivalence test, comprising a mounting box 1.

[0028] In this embodiment: However, the traditional administration method may require more manual operation, resulting in a relatively slow administration speed, increasing the waiting time during administration, lacking auxiliary mechanisms, and the administration position may be difficult to control accurately, the drug may not accurately reach the target area in the rectum, affecting the absorption and treatment effect of the drug, the traditional administration method requires manual insertion of the drug, which may increase discomfort and pain, and reduce acceptance. In order to solve this technical problem, the drug delivery assembly 2 is added on this basis.

[0029] Further:

[0030] As shown in Figures 1 to 6 :

[0031] In combination with the above: The drug delivery assembly 2 includes a mounting plate 21, a motor 22, and a rotating disc 23. One end of the mounting box 1 is fixedly connected with the mounting plate 21. The motor 22 is installed on one side of the mounting plate 21. The outer side of the main shaft of the motor 22 is fixedly connected with a dial plate 24. The outer side of the main shaft of the motor 22 is rotatably connected with the rotating disc 23. The upper surface of one side of the rotating disc 23 is fixedly connected with a limiting column 25. The outer side of one end of the rotating disc 23 is rotatably connected with a pull rod 26. The inner side of the end of the pull rod 26 is rotatably connected with a sliding rod 27. The outer side of the end of the sliding rod 27 is fixedly connected with a top head 28. The outer side of the sliding rod 27 is slidably connected with the inner side of the end of the mounting plate 21. One end of the outer side of the mounting box 1 is connected with a feeding head 210. The outer side of the sliding rod 27 is provided with a spring 29. The outer sides of both ends of the spring 29 are respectively fixedly connected with the outer side of one end of the sliding rod 27 and the inner side of the mounting plate 21. The outer side of one end of the feeding head 210 is connected with an inlet 211. The outer side of the top head 28 is fixedly connected with a rubber ring 212. The material of the rubber ring 212 is rubber. The inner side of the top head 28 is annularly provided with a plurality of air holes 213. The outer side of the feeding head 210 is fixedly connected with a baffle 214. The material of the baffle 214 is silica gel.

[0032] In the embodiment, when the user uses the device, the user can put the medicine into the inside of the feeding head 210 through the feeding port 211, at this time, the user can insert the feeding head 210 into the part where the medicine needs to be delivered, at this time, the user can start the motor 22, the motor 22 drives the jockey plate 24 on the outside of the main shaft to rotate, the jockey plate 24 rotates and contacts the limiting column 25 at the same time, at this time, the jockey plate 24 drives the limiting column 25 to continue to rotate, until the jockey plate 24 drives the limiting column 25 to rotate by 180 degrees, the jockey plate 24 loses the thrust force to the limiting column 25, at this time, the elastic potential energy stored in the spring 29 is released, under the action of the spring 29, the pull rod 26 rebounds quickly, and then drives the slide rod 27 on one side of the pull rod 26 to rebound quickly, at this time, the top head 28 at the end of the slide rod 27 can drive the medicine in the feeding head 210 to be ejected quickly, the outside of the top head 28 is in sliding connection with the inside of the feeding head 210, and the rubber ring 212 can ensure that all the medicine is discharged from the feeding head 210. The air-permeable hole 213 opened in the top head 28 can prevent gas from entering the body, and the baffle 214 can shield the part where the medicine is injected into the organism, protect privacy, and improve the use experience. The delivery assembly 2 can accurately control the release position and depth of the medicine, and ensure that the medicine can reach the target area in the rectum. The device can accurately control the dose of the medicine, and ensure the consistency of the dose each time. The traditional rectal administration method may need to be manually inserted and then manually injected, which may cause discomfort or pain to the injected person. The delivery assembly 2 can complete the injection process in an instant, reducing pain. Since the design of the delivery assembly 2 can accurately control the release force of the medicine, unnecessary damage to the rectal wall can be avoided.

[0033] Further,

[0034] In an optional embodiment, the end upper surface of the installation box 1 is fixedly connected with a medicine storage box 215.

[0035] In the embodiment, the medicine storage box 215 provides a safe and clean storage space for the medicine, avoiding contamination or damage of the medicine during transportation or storage. The reasonable design of the medicine storage box 215 enables the medicine to be easily taken, without the need for complicated searching or arranging during the administration process. The required medicine can be quickly taken from the medicine storage box 215 and loaded into the device, thereby shortening the preparation time for administration.

[0036] Further,

[0037] In an optional embodiment, the inside of the medicine storage box 215 is fixedly connected with a partition plate 216.

[0038] In this embodiment: the partition plate 216 can separate the inside space of the medicine box 215 into multiple small areas, so that different types of medicines or different doses of medicines can be stored separately, avoiding confusion between medicines. Through reasonable design of the number and position of the partition plate 216, the classification management of medicines can be realized, and medical staff can quickly find the required medicines.

