Online cleaning device for spray needle of liquid chromatograph-mass spectrometer

By designing an online cleaning device for the nozzles of a liquid chromatography-mass spectrometry (LC-MS) instrument, and utilizing a motor-driven gear meshing transmission to rotate the brush bristles, the problem of incomplete nozzle cleaning was solved, achieving thorough removal of impurities from the nozzle surface and improving the cleaning effect.

CN223602926UActive Publication Date: 2025-11-28SHANGHAI RUOTUO BIOSCIENCES CO LTD
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Patent Information

Application Number
CN202422558143.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-10-23
Publication Date
2025-11-28
Estimated Expiration
2034-10-23

AI Technical Summary

Technical Problem

The existing nozzle cleaning device for liquid chromatography-mass spectrometry (LC-MS) instruments has the problem of incomplete cleaning, with impurities still remaining on the nozzle surface.

Method used

An online cleaning device for the nozzles of a liquid chromatography-mass spectrometry (LC-MS) instrument was designed. The device uses a motor-driven gear meshing transmission to rotate the brush bristles on the shaft. Through the cooperation of the gear and rack, the nozzles are thoroughly cleaned.

Benefits of technology

The cleaning effect of the spray needles has been improved, making the surface of the spray needles cleaner and the cleaning more thorough, thus enhancing the practicality of the device.

✦ Generated by Eureka AI based on patent content.

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Abstract

The spray needle online cleaning device comprises a machine body, two through openings are symmetrically formed in the inner side wall of the machine body, moving blocks are installed in the two through openings, one side of the surface of one moving block is rotationally connected with a gear, and the other side of the surface of the other moving block is rotationally connected with a rotating shaft. A rack is fixedly connected to the surface, close to the gear, of the machine body, the gear is in meshed connection with the rack, a driving assembly is arranged on one side of the surface of the machine body, and a vertical plate is fixedly connected to the surface, away from the gear, of one moving block. By means of the structure, the motor is used for driving the gear to be in meshing transmission on the rack and driving the bristles outside the rotating shaft to rotate, a plurality of spray needle bodies can be brushed conveniently, the contact area of the spray needles during washing is increased, the spray needles are cleaned more thoroughly, a small amount of impurities on the surfaces of the spray needles are avoided, and the service life of the spray needles is prolonged. And the cleaned spray needle is cleaner, and the practicability is higher.
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Description

TECHNICAL FIELD

[0001] The utility model relates to spray needle cleaning technical field, in particular to a kind of spray needle online cleaning device of liquid quality combination appearance. BACKGROUND

[0002] Liquid quality combination appearance is mainly applied to drug metabolism and pharmacokinetics research, clinical pharmacology research, natural medicine development research, newborn screening, protein and peptide identification, residual analysis, toxic analysis, environmental analysis, environmental protection, food, tap water, health and epidemic prevention etc.

[0003] In prior art, spray needle online cleaning device of liquid quality combination appearance has some defects, most can only use water stirring to flush spray needle, due to the amplitude of stirring is small, the contact rate angle in the process of spray needle flushing, leading to spray needle cleaning is not thorough, still contain a small amount of impurities adhering to the surface of spray needle, in order to solve this problem, therefore a kind of spray needle online cleaning device of liquid quality combination appearance is presented. UTILITY MODEL CONTENT

[0004] The utility model solves the technical problems that most can only use water stirring to flush spray needle, due to the amplitude of stirring is small, the contact rate angle in the process of spray needle flushing, leading to spray needle cleaning is not thorough, still contain a small amount of impurities adhering to the surface of spray needle.

