A collagen salting-out device
By designing a collagen salting-out device with a delivery pipe and a stirring rack, the problem of collagen layering and covering in high-salt solutions was solved, achieving a more efficient salting-out effect.
Patent Information
- Application Number
- CN202423075821.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-13
- Publication Date
- 2025-11-28
- Estimated Expiration
- 2034-12-13
AI Technical Summary
Existing collagen salting-out devices have a simple structure, which makes it easy for collagen to overlap and cover each other when added to high-salt-concentration solutions, reducing the contact area and affecting the salting-out effect.
Design a device comprising a barrel body, a barrel lid, a stirring rack, a conveying pipe, and a motor drive system. By rotating the conveying pipe and stirring the stirring rack, the collagen can be conveyed and stirred at multiple points, thereby increasing the contact area.
It effectively prevents collagen from overlapping and covering, improves the salting-out effect, increases the contact area between collagen and high-salt solutions, and enhances salting-out efficiency.
Smart Images
Figure CN223602063U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to collagen production auxiliary technical field especially relates to a collagen salt precipitation device. BACKGROUND
[0002] Collagen salt precipitation is a process that uses high salt concentration to reduce the solubility of collagen, so that it precipitates out of solution. This method is commonly used for protein separation and purification. Collagen is a long-chain protein composed of tripeptide helix structure, with multiple hydrophilic and hydrophobic groups. When collagen is added to a high-concentration salt solution, salt ions interact with collagen to form electrostatic neutralization, hydration and ion-ion interaction, resulting in a decrease in solubility of collagen, which precipitates out;
[0003] The common collagen salt precipitation device structure is relatively simple. When adding collagen to a high-salt concentration solution, most of the addition is fixed-point addition. The viscosity of collagen is strong, and the addition process is prone to stacking and covering, which reduces the contact area of part of the collagen with the solution, or even cannot contact, resulting in a significant reduction in salt precipitation effect. Therefore, we propose a collagen salt precipitation device. UTILITY MODEL CONTENT
[0004] The utility model discloses a kind of collagen salt precipitation devices to solve the shortcomings in prior art. The common collagen salt precipitation device structure is relatively simple. When adding collagen to a high-salt concentration solution, most of the addition is fixed-point addition. The viscosity of collagen is strong, and the addition process is prone to stacking and covering, which reduces the contact area of part of the collagen with the solution, or even cannot contact, resulting in a significant reduction in salt precipitation effect.
[0005] To achieve the above object, the utility model adopts the following technical scheme:
[0006] A kind of collagen salt precipitation device, including barrel body, the top of the barrel body is threadedly connected with barrel cover;
[0007] The inner bottom of the barrel body is rotatably connected with fixed block, the top of the fixed block is provided with cross slot, the periphery of the fixed block is welded with a plurality of stirring frames;
[0008] The inside of the barrel cover is provided with built-in groove, the inside of the built-in groove is installed with drive assembly, the top of the barrel cover is provided with injection port, the periphery of the injection port extending to one end of built-in groove is provided with conveying pipeline, the periphery of the conveying pipeline penetrating the bottom of barrel cover one end is welded with a plurality of branch pipes, the one end of the conveying pipeline penetrating the bottom of barrel cover is welded with connecting rod.
[0009] As the preferred scheme of the utility model, the bottom of the barrel body is bonded with an anti-skid pad.
[0010] The technical effect of the further scheme is that the anti-skid pad can improve the friction between the barrel body and the table top, prevent the barrel body from sliding during use, and improve the use stability.
[0011] As the preferred scheme of the utility model, the driving assembly comprises a motor, the motor is fixedly installed inside the built-in groove, the output end of the motor is fixedly connected with a driving gear, the right side of the driving gear and the periphery of the conveying pipeline are engagedly connected with a driven gear, and the driven gear is welded with the conveying pipeline.
[0012] The technical effect of the further scheme is that the rotation of the motor can drive the driving gear to rotate, the driving gear drives the conveying pipeline to rotate through the driven gear, the movement and conveying of the collagen are realized, the superposition and covering phenomenon is prevented, and the salting-out effect is improved.
[0013] As the preferred scheme of the utility model, a plurality of leakage holes are equidistantly arranged at the bottom of the branch pipe.
[0014] The technical effect of the further scheme is that the use of the plurality of leakage holes at the bottom of the branch pipe can realize the multi-point conveying of the collagen, and further improve the salting-out effect.
[0015] As the preferred scheme of the utility model, one end of the connecting rod close to the bottom is cross-shaped and is inserted into the inside of the cross-shaped clamping groove.
