Model for demonstrating ribosome translation

By designing a transparent double sliding rail and magnetic connection in a mimicry ribosome model, the amino acid dehydration condensation process is simulated, solving the problem of poor demonstration effect of amino acid dehydration condensation in existing models and improving teaching effectiveness.

CN223638039UActive Publication Date: 2025-12-05汪君洋 +1
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Patent Information

Application Number
CN202422863656.8
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-11-24
Publication Date
2025-12-05
Estimated Expiration
2034-11-24

AI Technical Summary

Technical Problem

Existing ribosome teaching models are not very effective in demonstrating the dehydration condensation of amino acids, and students do not have a very intuitive understanding of the process, which affects the teaching effect.

Method used

A model comprising mimicry ribosomes, mimicry amino acids, mimicry tRNA, and mimicry aminoacyl-tRNA was designed. Using transparent double sliding rails and magnetic connections, the dehydration condensation process of amino acids was simulated by the sliding of mimicry amino acids and mimicry tRNA in the rails.

Benefits of technology

This demonstration of amino acid dehydration condensation, which is simple in structure and easy to operate, enhanced students' hands-on skills and understanding of the process.

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Abstract

The utility model discloses a model for demonstrating ribosome translation. The model comprises mimic ribosome; mimicry amino acids; mimic tRNA (transfer ribonucleic acid); the mimicry ribosome comprises three parts: a mimicry large subunit, a mimicry large subunit, a mimicry small subunit and a mimicry aminoacyl tRNA. A transparent double-slide rail piece; the mimicry small subunit and the mimicry large subunit are positioned above the transparent double-slide rail piece and are connected with each other in a bonding manner; the mimic small subunit is located below the transparent double-sliding-rail part and is connected with the transparent double-sliding-rail part in a bonding mode, the mimic tRNA and the mimic amino acid can be connected through magnetic attraction, the transparent double-sliding-rail part is provided with an upper sliding rail and a lower sliding rail, the upper sliding rail is longer than the lower sliding rail, and the mimic amino acid can slide in the upper sliding rail; the mimic tRNA can slide in the lower slide rail; the mimicry aminoacyl tRNA can slide in the upper sliding rail and the lower sliding rail of the transparent double-sliding-rail piece at the same time. The amino acid dehydration condensation demonstration device has the advantages of being simple in structure, easy to operate, capable of visually demonstrating the process of amino acid dehydration condensation and convenient for students to understand.
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Description

TECHNICAL FIELD

[0001] The utility model belongs to the technical field of teaching equipment, and specifically relates to a model for demonstrating ribosome translation. BACKGROUND

[0002] At present, the ribosome teaching models that have been declared and passed are mostly inclined to demonstrate the pairing of codons and anticodons, for example, the genetic information translation model for teaching disclosed in Chinese patent application CN218768499U. The demonstration effect of the amino acid dehydration condensation step is poor, and students' experience of the process is not intuitive enough, which affects the teaching effect. The utility model can better solve the problem. SUMMARY

[0003] The utility model aims at overcoming the defects in the background art, and provides a ribosome protein synthesis demonstration model that is simple in structure and convenient to operate.

[0004] The utility model solves the technical problem by adopting the following technical scheme:

[0005] A model for demonstrating ribosome translation, comprising: a mimic ribosome; mimic amino acids; mimic tRNA; and mimic aminoacyl tRNA, wherein the mimic ribosome is composed of three parts: a mimic large subunit, a transparent double slide rail, and a mimic small subunit, the mimic large subunit is located above the transparent double slide rail and is connected thereto by adhesion, the mimic small subunit is located below the transparent double slide rail and is connected thereto by adhesion, the mimic tRNA and the mimic amino acids are magnetically connected, the transparent double slide rail comprises two slide rails, i.e., an upper slide rail and a lower slide rail, and the lower slide rail is inwardly tapered at the upper portion.

[0006] The material of the mimic amino acids is iron.

[0007] The shape of the mimic amino acids is a sphere.

[0008] The top of the mimic tRNA is provided with a magnet.

[0009] The two slide rails at one end of the transparent double slide rail are flush, and the upper slide rail is longer than the lower slide rail at the other end.

[0010] The angle between the upper slide rail of the transparent double slide rail, which is longer than the lower slide rail, and the horizontal plane is 10 degrees.

[0011] Compared with the prior art, the utility model has the following beneficial effects:

[0012] 1. By designing the double slide rail piece, the quasi amino acid can slide in the upper slide rail; the quasi tRNA can slide in the lower slide rail; the quasi aminoacyl tRNA can simultaneously slide in the upper slide rail and the lower slide rail of the transparent double slide rail piece. The quasi amino acid and the quasi tRNA can simultaneously slide in the upper slide rail and the lower slide rail of the transparent double slide rail piece after being magnetically connected.

[0013] 2. By designing the inward collection of the upper part of the lower slide rail, the quasi tRNA sliding in the lower slide rail is prevented from being dislocated upward.

[0014] 3. By designing the upper slide rail longer than the lower slide rail section, the quasi amino acid can be pushed by the quasi aminoacyl tRNA under the action of external force to form an acute angle obliquely upward along the upper slide rail longer than the lower slide rail section, the quasi tRNA is limited by the inward collection of the upper part of the lower slide rail and cannot continue to accompany the quasi amino acid obliquely upward, and with the angular upward movement of the upper slide rail, the magnetic attraction between the quasi amino acid and the quasi tRNA will be interrupted so that they are separated, and this step can simulate the dehydration condensation of amino acids.