[0039] Working principle: when the user uses the device, the user can put the medicine into the inside of the feeding head 210 through the feeding port 211, at this time the user can insert the feeding head 210 into the part where the medicine needs to be sent, at this time the user can start the motor 22, the motor 22 drives the jockey plate 24 on the outside of the main shaft to rotate, the jockey plate 24 rotates while contacting the limiting column 25, at this time the jockey plate 24 drives the limiting column 25 to continue rotating, until the jockey plate 24 drives the limiting column 25 to rotate 180 degrees, the jockey plate 24 loses the thrust force to the limiting column 25, at this time the elastic potential energy stored in the spring 29 is released, under the action of the spring 29, the pull rod 26 rebounds quickly, and then drives the slide rod 27 on one side of the pull rod 26 to rebound quickly, at this time the top head 28 at the end of the slide rod 27 can drive the medicine in the feeding head 210 to be ejected quickly, the outside of the top head 28 is in sliding connection with the inside of the feeding head 210, and at the same time the rubber ring 212 can ensure that all the medicine is discharged from the feeding head 210. The top head 28 is provided with a ventilation hole 213, which can prevent gas from entering the body. The baffle 214 can shield the part where the medicine is injected into the organism, protect privacy, and improve the use experience. The medicine release position and depth can be accurately controlled through the medicine feeding assembly 2, so that the medicine can reach the target area in the rectum. Through the device, the dose of the medicine can be accurately controlled, and the consistency of the dose each time can be ensured. The traditional rectal administration method may need to be manually inserted and then manually injected, which may cause discomfort or pain to the injected person. The medicine feeding assembly 2 can complete the injection process in an instant, reducing pain. Since the design of the medicine feeding assembly 2 can accurately control the release force of the medicine, unnecessary damage to the rectal wall can be avoided. The medicine box 215 provides a safe and clean storage space for the medicine, avoiding contamination or damage of the medicine during transportation or storage. The reasonable design of the medicine box 215 makes it easy to access the medicine, so that the user does not need to search or arrange the medicine during the injection process. The required medicine can be quickly taken out from the medicine box 215 and loaded into the device, thereby shortening the preparation time for injection. The partition plate 216 can separate the inside space of the medicine box 215 into multiple small areas, so that different types of medicines or different doses of medicines can be stored separately, avoiding confusion between medicines. Through reasonable design of the number and position of the partition plate 216, the classification management of medicines can be realized, and medical staff can quickly find the required medicines.

[0040] Finally, it should be noted that: the above only for the preferred embodiments of the present application, and is not intended to limit the present application, although the foregoing embodiments of the present application have been described in detail, for the skilled in the art, it still can be modified, or for the equivalent replacement of part of the technical features of the technical solutions recorded in the foregoing embodiments. Any modification, equivalent replacement, improvement, etc. made within the spirit and principles of the present application, shall be included within the scope of the present application.

Claims

1. A rectal administration device for use in bioequivalence trials, comprising a mounting box (1), characterized in that: The medicine feeding assembly (2) is arranged outside the end of the mounting box (1); The medicine feeding assembly (2) comprises a mounting plate (21), a motor (22) and a rotating disc (23), one end of the mounting box (1) is fixedly connected with the mounting plate (21), one side of the mounting plate (21) is provided with the motor (22), the outer side of the main shaft of the motor (22) is fixedly connected with a rotating disc (24), the outer side of the main shaft of the motor (22) is rotatably connected with the rotating disc (23), the upper surface of one side of the rotating disc (23) is fixedly connected with a limiting column (25), the outer side of one end of the rotating disc (23) is rotatably connected with a pull rod (26), the inner side of the end of the pull rod (26) is rotatably connected with a sliding rod (27), the outer side of the end of the sliding rod (27) is fixedly connected with a top head (28), the outer side of the sliding rod (27) is slidably connected with the inner side of the end of the mounting plate (21), and the outer side of one end of the mounting box (1) is in communication with a feeding head (210).

2. The rectal administration device for bioequivalence test according to claim 1, wherein: The outer side of the sliding rod (27) is provided with a spring (29), and the outer sides of both ends of the spring (29) are fixedly connected with the outer side of one end of the sliding rod (27) and the inner side of the mounting plate (21) respectively.

3. The rectal dosing device for bioequivalence testing of claim 1, wherein: The outer side of one end of the feeding head (210) is in communication with an inlet (211).

4. The rectal dosing device for bioequivalence testing of claim 1, wherein: The outer side of the top head (28) is fixedly connected with a rubber ring (212), and the rubber ring (212) is made of rubber.

5. The rectal dosing device for bioequivalence testing of claim 4, wherein: The inner side of the top head (28) is annularly provided with a plurality of air holes (213).

6. The rectal dosing device for bioequivalence testing of claim 1, wherein: The outer side of the feeding head (210) is fixedly connected with a baffle (214), and the baffle (214) is made of silica gel.

7. The rectal dosing device for bioequivalence testing of claim 1, wherein: The end surface of the mounting box (1) is fixedly connected with a medicine placing box (215), and the inner side of the medicine placing box (215) is fixedly connected with a partition plate (216).

Images