[0016] The technical effect of the further scheme is that the insertion of the connecting rod into the inside of the cross-shaped clamping groove can connect the conveying pipeline and the fixing block, so that the fixing block is driven to rotate together when the conveying pipeline rotates, the high-salt-concentration solution and the collagen are stirred, the salting-out effect is improved.
[0017] As the preferred scheme of the utility model, the material injection port, the conveying pipeline, the leakage hole and the barrel body are communicated.
[0018] The technical effect of the further scheme is that the collagen is injected into the inside of the conveying pipeline through the material injection port by the external feeding device, flows through the conveying pipeline into the branch pipe, flows out through the leakage hole into the inside of the barrel body, and is mixed with the high-salt-concentration solution stored in the inside of the barrel body to realize salting-out.
[0019] Compared with the prior art, the utility model has the beneficial effects that:
[0020] The utility model discloses a kind of collagen salt dissociation devices, including barrel body and barrel cover, barrel body is provided with fixed block, cross slot, stirring frame, antiskid pad, barrel cover is provided with built-in recess, drive assembly, injection port, conveying pipeline, branch pipe, connecting rod, it is characterized by the following: fixed block is arranged on the barrel body, and cross slot is arranged on the fixed block, and stirring frame is arranged on the cross slot, and antiskid pad is arranged on the stirring frame, and built-in recess is arranged on the barrel cover, and drive assembly is arranged in built-in recess, and injection port is arranged on the barrel cover, and conveying pipeline is arranged in barrel body, and branch pipe is arranged in conveying pipeline, and connecting rod is arranged on the stirring frame. BRIEF DESCRIPTION OF DRAWINGS
[0021] Fig. 1 It is an overall structure schematic diagram of the utility model provides a kind of collagen salt dissociation device;
[0022] Fig. 2 It is the overall front structure dissection of the utility model provides a kind of collagen salt dissociation device;
[0023] Fig. 3 It is the barrel body top end structure dissection of the utility model provides a kind of collagen salt dissociation device.
[0024] Legend: 1, barrel body;101, fixed block;102, cross slot;103, stirring frame;104, antiskid pad;2, barrel cover;201, built-in recess;202, drive assembly;2021, motor;2022, drive gear;2023, driven gear;203, injection port;204, conveying pipeline;205, branch pipe;2051, leakage hole;206, connecting rod. DETAILED DESCRIPTION
[0025] The technical scheme in the embodiments of the utility model will be described clearly and completely in conjunction with the embodiments of the utility model, apparently, the described embodiments are only part of the embodiments of the utility model, not all the embodiments, based on the embodiments in the utility model, all other embodiments obtained by the person skilled in the art without doing creative work belong to the range of protection of the utility model.
[0026] In order to facilitate understanding of the utility model, the utility model will be described more fully with reference to relevant, given several embodiments of the utility model, however, the utility model can be realized in many different forms, and is not limited to the embodiments described in this paper, on the contrary, the purpose of providing these embodiments is to make the disclosure of the utility model more thorough and comprehensive.
[0027] It should be noted that when an element is referred to as being "on" another element, it can be directly on the other element or intervening elements can also be present; when an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements can also be present. As used herein, the terms "vertical", "horizontal", "left", "right", and the like are used for explanation purposes only and are not intended to limit the scope of the present application.
[0028] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used in the description of the application herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application. As used herein, the term "and / or" includes any and all combinations of one or more of the associated listed items.
[0029] Embodiment 1
[0030] As shown in Figs. 1-3 The utility model provides a kind of collagen salt dialysis device, including bucket body 1, the top end of bucket body 1 is threadedly connected with bucket cover 2, the inner bottom of bucket body 1 is rotatably connected with fixed block 101, the top end of fixed block 101 is equipped with cross slot 102, a plurality of stirring frame 103 are welded around the periphery of fixed block 101, built-in recess 201 is equipped in the inside of bucket cover 2, driving assembly 202 is installed in the inside of built-in recess 201, injection port 203 is equipped in the top end of bucket cover 2, injection port 203 extends to the periphery of one end of built-in recess 201 and is equipped with conveying pipeline 204, a plurality of branch pipes 205 are welded around the periphery of conveying pipeline 204 and penetrate the bottom of bucket cover 2 one end, connecting rod 206 is welded to the one end of conveying pipeline 204 and penetrates the bottom of bucket cover 2.
