Integrated fermentation tank system with homogenizing function

By directly connecting the homogenizer to the fermentation tank, continuous homogenization of the fermentation broth can be achieved, solving the problems of cumbersome operation and bacterial contamination in traditional methods, and improving processing efficiency and product quality.

CN223646539UActive Publication Date: 2025-12-09COFCOET-ZAVKOM(WUXI) INT BIOCHEMICAL TECH CO LTD +1
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Patent Information

Application Number
CN202423158009.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-20
Publication Date
2025-12-09
Estimated Expiration
2034-12-20

AI Technical Summary

Technical Problem

Traditional methods for homogenizing fermentation broth are cumbersome to operate, require large equipment footprints, and are prone to contamination and bacterial growth, which can affect product quality.

Method used

The homogenizer is directly connected to the fermentation tank to achieve continuous homogenization of the fermentation broth. The continuous homogenization of the fermentation broth is carried out through the circulation pipeline between the high-pressure homogenizer and the fermentation tank.

Benefits of technology

Simplify the operation process, improve processing efficiency, reduce the risk of contamination, enhance homogenization and fermentation effects, and improve the extraction efficiency and yield of the target product.

✦ Generated by Eureka AI based on patent content.

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Abstract

An integrated fermentation tank system with a homogenizing function comprises a fermentation tank, the fermentation tank is communicated with a feeding port of a filtering device through a pipeline, a discharging port of the filtering device is communicated with a feeding port of a high-pressure homogenizer through a pipeline, and a discharging port of the high-pressure homogenizer is communicated with the fermentation tank through a circulating pipeline. According to the system disclosed by the utility model, the homogenizer is connected with the fermentation tank in a pipeline connection manner, so that continuous homogenization treatment of fermentation liquor is realized, the fermentation effect, the treatment efficiency of the fermentation liquor and the homogenization effect are remarkably improved, and meanwhile, the possibility of bacterial contamination of the fermentation tank is greatly reduced. The system is suitable for multiple fields of biological medicine, food industry, daily chemical care products and the like, has the advantages of simplicity and convenience in operation, high efficiency, good homogenizing effect and the like, and belongs to the field of biochemical manufacturing equipment.
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Description

Technical Field

[0001] This utility model relates to an integrated fermenter system with homogenization, belonging to the field of fermentation equipment technology. Background Technology

[0002] In the fields of biomedicine and food processing, homogenization of fermentation broth is a crucial process step. Traditional methods typically involve draining the fermentation broth from the fermenter, transporting it through pipelines to a homogenizer, and then returning the homogenized broth to the fermenter. This method is not only cumbersome and requires a large equipment footprint, but it also easily leads to contamination of the fermentation broth during transport, affecting the quality of the final product. Furthermore, most culture media suffer from incomplete sterilization during actual sterilization due to incomplete dissolution and flocculation during heating, resulting in repeated contamination during fermentation. Utility Model Content

[0003] To overcome the shortcomings of the prior art, the present invention aims to disclose an integrated fermenter system with homogenizer, which realizes continuous homogenization of fermentation broth by directly connecting the homogenizer to the fermenter.

[0004] This utility model discloses an integrated fermentation tank system with homogenization, characterized in that: it includes a fermentation tank, which is connected to the inlet of a filter device through a pipeline, the outlet of the filter device is connected to the inlet of a high-pressure homogenizer through a pipeline, and the outlet of the high-pressure homogenizer is connected to the fermentation tank through a circulation pipeline.

[0005] The preferred technical solution is as follows: the bottom of the fermenter is provided with a discharge pipe, the discharge pipe is provided with a first diaphragm valve, and the discharge pipe is provided with a discharge port.

[0006] The preferred technical solution is that a control valve is provided on the connecting pipeline between the fermenter and the filtration device.

[0007] The preferred technical solution is that a transfer pump is provided on the connecting pipeline between the filtration device and the high-pressure homogenizer.

[0008] The preferred technical solution is that a second diaphragm valve is provided on the circulation pipeline.

[0009] The preferred technical solution is as follows: the bottom of the filter device is provided with a slag discharge pipe, the slag discharge pipe is provided with a slag discharge valve, and the slag discharge pipe is provided with a slag discharge port.

[0010] Due to the application of the above technical solution, the beneficial effects of this utility model compared with the prior art are as follows:

[0011] The advantages of this utility model are as follows:

[0012] 1. Easy to operate: Since the homogenizer is directly connected to the fermentation tank, there is no need to take the fermentation liquid out of the fermentation tank and then transfer it to the homogenizer, so the operation is simpler and faster.

[0013] 2. High efficiency: By continuously feeding the fermentation broth into the homogenizer for homogenization, the processing efficiency of the fermentation broth is significantly improved.

