Glass microelectrode injection pump
By using a glass microelectrode injection pump, a glass capillary needle, and a micro-stepping motor, the shortcomings of existing micro-injection equipment in terms of high precision and stability are solved, achieving sub-nano-level drug delivery and simplified operation, improving the automation of the equipment and ease of use for beginners.
Patent Information
- Application Number
- CN202422564522.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-23
- Publication Date
- 2025-12-02
- Estimated Expiration
- 2034-10-23
AI Technical Summary
Existing micro-injection equipment has shortcomings in terms of high precision and stability, especially in nanoscale injection where the precision is not high, the degree of automation is low, the operation is complicated, the equipment stability is poor, and it is difficult for first-time users to master.
It employs a glass microelectrode injection pump, uses a glass capillary needle, combines a micro-stepping motor and a stainless steel fixing rod, is equipped with a display screen and control buttons, supports multiple working modes, integrates a displacement sensor and protective frame, has high precision and chemical corrosion resistance, and simplifies the operation process.
It achieves sub-nanometer-level drug delivery accuracy, simplifies operation procedures, enhances the automation level of the equipment and ease of use for beginners, and ensures the stability and safety of the equipment.
Smart Images
Figure CN223614970U_ABST
Abstract
Description
Technical Field
[0001] This application relates to the field of glass microelectrode injection pump technology, and more particularly to a glass microelectrode injection pump. Background Technology
[0002] Microinjection devices are widely used in fields such as biology and medicine, and are particularly crucial for the precise administration of small amounts of medication to experimental subjects in scientific research. While current microinjection devices on the market can achieve a certain degree of micro-injection, improvements are still needed in terms of high precision and stability, especially in nanometer-level injection volume control, where most devices struggle to meet high accuracy requirements. Furthermore, in practical use, some microinjection devices are quite complex to operate, increasing the workload of researchers and reducing work efficiency.
[0003] Most micro-injection devices on the market currently suffer from the following defects: First, the injection accuracy is not high, especially when injecting at the nano-level, deviations are prone to occur; second, the degree of automation is low, operation is relatively cumbersome, and frequent manual intervention is required; third, the stability and durability of the equipment are poor, and failures may occur during long-term continuous operation; fourth, the lack of a user-friendly interface design makes it difficult for first-time users to master the usage skills. Utility Model Content
[0004] To address the shortcomings of existing technologies, this application provides a glass microelectrode injection pump, which overcomes the deficiencies of existing technologies and aims to solve the following defects commonly found in most existing micro-injection devices: first, low injection accuracy, especially prone to deviation during nano-level injection; second, low degree of automation, cumbersome operation, requiring frequent manual intervention; third, poor stability and durability, potentially leading to malfunctions during long-term continuous operation; and fourth, lack of user-friendly interface design, making it difficult for first-time users to master the operating techniques.
[0005] To achieve the above objectives, this application provides the following technical solution: a glass microelectrode injection pump, comprising a pump head, an installation cavity inside the pump head, a liquid suction chamber and a micro-stepping motor installed inside the installation cavity, a needle installed at one end of the liquid suction chamber, the other end of the needle extending through one side of the pump head to the outside, a screw installed at the output end of the micro-stepping motor, a piston installed inside the liquid suction chamber, a connecting sleeve installed outside the screw, a fixing rod fixedly connected to one side of the connecting sleeve, a piston fixedly connected to the other end of the fixing rod, a connection port installed at one end of the pump head, a control console fixedly installed at the other end of the connection port, a display screen and multiple sets of control buttons provided outside the control console, and an electrical connection between the control console and the micro-stepping motor.
[0006] By adopting the above technical solution and setting up a control console, the needle is made of glass capillary with an ultra-fine diameter to reduce damage to biological tissues. The screw and fixed rod inside the pump head work together to ensure micron-level motion control precision. The total stroke of the fixed rod reaches 25.40mm, ensuring sufficient injection range. The pump head is equipped with a micro-stepping motor, which can achieve a minimum volume resolution of 0.01nL. The control console integrates a display screen and control buttons, which can support switching between multiple working modes, including starting point positioning, emptying, sampling, programming, and simultaneous injection in groups. The injection volume, injection rate and other parameters can be easily set through the display screen, and the injection status can be monitored in real time. When the injection program is started, the micro-stepping motor drives the fixed rod to move forward or backward along the screw, thereby realizing the suction or discharge of liquid by the needle, achieving higher injection precision, supporting sub-nano-level drug delivery, significantly improving the accuracy of micro-injection, and greatly simplifying the operation process. The intuitive and convenient touch screen design allows even beginners to quickly master the basic operation of the equipment.