[0031] Embodiment 2
[0032] As shown in Figs. 1-3As shown, the bottom of the barrel body 1 is bonded with a non-slip pad 104, the friction between the barrel body 1 and the table top can be improved through the non-slip pad 104, the barrel body 1 is prevented from sliding during use, the use stability is improved, the driving assembly 202 comprises a motor 2021, the motor 2021 is fixedly installed inside the built-in groove 201, the output end of the motor 2021 is fixedly connected with a driving gear 2022, a driven gear 2023 is engagedly connected to the right side of the driving gear 2022 and the periphery of the conveying pipeline 204, the driven gear 2023 is welded with the conveying pipeline 204, the driving gear 2022 can be driven to rotate through the rotation of the motor 2021, the conveying pipeline 204 is driven to rotate through the driven gear 2023, so that the movement and conveying of the collagen are realized, the superposition and covering phenomenon is prevented, the salting-out effect is improved, a plurality of leakage holes 2051 are equidistantly formed in the bottom of the branch pipe 205, the collagen can be multi-point conveyed through the use of the plurality of leakage holes 2051 in the bottom of the branch pipe 205, and the salting-out effect is further improved, one end of the connecting rod 206 close to the bottom is cruciform and is inserted into the inside of the cross-shaped clamping groove 102, the connecting rod 206 is inserted into the inside of the cross-shaped clamping groove 102, the conveying pipeline 204 and the fixed block 101 are connected, so that the fixed block 101 is driven to rotate when the conveying pipeline 204 rotates, the high-salt-concentration solution and the collagen are stirred, the salting-out effect is improved, the material injection port 203, the conveying pipeline 204, the leakage hole 2051 and the barrel body 1 are communicated, the collagen is injected into the inside of the conveying pipeline 204 through the material injection port 203 by the external feeding device, flows through the conveying pipeline 204 into the branch pipe 205, and flows out through the leakage hole 2051 into the inside of the barrel body 1, and is combined with the high-salt-concentration solution stored in the inside of the barrel body 1 to perform salting-out.
[0033] The working process of the utility model: when a kind of collagen salting-out device is used for liquid collagen conveying, first, collagen is injected into the inside of conveying pipeline 204 through material injection port 203 by external feeding device, and flows through conveying pipeline 204 into branch pipe 205, then flows out through leakage hole 2051 into the inside of barrel body 1, and is combined with high-salt-concentration solution stored in the inside of barrel body 1 to perform salting-out, motor 2021 drives conveying pipeline 204 to rotate through driving gear 2022 and driven gear 2023 during the process, so that branch pipe 205 keeps the state of uniform speed rotation, collagen flowing out from leakage hole 2051 can be always in the state of multi-point movement and conveying, superposition and covering phenomenon is prevented, and under the action of connecting rod 206, stirring frame 103 also rotates, high-salt-concentration solution and collagen are stirred, the contact area of high-salt-concentration solution and collagen is further improved, and the salting-out effect is effectively improved.
[0034] Although the embodiments of the present application have been shown and described, it is to be understood that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present application, the scope of which is defined by the appended claims and their equivalents.
Claims
1. A collagen salt-analyzing device comprising a barrel (1), characterized in that: The top end of the barrel body (1) is threadedly connected with a barrel cover (2); The inner bottom of the barrel body (1) is rotationally connected with a fixing block (101), the top end of the fixing block (101) is provided with a cross-shaped clamping groove (102), and the outer periphery of the fixing block (101) is welded with a plurality of stirring frames (103); The barrel cover (2) is internally provided with an embedded groove (201), the embedded groove (201) is internally mounted with a driving assembly (202), the top end of the barrel cover (2) is provided with a material injection opening (203), the material injection opening (203) extends to the outer periphery of one end of the embedded groove (201) and is provided with a conveying pipeline (204), the conveying pipeline (204) penetrates through the outer periphery of one end of the bottom of the barrel cover (2) and is welded with a plurality of branch pipes (205), and the conveying pipeline (204) is welded with a connecting rod (206) at one end of the bottom of the barrel cover (2).
2. A collagen saltation device according to claim 1, characterized in that: The bottom of the barrel body (1) is bonded with an anti-skid pad (104).
3. The collagen saltation device of claim 1, wherein: The driving assembly (202) comprises a motor (2021), the motor (2021) is fixedly installed in the embedded groove (201), the output end of the motor (2021) is fixedly connected with a driving gear (2022), the right side of the driving gear (2022) and the outer periphery of the conveying pipeline (204) are engagedly connected with a driven gear (2023), and the driven gear (2023) is welded with the conveying pipeline (204).
4. The collagen saltation device of claim 1, wherein: The bottom of the branch pipe (205) is equidistantly provided with a plurality of leakage holes (2051).
5. The collagen saltation device of claim 1, wherein: The end close to the bottom of the connecting rod (206) is cross-shaped and is inserted into the cross-shaped clamping groove (102).
6. The collagen saltation device of claim 1, wherein: The material injection opening (203), the conveying pipeline (204), the leakage hole (2051) and the barrel body (1) are in communication.