[0005] To solve the above technical problems, one technical scheme of the utility model is provided: provide a kind of spray needle online cleaning device of liquid quality combination appearance, including body, the inside wall of body is symmetrically provided with two through ports, the inside of two the through port is all installed with moving block, the surface one side of one of the moving block is rotatably connected with gear, the surface of the body close to gear is fixedly connected with rack, and gear and rack are engagedly connected, the surface one side of the body is provided with drive assembly, the surface of one of the moving block away from gear is fixedly connected with vertical plate, the surface of vertical plate is rotatably connected with first driven wheel, the surface of vertical plate away from first driven wheel is rotatably connected with shaft with the inside wall of body, the outer surface of shaft is fixedly connected with multiple bristles, the outer portion of shaft is fixedly connected with second driven wheel;

[0006] The outer sleeve of the first driven wheel and the second driven wheel is provided with a belt, the inner bottom of the machine body is provided with a water tank, the inside of the machine body is provided with a bearing plate, a plurality of mounting holes are formed in the surface of the bearing plate, a plurality of spray needle bodies for the liquid chromatograph-mass spectrometer are mounted in the mounting holes, the top of the bearing plate is fixedly connected with two connecting plates, the top of the two connecting plates is fixedly connected with a top plate, the surface of the machine body is rotatably connected with two protection doors, and visible windows are embeddedly mounted on the surface of the two protection doors.

[0007] Preferably, a sliding groove is formed in the surface of the machine body close to the gear, a sliding block is mounted in the sliding groove, a fixed plate is fixedly connected to one side of the surface of the sliding block, and a motor is fixedly connected to the surface of the fixed plate.

[0008] Preferably, the outer surface of the sliding block is slidably connected with the inner side wall of the sliding groove, and the sliding block and the sliding groove are both T-shaped.

[0009] Preferably, the top of the machine body is fixedly connected with an electric push rod, the output end of the electric push rod extends through the inside of the machine body and is fixedly connected with the top of the top plate, the electric push rod can drive the top plate to move, and the operation is more convenient.

[0010] Preferably, a clamping plate is rotatably connected to the surface of the machine body close to the protection door, and the surface of the clamping plate is clampedly connected with the surface of the protection door.

[0011] Preferably, a plurality of supporting legs are fixedly connected to the bottom of the machine body, the machine body is supported by the plurality of supporting legs, and stable placement is ensured.

[0012] Preferably, a water inlet valve and a water outlet valve are fixedly installed on one side of the surface of the machine body, the water inlet valve and the water outlet valve are used for water injection and drainage, and the operation is very convenient.

[0013] The machine body has the following beneficial effects:

[0014] The machine body has the following beneficial effects: BRIEF DESCRIPTION OF DRAWINGS

[0015] Figure 1 is a first perspective view of the spray needle online cleaning device of the liquid mass spectrometer;

[0016] Figure 2 is a second perspective view of the spray needle online cleaning device of the liquid mass spectrometer;

[0017] Figure 3 is a first perspective view of the spray needle online cleaning device of the liquid mass spectrometer; Figure 1 is an enlarged view of part A in the figure.

[0018] In the figure: 1, support leg; 2, motor; 3, fixed plate; 4, machine body; 5, bearing plate; 6, protection door; 7, spray needle body; 8, visible window; 9, clamping plate; 10, brush; 11, rack; 12, gear; 13, electric push rod; 14, moving block; 15, top plate; 16, connecting plate; 17, through port; 18, first driven wheel; 19, belt; 20, second driven wheel; 21, rotating shaft; 22, sliding block; 23, sliding groove. DETAILED DESCRIPTION

[0019] The preferred embodiments of the utility model are described in detail below in combination with the drawings, so that the advantages and features of the utility model can be more easily understood by those skilled in the art, and the protection scope of the utility model can be more clearly and explicitly defined.

[0020] Please refer to Figures 1 to 3 A spray needle online cleaning device of a liquid mass spectrometer, comprising a machine body 4, two through ports 17 are symmetrically formed in the inner side wall of the machine body 4, moving blocks 14 are mounted in the interiors of the two through ports 17, the moving blocks 14 are convenient to move in the interiors of the through ports 17, the surface of one of the moving blocks 14 is rotatably connected with a gear 12, a rack 11 is fixedly connected to the surface of the machine body 4 close to the gear 12, and the gear 12 and the rack 11 are meshingly connected, the rotation of the gear 12 can be meshingly transmitted on the rack 11, a driving assembly is arranged on one side of the surface of the machine body 4, a vertical plate is fixedly connected to the surface of the moving block 14 away from the gear 12, a first driven wheel 18 is rotatably connected to the surface of the vertical plate, a rotating shaft 21 is rotatably connected to the inner side wall of the machine body 4 away from the first driven wheel 18 on the surface of the vertical plate, a plurality of brushes 10 are fixedly connected to the outer surface of the rotating shaft 21, and a second driven wheel 20 is fixedly connected to the outside of the rotating shaft 21;

