Shaking type embolism microsphere filling and uniform mixing device

By designing a rocking embolized microsphere filling device with an arc-shaped container bottom and a pagoda-shaped head structure, the problem of uneven sedimentation of microspheres and physiological sodium chloride solution suspensions was solved, achieving a high-efficiency and low-cost filling process.

CN223641709UActive Publication Date: 2025-12-09CANYON MEDICAL INC
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Patent Information

Application Number
CN202422960012.0
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-03
Publication Date
2025-12-09
Estimated Expiration
2034-12-03

AI Technical Summary

Technical Problem

In existing technologies, the suspension of microspheres and physiological sodium chloride solution is prone to uneven sedimentation during the filling process, resulting in residual material. Furthermore, it requires multiple operators, increasing labor costs and reducing efficiency.

Method used

A shaking-type embolized microsphere filling and mixing device is designed. It adopts an arc-shaped container bottom and a pagoda head structure, combined with a vibration motor and a damping device. The device achieves uniform filling of suspension by shaking, avoiding tail material residue and improving efficiency.

Benefits of technology

It achieves uniform filling of suspensions, reduces residual material, improves filling efficiency, and allows for observation of product balance and mixing status through transparent containers, thereby reducing labor costs.

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Abstract

The utility model relates to the technical field of suspension filling, in particular to a shaking type embolism microsphere filling and mixing device which comprises a supporting frame, a fixing support, a sealing tank and a sealing cover, the supporting frame is fixed, the fixing support is installed on the supporting frame, the sealing tank is installed on the fixing support, and the sealing cover is installed on the sealing tank. One side of the sealing tank and one side of the fixing support are made of transparent materials. The upper end of the sealing tank is cylindrical, the lower end of the sealing tank is a pagoda head, and the end of the pagoda head is connected with a conveying hose. According to the novel uniform mixing device, the container filled with the product to be filled is arranged on the supporting frame and is matched with the vibration motor to shake the product to be filled at a constant frequency, so that the product can be well mixed even in the tailing stage, and the container filled with the product to be filled is a transparent container, so that the balance of the product to be filled is convenient to observe; therefore, the filling efficiency is improved.
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Description

Technical Field

[0001] This utility model relates to the field of suspension filling technology, specifically to a shaking-type embolized microsphere filling and mixing device. Background Technology

[0002] Polyvinyl alcohol (PVA) embolization microspheres are produced by mixing microspheres and physiological sodium chloride solution in a specific ratio, then uniformly filling the solution into injection vials using a linear pump, and finally sealing with rubber stoppers and aluminum-plastic caps. Because the PVA embolization microspheres to be filled are a suspension, they will immediately settle upon standing, ultimately leading to uneven filling results.

[0003] Currently, a suspension of microspheres and physiological sodium chloride solution is placed in a beaker, stirred with a magnetic stirrer, and then one end of a linear pump is submerged below the surface of the suspension, while the other end is used to fill the vial. However, this method has a drawback: during the tail-filling stage, the magnetic stirrer struggles to achieve proper mixing due to the lowered suspension level. Furthermore, the commonly used flat-bottomed beakers and pump tubing make it difficult to completely fill the tail-filling area. During filling, the product-to-be-filled area and the filling area are often located at opposite ends of the linear pump, requiring one person to hold the pump tubing in the product-to-be-filled area while another person fills the product in the filling area, increasing labor costs and reducing filling efficiency.

[0004] Therefore, this utility model provides a shaking-type embolization microsphere filling and mixing device to solve the above problems. Utility Model Content

[0005] The technical problem this invention aims to solve is as follows: Currently, a suspension of microspheres and physiological sodium chloride solution is placed in a beaker, stirred with a magnetic stirrer, and then one end of a linear pump is submerged below the surface of the suspension, while the other end is used to fill the injection vial. However, this method suffers from a tail-filling stage. Due to the lowered suspension level, the magnetic stirrer struggles to achieve thorough mixing. Furthermore, the commonly used flat-bottomed beakers and pump tubing make it difficult to completely fill the tail-filling stage. During filling, the product-to-be-filled area and the filling area are often located at opposite ends of the linear pump, requiring one person to hold the pump tubing in the product-to-be-filled area while another person fills the product in the filling area, increasing labor costs and reducing filling efficiency.

[0006] This utility model provides the following technical solution: a shaking-type embolization microsphere filling and mixing device, including a support frame, a fixed bracket, a sealed container and a sealed cap, wherein the support frame is fixed, the fixed bracket is installed on the support frame, the sealed container is installed on the fixed bracket, and the sealed container is installed on the sealed cap;

[0007] The sealed container is cylindrical at the top and arc-shaped at the bottom. A pagoda head is installed at the bottom of the sealed container, and a delivery hose is connected to the end of the pagoda head.

[0008] Preferably, the fixed bracket is symmetrically equipped with fixing rings, and the fixing rings are provided with fixing holes arranged in an array around their perimeter, with fixing bolts installed in the fixing holes.