[0015] The utility model has remarkable advantages and beneficial effects compared with prior art: the utility model simple structure, one person can complete the demonstration process, can increase the user's hands-on ability, strengthen the student's understanding of amino acid dehydration condensation. BRIEF DESCRIPTION OF DRAWINGS

[0016] Figure 1 is the schematic diagram of each part of the utility model

[0017] Figure 2 is the front view of the quasi ribosome 1

[0018] Figure 3 is the left view of the quasi ribosome 1

[0019] Figure 4 is the front view of the quasi tRNA 3

[0020] Figure 5 is the left view of the quasi tRNA 3

[0021] Figure 6 is the front view of the quasi aminoacyl tRNA 4

[0022] Figure 7 is the left view of the quasi aminoacyl tRNA 4

[0023] Figure 8 is the cross-sectional view of the quasi amino acid 2 and the quasi tRNA 3 when they are not separated

[0024] Figure 9 is the cross-sectional view of the quasi amino acid 2 and the quasi tRNA 3 when they are separated

[0025] In the figure: mimic ribosome 1; mimic amino acid 2; mimic tRNA 3; mimic aminoacyl tRNA 4; mimic large subunit 1-1; transparent double slide 1-2; mimic small subunit 1-3. DETAILED DESCRIPTION

[0026] The utility model is further described in detail below in combination with the drawings and specific embodiments:

[0027] Please refer to Figures 1-7 The model for demonstrating ribosome translation comprises four parts: mimic ribosome 1; mimic amino acid 2; mimic tRNA 3; mimic aminoacyl tRNA 4. The mimic ribosome 1 is composed of mimic large subunit 1-1; double slide 1-2; mimic small subunit 1-3. The mimic large subunit 1-1 is above the double slide 1-2, and the two are adhesively connected; the mimic small subunit 1-3 is below the double slide 1-2, and the two are adhesively connected. Before use, the double slide 1-2 should be adhesively connected with the mimic large subunit 1-1 and the mimic small subunit 1-3.

[0028] Please refer to Figure 8 In the demonstration, first, the mimic amino acid 2 is adhesively connected with the mimic tRNA 3, then the double slide 1-2 is placed into the double slide 1-2 from the parallel ends of the two slides, with the mimic amino acid 2 in the upper slide and the mimic tRNA 3 in the lower slide, and then the mimic aminoacyl tRNA 4 is placed, and the mimic aminoacyl tRNA 4 is pushed by external force to move along the double slide 1-2 to the upper slide longer than the lower slide end, so as to indirectly push the mimic amino acid 2 and the mimic tRNA 3 forward. This step can simulate the tRNA carrying the amino acid to the ribosome.

[0029] In the parallel segment of the upper slide and the lower slide of the double slide 1-2, the mimic amino acid 2 can slide in the upper slide of the double slide 1-2, and the mimic tRNA 3 can slide in the lower slide of the double slide 1-2, and the mimic amino acid 2 and the mimic tRNA 3 are adhesively connected.

[0030] Please refer to Figure 9 Continue the demonstration operation, when the mimic aminoacyl tRNA 4 pushes the mimic amino acid 2 and the mimic tRNA 3 to the upper slide longer than the lower slide segment, the mimic amino acid 2 can be pushed by the mimic aminoacyl tRNA 4 under the action of external force to form an acute angle obliquely upwards along the upper slide longer than the lower slide segment, and the mimic tRNA 3 is limited by the inward collection of the upper part of the lower slide and cannot continue to accompany the mimic amino acid 2 obliquely upwards, and with the angular upward movement of the upper slide, the adhesion between the mimic amino acid 2 and the mimic tRNA 3 will be interrupted, so that they are separated, and this step can simulate the dehydration condensation of the amino acid.

Claims

1. A model demonstrating ribosomal translation, characterized by: Comprise: Quasi ribosome (1); Quasi amino acid (2); Quasi tRNA (3); Quasi aminoacyl tRNA (4), the quasi ribosome is composed of three parts: quasi large subunit (1-1); Transparent double slide rail piece (1-2); Quasi small subunit (1-3), quasi large subunit (1-1) is located above transparent double slide rail piece (1-2), and the two are adhesively connected; Quasi small subunit (1-3) is located below transparent double slide rail piece (1-2), and the two are adhesively connected, quasi tRNA (3) and quasi amino acid (2) can be magnetically connected, transparent double slide rail piece (1-2) includes two slides of upper slide rail and lower slide rail, and the upper part of lower slide rail is inwardly recessed.

2. A model demonstrating ribosomal translation according to claim 1, wherein: The material of quasi amino acid (2) is iron.

3. The model of ribosomal translation of claim 1, wherein: The shape of quasi amino acid (2) is a sphere.

4. The model of ribosomal translation of claim 1, wherein: The top of quasi tRNA (3) is provided with a magnet.

5. The model of ribosomal translation of claim 1, wherein: The upper slide rail and the lower slide rail at one end of the transparent double slide rail piece (1-2) are flush, and the upper slide rail at one end is longer than the lower slide rail.

6. A model demonstrating ribosomal translation according to claim 5, wherein: The angle between the upper slide rail longer than the lower slide rail section of the transparent double slide rail piece (1-2) and the horizontal plane is 10 degrees.

Citation Information

Patent Citations

  • Genetic information translation model for teaching

    CN218768499U