[0021] The outer sleeve of the first driven wheel 18 and the second driven wheel 20 is provided with a belt 19, and the first driven wheel 18 and the second driven wheel 20 can drive the rotating shaft 21 to rotate the brush 10 by cooperating with the belt 19, which is very convenient. The inner bottom of the machine body 4 is provided with a water tank, and the inside of the machine body 4 is provided with a bearing plate 5. A plurality of mounting holes are formed in the surface of the bearing plate 5, and a plurality of mounting holes are provided with a spray needle body 7 for a liquid chromatograph. The spray needle body 7 is convenient to install. The top of the bearing plate 5 is fixedly connected with two connecting plates 16, and the top of the two connecting plates 16 is fixedly connected with a top plate 15. The surface of the machine body 4 is rotatably connected with two protective doors 6 on both sides, and the surface of the two protective doors 6 is embedded with a visual window 8. The visual window 8 is convenient for observing the internal use, and the surface of the machine body 4 close to the protective door 6 is rotatably connected with a clamping plate 9, and the surface of the clamping plate 9 is tightly connected with the surface of the protective door 6. The rotation of the clamping plate 9 is convenient for locking the protective door 6. The bottom of the machine body 4 is fixedly connected with a plurality of supporting legs 1, which are supported by the plurality of supporting legs 1 to ensure stable placement. The surface of the machine body 4 is fixedly connected with a water inlet valve and a water outlet valve on one side. The water inlet valve and the water outlet valve are convenient for water injection and drainage, which is very convenient.

[0022] As shown in Figure 2 and Figure 3 The surface of the machine body 4 close to the gear 12 is provided with a sliding groove 23, and the sliding groove 23 is provided with a sliding block 22. The surface of the sliding block 22 is fixedly connected with a fixed plate 3, and the surface of the fixed plate 3 is fixedly connected with a motor 2. The output end of the motor 2 extends through the fixed plate 3 and is fixedly connected with the surface of the gear 12. The gear 12 is driven to rotate by the motor 2, and the gear 12 is engaged with the rack 11 to move conveniently. The outer surface of the sliding block 22 is slidably connected with the inner side wall of the sliding groove 23. The sliding block 22 and the sliding groove 23 are both T-shaped. The outer surface of the two moving blocks 14 is slidably connected with the inner side wall of the two through holes 17. The top of the machine body 4 is fixedly connected with an electric push rod 13. The output end of the electric push rod 13 extends through the machine body 4 and is fixedly connected with the top of the top plate 15. The electric push rod 13 can drive the top plate 15 to move, which is convenient to operate.

[0023] The utility model discloses a rotatory cardboard 9 is convenient for opening the protective door 6 in utilization, installs the spray needle body 7 in the mounting hole inside the surface of bearing plate 5, opens the electric push rod 13 after finishing, and electric push rod 13 drives the roof 15 to remove, and the roof 15 removes can drive the connecting plate 16 to remove, and the connecting plate 16 removes when can push bearing plate 5 and drive the spray needle body 7 to remove, opens the water inlet valve and can inject water, make keep the water source of sufficient amount, open motor 2, and motor 2 drive gear 12 to rotate on the rack 11 meshing removal, and utilize the slider 22 in the inside sliding of the sliding slot 23 to improve the removal stability, and gear 12 removes the moving block 14 in the inside removal of the through -opening 17 under the cooperation of first driven wheel 18 and second driven wheel 20 belt 19 can drive the rotation of the shaft 21, make will brush the hair 10 rotate to the brush washing of multiple spray needle body 7, improve the contact area when the spray needle body 7 washes, make the process of spray needle body 7 cleaning be more thorough, avoid the surface of spray needle body 7 to exist a few impurities, and the spray needle body 7 after cleaning is cleaner, and the practicality is stronger.