[0009] Preferably, two sets of fixing rings are provided and symmetrically installed at both ends of the sealed container.

[0010] Preferably, the vibration uniform device includes a vibration motor, a damping telescopic rod, and a damping spring. The vibration motor is installed at the bottom of the support frame, and there are two damping telescopic rods symmetrically installed between the two support plates of the support frame. A damping spring is installed on each damping telescopic rod.

[0011] The beneficial effects of this utility model are as follows:

[0012] This invention employs a novel mixing device. The container's bottom is designed with an arc shape and fitted with a pagoda-shaped head connected to a linear pump tube, allowing for complete product filling and preventing residue buildup. Simultaneously, shaking is used to disperse suspended matter. The container containing the product is placed on a support frame and shaken at a constant frequency by a vibrating motor. This ensures good product mixing even during the residue stage. Furthermore, the transparent container facilitates observation of the remaining product and the mixing status, thereby improving filling efficiency. Attached Figure Description

[0013] To more clearly illustrate the specific embodiments of this utility model or the technical solutions in the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this utility model. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0014] Figure 1 This is a schematic diagram of the overall design of this utility model;

[0015] Figure 2 This is a schematic diagram of the fixing bracket of this utility model;

[0016] Figure 3 This is a schematic diagram showing the installation position of the fixed bracket of this utility model;

[0017] Figure 4 This is a schematic diagram showing the installation position of the vibration homogenizing device of this utility model.

[0018] In the diagram: 1. Support frame; 2. Fixed bracket; 21. Fixing ring; 22. Fixing hole; 23. Fixing bolt; 3. Sealed container; 31. Pagoda head; 4. Sealing cover; 5. Conveying hose; 6. Vibration uniform device; 61. Vibration motor; 62. Shock-absorbing telescopic rod; 63. Shock-absorbing spring. Detailed Implementation

[0019] To make the objectives, technical solutions, and advantages of the embodiments of this utility model clearer, the technical solutions of the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this utility model. Therefore, the following detailed description of the embodiments of this utility model is not intended to limit the scope of the claimed utility model, but merely represents some embodiments of this utility model. All other embodiments obtained by those skilled in the art based on the embodiments of this utility model without creative effort are within the scope of protection of this utility model.

[0020] It should be noted that similar labels and letters in the following figures indicate similar items. Therefore, once an item is defined in one figure, it does not need to be further defined and explained in subsequent figures.

[0021] In the description of this utility model, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," "outer," and "back side," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, or the orientation or positional relationship in which the product of this utility model is conventionally placed during use. These terms are used only for the convenience of describing this utility model and for simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation; therefore, they should not be construed as limitations on this utility model.

[0022] It should also be noted that, in the description of this utility model, unless otherwise explicitly specified and limited, the terms "set," "install," "connect," and "link" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0023] This disclosure aims to address the current method of mixing microspheres and physiological sodium chloride solution in a beaker using a magnetic stirrer, followed by submerging one end of a linear pump below the surface of the suspension and filling the vial with the other end. However, this method suffers from a tail-filling stage where the magnetic stirrer struggles to achieve proper mixing due to the lowered suspension level. Furthermore, the commonly used flat-bottomed beakers make it difficult for the pump tube to completely fill the tail-filling area. During filling, the product area and the filling area are often located at opposite ends of the linear pump, requiring one person to hold the pump tube in the product area while another person fills the product in the filling area, increasing labor costs and reducing filling efficiency. Therefore, this disclosure proposes a shaking-type embolized microsphere filling and mixing device. This device features a new mixing mechanism with a rounded bottom and a pagoda-shaped connector at the bottom, connecting to the linear pump tube. This allows for complete product filling, avoids tail-filling residue, and utilizes shaking to disperse the suspension. The container containing the product to be filled is placed on a support frame and shaken at a constant frequency with a vibration motor. This ensures that the product is well mixed even in the final stage. Furthermore, the container is transparent, making it easy to observe the remaining amount of product and the mixing status, thereby improving filling efficiency.

[0024] like Figures 1 to 4 As shown, a shaking-type embolic microsphere filling and mixing device includes a support frame 1, a fixed bracket 2, a sealed container 3, and a sealing cap 4. The support frame 1 is fixed, the fixed bracket 2 is installed on the support frame 1, the sealed container 3 is installed on the fixed bracket 2, and the sealing cap 4 is installed on the sealed container 3. At the same time, a conventional vibration motor 61 is set outside the sealed container 3 to cooperate with the sealed container to achieve a uniform effect through vibration.

[0025] The sealed container 3 is made of transparent material; the upper end of the sealed container 3 is cylindrical and the lower end is arc-shaped. A pagoda head 31 is installed at the bottom of the sealed container 3, and a conveying hose 5 is connected to the end of the pagoda head 3. Making the sealed container 3 and the fixed bracket 2 transparent is suitable for observing the remaining amount of the product to be filled and the mixing status, thereby allowing the staff to better control the switching of the vibration motor 61. The pagoda head 31 at the bottom of the sealed container 3 is used to better discharge the tail material under the action of gravity.