[0014] 3. Excellent homogenization effect: High-pressure homogenizers can break down and evenly disperse solid particles and bubbles in fermentation broth, thereby achieving better homogenization effect.

[0015] 4. Reduce the risk of contamination: Running homogenization before sterilization can break down solid particles in the culture medium, improve the efficiency of sterilization, and reduce the risk of microbial contamination; running homogenization after sterilization can break down the cell walls of microorganisms that remain when sterilization is incomplete, further reducing the possibility of contamination during fermentation.

[0016] 5. Improve fermentation effect: The homogenization system running simultaneously after sterilization can crush flocculent matter and large particles in the fermentation broth, thereby improving the utilization rate of nutrients by microorganisms.

[0017] 6. Improve the extraction effect in the later stage: After the fermentation is completed, the homogenization is started, which can break up the crystals of the target product in high-density fermentation. At the same time, the cell is broken to promote the release of intracellular residual products into the fermentation broth, thereby increasing the content of the target product in the fermentation broth and improving the extraction efficiency and yield. Attached Figure Description

[0018] To more clearly illustrate the specific embodiments of this utility model or the technical solutions in the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this utility model. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0019] Figure 1 This is a schematic diagram of the structure of this utility model.

[0020] In the attached diagram above, 1 is the fermentation tank; 2 is the feed inlet; 3 is the first diaphragm valve; 4 is the discharge outlet; 5 is the control valve; 6 is the transfer pump; 7 is the high-pressure homogenizer; 8 is the circulation pipeline; 9 is the second diaphragm valve; 10 is the filter device; 11 is the slag discharge valve; and 12 is the slag discharge port. Detailed Implementation

[0021] The following specific embodiments illustrate the implementation of this utility model. Those skilled in the art can easily understand other advantages and effects of this utility model from the content disclosed in this specification.

[0022] It should be noted that the terms "first," "second," etc., in the specification, claims, and accompanying drawings of this application are used to distinguish similar objects and are not necessarily used to describe a specific order or sequence. It should be understood that such data can be used interchangeably where appropriate for the purposes of describing embodiments of this application herein. Furthermore, the terms "comprising" and "having," and their synonyms, are intended to cover non-exclusive inclusion; for example, a process, method, system, product, or apparatus that comprises a series of steps or units is not necessarily limited to those steps or units explicitly listed, but may include other steps or units not explicitly listed or inherent to such processes, methods, products, or apparatus.

[0023] In this application, the terms "upper," "lower," "left," "right," "front," "rear," "top," "bottom," "inner," "outer," "middle," "vertical," "horizontal," "lateral," and "longitudinal" indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. These terms are primarily for the purpose of better describing the present invention and its embodiments, and are not intended to limit the indicated device, element, or component to having a specific orientation, or to be constructed and operated in a specific orientation.

[0024] Furthermore, in addition to indicating direction or positional relationship, some of the aforementioned terms may also have other meanings. For example, the term "above" may also be used in some cases to indicate a certain dependency or connection relationship. Those skilled in the art can understand the specific meaning of these terms in this utility model according to the specific circumstances.

[0025] Furthermore, the terms "installation," "setting," "equipped with," "connection," "linking," "fitting," and "fitting" should be interpreted broadly. For example, "connection" can be a fixed connection, a detachable connection, or an integral structure; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, or an internal connection between two devices, components, or parts. Similarly, "fitting" can mean completely or partially fitted. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0026] It should be noted that, unless otherwise specified, the embodiments and features described in this application can be combined with each other. This application will now be described in detail with reference to the accompanying drawings and embodiments.

[0027] Example:

[0028] like Figure 1As shown, this utility model discloses an integrated fermentation tank system with homogenization, including a fermentation tank 1. The top of the fermentation tank 1 is provided with a feed inlet 2. The fermentation tank is connected to the feed inlet of a filter device 10 through a pipeline. The discharge outlet of the filter device is connected to the feed inlet of a high-pressure homogenizer 7 through a pipeline. The discharge outlet of the high-pressure homogenizer is connected to the fermentation tank through a circulation pipeline 8.

[0029] A preferred embodiment is as follows: the bottom of the fermenter is provided with a discharge pipe, a first diaphragm valve 3 is provided on the discharge pipe, and a discharge port 4 is provided on the discharge pipe.

[0030] A preferred embodiment is that a control valve 5 is provided on the connecting pipeline between the fermenter and the filtration device.

[0031] A preferred embodiment is that a transfer pump 6 is provided on the connecting pipeline between the filtration device and the high-pressure homogenizer.

[0032] A preferred embodiment is that a second diaphragm valve 9 is provided on the circulation pipeline.

[0033] A preferred embodiment is as follows: the bottom of the filter device is provided with a slag discharge pipe, a slag discharge valve 11 is provided on the slag discharge pipe, and a slag discharge port 12 is provided on the slag discharge pipe.

