Composite cosmetic allergen patch test device with multi-layer structure

Abstract

The utility model relates to the field of cosmetic allergy detection. A composite cosmetic allergen patch test device with a multi-layer structure comprises a covering layer, a middle layer, a base layer and a backing layer, the covering layer, the middle layer and the base layer are all of a sheet structure, a groove with a rectangular cross section is formed in the lower portion of the middle of the covering layer 1, and the backing layer is arranged in the groove. The middle layer is located in the groove, the upper surface of the middle layer is fixed to the upper surface of the groove of the covering layer, the upper surface of the base layer is fixed to the lower surface of the middle layer, projections of the middle layer and the base layer on the covering layer coincide and are located in the groove of the covering layer, and a rubber ring is arranged on the edge of the lower surface of the covering layer. The covering layer is fixed on the backing layer through a rubber ring, the lower surface of the base layer protrudes out of the lower surface of the covering layer by 1-2mm, and in the using process, the covering layer is fixed on the inner side of a forearm through the rubber ring.

Description

Technical Field

[0001] This utility model relates to the field of cosmetic allergy detection. Background Technology

[0002] Cosmetic allergies are immune or irritant reactions triggered by skin contact with cosmetics. Symptoms (graded by severity): Mild allergies present with localized erythema, swelling, and itching, accompanied by red papules or small blisters; Moderate allergies may lead to erosion, ulceration, and crusting due to scratching or improper treatment, potentially resulting in secondary infection; Severe allergies, with long-term and recurrent allergies, can develop into chronic dermatitis, manifesting as rough skin, pigmentation, or scarring, and in extremely rare cases, anaphylactic shock (difficulty breathing, sudden drop in blood pressure, etc.) may occur. Therefore, allergy testing is necessary for new cosmetics.

[0003] Patch testing, as a targeted allergen detection method, has advantages such as being non-invasive, safe, and capable of simultaneously detecting multiple allergens. Chinese patents titled "A Far-Infrared Skin Cosmetic Allergy Test Patch" (patent number 201220175471.2) and "A Method for Detecting Cosmetic Allergens and an Allergen Patch Reagent Kit" (patent number 202110393608.5) both use traditional patch testing devices. However, traditional patch testing devices, due to their flat and uniform shape, are often only used on flat skin areas such as the back. This results in limited sensitivity in the test area, leading to long testing cycles, and the application area is often covered by clothing, making testing inconvenient. Traditional patch testing materials lack zoned testing areas, allowing only one cosmetic sample to be tested simultaneously; different cosmetic samples cannot be tested concurrently. Utility Model Content

[0004] The technical problem to be solved by this utility model is: how to solve the problem that existing patch tests can only perform single cosmetic sample testing when detecting allergens, and the effect detection speed is slow.

[0005] The technical solution adopted in this utility model is: a composite cosmetic allergen patch testing device with a multi-layer structure, including a cover layer, an intermediate layer, a base layer, and a backing layer. The cover layer, intermediate layer, and base layer are all sheet structures (the backing layer is not required and can also be a sheet structure). The sheet structure refers to a sheet-like material with a thickness of less than 10 mm. The lower surface of the cover layer has a rectangular groove in the middle. The intermediate layer is located in the groove and its upper surface is fixed to the upper surface of the groove of the cover layer. The upper surface of the base layer is fixed to the lower surface of the intermediate layer. The projections of the intermediate layer and the base layer on the cover layer coincide and are located in the groove of the cover layer. There is an adhesive ring (a ring-shaped structure formed by adhesive) at the edge of the lower surface of the cover layer (outside the groove). During storage, the cover layer is fixed to the backing layer by the adhesive ring. The lower surface of the base layer protrudes 1-2 mm beyond the lower surface of the cover layer. During use, the cover layer is fixed to the inside of the forearm by the adhesive ring.

[0006] The base layer comprises a grid of horizontal and vertically intersecting strips made of a hydrophobic material and square grids filled with a hydrophilic material in the center of each grid. Each square grid has a circular embossing in its center. The base layer is flush with the top and bottom surfaces except for the embossed area (the grid strips separate each square grid, and the thickness of the grid strips is equal to the thickness of the square grid), and the embossed area is slightly concave.