[0026] By designing a novel mixing device with a rounded bottom and a pagoda-shaped head connected to a linear pump tube, the product can be fully filled, preventing residue buildup. Shaking is used to disperse suspended solids. The container holding the product is placed on a support frame and shaken at a constant frequency by a vibrating motor. This ensures good mixing even in the residue stage. Furthermore, the transparent container allows for easy observation of the remaining product and the mixing status, thus improving filling efficiency.

[0027] like Figures 2 to 3 As shown, fixing rings 21 are symmetrically installed on the fixing bracket 2. Fixing holes 22 are arranged around the fixing rings 21, and fixing bolts 23 are installed in the fixing holes 22. The fixing method described above can be used to fix the container, and the size can be adjusted to facilitate the insertion and removal of containers of different volumes.

[0028] The fixing bracket 2 has two sets. One set is located above the sealing container 3 to fix the sealing container 3 and the sealing cover 4; the other set is located below the sealing container 3 to fix the sealing container 3 and the support frame 1.

[0029] like Figure 1 As shown, two sets of fixing rings 21 are symmetrically installed at both ends of the sealed container 3. The fixing ring 21 located above the sealed container 3 is used to fix the sealing cap 4 to the sealed container 3; the fixing ring 21 located below the sealed container 3 is used to fix the sealed container 3 to the support frame 1. The fixing rings 21 can better fix the sealed container 3. At the same time, the fixing rings 21 can also minimize the obstruction of the sealed container 3, thereby making it easier to observe the remaining amount of the product to be filled and the mixing status, thus improving the filling efficiency.

[0030] like Figure 4 As shown, the vibration homogenizing device 6 includes a vibration motor 61, a shock-absorbing telescopic rod 62, and a shock-absorbing spring 63. The vibration motor 61 is installed at the bottom of the support frame 1 and is used to vibrate and drive the shock-absorbing telescopic rod 62 to retract. There are two shock-absorbing telescopic rods 62, which are symmetrically installed between the two support plates of the support frame 1. The extension and retraction of the shock-absorbing telescopic rods 62 are used to drive the sealed tank 3 to shake with a shaking amplitude of 1-2 cm. The shock-absorbing spring 63 is installed on the shock-absorbing telescopic rod 62. The shock-absorbing spring 63 is used to buffer the impact force generated by shaking and also to reset the shock-absorbing telescopic rod 62.

[0031] The overall working process is as follows: The operator places the sealed container 3 into the fixing ring 21 inside the fixing bracket 2 located on the support frame 1. After the sealed container 3 is initially fixed, the fixing bolt 23 is adjusted to fix the sealed container 3 on the support frame 1. After the sealed container 3 is fixed, the operator opens the sealing cover 4 and adds the raw material into the sealed container 3. After adding the raw material, the fixing bolt 23 at the top of the sealed container 3 is adjusted to fix the sealing cover 4 onto the sealed container 3. At this time, the operator turns on the vibration motor to achieve a shaking effect. While shaking, the mixed liquid is sent out through the connection between the tip of the sealed container 3 and the delivery hose 5.

[0032] Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed utility model. The scope of protection of this utility model is defined by the appended claims and their equivalents.

Claims

1. A shaking-type embolic microsphere filling and mixing device, characterized in that, The device includes a support frame (1), a fixed bracket (2), a sealed container (3), a sealing cap (4), and a vibration homogenizing device (6). The support frame (1) is fixed, the fixed bracket (2) is installed on the support frame (1), the sealed container (3) is installed on the fixed bracket (2), and the sealing cap (4) is installed on the sealed container (3). The vibration homogenizing device (6) is installed at the bottom of the support frame (1). The sealed container (3) is made of transparent material; the upper end of the sealed container (3) is cylindrical and the lower end is arc-shaped. A pagoda head (31) is installed at the bottom of the sealed container (3), and a delivery hose (5) is connected to the end of the pagoda head (31).

2. The shaking-type embolic microsphere filling and mixing device according to claim 1, characterized in that: The fixed bracket (2) is symmetrically equipped with fixing rings (21), and fixing holes (22) are arranged around the fixing rings (21). Fixing bolts (23) are installed in the fixing holes (22).

3. The shaking-type embolic microsphere filling and mixing device according to claim 2, characterized in that: The fixing ring (21) is provided in two sets and is symmetrically installed at both ends of the sealing tank (3).

4. The shaking-type embolic microsphere filling and mixing device according to claim 3, characterized in that: The vibration uniform device (6) includes a vibration motor (61), a shock-absorbing telescopic rod (62), and a shock-absorbing spring (63). The vibration motor (61) is installed at the bottom of the support frame (1). There are two shock-absorbing telescopic rods (62) installed symmetrically between the two support plates of the support frame (1). The shock-absorbing telescopic rods (62) are equipped with shock-absorbing springs (63).