[0034] The culture medium enters the fermenter through inlet 2.

[0035] When homogenization is required, the culture medium and fermentation broth are pumped from the fermenter into the high-pressure homogenizer via pipelines and transfer pumps. After homogenization, they are returned to the fermenter via circulation pipes.

[0036] This invention provides an integrated fermenter system with homogenizer, which can circulate the culture medium and fermentation broth. Starting the system at different stages of fermentation will have beneficial effects: ① Simultaneously starting the fermenter's agitator, transfer pump, and homogenizer before sterilization ensures thorough mixing and dissolution of the materials; ② Sterilizing the entire system simultaneously during sterilization ensures that the homogenizer, activated after sterilization, breaks down and evenly disperses some of the precipitates and flocs generated during the high-temperature, high-pressure sterilization process, improving sterilization efficiency; ③ Activating the homogenizer after fermentation breaks down the high-density fermentation target product crystals and simultaneously breaks down the cell bodies, promoting the release of intracellular residual products into the fermentation broth, increasing the target product content in the fermentation broth.

[0037] This invention integrates fermentation, homogenization, and slag removal functions into a single system through ingenious design, achieving automation, high efficiency, and intelligence in the fermentation process. The final product obtained after processing by this system is less prone to contamination, has a high yield, and is easy to reprocess, significantly reducing production costs, minimizing the risk of contamination, and simplifying the reprocessing and redissolving process. The equipment is simple to operate, occupies a small area, and boasts high production efficiency, making it easy to scale up and industrialize, thus possessing broad application prospects and market value.

[0038] This utility model discloses an integrated homogenizing fermentation system, which mainly includes a fermenter, a transfer pump, a filtration and slag removal system, and a homogenizer. The fermenter is used for fermentation and is equipped with a distribution pipe, a stirring device, a heating device, and a cooling device to maintain the dissolved oxygen, homogeneity, and suitable temperature of the fermentation broth. The homogenizer is used to homogenize the material and is equipped with a reciprocating plunger pump and a pumping device to break down and uniformly disperse solid particles, crystals, flocculation, and bubbles in the material.

[0039] The key to this invention lies in the direct connection between the fermenter and the homogenizer via a meticulously designed piping system. This piping system includes:

[0040] Discharge Pipe: One end of this pipe connects to the bottom outlet of the fermenter, and the other end connects to the feed inlet of the homogenizer. The discharge pipe is made of corrosion-resistant and high-temperature-resistant SU304 stainless steel to ensure that the fermentation broth is not contaminated or damaged during transport. Meanwhile, the feed pipe is equipped with a diaphragm valve and a slag discharge port, and contains an internal filter screen to prevent oversized particles from entering the homogenizer and damaging the equipment. A slag discharge port is also located below the filter screen to prevent clogging and ensure smooth flow of the feed liquid into the homogenizer.

[0041] Reflux pipe: One end of this pipe connects to the outlet of the homogenizer, and the other end connects to the reflux port on the side wall of the fermenter. The reflux pipe is also made of corrosion-resistant and high-temperature-resistant SU304 stainless steel to ensure that the quality of the material is not affected during the process of returning the homogenized material to the fermenter.

[0042] Connection accessories: To ensure the stability and sealing of the pipeline connection system, this invention employs reliable connection methods such as flange connections or welding connections at the connection between the outlet pipe and the return pipe. Additionally, sealing materials such as gaskets or sealants are provided at the connection points to prevent leakage of the fermentation broth.

[0043] Finally, it should be noted that the above are merely preferred embodiments of the present utility model and are not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. An integrated fermenter system with homogenization, characterized in that: The device includes a fermenter connected to the inlet of a filter via a pipeline, the outlet of the filter connected to the inlet of a high-pressure homogenizer via a pipeline, and the outlet of the high-pressure homogenizer connected to the fermenter via a circulation pipeline.

2. The integrated fermenter system with homogenizer according to claim 1, characterized in that: The fermenter is equipped with a discharge pipe at the bottom, a first diaphragm valve on the discharge pipe, and a discharge port on the discharge pipe.

3. The integrated fermenter system with homogenizer according to claim 1, characterized in that: A control valve is installed on the connecting pipeline between the fermenter and the filtration device.

4. The integrated fermenter system with homogenizer according to claim 1, characterized in that: A transfer pump is installed on the connecting pipeline between the filtration device and the high-pressure homogenizer.

5. The integrated fermenter system with homogenizer according to claim 1, characterized in that: A second diaphragm valve is installed on the circulation pipeline.

6. The integrated fermenter system with homogenizer according to claim 1, characterized in that: The bottom of the filter device is provided with a slag discharge pipe, a slag discharge valve, and a slag discharge port.