[0007] As a preferred technical solution of this application, a wire is provided on one side of the console, and a controller is installed at the other end of the wire. The controller has two sets of mounting slots inside, and a pedal is installed inside each of the two sets of mounting slots. A spring is provided at the bottom of each of the two sets of pedals, and one end of each set of pedals is hinged to the controller.
[0008] By adopting the above technical solution and setting up the wiring, it is more convenient for staff to operate the pump head during use, and the operation process can be greatly simplified. Parameters can also be adjusted during the injection process, effectively improving the practicality of the device.
[0009] As a preferred technical solution of this application, the micro-stepping motor is an ultra-precision motor from Panasonic Corporation of Japan, the fixing rod is made of stainless steel, and the needle is a glass capillary.
[0010] By adopting the above technical solution, and by setting the micro-stepping motor to be an ultra-precision motor from Panasonic Corporation of Japan, it has extremely high positioning accuracy. The fixing rod is made of stainless steel with a finely ground surface, and the needle is a glass capillary, ensuring injection accuracy while also having strong resistance to chemical corrosion.
[0011] As a preferred technical solution of this application, the micro-stepping motor is externally equipped with a protective frame, and the connecting sleeve is made of silent sponge material.
[0012] By adopting the above technical solution and setting a screw, vibration reduction and noise insulation can be achieved for the micro-stepping motor during operation, minimizing interference with staff and improving safety.
[0013] As a preferred embodiment of this application, a displacement sensor is sleeved on the outside of the fixed rod, and the displacement sensor is electrically connected to the control console.
[0014] By adopting the above technical solution and setting a displacement sensor, the movement length of the fixed rod can be measured more accurately during use, thereby achieving precise control over the extraction of the drug by the needle.
[0015] As a preferred technical solution of this application, a switch and an indicator light are installed on the outside of the pump head, and both the switch and the indicator light are electrically connected to the control console.
[0016] By adopting the above technical solution and setting up a switch, it is easier for operators to control the pump head. The indicator lights can indicate the current working status of the pump head in a timely manner, thus improving the practicality of the device.
[0017] As a preferred technical solution of this application, the pump head is equipped with multiple sets of counterweights.
[0018] By adopting the above technical solution and setting a counterweight, the balance of the pump head can be improved during use, preventing the pump head from shifting due to an unstable center of gravity during use or placement.
[0019] As a preferred technical solution of this application, the pump head is fitted with an anti-slip sleeve, and the surfaces of both sets of pedals are provided with an anti-slip layer.
[0020] By adopting the above technical solution and setting anti-slip sleeves and anti-slip layers, the device can effectively prevent slipping during use and improve its operational stability.
[0021] The beneficial effects of this application are:
[0022] 1. By setting up a control console, the needle is made of glass capillary with an ultra-fine diameter to reduce damage to biological tissues. The internal screw and fixing rod of the pump head work together to ensure micron-level motion control precision. The total stroke of the fixing rod is 25.40mm, ensuring sufficient injection range. The pump head is equipped with a micro-stepping motor, which can achieve a minimum volume resolution of 0.01nL. The external control console integrates a display screen and control buttons, which can support switching between multiple working modes, including starting point return, emptying, sampling, programming, and grouping simultaneous injection. The injection volume can be easily set through the display screen.
[0023] 2. By setting up wiring, it is easier for staff to operate the pump head during use, and the operation process can be greatly simplified. Parameters can also be adjusted during injection, effectively improving the practicality of the device. Attached Figure Description
[0024] Figure 1 This is a schematic diagram of the overall structure of this application;
[0025] Figure 2 This is a cross-sectional structural diagram of this application;
[0026] Figure 3 This is a schematic diagram of the console structure of this application;
[0027] Figure 4 This is a schematic diagram of the controller structure of this application.
[0028] In the diagram: 1. Pump head; 101. Mounting cavity; 102. Indicator light; 103. Anti-slip sleeve; 104. Switch; 105. Counterweight; 106. Connecting port; 2. Needle; 3. Suction chamber; 301. Piston; 303. Limiting ring; 4. Micro stepper motor; 401. Screw; 402. Connecting sleeve; 403. Fixing rod; 405. Displacement sensor; 406. Protective frame; 5. Control console; 501. Display screen; 502. Control button; 503. Wire; 6. Controller; 601. Mounting slot; 602. Pedal; 603. Spring; 604. Anti-slip layer. Detailed Implementation
[0029] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of this application.