[0007] The intermediate layer comprises a rectangular layer made of a hydrophobic material with multiple through-holes and a circular agent ring made of a hydrophilic material filling the through-holes. Each agent ring has a vent hole on its outer side. The upper and lower surfaces of the intermediate layer are flush, and the projection of the agent ring onto the base layer coincides with the embossing. "Flush" means that when the intermediate layer is placed horizontally, the upper surface and the lower surface of the intermediate layer are at the same horizontal level.

[0008] The beneficial effects of this utility model are: the utility model has a simple and ingenious structure and can detect multiple cosmetic samples at the same time. Different cosmetic samples are simply dropped into different reagent rings, and then the device of this utility model is removed from the backing layer and pasted on the inside of the forearm for quick and accurate detection. Attached Figure Description

[0009] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0010] Figure 2 This is a schematic diagram of the base layer of this utility model;

[0011] Figure 3 This is a schematic diagram of the intermediate layer of this utility model;

[0012] Figure 4 This is a schematic diagram of the covering layer of this utility model;

[0013] Among them, 1. Covering layer, 2. Intermediate layer, 3. Base layer, 4. Groove, 5. Adhesive ring, 6. Backing layer, 21. Through hole, 22. Agent ring, 23. Vent hole, 24. Rectangular layer, 31. Base grid, 32. Embossing, 33. Square base grid. Detailed Implementation

[0014] like Figure 1-4 As shown, the technical solution adopted by this utility model is: a composite cosmetic allergen patch test device with a multi-layer structure, including a cover layer 1, an intermediate layer 2, a base layer 3 and a backing layer 6.

[0015] The cover layer 1, intermediate layer 2, base layer 3 and backing layer 6 are all sheet structures. The sheet structure refers to a sheet with a thickness of less than 10 mm, and the length and width dimensions are greater than 5 times the thickness dimension.

[0016] The lower surface of the cover layer 1 has a rectangular groove 4 at its center. The depth of the groove 4 is the sum of the thicknesses of the intermediate layer 2 and the base layer 3 minus 1-2 mm. In one embodiment, the thicknesses of the intermediate layer 2 and the base layer 3 are both 3 mm, the thickness of the cover layer 1 is 7 mm, and the depth of the groove 4 is 5 mm. In one embodiment, the planar dimensions of the cover layer 1 are 6 cm * 8 cm, and the material of the cover layer 1 is an existing breathable and hypoallergenic adhesive tape. The planar dimensions of the groove 4 are 4 cm * 6 cm. The planar dimensions of the intermediate layer 2 and the base layer 3 are 4 cm * 6 cm, and their positional relationship is as follows... Figure 4 As shown.

[0017] The intermediate layer 2 is located in the groove and its upper surface is fixed to the upper surface of the groove 4 of the cover layer 1. The intermediate layer 2 includes a rectangular layer 24 made of hydrophobic material with multiple through holes 21 and a circular atomizing ring 22 made of hydrophilic material filling the through holes 21. In one embodiment, as shown... Figure 3 As shown, the rectangular layer 24 measures 3mm*4cm*6cm, and the outer radius of the reagent rings 22 is 0.8cm. The reagent rings 22 are arranged in an array, and each reagent ring 22 has a vent hole 23 on its outer side with a diameter of 0.5mm. The vent holes 23 are to ensure the air permeability of the test device, allowing the cosmetic sample to easily penetrate into the reagent rings 22. The upper surface of the groove 4 is fixed to the upper surface of the intermediate layer 2 with medical adhesive. The upper surface of the base layer 3 is fixed to the lower surface of the intermediate layer 2, and the two are also connected with medical adhesive.

[0018] The projections of the intermediate layer 2 and the base layer 3 onto the cover layer 1 coincide and are located within the groove 4 of the cover layer 1. An adhesive ring 5 is located at the edge of the lower surface of the cover layer 1. During storage, the cover layer 1 is fixed to the backing layer 6 by the adhesive ring 5. The lower surface of the base layer 3 protrudes 1 mm beyond the lower surface of the cover layer 1. During use, the cover layer 1 is fixed to the inner side of the forearm by the adhesive ring 5. The adhesive in the adhesive ring 5 is hypoallergenic medical adhesive.