[0024] The above-mentioned is only the embodiment of the utility model, and does not limit the patent range of the utility model, and the equivalent structure or equivalent flow conversion of the contents of the utility model specification and drawings, or direct or indirect application in other related technical fields, are all included in the patent protection range of the utility model.

Claims

1. A device for on-line cleaning of a spray needle of a liquid chromatograph-mass spectrometer, comprising a body (4), characterized in that: The inner side wall of the body (4) is symmetrically provided with two through openings (17), the interiors of the two through openings (17) are both provided with moving blocks (14), one side of the surface of one of the moving blocks (14) is rotatably connected with a gear (12), the surface of the body (4) close to the gear (12) is fixedly connected with a rack (11), and the gear (12) and the rack (11) are in meshing connection, one side of the surface of the body (4) is provided with a driving assembly, the surface of the moving block (14) away from the gear (12) is fixedly connected with a vertical plate, the surface of the vertical plate is rotatably connected with a first driven wheel (18), the surface of the vertical plate away from the first driven wheel (18) is rotatably connected with a rotating shaft (21) with the inner side wall of the body (4), the outer surface of the rotating shaft (21) is fixedly connected with a plurality of bristles (10), and the outer portion of the rotating shaft (21) is fixedly connected with a second driven wheel (20). The outer portions of the first driven wheel (18) and the second driven wheel (20) are provided with a belt (19), the inner bottom of the body (4) is provided with a water tank, the interior of the body (4) is provided with a bearing plate (5), the surface of the bearing plate (5) is provided with a plurality of mounting holes, the interiors of the plurality of mounting holes are provided with spray needle bodies (7) for liquid chromatography-mass spectrometry instruments, the top of the bearing plate (5) is fixedly connected with two connecting plates (16), the tops of the two connecting plates (16) are fixedly connected with a top plate (15), the surfaces of the two sides of the body (4) are rotatably connected with two protective doors (6), and the surfaces of the two protective doors (6) are inlaidly provided with visual windows (8). 2.The on-line cleaning device for a spray needle of a liquid chromatograph-mass spectrometer according to claim 1, characterized in that: The surface of the body (4) close to the gear (12) is provided with a sliding groove (23), the interior of the sliding groove (23) is provided with a sliding block (22), one side of the surface of the sliding block (22) is fixedly connected with a fixed plate (3), the surface of the fixed plate (3) is fixedly connected with a motor (2), and the output end of the motor (2) extends to the surface of the fixed plate (3) and the gear (12) and is fixedly connected therewith. 3.The on-line cleaning device for a spray needle of a liquid chromatograph-mass spectrometer according to claim 2, characterized in that: The outer surface of the sliding block (22) is in sliding connection with the inner side wall of the sliding groove (23), and the sliding block (22) and the sliding groove (23) are both provided in a T shape, and the outer surfaces of the two moving blocks (14) are in sliding connection with the inner side walls of the two through openings (17).

4. The online cleaning device for the spray needle of a liquid chromatograph-mass spectrometer according to claim 1, characterized in that: The top of the body (4) is fixedly connected with an electric push rod (13), the output end of the electric push rod (13) extends to the interior of the body (4) and is fixedly connected with the top of the top plate (15).

5. The online cleaning device for the spray needle of a liquid chromatograph-mass spectrometer according to claim 1, characterized in that: The surface of the body (4) close to the protective door (6) is rotatably connected with a clamping plate (9), and the surface of the clamping plate (9) is clampedly connected with the surface of the protective door (6).

6. The online cleaning device for electrospray needle of liquid chromatograph-mass spectrometer according to claim 1, characterized in that: The bottom of the body (4) is fixedly connected with a plurality of supporting legs (1).

7. The online cleaning device for electrospray needle of liquid chromatograph-mass spectrometer according to claim 1, characterized in that: The surface of the body (4) is fixedly provided with a water inlet valve and a water outlet valve.