[0030] Reference Figure 1-3A glass microelectrode injection pump includes a pump head 1. The pump head 1 has an internal mounting cavity 101, inside which a suction chamber 3 and a micro-stepping motor 4 are installed. A needle 2 is installed at one end of the suction chamber 3, and the other end of the needle 2 extends through one side of the pump head 1 to the outside. A screw 401 is installed at the output end of the micro-stepping motor 4. A piston 301 is installed inside the suction chamber 3. A connecting sleeve 402 is installed outside the screw 401. A fixing rod 403 is fixedly connected to one side of the connecting sleeve 402, and the piston 301 is fixedly connected to the other end of the fixing rod 403. A connection port 106 is installed at one end of the pump head 1, and a control console 5 is fixedly installed at the other end of the connection port 106. The control console 5 has a display screen 501 and multiple control buttons 502 on its exterior. The control console 5 is electrically connected to the micro-stepping motor 4. The micro-stepping motor 4 is an ultra-precision motor from Panasonic Corporation of Japan. The fixing rod 403 is made of stainless steel; the needle 2 is a glass capillary.
[0031] By configuring the control console 5, during use, the needle 2 is made of glass capillary with an ultra-fine diameter to reduce damage to biological tissues. The screw 401 and the fixing rod 403 inside the pump head 1 work together to ensure micron-level motion control precision. The total stroke of the fixing rod 403 reaches 25.40 mm, ensuring sufficient injection range. The pump head 1 is equipped with a micro-stepping motor 4, which can achieve a minimum volume resolution of 0.01 nL. The control console 5 integrates a display screen 501 and control buttons 502, which can support switching between multiple working modes, including start point return. Simultaneous injection, including positioning, emptying, sampling, programming, and grouping, can be easily set via the display screen 501, allowing for easy setting of parameters such as injection volume and injection rate, and real-time monitoring of the injection process. When the injection program is started, the micro-stepping motor 4 drives the fixed rod 403 forward or backward along the screw 401, thereby achieving the suction or discharge of liquid by the needle 2, achieving higher injection accuracy, supporting sub-nano-level drug delivery, significantly improving the accuracy of micro-injection, and greatly simplifying the operation process. The intuitive and convenient touchscreen design allows even beginners to quickly master the basic operation of the equipment. The micro-stepping motor 4 is an ultra-precision motor from Panasonic, Japan, with extremely high positioning accuracy. The fixed rod 403 is made of stainless steel with a finely ground surface, and the needle 2 is a glass capillary, ensuring injection accuracy while also possessing strong chemical corrosion resistance.
[0032] Reference Figure 1A wire 503 is provided on one side of the control console 5, and a controller 6 is installed at the other end of the wire 503. The controller 6 has two sets of mounting slots 601 inside, and a pedal 602 is installed inside each of the two sets of mounting slots 601. A spring 603 is provided at the bottom of each set of pedals 602, and one end of each set of pedals 602 is hinged to the controller 6. A protective frame 406 is installed on the outside of the micro-stepping motor 4, and the connecting sleeve 402 is made of sound-absorbing sponge material. A switch 104 and an indicator light 102 are installed on the outside of the pump head 1, and both the switch 104 and the indicator light 102 are electrically connected to the control console 5. By setting... The wire 503 makes it easier for operators to operate the pump head 1 and greatly simplifies the operation process. Parameters can be adjusted during injection, effectively improving the practicality of the device. The screw 401 provides vibration damping and noise insulation for the micro-stepping motor 4 during operation, minimizing interference with operators and improving safety. The switch 104 makes it easier for operators to control the pump head 1, and the indicator light 102 promptly indicates the current working status of the pump head 1, further enhancing the device's practicality.
[0033] Reference Figure 1 A displacement sensor 405 is sleeved on the outside of the fixed rod 403, and the displacement sensor 405 is electrically connected to the control console 5. By setting the displacement sensor 405, the moving length of the fixed rod 403 can be further accurately measured during use, so as to achieve precise control of the needle's extraction of the medicine. Multiple sets of counterweights 105 are installed inside the pump head 1. By setting the counterweights 105, the balance of the pump head 1 can be improved during use, preventing the pump head 1 from shifting due to an unstable center of gravity during use or placement. An anti-slip sleeve 103 is sleeved on the outside of the pump head 1, and the surfaces of both sets of pedals 602 are provided with anti-slip layers 604. By setting the anti-slip sleeve 103 and anti-slip layers 604, an effective anti-slip effect can be achieved during use, improving the stability of the device operation.