[0019] The base layer 3 includes a grid of horizontal and vertically intersecting strips 31 made of hydrophobic material and square base cells 33 made of hydrophilic material that fill the gaps in the middle of the grid strips 31. Each square base cell 33 has a circular embossing 32 in the center. Except for the embossing 32, the upper and lower surfaces of the base layer 3 are flush, and the embossing 32 area is slightly concave.

[0020] In one embodiment, such as Figure 2 As shown, the base layer 3 includes a grid of horizontally and vertically intersecting strips 31 made of a hydrophobic material and square base cells 33 made of a hydrophilic material filling the gaps in the middle of the grid strips 31. The width of the grid strips 31 is 0.2 cm. The planar dimensions of the square base cells 33 are 2 cm * 2 cm. The imprint 32 is used to press out one or more concentric circles, which facilitates positioning by the tester. The sample is added to each test area near the center of the circle. The outer radius of the imprint 32 is 0.5-0.8 cm.

[0021] During use, first remove the backing layer 6, then drop the cosmetic sample to be tested onto the center of the imprint 32. The same or different cosmetic samples can be dropped onto each different imprint. Adhere the sample to the inner forearm. Remove the sample after 24-72 hours and observe the skin reaction for each different cosmetic sample. The skin reaction is used to determine if the patient is allergic to a specific cosmetic.

[0022] In one embodiment, the cosmetic is a hydrophilic cosmetic, and its composition may include, but is not limited to, hyaluronic acid, glycerin, propylene glycol, aloe vera extract, seaweed extract, and vitamin B5 (panthenol).

[0023] In one embodiment, the hydrophobic material is one or more of the following: polytetrafluoroethylene (PTFE) film, polydimethylsiloxane (PDMS) film, fluorinated ethylene propylene copolymer (FEP) film, polyethylene (PE) film, polypropylene (PP) film, and fluorocarbon coating. To maintain and enhance the hydrophobic properties of the material, appropriate modifications can be made. In one embodiment, the hydrophilic material portion is sodium alginate and gelatin, with a mass ratio of 1:1 to 1:3.

Claims

1. A composite cosmetic allergen patch testing device with a multi-layer structure, characterized in that: The material includes a cover layer (1), an intermediate layer (2), a base layer (3), and a backing layer (6). The cover layer (1), intermediate layer (2), and base layer (3) are all sheet structures. The lower surface of the cover layer (1) has a groove (4) with a rectangular cross-section in the middle. The intermediate layer (2) is located in the groove and its upper surface is fixed to the upper surface of the groove (4) of the cover layer (1). The upper surface of the base layer (3) is fixed to the lower surface of the intermediate layer (2). The projections of the intermediate layer (2) and the base layer (3) on the cover layer (1) coincide and are located in the groove (4) of the cover layer (1). There is a rubber ring (5) at the edge of the lower surface of the cover layer (1). During storage, the cover layer (1) is fixed to the backing layer (6) by the rubber ring (5). The lower surface of the base layer (3) protrudes 1-2 mm beyond the lower surface of the cover layer (1). During use, the cover layer (1) is fixed to the inside of the forearm by the rubber ring (5).

2. The composite cosmetic allergen patch testing device with a multi-layer structure according to claim 1, characterized in that: The base layer (3) includes a grid of horizontal and vertical interlacing made of hydrophobic material (31) and a square base grid (33) filled with hydrophilic material in the middle of the grid of the grid (31). Each square base grid (33) has a circular embossing (32) in the center.

3. The composite cosmetic allergen patch testing device with a multi-layer structure according to claim 2, characterized in that: The intermediate layer (2) includes a rectangular layer (24) made of hydrophobic material with multiple through holes (21) and a circular agent ring (22) made of hydrophilic material that fills the through holes (21). Each agent ring (22) has a vent hole (23) on its outer side. The upper and lower surfaces of the intermediate layer (2) are flush surfaces. The projection of the agent ring (22) on the base layer (3) coincides with the imprint (32). The flush surface means that when the intermediate layer (2) is placed horizontally, the upper surface of the intermediate layer (2) is at the same horizontal plane and the lower surface of the intermediate layer (2) is at the same horizontal plane.

Images