[0034] Working principle: By setting up the control console 5, the needle 2 is made of glass capillary with an ultra-fine diameter to reduce damage to biological tissues. The screw 401 and the fixed rod 403 inside the pump head 1 work together to ensure micron-level motion control precision. The total stroke of the fixed rod 403 is 25.40mm, ensuring a sufficient injection range. The pump head 1 is equipped with a micro-stepping motor 4, which can achieve a minimum volume resolution of 0.01nL. The control console 5 integrates a display screen 501 and control buttons 502, which can support switching between multiple working modes, including starting point positioning, emptying, sampling, programming, and simultaneous injection in groups. The injection volume can be easily set through the display screen 501. By setting up the wires 503, it is more convenient for the staff to operate the pump head 1 during use, and the operation process can be greatly simplified. Parameters can also be adjusted during the injection process, effectively improving the practicality of the device.
[0035] Among them, the micro-stepping motor 4 is an ultra-precision motor from Panasonic Corporation of Japan, which has extremely high positioning accuracy. The fixing rod 403 is made of stainless steel with a finely ground surface. The needle 2 is a glass capillary, which ensures injection accuracy while also having strong chemical corrosion resistance. By setting the screw 401, vibration reduction and sound insulation can be achieved for the micro-stepping motor 4 during operation, minimizing interference to the staff and improving safety.
[0036] Meanwhile, by setting up a displacement sensor 405, the moving length of the fixed rod 403 can be further accurately measured during use, so as to achieve precise control of the needle's extraction of the medicine.
[0037] In addition, by setting switch 104, it is more convenient for operators to control pump head 1. The indicator light 102 can indicate the current working status of pump head 1 in a timely manner, improving the practicality of the device. By setting counterweight 105, the balance of pump head 1 can be improved during use, preventing the pump head 1 from shifting due to an unstable center of gravity during use or placement. By setting anti-slip sleeve 103 and anti-slip layer 604, it can effectively prevent slipping during use, improving the stability of device operation.
[0038] The above description is merely a preferred embodiment of this application and is not intended to limit this application. Although this application has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this application should be included within the protection scope of this application.
Claims
1. A glass microelectrode injection pump, comprising a pump head (1), characterized in that, The pump head (1) has an internal mounting cavity (101). Inside the mounting cavity (101) are a liquid suction chamber (3) and a micro stepper motor (4). One end of the liquid suction chamber (3) is fitted with a needle (2), and the other end of the needle (2) extends through one side of the pump head (1) to the outside. The output end of the micro stepper motor (4) is fitted with a screw (401). Inside the liquid suction chamber (3) is a piston (301), and outside the screw (401) is a connecting sleeve. (402), a fixing rod (403) is fixedly connected to one side of the connecting sleeve (402), and a piston (301) is fixedly connected to the other end of the fixing rod (403). A connection port (106) is installed at one end of the pump head (1), and a control console (5) is fixedly installed at the other end of the connection port (106). A display screen (501) and multiple control buttons (502) are provided on the outside of the control console (5). The control console (5) is electrically connected to the micro stepper motor (4).
2. The glass microelectrode injection pump according to claim 1, characterized in that, A wire (503) is provided on one side of the control console (5), and a controller (6) is installed at the other end of the wire (503). The controller (6) has two sets of mounting slots (601) inside, and a pedal (602) is installed inside each of the two sets of mounting slots (601). A spring (603) is provided at the bottom of each of the two sets of pedals (602), and one end of each set of pedals (602) is hinged to the controller (6).
3. The glass microelectrode injection pump according to claim 1, characterized in that, The micro stepper motor (4) is equipped with a protective frame (406), and the connecting sleeve (402) is made of silent sponge material.
4. A glass microelectrode injection pump according to claim 1, characterized in that, A displacement sensor (405) is sleeved on the outside of the fixed rod (403), and the displacement sensor (405) is electrically connected to the control console (5).
5. A glass microelectrode injection pump according to claim 1, characterized in that, A switch (104) and an indicator light (102) are installed on the outside of the pump head (1), and both the switch (104) and the indicator light (102) are electrically connected to the control console (5).
6. A glass microelectrode injection pump according to claim 1, characterized in that, Multiple sets of counterweights (105) are installed inside the pump head (1).
7. A glass microelectrode injection pump according to claim 2, characterized in that, The pump head (1) is fitted with an anti-slip sleeve (103), and the surfaces of both sets of pedals (602) are provided with an anti-slip layer (604).